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Total number of protein in "GO:0015267" GO term:  355

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0015267 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABCC9_ENST00000261201 ABCC9 O60706 ATP-binding cassette sub-family C member 9 chr12 GO:0015267 Not Cancer Driver No 368 0.238 132 30 0.227 15
ANO1 ANO1 Q5XXA6 Anoctamin-1 chr11 GO:0015267 Not Cancer Driver No 155 0.157 168 14 0.083 0
ANO10 ANO10 Q9NW15 Anoctamin-10 chr3 GO:0015267 Not Cancer Driver No 65 0.098 18 2 0.111 1
ANO2_ENST00000327087 ANO2 Q9NQ90 Anoctamin-2 chr12 GO:0015267 Not Cancer Driver No 239 0.238 277 48 0.173 0
ANO3 ANO3 Q9BYT9 Anoctamin-3 chr11 GO:0015267 Not Cancer Driver No 197 0.201 102 20 0.196 4
ANO4 ANO4 Q32M45 Anoctamin-4 chr12 GO:0015267 Not Cancer Driver No 320 0.335 133 35 0.263 0
ANO5 ANO5 Q75V66 Anoctamin-5 chr11 GO:0015267 Not Cancer Driver No 227 0.249 42 17 0.405 3
ANO6_ENST00000320560 ANO6 Q4KMQ2 Anoctamin-6 chr12 GO:0015267 Not Cancer Driver No 134 0.147 80 11 0.138 0
ANO7 ANO7 Q6IWH7 Anoctamin-7 chr2 GO:0015267 Not Cancer Driver No 144 0.154 147 32 0.218 0
ANO8 ANO8 Q9HCE9 Anoctamin-8 chr19 GO:0015267 Not Cancer Driver No 105 0.085 606 44 0.073 0
ANO9 ANO9 A1A5B4 Anoctamin-9 chr11 GO:0015267 Not Cancer Driver No 108 0.138 64 6 0.094 0
AP000311.1 AP000311.1 H7C0C1 ATP synthase subunit O, mitochondrial (Fragment) chr21 GO:0015267 Not Cancer Driver No 27 0.112 27 5 0.185 0
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0015267 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP10 AQP10 Q96PS8 Aquaporin-10 chr1 GO:0015267 Not Cancer Driver No 73 0.243 15 1 0.067 0
AQP11 AQP11 Q8NBQ7 Aquaporin-11 chr11 GO:0015267 Not Cancer Driver No 23 0.085 0 0 0.0 0
AQP12A_ENST00000337801 AQP12A Q8IXF9 Aquaporin-12A chr2 GO:0015267 Not Cancer Driver No 42 0.142 37 0 0.0 0
AQP12B_ENST00000621682 AQP12B A6NM10 Aquaporin-12B chr2 GO:0015267 Not Cancer Driver No 46 0.156 37 0 0.0 0
AQP2 AQP2 P41181 Aquaporin-2 chr12 GO:0015267 Not Cancer Driver No 52 0.192 31 3 0.097 28
AQP3 AQP3 Q92482 Aquaporin-3 chr9 GO:0015267 Not Cancer Driver No 34 0.116 12 0 0.0 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0015267 Not Cancer Driver No 50 0.155 30 9 0.3 0
AQP5 AQP5 P55064 Aquaporin-5 chr12 GO:0015267 Not Cancer Driver No 31 0.117 21 2 0.095 5
AQP6_ENST00000315520 AQP6 Q13520 Aquaporin-6 chr12 GO:0015267 Not Cancer Driver No 48 0.17 22 4 0.182 0
AQP7 AQP7 O14520 Aquaporin-7 chr9 GO:0015267 Not Cancer Driver No 61 0.178 29 2 0.069 0
AQP8 AQP8 O94778 Aquaporin-8 chr16 GO:0015267 Not Cancer Driver No 49 0.188 0 0 0.0 0
AQP9 AQP9 O43315 Aquaporin-9 chr15 GO:0015267 Not Cancer Driver No 75 0.254 12 0 0.0 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0015267 Not Cancer Driver No 69 0.131 17 2 0.118 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0015267 Not Cancer Driver No 101 0.197 49 1 0.02 0
ASIC3_ENST00000349064 ASIC3 Q9UHC3 Acid-sensing ion channel 3 chr7 GO:0015267 Not Cancer Driver No 83 0.156 126 23 0.183 0
ASIC5 ASIC5 Q9NY37 Acid-sensing ion channel 5 chr4 GO:0015267 Not Cancer Driver No 112 0.222 12 4 0.333 0
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0015267 Not Cancer Driver No 66 0.119 23 5 0.217 2
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0015267 Not Cancer Driver No 60 0.113 85 8 0.094 0
ATP5F1C ATP5F1C P36542 ATP synthase subunit gamma, mitochondrial chr10 GO:0015267 Not Cancer Driver No 39 0.131 11 0 0.0 0
ATP5F1D_ENST00000591660 ATP5F1D P30049 ATP synthase subunit delta, mitochondrial chr19 GO:0015267 Not Cancer Driver No 7 0.042 5 1 0.2 2
ATP5F1E_ENST00000395663 ATP5F1E P56381 ATP synthase subunit epsilon, mitochondrial chr20 GO:0015267 Not Cancer Driver No 3 0.059 1 0 0.0 1
ATP5ME ATP5ME P56385 ATP synthase subunit e, mitochondrial chr4 GO:0015267 Not Cancer Driver No 6 0.087 18 2 0.111 0
ATP5MF ATP5MF P56134 ATP synthase subunit f, mitochondrial chr7 GO:0015267 Not Cancer Driver No 22 0.234 0 0 0.0 0
ATP5MG ATP5MG O75964 ATP synthase subunit g, mitochondrial chr11 GO:0015267 Not Cancer Driver No 16 0.155 0 0 0.0 0
ATP5PB ATP5PB P24539 ATP synthase F(0) complex subunit B1, mitochondrial chr1 GO:0015267 Not Cancer Driver No 37 0.145 2 0 0.0 0
ATP5PD ATP5PD O75947 ATP synthase subunit d, mitochondrial chr17 GO:0015267 Not Cancer Driver No 12 0.075 15 0 0.0 0
ATP5PF_ENST00000400090 ATP5PF P18859 ATP synthase-coupling factor 6, mitochondrial chr21 GO:0015267 Not Cancer Driver No 14 0.13 15 1 0.067 0
ATP5PO ATP5PO P48047 ATP synthase subunit O, mitochondrial chr21 GO:0015267 Not Cancer Driver No 19 0.089 9 2 0.222 0
ATP6V0C ATP6V0C P27449 V-type proton ATPase 16 kDa proteolipid subunit c chr16 GO:0015267 Not Cancer Driver No 19 0.123 1 0 0.0 0
ATP6V1A ATP6V1A P38606 V-type proton ATPase catalytic subunit A chr3 GO:0015267 Not Cancer Driver No 86 0.139 31 2 0.065 4
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0015267 Census Yes 30 0.156 39 2 0.051 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0015267 Census, Compendium Yes 24 0.1 72 5 0.069 0
BEST1_ENST00000378043 BEST1 O76090 Bestrophin-1 chr11 GO:0015267 Not Cancer Driver No 47 0.08 229 18 0.079 108
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0015267 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA1B CACNA1B Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B chr9 GO:0015267 Not Cancer Driver No 416 0.178 917 115 0.125 0
CACNA1C CACNA1C Q13936 Voltage-dependent L-type calcium channel subunit alpha-1C chr12 GO:0015267 Not Cancer Driver No 455 0.205 744 146 0.196 14
CACNA1D_ENST00000350061 CACNA1D Q01668 Voltage-dependent L-type calcium channel subunit alpha-1D chr3 GO:0015267 Census, Compendium Yes 342 0.158 736 126 0.171 2
CACNA1E_ENST00000621551 CACNA1E Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E chr1 GO:0015267 Not Cancer Driver No 778 0.336 917 339 0.37 14
CACNA1F CACNA1F O60840 Voltage-dependent L-type calcium channel subunit alpha-1F chrX GO:0015267 Not Cancer Driver No 284 0.144 530 78 0.147 20
CACNA1G CACNA1G O43497 Voltage-dependent T-type calcium channel subunit alpha-1G chr17 GO:0015267 Not Cancer Driver No 367 0.154 1022 149 0.146 3
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 GO:0015267 Not Cancer Driver No 323 0.137 1045 141 0.135 18
CACNA1I CACNA1I Q9P0X4 Voltage-dependent T-type calcium channel subunit alpha-1I chr22 GO:0015267 Not Cancer Driver No 272 0.122 870 73 0.084 0
CACNA1S CACNA1S Q13698 Voltage-dependent L-type calcium channel subunit alpha-1S chr1 GO:0015267 Not Cancer Driver No 389 0.208 382 76 0.199 6
CACNA2D1_ENST00000356253 CACNA2D1 P54289 Voltage-dependent calcium channel subunit alpha-2/delta-1 chr7 GO:0015267 Not Cancer Driver No 277 0.251 99 25 0.253 0
CACNB1 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:0015267 Not Cancer Driver No 75 0.125 396 47 0.119 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0015267 Not Cancer Driver No 155 0.235 478 106 0.222 0
CACNB3 CACNB3 P54284 Voltage-dependent L-type calcium channel subunit beta-3 chr12 GO:0015267 Not Cancer Driver No 58 0.12 258 30 0.116 0
CACNB4 CACNB4 O00305 Voltage-dependent L-type calcium channel subunit beta-4 chr2 GO:0015267 Not Cancer Driver No 82 0.158 295 49 0.166 1
CCDC51 CCDC51 Q96ER9 Mitochondrial potassium channel chr3 GO:0015267 Not Cancer Driver No 51 0.124 137 21 0.153 0
CCT8L2 CCT8L2 Q96SF2 T-complex protein 1 subunit theta-like 2 chr22 GO:0015267 Not Cancer Driver No 216 0.388 104 46 0.442 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0015267 Not Cancer Driver No 48 0.164 5 1 0.2 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0015267 Not Cancer Driver No 287 0.194 145 18 0.124 151
CHRFAM7A CHRFAM7A Q494W8 CHRNA7-FAM7A fusion protein chr15 GO:0015267 Not Cancer Driver No 40 0.097 18 0 0.0 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:0015267 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA1_ENST00000348749 CHRNA1 P02708 Acetylcholine receptor subunit alpha chr2 GO:0015267 Not Cancer Driver No 86 0.188 9 1 0.111 12
CHRNA2 CHRNA2 Q15822 Neuronal acetylcholine receptor subunit alpha-2 chr8 GO:0015267 Not Cancer Driver No 85 0.161 33 5 0.152 1
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0015267 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 GO:0015267 Not Cancer Driver No 144 0.23 186 33 0.177 2
CHRNA5 CHRNA5 P30532 Neuronal acetylcholine receptor subunit alpha-5 chr15 GO:0015267 Not Cancer Driver No 63 0.135 24 3 0.125 0
CHRNA6 CHRNA6 Q15825 Neuronal acetylcholine receptor subunit alpha-6 chr8 GO:0015267 Not Cancer Driver No 101 0.204 33 6 0.182 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0015267 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:0015267 Not Cancer Driver No 76 0.159 23 6 0.261 0
CHRNB1 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 GO:0015267 Not Cancer Driver No 62 0.124 45 9 0.2 3
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0015267 Not Cancer Driver No 92 0.183 23 2 0.087 2
CHRNB3 CHRNB3 Q05901 Neuronal acetylcholine receptor subunit beta-3 chr8 GO:0015267 Not Cancer Driver No 125 0.273 4 1 0.25 0
CHRNB4 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 GO:0015267 Not Cancer Driver No 98 0.197 30 6 0.2 0
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 GO:0015267 Not Cancer Driver No 110 0.213 71 19 0.268 7
CHRNE CHRNE Q04844 Acetylcholine receptor subunit epsilon chr17 GO:0015267 Not Cancer Driver No 52 0.105 37 3 0.081 13
CHRNG CHRNG P07510 Acetylcholine receptor subunit gamma chr2 GO:0015267 Not Cancer Driver No 78 0.151 8 1 0.125 4
CLCA1 CLCA1 A8K7I4 Calcium-activated chloride channel regulator 1 chr1 GO:0015267 Not Cancer Driver No 144 0.158 212 22 0.104 0
CLCA2 CLCA2 Q9UQC9 Calcium-activated chloride channel regulator 2 chr1 GO:0015267 Not Cancer Driver No 131 0.139 222 35 0.158 0
CLCA4 CLCA4 Q14CN2 Calcium-activated chloride channel regulator 4 chr1 GO:0015267 Not Cancer Driver No 191 0.208 192 41 0.214 0
CLCN1 CLCN1 P35523 Chloride channel protein 1 chr7 GO:0015267 Not Cancer Driver No 224 0.227 355 77 0.217 54
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 GO:0015267 Not Cancer Driver No 124 0.138 224 38 0.17 8
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0015267 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLCN4 CLCN4 P51793 H(+)/Cl(-) exchange transporter 4 chrX GO:0015267 Not Cancer Driver No 118 0.155 62 13 0.21 11
CLCN5 CLCN5 P51795 H(+)/Cl(-) exchange transporter 5 chrX GO:0015267 Not Cancer Driver No 138 0.169 81 6 0.074 32
CLCN6 CLCN6 P51797 H(+)/Cl(-) exchange transporter 6 chr1 GO:0015267 Not Cancer Driver No 123 0.142 109 24 0.22 1
CLCN7 CLCN7 P51798 H(+)/Cl(-) exchange transporter 7 chr16 GO:0015267 Not Cancer Driver No 102 0.127 94 7 0.074 29
CLCNKA CLCNKA P51800 Chloride channel protein ClC-Ka chr1 GO:0015267 Not Cancer Driver No 92 0.134 35 3 0.086 1
CLCNKB CLCNKB P51801 Chloride channel protein ClC-Kb chr1 GO:0015267 Not Cancer Driver No 104 0.151 23 9 0.391 5
CNGA1_ENST00000420489 CNGA1 P29973 cGMP-gated cation channel alpha-1 chr4 GO:0015267 Not Cancer Driver No 136 0.198 185 37 0.2 1
CNGA2 CNGA2 Q16280 Cyclic nucleotide-gated olfactory channel chrX GO:0015267 Not Cancer Driver No 159 0.239 161 33 0.205 0
CNGA3 CNGA3 Q16281 Cyclic nucleotide-gated cation channel alpha-3 chr2 GO:0015267 Not Cancer Driver No 183 0.264 217 67 0.309 53
CNGA4 CNGA4 Q8IV77 Cyclic nucleotide-gated cation channel alpha-4 chr11 GO:0015267 Not Cancer Driver No 132 0.23 79 13 0.165 0
CNGB1 CNGB1 Q14028 Cyclic nucleotide-gated cation channel beta-1 chr16 GO:0015267 Not Cancer Driver No 206 0.165 789 120 0.152 1
CNGB3 CNGB3 Q9NQW8 Cyclic nucleotide-gated cation channel beta-3 chr8 GO:0015267 Not Cancer Driver No 244 0.302 338 123 0.364 8
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0015267 Not Cancer Driver No 129 0.273 9 1 0.111 0
FAM155A NALF1 B1AL88 NALCN channel auxiliary factor 1 chr13 GO:0015267 Not Cancer Driver No 121 0.264 162 51 0.315 0
FAM155B NALF2 O75949 NALCN channel auxiliary factor 2 chrX GO:0015267 Not Cancer Driver No 56 0.119 160 26 0.163 0
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0015267 Not Cancer Driver No 10 0.093 58 4 0.069 0
GABRA1_ENST00000638112 GABRA1 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 chr5 GO:0015267 Not Cancer Driver No 175 0.384 58 31 0.534 6
GABRA2_ENST00000356504 GABRA2 P47869 Gamma-aminobutyric acid receptor subunit alpha-2 chr4 GO:0015267 Not Cancer Driver No 194 0.43 26 13 0.5 5
GABRA3_ENST00000535043 GABRA3 P34903 Gamma-aminobutyric acid receptor subunit alpha-3 chrX GO:0015267 Not Cancer Driver No 136 0.276 47 10 0.213 0
GABRA4 GABRA4 P48169 Gamma-aminobutyric acid receptor subunit alpha-4 chr4 GO:0015267 Not Cancer Driver No 191 0.345 179 82 0.458 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0015267 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRA6 GABRA6 Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 chr5 GO:0015267 Not Cancer Driver No 186 0.411 7 2 0.286 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0015267 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0015267 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0015267 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRD GABRD O14764 Gamma-aminobutyric acid receptor subunit delta chr1 GO:0015267 Not Cancer Driver No 71 0.157 19 5 0.263 1
GABRE GABRE P78334 Gamma-aminobutyric acid receptor subunit epsilon chrX GO:0015267 Not Cancer Driver No 133 0.263 73 19 0.26 0
GABRG1 GABRG1 Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 chr4 GO:0015267 Not Cancer Driver No 216 0.465 7 3 0.429 0
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0015267 Not Cancer Driver No 188 0.403 19 13 0.684 11
GABRG3 GABRG3 Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 chr15 GO:0015267 Not Cancer Driver No 137 0.293 12 5 0.417 0
GABRP_ENST00000265294 GABRP O00591 Gamma-aminobutyric acid receptor subunit pi chr5 GO:0015267 Not Cancer Driver No 81 0.184 0 0 0.0 0
GABRQ GABRQ Q9UN88 Gamma-aminobutyric acid receptor subunit theta chrX GO:0015267 Not Cancer Driver No 158 0.25 175 58 0.331 0
GABRR1 GABRR1 P24046 Gamma-aminobutyric acid receptor subunit rho-1 chr6 GO:0015267 Not Cancer Driver No 93 0.194 99 26 0.263 0
GABRR2 GABRR2 P28476 Gamma-aminobutyric acid receptor subunit rho-2 chr6 GO:0015267 Not Cancer Driver No 64 0.138 8 0 0.0 0
GABRR3 GABRR3 A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3 chr3 GO:0015267 Not Cancer Driver No 76 0.163 30 7 0.233 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0015267 Not Cancer Driver No 86 0.225 110 26 0.236 50
GJA10 GJA10 Q969M2 Gap junction alpha-10 protein chr6 GO:0015267 Not Cancer Driver No 135 0.249 210 42 0.2 0
GJA3 GJA3 Q9Y6H8 Gap junction alpha-3 protein chr13 GO:0015267 Not Cancer Driver No 37 0.085 211 13 0.062 20
GJA4 GJA4 P35212 Gap junction alpha-4 protein chr1 GO:0015267 Not Cancer Driver No 48 0.144 74 14 0.189 0
GJA5 GJA5 P36382 Gap junction alpha-5 protein chr1 GO:0015267 Not Cancer Driver No 74 0.207 92 21 0.228 5
GJA8 GJA8 P48165 Gap junction alpha-8 protein chr1 GO:0015267 Not Cancer Driver No 139 0.321 173 56 0.324 9
GJA9_ENST00000357771 GJA9 P57773 Gap junction alpha-9 protein chr1 GO:0015267 Not Cancer Driver No 64 0.124 218 25 0.115 0
GJB1_ENST00000647424 GJB1 P08034 Gap junction beta-1 protein chrX GO:0015267 Not Cancer Driver No 34 0.12 23 7 0.304 189
GJB2_ENST00000382848 GJB2 P29033 Gap junction beta-2 protein chr13 GO:0015267 Not Cancer Driver No 34 0.15 0 0 0.0 46
GJB3 GJB3 O75712 Gap junction beta-3 protein chr1 GO:0015267 Not Cancer Driver No 48 0.178 13 0 0.0 6
GJB4 GJB4 Q9NTQ9 Gap junction beta-4 protein chr1 GO:0015267 Not Cancer Driver No 69 0.259 7 1 0.143 5
GJB5 GJB5 O95377 Gap junction beta-5 protein chr1 GO:0015267 Not Cancer Driver No 38 0.139 8 5 0.625 0
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0015267 Not Cancer Driver No 42 0.161 12 4 0.333 4
GJB7 GJB7 Q6PEY0 Gap junction beta-7 protein chr6 GO:0015267 Not Cancer Driver No 30 0.135 0 0 0.0 0
GJC1_ENST00000590758 GJC1 P36383 Gap junction gamma-1 protein chr17 GO:0015267 Not Cancer Driver No 63 0.159 150 30 0.2 0
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0015267 Not Cancer Driver No 33 0.075 225 10 0.044 6
GJC3 GJC3 Q8NFK1 Gap junction gamma-3 protein chr7 GO:0015267 Not Cancer Driver No 32 0.115 42 14 0.333 0
GJD2 GJD2 Q9UKL4 Gap junction delta-2 protein chr15 GO:0015267 Not Cancer Driver No 86 0.268 58 17 0.293 0
GJD3 GJD3 Q8N144 Gap junction delta-3 protein chr17 GO:0015267 Not Cancer Driver No 5 0.017 79 0 0.0 0
GJD4 GJD4 Q96KN9 Gap junction delta-4 protein chr10 GO:0015267 Not Cancer Driver No 44 0.119 164 8 0.049 0
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0015267 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRA2 GLRA2 P23416 Glycine receptor subunit alpha-2 chrX GO:0015267 Not Cancer Driver No 106 0.235 58 14 0.241 0
GLRA3 GLRA3 O75311 Glycine receptor subunit alpha-3 chr4 GO:0015267 Not Cancer Driver No 132 0.284 32 11 0.344 0
GLRB GLRB P48167 Glycine receptor subunit beta chr4 GO:0015267 Not Cancer Driver No 112 0.225 66 12 0.182 4
GPR89A GPR89A B7ZAQ6 Golgi pH regulator A chr1 GO:0015267 Not Cancer Driver No 22 0.048 1 0 0.0 0
GPR89B GPR89B P0CG08 Golgi pH regulator B chr1 GO:0015267 Not Cancer Driver No 11 0.024 1 0 0.0 0
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0015267 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRIA2_ENST00000264426 GRIA2 P42262 Glutamate receptor 2 chr4 GO:0015267 Not Cancer Driver No 290 0.328 50 16 0.32 14
GRIA3 GRIA3 P42263 Glutamate receptor 3 chrX GO:0015267 Not Cancer Driver No 209 0.234 56 15 0.268 4
GRIA4_ENST00000530497 GRIA4 P48058 Glutamate receptor 4 chr11 GO:0015267 Not Cancer Driver No 227 0.252 63 25 0.397 4
GRID1 GRID1 Q9ULK0 Glutamate receptor ionotropic, delta-1 chr10 GO:0015267 Not Cancer Driver No 276 0.274 204 52 0.255 0
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0015267 Not Cancer Driver No 350 0.348 155 35 0.226 3
GRIK1_ENST00000399907 GRIK1 P39086 Glutamate receptor ionotropic, kainate 1 chr21 GO:0015267 Not Cancer Driver No 196 0.214 50 5 0.1 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0015267 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIK3 GRIK3 Q13003 Glutamate receptor ionotropic, kainate 3 chr1 GO:0015267 Not Cancer Driver No 256 0.279 38 9 0.237 0
GRIK4_ENST00000438375 GRIK4 Q16099 Glutamate receptor ionotropic, kainate 4 chr11 GO:0015267 Not Cancer Driver No 179 0.187 74 8 0.108 0
GRIK5_ENST00000593562 GRIK5 Q16478 Glutamate receptor ionotropic, kainate 5 chr19 GO:0015267 Not Cancer Driver No 176 0.18 135 9 0.067 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0015267 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0015267 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 GO:0015267 Not Cancer Driver No 413 0.278 426 147 0.345 11
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 GO:0015267 Not Cancer Driver No 111 0.09 276 6 0.022 0
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 GO:0015267 Not Cancer Driver No 125 0.094 467 15 0.032 1
GRIN3A GRIN3A Q8TCU5 Glutamate receptor ionotropic, NMDA 3A chr9 GO:0015267 Not Cancer Driver No 308 0.276 179 22 0.123 0
GRIN3B GRIN3B O60391 Glutamate receptor ionotropic, NMDA 3B chr19 GO:0015267 Not Cancer Driver No 90 0.086 299 23 0.077 0
HCN1 HCN1 O60741 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 chr5 GO:0015267 Not Cancer Driver No 432 0.485 365 187 0.512 16
HCN2 HCN2 Q9UL51 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 chr19 GO:0015267 Not Cancer Driver No 75 0.084 342 5 0.015 0
HCN3 HCN3 Q9P1Z3 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 chr1 GO:0015267 Not Cancer Driver No 107 0.138 260 22 0.085 0
HCN4 HCN4 Q9Y3Q4 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 chr15 GO:0015267 Not Cancer Driver No 187 0.155 631 58 0.092 3
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0015267 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTR3A_ENST00000504030 HTR3A P46098 5-hydroxytryptamine receptor 3A chr11 GO:0015267 Not Cancer Driver No 127 0.266 45 13 0.289 0
HTR3B HTR3B O95264 5-hydroxytryptamine receptor 3B chr11 GO:0015267 Not Cancer Driver No 91 0.206 8 0 0.0 0
HTR3C HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C chr3 GO:0015267 Not Cancer Driver No 82 0.183 35 7 0.2 0
HTR3D HTR3D Q70Z44 5-hydroxytryptamine receptor 3D chr3 GO:0015267 Not Cancer Driver No 61 0.134 59 16 0.271 0
HTR3E_ENST00000415389 HTR3E A5X5Y0 5-hydroxytryptamine receptor 3E chr3 GO:0015267 Not Cancer Driver No 87 0.191 56 18 0.321 0
HVCN1_ENST00000620084 HVCN1 Q96D96 Voltage-gated hydrogen channel 1 chr12 GO:0015267 Not Cancer Driver No 51 0.187 52 13 0.25 0
ITPR1_ENST00000354582 ITPR1 Q14643 Inositol 1,4,5-trisphosphate receptor type 1 chr3 GO:0015267 Not Cancer Driver No 390 0.141 581 76 0.131 6
ITPR2 ITPR2 Q14571 Inositol 1,4,5-trisphosphate receptor type 2 chr12 GO:0015267 Not Cancer Driver No 359 0.133 394 57 0.145 1
ITPR3 ITPR3 Q14573 Inositol 1,4,5-trisphosphate receptor type 3 chr6 GO:0015267 Not Cancer Driver No 336 0.126 385 44 0.114 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0015267 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNA10 KCNA10 Q16322 Potassium voltage-gated channel subfamily A member 10 chr1 GO:0015267 Not Cancer Driver No 118 0.231 110 30 0.273 0
KCNA2_ENST00000638616 KCNA2 P16389 Potassium voltage-gated channel subfamily A member 2 chr1 GO:0015267 Not Cancer Driver No 96 0.192 82 16 0.195 5
KCNA3 KCNA3 P22001 Potassium voltage-gated channel subfamily A member 3 chr1 GO:0015267 Not Cancer Driver No 120 0.209 169 16 0.095 0
KCNA5 KCNA5 P22460 Potassium voltage-gated channel subfamily A member 5 chr12 GO:0015267 Not Cancer Driver No 213 0.347 218 53 0.243 0
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0015267 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0015267 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0015267 Not Cancer Driver No 161 0.252 255 63 0.247 0
KCND1 KCND1 Q9NSA2 Potassium voltage-gated channel subfamily D member 1 chrX GO:0015267 Not Cancer Driver No 97 0.15 180 30 0.167 0
KCND2 KCND2 Q9NZV8 Potassium voltage-gated channel subfamily D member 2 chr7 GO:0015267 Not Cancer Driver No 220 0.349 195 62 0.318 0
KCND3 KCND3 Q9UK17 Potassium voltage-gated channel subfamily D member 3 chr1 GO:0015267 Not Cancer Driver No 172 0.263 202 44 0.218 5
KCNE1_ENST00000399284 KCNE1 P15382 Potassium voltage-gated channel subfamily E member 1 chr21 GO:0015267 Not Cancer Driver No 35 0.271 24 10 0.417 9
KCNE2 KCNE2 Q9Y6J6 Potassium voltage-gated channel subfamily E member 2 chr21 GO:0015267 Not Cancer Driver No 25 0.203 2 0 0.0 5
KCNE3 KCNE3 Q9Y6H6 Potassium voltage-gated channel subfamily E member 3 chr11 GO:0015267 Not Cancer Driver No 28 0.272 24 2 0.083 0
KCNE4 KCNE4 Q8WWG9 Potassium voltage-gated channel subfamily E member 4 chr2 GO:0015267 Not Cancer Driver No 26 0.118 94 18 0.191 0
KCNE5 KCNE5 Q9UJ90 Potassium voltage-gated channel subfamily E regulatory beta subunit 5 chrX GO:0015267 Not Cancer Driver No 35 0.246 68 26 0.382 0
KCNH2 KCNH2 Q12809 Potassium voltage-gated channel subfamily H member 2 chr7 GO:0015267 Not Cancer Driver No 189 0.163 466 50 0.107 117
KCNH6 KCNH6 Q9H252 Potassium voltage-gated channel subfamily H member 6 chr17 GO:0015267 Not Cancer Driver No 202 0.203 284 67 0.236 0
KCNH7 KCNH7 Q9NS40 Potassium voltage-gated channel subfamily H member 7 chr2 GO:0015267 Not Cancer Driver No 324 0.271 508 138 0.272 0
KCNIP2_ENST00000356640 KCNIP2 Q9NS61 Kv channel-interacting protein 2 chr10 GO:0015267 Not Cancer Driver No 34 0.126 89 16 0.18 0
KCNJ1 KCNJ1 P48048 ATP-sensitive inward rectifier potassium channel 1 chr11 GO:0015267 Not Cancer Driver No 83 0.212 10 0 0.0 13
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0015267 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0015267 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNJ12_ENST00000331718 KCNJ12 Q14500 ATP-sensitive inward rectifier potassium channel 12 chr17 GO:0015267 Not Cancer Driver No 248 0.573 50 27 0.54 0
KCNJ13_ENST00000410029 KCNJ13 O60928 Inward rectifier potassium channel 13 chr2 GO:0015267 Not Cancer Driver No 39 0.108 44 3 0.068 3
KCNJ14_ENST00000342291 KCNJ14 Q9UNX9 ATP-sensitive inward rectifier potassium channel 14 chr19 GO:0015267 Not Cancer Driver No 56 0.128 73 10 0.137 0
KCNJ15_ENST00000398934 KCNJ15 Q99712 ATP-sensitive inward rectifier potassium channel 15 chr21 GO:0015267 Not Cancer Driver No 85 0.227 12 2 0.167 0
KCNJ16_ENST00000283936 KCNJ16 Q9NPI9 Inward rectifier potassium channel 16 chr17 GO:0015267 Not Cancer Driver No 88 0.211 38 8 0.211 5
KCNJ2_ENST00000535240 KCNJ2 P63252 Inward rectifier potassium channel 2 chr17 GO:0015267 Not Cancer Driver No 103 0.241 49 11 0.224 12
KCNJ3 KCNJ3 P48549 G protein-activated inward rectifier potassium channel 1 chr2 GO:0015267 Not Cancer Driver No 189 0.377 162 64 0.395 0
KCNJ4 KCNJ4 P48050 Inward rectifier potassium channel 4 chr22 GO:0015267 Not Cancer Driver No 103 0.231 62 16 0.258 0
KCNJ5_ENST00000533599 KCNJ5 P48544 G protein-activated inward rectifier potassium channel 4 chr11 GO:0015267 Census Yes 87 0.208 51 6 0.118 6
KCNJ6_ENST00000645093 KCNJ6 P48051 G protein-activated inward rectifier potassium channel 2 chr21 GO:0015267 Not Cancer Driver No 106 0.251 75 13 0.173 1
KCNJ8 KCNJ8 Q15842 ATP-sensitive inward rectifier potassium channel 8 chr12 GO:0015267 Not Cancer Driver No 99 0.233 68 22 0.324 1
KCNJ9 KCNJ9 Q92806 G protein-activated inward rectifier potassium channel 3 chr1 GO:0015267 Not Cancer Driver No 47 0.12 67 1 0.015 0
KCNK1 KCNK1 O00180 Potassium channel subfamily K member 1 chr1 GO:0015267 Not Cancer Driver No 65 0.193 21 4 0.19 0
KCNK10_ENST00000340700 KCNK10 P57789 Potassium channel subfamily K member 10 chr14 GO:0015267 Not Cancer Driver No 138 0.257 174 47 0.27 0
KCNK12 KCNK12 Q9HB15 Potassium channel subfamily K member 12 chr2 GO:0015267 Not Cancer Driver No 6 0.014 29 0 0.0 0
KCNK13 KCNK13 Q9HB14 Potassium channel subfamily K member 13 chr14 GO:0015267 Not Cancer Driver No 99 0.243 32 8 0.25 0
KCNK15 KCNK15 Q9H427 Potassium channel subfamily K member 15 chr20 GO:0015267 Not Cancer Driver No 54 0.164 32 8 0.25 0
KCNK16_ENST00000373229 KCNK16 Q96T55 Potassium channel subfamily K member 16 chr6 GO:0015267 Not Cancer Driver No 63 0.204 14 1 0.071 0
KCNK17 KCNK17 Q96T54 Potassium channel subfamily K member 17 chr6 GO:0015267 Not Cancer Driver No 46 0.139 31 11 0.355 0
KCNK18 KCNK18 Q7Z418 Potassium channel subfamily K member 18 chr10 GO:0015267 Not Cancer Driver No 103 0.268 7 0 0.0 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0015267 Not Cancer Driver No 109 0.256 40 10 0.25 0
KCNK3 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 GO:0015267 Not Cancer Driver No 54 0.137 60 7 0.117 6
KCNK4 KCNK4 Q9NYG8 Potassium channel subfamily K member 4 chr11 GO:0015267 Not Cancer Driver No 34 0.087 142 7 0.049 2
KCNK5 KCNK5 O95279 Potassium channel subfamily K member 5 chr6 GO:0015267 Not Cancer Driver No 94 0.188 206 36 0.175 0
KCNK6 KCNK6 Q9Y257 Potassium channel subfamily K member 6 chr19 GO:0015267 Not Cancer Driver No 39 0.125 22 4 0.182 0
KCNK7 KCNK7 Q9Y2U2 Potassium channel subfamily K member 7 chr11 GO:0015267 Not Cancer Driver No 31 0.101 6 1 0.167 0
KCNK9 KCNK9 Q9NPC2 Potassium channel subfamily K member 9 chr8 GO:0015267 Not Cancer Driver No 139 0.372 58 22 0.379 2
KCNMA1 KCNMA1 Q12791 Calcium-activated potassium channel subunit alpha-1 chr10 GO:0015267 Not Cancer Driver No 222 0.18 225 39 0.173 5
KCNN1 KCNN1 Q92952 Small conductance calcium-activated potassium channel protein 1 chr19 GO:0015267 Not Cancer Driver No 83 0.153 192 19 0.099 0
KCNN2 KCNN2 Q9H2S1 Small conductance calcium-activated potassium channel protein 2 chr5 GO:0015267 Not Cancer Driver No 112 0.193 175 33 0.189 0
KCNN3_ENST00000271915 KCNN3 Q9UGI6 Small conductance calcium-activated potassium channel protein 3 chr1 GO:0015267 Not Cancer Driver No 135 0.185 302 56 0.185 3
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0015267 Not Cancer Driver No 60 0.141 31 6 0.194 3
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0015267 Not Cancer Driver No 78 0.115 219 20 0.091 132
KCNT1_ENST00000488444 KCNT1 Q5JUK3 Potassium channel subfamily T member 1 chr9 GO:0015267 Not Cancer Driver No 187 0.152 328 31 0.095 12
KCNT2 KCNT2 Q6UVM3 Potassium channel subfamily T member 2 chr1 GO:0015267 Not Cancer Driver No 353 0.311 245 89 0.363 1
KCNU1 KCNU1 A8MYU2 Potassium channel subfamily U member 1 chr8 GO:0015267 Not Cancer Driver No 279 0.243 140 40 0.286 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0015267 Not Cancer Driver No 105 0.13 32 3 0.094 0
LRRC8B LRRC8B Q6P9F7 Volume-regulated anion channel subunit LRRC8B chr1 GO:0015267 Not Cancer Driver No 82 0.102 0 0 0.0 0
LRRC8C LRRC8C Q8TDW0 Volume-regulated anion channel subunit LRRC8C chr1 GO:0015267 Not Cancer Driver No 93 0.116 59 6 0.102 0
LRRC8D LRRC8D Q7L1W4 Volume-regulated anion channel subunit LRRC8D chr1 GO:0015267 Not Cancer Driver No 99 0.115 98 18 0.184 0
LRRC8E LRRC8E Q6NSJ5 Volume-regulated anion channel subunit LRRC8E chr19 GO:0015267 Not Cancer Driver No 77 0.097 35 0 0.0 0
MCOLN1 MCOLN1 Q9GZU1 Mucolipin-1 chr19 GO:0015267 Not Cancer Driver No 77 0.133 63 15 0.238 7
MCOLN2 MCOLN2 Q8IZK6 Mucolipin-2 chr1 GO:0015267 Not Cancer Driver No 93 0.164 0 0 0.0 0
MCOLN3 MCOLN3 Q8TDD5 Mucolipin-3 chr1 GO:0015267 Not Cancer Driver No 102 0.184 9 2 0.222 0
MIP MIP P30301 Lens fiber major intrinsic protein chr12 GO:0015267 Not Cancer Driver No 71 0.27 20 1 0.05 6
MPV17 MPV17 P39210 Protein Mpv17 chr2 GO:0015267 Not Cancer Driver No 21 0.119 0 0 0.0 16
NALCN NALCN Q8IZF0 Sodium leak channel NALCN chr13 GO:0015267 Not Cancer Driver No 499 0.287 260 74 0.285 11
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0015267 Not Cancer Driver No 139 0.335 5 1 0.2 0
NOX5 NOX5 Q96PH1 NADPH oxidase 5 chr15 GO:0015267 Not Cancer Driver No 118 0.154 95 9 0.095 0
ORAI1 ORAI1 Q96D31 Calcium release-activated calcium channel protein 1 chr12 GO:0015267 Not Cancer Driver No 26 0.086 101 9 0.089 5
ORAI2 ORAI2 Q96SN7 Protein orai-2 chr7 GO:0015267 Not Cancer Driver No 34 0.134 23 3 0.13 0
ORAI3 ORAI3 Q9BRQ5 Protein orai-3 chr16 GO:0015267 Not Cancer Driver No 31 0.105 93 12 0.129 0
OTOP1 OTOP1 Q7RTM1 Proton channel OTOP1 chr4 GO:0015267 Not Cancer Driver No 104 0.17 89 11 0.124 0
OTOP2 OTOP2 Q7RTS6 Proton channel OTOP2 chr17 GO:0015267 Not Cancer Driver No 79 0.141 48 11 0.229 0
OTOP3 OTOP3 Q7RTS5 Proton channel OTOP3 chr17 GO:0015267 Not Cancer Driver No 95 0.159 68 6 0.088 0
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0015267 Not Cancer Driver No 59 0.148 14 1 0.071 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0015267 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0015267 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0015267 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0015267 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RX6 P2RX6 O15547 P2X purinoceptor 6 chr22 GO:0015267 Not Cancer Driver No 33 0.075 43 1 0.023 0
P2RX7 P2RX7 Q99572 P2X purinoceptor 7 chr12 GO:0015267 Not Cancer Driver No 51 0.086 14 2 0.143 0
PANX1 PANX1 Q96RD7 Pannexin-1 chr11 GO:0015267 Not Cancer Driver No 54 0.127 45 7 0.156 2
PANX2 PANX2 Q96RD6 Pannexin-2 chr22 GO:0015267 Not Cancer Driver No 73 0.108 293 14 0.048 0
PANX3 PANX3 Q96QZ0 Pannexin-3 chr11 GO:0015267 Not Cancer Driver No 92 0.235 10 4 0.4 0
PDPN_ENST00000621990 PDPN Q86YL7 Podoplanin chr1 GO:0015267 Not Cancer Driver No 37 0.228 96 24 0.25 0
PEX5L PEX5L Q8IYB4 PEX5-related protein chr3 GO:0015267 Not Cancer Driver No 152 0.243 346 103 0.298 0
PIEZO1 PIEZO1 Q92508 Piezo-type mechanosensitive ion channel component 1 chr16 GO:0015267 Not Cancer Driver No 122 0.048 471 26 0.055 12
PIEZO2 PIEZO2 Q9H5I5 Piezo-type mechanosensitive ion channel component 2 chr18 GO:0015267 Not Cancer Driver No 198 0.072 603 19 0.032 8
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0015267 Not Cancer Driver No 113 0.117 375 35 0.093 10
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0015267 Not Cancer Driver No 161 0.16 261 37 0.142 0
RASA3 RASA3 Q14644 Ras GTPase-activating protein 3 chr13 GO:0015267 Not Cancer Driver No 118 0.141 101 19 0.188 0
RHAG RHAG Q02094 Ammonium transporter Rh type A chr6 GO:0015267 Not Cancer Driver No 102 0.249 0 0 0.0 6
RHBG RHBG Q9H310 Ammonium transporter Rh type B chr1 GO:0015267 Not Cancer Driver No 66 0.144 32 7 0.219 0
RHCE RHCE P18577 Blood group Rh(CE) polypeptide chr1 GO:0015267 Not Cancer Driver No 64 0.153 8 5 0.625 0
RHCG RHCG Q9UBD6 Ammonium transporter Rh type C chr15 GO:0015267 Not Cancer Driver No 74 0.154 19 2 0.105 0
RHD_ENST00000328664 RHD Q02161 Blood group Rh(D) polypeptide chr1 GO:0015267 Not Cancer Driver No 55 0.132 9 0 0.0 0
RYR1 RYR1 P21817 Ryanodine receptor 1 chr19 GO:0015267 Not Cancer Driver No 1003 0.199 1186 233 0.196 154
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0015267 Not Cancer Driver No 1703 0.343 782 281 0.359 51
RYR3 RYR3 Q15413 Ryanodine receptor 3 chr15 GO:0015267 Not Cancer Driver No 1079 0.222 649 162 0.25 0
SCN10A SCN10A Q9Y5Y9 Sodium channel protein type 10 subunit alpha chr3 GO:0015267 Not Cancer Driver No 513 0.262 435 131 0.301 2
SCN11A SCN11A Q9UI33 Sodium channel protein type 11 subunit alpha chr3 GO:0015267 Not Cancer Driver No 475 0.265 198 61 0.308 9
SCN1A_ENST00000423058 SCN1A P35498 Sodium channel protein type 1 subunit alpha chr2 GO:0015267 Not Cancer Driver No 497 0.247 455 121 0.266 396
SCN1B_ENST00000262631 SCN1B Q07699 Sodium channel subunit beta-1 chr19 GO:0015267 Not Cancer Driver No 35 0.161 4 1 0.25 5
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0015267 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCN2B SCN2B O60939 Sodium channel subunit beta-2 chr11 GO:0015267 Not Cancer Driver No 46 0.214 52 7 0.135 2
SCN3A_ENST00000360093 SCN3A Q9NY46 Sodium channel protein type 3 subunit alpha chr2 GO:0015267 Not Cancer Driver No 415 0.207 432 83 0.192 6
SCN3B_ENST00000299333 SCN3B Q9NY72 Sodium channel subunit beta-3 chr11 GO:0015267 Not Cancer Driver No 63 0.293 16 5 0.312 3
SCN4A SCN4A P35499 Sodium channel protein type 4 subunit alpha chr17 GO:0015267 Not Cancer Driver No 324 0.176 372 80 0.215 60
SCN4B SCN4B Q8IWT1 Sodium channel subunit beta-4 chr11 GO:0015267 Not Cancer Driver No 23 0.101 46 4 0.087 3
SCN5A_ENST00000333535 SCN5A Q14524 Sodium channel protein type 5 subunit alpha chr3 GO:0015267 Not Cancer Driver No 491 0.244 550 144 0.262 190
SCN7A_ENST00000409855 SCN7A Q01118 Sodium channel protein type 7 subunit alpha chr2 GO:0015267 Not Cancer Driver No 395 0.235 171 43 0.251 0
SCN8A SCN8A Q9UQD0 Sodium channel protein type 8 subunit alpha chr12 GO:0015267 Not Cancer Driver No 290 0.146 460 75 0.163 28
SCN9A_ENST00000642356 SCN9A Q15858 Sodium channel protein type 9 subunit alpha chr2 GO:0015267 Not Cancer Driver No 461 0.232 490 126 0.257 21
SCNN1A_ENST00000228916 SCNN1A P37088 Amiloride-sensitive sodium channel subunit alpha chr12 GO:0015267 Not Cancer Driver No 73 0.109 146 21 0.144 5
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0015267 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCNN1D SCNN1D P51172 Amiloride-sensitive sodium channel subunit delta chr1 GO:0015267 Not Cancer Driver No 56 0.07 210 9 0.043 0
SCNN1G SCNN1G P51170 Amiloride-sensitive sodium channel subunit gamma chr16 GO:0015267 Not Cancer Driver No 129 0.199 57 11 0.193 0
SHROOM2 SHROOM2 Q13796 Protein Shroom2 chrX GO:0015267 Not Cancer Driver No 215 0.133 1381 188 0.136 0
SLC12A2 SLC12A2 P55011 Solute carrier family 12 member 2 chr5 GO:0015267 Not Cancer Driver No 141 0.116 297 18 0.061 8
SLC12A4_ENST00000316341 SLC12A4 Q9UP95 Solute carrier family 12 member 4 chr16 GO:0015267 Not Cancer Driver No 122 0.112 171 17 0.099 0
SLC12A5 SLC12A5 Q9H2X9 Solute carrier family 12 member 5 chr20 GO:0015267 Not Cancer Driver No 263 0.231 290 59 0.203 5
SLC12A6_ENST00000558667 SLC12A6 Q9UHW9 Solute carrier family 12 member 6 chr15 GO:0015267 Not Cancer Driver No 168 0.146 280 46 0.164 0
SLC12A7 SLC12A7 Q9Y666 Solute carrier family 12 member 7 chr5 GO:0015267 Not Cancer Driver No 153 0.141 202 23 0.114 0
SLC14A1_ENST00000586951 SLC14A1 Q13336 Urea transporter 1 chr18 GO:0015267 Not Cancer Driver No 90 0.231 22 5 0.227 0
SLC17A3_ENST00000360657 SLC17A3 O00476 Sodium-dependent phosphate transport protein 4 chr6 GO:0015267 Not Cancer Driver No 97 0.231 26 6 0.231 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0015267 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC4A11_ENST00000539553 SLC4A11 Q8NBS3 Solute carrier family 4 member 11 chr20 GO:0015267 Not Cancer Driver No 159 0.182 69 10 0.145 42
STEAP1 STEAP1 Q9UHE8 Metalloreductase STEAP1 chr7 GO:0015267 Not Cancer Driver No 45 0.133 26 3 0.115 0
STIM2_ENST00000467087 STIM2 Q9P246 Stromal interaction molecule 2 chr4 GO:0015267 Not Cancer Driver No 82 0.11 387 45 0.116 0
TMC1 TMC1 Q8TDI8 Transmembrane channel-like protein 1 chr9 GO:0015267 Not Cancer Driver No 121 0.159 97 10 0.103 2
TMC2 TMC2 Q8TDI7 Transmembrane channel-like protein 2 chr20 GO:0015267 Not Cancer Driver No 180 0.199 293 44 0.15 0
TMC3 TMC3 Q7Z5M5 Transmembrane channel-like protein 3 chr15 GO:0015267 Not Cancer Driver No 176 0.16 389 67 0.172 0
TMC4 TMC4 Q7Z404 Transmembrane channel-like protein 4 chr19 GO:0015267 Not Cancer Driver No 100 0.14 143 37 0.259 0
TMC5 TMC5 Q6UXY8 Transmembrane channel-like protein 5 chr16 GO:0015267 Not Cancer Driver No 198 0.197 387 93 0.24 0
TMC6 TMC6 Q7Z403 Transmembrane channel-like protein 6 chr17 GO:0015267 Not Cancer Driver No 72 0.089 129 9 0.07 0
TMC7_ENST00000304381 TMC7 Q7Z402 Transmembrane channel-like protein 7 chr16 GO:0015267 Not Cancer Driver No 116 0.16 71 9 0.127 0
TMC8 TMC8 Q8IU68 Transmembrane channel-like protein 8 chr17 GO:0015267 Not Cancer Driver No 61 0.084 107 10 0.093 0
TMEM150C TMEM150C B9EJG8 Transmembrane protein 150C chr4 GO:0015267 Not Cancer Driver No 38 0.153 0 0 0.0 0
TMEM175 TMEM175 Q9BSA9 Endosomal/lysosomal potassium channel TMEM175 chr4 GO:0015267 Not Cancer Driver No 77 0.153 51 13 0.255 0
TMEM206_ENST00000261455 PACC1 Q9H813 Proton-activated chloride channel chr1 GO:0015267 Not Cancer Driver No 51 0.146 32 5 0.156 0
TMEM266 TMEM266 Q2M3C6 Transmembrane protein 266 chr15 GO:0015267 Not Cancer Driver No 77 0.145 239 28 0.117 0
TMEM63A TMEM63A O94886 CSC1-like protein 1 chr1 GO:0015267 Not Cancer Driver No 87 0.108 36 1 0.028 3
TMEM63B TMEM63B Q5T3F8 CSC1-like protein 2 chr6 GO:0015267 Not Cancer Driver No 108 0.13 78 12 0.154 0
TMEM63C TMEM63C Q9P1W3 Calcium permeable stress-gated cation channel 1 chr14 GO:0015267 Not Cancer Driver No 114 0.141 84 14 0.167 0
TOMM40L_ENST00000367987 TOMM40L Q969M1 Mitochondrial import receptor subunit TOM40B chr1 GO:0015267 Not Cancer Driver No 29 0.094 32 4 0.125 0
TOMM40_ENST00000405636 TOMM40 O96008 Mitochondrial import receptor subunit TOM40 homolog chr19 GO:0015267 Not Cancer Driver No 17 0.047 98 1 0.01 0
TPCN1_ENST00000335509 TPCN1 Q9ULQ1 Two pore channel protein 1 chr12 GO:0015267 Not Cancer Driver No 114 0.14 99 18 0.182 0
TPCN2 TPCN2 Q8NHX9 Two pore channel protein 2 chr11 GO:0015267 Not Cancer Driver No 73 0.097 16 0 0.0 0
TRPA1 TRPA1 O75762 Transient receptor potential cation channel subfamily A member 1 chr8 GO:0015267 Not Cancer Driver No 324 0.29 62 14 0.226 1
TRPC1 TRPC1 P48995 Short transient receptor potential channel 1 chr3 GO:0015267 Not Cancer Driver No 143 0.18 52 11 0.212 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0015267 Not Cancer Driver No 200 0.239 23 2 0.087 1
TRPC4_ENST00000379705 TRPC4 Q9UBN4 Short transient receptor potential channel 4 chr13 GO:0015267 Not Cancer Driver No 322 0.33 195 66 0.338 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0015267 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPC6 TRPC6 Q9Y210 Short transient receptor potential channel 6 chr11 GO:0015267 Not Cancer Driver No 202 0.217 165 46 0.279 10
TRPC7 TRPC7 Q9HCX4 Short transient receptor potential channel 7 chr5 GO:0015267 Not Cancer Driver No 224 0.26 106 39 0.368 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0015267 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0015267 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPM5 TRPM5 Q9NZQ8 Transient receptor potential cation channel subfamily M member 5 chr11 GO:0015267 Not Cancer Driver No 123 0.106 186 19 0.102 0
TRPM8 TRPM8 Q7Z2W7 Transient receptor potential cation channel subfamily M member 8 chr2 GO:0015267 Not Cancer Driver No 206 0.187 43 11 0.256 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0015267 Not Cancer Driver No 93 0.111 155 18 0.116 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0015267 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSPOAP1 TSPOAP1 O95153 Peripheral-type benzodiazepine receptor-associated protein 1 chr17 GO:0015267 Not Cancer Driver No 268 0.144 1522 213 0.14 0
TTYH1_ENST00000376530 TTYH1 Q9H313 Protein tweety homolog 1 chr19 GO:0015267 Not Cancer Driver No 56 0.124 21 3 0.143 0
TTYH2 TTYH2 Q9BSA4 Protein tweety homolog 2 chr17 GO:0015267 Not Cancer Driver No 63 0.118 68 19 0.279 0
TTYH3 TTYH3 Q9C0H2 Protein tweety homolog 3 chr7 GO:0015267 Not Cancer Driver No 48 0.092 91 14 0.154 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0015267 Not Cancer Driver No 38 0.134 36 4 0.111 0
VDAC2_ENST00000543351 VDAC2 P45880 Voltage-dependent anion-selective channel protein 2 chr10 GO:0015267 Not Cancer Driver No 35 0.119 9 1 0.111 0
VDAC3_ENST00000022615 VDAC3 Q9Y277 Voltage-dependent anion-selective channel protein 3 chr8 GO:0015267 Not Cancer Driver No 24 0.085 0 0 0.0 0
ZACN ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 GO:0015267 Not Cancer Driver No 46 0.112 48 6 0.125 0