Total number of protein in "GO:0014065" GO term: 36
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0014065 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | GO:0014065 | Not Cancer Driver | No | 14 | 0.05 | 103 | 6 | 0.058 | 2 |
CD160_ENST00000369288 | CD160 | O95971 | CD160 antigen | chr1 | GO:0014065 | Not Cancer Driver | No | 20 | 0.11 | 2 | 0 | 0.0 | 0 |
EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0014065 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0014065 | Census, Compendium | Yes | 275 | 0.219 | 314 | 41 | 0.131 | 1 |
ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0014065 | Census, Compendium | Yes | 298 | 0.222 | 396 | 70 | 0.177 | 3 |
GATA3_ENST00000346208 | GATA3 | P23771 | Trans-acting T-cell-specific transcription factor GATA-3 | chr10 | GO:0014065 | Census, Compendium | Yes | 111 | 0.251 | 364 | 87 | 0.239 | 2 |
HTR2A | HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | chr13 | GO:0014065 | Not Cancer Driver | No | 105 | 0.223 | 44 | 8 | 0.182 | 0 |
HTR2B | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | GO:0014065 | Not Cancer Driver | No | 41 | 0.085 | 23 | 2 | 0.087 | 0 |
IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0014065 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0014065 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0014065 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
KBTBD2 | KBTBD2 | Q8IY47 | Kelch repeat and BTB domain-containing protein 2 | chr7 | GO:0014065 | Not Cancer Driver | No | 72 | 0.116 | 25 | 4 | 0.16 | 0 |
LTK | LTK | P29376 | Leukocyte tyrosine kinase receptor | chr15 | GO:0014065 | Not Cancer Driver | No | 103 | 0.119 | 301 | 30 | 0.1 | 0 |
MYO16_ENST00000357550 | MYO16 | Q9Y6X6 | Unconventional myosin-XVI | chr13 | GO:0014065 | Not Cancer Driver | No | 412 | 0.222 | 681 | 112 | 0.164 | 0 |
NF1 | NF1 | P21359 | Neurofibromin | chr17 | GO:0014065 | Census, Compendium | Yes | 375 | 0.132 | 406 | 47 | 0.116 | 85 |
NYAP1 | NYAP1 | Q6ZVC0 | Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 | chr7 | GO:0014065 | Not Cancer Driver | No | 128 | 0.152 | 792 | 126 | 0.159 | 0 |
NYAP2 | NYAP2 | Q9P242 | Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 | chr2 | GO:0014065 | Not Cancer Driver | No | 237 | 0.363 | 618 | 223 | 0.361 | 0 |
PEAR1 | PEAR1 | Q5VY43 | Platelet endothelial aggregation receptor 1 | chr1 | GO:0014065 | Not Cancer Driver | No | 152 | 0.147 | 233 | 42 | 0.18 | 0 |
PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0014065 | Not Cancer Driver | No | 187 | 0.111 | 350 | 43 | 0.123 | 0 |
PIK3C2B | PIK3C2B | O00750 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta | chr1 | GO:0014065 | Not Cancer Driver | No | 241 | 0.147 | 425 | 71 | 0.167 | 0 |
PIK3C2G_ENST00000433979 | PIK3C2G | O75747 | Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma | chr12 | GO:0014065 | Not Cancer Driver | No | 283 | 0.196 | 211 | 37 | 0.175 | 0 |
PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0014065 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0014065 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0014065 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0014065 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0014065 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
PIK3R2_ENST00000617130 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0014065 | Not Cancer Driver | No | 96 | 0.132 | 418 | 47 | 0.112 | 3 |
PIK3R5 | PIK3R5 | Q8WYR1 | Phosphoinositide 3-kinase regulatory subunit 5 | chr17 | GO:0014065 | Not Cancer Driver | No | 143 | 0.163 | 316 | 55 | 0.174 | 1 |
PLEKHA1 | PLEKHA1 | Q9HB21 | Pleckstrin homology domain-containing family A member 1 | chr10 | GO:0014065 | Not Cancer Driver | No | 61 | 0.151 | 191 | 32 | 0.168 | 0 |
PREX2 | PREX2 | Q70Z35 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein | chr8 | GO:0014065 | Census, Compendium | Yes | 492 | 0.306 | 234 | 68 | 0.291 | 0 |
PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0014065 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0014065 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
TPTE2 | TPTE2 | Q6XPS3 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 | chr13 | GO:0014065 | Not Cancer Driver | No | 210 | 0.402 | 33 | 13 | 0.394 | 0 |
TYRO3 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0014065 | Not Cancer Driver | No | 119 | 0.134 | 197 | 17 | 0.086 | 0 |
ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0014065 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |