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Total number of protein in "GO:0010975" GO term:  273

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI2_ENST00000261018 ABI2 Q9NYB9 Abl interactor 2 chr2 GO:0010975 Not Cancer Driver No 56 0.109 361 38 0.105 0
ABI3 ABI3 Q9P2A4 ABI gene family member 3 chr17 GO:0010975 Not Cancer Driver No 46 0.126 248 31 0.125 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0010975 Census, Compendium Yes 139 0.123 604 73 0.121 2
AC006486.1 AC006486.1 M0QYV0 Protein kinase domain-containing protein (Fragment) chr19 GO:0010975 Not Cancer Driver No 23 0.138 21 1 0.048 0
ACAP3 ACAP3 Q96P50 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 chr1 GO:0010975 Not Cancer Driver No 68 0.082 216 7 0.032 0
ACP4 ACP4 Q9BZG2 Testicular acid phosphatase chr19 GO:0010975 Not Cancer Driver No 66 0.155 28 7 0.25 3
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0010975 Not Cancer Driver No 51 0.129 6 2 0.333 0
ADCY6 ADCY6 O43306 Adenylate cyclase type 6 chr12 GO:0010975 Not Cancer Driver No 144 0.123 147 17 0.116 1
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0010975 Not Cancer Driver No 130 0.118 615 66 0.107 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0010975 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0010975 Census, Compendium Yes 303 0.187 575 114 0.198 16
AMIGO3 AMIGO3 Q86WK7 Amphoterin-induced protein 3 chr3 GO:0010975 Not Cancer Driver No 69 0.137 60 7 0.117 0
ANAPC2 ANAPC2 Q9UJX6 Anaphase-promoting complex subunit 2 chr9 GO:0010975 Not Cancer Driver No 104 0.127 146 26 0.178 0
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0010975 Not Cancer Driver No 145 0.138 239 33 0.138 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0010975 Not Cancer Driver No 25 0.079 124 6 0.048 12
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 GO:0010975 Not Cancer Driver No 64 0.162 194 29 0.149 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0010975 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARHGAP44 ARHGAP44 Q17R89 Rho GTPase-activating protein 44 chr17 GO:0010975 Not Cancer Driver No 126 0.154 424 67 0.158 0
ARHGAP4_ENST00000350060 ARHGAP4 P98171 Rho GTPase-activating protein 4 chrX GO:0010975 Not Cancer Driver No 125 0.132 464 76 0.164 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0010975 Census, Compendium Yes 34 0.286 5 1 0.2 2
BAG5_ENST00000299204 BAG5 Q9UL15 BAG family molecular chaperone regulator 5 chr14 GO:0010975 Not Cancer Driver No 37 0.083 63 7 0.111 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0010975 Not Cancer Driver No 85 0.154 330 52 0.158 0
BCL11A BCL11A Q9H165 B-cell lymphoma/leukemia 11A chr2 GO:0010975 Census, Compendium Yes 210 0.251 677 171 0.253 3
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0010975 Not Cancer Driver No 47 0.19 79 19 0.241 1
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0010975 Not Cancer Driver No 88 0.161 267 38 0.142 0
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0010975 Census Yes 163 0.359 112 62 0.554 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0010975 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0010975 Compendium Yes 141 0.136 601 70 0.116 19
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0010975 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0010975 Not Cancer Driver No 90 0.122 321 39 0.121 0
CAMK2B CAMK2B Q13554 Calcium/calmodulin-dependent protein kinase type II subunit beta chr7 GO:0010975 Not Cancer Driver No 86 0.129 273 28 0.103 6
CAMK2G_ENST00000423381 CAMK2G Q13555 Calcium/calmodulin-dependent protein kinase type II subunit gamma chr10 GO:0010975 Not Cancer Driver No 68 0.122 145 14 0.097 1
CAPRIN1_ENST00000532820 CAPRIN1 Q14444 Caprin-1 chr11 GO:0010975 Not Cancer Driver No 84 0.118 603 72 0.119 0
CARM1 CARM1 Q86X55 Histone-arginine methyltransferase CARM1 chr19 GO:0010975 Not Cancer Driver No 62 0.102 102 10 0.098 0
CBFA2T2 CBFA2T2 O43439 Protein CBFA2T2 chr20 GO:0010975 Not Cancer Driver No 89 0.147 457 58 0.127 0
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0010975 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0010975 Not Cancer Driver No 54 0.18 3 1 0.333 0
CDH4 CDH4 P55283 Cadherin-4 chr20 GO:0010975 Not Cancer Driver No 266 0.29 441 152 0.345 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0010975 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0010975 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDKL3 CDKL3 Q8IVW4 Cyclin-dependent kinase-like 3 chr5 GO:0010975 Not Cancer Driver No 68 0.115 278 40 0.144 0
CDKL5_ENST00000623535 CDKL5 O76039 Cyclin-dependent kinase-like 5 chrX GO:0010975 Not Cancer Driver No 165 0.172 685 120 0.175 18
CERS2_ENST00000368954 CERS2 Q96G23 Ceramide synthase 2 chr1 GO:0010975 Not Cancer Driver No 38 0.1 36 4 0.111 0
CFL1_ENST00000308162 CFL1 P23528 Cofilin-1 chr11 GO:0010975 Not Cancer Driver No 21 0.127 4 0 0.0 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0010975 Not Cancer Driver No 24 0.126 6 1 0.167 0
CNTF CNTF P26441 Ciliary neurotrophic factor chr11 GO:0010975 Not Cancer Driver No 41 0.205 34 5 0.147 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0010975 Not Cancer Driver No 155 0.149 370 61 0.165 0
COBL_ENST00000265136 COBL O75128 Protein cordon-bleu chr7 GO:0010975 Not Cancer Driver No 233 0.185 1149 216 0.188 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0010975 Not Cancer Driver No 27 0.196 23 6 0.261 0
CRMP1_ENST00000397890 CRMP1 Q14194 Dihydropyrimidinase-related protein 1 chr4 GO:0010975 Not Cancer Driver No 122 0.213 96 15 0.156 0
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:0010975 Census, Compendium Yes 63 0.099 606 62 0.102 0
CTNNA2 CTNNA2 P26232 Catenin alpha-2 chr2 GO:0010975 Census Yes 387 0.406 307 130 0.423 0
CUL7_ENST00000265348 CUL7 Q14999 Cullin-7 chr6 GO:0010975 Not Cancer Driver No 188 0.111 372 41 0.11 3
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0010975 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0010975 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0010975 Not Cancer Driver No 46 0.037 96 0 0.0 0
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0010975 Not Cancer Driver No 200 0.34 393 143 0.364 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0010975 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0010975 Not Cancer Driver No 131 0.11 681 68 0.1 0
DBN1_ENST00000309007 DBN1 Q16643 Drebrin chr5 GO:0010975 Not Cancer Driver No 84 0.129 510 73 0.143 0
DBNL_ENST00000448521 DBNL Q9UJU6 Drebrin-like protein chr7 GO:0010975 Not Cancer Driver No 46 0.107 304 31 0.102 0
DCC DCC P43146 Netrin receptor DCC chr18 GO:0010975 Census, Compendium Yes 530 0.366 631 215 0.341 2
DENND5A DENND5A Q6IQ26 DENN domain-containing protein 5A chr11 GO:0010975 Not Cancer Driver No 134 0.104 231 21 0.091 0
DGUOK DGUOK Q16854 Deoxyguanosine kinase, mitochondrial chr2 GO:0010975 Not Cancer Driver No 25 0.09 17 1 0.059 6
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0010975 Not Cancer Driver No 159 0.158 222 39 0.176 0
DIP2B DIP2B Q9P265 Disco-interacting protein 2 homolog B chr12 GO:0010975 Not Cancer Driver No 181 0.115 375 49 0.131 0
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0010975 Not Cancer Driver No 132 0.155 514 82 0.16 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0010975 Not Cancer Driver No 58 0.218 47 8 0.17 0
DNM3_ENST00000355305 DNM3 Q9UQ16 Dynamin-3 chr1 GO:0010975 Not Cancer Driver No 166 0.191 257 45 0.175 0
DPYSL3_ENST00000398514 DPYSL3 Q14195 Dihydropyrimidinase-related protein 3 chr5 GO:0010975 Not Cancer Driver No 93 0.163 128 14 0.109 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0010975 Not Cancer Driver No 61 0.175 249 48 0.193 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0010975 Not Cancer Driver No 652 0.324 603 201 0.333 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0010975 Not Cancer Driver No 49 0.14 210 25 0.119 0
EEF2K EEF2K O00418 Eukaryotic elongation factor 2 kinase chr16 GO:0010975 Not Cancer Driver No 104 0.143 311 39 0.125 0
EFHC2 EFHC2 Q5JST6 EF-hand domain-containing family member C2 chrX GO:0010975 Not Cancer Driver No 113 0.151 50 10 0.2 0
EFNA1 EFNA1 P20827 Ephrin-A1 chr1 GO:0010975 Not Cancer Driver No 29 0.141 46 5 0.109 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0010975 Not Cancer Driver No 34 0.149 25 6 0.24 0
EFNB2_ENST00000245323 EFNB2 P52799 Ephrin-B2 chr13 GO:0010975 Not Cancer Driver No 42 0.126 97 15 0.155 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0010975 Not Cancer Driver No 45 0.132 183 22 0.12 0
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0010975 Not Cancer Driver No 104 0.115 382 43 0.113 0
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0010975 Not Cancer Driver No 118 0.306 117 34 0.291 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0010975 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0010975 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0010975 Not Cancer Driver No 186 0.176 119 17 0.143 7
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0010975 Census, Compendium Yes 120 0.161 284 44 0.155 11
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0010975 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO7 FBXO7 Q9Y3I1 F-box only protein 7 chr22 GO:0010975 Not Cancer Driver No 75 0.144 243 38 0.156 1
FBXW8 FBXW8 Q8N3Y1 F-box/WD repeat-containing protein 8 chr12 GO:0010975 Not Cancer Driver No 68 0.114 120 4 0.033 0
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0010975 Not Cancer Driver No 70 0.286 96 33 0.344 2
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0010975 Not Cancer Driver No 10 0.093 58 4 0.069 0
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 GO:0010975 Not Cancer Driver No 46 0.1 134 12 0.09 0
FLNA FLNA P21333 Filamin-A chrX GO:0010975 Census Yes 416 0.157 1456 214 0.147 28
FN1 FN1 P02751 Fibronectin chr2 GO:0010975 Compendium Yes 394 0.159 1243 185 0.149 8
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0010975 Not Cancer Driver No 147 0.206 256 59 0.23 25
FSTL4 FSTL4 Q6MZW2 Follistatin-related protein 4 chr5 GO:0010975 Not Cancer Driver No 134 0.159 96 12 0.125 0
GAK GAK O14976 Cyclin-G-associated kinase chr4 GO:0010975 Not Cancer Driver No 146 0.111 589 79 0.134 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0010975 Census, Compendium Yes 111 0.251 364 87 0.239 2
GDI1 GDI1 P31150 Rab GDP dissociation inhibitor alpha chrX GO:0010975 Not Cancer Driver No 69 0.154 34 6 0.176 2
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0010975 Not Cancer Driver No 65 0.15 288 42 0.146 62
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:0010975 Not Cancer Driver No 57 0.135 199 29 0.146 2
GOLGA4_ENST00000361924 GOLGA4 Q13439 Golgin subfamily A member 4 chr3 GO:0010975 Not Cancer Driver No 231 0.104 1658 162 0.098 0
GORASP1 GORASP1 Q9BQQ3 Golgi reassembly-stacking protein 1 chr3 GO:0010975 Not Cancer Driver No 49 0.111 293 32 0.109 0
GRID2 GRID2 O43424 Glutamate receptor ionotropic, delta-2 chr4 GO:0010975 Not Cancer Driver No 350 0.348 155 35 0.226 3
GRN GRN P28799 Progranulin chr17 GO:0010975 Not Cancer Driver No 76 0.128 29 6 0.207 1
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0010975 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0010975 Not Cancer Driver No 56 0.133 146 13 0.089 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0010975 Not Cancer Driver No 46 0.094 145 14 0.097 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0010975 Not Cancer Driver No 37 0.132 226 32 0.142 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0010975 Compendium Yes 233 0.32 43 16 0.372 0
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0010975 Not Cancer Driver No 20 0.129 17 6 0.353 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0010975 Not Cancer Driver No 183 0.134 265 37 0.14 6
IL1RAPL1 IL1RAPL1 Q9NZN1 Interleukin-1 receptor accessory protein-like 1 chrX GO:0010975 Not Cancer Driver No 205 0.295 77 19 0.247 0
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0010975 Not Cancer Driver No 138 0.122 394 45 0.114 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0010975 Not Cancer Driver No 102 0.101 629 42 0.067 0
ISLR2_ENST00000565159 ISLR2 Q6UXK2 Immunoglobulin superfamily containing leucine-rich repeat protein 2 chr15 GO:0010975 Not Cancer Driver No 128 0.172 344 49 0.142 0
IST1_ENST00000541571 IST1 P53990 IST1 homolog chr16 GO:0010975 Not Cancer Driver No 31 0.085 185 17 0.092 0
ITM2C ITM2C Q9NQX7 Integral membrane protein 2C chr2 GO:0010975 Not Cancer Driver No 31 0.116 33 4 0.121 0
ITPKA ITPKA P23677 Inositol-trisphosphate 3-kinase A chr15 GO:0010975 Not Cancer Driver No 28 0.061 216 7 0.032 0
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0010975 Not Cancer Driver No 183 0.135 804 100 0.124 0
KEL KEL P23276 Kell blood group glycoprotein chr7 GO:0010975 Compendium Yes 232 0.317 117 39 0.333 0
KHDC3L KHDC3L Q587J8 KH domain-containing protein 3 chr6 GO:0010975 Not Cancer Driver No 68 0.313 121 43 0.355 0
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0010975 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIF1A_ENST00000320389 KIF1A Q12756 Kinesin-like protein KIF1A chr2 GO:0010975 Not Cancer Driver No 275 0.163 594 79 0.133 35
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0010975 Not Cancer Driver No 62 0.254 28 12 0.429 0
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0010975 Not Cancer Driver No 65 0.25 76 15 0.197 0
KREMEN1_ENST00000407188 KREMEN1 Q96MU8 Kremen protein 1 chr22 GO:0010975 Not Cancer Driver No 68 0.144 73 7 0.096 1
L1CAM L1CAM P32004 Neural cell adhesion molecule L1 chrX GO:0010975 Not Cancer Driver No 228 0.181 442 75 0.17 54
LIMK1 LIMK1 P53667 LIM domain kinase 1 chr7 GO:0010975 Not Cancer Driver No 110 0.17 170 30 0.176 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0010975 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0010975 Not Cancer Driver No 65 0.184 9 0 0.0 0
LRIG2 LRIG2 O94898 Leucine-rich repeats and immunoglobulin-like domains protein 2 chr1 GO:0010975 Not Cancer Driver No 131 0.123 231 30 0.13 0
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0010975 Not Cancer Driver No 233 0.122 265 28 0.106 11
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0010975 Not Cancer Driver No 94 0.098 190 24 0.126 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0010975 Not Cancer Driver No 519 0.205 90 17 0.189 23
LZTS3_ENST00000329152 LZTS3 O60299 Leucine zipper putative tumor suppressor 3 chr20 GO:0010975 Not Cancer Driver No 72 0.107 569 62 0.109 0
MACF1_ENST00000372915 MACF1 Q9UPN3 Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 chr1 GO:0010975 Not Cancer Driver No 877 0.119 2826 334 0.118 4
MAG_ENST00000537831 MAG P20916 Myelin-associated glycoprotein chr19 GO:0010975 Not Cancer Driver No 118 0.188 65 7 0.108 1
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0010975 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0010975 Compendium Yes 367 0.201 1726 340 0.197 0
MAP2K1 MAP2K1 Q02750 Dual specificity mitogen-activated protein kinase kinase 1 chr15 GO:0010975 Census, Compendium Yes 94 0.239 96 24 0.25 6
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0010975 Census Yes 157 0.163 593 91 0.153 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0010975 Not Cancer Driver No 128 0.169 750 126 0.168 18
MARK1_ENST00000366917 MARK1 Q9P0L2 Serine/threonine-protein kinase MARK1 chr1 GO:0010975 Not Cancer Driver No 161 0.203 454 108 0.238 0
MBOAT1 MBOAT1 Q6ZNC8 Lysophospholipid acyltransferase 1 chr6 GO:0010975 Not Cancer Driver No 59 0.119 15 5 0.333 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0010975 Not Cancer Driver No 52 0.171 304 52 0.171 0
MCF2_ENST00000370576 MCF2 P10911 Proto-oncogene DBL chrX GO:0010975 Not Cancer Driver No 218 0.236 124 33 0.266 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0010975 Not Cancer Driver No 363 0.128 476 59 0.124 3
MINAR1 MINAR1 Q9UPX6 Major intrinsically disordered Notch2-binding receptor 1 chr15 GO:0010975 Not Cancer Driver No 171 0.187 584 104 0.178 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0010975 Not Cancer Driver No 7 0.103 0 0 0.0 0
MYLIP MYLIP Q8WY64 E3 ubiquitin-protein ligase MYLIP chr6 GO:0010975 Not Cancer Driver No 56 0.126 11 2 0.182 0
NCS1 NCS1 P62166 Neuronal calcium sensor 1 chr9 GO:0010975 Not Cancer Driver No 25 0.132 26 2 0.077 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0010975 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEFL NEFL P07196 Neurofilament light polypeptide chr8 GO:0010975 Not Cancer Driver No 92 0.169 285 39 0.137 12
NEU4_ENST00000407683 NEU4 Q8WWR8 Sialidase-4 chr2 GO:0010975 Not Cancer Driver No 82 0.169 199 37 0.186 0
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0010975 Not Cancer Driver No 155 0.172 685 120 0.175 0
NGEF NGEF Q8N5V2 Ephexin-1 chr2 GO:0010975 Not Cancer Driver No 125 0.176 296 34 0.115 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0010975 Not Cancer Driver No 66 0.274 93 25 0.269 1
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0010975 Not Cancer Driver No 214 0.248 248 61 0.246 4
NR2F1_ENST00000327111 NR2F1 P10589 COUP transcription factor 1 chr5 GO:0010975 Not Cancer Driver No 67 0.158 110 6 0.055 4
NRCAM_ENST00000425651 NRCAM Q92823 Neuronal cell adhesion molecule chr7 GO:0010975 Not Cancer Driver No 210 0.161 471 75 0.159 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0010975 Compendium Yes 146 0.158 211 31 0.147 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0010975 Not Cancer Driver No 57 0.094 66 4 0.061 2
NTNG1_ENST00000370073 NTNG1 Q9Y2I2 Netrin-G1 chr1 GO:0010975 Not Cancer Driver No 149 0.276 1 0 0.0 0
NTNG2 NTNG2 Q96CW9 Netrin-G2 chr9 GO:0010975 Not Cancer Driver No 91 0.172 8 4 0.5 7
OBSL1 OBSL1 O75147 Obscurin-like protein 1 chr2 GO:0010975 Not Cancer Driver No 233 0.123 553 60 0.108 0
PACSIN1_ENST00000244458 PACSIN1 Q9BY11 Protein kinase C and casein kinase substrate in neurons protein 1 chr6 GO:0010975 Not Cancer Driver No 56 0.126 318 47 0.148 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0010975 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0010975 Not Cancer Driver No 127 0.227 286 64 0.224 2
PAQR3 PAQR3 Q6TCH7 Progestin and adipoQ receptor family member 3 chr4 GO:0010975 Not Cancer Driver No 38 0.122 0 0 0.0 0
PARP6 PARP6 Q2NL67 Protein mono-ADP-ribosyltransferase PARP6 chr15 GO:0010975 Not Cancer Driver No 87 0.138 67 13 0.194 0
PDLIM5_ENST00000317968 PDLIM5 Q96HC4 PDZ and LIM domain protein 5 chr4 GO:0010975 Not Cancer Driver No 89 0.149 372 57 0.153 0
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX GO:0010975 Not Cancer Driver No 243 0.13 199 34 0.171 0
PMP22_ENST00000612492 PMP22 Q01453 Peripheral myelin protein 22 chr17 GO:0010975 Not Cancer Driver No 20 0.125 0 0 0.0 37
POU4F2 POU4F2 Q12837 POU domain, class 4, transcription factor 2 chr4 GO:0010975 Not Cancer Driver No 130 0.318 308 87 0.282 0
PPFIA2 PPFIA2 O75334 Liprin-alpha-2 chr12 GO:0010975 Not Cancer Driver No 342 0.272 936 263 0.281 0
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0010975 Compendium Yes 85 0.163 140 27 0.193 7
PRAG1_ENST00000622241 PRAG1 Q86YV5 Inactive tyrosine-protein kinase PRAG1 chr8 GO:0010975 Not Cancer Driver No 193 0.137 988 150 0.152 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0010975 Census, Compendium Yes 69 0.282 205 49 0.239 1
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0010975 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0010975 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTN PTN P21246 Pleiotrophin chr7 GO:0010975 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPN9 PTPN9 P43378 Tyrosine-protein phosphatase non-receptor type 9 chr15 GO:0010975 Not Cancer Driver No 77 0.13 78 5 0.064 0
PTPRD PTPRD P23468 Receptor-type tyrosine-protein phosphatase delta chr9 GO:0010975 Census, Compendium Yes 577 0.302 747 219 0.293 0
PTPRF PTPRF P10586 Receptor-type tyrosine-protein phosphatase F chr1 GO:0010975 Not Cancer Driver No 268 0.141 696 96 0.138 0
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 GO:0010975 Not Cancer Driver No 212 0.147 465 61 0.131 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0010975 Not Cancer Driver No 204 0.168 137 34 0.248 0
PTPRS PTPRS Q13332 Receptor-type tyrosine-protein phosphatase S chr19 GO:0010975 Not Cancer Driver No 250 0.128 829 111 0.134 0
RAB11A RAB11A P62491 Ras-related protein Rab-11A chr15 GO:0010975 Not Cancer Driver No 31 0.144 43 4 0.093 0
RAB21 RAB21 Q9UL25 Ras-related protein Rab-21 chr12 GO:0010975 Not Cancer Driver No 23 0.102 59 4 0.068 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0010975 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0010975 Not Cancer Driver No 216 0.144 803 116 0.144 0
RELN RELN P78509 Reelin chr7 GO:0010975 Not Cancer Driver No 761 0.22 107 19 0.178 7
RGMA_ENST00000329082 RGMA Q96B86 Repulsive guidance molecule A chr15 GO:0010975 Not Cancer Driver No 63 0.14 105 13 0.124 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0010975 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:0010975 Not Cancer Driver No 74 0.341 29 11 0.379 0
RND2 RND2 P52198 Rho-related GTP-binding protein RhoN chr17 GO:0010975 Not Cancer Driver No 19 0.084 54 4 0.074 0
RNF6 RNF6 Q9Y252 E3 ubiquitin-protein ligase RNF6 chr13 GO:0010975 Compendium Yes 91 0.133 601 87 0.145 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0010975 Not Cancer Driver No 121 0.102 866 82 0.095 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0010975 Not Cancer Driver No 38 0.08 148 17 0.115 5
RTN4RL1 RTN4RL1 Q86UN2 Reticulon-4 receptor-like 1 chr17 GO:0010975 Not Cancer Driver No 56 0.127 142 12 0.085 0
RTN4RL2 RTN4RL2 Q86UN3 Reticulon-4 receptor-like 2 chr11 GO:0010975 Not Cancer Driver No 38 0.09 121 5 0.041 0
RUFY3_ENST00000226328 RUFY3 Q7L099 Protein RUFY3 chr4 GO:0010975 Not Cancer Driver No 75 0.16 204 29 0.142 0
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0010975 Not Cancer Driver No 55 0.091 85 4 0.047 0
SCARF1 SCARF1 Q14162 Scavenger receptor class F member 1 chr17 GO:0010975 Not Cancer Driver No 90 0.108 340 61 0.179 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0010975 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA3B_ENST00000616701 SEMA3B Q13214 Semaphorin-3B chr3 GO:0010975 Not Cancer Driver No 46 0.061 145 8 0.055 0
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 GO:0010975 Not Cancer Driver No 136 0.181 111 23 0.207 0
SEMA3D SEMA3D O95025 Semaphorin-3D chr7 GO:0010975 Not Cancer Driver No 191 0.246 101 44 0.436 0
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0010975 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA3F SEMA3F Q13275 Semaphorin-3F chr3 GO:0010975 Not Cancer Driver No 114 0.145 194 27 0.139 0
SEMA3G SEMA3G Q9NS98 Semaphorin-3G chr3 GO:0010975 Not Cancer Driver No 104 0.133 206 28 0.136 0
SEMA4A_ENST00000355014 SEMA4A Q9H3S1 Semaphorin-4A chr1 GO:0010975 Not Cancer Driver No 123 0.162 122 26 0.213 4
SEMA4B SEMA4B Q9NPR2 Semaphorin-4B chr15 GO:0010975 Not Cancer Driver No 94 0.112 107 17 0.159 0
SEMA4C SEMA4C Q9C0C4 Semaphorin-4C chr2 GO:0010975 Not Cancer Driver No 111 0.133 149 27 0.181 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0010975 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA4F SEMA4F O95754 Semaphorin-4F chr2 GO:0010975 Not Cancer Driver No 113 0.147 140 16 0.114 0
SEMA4G_ENST00000370250 SEMA4G Q9NTN9 Semaphorin-4G chr10 GO:0010975 Not Cancer Driver No 95 0.113 285 30 0.105 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0010975 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA5B_ENST00000616742 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0010975 Not Cancer Driver No 229 0.199 162 16 0.099 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0010975 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0010975 Not Cancer Driver No 77 0.087 340 26 0.076 0
SEMA6C SEMA6C Q9H3T2 Semaphorin-6C chr1 GO:0010975 Not Cancer Driver No 116 0.125 411 27 0.066 0
SEMA6D_ENST00000536845 SEMA6D Q8NFY4 Semaphorin-6D chr15 GO:0010975 Not Cancer Driver No 212 0.198 475 99 0.208 0
SEMA7A SEMA7A O75326 Semaphorin-7A chr15 GO:0010975 Not Cancer Driver No 81 0.122 150 21 0.14 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0010975 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0010975 Not Cancer Driver No 47 0.159 1 0 0.0 0
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0010975 Census Yes 68 0.108 470 52 0.111 0
SIPA1L1 SIPA1L1 O43166 Signal-induced proliferation-associated 1-like protein 1 chr14 GO:0010975 Not Cancer Driver No 321 0.178 1175 226 0.192 0
SLC39A12 SLC39A12 Q504Y0 Zinc transporter ZIP12 chr10 GO:0010975 Not Cancer Driver No 210 0.304 89 29 0.326 0
SLIT1 SLIT1 O75093 Slit homolog 1 protein chr10 GO:0010975 Not Cancer Driver No 221 0.144 36 1 0.028 0
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 GO:0010975 Not Cancer Driver No 61 0.296 176 49 0.278 1
SNAPIN SNAPIN O95295 SNARE-associated protein Snapin chr1 GO:0010975 Not Cancer Driver No 9 0.066 62 5 0.081 0
SPART_ENST00000355182 SPART Q8N0X7 Spartin chr13 GO:0010975 Not Cancer Driver No 112 0.168 396 68 0.172 1
SPOCK1 SPOCK1 Q08629 Testican-1 chr5 GO:0010975 Not Cancer Driver No 82 0.187 107 16 0.15 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0010975 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRF SRF P11831 Serum response factor chr6 GO:0010975 Not Cancer Driver No 44 0.087 443 42 0.095 0
SS18L1 SS18L1 O75177 Calcium-responsive transactivator chr20 GO:0010975 Census Yes 53 0.134 356 48 0.135 0
SS18L2 SS18L2 Q9UHA2 SS18-like protein 2 chr3 GO:0010975 Not Cancer Driver No 4 0.052 7 1 0.143 0
STAU2 STAU2 Q9NUL3 Double-stranded RNA-binding protein Staufen homolog 2 chr8 GO:0010975 Not Cancer Driver No 68 0.119 486 54 0.111 0
STK24 STK24 Q9Y6E0 Serine/threonine-protein kinase 24 chr13 GO:0010975 Not Cancer Driver No 67 0.151 118 16 0.136 0
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0010975 Not Cancer Driver No 34 0.19 122 23 0.189 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0010975 Not Cancer Driver No 38 0.132 155 20 0.129 2
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0010975 Not Cancer Driver No 153 0.114 830 90 0.108 2
TANC2 TANC2 Q9HCD6 Protein TANC2 chr17 GO:0010975 Not Cancer Driver No 278 0.14 999 127 0.127 1
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 GO:0010975 Not Cancer Driver No 88 0.129 413 56 0.136 5
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0010975 Not Cancer Driver No 44 0.101 253 25 0.099 0
THY1 THY1 P04216 Thy-1 membrane glycoprotein chr11 GO:0010975 Not Cancer Driver No 24 0.149 5 0 0.0 0
TLX2 TLX2 O43763 T-cell leukemia homeobox protein 2 chr2 GO:0010975 Not Cancer Driver No 24 0.085 220 15 0.068 0
TMEM106B TMEM106B Q9NUM4 Transmembrane protein 106B chr7 GO:0010975 Not Cancer Driver No 31 0.113 56 4 0.071 1
TNR TNR Q92752 Tenascin-R chr1 GO:0010975 Not Cancer Driver No 496 0.365 358 128 0.358 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0010975 Not Cancer Driver No 115 0.152 173 30 0.173 0
TRPC5 TRPC5 Q9UL62 Short transient receptor potential channel 5 chrX GO:0010975 Not Cancer Driver No 255 0.262 148 32 0.216 0
TRPV2 TRPV2 Q9Y5S1 Transient receptor potential cation channel subfamily V member 2 chr17 GO:0010975 Not Cancer Driver No 105 0.137 175 23 0.131 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0010975 Not Cancer Driver No 142 0.163 231 34 0.147 44
TSC1 TSC1 Q92574 Hamartin chr9 GO:0010975 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0010975 Not Cancer Driver No 53 0.15 44 6 0.136 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0010975 Not Cancer Driver No 34 0.097 59 8 0.136 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0010975 Not Cancer Driver No 141 0.161 136 22 0.162 0
ULK1 ULK1 O75385 Serine/threonine-protein kinase ULK1 chr12 GO:0010975 Not Cancer Driver No 142 0.135 588 77 0.131 0
ULK2_ENST00000361658 ULK2 Q8IYT8 Serine/threonine-protein kinase ULK2 chr17 GO:0010975 Not Cancer Driver No 132 0.127 519 84 0.162 0
ULK4 ULK4 Q96C45 Serine/threonine-protein kinase ULK4 chr3 GO:0010975 Not Cancer Driver No 162 0.127 180 33 0.183 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0010975 Not Cancer Driver No 27 0.116 41 7 0.171 0
VIM_ENST00000224237 VIM P08670 Vimentin chr10 GO:0010975 Not Cancer Driver No 84 0.18 316 57 0.18 1
VLDLR VLDLR P98155 Very low-density lipoprotein receptor chr9 GO:0010975 Not Cancer Driver No 90 0.103 55 3 0.055 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0010975 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0010975 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0010975 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0010975 Not Cancer Driver No 93 0.266 18 9 0.5 4
XK XK P51811 Endoplasmic reticulum membrane adapter protein XK chrX GO:0010975 Not Cancer Driver No 86 0.194 32 6 0.188 3
YWHAH YWHAH Q04917 14-3-3 protein eta chr22 GO:0010975 Not Cancer Driver No 15 0.061 55 3 0.055 0
ZDHHC15 ZDHHC15 Q96MV8 Palmitoyltransferase ZDHHC15 chrX GO:0010975 Not Cancer Driver No 81 0.24 45 9 0.2 0
ZFYVE27_ENST00000393677 ZFYVE27 Q5T4F4 Protrudin chr10 GO:0010975 Not Cancer Driver No 45 0.109 140 22 0.157 1
ZNF804A ZNF804A Q7Z570 Zinc finger protein 804A chr2 GO:0010975 Not Cancer Driver No 506 0.419 687 307 0.447 0