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Total number of protein in "GO:0010639" GO term:  271

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACAA2 ACAA2 P42765 3-ketoacyl-CoA thiolase, mitochondrial chr18 GO:0010639 Not Cancer Driver No 42 0.106 51 2 0.039 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0010639 Not Cancer Driver No 49 0.107 256 34 0.133 1
ADCK1 ADCK1 Q86TW2 AarF domain-containing protein kinase 1 chr14 GO:0010639 Not Cancer Driver No 82 0.155 6 3 0.5 0
ADD1_ENST00000398129 ADD1 P35611 Alpha-adducin chr4 GO:0010639 Not Cancer Driver No 106 0.144 439 64 0.146 0
ADD2_ENST00000407644 ADD2 P35612 Beta-adducin chr2 GO:0010639 Not Cancer Driver No 157 0.216 423 104 0.246 0
ADD3 ADD3 Q9UEY8 Gamma-adducin chr10 GO:0010639 Not Cancer Driver No 95 0.135 381 48 0.126 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0010639 Census, Compendium Yes 108 0.225 158 24 0.152 4
ANKRD27 ANKRD27 Q96NW4 Ankyrin repeat domain-containing protein 27 chr19 GO:0010639 Not Cancer Driver No 145 0.138 239 33 0.138 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0010639 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0010639 Not Cancer Driver No 117 0.051 1725 78 0.045 0
ARAP1 ARAP1 Q96P48 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 chr11 GO:0010639 Not Cancer Driver No 152 0.105 401 28 0.07 0
ARHGAP28_ENST00000383472 ARHGAP28 Q9P2N2 Rho GTPase-activating protein 28 chr18 GO:0010639 Not Cancer Driver No 121 0.166 336 45 0.134 0
ARHGAP6 ARHGAP6 O43182 Rho GTPase-activating protein 6 chrX GO:0010639 Not Cancer Driver No 168 0.172 680 118 0.174 0
ARHGEF2 ARHGEF2 Q92974 Rho guanine nucleotide exchange factor 2 chr1 GO:0010639 Not Cancer Driver No 146 0.148 450 70 0.156 0
ARHGEF7 ARHGEF7 Q14155 Rho guanine nucleotide exchange factor 7 chr13 GO:0010639 Not Cancer Driver No 106 0.132 301 39 0.13 0
ARPIN ARPIN Q7Z6K5 Arpin chr15 GO:0010639 Not Cancer Driver No 26 0.115 110 14 0.127 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0010639 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0010639 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0010639 Census, Compendium Yes 487 0.195 1672 301 0.18 33
ATXN7_ENST00000487717 ATXN7 O15265 Ataxin-7 chr3 GO:0010639 Not Cancer Driver No 95 0.107 797 82 0.103 0
AVIL AVIL O75366 Advillin chr12 GO:0010639 Not Cancer Driver No 91 0.111 138 17 0.123 2
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0010639 Not Cancer Driver No 14 0.085 26 0 0.0 39
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0010639 Not Cancer Driver No 153 0.103 840 87 0.104 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0010639 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0010639 Not Cancer Driver No 22 0.114 34 6 0.176 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0010639 Not Cancer Driver No 45 0.1 190 19 0.1 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0010639 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0010639 Census, Compendium Yes 224 0.12 1458 174 0.119 35
C11orf65 MFI Q8NCR3 Protein MFI chr11 GO:0010639 Not Cancer Driver No 42 0.134 66 7 0.106 0
C16orf45 BMERB1 Q96MC5 bMERB domain-containing protein 1 chr16 GO:0010639 Not Cancer Driver No 32 0.157 102 16 0.157 0
CAMSAP1 CAMSAP1 Q5T5Y3 Calmodulin-regulated spectrin-associated protein 1 chr9 GO:0010639 Not Cancer Driver No 208 0.13 1129 158 0.14 0
CAMSAP2 CAMSAP2 Q08AD1 Calmodulin-regulated spectrin-associated protein 2 chr1 GO:0010639 Not Cancer Driver No 176 0.118 1025 127 0.124 0
CAMSAP3_ENST00000160298 CAMSAP3 Q9P1Y5 Calmodulin-regulated spectrin-associated protein 3 chr19 GO:0010639 Not Cancer Driver No 132 0.106 889 81 0.091 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0010639 Not Cancer Driver No 45 0.129 95 7 0.074 0
CAPZA1 CAPZA1 P52907 F-actin-capping protein subunit alpha-1 chr1 GO:0010639 Not Cancer Driver No 40 0.14 41 2 0.049 0
CAPZA2 CAPZA2 P47755 F-actin-capping protein subunit alpha-2 chr7 GO:0010639 Not Cancer Driver No 37 0.129 19 0 0.0 0
CAPZA3 CAPZA3 Q96KX2 F-actin-capping protein subunit alpha-3 chr12 GO:0010639 Not Cancer Driver No 87 0.291 0 0 0.0 0
CAPZB_ENST00000375142 CAPZB P47756 F-actin-capping protein subunit beta chr1 GO:0010639 Not Cancer Driver No 33 0.119 66 3 0.045 0
CAV3 CAV3 P56539 Caveolin-3 chr3 GO:0010639 Not Cancer Driver No 27 0.179 0 0 0.0 25
CCNF CCNF P41002 Cyclin-F chr16 GO:0010639 Not Cancer Driver No 106 0.135 221 23 0.104 3
CCP110 CCP110 O43303 Centriolar coiled-coil protein of 110 kDa chr16 GO:0010639 Not Cancer Driver No 94 0.093 679 61 0.09 0
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0010639 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK10 CDK10 Q15131 Cyclin-dependent kinase 10 chr16 GO:0010639 Not Cancer Driver No 42 0.117 30 4 0.133 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0010639 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CEP97 CEP97 Q8IW35 Centrosomal protein of 97 kDa chr3 GO:0010639 Not Cancer Driver No 95 0.11 405 41 0.101 0
CGNL1 CGNL1 Q0VF96 Cingulin-like protein 1 chr15 GO:0010639 Not Cancer Driver No 191 0.147 1223 182 0.149 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:0010639 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:0010639 Not Cancer Driver No 25 0.112 201 22 0.109 2
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0010639 Not Cancer Driver No 24 0.126 6 1 0.167 0
CKAP2 CKAP2 Q8WWK9 Cytoskeleton-associated protein 2 chr13 GO:0010639 Not Cancer Driver No 72 0.105 522 57 0.109 0
CLASP1_ENST00000646274 CLASP1 Q7Z460 CLIP-associating protein 1 chr2 GO:0010639 Not Cancer Driver No 163 0.106 642 70 0.109 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0010639 Not Cancer Driver No 158 0.122 676 94 0.139 0
CLIP3_ENST00000593074 CLIP3 Q96DZ5 CAP-Gly domain-containing linker protein 3 chr19 GO:0010639 Not Cancer Driver No 78 0.143 218 22 0.101 0
CLU_ENST00000523500 CLU P10909 Clusterin chr8 GO:0010639 Not Cancer Driver No 69 0.154 156 27 0.173 0
CORO1A CORO1A P31146 Coronin-1A chr16 GO:0010639 Not Cancer Driver No 51 0.111 126 15 0.119 1
CORO1B CORO1B Q9BR76 Coronin-1B chr11 GO:0010639 Not Cancer Driver No 41 0.084 138 10 0.072 0
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 GO:0010639 Not Cancer Driver No 85 0.177 37 7 0.189 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0010639 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTNNA2 CTNNA2 P26232 Catenin alpha-2 chr2 GO:0010639 Census Yes 387 0.406 307 130 0.423 0
DCP2 DCP2 Q8IU60 m7GpppN-mRNA hydrolase chr5 GO:0010639 Not Cancer Driver No 57 0.136 167 24 0.144 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0010639 Not Cancer Driver No 331 0.217 922 237 0.257 0
DMRT1 DMRT1 Q9Y5R6 Doublesex- and mab-3-related transcription factor 1 chr9 GO:0010639 Not Cancer Driver No 60 0.161 282 47 0.167 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0010639 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0010639 Census Yes 138 0.159 270 43 0.159 22
DYRK1A_ENST00000644942 DYRK1A Q13627 Dual specificity tyrosine-phosphorylation-regulated kinase 1A chr21 GO:0010639 Not Cancer Driver No 135 0.177 447 73 0.163 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0010639 Not Cancer Driver No 142 0.117 585 71 0.121 0
EML2_ENST00000245925 EML2 O95834 Echinoderm microtubule-associated protein-like 2 chr19 GO:0010639 Not Cancer Driver No 97 0.149 20 3 0.15 0
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0010639 Not Cancer Driver No 106 0.129 459 54 0.118 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0010639 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0010639 Census Yes 120 0.131 225 27 0.12 15
ESPL1 ESPL1 Q14674 Separin chr12 GO:0010639 Not Cancer Driver No 211 0.1 380 39 0.103 0
EVI5L_ENST00000270530 EVI5L Q96CN4 EVI5-like protein chr19 GO:0010639 Not Cancer Driver No 70 0.088 381 27 0.071 0
EXOSC10 EXOSC10 Q01780 Exosome component 10 chr1 GO:0010639 Not Cancer Driver No 87 0.098 375 35 0.093 0
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0010639 Not Cancer Driver No 47 0.157 72 15 0.208 0
FBXO43 FBXO43 Q4G163 F-box only protein 43 chr8 GO:0010639 Not Cancer Driver No 98 0.138 292 40 0.137 0
FBXO5 FBXO5 Q9UKT4 F-box only protein 5 chr6 GO:0010639 Not Cancer Driver No 48 0.107 113 13 0.115 0
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0010639 Not Cancer Driver No 66 0.168 277 49 0.177 0
FEZ2_ENST00000405912 FEZ2 Q9UHY8 Fasciculation and elongation protein zeta-2 chr2 GO:0010639 Not Cancer Driver No 37 0.105 245 29 0.118 0
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0010639 Not Cancer Driver No 70 0.286 96 33 0.344 2
FKBP4 FKBP4 Q02790 Peptidyl-prolyl cis-trans isomerase FKBP4 chr12 GO:0010639 Not Cancer Driver No 46 0.1 134 12 0.09 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0010639 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLII FLII Q13045 Protein flightless-1 homolog chr17 GO:0010639 Not Cancer Driver No 128 0.101 206 32 0.155 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0010639 Not Cancer Driver No 147 0.206 256 59 0.23 25
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0010639 Not Cancer Driver No 16 0.076 73 0 0.0 8
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0010639 Not Cancer Driver No 55 0.093 61 0 0.0 0
GCLC GCLC P48506 Glutamate--cysteine ligase catalytic subunit chr6 GO:0010639 Not Cancer Driver No 73 0.115 167 18 0.108 3
GDI2 GDI2 P50395 Rab GDP dissociation inhibitor beta chr10 GO:0010639 Not Cancer Driver No 49 0.11 23 2 0.087 0
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 GO:0010639 Not Cancer Driver No 50 0.145 8 0 0.0 0
GMFB GMFB P60983 Glia maturation factor beta chr14 GO:0010639 Not Cancer Driver No 18 0.127 11 0 0.0 0
GMFG GMFG O60234 Glia maturation factor gamma chr19 GO:0010639 Not Cancer Driver No 22 0.155 10 0 0.0 0
GNL3L_ENST00000360845 GNL3L Q9NVN8 Guanine nucleotide-binding protein-like 3-like protein chrX GO:0010639 Not Cancer Driver No 120 0.206 242 43 0.178 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0010639 Not Cancer Driver No 38 0.187 12 1 0.083 0
GSN GSN P06396 Gelsolin chr9 GO:0010639 Not Cancer Driver No 76 0.097 316 28 0.089 2
H3F3A_ENST00000366816 H3-3B P84243 Histone H3.3 chr1 GO:0010639 Not Cancer Driver No 32 0.235 51 22 0.431 3
H3F3B_ENST00000589599 H3-3B P84243 Histone H3.3 chr17 GO:0010639 Not Cancer Driver No 28 0.206 51 14 0.275 3
HDAC6_ENST00000426196 HDAC6 Q9UBN7 Histone deacetylase 6 chrX GO:0010639 Not Cancer Driver No 178 0.147 409 59 0.144 0
HDGFL3 HDGFL3 Q9Y3E1 Hepatoma-derived growth factor-related protein 3 chr15 GO:0010639 Not Cancer Driver No 25 0.123 163 18 0.11 0
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0010639 Compendium Yes 233 0.32 43 16 0.372 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0010639 Not Cancer Driver No 94 0.088 524 34 0.065 0
HNRNPA1 HNRNPA1 P09651 Heterogeneous nuclear ribonucleoprotein A1 chr12 GO:0010639 Not Cancer Driver No 70 0.188 290 58 0.2 4
HNRNPC_ENST00000420743 HNRNPC P07910 Heterogeneous nuclear ribonucleoproteins C1/C2 chr14 GO:0010639 Not Cancer Driver No 42 0.137 227 35 0.154 0
HNRNPU HNRNPU Q00839 Heterogeneous nuclear ribonucleoprotein U chr1 GO:0010639 Not Cancer Driver No 77 0.093 504 45 0.089 0
HORMAD1 HORMAD1 Q86X24 HORMA domain-containing protein 1 chr1 GO:0010639 Not Cancer Driver No 76 0.193 178 31 0.174 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0010639 Not Cancer Driver No 24 0.037 200 13 0.065 0
HUWE1_ENST00000262854 HUWE1 Q7Z6Z7 E3 ubiquitin-protein ligase HUWE1 chrX GO:0010639 Not Cancer Driver No 669 0.153 2091 329 0.157 21
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0010639 Not Cancer Driver No 22 0.247 10 2 0.2 0
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0010639 Not Cancer Driver No 45 0.231 87 23 0.264 0
INPP5J INPP5J Q15735 Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A chr22 GO:0010639 Not Cancer Driver No 102 0.101 629 42 0.067 0
INPP5K INPP5K Q9BT40 Inositol polyphosphate 5-phosphatase K chr17 GO:0010639 Not Cancer Driver No 42 0.094 34 2 0.059 7
IQCJ-SCHIP1 IQCJ-SCHIP1 B3KU38 IQCJ-SCHIP1 readthrough transcript protein chr3 GO:0010639 Not Cancer Driver No 76 0.135 517 71 0.137 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0010639 Not Cancer Driver No 88 0.105 251 17 0.068 0
KAT2B KAT2B Q92831 Histone acetyltransferase KAT2B chr3 GO:0010639 Not Cancer Driver No 107 0.129 266 27 0.102 0
KATNB1 KATNB1 Q9BVA0 Katanin p80 WD40 repeat-containing subunit B1 chr16 GO:0010639 Not Cancer Driver No 70 0.107 179 24 0.134 3
KIF24 KIF24 Q5T7B8 Kinesin-like protein KIF24 chr9 GO:0010639 Not Cancer Driver No 126 0.092 898 90 0.1 0
LIF LIF P15018 Leukemia inhibitory factor chr22 GO:0010639 Not Cancer Driver No 25 0.124 0 0 0.0 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0010639 Not Cancer Driver No 148 0.248 235 50 0.213 0
LIMA1_ENST00000341247 LIMA1 Q9UHB6 LIM domain and actin-binding protein 1 chr12 GO:0010639 Not Cancer Driver No 88 0.116 687 81 0.118 0
LIMK2_ENST00000331728 LIMK2 P53671 LIM domain kinase 2 chr22 GO:0010639 Not Cancer Driver No 93 0.146 146 29 0.199 0
LMNA LMNA P02545 Prelamin-A/C chr1 GO:0010639 Census Yes 68 0.102 544 49 0.09 131
LMOD1 LMOD1 P29536 Leiomodin-1 chr1 GO:0010639 Not Cancer Driver No 97 0.162 499 80 0.16 0
LMOD2 LMOD2 Q6P5Q4 Leiomodin-2 chr7 GO:0010639 Not Cancer Driver No 94 0.172 451 79 0.175 0
LMOD3_ENST00000489031 LMOD3 Q0VAK6 Leiomodin-3 chr3 GO:0010639 Not Cancer Driver No 99 0.177 456 84 0.184 1
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0010639 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAK_ENST00000474039 MAK P20794 Serine/threonine-protein kinase MAK chr6 GO:0010639 Not Cancer Driver No 80 0.128 323 51 0.158 5
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0010639 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP2 MAP2 P11137 Microtubule-associated protein 2 chr2 GO:0010639 Compendium Yes 367 0.201 1726 340 0.197 0
MAP4 MAP4 P27816 Microtubule-associated protein 4 chr3 GO:0010639 Not Cancer Driver No 116 0.101 1136 114 0.1 0
MAP6D1 MAP6D1 Q9H9H5 MAP6 domain-containing protein 1 chr3 GO:0010639 Not Cancer Driver No 8 0.04 173 8 0.046 0
MAPRE1 MAPRE1 Q15691 Microtubule-associated protein RP/EB family member 1 chr20 GO:0010639 Not Cancer Driver No 26 0.097 109 11 0.101 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0010639 Not Cancer Driver No 128 0.169 750 126 0.168 18
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0010639 Not Cancer Driver No 104 0.115 275 38 0.138 1
MDM1 MDM1 Q8TC05 Nuclear protein MDM1 chr12 GO:0010639 Not Cancer Driver No 105 0.147 661 101 0.153 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0010639 Census, Compendium Yes 226 0.163 62 15 0.242 19
MID1 MID1 O15344 E3 ubiquitin-protein ligase Midline-1 chrX GO:0010639 Not Cancer Driver No 86 0.129 86 16 0.186 4
MID1IP1_ENST00000336949 MID1IP1 Q9NPA3 Mid1-interacting protein 1 chrX GO:0010639 Not Cancer Driver No 23 0.126 83 6 0.072 0
MNAT1 MNAT1 P51948 CDK-activating kinase assembly factor MAT1 chr14 GO:0010639 Not Cancer Driver No 23 0.074 64 2 0.031 0
MPV17L MPV17L Q2QL34 Mpv17-like protein chr16 GO:0010639 Not Cancer Driver No 16 0.082 3 0 0.0 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:0010639 Not Cancer Driver No 112 0.186 79 9 0.114 57
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0010639 Not Cancer Driver No 48 0.136 16 2 0.125 0
MYOC MYOC Q99972 Myocilin chr1 GO:0010639 Not Cancer Driver No 92 0.183 196 43 0.219 58
NAA10 NAA10 P41227 N-alpha-acetyltransferase 10 chrX GO:0010639 Not Cancer Driver No 33 0.14 117 17 0.145 3
NANOS2 NANOS2 P60321 Nanos homolog 2 chr19 GO:0010639 Not Cancer Driver No 29 0.21 50 11 0.22 0
NAT10 NAT10 Q9H0A0 RNA cytidine acetyltransferase chr11 GO:0010639 Not Cancer Driver No 109 0.106 142 18 0.127 0
NAV3 NAV3 Q8IVL0 Neuron navigator 3 chr12 GO:0010639 Not Cancer Driver No 699 0.293 1823 548 0.301 0
NBDY_ENST00000423617 NBDY A0A0U1RRE5 Negative regulator of P-body association chrX GO:0010639 Not Cancer Driver No 2 0.029 68 2 0.029 0
NBN NBN O60934 Nibrin chr8 GO:0010639 Census Yes 90 0.119 417 54 0.129 1
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0010639 Not Cancer Driver No 20 0.096 179 17 0.095 2
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0010639 Census, Compendium Yes 29 0.099 249 22 0.088 0
NUBP1 NUBP1 P53384 Cytosolic Fe-S cluster assembly factor NUBP1 chr16 GO:0010639 Not Cancer Driver No 31 0.097 62 6 0.097 0
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0010639 Not Cancer Driver No 10 0.122 82 10 0.122 0
ODF2L_ENST00000317336 ODF2L Q9ULJ1 Protein BCAP chr1 GO:0010639 Not Cancer Driver No 58 0.091 186 25 0.134 0
OMA1 OMA1 Q96E52 Metalloendopeptidase OMA1, mitochondrial chr1 GO:0010639 Not Cancer Driver No 52 0.099 34 4 0.118 0
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0010639 Not Cancer Driver No 114 0.119 131 17 0.13 60
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0010639 Compendium Yes 89 0.17 242 49 0.202 0
PARL PARL Q9H300 Presenilins-associated rhomboid-like protein, mitochondrial chr3 GO:0010639 Not Cancer Driver No 49 0.129 28 5 0.179 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0010639 Not Cancer Driver No 119 0.117 320 34 0.106 0
PFN1 PFN1 P07737 Profilin-1 chr17 GO:0010639 Not Cancer Driver No 16 0.114 7 1 0.143 3
PFN4 PFN4 Q8NHR9 Profilin-4 chr2 GO:0010639 Not Cancer Driver No 17 0.132 0 0 0.0 0
PHF23 PHF23 Q9BUL5 PHD finger protein 23 chr17 GO:0010639 Not Cancer Driver No 45 0.112 331 37 0.112 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0010639 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0010639 Not Cancer Driver No 50 0.12 49 3 0.061 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0010639 Not Cancer Driver No 54 0.084 209 11 0.053 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0010639 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0010639 Census, Compendium Yes 154 0.213 268 61 0.228 2
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0010639 Not Cancer Driver No 57 0.098 99 13 0.131 23
PINX1 PINX1 Q96BK5 PIN2/TERF1-interacting telomerase inhibitor 1 chr8 GO:0010639 Not Cancer Driver No 66 0.201 328 66 0.201 0
PLEKHH2 PLEKHH2 Q8IVE3 Pleckstrin homology domain-containing family H member 2 chr2 GO:0010639 Not Cancer Driver No 219 0.147 653 101 0.155 0
POT1 POT1 Q9NUX5 Protection of telomeres protein 1 chr7 GO:0010639 Census, Compendium Yes 113 0.178 31 6 0.194 9
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0010639 Census Yes 72 0.143 44 4 0.091 3
PPFIA1 PPFIA1 Q13136 Liprin-alpha-1 chr11 GO:0010639 Not Cancer Driver No 164 0.136 865 126 0.146 0
PPIF PPIF P30405 Peptidyl-prolyl cis-trans isomerase F, mitochondrial chr10 GO:0010639 Not Cancer Driver No 19 0.092 43 4 0.093 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0010639 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0010639 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRRT2_ENST00000645336 PRRT2 Q7Z6L0 Proline-rich transmembrane protein 2 chr16 GO:0010639 Not Cancer Driver No 45 0.132 268 32 0.119 7
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0010639 Not Cancer Driver No 20 0.088 53 5 0.094 0
RAB7A RAB7A P51149 Ras-related protein Rab-7a chr3 GO:0010639 Not Cancer Driver No 27 0.13 11 0 0.0 4
RAD1 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:0010639 Not Cancer Driver No 29 0.103 4 1 0.25 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0010639 Not Cancer Driver No 157 0.12 730 84 0.115 0
RBM14 RBM14 Q96PK6 RNA-binding protein 14 chr11 GO:0010639 Not Cancer Driver No 99 0.148 350 59 0.169 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0010639 Not Cancer Driver No 71 0.122 297 37 0.125 1
RHPN1 RHPN1 Q8TCX5 Rhophilin-1 chr8 GO:0010639 Not Cancer Driver No 70 0.104 257 27 0.105 0
RHPN2 RHPN2 Q8IUC4 Rhophilin-2 chr19 GO:0010639 Compendium Yes 111 0.162 88 17 0.193 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0010639 Not Cancer Driver No 44 0.139 33 2 0.061 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0010639 Not Cancer Driver No 133 0.181 91 15 0.165 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0010639 Not Cancer Driver No 144 0.118 474 64 0.135 14
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0010639 Not Cancer Driver No 86 0.225 29 6 0.207 0
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 GO:0010639 Not Cancer Driver No 66 0.103 117 12 0.103 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0010639 Not Cancer Driver No 100 0.14 170 35 0.206 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0010639 Not Cancer Driver No 288 0.133 1659 186 0.112 0
SLC25A31 SLC25A31 Q9H0C2 ADP/ATP translocase 4 chr4 GO:0010639 Not Cancer Driver No 68 0.216 8 0 0.0 0
SLC25A4 SLC25A4 P12235 ADP/ATP translocase 1 chr4 GO:0010639 Not Cancer Driver No 24 0.081 0 0 0.0 9
SLC25A5 SLC25A5 P05141 ADP/ATP translocase 2 chrX GO:0010639 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX GO:0010639 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC35F6 SLC35F6 Q8N357 Solute carrier family 35 member F6 chr2 GO:0010639 Not Cancer Driver No 33 0.089 13 0 0.0 0
SLX1B SLX1B Q9BQ83 Structure-specific endonuclease subunit SLX1 chr16 GO:0010639 Not Cancer Driver No 3 0.011 80 1 0.013 0
SLX4 SLX4 Q8IY92 Structure-specific endonuclease subunit SLX4 chr16 GO:0010639 Not Cancer Driver No 271 0.148 1573 232 0.147 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0010639 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0010639 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0010639 Not Cancer Driver No 107 0.114 357 38 0.106 0
SMG6 SMG6 Q86US8 Telomerase-binding protein EST1A chr17 GO:0010639 Not Cancer Driver No 166 0.117 751 97 0.129 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0010639 Not Cancer Driver No 21 0.15 107 13 0.121 5
SPEF1 SPEF1 Q9Y4P9 Sperm flagellar protein 1 chr20 GO:0010639 Not Cancer Driver No 19 0.081 89 5 0.056 0
SPTA1_ENST00000368147 SPTA1 P02549 Spectrin alpha chain, erythrocytic 1 chr1 GO:0010639 Not Cancer Driver No 1046 0.432 707 294 0.416 21
SPTAN1_ENST00000372731 SPTAN1 Q13813 Spectrin alpha chain, non-erythrocytic 1 chr9 GO:0010639 Not Cancer Driver No 315 0.127 980 114 0.116 0
SPTBN1 SPTBN1 Q01082 Spectrin beta chain, non-erythrocytic 1 chr2 GO:0010639 Not Cancer Driver No 311 0.132 869 123 0.142 0
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0010639 Not Cancer Driver No 317 0.133 877 126 0.144 2
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0010639 Not Cancer Driver No 312 0.122 866 103 0.119 0
SPTBN5 SPTBN5 Q9NRC6 Spectrin beta chain, non-erythrocytic 5 chr15 GO:0010639 Not Cancer Driver No 314 0.085 1274 118 0.093 0
SPTB_ENST00000389721 SPTB P11277 Spectrin beta chain, erythrocytic chr14 GO:0010639 Not Cancer Driver No 328 0.153 562 70 0.125 7
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0010639 Census Yes 53 0.099 130 11 0.085 1
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0010639 Not Cancer Driver No 15 0.101 149 15 0.101 0
STMN2_ENST00000220876 STMN2 Q93045 Stathmin-2 chr8 GO:0010639 Not Cancer Driver No 34 0.19 122 23 0.189 0
STN1 STN1 Q9H668 CST complex subunit STN1 chr10 GO:0010639 Not Cancer Driver No 41 0.111 27 2 0.074 2
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0010639 Not Cancer Driver No 55 0.176 18 3 0.167 0
SVIL SVIL O95425 Supervillin chr10 GO:0010639 Not Cancer Driver No 308 0.139 1423 192 0.135 0
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0010639 Not Cancer Driver No 44 0.075 271 18 0.066 0
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0010639 Not Cancer Driver No 22 0.068 27 1 0.037 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0010639 Not Cancer Driver No 116 0.116 601 59 0.098 0
TBC1D4 TBC1D4 O60343 TBC1 domain family member 4 chr13 GO:0010639 Not Cancer Driver No 173 0.133 590 90 0.153 0
TBC1D7 TBC1D7 Q9P0N9 TBC1 domain family member 7 chr6 GO:0010639 Not Cancer Driver No 51 0.174 1 0 0.0 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 GO:0010639 Not Cancer Driver No 156 0.131 60 9 0.15 11
TCHP_ENST00000405876 TCHP Q9BT92 Trichoplein keratin filament-binding protein chr12 GO:0010639 Not Cancer Driver No 60 0.12 356 50 0.14 0
TEN1 TEN1 Q86WV5 CST complex subunit TEN1 chr17 GO:0010639 Not Cancer Driver No 6 0.049 8 4 0.5 0
TERF1 TERF1 P54274 Telomeric repeat-binding factor 1 chr8 GO:0010639 Not Cancer Driver No 63 0.144 220 34 0.155 0
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0010639 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0010639 Not Cancer Driver No 28 0.07 310 16 0.052 0
TESK1_ENST00000336395 TESK1 Q15569 Dual specificity testis-specific protein kinase 1 chr9 GO:0010639 Not Cancer Driver No 63 0.101 339 35 0.103 0
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0010639 Census Yes 89 0.117 80 6 0.075 1
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0010639 Not Cancer Driver No 44 0.163 39 9 0.231 0
TINF2 TINF2 Q9BSI4 TERF1-interacting nuclear factor 2 chr14 GO:0010639 Not Cancer Driver No 38 0.084 190 17 0.089 4
TJP1_ENST00000346128 TJP1 Q07157 Tight junction protein ZO-1 chr15 GO:0010639 Not Cancer Driver No 198 0.113 1350 151 0.112 0
TMEFF2 TMEFF2 Q9UIK5 Tomoregulin-2 chr2 GO:0010639 Not Cancer Driver No 81 0.217 68 8 0.118 0
TMEM14A TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 GO:0010639 Not Cancer Driver No 10 0.101 0 0 0.0 0
TMEM39A TMEM39A Q9NV64 Transmembrane protein 39A chr3 GO:0010639 Not Cancer Driver No 53 0.109 14 1 0.071 0
TMEM67 TMEM67 Q5HYA8 Meckelin chr8 GO:0010639 Not Cancer Driver No 120 0.121 11 0 0.0 37
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 GO:0010639 Not Cancer Driver No 41 0.114 195 29 0.149 0
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0010639 Not Cancer Driver No 33 0.094 216 22 0.102 0
TMOD3 TMOD3 Q9NYL9 Tropomodulin-3 chr15 GO:0010639 Not Cancer Driver No 40 0.114 190 24 0.126 0
TMOD4 TMOD4 Q9NZQ9 Tropomodulin-4 chr1 GO:0010639 Not Cancer Driver No 37 0.107 218 22 0.101 0
TMSB10 TMSB10 P63313 Thymosin beta-10 chr2 GO:0010639 Not Cancer Driver No 2 0.045 44 2 0.045 0
TMSB15A TMSB15A P0CG34 Thymosin beta-15A chrX GO:0010639 Not Cancer Driver No 8 0.178 45 8 0.178 0
TMSB15B TMSB15B P0CG35 Thymosin beta-15B chrX GO:0010639 Not Cancer Driver No 7 0.156 45 7 0.156 0
TMSB4X_ENST00000380633 TMSB4X P62328 Thymosin beta-4 chrX GO:0010639 Census Yes 7 0.159 44 7 0.159 0
TMSB4Y TMSB4Y O14604 Thymosin beta-4, Y-chromosomal chrY GO:0010639 Not Cancer Driver No 1 0.023 44 1 0.023 0
TNKS TNKS O95271 Poly [ADP-ribose] polymerase tankyrase-1 chr8 GO:0010639 Not Cancer Driver No 163 0.123 480 59 0.123 0
TNKS2 TNKS2 Q9H2K2 Poly [ADP-ribose] polymerase tankyrase-2 chr10 GO:0010639 Not Cancer Driver No 117 0.1 255 24 0.094 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0010639 Compendium Yes 150 0.098 508 59 0.116 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0010639 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPX2 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 GO:0010639 Not Cancer Driver No 92 0.123 695 86 0.124 0
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0010639 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM37 TRIM37 O94972 E3 ubiquitin-protein ligase TRIM37 chr17 GO:0010639 Not Cancer Driver No 119 0.123 492 60 0.122 3
TRIM54_ENST00000380075 TRIM54 Q9BYV2 Tripartite motif-containing protein 54 chr2 GO:0010639 Not Cancer Driver No 63 0.176 98 17 0.173 0
TRIOBP_ENST00000644935 TRIOBP Q9H2D6 TRIO and F-actin-binding protein chr22 GO:0010639 Not Cancer Driver No 386 0.163 2196 370 0.168 1
TRIP13 TRIP13 Q15645 Pachytene checkpoint protein 2 homolog chr5 GO:0010639 Not Cancer Driver No 62 0.144 30 6 0.2 1
TSC2 TSC2 P49815 Tuberin chr16 GO:0010639 Census, Compendium Yes 192 0.106 563 50 0.089 53
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0010639 Not Cancer Driver No 5 0.03 1 0 0.0 0
TTBK2 TTBK2 Q6IQ55 Tau-tubulin kinase 2 chr15 GO:0010639 Not Cancer Driver No 151 0.121 848 107 0.126 0
TUBB4A TUBB4A P04350 Tubulin beta-4A chain chr19 GO:0010639 Not Cancer Driver No 91 0.205 61 16 0.262 2
TWF1_ENST00000395510 TWF1 Q12792 Twinfilin-1 chr12 GO:0010639 Not Cancer Driver No 50 0.143 52 3 0.058 0
TWF2 TWF2 Q6IBS0 Twinfilin-2 chr3 GO:0010639 Not Cancer Driver No 34 0.097 59 8 0.136 0
USP30 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 GO:0010639 Not Cancer Driver No 76 0.147 136 26 0.191 0
VAT1 VAT1 Q99536 Synaptic vesicle membrane protein VAT-1 homolog chr17 GO:0010639 Not Cancer Driver No 39 0.099 83 10 0.12 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0010639 Not Cancer Driver No 124 0.15 222 38 0.171 0
VILL_ENST00000383759 VILL O15195 Villin-like protein chr3 GO:0010639 Not Cancer Driver No 100 0.117 222 28 0.126 0
WAPL_ENST00000618527 WAPL Q7Z5K2 Wings apart-like protein homolog chr10 GO:0010639 Not Cancer Driver No 140 0.118 621 68 0.11 0
WAS WAS P42768 Wiskott-Aldrich syndrome protein chrX GO:0010639 Census, Compendium Yes 75 0.149 400 55 0.138 30
WASF2 WASF2 Q9Y6W5 Wiskott-Aldrich syndrome protein family member 2 chr1 GO:0010639 Not Cancer Driver No 61 0.122 400 43 0.107 0
WDR63 DNAI3 Q8IWG1 Dynein axonemal intermediate chain 3 chr1 GO:0010639 Not Cancer Driver No 129 0.145 210 31 0.148 0
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0010639 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRN1 XRN1 Q8IZH2 5'-3' exoribonuclease 1 chr3 GO:0010639 Not Cancer Driver No 213 0.125 577 65 0.113 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0010639 Not Cancer Driver No 51 0.101 489 49 0.1 0