Total number of protein in "GO:0016055" GO term: 202
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGRA2 | ADGRA2 | Q96PE1 | Adhesion G protein-coupled receptor A2 | chr8 | GO:0016055 | Not Cancer Driver | No | 140 | 0.105 | 417 | 32 | 0.077 | 0 |
| AES_ENST00000327141 | TLE5 | Q08117 | TLE family member 5 | chr19 | GO:0016055 | Not Cancer Driver | No | 16 | 0.081 | 77 | 7 | 0.091 | 0 |
| AMER1 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0016055 | Census, Compendium | Yes | 234 | 0.206 | 1039 | 219 | 0.211 | 0 |
| AMER2 | AMER2 | Q8N7J2 | APC membrane recruitment protein 2 | chr13 | GO:0016055 | Not Cancer Driver | No | 118 | 0.176 | 663 | 116 | 0.175 | 0 |
| AMER3_ENST00000321420 | AMER3 | Q8N944 | APC membrane recruitment protein 3 | chr2 | GO:0016055 | Not Cancer Driver | No | 244 | 0.283 | 736 | 211 | 0.287 | 0 |
| AMFR | AMFR | Q9UKV5 | E3 ubiquitin-protein ligase AMFR | chr16 | GO:0016055 | Not Cancer Driver | No | 73 | 0.114 | 229 | 30 | 0.131 | 0 |
| AMOTL1 | AMOTL1 | Q8IY63 | Angiomotin-like protein 1 | chr11 | GO:0016055 | Not Cancer Driver | No | 136 | 0.142 | 851 | 121 | 0.142 | 0 |
| AMOTL2_ENST00000422605 | AMOTL2 | Q9Y2J4 | Angiomotin-like protein 2 | chr3 | GO:0016055 | Not Cancer Driver | No | 94 | 0.121 | 741 | 93 | 0.126 | 0 |
| APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0016055 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
| APC2_ENST00000233607 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | GO:0016055 | Not Cancer Driver | No | 117 | 0.051 | 1725 | 78 | 0.045 | 0 |
| APCDD1 | APCDD1 | Q8J025 | Protein APCDD1 | chr18 | GO:0016055 | Not Cancer Driver | No | 73 | 0.142 | 68 | 8 | 0.118 | 1 |
| ARHGEF19 | ARHGEF19 | Q8IW93 | Rho guanine nucleotide exchange factor 19 | chr1 | GO:0016055 | Not Cancer Driver | No | 82 | 0.102 | 365 | 36 | 0.099 | 0 |
| ARL6 | ARL6 | Q9H0F7 | ADP-ribosylation factor-like protein 6 | chr3 | GO:0016055 | Not Cancer Driver | No | 29 | 0.156 | 4 | 0 | 0.0 | 6 |
| AXIN2 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | GO:0016055 | Census, Compendium | Yes | 114 | 0.135 | 547 | 77 | 0.141 | 0 |
| BCL7B_ENST00000223368 | BCL7B | Q9BQE9 | B-cell CLL/lymphoma 7 protein family member B | chr7 | GO:0016055 | Not Cancer Driver | No | 21 | 0.104 | 179 | 20 | 0.112 | 0 |
| BRD7_ENST00000394688 | BRD7 | Q9NPI1 | Bromodomain-containing protein 7 | chr16 | GO:0016055 | Compendium | Yes | 82 | 0.126 | 482 | 57 | 0.118 | 0 |
| BTRC | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | GO:0016055 | Not Cancer Driver | No | 80 | 0.132 | 45 | 4 | 0.089 | 0 |
| C12orf43_ENST00000288757 | CUSTOS | Q96C57 | Protein CUSTOS | chr12 | GO:0016055 | Not Cancer Driver | No | 39 | 0.149 | 256 | 38 | 0.148 | 0 |
| CALCOCO1 | CALCOCO1 | Q9P1Z2 | Calcium-binding and coiled-coil domain-containing protein 1 | chr12 | GO:0016055 | Not Cancer Driver | No | 88 | 0.127 | 486 | 59 | 0.121 | 0 |
| CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | GO:0016055 | Not Cancer Driver | No | 102 | 0.111 | 528 | 62 | 0.117 | 0 |
| CCN4 | CCN4 | O95388 | CCN family member 4 | chr8 | GO:0016055 | Not Cancer Driver | No | 93 | 0.253 | 20 | 8 | 0.4 | 0 |
| CCND1 | CCND1 | P24385 | G1/S-specific cyclin-D1 | chr11 | GO:0016055 | Census, Compendium | Yes | 55 | 0.186 | 31 | 25 | 0.806 | 0 |
| CCNE1 | CCNE1 | P24864 | G1/S-specific cyclin-E1 | chr19 | GO:0016055 | Census | Yes | 63 | 0.154 | 142 | 26 | 0.183 | 0 |
| CCNY | CCNY | Q8ND76 | Cyclin-Y | chr10 | GO:0016055 | Not Cancer Driver | No | 38 | 0.111 | 94 | 6 | 0.064 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0016055 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CDC73 | CDC73 | Q6P1J9 | Parafibromin | chr1 | GO:0016055 | Census, Compendium | Yes | 110 | 0.207 | 210 | 39 | 0.186 | 2 |
| CDH3 | CDH3 | P22223 | Cadherin-3 | chr16 | GO:0016055 | Not Cancer Driver | No | 87 | 0.105 | 488 | 52 | 0.107 | 2 |
| CDK14 | CDK14 | O94921 | Cyclin-dependent kinase 14 | chr7 | GO:0016055 | Not Cancer Driver | No | 93 | 0.198 | 154 | 21 | 0.136 | 0 |
| CELA1 | CELA1 | Q9UNI1 | Chymotrypsin-like elastase family member 1 | chr12 | GO:0016055 | Not Cancer Driver | No | 48 | 0.186 | 20 | 0 | 0.0 | 0 |
| CELSR1 | CELSR1 | Q9NYQ6 | Cadherin EGF LAG seven-pass G-type receptor 1 | chr22 | GO:0016055 | Not Cancer Driver | No | 390 | 0.129 | 880 | 107 | 0.122 | 4 |
| CELSR2 | CELSR2 | Q9HCU4 | Cadherin EGF LAG seven-pass G-type receptor 2 | chr1 | GO:0016055 | Not Cancer Driver | No | 348 | 0.119 | 990 | 115 | 0.116 | 0 |
| CELSR3 | CELSR3 | Q9NYQ7 | Cadherin EGF LAG seven-pass G-type receptor 3 | chr3 | GO:0016055 | Not Cancer Driver | No | 395 | 0.119 | 1315 | 167 | 0.127 | 0 |
| CHD8_ENST00000643469 | CHD8 | Q9HCK8 | Chromodomain-helicase-DNA-binding protein 8 | chr14 | GO:0016055 | Not Cancer Driver | No | 328 | 0.127 | 1411 | 148 | 0.105 | 0 |
| CPE | CPE | P16870 | Carboxypeptidase E | chr4 | GO:0016055 | Not Cancer Driver | No | 98 | 0.206 | 127 | 24 | 0.189 | 0 |
| CPZ | CPZ | Q66K79 | Carboxypeptidase Z | chr4 | GO:0016055 | Not Cancer Driver | No | 163 | 0.25 | 71 | 31 | 0.437 | 0 |
| CSNK1A1L | CSNK1A1L | Q8N752 | Casein kinase I isoform alpha-like | chr13 | GO:0016055 | Not Cancer Driver | No | 75 | 0.223 | 46 | 7 | 0.152 | 0 |
| CSNK1A1_ENST00000377843 | CSNK1A1 | P48729 | Casein kinase I isoform alpha | chr5 | GO:0016055 | Not Cancer Driver | No | 44 | 0.131 | 46 | 3 | 0.065 | 0 |
| CSNK1D | CSNK1D | P48730 | Casein kinase I isoform delta | chr17 | GO:0016055 | Not Cancer Driver | No | 59 | 0.142 | 132 | 16 | 0.121 | 2 |
| CSNK2A1_ENST00000400217 | CSNK2A1 | P68400 | Casein kinase II subunit alpha | chr20 | GO:0016055 | Not Cancer Driver | No | 71 | 0.182 | 75 | 8 | 0.107 | 4 |
| CSNK2A2 | CSNK2A2 | P19784 | Casein kinase II subunit alpha' | chr16 | GO:0016055 | Not Cancer Driver | No | 43 | 0.123 | 13 | 1 | 0.077 | 0 |
| CSNK2B_ENST00000375866 | CSNK2B | P67870 | Casein kinase II subunit beta | chr6 | GO:0016055 | Not Cancer Driver | No | 20 | 0.093 | 19 | 0 | 0.0 | 4 |
| CTHRC1 | CTHRC1 | Q96CG8 | Collagen triple helix repeat-containing protein 1 | chr8 | GO:0016055 | Not Cancer Driver | No | 31 | 0.128 | 62 | 5 | 0.081 | 0 |
| CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0016055 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
| CTNNBIP1_ENST00000377258 | CTNNBIP1 | Q9NSA3 | Beta-catenin-interacting protein 1 | chr1 | GO:0016055 | Not Cancer Driver | No | 8 | 0.099 | 64 | 7 | 0.109 | 0 |
| CTNND1 | CTNND1 | O60716 | Catenin delta-1 | chr11 | GO:0016055 | Census | Yes | 154 | 0.159 | 570 | 83 | 0.146 | 0 |
| CTNND2 | CTNND2 | Q9UQB3 | Catenin delta-2 | chr5 | GO:0016055 | Census | Yes | 386 | 0.315 | 837 | 254 | 0.303 | 0 |
| CTR9 | CTR9 | Q6PD62 | RNA polymerase-associated protein CTR9 homolog | chr11 | GO:0016055 | Not Cancer Driver | No | 164 | 0.14 | 385 | 48 | 0.125 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0016055 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0016055 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| DAAM1 | DAAM1 | Q9Y4D1 | Disheveled-associated activator of morphogenesis 1 | chr14 | GO:0016055 | Not Cancer Driver | No | 152 | 0.141 | 391 | 47 | 0.12 | 0 |
| DAAM2 | DAAM2 | Q86T65 | Disheveled-associated activator of morphogenesis 2 | chr6 | GO:0016055 | Not Cancer Driver | No | 183 | 0.171 | 272 | 55 | 0.202 | 0 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0016055 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DACT1 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | GO:0016055 | Not Cancer Driver | No | 163 | 0.195 | 598 | 127 | 0.212 | 1 |
| DACT3 | DACT3 | Q96B18 | Dapper homolog 3 | chr19 | GO:0016055 | Not Cancer Driver | No | 17 | 0.027 | 549 | 12 | 0.022 | 0 |
| DDB1 | DDB1 | Q16531 | DNA damage-binding protein 1 | chr11 | GO:0016055 | Not Cancer Driver | No | 126 | 0.111 | 50 | 8 | 0.16 | 4 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0016055 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| DDX3X_ENST00000629496 | DDX3X | O00571 | ATP-dependent RNA helicase DDX3X | chrX | GO:0016055 | Census, Compendium | Yes | 133 | 0.201 | 301 | 47 | 0.156 | 18 |
| DKK1 | DKK1 | O94907 | Dickkopf-related protein 1 | chr10 | GO:0016055 | Not Cancer Driver | No | 58 | 0.218 | 47 | 8 | 0.17 | 0 |
| DKK2 | DKK2 | Q9UBU2 | Dickkopf-related protein 2 | chr4 | GO:0016055 | Not Cancer Driver | No | 108 | 0.417 | 70 | 22 | 0.314 | 0 |
| DKK3_ENST00000326932 | DKK3 | Q9UBP4 | Dickkopf-related protein 3 | chr11 | GO:0016055 | Not Cancer Driver | No | 44 | 0.126 | 161 | 22 | 0.137 | 0 |
| DKK4 | DKK4 | Q9UBT3 | Dickkopf-related protein 4 | chr8 | GO:0016055 | Not Cancer Driver | No | 36 | 0.161 | 43 | 6 | 0.14 | 0 |
| DRAXIN | DRAXIN | Q8NBI3 | Draxin | chr1 | GO:0016055 | Not Cancer Driver | No | 61 | 0.175 | 249 | 48 | 0.193 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0016055 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0016055 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
| DVL2 | DVL2 | O14641 | Segment polarity protein dishevelled homolog DVL-2 | chr17 | GO:0016055 | Not Cancer Driver | No | 96 | 0.13 | 514 | 64 | 0.125 | 0 |
| DVL3 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0016055 | Not Cancer Driver | No | 97 | 0.135 | 437 | 58 | 0.133 | 0 |
| ETV2_ENST00000403402 | ETV2 | O00321 | ETS translocation variant 2 | chr19 | GO:0016055 | Not Cancer Driver | No | 23 | 0.067 | 227 | 15 | 0.066 | 0 |
| FAM53B | FAM53B | Q14153 | Protein FAM53B | chr10 | GO:0016055 | Not Cancer Driver | No | 46 | 0.109 | 254 | 30 | 0.118 | 0 |
| FBXW11 | FBXW11 | Q9UKB1 | F-box/WD repeat-containing protein 11 | chr5 | GO:0016055 | Not Cancer Driver | No | 75 | 0.138 | 20 | 3 | 0.15 | 7 |
| FBXW4 | FBXW4 | P57775 | F-box/WD repeat-containing protein 4 | chr10 | GO:0016055 | Not Cancer Driver | No | 36 | 0.087 | 21 | 0 | 0.0 | 0 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0016055 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FZD1 | FZD1 | Q9UP38 | Frizzled-1 | chr7 | GO:0016055 | Not Cancer Driver | No | 78 | 0.121 | 133 | 2 | 0.015 | 0 |
| FZD10 | FZD10 | Q9ULW2 | Frizzled-10 | chr12 | GO:0016055 | Not Cancer Driver | No | 148 | 0.255 | 65 | 15 | 0.231 | 0 |
| FZD2 | FZD2 | Q14332 | Frizzled-2 | chr17 | GO:0016055 | Not Cancer Driver | No | 85 | 0.15 | 47 | 5 | 0.106 | 1 |
| FZD3_ENST00000240093 | FZD3 | Q9NPG1 | Frizzled-3 | chr8 | GO:0016055 | Not Cancer Driver | No | 64 | 0.096 | 141 | 13 | 0.092 | 0 |
| FZD4 | FZD4 | Q9ULV1 | Frizzled-4 | chr11 | GO:0016055 | Not Cancer Driver | No | 57 | 0.106 | 33 | 5 | 0.152 | 19 |
| FZD6 | FZD6 | O60353 | Frizzled-6 | chr8 | GO:0016055 | Not Cancer Driver | No | 95 | 0.135 | 172 | 15 | 0.087 | 1 |
| FZD7 | FZD7 | O75084 | Frizzled-7 | chr2 | GO:0016055 | Not Cancer Driver | No | 90 | 0.157 | 22 | 2 | 0.091 | 0 |
| GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0016055 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
| GID8 | GID8 | Q9NWU2 | Glucose-induced degradation protein 8 homolog | chr20 | GO:0016055 | Not Cancer Driver | No | 30 | 0.132 | 60 | 6 | 0.1 | 0 |
| GPC4 | GPC4 | O75487 | Glypican-4 | chrX | GO:0016055 | Not Cancer Driver | No | 88 | 0.158 | 122 | 16 | 0.131 | 0 |
| GPC6 | GPC6 | Q9Y625 | Glypican-6 | chr13 | GO:0016055 | Not Cancer Driver | No | 133 | 0.24 | 140 | 36 | 0.257 | 0 |
| GRHL3 | GRHL3 | Q8TE85 | Grainyhead-like protein 3 homolog | chr1 | GO:0016055 | Not Cancer Driver | No | 83 | 0.133 | 291 | 38 | 0.131 | 3 |
| GRK5 | GRK5 | P34947 | G protein-coupled receptor kinase 5 | chr10 | GO:0016055 | Not Cancer Driver | No | 77 | 0.131 | 103 | 18 | 0.175 | 0 |
| GRK6_ENST00000355472 | GRK6 | P43250 | G protein-coupled receptor kinase 6 | chr5 | GO:0016055 | Not Cancer Driver | No | 65 | 0.113 | 68 | 10 | 0.147 | 0 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0016055 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| HBP1_ENST00000468410 | HBP1 | O60381 | HMG box-containing protein 1 | chr7 | GO:0016055 | Not Cancer Driver | No | 48 | 0.093 | 263 | 16 | 0.061 | 0 |
| HHEX | HHEX | Q03014 | Hematopoietically-expressed homeobox protein HHEX | chr10 | GO:0016055 | Not Cancer Driver | No | 23 | 0.085 | 193 | 21 | 0.109 | 0 |
| HIC1 | HIC1 | Q14526 | Hypermethylated in cancer 1 protein | chr17 | GO:0016055 | Not Cancer Driver | No | 24 | 0.033 | 361 | 6 | 0.017 | 0 |
| HMGXB4 | HMGXB4 | Q9UGU5 | HMG domain-containing protein 4 | chr22 | GO:0016055 | Not Cancer Driver | No | 68 | 0.113 | 475 | 56 | 0.118 | 0 |
| INVS | INVS | Q9Y283 | Inversin | chr9 | GO:0016055 | Not Cancer Driver | No | 125 | 0.117 | 487 | 64 | 0.131 | 2 |
| KLHL12 | KLHL12 | Q53G59 | Kelch-like protein 12 | chr1 | GO:0016055 | Not Cancer Driver | No | 65 | 0.114 | 33 | 6 | 0.182 | 0 |
| KREMEN1_ENST00000407188 | KREMEN1 | Q96MU8 | Kremen protein 1 | chr22 | GO:0016055 | Not Cancer Driver | No | 68 | 0.144 | 73 | 7 | 0.096 | 1 |
| KREMEN2 | KREMEN2 | Q8NCW0 | Kremen protein 2 | chr16 | GO:0016055 | Not Cancer Driver | No | 24 | 0.052 | 138 | 4 | 0.029 | 0 |
| LDB1 | LDB1 | Q86U70 | LIM domain-binding protein 1 | chr10 | GO:0016055 | Compendium | Yes | 56 | 0.136 | 177 | 29 | 0.164 | 0 |
| LEO1 | LEO1 | Q8WVC0 | RNA polymerase-associated protein LEO1 | chr15 | GO:0016055 | Not Cancer Driver | No | 74 | 0.111 | 611 | 69 | 0.113 | 0 |
| LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | GO:0016055 | Not Cancer Driver | No | 108 | 0.114 | 16 | 3 | 0.188 | 0 |
| LGR6 | LGR6 | Q9HBX8 | Leucine-rich repeat-containing G-protein coupled receptor 6 | chr1 | GO:0016055 | Not Cancer Driver | No | 163 | 0.169 | 101 | 16 | 0.158 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | GO:0016055 | Not Cancer Driver | No | 57 | 0.117 | 4 | 0 | 0.0 | 0 |
| LRP4 | LRP4 | O75096 | Low-density lipoprotein receptor-related protein 4 | chr11 | GO:0016055 | Not Cancer Driver | No | 233 | 0.122 | 265 | 28 | 0.106 | 11 |
| LRP6 | LRP6 | O75581 | Low-density lipoprotein receptor-related protein 6 | chr12 | GO:0016055 | Not Cancer Driver | No | 206 | 0.128 | 255 | 30 | 0.118 | 5 |
| LRRFIP2 | LRRFIP2 | Q9Y608 | Leucine-rich repeat flightless-interacting protein 2 | chr3 | GO:0016055 | Not Cancer Driver | No | 75 | 0.104 | 584 | 62 | 0.106 | 0 |
| LZTS2 | LZTS2 | Q9BRK4 | Leucine zipper putative tumor suppressor 2 | chr10 | GO:0016055 | Not Cancer Driver | No | 78 | 0.117 | 508 | 66 | 0.13 | 0 |
| MACF1_ENST00000372915 | MACF1 | Q9UPN3 | Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 | chr1 | GO:0016055 | Not Cancer Driver | No | 877 | 0.119 | 2826 | 334 | 0.118 | 4 |
| MAGI2 | MAGI2 | Q86UL8 | Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 | chr7 | GO:0016055 | Not Cancer Driver | No | 305 | 0.21 | 1086 | 201 | 0.185 | 0 |
| MARK1_ENST00000366917 | MARK1 | Q9P0L2 | Serine/threonine-protein kinase MARK1 | chr1 | GO:0016055 | Not Cancer Driver | No | 161 | 0.203 | 454 | 108 | 0.238 | 0 |
| MARK2 | MARK2 | Q7KZI7 | Serine/threonine-protein kinase MARK2 | chr11 | GO:0016055 | Compendium | Yes | 124 | 0.157 | 445 | 70 | 0.157 | 0 |
| MCC_ENST00000302475 | MCC | P23508 | Colorectal mutant cancer protein | chr5 | GO:0016055 | Not Cancer Driver | No | 136 | 0.164 | 589 | 92 | 0.156 | 0 |
| MED12 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:0016055 | Census, Compendium | Yes | 409 | 0.188 | 974 | 175 | 0.18 | 5 |
| MESD_ENST00000561312 | MESD | Q14696 | LRP chaperone MESD | chr15 | GO:0016055 | Not Cancer Driver | No | 21 | 0.09 | 150 | 14 | 0.093 | 0 |
| MITF_ENST00000448226 | MITF | O75030 | Microphthalmia-associated transcription factor | chr3 | GO:0016055 | Census | Yes | 80 | 0.152 | 408 | 69 | 0.169 | 7 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0016055 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| NDP_ENST00000642620 | NDP | Q00604 | Norrin | chrX | GO:0016055 | Not Cancer Driver | No | 14 | 0.105 | 0 | 0 | 0.0 | 60 |
| NDRG2 | NDRG2 | Q9UN36 | Protein NDRG2 | chr14 | GO:0016055 | Not Cancer Driver | No | 45 | 0.121 | 111 | 8 | 0.072 | 0 |
| NKD1 | NKD1 | Q969G9 | Protein naked cuticle homolog 1 | chr16 | GO:0016055 | Not Cancer Driver | No | 72 | 0.153 | 436 | 67 | 0.154 | 0 |
| NKD2 | NKD2 | Q969F2 | Protein naked cuticle homolog 2 | chr5 | GO:0016055 | Not Cancer Driver | No | 64 | 0.142 | 451 | 64 | 0.142 | 0 |
| NLK | NLK | Q9UBE8 | Serine/threonine-protein kinase NLK | chr17 | GO:0016055 | Not Cancer Driver | No | 54 | 0.102 | 152 | 20 | 0.132 | 0 |
| NOTUM | NOTUM | Q6P988 | Palmitoleoyl-protein carboxylesterase NOTUM | chr17 | GO:0016055 | Not Cancer Driver | No | 50 | 0.101 | 73 | 6 | 0.082 | 0 |
| NPHP3 | NPHP3 | Q7Z494 | Nephrocystin-3 | chr3 | GO:0016055 | Not Cancer Driver | No | 129 | 0.097 | 249 | 26 | 0.104 | 7 |
| NXN | NXN | Q6DKJ4 | Nucleoredoxin | chr17 | GO:0016055 | Not Cancer Driver | No | 58 | 0.133 | 37 | 2 | 0.054 | 0 |
| OTULIN | OTULIN | Q96BN8 | Ubiquitin thioesterase otulin | chr5 | GO:0016055 | Not Cancer Driver | No | 47 | 0.134 | 97 | 5 | 0.052 | 2 |
| PAF1 | PAF1 | Q8N7H5 | RNA polymerase II-associated factor 1 homolog | chr19 | GO:0016055 | Not Cancer Driver | No | 77 | 0.145 | 378 | 56 | 0.148 | 0 |
| PIAS4 | PIAS4 | Q8N2W9 | E3 SUMO-protein ligase PIAS4 | chr19 | GO:0016055 | Not Cancer Driver | No | 58 | 0.114 | 142 | 23 | 0.162 | 0 |
| PKD1 | PKD1 | P98161 | Polycystin-1 | chr16 | GO:0016055 | Not Cancer Driver | No | 393 | 0.091 | 690 | 66 | 0.096 | 92 |
| PKD2 | PKD2 | Q13563 | Polycystin-2 | chr4 | GO:0016055 | Not Cancer Driver | No | 113 | 0.117 | 375 | 35 | 0.093 | 10 |
| PLCG2 | PLCG2 | P16885 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 | chr16 | GO:0016055 | Not Cancer Driver | No | 248 | 0.196 | 142 | 30 | 0.211 | 1 |
| PLPP3 | PLPP3 | O14495 | Phospholipid phosphatase 3 | chr1 | GO:0016055 | Not Cancer Driver | No | 48 | 0.154 | 10 | 1 | 0.1 | 0 |
| PORCN | PORCN | Q9H237 | Protein-serine O-palmitoleoyltransferase porcupine | chrX | GO:0016055 | Not Cancer Driver | No | 77 | 0.167 | 0 | 0 | 0.0 | 15 |
| PRICKLE1_ENST00000640055 | PRICKLE1 | Q96MT3 | Prickle-like protein 1 | chr12 | GO:0016055 | Not Cancer Driver | No | 146 | 0.176 | 485 | 91 | 0.188 | 3 |
| PRICKLE2 | PRICKLE2 | Q7Z3G6 | Prickle-like protein 2 | chr3 | GO:0016055 | Not Cancer Driver | No | 131 | 0.155 | 502 | 80 | 0.159 | 0 |
| PRKAA1_ENST00000397128 | PRKAA1 | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | chr5 | GO:0016055 | Not Cancer Driver | No | 72 | 0.129 | 124 | 17 | 0.137 | 0 |
| PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0016055 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
| PTK7_ENST00000230419 | PTK7 | Q13308 | Inactive tyrosine-protein kinase 7 | chr6 | GO:0016055 | Not Cancer Driver | No | 153 | 0.143 | 359 | 58 | 0.162 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0016055 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | GO:0016055 | Not Cancer Driver | No | 24 | 0.125 | 0 | 0 | 0.0 | 4 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0016055 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RNF138 | RNF138 | Q8WVD3 | E3 ubiquitin-protein ligase RNF138 | chr18 | GO:0016055 | Not Cancer Driver | No | 44 | 0.18 | 34 | 6 | 0.176 | 0 |
| RNF146 | RNF146 | Q9NTX7 | E3 ubiquitin-protein ligase RNF146 | chr6 | GO:0016055 | Not Cancer Driver | No | 37 | 0.103 | 206 | 24 | 0.117 | 0 |
| RNF43_ENST00000577716 | RNF43 | Q68DV7 | E3 ubiquitin-protein ligase RNF43 | chr17 | GO:0016055 | Census, Compendium | Yes | 121 | 0.155 | 437 | 54 | 0.124 | 0 |
| ROR1 | ROR1 | Q01973 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | chr1 | GO:0016055 | Not Cancer Driver | No | 144 | 0.154 | 280 | 43 | 0.154 | 1 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0016055 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| RSPO1_ENST00000401068 | RSPO1 | Q2MKA7 | R-spondin-1 | chr1 | GO:0016055 | Not Cancer Driver | No | 59 | 0.224 | 82 | 16 | 0.195 | 0 |
| RSPO2 | RSPO2 | Q6UXX9 | R-spondin-2 | chr8 | GO:0016055 | Census | Yes | 96 | 0.395 | 41 | 10 | 0.244 | 1 |
| RSPO3 | RSPO3 | Q9BXY4 | R-spondin-3 | chr6 | GO:0016055 | Census | Yes | 44 | 0.162 | 100 | 12 | 0.12 | 0 |
| RSPO4 | RSPO4 | Q2I0M5 | R-spondin-4 | chr20 | GO:0016055 | Not Cancer Driver | No | 34 | 0.145 | 52 | 7 | 0.135 | 4 |
| RTF1 | RTF1 | Q92541 | RNA polymerase-associated protein RTF1 homolog | chr15 | GO:0016055 | Not Cancer Driver | No | 83 | 0.117 | 568 | 67 | 0.118 | 0 |
| RYK_ENST00000623711 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:0016055 | Not Cancer Driver | No | 55 | 0.091 | 85 | 4 | 0.047 | 0 |
| SENP2 | SENP2 | Q9HC62 | Sentrin-specific protease 2 | chr3 | GO:0016055 | Not Cancer Driver | No | 73 | 0.124 | 285 | 38 | 0.133 | 0 |
| SFRP1 | SFRP1 | Q8N474 | Secreted frizzled-related protein 1 | chr8 | GO:0016055 | Not Cancer Driver | No | 40 | 0.127 | 39 | 7 | 0.179 | 0 |
| SFRP2 | SFRP2 | Q96HF1 | Secreted frizzled-related protein 2 | chr4 | GO:0016055 | Not Cancer Driver | No | 47 | 0.159 | 1 | 0 | 0.0 | 0 |
| SHISA6_ENST00000409168 | SHISA6 | Q6ZSJ9 | Protein shisa-6 | chr17 | GO:0016055 | Not Cancer Driver | No | 29 | 0.058 | 330 | 22 | 0.067 | 0 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0016055 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| SMURF1 | SMURF1 | Q9HCE7 | E3 ubiquitin-protein ligase SMURF1 | chr7 | GO:0016055 | Not Cancer Driver | No | 89 | 0.118 | 256 | 31 | 0.121 | 0 |
| SMURF2 | SMURF2 | Q9HAU4 | E3 ubiquitin-protein ligase SMURF2 | chr17 | GO:0016055 | Not Cancer Driver | No | 87 | 0.116 | 242 | 28 | 0.116 | 0 |
| SOST | SOST | Q9BQB4 | Sclerostin | chr17 | GO:0016055 | Not Cancer Driver | No | 30 | 0.141 | 90 | 12 | 0.133 | 3 |
| SOSTDC1 | SOSTDC1 | Q6X4U4 | Sclerostin domain-containing protein 1 | chr7 | GO:0016055 | Not Cancer Driver | No | 22 | 0.107 | 72 | 3 | 0.042 | 0 |
| SOX17 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | GO:0016055 | Compendium | Yes | 81 | 0.196 | 378 | 59 | 0.156 | 2 |
| SPIN1 | SPIN1 | Q9Y657 | Spindlin-1 | chr9 | GO:0016055 | Not Cancer Driver | No | 31 | 0.118 | 132 | 18 | 0.136 | 0 |
| STRN | STRN | O43815 | Striatin | chr2 | GO:0016055 | Census, Compendium | Yes | 97 | 0.124 | 348 | 43 | 0.124 | 0 |
| TAX1BP3 | TAX1BP3 | O14907 | Tax1-binding protein 3 | chr17 | GO:0016055 | Not Cancer Driver | No | 16 | 0.129 | 51 | 8 | 0.157 | 0 |
| TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0016055 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
| TGFB1I1 | TGFB1I1 | O43294 | Transforming growth factor beta-1-induced transcript 1 protein | chr16 | GO:0016055 | Not Cancer Driver | No | 61 | 0.132 | 219 | 34 | 0.155 | 0 |
| TIAM1 | TIAM1 | Q13009 | Rho guanine nucleotide exchange factor TIAM1 | chr21 | GO:0016055 | Not Cancer Driver | No | 370 | 0.233 | 810 | 194 | 0.24 | 0 |
| TLE1 | TLE1 | Q04724 | Transducin-like enhancer protein 1 | chr9 | GO:0016055 | Not Cancer Driver | No | 111 | 0.144 | 381 | 53 | 0.139 | 0 |
| TLE2_ENST00000262953 | TLE2 | Q04725 | Transducin-like enhancer protein 2 | chr19 | GO:0016055 | Not Cancer Driver | No | 78 | 0.105 | 283 | 29 | 0.102 | 0 |
| TLE3 | TLE3 | Q04726 | Transducin-like enhancer protein 3 | chr15 | GO:0016055 | Not Cancer Driver | No | 87 | 0.113 | 381 | 50 | 0.131 | 0 |
| TLE4_ENST00000376552 | TLE4 | Q04727 | Transducin-like enhancer protein 4 | chr9 | GO:0016055 | Not Cancer Driver | No | 172 | 0.223 | 381 | 92 | 0.241 | 0 |
| TMEM131L_ENST00000409663 | TMEM131L | A2VDJ0 | Transmembrane protein 131-like | chr4 | GO:0016055 | Not Cancer Driver | No | 188 | 0.117 | 448 | 47 | 0.105 | 0 |
| TMEM170B | TMEM170B | Q5T4T1 | Transmembrane protein 170B | chr6 | GO:0016055 | Not Cancer Driver | No | 17 | 0.129 | 0 | 0 | 0.0 | 0 |
| TMEM198_ENST00000373883 | TMEM198 | Q66K66 | Transmembrane protein 198 | chr2 | GO:0016055 | Not Cancer Driver | No | 58 | 0.161 | 102 | 22 | 0.216 | 0 |
| TMEM88 | TMEM88 | Q6PEY1 | Transmembrane protein 88 | chr17 | GO:0016055 | Not Cancer Driver | No | 21 | 0.132 | 18 | 1 | 0.056 | 0 |
| TNIK | TNIK | Q9UKE5 | TRAF2 and NCK-interacting protein kinase | chr3 | GO:0016055 | Not Cancer Driver | No | 254 | 0.187 | 781 | 156 | 0.2 | 0 |
| TNKS | TNKS | O95271 | Poly [ADP-ribose] polymerase tankyrase-1 | chr8 | GO:0016055 | Not Cancer Driver | No | 163 | 0.123 | 480 | 59 | 0.123 | 0 |
| TNKS2 | TNKS2 | Q9H2K2 | Poly [ADP-ribose] polymerase tankyrase-2 | chr10 | GO:0016055 | Not Cancer Driver | No | 117 | 0.1 | 255 | 24 | 0.094 | 0 |
| TRABD2A | TRABD2A | Q86V40 | Metalloprotease TIKI1 | chr2 | GO:0016055 | Not Cancer Driver | No | 80 | 0.158 | 132 | 35 | 0.265 | 0 |
| TRABD2B | TRABD2B | A6NFA1 | Metalloprotease TIKI2 | chr1 | GO:0016055 | Not Cancer Driver | No | 3 | 0.006 | 211 | 1 | 0.005 | 0 |
| UBAC2 | UBAC2 | Q8NBM4 | Ubiquitin-associated domain-containing protein 2 | chr13 | GO:0016055 | Not Cancer Driver | No | 33 | 0.096 | 57 | 9 | 0.158 | 0 |
| USP34 | USP34 | Q70CQ2 | Ubiquitin carboxyl-terminal hydrolase 34 | chr2 | GO:0016055 | Not Cancer Driver | No | 436 | 0.123 | 725 | 90 | 0.124 | 0 |
| VANGL1 | VANGL1 | Q8TAA9 | Vang-like protein 1 | chr1 | GO:0016055 | Not Cancer Driver | No | 72 | 0.137 | 140 | 15 | 0.107 | 3 |
| VANGL2 | VANGL2 | Q9ULK5 | Vang-like protein 2 | chr1 | GO:0016055 | Not Cancer Driver | No | 122 | 0.234 | 150 | 37 | 0.247 | 3 |
| VAX2 | VAX2 | Q9UIW0 | Ventral anterior homeobox 2 | chr2 | GO:0016055 | Not Cancer Driver | No | 34 | 0.117 | 210 | 22 | 0.105 | 0 |
| VPS35 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | GO:0016055 | Not Cancer Driver | No | 68 | 0.085 | 99 | 9 | 0.091 | 1 |
| WDR61 | WDR61 | Q9GZS3 | WD repeat-containing protein 61 | chr15 | GO:0016055 | Not Cancer Driver | No | 25 | 0.082 | 7 | 1 | 0.143 | 0 |
| WIF1 | WIF1 | Q9Y5W5 | Wnt inhibitory factor 1 | chr12 | GO:0016055 | Census | Yes | 74 | 0.195 | 30 | 3 | 0.1 | 0 |
| WLS_ENST00000262348 | WLS | Q5T9L3 | Protein wntless homolog | chr1 | GO:0016055 | Not Cancer Driver | No | 71 | 0.131 | 14 | 3 | 0.214 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0016055 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| WNT11 | WNT11 | O96014 | Protein Wnt-11 | chr11 | GO:0016055 | Not Cancer Driver | No | 55 | 0.155 | 59 | 4 | 0.068 | 0 |
| WNT2 | WNT2 | P09544 | Protein Wnt-2 | chr7 | GO:0016055 | Not Cancer Driver | No | 85 | 0.236 | 11 | 3 | 0.273 | 0 |
| WNT3 | WNT3 | P56703 | Proto-oncogene Wnt-3 | chr17 | GO:0016055 | Not Cancer Driver | No | 56 | 0.158 | 34 | 7 | 0.206 | 0 |
| WNT3A | WNT3A | P56704 | Protein Wnt-3a | chr1 | GO:0016055 | Not Cancer Driver | No | 77 | 0.219 | 37 | 5 | 0.135 | 0 |
| WNT4 | WNT4 | P56705 | Protein Wnt-4 | chr1 | GO:0016055 | Not Cancer Driver | No | 30 | 0.085 | 39 | 4 | 0.103 | 4 |
| WNT5A_ENST00000474267 | WNT5A | P41221 | Protein Wnt-5a | chr3 | GO:0016055 | Not Cancer Driver | No | 66 | 0.174 | 0 | 0 | 0.0 | 2 |
| WNT7A | WNT7A | O00755 | Protein Wnt-7a | chr3 | GO:0016055 | Not Cancer Driver | No | 93 | 0.266 | 18 | 9 | 0.5 | 4 |
| WNT7B | WNT7B | P56706 | Protein Wnt-7b | chr22 | GO:0016055 | Not Cancer Driver | No | 55 | 0.158 | 11 | 1 | 0.091 | 0 |
| WNT8A_ENST00000398754 | WNT8A | Q9H1J5 | Protein Wnt-8a | chr5 | GO:0016055 | Not Cancer Driver | No | 50 | 0.142 | 3 | 0 | 0.0 | 0 |
| WNT9B | WNT9B | O14905 | Protein Wnt-9b | chr17 | GO:0016055 | Not Cancer Driver | No | 47 | 0.132 | 11 | 4 | 0.364 | 0 |
| WWOX | WWOX | Q9NZC7 | WW domain-containing oxidoreductase | chr16 | GO:0016055 | Not Cancer Driver | No | 79 | 0.191 | 108 | 9 | 0.083 | 3 |
| XIAP_ENST00000434753 | XIAP | P98170 | E3 ubiquitin-protein ligase XIAP | chrX | GO:0016055 | Not Cancer Driver | No | 89 | 0.179 | 55 | 6 | 0.109 | 0 |
| ZBED3 | ZBED3 | Q96IU2 | Zinc finger BED domain-containing protein 3 | chr5 | GO:0016055 | Not Cancer Driver | No | 2 | 0.009 | 229 | 2 | 0.009 | 0 |
| ZBTB33 | ZBTB33 | Q86T24 | Transcriptional regulator Kaiso | chrX | GO:0016055 | Not Cancer Driver | No | 110 | 0.164 | 352 | 58 | 0.165 | 0 |
| ZNRF3 | ZNRF3 | Q9ULT6 | E3 ubiquitin-protein ligase ZNRF3 | chr22 | GO:0016055 | Census, Compendium | Yes | 94 | 0.1 | 510 | 51 | 0.1 | 0 |
| ZRANB1 | ZRANB1 | Q9UGI0 | Ubiquitin thioesterase ZRANB1 | chr10 | GO:0016055 | Not Cancer Driver | No | 87 | 0.123 | 158 | 25 | 0.158 | 0 |