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Total number of protein in "GO:0014066" GO term:  104

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AGT AGT P01019 Angiotensinogen chr1 GO:0014066 Not Cancer Driver No 85 0.179 33 10 0.303 1
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0014066 Not Cancer Driver No 130 0.261 131 24 0.183 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0014066 Not Cancer Driver No 45 0.1 190 19 0.1 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0014066 Not Cancer Driver No 92 0.176 24 2 0.083 0
CAT CAT P04040 Catalase chr11 GO:0014066 Not Cancer Driver No 70 0.133 176 18 0.102 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0014066 Census, Compendium Yes 115 0.127 512 56 0.109 4
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0014066 Census Yes 42 0.191 18 10 0.556 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0014066 Not Cancer Driver No 64 0.122 241 25 0.104 0
CEP55 CEP55 Q53EZ4 Centrosomal protein of 55 kDa chr10 GO:0014066 Not Cancer Driver No 59 0.127 264 26 0.098 0
CRNN CRNN Q9UBG3 Cornulin chr1 GO:0014066 Not Cancer Driver No 109 0.22 421 95 0.226 1
CRYBA1 CRYBA1 P05813 Beta-crystallin A3 chr17 GO:0014066 Not Cancer Driver No 29 0.135 52 11 0.212 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0014066 Not Cancer Driver No 20 0.097 7 0 0.0 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0014066 Not Cancer Driver No 131 0.11 681 68 0.1 0
DCN DCN P07585 Decorin chr12 GO:0014066 Not Cancer Driver No 96 0.267 81 26 0.321 0
DIPK2A DIPK2A Q8NDZ4 Divergent protein kinase domain 2A chr3 GO:0014066 Not Cancer Driver No 56 0.13 9 0 0.0 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0014066 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0014066 Census, Compendium Yes 444 0.367 223 35 0.157 1
ENTPD5 ENTPD5 O75356 Nucleoside diphosphate phosphatase ENTPD5 chr14 GO:0014066 Not Cancer Driver No 41 0.096 6 1 0.167 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0014066 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0014066 Census, Compendium Yes 428 0.327 323 116 0.359 2
F2 F2 P00734 Prothrombin chr11 GO:0014066 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0014066 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0014066 Not Cancer Driver No 55 0.139 7 2 0.286 0
FBXL2 FBXL2 Q9UKC9 F-box/LRR-repeat protein 2 chr3 GO:0014066 Not Cancer Driver No 48 0.113 0 0 0.0 0
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0014066 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0014066 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0014066 Not Cancer Driver No 85 0.161 52 8 0.154 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0014066 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0014066 Census, Compendium Yes 200 0.201 64 27 0.422 0
FN1 FN1 P02751 Fibronectin chr2 GO:0014066 Compendium Yes 394 0.159 1243 185 0.149 8
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0014066 Not Cancer Driver No 226 0.325 28 11 0.393 16
GH1 GH1 P01241 Somatotropin chr17 GO:0014066 Not Cancer Driver No 54 0.249 24 9 0.375 15
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0014066 Not Cancer Driver No 65 0.173 13 5 0.385 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0014066 Not Cancer Driver No 44 0.158 219 32 0.146 2
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0014066 Not Cancer Driver No 103 0.212 446 94 0.211 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 GO:0014066 Not Cancer Driver No 6 0.065 12 0 0.0 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0014066 Compendium Yes 233 0.32 43 16 0.372 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0014066 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0014066 Not Cancer Driver No 45 0.231 87 23 0.264 0
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0014066 Not Cancer Driver No 19 0.098 16 3 0.188 0
INPP5E INPP5E Q9NRR6 Phosphatidylinositol polyphosphate 5-phosphatase type IV chr9 GO:0014066 Not Cancer Driver No 43 0.067 272 16 0.059 15
INS INS P01308 Insulin chr11 GO:0014066 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0014066 Not Cancer Driver No 190 0.137 280 57 0.204 64
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0014066 Census, Compendium Yes 136 0.12 59 5 0.085 5
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0014066 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0014066 Census, Compendium Yes 226 0.232 83 33 0.398 21
LEP LEP P41159 Leptin chr7 GO:0014066 Not Cancer Driver No 29 0.174 0 0 0.0 2
LIME1 LIME1 Q9H400 Lck-interacting transmembrane adapter 1 chr20 GO:0014066 Not Cancer Driver No 22 0.075 193 17 0.088 0
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0014066 Not Cancer Driver No 46 0.096 249 22 0.088 0
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0014066 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYOC MYOC Q99972 Myocilin chr1 GO:0014066 Not Cancer Driver No 92 0.183 196 43 0.219 58
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0014066 Not Cancer Driver No 37 0.095 181 12 0.066 1
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0014066 Not Cancer Driver No 150 0.114 711 79 0.111 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0014066 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLRC3 NLRC3 Q7RTR2 NLR family CARD domain-containing protein 3 chr16 GO:0014066 Not Cancer Driver No 176 0.165 147 33 0.224 0
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0014066 Not Cancer Driver No 59 0.123 391 41 0.105 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0014066 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0014066 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0014066 Census, Compendium Yes 249 0.297 57 21 0.368 0
OSM OSM P13725 Oncostatin-M chr22 GO:0014066 Not Cancer Driver No 43 0.171 114 24 0.211 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0014066 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0014066 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0014066 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0014066 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0014066 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0014066 Census, Compendium Yes 164 0.148 231 44 0.19 7
PIK3AP1 PIK3AP1 Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 chr10 GO:0014066 Not Cancer Driver No 141 0.175 406 81 0.2 0
PIK3IP1 PIK3IP1 Q96FE7 Phosphoinositide-3-kinase-interacting protein 1 chr22 GO:0014066 Not Cancer Driver No 27 0.103 128 13 0.102 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0014066 Not Cancer Driver No 74 0.132 216 29 0.134 0
PIP5K1B PIP5K1B O14986 Phosphatidylinositol 4-phosphate 5-kinase type-1 beta chr9 GO:0014066 Not Cancer Driver No 94 0.174 162 36 0.222 0
PIP5K1C_ENST00000335312 PIP5K1C O60331 Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma chr19 GO:0014066 Not Cancer Driver No 98 0.147 360 60 0.167 1
PLGLB2 PLGLB2 Q02325 Plasminogen-like protein B chr2 GO:0014066 Not Cancer Driver No 2 0.021 0 0 0.0 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:0014066 Not Cancer Driver No 228 0.107 684 67 0.098 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0014066 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPP1R16B PPP1R16B Q96T49 Protein phosphatase 1 regulatory inhibitor subunit 16B chr20 GO:0014066 Not Cancer Driver No 132 0.233 220 66 0.3 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0014066 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 GO:0014066 Not Cancer Driver No 50 0.129 173 22 0.127 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0014066 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0014066 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTPN13_ENST00000411767 PTPN13 Q12923 Tyrosine-protein phosphatase non-receptor type 13 chr4 GO:0014066 Census, Compendium Yes 299 0.12 1231 149 0.121 0
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0014066 Census, Compendium Yes 73 0.123 192 25 0.13 0
RASGRP1 RASGRP1 O95267 RAS guanyl-releasing protein 1 chr15 GO:0014066 Not Cancer Driver No 96 0.12 191 12 0.063 1
RELN RELN P78509 Reelin chr7 GO:0014066 Not Cancer Driver No 761 0.22 107 19 0.178 7
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:0014066 Not Cancer Driver No 87 0.112 461 51 0.111 0
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:0014066 Not Cancer Driver No 144 0.154 280 43 0.154 1
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0014066 Not Cancer Driver No 203 0.215 299 71 0.237 5
SELP SELP P16109 P-selectin chr1 GO:0014066 Not Cancer Driver No 226 0.272 14 2 0.143 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0014066 Not Cancer Driver No 117 0.136 132 15 0.114 0
SERPINA12 SERPINA12 Q8IW75 Serpin A12 chr14 GO:0014066 Not Cancer Driver No 90 0.217 22 3 0.136 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0014066 Not Cancer Driver No 62 0.156 0 0 0.0 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0014066 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0014066 Not Cancer Driver No 19 0.053 318 16 0.05 4
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0014066 Compendium Yes 86 0.169 495 82 0.166 18
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0014066 Census Yes 53 0.099 130 11 0.085 1
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0014066 Not Cancer Driver No 51 0.12 139 16 0.115 6
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0014066 Not Cancer Driver No 219 0.195 126 22 0.175 10
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0014066 Not Cancer Driver No 63 0.152 47 8 0.17 3
TNF TNF P01375 Tumor necrosis factor chr6 GO:0014066 Not Cancer Driver No 24 0.103 45 3 0.067 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0014066 Not Cancer Driver No 43 0.187 27 2 0.074 1
TSC2 TSC2 P49815 Tuberin chr16 GO:0014066 Census, Compendium Yes 192 0.106 563 50 0.089 53
TWIST1 TWIST1 Q15672 Twist-related protein 1 chr7 GO:0014066 Not Cancer Driver No 23 0.114 132 11 0.083 7
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0014066 Not Cancer Driver No 141 0.161 136 22 0.162 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0014066 Not Cancer Driver No 155 0.164 117 20 0.171 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0014066 Not Cancer Driver No 59 0.162 28 9 0.321 0