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Total number of protein in "GO:0010906" GO term:  114

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACACB_ENST00000377848 ACACB O00763 Acetyl-CoA carboxylase 2 chr12 GO:0010906 Not Cancer Driver No 388 0.158 342 62 0.181 0
ACADM_ENST00000370841 ACADM P11310 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial chr1 GO:0010906 Not Cancer Driver No 61 0.145 41 5 0.122 19
ACTN3_ENST00000513398 ACTN3 Q08043 Alpha-actinin-3 chr11 GO:0010906 Not Cancer Driver No 123 0.137 135 13 0.096 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0010906 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0010906 Not Cancer Driver No 63 0.168 69 10 0.145 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0010906 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0010906 Census Yes 77 0.16 84 9 0.107 2
ARPP19_ENST00000567669 ARPP19 P56211 cAMP-regulated phosphoprotein 19 chr15 GO:0010906 Not Cancer Driver No 17 0.152 112 17 0.152 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0010906 Not Cancer Driver No 14 0.083 163 14 0.086 0
BCKDK BCKDK O14874 [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial chr16 GO:0010906 Not Cancer Driver No 62 0.15 39 3 0.077 3
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0010906 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 GO:0010906 Not Cancer Driver No 61 0.217 96 17 0.177 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0010906 Not Cancer Driver No 42 0.171 73 14 0.192 0
CLK2 CLK2 P49760 Dual specificity protein kinase CLK2 chr1 GO:0010906 Not Cancer Driver No 104 0.208 151 37 0.245 0
COX11 COX11 Q9Y6N1 Cytochrome c oxidase assembly protein COX11, mitochondrial chr17 GO:0010906 Not Cancer Driver No 21 0.076 51 4 0.078 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0010906 Not Cancer Driver No 76 0.13 91 5 0.055 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0010906 Not Cancer Driver No 126 0.111 50 8 0.16 4
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0010906 Not Cancer Driver No 56 0.144 17 2 0.118 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0010906 Not Cancer Driver No 56 0.059 264 11 0.042 0
DUSP12 DUSP12 Q9UNI6 Dual specificity protein phosphatase 12 chr1 GO:0010906 Not Cancer Driver No 33 0.097 30 1 0.033 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0010906 Not Cancer Driver No 77 0.128 294 39 0.133 0
ENPP1 ENPP1 P22413 Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 chr6 GO:0010906 Not Cancer Driver No 148 0.16 101 5 0.05 33
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0010906 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPM2AIP1 EPM2AIP1 Q7L775 EPM2A-interacting protein 1 chr3 GO:0010906 Not Cancer Driver No 61 0.1 22 1 0.045 0
ERFE ERFE Q4G0M1 Erythroferrone chr2 GO:0010906 Not Cancer Driver No 4 0.011 179 0 0.0 0
FAM3A_ENST00000447601 FAM3A P98173 Protein FAM3A chrX GO:0010906 Not Cancer Driver No 27 0.117 48 9 0.188 0
FAM3C FAM3C Q92520 Protein FAM3C chr7 GO:0010906 Not Cancer Driver No 25 0.11 33 3 0.091 0
FBP1_ENST00000375326 FBP1 P09467 Fructose-1,6-bisphosphatase 1 chr9 GO:0010906 Not Cancer Driver No 33 0.098 19 0 0.0 4
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0010906 Compendium Yes 70 0.153 258 34 0.132 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 GO:0010906 Not Cancer Driver No 97 0.132 511 65 0.127 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0010906 Not Cancer Driver No 79 0.12 548 64 0.117 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0010906 Census, Compendium Yes 81 0.124 584 75 0.128 0
GCG GCG P01275 Pro-glucagon chr2 GO:0010906 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCGR GCGR P47871 Glucagon receptor chr17 GO:0010906 Not Cancer Driver No 16 0.034 56 2 0.036 4
GCKR GCKR Q14397 Glucokinase regulatory protein chr2 GO:0010906 Not Cancer Driver No 98 0.157 85 27 0.318 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0010906 Not Cancer Driver No 88 0.189 73 14 0.192 107
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 GO:0010906 Not Cancer Driver No 51 0.15 13 1 0.077 0
GNMT GNMT Q14749 Glycine N-methyltransferase chr6 GO:0010906 Not Cancer Driver No 25 0.085 0 0 0.0 3
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0010906 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPT_ENST00000528431 GPT P24298 Alanine aminotransferase 1 chr8 GO:0010906 Not Cancer Driver No 52 0.105 51 9 0.176 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0010906 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSK3B_ENST00000264235 GSK3B P49841 Glycogen synthase kinase-3 beta chr3 GO:0010906 Not Cancer Driver No 56 0.133 146 13 0.089 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0010906 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0010906 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0010906 Not Cancer Driver No 24 0.093 106 17 0.16 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0010906 Not Cancer Driver No 42 0.094 34 2 0.059 7
INS INS P01308 Insulin chr11 GO:0010906 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSR INSR P06213 Insulin receptor chr19 GO:0010906 Not Cancer Driver No 190 0.137 280 57 0.204 64
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0010906 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0010906 Not Cancer Driver No 69 0.052 1112 57 0.051 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0010906 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0010906 Not Cancer Driver No 107 0.129 266 27 0.102 0
KHK_ENST00000260598 KHK P50053 Ketohexokinase chr2 GO:0010906 Not Cancer Driver No 38 0.128 42 4 0.095 2
LCMT1 LCMT1 Q9UIC8 Leucine carboxyl methyltransferase 1 chr16 GO:0010906 Not Cancer Driver No 43 0.129 2 0 0.0 0
LEP LEP P41159 Leptin chr7 GO:0010906 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0010906 Not Cancer Driver No 243 0.209 57 11 0.193 0
MIDN MIDN Q504T8 Midnolin chr19 GO:0010906 Not Cancer Driver No 43 0.092 446 43 0.096 0
MLYCD MLYCD O95822 Malonyl-CoA decarboxylase, mitochondrial chr16 GO:0010906 Not Cancer Driver No 41 0.083 82 0 0.0 0
MST1 MST1 P26927 Hepatocyte growth factor-like protein chr3 GO:0010906 Not Cancer Driver No 110 0.155 168 19 0.113 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0010906 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NLN NLN Q9BYT8 Neurolysin, mitochondrial chr5 GO:0010906 Not Cancer Driver No 70 0.099 25 3 0.12 0
NNMT NNMT P40261 Nicotinamide N-methyltransferase chr11 GO:0010906 Not Cancer Driver No 51 0.193 5 1 0.2 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0010906 Not Cancer Driver No 156 0.149 89 16 0.18 2
PASK_ENST00000234040 PASK Q96RG2 PAS domain-containing serine/threonine-protein kinase chr2 GO:0010906 Not Cancer Driver No 181 0.137 412 62 0.15 0
PDK1_ENST00000282077 PDK1 Q15118 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial chr2 GO:0010906 Not Cancer Driver No 52 0.119 50 10 0.2 0
PDK2 PDK2 Q15119 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial chr17 GO:0010906 Not Cancer Driver No 45 0.111 35 4 0.114 0
PDK3_ENST00000379162 PDK3 Q15120 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial chrX GO:0010906 Not Cancer Driver No 61 0.15 28 6 0.214 1
PDK4 PDK4 Q16654 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial chr7 GO:0010906 Not Cancer Driver No 70 0.17 14 2 0.143 0
PFKFB1 PFKFB1 P16118 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 chrX GO:0010906 Not Cancer Driver No 81 0.172 48 11 0.229 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0010906 Not Cancer Driver No 68 0.135 97 18 0.186 0
PGP PGP A6NDG6 Glycerol-3-phosphate phosphatase chr16 GO:0010906 Not Cancer Driver No 10 0.031 21 0 0.0 0
PHKG2 PHKG2 P15735 Phosphorylase b kinase gamma catalytic chain, liver/testis isoform chr16 GO:0010906 Not Cancer Driver No 48 0.118 50 6 0.12 4
PHLDA2_ENST00000645523 PHLDA2 Q53GA4 Pleckstrin homology-like domain family A member 2 chr11 GO:0010906 Not Cancer Driver No 12 0.079 58 2 0.034 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0010906 Not Cancer Driver No 2 0.037 23 1 0.043 0
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0010906 Not Cancer Driver No 50 0.187 198 38 0.192 0
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0010906 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPARGC1A PPARGC1A Q9UBK2 Peroxisome proliferator-activated receptor gamma coactivator 1-alpha chr4 GO:0010906 Not Cancer Driver No 181 0.227 609 148 0.243 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0010906 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:0010906 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1R3A PPP1R3A Q16821 Protein phosphatase 1 regulatory subunit 3A chr7 GO:0010906 Not Cancer Driver No 430 0.383 807 334 0.414 1
PPP1R3B PPP1R3B Q86XI6 Protein phosphatase 1 regulatory subunit 3B chr8 GO:0010906 Not Cancer Driver No 36 0.126 19 2 0.105 0
PPP1R3C PPP1R3C Q9UQK1 Protein phosphatase 1 regulatory subunit 3C chr10 GO:0010906 Not Cancer Driver No 37 0.117 16 0 0.0 0
PPP1R3D PPP1R3D O95685 Protein phosphatase 1 regulatory subunit 3D chr20 GO:0010906 Not Cancer Driver No 36 0.12 94 8 0.085 0
PPP1R3E PPP1R3E Q9H7J1 Protein phosphatase 1 regulatory subunit 3E chr14 GO:0010906 Not Cancer Driver No 1 0.004 182 0 0.0 0
PPP1R3F PPP1R3F Q6ZSY5 Protein phosphatase 1 regulatory subunit 3F chrX GO:0010906 Not Cancer Driver No 79 0.099 636 64 0.101 0
PPP1R3G PPP1R3G B7ZBB8 Protein phosphatase 1 regulatory subunit 3G chr6 GO:0010906 Not Cancer Driver No 14 0.039 198 11 0.056 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0010906 Not Cancer Driver No 100 0.118 240 33 0.138 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0010906 Not Cancer Driver No 110 0.237 78 15 0.192 31
PTH PTH P01270 Parathyroid hormone chr11 GO:0010906 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0010906 Not Cancer Driver No 57 0.137 120 14 0.117 0
RANBP2 RANBP2 P49792 E3 SUMO-protein ligase RanBP2 chr2 GO:0010906 Census, Compendium Yes 427 0.132 1387 177 0.128 3
RGN RGN Q15493 Regucalcin chrX GO:0010906 Not Cancer Driver No 38 0.127 14 3 0.214 0
RORA_ENST00000335670 RORA P35398 Nuclear receptor ROR-alpha chr15 GO:0010906 Not Cancer Driver No 57 0.109 182 17 0.093 4
RORC RORC P51449 Nuclear receptor ROR-gamma chr1 GO:0010906 Not Cancer Driver No 96 0.185 187 36 0.193 1
RUBCNL_ENST00000389908 RUBCNL Q9H714 Protein associated with UVRAG as autophagy enhancer chr13 GO:0010906 Not Cancer Driver No 92 0.139 219 32 0.146 0
SDHAF3 SDHAF3 Q9NRP4 Succinate dehydrogenase assembly factor 3, mitochondrial chr7 GO:0010906 Not Cancer Driver No 18 0.144 65 5 0.077 0
SELENOS SELENOS Q9BQE4 Selenoprotein S chr15 GO:0010906 Not Cancer Driver No 7 0.037 122 6 0.049 0
SERPINA12 SERPINA12 Q8IW75 Serpin A12 chr14 GO:0010906 Not Cancer Driver No 90 0.217 22 3 0.136 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0010906 Not Cancer Driver No 74 0.154 147 26 0.177 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0010906 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0010906 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0010906 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLC25A12 SLC25A12 O75746 Calcium-binding mitochondrial carrier protein Aralar1 chr2 GO:0010906 Not Cancer Driver No 110 0.162 21 7 0.333 2
SLC35B4 SLC35B4 Q969S0 UDP-xylose and UDP-N-acetylglucosamine transporter chr7 GO:0010906 Not Cancer Driver No 27 0.082 10 1 0.1 0
SLC45A3 SLC45A3 Q96JT2 Solute carrier family 45 member 3 chr1 GO:0010906 Census, Compendium Yes 75 0.136 25 6 0.24 0
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0010906 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0010906 Census Yes 53 0.099 130 11 0.085 1
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0010906 Census, Compendium Yes 75 0.173 135 14 0.104 9
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0010906 Not Cancer Driver No 44 0.163 39 9 0.231 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0010906 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0010906 Not Cancer Driver No 170 0.154 215 45 0.209 0
WDR5 WDR5 P61964 WD repeat-containing protein 5 chr9 GO:0010906 Not Cancer Driver No 30 0.09 35 3 0.086 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0010906 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF692_ENST00000306601 ZNF692 Q9BU19 Zinc finger protein 692 chr1 GO:0010906 Not Cancer Driver No 70 0.135 302 42 0.139 0