Total number of protein in "GO:0010769" GO term: 93
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0010769 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ACTN4 | ACTN4 | O43707 | Alpha-actinin-4 | chr19 | GO:0010769 | Not Cancer Driver | No | 131 | 0.144 | 244 | 42 | 0.172 | 8 |
| ACTR2_ENST00000260641 | ACTR2 | P61160 | Actin-related protein 2 | chr2 | GO:0010769 | Not Cancer Driver | No | 51 | 0.129 | 6 | 2 | 0.333 | 0 |
| ANAPC2 | ANAPC2 | Q9UJX6 | Anaphase-promoting complex subunit 2 | chr9 | GO:0010769 | Not Cancer Driver | No | 104 | 0.127 | 146 | 26 | 0.178 | 0 |
| ANKRD27 | ANKRD27 | Q96NW4 | Ankyrin repeat domain-containing protein 27 | chr19 | GO:0010769 | Not Cancer Driver | No | 145 | 0.138 | 239 | 33 | 0.138 | 0 |
| AP1AR | AP1AR | Q63HQ0 | AP-1 complex-associated regulatory protein | chr4 | GO:0010769 | Not Cancer Driver | No | 24 | 0.079 | 257 | 24 | 0.093 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0010769 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| ARHGEF7 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | GO:0010769 | Not Cancer Driver | No | 106 | 0.132 | 301 | 39 | 0.13 | 0 |
| ARPC2_ENST00000315717 | ARPC2 | O15144 | Actin-related protein 2/3 complex subunit 2 | chr2 | GO:0010769 | Not Cancer Driver | No | 40 | 0.133 | 49 | 8 | 0.163 | 0 |
| BAIAP2 | BAIAP2 | Q9UQB8 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | chr17 | GO:0010769 | Not Cancer Driver | No | 85 | 0.154 | 330 | 52 | 0.158 | 0 |
| BHLHB9 | BHLHB9 | Q6PI77 | Protein BHLHb9 | chrX | GO:0010769 | Not Cancer Driver | No | 88 | 0.161 | 267 | 38 | 0.142 | 0 |
| C1QBP | C1QBP | Q07021 | Complement component 1 Q subcomponent-binding protein, mitochondrial | chr17 | GO:0010769 | Not Cancer Driver | No | 14 | 0.05 | 103 | 6 | 0.058 | 2 |
| CALR | CALR | P27797 | Calreticulin | chr19 | GO:0010769 | Census | Yes | 45 | 0.108 | 245 | 31 | 0.127 | 0 |
| CAMK2B | CAMK2B | Q13554 | Calcium/calmodulin-dependent protein kinase type II subunit beta | chr7 | GO:0010769 | Not Cancer Driver | No | 86 | 0.129 | 273 | 28 | 0.103 | 6 |
| CAPRIN1_ENST00000532820 | CAPRIN1 | Q14444 | Caprin-1 | chr11 | GO:0010769 | Not Cancer Driver | No | 84 | 0.118 | 603 | 72 | 0.119 | 0 |
| CARMIL1 | CARMIL1 | Q5VZK9 | F-actin-uncapping protein LRRC16A | chr6 | GO:0010769 | Not Cancer Driver | No | 171 | 0.125 | 537 | 87 | 0.162 | 0 |
| CASS4 | CASS4 | Q9NQ75 | Cas scaffolding protein family member 4 | chr20 | GO:0010769 | Not Cancer Driver | No | 204 | 0.26 | 496 | 137 | 0.276 | 0 |
| CDC42_ENST00000344548 | CDC42 | P60953 | Cell division control protein 42 homolog | chr1 | GO:0010769 | Not Cancer Driver | No | 39 | 0.204 | 23 | 2 | 0.087 | 1 |
| CDKL3 | CDKL3 | Q8IVW4 | Cyclin-dependent kinase-like 3 | chr5 | GO:0010769 | Not Cancer Driver | No | 68 | 0.115 | 278 | 40 | 0.144 | 0 |
| CDKL5_ENST00000623535 | CDKL5 | O76039 | Cyclin-dependent kinase-like 5 | chrX | GO:0010769 | Not Cancer Driver | No | 165 | 0.172 | 685 | 120 | 0.175 | 18 |
| CIB1_ENST00000328649 | CIB1 | Q99828 | Calcium and integrin-binding protein 1 | chr15 | GO:0010769 | Not Cancer Driver | No | 24 | 0.126 | 6 | 1 | 0.167 | 0 |
| CNTN2 | CNTN2 | Q02246 | Contactin-2 | chr1 | GO:0010769 | Not Cancer Driver | No | 155 | 0.149 | 370 | 61 | 0.165 | 0 |
| CORO1C_ENST00000541050 | CORO1C | Q9ULV4 | Coronin-1C | chr12 | GO:0010769 | Not Cancer Driver | No | 61 | 0.129 | 84 | 13 | 0.155 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0010769 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0010769 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| CSPG5 | CSPG5 | O95196 | Chondroitin sulfate proteoglycan 5 | chr3 | GO:0010769 | Not Cancer Driver | No | 75 | 0.133 | 397 | 46 | 0.116 | 0 |
| CUL7_ENST00000265348 | CUL7 | Q14999 | Cullin-7 | chr6 | GO:0010769 | Not Cancer Driver | No | 188 | 0.111 | 372 | 41 | 0.11 | 3 |
| CUX2 | CUX2 | O14529 | Homeobox protein cut-like 2 | chr12 | GO:0010769 | Not Cancer Driver | No | 277 | 0.186 | 1201 | 212 | 0.177 | 1 |
| DAB2 | DAB2 | P98082 | Disabled homolog 2 | chr5 | GO:0010769 | Not Cancer Driver | No | 144 | 0.187 | 680 | 125 | 0.184 | 0 |
| DBN1_ENST00000309007 | DBN1 | Q16643 | Drebrin | chr5 | GO:0010769 | Not Cancer Driver | No | 84 | 0.129 | 510 | 73 | 0.143 | 0 |
| DBNL_ENST00000448521 | DBNL | Q9UJU6 | Drebrin-like protein | chr7 | GO:0010769 | Not Cancer Driver | No | 46 | 0.107 | 304 | 31 | 0.102 | 0 |
| DHX36 | DHX36 | Q9H2U1 | ATP-dependent DNA/RNA helicase DHX36 | chr3 | GO:0010769 | Not Cancer Driver | No | 159 | 0.158 | 222 | 39 | 0.176 | 0 |
| DMTN_ENST00000358242 | DMTN | Q08495 | Dematin | chr8 | GO:0010769 | Not Cancer Driver | No | 53 | 0.131 | 348 | 46 | 0.132 | 0 |
| DNM2_ENST00000355667 | DNM2 | P50570 | Dynamin-2 | chr19 | GO:0010769 | Census | Yes | 138 | 0.159 | 270 | 43 | 0.159 | 22 |
| DOCK1_ENST00000280333 | DOCK1 | Q14185 | Dedicator of cytokinesis protein 1 | chr10 | GO:0010769 | Not Cancer Driver | No | 240 | 0.129 | 360 | 52 | 0.144 | 0 |
| DOCK5 | DOCK5 | Q9H7D0 | Dedicator of cytokinesis protein 5 | chr8 | GO:0010769 | Not Cancer Driver | No | 278 | 0.149 | 330 | 45 | 0.136 | 0 |
| EEF2K | EEF2K | O00418 | Eukaryotic elongation factor 2 kinase | chr16 | GO:0010769 | Not Cancer Driver | No | 104 | 0.143 | 311 | 39 | 0.125 | 0 |
| EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0010769 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0010769 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0010769 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| FBLN1 | FBLN1 | P23142 | Fibulin-1 | chr22 | GO:0010769 | Compendium | Yes | 122 | 0.174 | 22 | 3 | 0.136 | 0 |
| FBXO31 | FBXO31 | Q5XUX0 | F-box only protein 31 | chr16 | GO:0010769 | Not Cancer Driver | No | 72 | 0.134 | 231 | 30 | 0.13 | 0 |
| FBXW8 | FBXW8 | Q8N3Y1 | F-box/WD repeat-containing protein 8 | chr12 | GO:0010769 | Not Cancer Driver | No | 68 | 0.114 | 120 | 4 | 0.033 | 0 |
| FERMT2_ENST00000395631 | FERMT2 | Q96AC1 | Fermitin family homolog 2 | chr14 | GO:0010769 | Not Cancer Driver | No | 71 | 0.104 | 101 | 10 | 0.099 | 0 |
| FGA | FGA | P02671 | Fibrinogen alpha chain | chr4 | GO:0010769 | Not Cancer Driver | No | 245 | 0.283 | 522 | 149 | 0.285 | 7 |
| FGB | FGB | P02675 | Fibrinogen beta chain | chr4 | GO:0010769 | Not Cancer Driver | No | 89 | 0.181 | 143 | 29 | 0.203 | 7 |
| FGG | FGG | P02679 | Fibrinogen gamma chain | chr4 | GO:0010769 | Not Cancer Driver | No | 81 | 0.179 | 53 | 8 | 0.151 | 8 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0010769 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| GBP1 | GBP1 | P32455 | Guanylate-binding protein 1 | chr1 | GO:0010769 | Not Cancer Driver | No | 92 | 0.155 | 166 | 27 | 0.163 | 0 |
| HAS2 | HAS2 | Q92819 | Hyaluronan synthase 2 | chr8 | GO:0010769 | Not Cancer Driver | No | 100 | 0.181 | 17 | 7 | 0.412 | 0 |
| IL1RAPL1 | IL1RAPL1 | Q9NZN1 | Interleukin-1 receptor accessory protein-like 1 | chrX | GO:0010769 | Not Cancer Driver | No | 205 | 0.295 | 77 | 19 | 0.247 | 0 |
| ILK_ENST00000299421 | ILK | Q13418 | Integrin-linked protein kinase | chr11 | GO:0010769 | Not Cancer Driver | No | 45 | 0.1 | 71 | 9 | 0.127 | 0 |
| ITGB1BP1_ENST00000355346 | ITGB1BP1 | O14713 | Integrin beta-1-binding protein 1 | chr2 | GO:0010769 | Not Cancer Driver | No | 26 | 0.13 | 58 | 11 | 0.19 | 0 |
| ITPKA | ITPKA | P23677 | Inositol-trisphosphate 3-kinase A | chr15 | GO:0010769 | Not Cancer Driver | No | 28 | 0.061 | 216 | 7 | 0.032 | 0 |
| KANK1_ENST00000382303 | KANK1 | Q14678 | KN motif and ankyrin repeat domain-containing protein 1 | chr9 | GO:0010769 | Not Cancer Driver | No | 183 | 0.135 | 804 | 100 | 0.124 | 0 |
| LIMS1_ENST00000393310 | LIMS1 | P48059 | LIM and senescent cell antigen-like-containing domain protein 1 | chr2 | GO:0010769 | Not Cancer Driver | No | 34 | 0.105 | 0 | 0 | 0.0 | 0 |
| LIMS2_ENST00000355119 | LIMS2 | Q7Z4I7 | LIM and senescent cell antigen-like-containing domain protein 2 | chr2 | GO:0010769 | Not Cancer Driver | No | 55 | 0.161 | 8 | 0 | 0.0 | 0 |
| LRP8 | LRP8 | Q14114 | Low-density lipoprotein receptor-related protein 8 | chr1 | GO:0010769 | Not Cancer Driver | No | 94 | 0.098 | 190 | 24 | 0.126 | 0 |
| MDK_ENST00000407067 | MDK | P21741 | Midkine | chr11 | GO:0010769 | Not Cancer Driver | No | 15 | 0.105 | 20 | 2 | 0.1 | 0 |
| MELTF | MELTF | P08582 | Melanotransferrin | chr3 | GO:0010769 | Not Cancer Driver | No | 106 | 0.144 | 23 | 6 | 0.261 | 0 |
| MPL | MPL | P40238 | Thrombopoietin receptor | chr1 | GO:0010769 | Census | Yes | 77 | 0.121 | 129 | 19 | 0.147 | 14 |
| MYADM | MYADM | Q96S97 | Myeloid-associated differentiation marker | chr19 | GO:0010769 | Not Cancer Driver | No | 73 | 0.227 | 0 | 0 | 0.0 | 0 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0010769 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| NEDD9 | NEDD9 | Q14511 | Enhancer of filamentation 1 | chr6 | GO:0010769 | Not Cancer Driver | No | 106 | 0.127 | 516 | 72 | 0.14 | 0 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0010769 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| OBSL1 | OBSL1 | O75147 | Obscurin-like protein 1 | chr2 | GO:0010769 | Not Cancer Driver | No | 233 | 0.123 | 553 | 60 | 0.108 | 0 |
| OLFM4 | OLFM4 | Q6UX06 | Olfactomedin-4 | chr13 | GO:0010769 | Not Cancer Driver | No | 117 | 0.229 | 54 | 11 | 0.204 | 0 |
| P4HB | P4HB | P07237 | Protein disulfide-isomerase | chr17 | GO:0010769 | Not Cancer Driver | No | 61 | 0.12 | 79 | 15 | 0.19 | 1 |
| PAFAH1B1 | PAFAH1B1 | P43034 | Platelet-activating factor acetylhydrolase IB subunit beta | chr17 | GO:0010769 | Not Cancer Driver | No | 42 | 0.102 | 82 | 11 | 0.134 | 7 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0010769 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PARP6 | PARP6 | Q2NL67 | Protein mono-ADP-ribosyltransferase PARP6 | chr15 | GO:0010769 | Not Cancer Driver | No | 87 | 0.138 | 67 | 13 | 0.194 | 0 |
| PDPN_ENST00000621990 | PDPN | Q86YL7 | Podoplanin | chr1 | GO:0010769 | Not Cancer Driver | No | 37 | 0.228 | 96 | 24 | 0.25 | 0 |
| PREX1 | PREX1 | Q8TCU6 | Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein | chr20 | GO:0010769 | Not Cancer Driver | No | 297 | 0.179 | 307 | 55 | 0.179 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0010769 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0010769 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| PTPRD | PTPRD | P23468 | Receptor-type tyrosine-protein phosphatase delta | chr9 | GO:0010769 | Census, Compendium | Yes | 577 | 0.302 | 747 | 219 | 0.293 | 0 |
| RAB21 | RAB21 | Q9UL25 | Ras-related protein Rab-21 | chr12 | GO:0010769 | Not Cancer Driver | No | 23 | 0.102 | 59 | 4 | 0.068 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0010769 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RAC3 | RAC3 | P60763 | Ras-related C3 botulinum toxin substrate 3 | chr17 | GO:0010769 | Not Cancer Driver | No | 24 | 0.125 | 0 | 0 | 0.0 | 4 |
| RCC2 | RCC2 | Q9P258 | Protein RCC2 | chr1 | GO:0010769 | Not Cancer Driver | No | 63 | 0.121 | 194 | 27 | 0.139 | 0 |
| RELN | RELN | P78509 | Reelin | chr7 | GO:0010769 | Not Cancer Driver | No | 761 | 0.22 | 107 | 19 | 0.178 | 7 |
| RREB1_ENST00000349384 | RREB1 | Q92766 | Ras-responsive element-binding protein 1 | chr6 | GO:0010769 | Not Cancer Driver | No | 213 | 0.126 | 1152 | 144 | 0.125 | 0 |
| S100A10 | S100A10 | P60903 | Protein S100-A10 | chr1 | GO:0010769 | Not Cancer Driver | No | 11 | 0.113 | 3 | 1 | 0.333 | 0 |
| SPRY4_ENST00000434127 | SPRY4 | Q9C004 | Protein sprouty homolog 4 | chr5 | GO:0010769 | Not Cancer Driver | No | 34 | 0.114 | 134 | 20 | 0.149 | 7 |
| SS18L1 | SS18L1 | O75177 | Calcium-responsive transactivator | chr20 | GO:0010769 | Census | Yes | 53 | 0.134 | 356 | 48 | 0.135 | 0 |
| SS18L2 | SS18L2 | Q9UHA2 | SS18-like protein 2 | chr3 | GO:0010769 | Not Cancer Driver | No | 4 | 0.052 | 7 | 1 | 0.143 | 0 |
| ST6GAL1 | ST6GAL1 | P15907 | Beta-galactoside alpha-2,6-sialyltransferase 1 | chr3 | GO:0010769 | Not Cancer Driver | No | 55 | 0.135 | 34 | 8 | 0.235 | 0 |
| STAU2 | STAU2 | Q9NUL3 | Double-stranded RNA-binding protein Staufen homolog 2 | chr8 | GO:0010769 | Not Cancer Driver | No | 68 | 0.119 | 486 | 54 | 0.111 | 0 |
| TACSTD2 | TACSTD2 | P09758 | Tumor-associated calcium signal transducer 2 | chr1 | GO:0010769 | Not Cancer Driver | No | 22 | 0.068 | 27 | 1 | 0.037 | 0 |
| TESK1_ENST00000336395 | TESK1 | Q15569 | Dual specificity testis-specific protein kinase 1 | chr9 | GO:0010769 | Not Cancer Driver | No | 63 | 0.101 | 339 | 35 | 0.103 | 0 |
| TRIOBP_ENST00000644935 | TRIOBP | Q9H2D6 | TRIO and F-actin-binding protein | chr22 | GO:0010769 | Not Cancer Driver | No | 386 | 0.163 | 2196 | 370 | 0.168 | 1 |
| UNC13D | UNC13D | Q70J99 | Protein unc-13 homolog D | chr17 | GO:0010769 | Not Cancer Driver | No | 120 | 0.11 | 248 | 30 | 0.121 | 0 |
| WASHC2C_ENST00000374362 | WASHC2C | Q9Y4E1 | WASH complex subunit 2C | chr10 | GO:0010769 | Not Cancer Driver | No | 90 | 0.068 | 1204 | 89 | 0.074 | 0 |