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Total number of protein in "GO:0010817" GO term:  420

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AACS AACS Q86V21 Acetoacetyl-CoA synthetase chr12 GO:0010817 Not Cancer Driver No 92 0.137 16 0 0.0 0
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0010817 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0010817 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0010817 Not Cancer Driver No 511 0.197 136 23 0.169 14
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0010817 Not Cancer Driver No 255 0.161 138 23 0.167 97
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0010817 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0010817 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACSL4_ENST00000469796 ACSL4 O60488 Long-chain-fatty-acid--CoA ligase 4 chrX GO:0010817 Not Cancer Driver No 97 0.136 77 12 0.156 1
ACVR1C ACVR1C Q8NER5 Activin receptor type-1C chr2 GO:0010817 Not Cancer Driver No 90 0.183 3 1 0.333 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0010817 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0010817 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADCYAP1_ENST00000450565 ADCYAP1 P18509 Pituitary adenylate cyclase-activating polypeptide chr18 GO:0010817 Not Cancer Driver No 43 0.244 75 11 0.147 0
ADH1A ADH1A P07327 Alcohol dehydrogenase 1A chr4 GO:0010817 Not Cancer Driver No 73 0.195 6 3 0.5 0
ADH1B ADH1B P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B chr4 GO:0010817 Not Cancer Driver No 108 0.288 6 4 0.667 0
ADH1C ADH1C P00326 Alcohol dehydrogenase 1C chr4 GO:0010817 Not Cancer Driver No 116 0.309 6 5 0.833 0
ADH4_ENST00000265512 ADH4 P08319 All-trans-retinol dehydrogenase [NAD(+)] ADH4 chr4 GO:0010817 Not Cancer Driver No 49 0.129 5 1 0.2 0
ADH6_ENST00000237653 ADH6 P28332 Alcohol dehydrogenase 6 chr4 GO:0010817 Not Cancer Driver No 71 0.193 0 0 0.0 0
ADH7_ENST00000209665 ADH7 P40394 All-trans-retinol dehydrogenase [NAD(+)] ADH7 chr4 GO:0010817 Not Cancer Driver No 74 0.192 15 2 0.133 0
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0010817 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADM ADM P35318 Pro-adrenomedullin chr11 GO:0010817 Not Cancer Driver No 20 0.108 113 13 0.115 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0010817 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0010817 Not Cancer Driver No 67 0.144 161 10 0.062 0
AFP AFP P02771 Alpha-fetoprotein chr4 GO:0010817 Not Cancer Driver No 107 0.176 24 5 0.208 0
AGT AGT P01019 Angiotensinogen chr1 GO:0010817 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTR1_ENST00000349243 AGTR1 P30556 Type-1 angiotensin II receptor chr3 GO:0010817 Not Cancer Driver No 95 0.265 0 0 0.0 1
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 GO:0010817 Not Cancer Driver No 31 0.099 161 19 0.118 0
AKR1B1 AKR1B1 P15121 Aldo-keto reductase family 1 member B1 chr7 GO:0010817 Not Cancer Driver No 52 0.165 19 1 0.053 0
AKR1B10 AKR1B10 O60218 Aldo-keto reductase family 1 member B10 chr7 GO:0010817 Not Cancer Driver No 58 0.184 28 4 0.143 0
AKR1C1 AKR1C1 Q04828 Aldo-keto reductase family 1 member C1 chr10 GO:0010817 Not Cancer Driver No 56 0.173 1 0 0.0 0
AKR1C2 AKR1C2 P52895 Aldo-keto reductase family 1 member C2 chr10 GO:0010817 Not Cancer Driver No 32 0.099 1 0 0.0 4
AKR1C3 AKR1C3 P42330 Aldo-keto reductase family 1 member C3 chr10 GO:0010817 Not Cancer Driver No 49 0.152 11 1 0.091 0
AKR1C4 AKR1C4 P17516 Aldo-keto reductase family 1 member C4 chr10 GO:0010817 Not Cancer Driver No 78 0.241 9 3 0.333 0
AKR1D1 AKR1D1 P51857 Aldo-keto reductase family 1 member D1 chr7 GO:0010817 Not Cancer Driver No 89 0.273 15 3 0.2 5
ALDH1A1 ALDH1A1 P00352 Aldehyde dehydrogenase 1A1 chr9 GO:0010817 Not Cancer Driver No 65 0.13 29 3 0.103 0
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0010817 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALDH1A3 ALDH1A3 P47895 Aldehyde dehydrogenase family 1 member A3 chr15 GO:0010817 Not Cancer Driver No 74 0.145 73 7 0.096 10
ALDH8A1 ALDH8A1 Q9H2A2 2-aminomuconic semialdehyde dehydrogenase chr6 GO:0010817 Not Cancer Driver No 107 0.22 40 6 0.15 0
ALDH9A1 ALDH9A1 P49189 4-trimethylaminobutyraldehyde dehydrogenase chr1 GO:0010817 Not Cancer Driver No 57 0.115 16 0 0.0 0
ANO1 ANO1 Q5XXA6 Anoctamin-1 chr11 GO:0010817 Not Cancer Driver No 155 0.157 168 14 0.083 0
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0010817 Not Cancer Driver No 59 0.171 61 12 0.197 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0010817 Census Yes 77 0.098 511 56 0.11 0
ASMT_ENST00000381229 ASMT P46597 Acetylserotonin O-methyltransferase chrX GO:0010817 Not Cancer Driver No 67 0.194 1 0 0.0 0
ATP1A1_ENST00000295598 ATP1A1 P05023 Sodium/potassium-transporting ATPase subunit alpha-1 chr1 GO:0010817 Census Yes 115 0.112 115 16 0.139 6
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX GO:0010817 Not Cancer Driver No 56 0.16 0 0 0.0 2
AWAT2 AWAT2 Q6E213 Acyl-CoA wax alcohol acyltransferase 2 chrX GO:0010817 Not Cancer Driver No 58 0.174 4 0 0.0 0
BACE2 BACE2 Q9Y5Z0 Beta-secretase 2 chr21 GO:0010817 Not Cancer Driver No 61 0.118 23 2 0.087 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0010817 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP3 BAIAP3 O94812 BAI1-associated protein 3 chr16 GO:0010817 Not Cancer Driver No 170 0.143 230 35 0.152 0
BCAT2 BCAT2 O15382 Branched-chain-amino-acid aminotransferase, mitochondrial chr19 GO:0010817 Not Cancer Driver No 54 0.138 19 0 0.0 2
BCHE BCHE P06276 Cholinesterase chr3 GO:0010817 Not Cancer Driver No 185 0.307 14 4 0.286 38
BCO1 BCO1 Q9HAY6 Beta,beta-carotene 15,15'-dioxygenase chr16 GO:0010817 Not Cancer Driver No 78 0.143 37 5 0.135 1
BCO2 BCO2 Q9BYV7 Carotenoid-cleaving dioxygenase, mitochondrial chr11 GO:0010817 Not Cancer Driver No 79 0.136 14 1 0.071 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0010817 Not Cancer Driver No 94 0.186 75 21 0.28 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0010817 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0010817 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0010817 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0010817 Not Cancer Driver No 26 0.065 93 2 0.022 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0010817 Not Cancer Driver No 90 0.122 321 39 0.121 0
BTK_ENST00000308731 BTK Q06187 Tyrosine-protein kinase BTK chrX GO:0010817 Census, Compendium Yes 147 0.223 114 27 0.237 110
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0010817 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 GO:0010817 Not Cancer Driver No 61 0.217 96 17 0.177 0
C1QTNF3_ENST00000231338 C1QTNF3 Q9BXJ4 Complement C1q tumor necrosis factor-related protein 3 chr5 GO:0010817 Not Cancer Driver No 42 0.171 73 14 0.192 0
C2CD2L C2CD2L O14523 Phospholipid transfer protein C2CD2L chr11 GO:0010817 Not Cancer Driver No 77 0.109 491 65 0.132 0
CACNA1H CACNA1H O95180 Voltage-dependent T-type calcium channel subunit alpha-1H chr16 GO:0010817 Not Cancer Driver No 323 0.137 1045 141 0.135 18
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0010817 Not Cancer Driver No 87 0.129 52 6 0.115 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0010817 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0010817 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCDC186 CCDC186 Q7Z3E2 Coiled-coil domain-containing protein 186 chr10 GO:0010817 Not Cancer Driver No 99 0.11 702 80 0.114 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0010817 Not Cancer Driver No 66 0.185 19 1 0.053 0
CD38 CD38 P28907 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 chr4 GO:0010817 Not Cancer Driver No 54 0.18 3 1 0.333 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:0010817 Not Cancer Driver No 55 0.111 139 30 0.216 0
CFTR CFTR P13569 Cystic fibrosis transmembrane conductance regulator chr7 GO:0010817 Not Cancer Driver No 287 0.194 145 18 0.124 151
CGA_ENST00000627148 CGA P01215 Glycoprotein hormones alpha chain chr6 GO:0010817 Not Cancer Driver No 28 0.241 0 0 0.0 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0010817 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CHGA CHGA P10645 Chromogranin-A chr14 GO:0010817 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHST10_ENST00000409701 CHST10 O43529 Carbohydrate sulfotransferase 10 chr2 GO:0010817 Not Cancer Driver No 59 0.166 15 1 0.067 0
CLCN2 CLCN2 P51788 Chloride channel protein 2 chr3 GO:0010817 Not Cancer Driver No 124 0.138 224 38 0.17 8
CLTRN CLTRN Q9HBJ8 Collectrin chrX GO:0010817 Not Cancer Driver No 28 0.126 28 4 0.143 0
CMA1 CMA1 P23946 Chymase chr14 GO:0010817 Not Cancer Driver No 47 0.19 9 1 0.111 0
CORIN CORIN Q9Y5Q5 Atrial natriuretic peptide-converting enzyme chr4 GO:0010817 Not Cancer Driver No 208 0.2 60 13 0.217 2
CPA3 CPA3 P15088 Mast cell carboxypeptidase A chr3 GO:0010817 Not Cancer Driver No 111 0.266 38 9 0.237 0
CPE CPE P16870 Carboxypeptidase E chr4 GO:0010817 Not Cancer Driver No 98 0.206 127 24 0.189 0
CPQ CPQ Q9Y646 Carboxypeptidase Q chr8 GO:0010817 Not Cancer Driver No 110 0.233 3 0 0.0 0
CRABP1 CRABP1 P29762 Cellular retinoic acid-binding protein 1 chr15 GO:0010817 Not Cancer Driver No 17 0.124 22 5 0.227 0
CRABP2_ENST00000368221 CRABP2 P29373 Cellular retinoic acid-binding protein 2 chr1 GO:0010817 Not Cancer Driver No 27 0.196 23 6 0.261 0
CRH CRH P06850 Corticoliberin chr8 GO:0010817 Not Cancer Driver No 10 0.051 131 9 0.069 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0010817 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRHR1 CRHR1 P34998 Corticotropin-releasing factor receptor 1 chr17 GO:0010817 Not Cancer Driver No 75 0.169 0 0 0.0 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0010817 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0010817 Not Cancer Driver No 72 0.121 100 12 0.12 0
CRYM CRYM Q14894 Ketimine reductase mu-crystallin chr16 GO:0010817 Not Cancer Driver No 34 0.108 10 0 0.0 1
CTSB CTSB P07858 Cathepsin B chr8 GO:0010817 Not Cancer Driver No 41 0.121 7 2 0.286 0
CTSG CTSG P08311 Cathepsin G chr14 GO:0010817 Not Cancer Driver No 65 0.255 80 29 0.362 0
CTSK CTSK P43235 Cathepsin K chr1 GO:0010817 Not Cancer Driver No 36 0.109 24 4 0.167 6
CTSL CTSL P07711 Procathepsin L chr9 GO:0010817 Not Cancer Driver No 47 0.141 34 4 0.118 0
CTSZ CTSZ Q9UBR2 Cathepsin Z chr20 GO:0010817 Not Cancer Driver No 30 0.099 10 0 0.0 0
CYP11A1 CYP11A1 P05108 Cholesterol side-chain cleavage enzyme, mitochondrial chr15 GO:0010817 Not Cancer Driver No 92 0.177 27 6 0.222 6
CYP11B1 CYP11B1 P15538 Cytochrome P450 11B1, mitochondrial chr8 GO:0010817 Not Cancer Driver No 177 0.352 7 1 0.143 50
CYP11B2 CYP11B2 P19099 Cytochrome P450 11B2, mitochondrial chr8 GO:0010817 Not Cancer Driver No 148 0.294 6 0 0.0 6
CYP17A1 CYP17A1 P05093 Steroid 17-alpha-hydroxylase/17,20 lyase chr10 GO:0010817 Not Cancer Driver No 64 0.126 34 2 0.059 26
CYP19A1_ENST00000396404 CYP19A1 P11511 Aromatase chr15 GO:0010817 Not Cancer Driver No 91 0.181 2 1 0.5 5
CYP1A1 CYP1A1 P04798 Cytochrome P450 1A1 chr15 GO:0010817 Not Cancer Driver No 81 0.158 17 2 0.118 0
CYP1A2 CYP1A2 P05177 Cytochrome P450 1A2 chr15 GO:0010817 Not Cancer Driver No 93 0.18 23 3 0.13 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0010817 Not Cancer Driver No 61 0.112 31 3 0.097 40
CYP21A2_ENST00000643666 CYP21A2 P08686 Steroid 21-hydroxylase chr6 GO:0010817 Not Cancer Driver No 70 0.142 49 16 0.327 66
CYP26A1 CYP26A1 O43174 Cytochrome P450 26A1 chr10 GO:0010817 Not Cancer Driver No 84 0.169 9 1 0.111 0
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0010817 Not Cancer Driver No 113 0.221 10 3 0.3 2
CYP26C1 CYP26C1 Q6V0L0 Cytochrome P450 26C1 chr10 GO:0010817 Not Cancer Driver No 32 0.061 56 6 0.107 0
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0010817 Not Cancer Driver No 71 0.14 79 13 0.165 18
CYP2C18 CYP2C18 P33260 Cytochrome P450 2C18 chr10 GO:0010817 Not Cancer Driver No 114 0.233 11 1 0.091 0
CYP2C8 CYP2C8 P10632 Cytochrome P450 2C8 chr10 GO:0010817 Census, Compendium Yes 113 0.231 30 11 0.367 0
CYP2C9 CYP2C9 P11712 Cytochrome P450 2C9 chr10 GO:0010817 Not Cancer Driver No 122 0.249 36 14 0.389 0
CYP2D6_ENST00000645361 CYP2D6 P10635 Cytochrome P450 2D6 chr22 GO:0010817 Not Cancer Driver No 76 0.153 66 8 0.121 0
CYP2S1 CYP2S1 Q96SQ9 Cytochrome P450 2S1 chr19 GO:0010817 Not Cancer Driver No 75 0.149 46 10 0.217 0
CYP2W1 CYP2W1 Q8TAV3 Cytochrome P450 2W1 chr7 GO:0010817 Not Cancer Driver No 51 0.104 55 6 0.109 0
CYP3A4 CYP3A4 P08684 Cytochrome P450 3A4 chr7 GO:0010817 Not Cancer Driver No 91 0.181 22 2 0.091 1
CYP3A5 CYP3A5 P20815 Cytochrome P450 3A5 chr7 GO:0010817 Not Cancer Driver No 67 0.133 38 5 0.132 0
CYP3A7 CYP3A7 P24462 Cytochrome P450 3A7 chr7 GO:0010817 Not Cancer Driver No 91 0.181 17 6 0.353 0
CYP46A1 CYP46A1 Q9Y6A2 Cholesterol 24-hydroxylase chr14 GO:0010817 Not Cancer Driver No 92 0.184 23 4 0.174 0
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0010817 Not Cancer Driver No 144 0.187 680 125 0.184 0
DGAT1 DGAT1 O75907 Diacylglycerol O-acyltransferase 1 chr8 GO:0010817 Not Cancer Driver No 52 0.107 62 0 0.0 0
DGAT2 DGAT2 Q96PD7 Diacylglycerol O-acyltransferase 2 chr11 GO:0010817 Not Cancer Driver No 56 0.144 17 2 0.118 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0010817 Not Cancer Driver No 56 0.059 264 11 0.042 0
DHCR7 DHCR7 Q9UBM7 7-dehydrocholesterol reductase chr11 GO:0010817 Not Cancer Driver No 85 0.179 7 1 0.143 53
DHRS13 DHRS13 Q6UX07 Dehydrogenase/reductase SDR family member 13 chr17 GO:0010817 Not Cancer Driver No 26 0.069 101 8 0.079 0
DHRS2_ENST00000250383 DHRS2 Q13268 Dehydrogenase/reductase SDR family member 2, mitochondrial chr14 GO:0010817 Not Cancer Driver No 47 0.168 0 0 0.0 0
DHRS3 DHRS3 O75911 Short-chain dehydrogenase/reductase 3 chr1 GO:0010817 Not Cancer Driver No 33 0.109 0 0 0.0 0
DHRS4 DHRS4 Q9BTZ2 Dehydrogenase/reductase SDR family member 4 chr14 GO:0010817 Not Cancer Driver No 30 0.108 38 4 0.105 0
DHRS7_ENST00000557185 DHRS7 Q9Y394 Dehydrogenase/reductase SDR family member 7 chr14 GO:0010817 Not Cancer Driver No 37 0.109 10 0 0.0 0
DHRS9_ENST00000602501 DHRS9 Q9BPW9 Dehydrogenase/reductase SDR family member 9 chr2 GO:0010817 Not Cancer Driver No 67 0.21 3 0 0.0 0
DIO1_ENST00000613679 DIO1 P49895 Type I iodothyronine deiodinase chr1 GO:0010817 Not Cancer Driver No 28 0.112 0 0 0.0 0
DIO2_ENST00000557010 DIO2 Q92813 Type II iodothyronine deiodinase chr14 GO:0010817 Not Cancer Driver No 73 0.267 44 4 0.091 0
DIO3 DIO3 P55073 Thyroxine 5-deiodinase chr14 GO:0010817 Not Cancer Driver No 88 0.289 71 18 0.254 0
DISP1 DISP1 Q96F81 Protein dispatched homolog 1 chr1 GO:0010817 Not Cancer Driver No 212 0.139 252 35 0.139 0
DKK3_ENST00000326932 DKK3 Q9UBP4 Dickkopf-related protein 3 chr11 GO:0010817 Not Cancer Driver No 44 0.126 161 22 0.137 0
DOC2B DOC2B Q14184 Double C2-like domain-containing protein beta chr17 GO:0010817 Not Cancer Driver No 10 0.024 197 3 0.015 0
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0010817 Not Cancer Driver No 151 0.197 8 1 0.125 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0010817 Not Cancer Driver No 127 0.287 124 45 0.363 0
DUOX1 DUOX1 Q9NRD9 Dual oxidase 1 chr15 GO:0010817 Not Cancer Driver No 193 0.124 158 17 0.108 0
DUOX2 DUOX2 Q9NRD8 Dual oxidase 2 chr15 GO:0010817 Not Cancer Driver No 245 0.158 182 25 0.137 3
DUOXA1_ENST00000560572 DUOXA1 Q1HG43 Dual oxidase maturation factor 1 chr15 GO:0010817 Not Cancer Driver No 40 0.117 38 7 0.184 0
DUOXA2 DUOXA2 Q1HG44 Dual oxidase maturation factor 2 chr15 GO:0010817 Not Cancer Driver No 40 0.125 0 0 0.0 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 GO:0010817 Not Cancer Driver No 118 0.153 99 26 0.263 1
ECE2 ECE2 P0DPD6 Endothelin-converting enzyme 2 chr3 GO:0010817 Not Cancer Driver No 178 0.219 149 40 0.268 0
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0010817 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0010817 Not Cancer Driver No 112 0.253 56 19 0.339 6
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0010817 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0010817 Not Cancer Driver No 78 0.144 501 72 0.144 0
ENPEP ENPEP Q07075 Glutamyl aminopeptidase chr4 GO:0010817 Compendium Yes 235 0.246 130 44 0.338 0
EPHA5_ENST00000273854 EPHA5 P54756 Ephrin type-A receptor 5 chr4 GO:0010817 Not Cancer Driver No 341 0.329 83 39 0.47 0
ERO1A ERO1A Q96HE7 ERO1-like protein alpha chr14 GO:0010817 Not Cancer Driver No 48 0.103 32 5 0.156 0
ESR1_ENST00000206249 ESR1 P03372 Estrogen receptor chr6 GO:0010817 Census, Compendium Yes 121 0.203 195 27 0.138 2
FAM129B NIBAN2 Q96TA1 Protein Niban 2 chr9 GO:0010817 Not Cancer Driver No 99 0.133 206 20 0.097 0
FAM3D FAM3D Q96BQ1 Protein FAM3D chr3 GO:0010817 Not Cancer Driver No 43 0.192 16 4 0.25 0
FFAR1 FFAR1 O14842 Free fatty acid receptor 1 chr19 GO:0010817 Not Cancer Driver No 45 0.15 2 0 0.0 0
FFAR3 FFAR3 O14843 Free fatty acid receptor 3 chr19 GO:0010817 Not Cancer Driver No 78 0.225 29 6 0.207 0
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0010817 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0010817 Not Cancer Driver No 84 0.335 97 51 0.526 7
FKBP1B FKBP1B P68106 Peptidyl-prolyl cis-trans isomerase FKBP1B chr2 GO:0010817 Not Cancer Driver No 10 0.093 58 4 0.069 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0010817 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0010817 Compendium Yes 70 0.153 258 34 0.132 0
FOXD1 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0010817 Not Cancer Driver No 10 0.022 259 5 0.019 0
FOXE1 FOXE1 O00358 Forkhead box protein E1 chr9 GO:0010817 Not Cancer Driver No 38 0.102 133 5 0.038 4
FOXL2 FOXL2 P58012 Forkhead box protein L2 chr3 GO:0010817 Census, Compendium Yes 39 0.104 257 20 0.078 26
FSHB_ENST00000254122 FSHB P01225 Follitropin subunit beta chr11 GO:0010817 Not Cancer Driver No 31 0.24 0 0 0.0 1
FURIN_ENST00000610579 FURIN P09958 Furin chr15 GO:0010817 Not Cancer Driver No 93 0.117 283 35 0.124 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0010817 Not Cancer Driver No 57 0.106 33 5 0.152 19
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0010817 Not Cancer Driver No 150 0.156 142 17 0.12 0
GAL GAL P22466 Galanin peptides chr11 GO:0010817 Not Cancer Driver No 17 0.138 36 2 0.056 1
GALR1 GALR1 P47211 Galanin receptor type 1 chr18 GO:0010817 Not Cancer Driver No 68 0.195 32 2 0.062 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0010817 Census, Compendium Yes 111 0.251 364 87 0.239 2
GCG GCG P01275 Pro-glucagon chr2 GO:0010817 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCK_ENST00000403799 GCK P35557 Hexokinase-4 chr7 GO:0010817 Not Cancer Driver No 88 0.189 73 14 0.192 107
GCNT4 GCNT4 Q9P109 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 chr5 GO:0010817 Not Cancer Driver No 64 0.141 0 0 0.0 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0010817 Not Cancer Driver No 72 0.159 53 15 0.283 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:0010817 Not Cancer Driver No 57 0.135 199 29 0.146 2
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0010817 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0010817 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0010817 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHR_ENST00000612382 GHR P10912 Growth hormone receptor chr5 GO:0010817 Not Cancer Driver No 173 0.271 229 66 0.288 19
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0010817 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0010817 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0010817 Not Cancer Driver No 45 0.097 41 0 0.0 0
GJA1 GJA1 P17302 Gap junction alpha-1 protein chr6 GO:0010817 Not Cancer Driver No 86 0.225 110 26 0.236 50
GLUD1 GLUD1 P00367 Glutamate dehydrogenase 1, mitochondrial chr10 GO:0010817 Not Cancer Driver No 50 0.09 107 14 0.131 13
GLUL_ENST00000331872 GLUL P15104 Glutamine synthetase chr1 GO:0010817 Not Cancer Driver No 66 0.177 104 21 0.202 2
GNB3 GNB3 P16520 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 chr12 GO:0010817 Not Cancer Driver No 51 0.15 13 1 0.077 0
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0010817 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPLD1 GPLD1 P80108 Phosphatidylinositol-glycan-specific phospholipase D chr6 GO:0010817 Not Cancer Driver No 153 0.182 36 9 0.25 0
GPR27 GPR27 Q9NS67 Probable G-protein coupled receptor 27 chr3 GO:0010817 Not Cancer Driver No 26 0.069 23 1 0.043 0
GPR68_ENST00000535815 GPR68 Q15743 Ovarian cancer G-protein coupled receptor 1 chr14 GO:0010817 Not Cancer Driver No 42 0.115 45 1 0.022 1
H6PD_ENST00000377403 H6PD O95479 GDH/6PGL endoplasmic bifunctional protein chr1 GO:0010817 Not Cancer Driver No 96 0.121 39 3 0.077 2
HADH_ENST00000309522 HADH Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial chr4 GO:0010817 Not Cancer Driver No 33 0.105 22 5 0.227 3
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0010817 Not Cancer Driver No 78 0.215 43 8 0.186 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0010817 Census Yes 118 0.143 435 51 0.117 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0010817 Not Cancer Driver No 48 0.18 12 1 0.083 0
HMGN3_ENST00000344726 HMGN3 Q15651 High mobility group nucleosome-binding domain-containing protein 3 chr6 GO:0010817 Not Cancer Driver No 14 0.141 99 14 0.141 0
HPN_ENST00000392226 HPN P05981 Serine protease hepsin chr19 GO:0010817 Not Cancer Driver No 60 0.144 12 0 0.0 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX GO:0010817 Not Cancer Driver No 27 0.103 15 3 0.2 11
HSD17B11 HSD17B11 Q8NBQ5 Estradiol 17-beta-dehydrogenase 11 chr4 GO:0010817 Not Cancer Driver No 28 0.093 3 0 0.0 0
HSD17B12 HSD17B12 Q53GQ0 Very-long-chain 3-oxoacyl-CoA reductase chr11 GO:0010817 Not Cancer Driver No 32 0.103 9 0 0.0 0
HSD17B1_ENST00000585807 HSD17B1 P14061 17-beta-hydroxysteroid dehydrogenase type 1 chr17 GO:0010817 Not Cancer Driver No 48 0.146 59 28 0.475 0
HSD17B2 HSD17B2 P37059 17-beta-hydroxysteroid dehydrogenase type 2 chr16 GO:0010817 Not Cancer Driver No 55 0.142 6 1 0.167 0
HSD17B3 HSD17B3 P37058 17-beta-hydroxysteroid dehydrogenase type 3 chr9 GO:0010817 Not Cancer Driver No 42 0.135 0 0 0.0 15
HSD17B4_ENST00000256216 HSD17B4 P51659 Peroxisomal multifunctional enzyme type 2 chr5 GO:0010817 Not Cancer Driver No 99 0.135 82 12 0.146 4
HSD17B6_ENST00000322165 HSD17B6 O14756 17-beta-hydroxysteroid dehydrogenase type 6 chr12 GO:0010817 Not Cancer Driver No 35 0.11 5 1 0.2 0
HSD17B7 HSD17B7 P56937 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 chr1 GO:0010817 Not Cancer Driver No 33 0.097 0 0 0.0 0
HSD17B8 HSD17B8 Q92506 (3R)-3-hydroxyacyl-CoA dehydrogenase chr6 GO:0010817 Not Cancer Driver No 20 0.077 26 1 0.038 0
HSD3B1 HSD3B1 P14060 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 chr1 GO:0010817 Not Cancer Driver No 69 0.185 25 3 0.12 0
HSD3B2_ENST00000369416 HSD3B2 P26439 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 chr1 GO:0010817 Not Cancer Driver No 83 0.223 24 9 0.375 28
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0010817 Not Cancer Driver No 140 0.306 40 11 0.275 0
IDE IDE P14735 Insulin-degrading enzyme chr10 GO:0010817 Not Cancer Driver No 90 0.088 96 8 0.083 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0010817 Not Cancer Driver No 183 0.134 265 37 0.14 6
IL11 IL11 P20809 Interleukin-11 chr19 GO:0010817 Not Cancer Driver No 19 0.095 69 8 0.116 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0010817 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL4I1_ENST00000391826 IL4I1 Q96RQ9 L-amino-acid oxidase chr19 GO:0010817 Not Cancer Driver No 65 0.115 136 14 0.103 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0010817 Not Cancer Driver No 35 0.165 58 7 0.121 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0010817 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0010817 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0010817 Not Cancer Driver No 61 0.15 98 5 0.051 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0010817 Not Cancer Driver No 161 0.13 1072 133 0.124 2
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0010817 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0010817 Not Cancer Driver No 85 0.244 180 41 0.228 0
IYD_ENST00000344419 IYD Q6PHW0 Iodotyrosine deiodinase 1 chr6 GO:0010817 Not Cancer Driver No 53 0.183 75 21 0.28 2
JAGN1 JAGN1 Q8N5M9 Protein jagunal homolog 1 chr3 GO:0010817 Not Cancer Driver No 21 0.115 12 2 0.167 5
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0010817 Census, Compendium Yes 136 0.12 59 5 0.085 5
KCNB1_ENST00000635465 KCNB1 Q14721 Potassium voltage-gated channel subfamily B member 1 chr20 GO:0010817 Not Cancer Driver No 192 0.224 417 100 0.24 6
KCNJ11 KCNJ11 Q14654 ATP-sensitive inward rectifier potassium channel 11 chr11 GO:0010817 Not Cancer Driver No 48 0.123 19 3 0.158 46
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0010817 Not Cancer Driver No 78 0.115 219 20 0.091 132
KDM5B_ENST00000367265 KDM5B Q9UGL1 Lysine-specific demethylase 5B chr1 GO:0010817 Not Cancer Driver No 219 0.142 388 58 0.149 0
KISS1 KISS1 Q15726 Metastasis-suppressor KiSS-1 chr1 GO:0010817 Not Cancer Driver No 17 0.123 116 14 0.121 1
KLF7 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0010817 Not Cancer Driver No 46 0.152 72 7 0.097 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0010817 Not Cancer Driver No 62 0.254 28 12 0.429 0
LEP LEP P41159 Leptin chr7 GO:0010817 Not Cancer Driver No 29 0.174 0 0 0.0 2
LHB LHB P01229 Lutropin subunit beta chr19 GO:0010817 Not Cancer Driver No 20 0.142 0 0 0.0 1
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0010817 Not Cancer Driver No 25 0.124 0 0 0.0 0
LIPE LIPE Q05469 Hormone-sensitive lipase chr19 GO:0010817 Not Cancer Driver No 123 0.114 496 65 0.131 0
LRAT LRAT O95237 Lecithin retinol acyltransferase chr4 GO:0010817 Not Cancer Driver No 54 0.235 2 0 0.0 1
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0010817 Not Cancer Driver No 253 0.157 188 28 0.149 55
LRP5L_ENST00000402785 LRP5L A4QPB2 Low-density lipoprotein receptor-related protein 5-like protein chr22 GO:0010817 Not Cancer Driver No 38 0.151 39 5 0.128 0
LRRC8A_ENST00000372599 LRRC8A Q8IWT6 Volume-regulated anion channel subunit LRRC8A chr9 GO:0010817 Not Cancer Driver No 105 0.13 32 3 0.094 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0010817 Census Yes 95 0.186 84 12 0.143 0
MBOAT4 MBOAT4 Q96T53 Ghrelin O-acyltransferase chr8 GO:0010817 Not Cancer Driver No 23 0.053 0 0 0.0 0
MCU MCU Q8NE86 Calcium uniporter protein, mitochondrial chr10 GO:0010817 Not Cancer Driver No 41 0.117 13 0 0.0 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0010817 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MIDN MIDN Q504T8 Midnolin chr19 GO:0010817 Not Cancer Driver No 43 0.092 446 43 0.096 0
MPC2 MPC2 O95563 Mitochondrial pyruvate carrier 2 chr1 GO:0010817 Not Cancer Driver No 13 0.102 0 0 0.0 0
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0010817 Not Cancer Driver No 104 0.287 8 1 0.125 0
MYRIP MYRIP Q8NFW9 Rab effector MyRIP chr3 GO:0010817 Not Cancer Driver No 133 0.155 599 95 0.159 0
NDUFAF2 NDUFAF2 Q8N183 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 chr5 GO:0010817 Not Cancer Driver No 21 0.124 116 13 0.112 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0010817 Not Cancer Driver No 104 0.107 344 38 0.11 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0010817 Not Cancer Driver No 35 0.15 171 16 0.094 0
NKX6-1 NKX6-1 P78426 Homeobox protein Nkx-6.1 chr4 GO:0010817 Not Cancer Driver No 38 0.104 325 34 0.105 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0010817 Not Cancer Driver No 91 0.109 300 19 0.063 0
NMB_ENST00000360476 NMB P08949 Neuromedin-B chr15 GO:0010817 Not Cancer Driver No 6 0.05 30 2 0.067 0
NNAT NNAT Q16517 Neuronatin chr20 GO:0010817 Not Cancer Driver No 9 0.111 8 0 0.0 0
NPVF NPVF Q9HCQ7 Pro-FMRFamide-related neuropeptide VF chr7 GO:0010817 Not Cancer Driver No 33 0.168 106 17 0.16 0
NR0B2 NR0B2 Q15466 Nuclear receptor subfamily 0 group B member 2 chr1 GO:0010817 Not Cancer Driver No 35 0.136 10 2 0.2 0
NR1D1 NR1D1 P20393 Nuclear receptor subfamily 1 group D member 1 chr17 GO:0010817 Not Cancer Driver No 81 0.132 348 49 0.141 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0010817 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR5A1 NR5A1 Q13285 Steroidogenic factor 1 chr9 GO:0010817 Not Cancer Driver No 60 0.13 133 29 0.218 24
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0010817 Not Cancer Driver No 117 0.308 18 5 0.278 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0010817 Not Cancer Driver No 83 0.103 386 39 0.101 0
OSM OSM P13725 Oncostatin-M chr22 GO:0010817 Not Cancer Driver No 43 0.171 114 24 0.211 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 GO:0010817 Not Cancer Driver No 80 0.154 39 5 0.128 11
PAPSS2_ENST00000361175 PAPSS2 O95340 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 chr10 GO:0010817 Not Cancer Driver No 81 0.132 100 7 0.07 4
PASK_ENST00000234040 PASK Q96RG2 PAS domain-containing serine/threonine-protein kinase chr2 GO:0010817 Not Cancer Driver No 181 0.137 412 62 0.15 0
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0010817 Census Yes 84 0.187 291 55 0.189 4
PCK2 PCK2 Q16822 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial chr14 GO:0010817 Not Cancer Driver No 91 0.142 139 13 0.094 0
PCSK1 PCSK1 P29120 Neuroendocrine convertase 1 chr5 GO:0010817 Not Cancer Driver No 139 0.185 336 61 0.182 2
PCSK1N PCSK1N Q9UHG2 ProSAAS chrX GO:0010817 Not Cancer Driver No 7 0.027 187 7 0.037 0
PCSK2 PCSK2 P16519 Neuroendocrine convertase 2 chr20 GO:0010817 Not Cancer Driver No 144 0.226 153 39 0.255 0
PCSK4 PCSK4 Q6UW60 Proprotein convertase subtilisin/kexin type 4 chr19 GO:0010817 Not Cancer Driver No 83 0.11 149 20 0.134 0
PCSK5 PCSK5 Q92824 Proprotein convertase subtilisin/kexin type 5 chr9 GO:0010817 Not Cancer Driver No 319 0.172 168 25 0.149 0
PCSK6 PCSK6 P29122 Proprotein convertase subtilisin/kexin type 6 chr15 GO:0010817 Not Cancer Driver No 138 0.142 207 45 0.217 0
PCSK7 PCSK7 Q16549 Proprotein convertase subtilisin/kexin type 7 chr11 GO:0010817 Not Cancer Driver No 101 0.129 262 31 0.118 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0010817 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0010817 Not Cancer Driver No 32 0.113 238 23 0.097 0
PFKFB2 PFKFB2 O60825 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 chr1 GO:0010817 Not Cancer Driver No 68 0.135 97 18 0.186 0
PFKL PFKL P17858 ATP-dependent 6-phosphofructokinase, liver type chr21 GO:0010817 Not Cancer Driver No 91 0.117 29 4 0.138 0
PFKM_ENST00000550924 PFKM P08237 ATP-dependent 6-phosphofructokinase, muscle type chr12 GO:0010817 Not Cancer Driver No 80 0.103 70 8 0.114 9
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 GO:0010817 Not Cancer Driver No 24 0.074 9 0 0.0 0
PLA2G3 PLA2G3 Q9NZ20 Group 3 secretory phospholipase A2 chr22 GO:0010817 Not Cancer Driver No 115 0.226 175 39 0.223 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0010817 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2G7 PLA2G7 Q13093 Platelet-activating factor acetylhydrolase chr6 GO:0010817 Not Cancer Driver No 70 0.159 27 7 0.259 2
PLB1 PLB1 Q6P1J6 Phospholipase B1, membrane-associated chr2 GO:0010817 Not Cancer Driver No 223 0.153 399 57 0.143 0
PLEKHA1 PLEKHA1 Q9HB21 Pleckstrin homology domain-containing family A member 1 chr10 GO:0010817 Not Cancer Driver No 61 0.151 191 32 0.168 0
PNLIP PNLIP P16233 Pancreatic triacylglycerol lipase chr10 GO:0010817 Not Cancer Driver No 124 0.267 32 11 0.344 1
PNPLA2 PNPLA2 Q96AD5 Patatin-like phospholipase domain-containing protein 2 chr11 GO:0010817 Not Cancer Driver No 35 0.069 101 4 0.04 1
PNPLA4_ENST00000444736 PNPLA4 P41247 Patatin-like phospholipase domain-containing protein 4 chrX GO:0010817 Not Cancer Driver No 41 0.162 3 0 0.0 0
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0010817 Not Cancer Driver No 50 0.187 198 38 0.192 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0010817 Not Cancer Driver No 62 0.092 93 4 0.043 9
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0010817 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0010817 Census Yes 72 0.143 44 4 0.091 3
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0010817 Compendium Yes 85 0.163 140 27 0.193 7
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0010817 Not Cancer Driver No 67 0.128 139 18 0.129 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0010817 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0010817 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRLHR_ENST00000636925 PRLHR P49683 Prolactin-releasing peptide receptor chr10 GO:0010817 Not Cancer Driver No 72 0.195 17 2 0.118 0
PRMT3 PRMT3 O60678 Protein arginine N-methyltransferase 3 chr11 GO:0010817 Not Cancer Driver No 68 0.128 52 9 0.173 0
PSMD9 PSMD9 O00233 26S proteasome non-ATPase regulatory subunit 9 chr12 GO:0010817 Not Cancer Driver No 22 0.099 173 16 0.092 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0010817 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPRN PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 GO:0010817 Not Cancer Driver No 142 0.145 498 73 0.147 0
PTPRN2 PTPRN2 Q92932 Receptor-type tyrosine-protein phosphatase N2 chr7 GO:0010817 Not Cancer Driver No 274 0.27 580 169 0.291 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0010817 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB11FIP1 RAB11FIP1 Q6WKZ4 Rab11 family-interacting protein 1 chr8 GO:0010817 Not Cancer Driver No 145 0.113 1118 133 0.119 0
RAB11FIP2_ENST00000355624 RAB11FIP2 Q7L804 Rab11 family-interacting protein 2 chr10 GO:0010817 Not Cancer Driver No 66 0.129 356 43 0.121 0
RAB11FIP3 RAB11FIP3 O75154 Rab11 family-interacting protein 3 chr16 GO:0010817 Not Cancer Driver No 51 0.067 605 33 0.055 0
RAB11FIP5 RAB11FIP5 Q9BXF6 Rab11 family-interacting protein 5 chr2 GO:0010817 Not Cancer Driver No 83 0.127 533 70 0.131 0
RAB1A RAB1A P62820 Ras-related protein Rab-1A chr2 GO:0010817 Not Cancer Driver No 16 0.078 38 2 0.053 0
RAB8B RAB8B Q92930 Ras-related protein Rab-8B chr15 GO:0010817 Not Cancer Driver No 22 0.106 29 2 0.069 0
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0010817 Census, Compendium Yes 89 0.137 169 38 0.225 22
RBP1_ENST00000619087 RBP1 P09455 Retinol-binding protein 1 chr3 GO:0010817 Not Cancer Driver No 24 0.178 0 0 0.0 0
RBP4 RBP4 P02753 Retinol-binding protein 4 chr10 GO:0010817 Not Cancer Driver No 30 0.149 8 1 0.125 4
RDH10 RDH10 Q8IZV5 Retinol dehydrogenase 10 chr8 GO:0010817 Not Cancer Driver No 33 0.097 8 0 0.0 0
RDH11 RDH11 Q8TC12 Retinol dehydrogenase 11 chr14 GO:0010817 Not Cancer Driver No 25 0.079 2 0 0.0 0
RDH12_ENST00000267502 RDH12 Q96NR8 Retinol dehydrogenase 12 chr14 GO:0010817 Not Cancer Driver No 41 0.13 0 0 0.0 10
RDH13 RDH13 Q8NBN7 Retinol dehydrogenase 13 chr19 GO:0010817 Not Cancer Driver No 42 0.127 48 7 0.146 0
RDH14 RDH14 Q9HBH5 Retinol dehydrogenase 14 chr2 GO:0010817 Not Cancer Driver No 22 0.065 21 0 0.0 0
RDH16 RDH16 O75452 Retinol dehydrogenase 16 chr12 GO:0010817 Not Cancer Driver No 46 0.145 0 0 0.0 0
RDH5_ENST00000548082 RDH5 Q92781 Retinol dehydrogenase 5 chr12 GO:0010817 Not Cancer Driver No 39 0.123 0 0 0.0 18
REN REN P00797 Renin chr1 GO:0010817 Not Cancer Driver No 60 0.148 10 0 0.0 3
REST REST Q13127 RE1-silencing transcription factor chr4 GO:0010817 Not Cancer Driver No 142 0.129 868 113 0.13 4
RETN RETN Q9HD89 Resistin chr19 GO:0010817 Not Cancer Driver No 10 0.093 0 0 0.0 0
RETSAT RETSAT Q6NUM9 All-trans-retinol 13,14-reductase chr2 GO:0010817 Not Cancer Driver No 98 0.161 25 5 0.2 0
RFX6 RFX6 Q8HWS3 DNA-binding protein RFX6 chr6 GO:0010817 Not Cancer Driver No 239 0.258 422 94 0.223 3
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 GO:0010817 Not Cancer Driver No 109 0.205 10 1 0.1 44
RPH3AL RPH3AL Q9UNE2 Rab effector Noc2 chr17 GO:0010817 Not Cancer Driver No 40 0.127 162 20 0.123 0
SCG5 SCG5 P05408 Neuroendocrine protein 7B2 chr15 GO:0010817 Not Cancer Driver No 25 0.118 174 21 0.121 0
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0010817 Not Cancer Driver No 90 0.141 62 4 0.065 13
SCPEP1 SCPEP1 Q9HB40 Retinoid-inducible serine carboxypeptidase chr17 GO:0010817 Not Cancer Driver No 46 0.102 1 0 0.0 0
SCT SCT P09683 Secretin chr11 GO:0010817 Not Cancer Driver No 4 0.033 71 3 0.042 0
SDR16C5_ENST00000303749 SDR16C5 Q8N3Y7 Epidermal retinol dehydrogenase 2 chr8 GO:0010817 Not Cancer Driver No 81 0.262 4 0 0.0 0
SELENOM_ENST00000611680 SELENOM Q8WWX9 Selenoprotein M chr22 GO:0010817 Not Cancer Driver No 10 0.069 21 2 0.095 0
SELENOT SELENOT P62341 Thioredoxin reductase-like selenoprotein T chr3 GO:0010817 Not Cancer Driver No 25 0.128 0 0 0.0 0
SERP1_ENST00000239944 SERP1 Q9Y6X1 Stress-associated endoplasmic reticulum protein 1 chr3 GO:0010817 Not Cancer Driver No 6 0.091 30 2 0.067 0
SERPINA7 SERPINA7 P05543 Thyroxine-binding globulin chrX GO:0010817 Not Cancer Driver No 108 0.26 11 2 0.182 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0010817 Not Cancer Driver No 40 0.127 39 7 0.179 0
SGPL1 SGPL1 O95470 Sphingosine-1-phosphate lyase 1 chr10 GO:0010817 Not Cancer Driver No 68 0.12 19 3 0.158 2
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0010817 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIDT2_ENST00000620360 SIDT2 Q8NBJ9 SID1 transmembrane family member 2 chr11 GO:0010817 Not Cancer Driver No 113 0.136 23 6 0.261 0
SIN3A_ENST00000360439 SIN3A Q96ST3 Paired amphipathic helix protein Sin3a chr15 GO:0010817 Compendium Yes 172 0.135 617 73 0.118 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0010817 Not Cancer Driver No 46 0.146 4 0 0.0 0
SLC16A10 SLC16A10 Q8TF71 Monocarboxylate transporter 10 chr6 GO:0010817 Not Cancer Driver No 57 0.111 82 2 0.024 0
SLC16A2 SLC16A2 P36021 Monocarboxylate transporter 8 chrX GO:0010817 Not Cancer Driver No 84 0.156 124 12 0.097 20
SLC30A5 SLC30A5 Q8TAD4 Zinc transporter 5 chr5 GO:0010817 Not Cancer Driver No 58 0.076 33 0 0.0 0
SLC30A6_ENST00000282587 SLC30A6 Q6NXT4 Zinc transporter 6 chr2 GO:0010817 Not Cancer Driver No 54 0.117 93 7 0.075 0
SLC30A8 SLC30A8 Q8IWU4 Zinc transporter 8 chr8 GO:0010817 Not Cancer Driver No 115 0.312 25 9 0.36 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 GO:0010817 Not Cancer Driver No 34 0.069 42 3 0.071 4
SLC5A5 SLC5A5 Q92911 Sodium/iodide cotransporter chr19 GO:0010817 Not Cancer Driver No 96 0.149 59 7 0.119 5
SLC7A5 SLC7A5 Q01650 Large neutral amino acids transporter small subunit 1 chr16 GO:0010817 Not Cancer Driver No 62 0.122 35 1 0.029 0
SLC7A8 SLC7A8 Q9UHI5 Large neutral amino acids transporter small subunit 2 chr14 GO:0010817 Not Cancer Driver No 70 0.131 63 11 0.175 0
SLC9B2 SLC9B2 Q86UD5 Sodium/hydrogen exchanger 9B2 chr4 GO:0010817 Not Cancer Driver No 68 0.127 80 16 0.2 0
SLCO1B1 SLCO1B1 Q9Y6L6 Solute carrier organic anion transporter family member 1B1 chr12 GO:0010817 Not Cancer Driver No 177 0.256 33 3 0.091 0
SLCO1C1_ENST00000266509 SLCO1C1 Q9NYB5 Solute carrier organic anion transporter family member 1C1 chr12 GO:0010817 Not Cancer Driver No 197 0.277 19 7 0.368 0
SLCO4A1 SLCO4A1 Q96BD0 Solute carrier organic anion transporter family member 4A1 chr20 GO:0010817 Not Cancer Driver No 106 0.147 66 5 0.076 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0010817 Census, Compendium Yes 198 0.359 195 17 0.087 8
SNAP23 SNAP23 O00161 Synaptosomal-associated protein 23 chr15 GO:0010817 Not Cancer Driver No 18 0.085 179 16 0.089 0
SNX4 SNX4 O95219 Sorting nexin-4 chr3 GO:0010817 Not Cancer Driver No 31 0.069 101 5 0.05 0
SNX6 SNX6 Q9UNH7 Sorting nexin-6 chr14 GO:0010817 Not Cancer Driver No 33 0.081 85 7 0.082 0
SOX4 SOX4 Q06945 Transcription factor SOX-4 chr6 GO:0010817 Not Cancer Driver No 28 0.059 400 24 0.06 4
SOX8 SOX8 P57073 Transcription factor SOX-8 chr16 GO:0010817 Not Cancer Driver No 43 0.096 403 39 0.097 0
SPP1 SPP1 P10451 Osteopontin chr4 GO:0010817 Not Cancer Driver No 56 0.178 296 54 0.182 0
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0010817 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRD5A2 SRD5A2 P31213 3-oxo-5-alpha-steroid 4-dehydrogenase 2 chr2 GO:0010817 Not Cancer Driver No 48 0.189 0 0 0.0 21
SRD5A3 SRD5A3 Q9H8P0 Polyprenol reductase chr4 GO:0010817 Not Cancer Driver No 35 0.11 0 0 0.0 0
SREBF1_ENST00000261646 SREBF1 P36956 Sterol regulatory element-binding protein 1 chr17 GO:0010817 Not Cancer Driver No 127 0.111 528 64 0.121 4
SRI SRI P30626 Sorcin chr7 GO:0010817 Not Cancer Driver No 15 0.076 32 2 0.062 0
STARD3 STARD3 Q14849 StAR-related lipid transfer protein 3 chr17 GO:0010817 Not Cancer Driver No 51 0.115 34 6 0.176 0
STAT5B STAT5B P51692 Signal transducer and activator of transcription 5B chr17 GO:0010817 Census, Compendium Yes 93 0.118 144 19 0.132 5
STC2 STC2 O76061 Stanniocalcin-2 chr5 GO:0010817 Not Cancer Driver No 71 0.235 112 29 0.259 0
STUB1 STUB1 Q9UNE7 E3 ubiquitin-protein ligase CHIP chr16 GO:0010817 Not Cancer Driver No 35 0.116 112 14 0.125 12
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0010817 Not Cancer Driver No 50 0.168 152 20 0.132 0
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 GO:0010817 Not Cancer Driver No 78 0.141 211 24 0.114 0
SULT1A1_ENST00000314752 SULT1A1 P50225 Sulfotransferase 1A1 chr16 GO:0010817 Not Cancer Driver No 69 0.234 14 3 0.214 0
SULT1B1 SULT1B1 O43704 Sulfotransferase 1B1 chr4 GO:0010817 Not Cancer Driver No 82 0.277 15 7 0.467 0
SULT1E1 SULT1E1 P49888 Sulfotransferase 1E1 chr4 GO:0010817 Not Cancer Driver No 76 0.259 15 5 0.333 0
SULT2A1 SULT2A1 Q06520 Sulfotransferase 2A1 chr19 GO:0010817 Not Cancer Driver No 50 0.175 0 0 0.0 0
SYT7_ENST00000263846 SYT7 O43581 Synaptotagmin-7 chr11 GO:0010817 Not Cancer Driver No 63 0.156 132 25 0.189 0
SYTL4 SYTL4 Q96C24 Synaptotagmin-like protein 4 chrX GO:0010817 Not Cancer Driver No 116 0.173 267 34 0.127 0
TACR2 TACR2 P21452 Substance-K receptor chr10 GO:0010817 Not Cancer Driver No 61 0.153 11 4 0.364 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0010817 Census, Compendium Yes 123 0.166 352 57 0.162 2
TCF7L2_ENST00000355995 TCF7L2 Q9NQB0 Transcription factor 7-like 2 chr10 GO:0010817 Census, Compendium Yes 122 0.197 516 93 0.18 0
TG TG P01266 Thyroglobulin chr8 GO:0010817 Not Cancer Driver No 620 0.224 276 73 0.264 7
TIPARP TIPARP Q7Z3E1 Protein mono-ADP-ribosyltransferase TIPARP chr3 GO:0010817 Not Cancer Driver No 65 0.099 200 20 0.1 0
TM7SF3 TM7SF3 Q9NS93 Transmembrane 7 superfamily member 3 chr12 GO:0010817 Not Cancer Driver No 83 0.146 18 4 0.222 0
TMF1 TMF1 P82094 TATA element modulatory factor chr3 GO:0010817 Not Cancer Driver No 109 0.1 946 99 0.105 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0010817 Not Cancer Driver No 52 0.164 56 1 0.018 1
TPO TPO P07202 Thyroid peroxidase chr2 GO:0010817 Not Cancer Driver No 326 0.349 163 69 0.423 24
TRH TRH P20396 Pro-thyrotropin-releasing hormone chr3 GO:0010817 Not Cancer Driver No 45 0.186 217 41 0.189 0
TRPM2_ENST00000397928 TRPM2 O94759 Transient receptor potential cation channel subfamily M member 2 chr21 GO:0010817 Not Cancer Driver No 286 0.19 266 44 0.165 0
TRPM4 TRPM4 Q8TD43 Transient receptor potential cation channel subfamily M member 4 chr19 GO:0010817 Not Cancer Driver No 152 0.125 149 18 0.121 12
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0010817 Not Cancer Driver No 142 0.163 231 34 0.147 44
TRPV6 TRPV6 Q9H1D0 Transient receptor potential cation channel subfamily V member 6 chr7 GO:0010817 Not Cancer Driver No 183 0.239 77 20 0.26 6
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0010817 Not Cancer Driver No 5 0.03 1 0 0.0 0
TTR TTR P02766 Transthyretin chr18 GO:0010817 Not Cancer Driver No 28 0.19 25 8 0.32 75
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 GO:0010817 Not Cancer Driver No 45 0.107 173 16 0.092 0
UCN UCN P55089 Urocortin chr2 GO:0010817 Not Cancer Driver No 7 0.056 61 4 0.066 0
UCN3 UCN3 Q969E3 Urocortin-3 chr10 GO:0010817 Not Cancer Driver No 22 0.137 74 11 0.149 0
UCP2 UCP2 P55851 Mitochondrial uncoupling protein 2 chr11 GO:0010817 Not Cancer Driver No 31 0.1 11 3 0.273 0
UGT1A1 UGT1A1 P22309 UDP-glucuronosyltransferase 1A1 chr2 GO:0010817 Not Cancer Driver No 100 0.188 11 2 0.182 55
UGT1A3 UGT1A3 P35503 UDP-glucuronosyltransferase 1A3 chr2 GO:0010817 Not Cancer Driver No 98 0.184 11 2 0.182 0
UGT1A7 UGT1A7 Q9HAW7 UDP-glucuronosyltransferase 1A7 chr2 GO:0010817 Not Cancer Driver No 110 0.208 11 2 0.182 0
UGT1A8 UGT1A8 Q9HAW9 UDP-glucuronosyltransferase 1A8 chr2 GO:0010817 Not Cancer Driver No 110 0.208 11 2 0.182 0
UGT1A9 UGT1A9 O60656 UDP-glucuronosyltransferase 1A9 chr2 GO:0010817 Not Cancer Driver No 121 0.228 11 2 0.182 0
UGT2B11 UGT2B11 O75310 UDP-glucuronosyltransferase 2B11 chr4 GO:0010817 Not Cancer Driver No 142 0.268 5 1 0.2 0
UGT2B15 UGT2B15 P54855 UDP-glucuronosyltransferase 2B15 chr4 GO:0010817 Not Cancer Driver No 140 0.264 12 4 0.333 0
UGT2B17 UGT2B17 O75795 UDP-glucuronosyltransferase 2B17 chr4 GO:0010817 Compendium Yes 112 0.211 12 1 0.083 0
UGT2B4 UGT2B4 P06133 UDP-glucuronosyltransferase 2B4 chr4 GO:0010817 Not Cancer Driver No 173 0.328 6 5 0.833 0
UGT2B7 UGT2B7 P16662 UDP-glucuronosyltransferase 2B7 chr4 GO:0010817 Not Cancer Driver No 124 0.234 6 0 0.0 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0010817 Not Cancer Driver No 7 0.06 47 4 0.085 3
VAMP3 VAMP3 Q15836 Vesicle-associated membrane protein 3 chr1 GO:0010817 Not Cancer Driver No 11 0.11 17 1 0.059 0
VAMP7_ENST00000286448 VAMP7 P51809 Vesicle-associated membrane protein 7 chrX GO:0010817 Not Cancer Driver No 38 0.173 4 1 0.25 0
VAMP8 VAMP8 Q9BV40 Vesicle-associated membrane protein 8 chr2 GO:0010817 Not Cancer Driver No 9 0.09 27 0 0.0 0
VIP VIP P01282 VIP peptides chr6 GO:0010817 Not Cancer Driver No 58 0.341 77 25 0.325 0
VSNL1_ENST00000404666 VSNL1 P62760 Visinin-like protein 1 chr2 GO:0010817 Not Cancer Driver No 28 0.147 15 3 0.2 0
WNT4 WNT4 P56705 Protein Wnt-4 chr1 GO:0010817 Not Cancer Driver No 30 0.085 39 4 0.103 4
YIPF5 YIPF5 Q969M3 Protein YIPF5 chr5 GO:0010817 Not Cancer Driver No 23 0.089 57 6 0.105 1
ZBED6 ZBED6 P86452 Zinc finger BED domain-containing protein 6 chr1 GO:0010817 Not Cancer Driver No 3 0.003 278 2 0.007 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0010817 Not Cancer Driver No 67 0.141 23 0 0.0 3