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Total number of protein in "GO:0010507" GO term:  74

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0010507 Not Cancer Driver No 130 0.279 40 8 0.2 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0010507 Census, Compendium Yes 108 0.225 158 24 0.152 4
ATG7 ATG7 O95352 Ubiquitin-like modifier-activating enzyme ATG7 chr3 GO:0010507 Compendium Yes 77 0.11 53 8 0.151 6
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0010507 Census, Compendium Yes 24 0.1 72 5 0.069 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0010507 Not Cancer Driver No 45 0.1 190 19 0.1 0
BMF_ENST00000561360 BMF Q96LC9 Bcl-2-modifying factor chr15 GO:0010507 Not Cancer Driver No 22 0.12 94 9 0.096 0
CHMP4A_ENST00000609024 CHMP4A Q9BY43 Charged multivesicular body protein 4a chr14 GO:0010507 Not Cancer Driver No 24 0.108 204 23 0.113 0
CHMP4B CHMP4B Q9H444 Charged multivesicular body protein 4b chr20 GO:0010507 Not Cancer Driver No 25 0.112 201 22 0.109 2
CLEC16A CLEC16A Q2KHT3 Protein CLEC16A chr16 GO:0010507 Not Cancer Driver No 149 0.142 374 53 0.142 0
CPTP CPTP Q5TA50 Ceramide-1-phosphate transfer protein chr1 GO:0010507 Not Cancer Driver No 16 0.075 4 0 0.0 0
CTSA_ENST00000372459 CTSA P10619 Lysosomal protective protein chr20 GO:0010507 Not Cancer Driver No 59 0.123 14 1 0.071 12
DAPL1 DAPL1 A0PJW8 Death-associated protein-like 1 chr2 GO:0010507 Not Cancer Driver No 9 0.084 67 5 0.075 0
DAP_ENST00000230895 DAP P51397 Death-associated protein 1 chr5 GO:0010507 Not Cancer Driver No 10 0.098 102 10 0.098 0
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0010507 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0010507 Not Cancer Driver No 26 0.12 54 6 0.111 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0010507 Not Cancer Driver No 229 0.143 1079 153 0.142 2
EIF4G2_ENST00000640650 EIF4G2 P78344 Eukaryotic translation initiation factor 4 gamma 2 chr11 GO:0010507 Not Cancer Driver No 104 0.115 382 43 0.113 0
EIF4G3_ENST00000264211 EIF4G3 O43432 Eukaryotic translation initiation factor 4 gamma 3 chr1 GO:0010507 Not Cancer Driver No 200 0.126 1018 127 0.125 0
FEZ1 FEZ1 Q99689 Fasciculation and elongation protein zeta-1 chr11 GO:0010507 Not Cancer Driver No 66 0.168 277 49 0.177 0
FEZ2_ENST00000405912 FEZ2 Q9UHY8 Fasciculation and elongation protein zeta-2 chr2 GO:0010507 Not Cancer Driver No 37 0.105 245 29 0.118 0
FOXK1 FOXK1 P85037 Forkhead box protein K1 chr7 GO:0010507 Not Cancer Driver No 97 0.132 511 65 0.127 0
FOXK2 FOXK2 Q01167 Forkhead box protein K2 chr17 GO:0010507 Not Cancer Driver No 79 0.12 548 64 0.117 0
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0010507 Not Cancer Driver No 48 0.109 301 34 0.113 18
GOLGA2_ENST00000611957 GOLGA2 Q08379 Golgin subfamily A member 2 chr9 GO:0010507 Not Cancer Driver No 115 0.115 854 96 0.112 0
HERC1 HERC1 Q15751 Probable E3 ubiquitin-protein ligase HERC1 chr15 GO:0010507 Not Cancer Driver No 487 0.1 1344 129 0.096 1
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0010507 Compendium Yes 233 0.32 43 16 0.372 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0010507 Not Cancer Driver No 41 0.085 23 2 0.087 0
IL10 IL10 P22301 Interleukin-10 chr1 GO:0010507 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL10RA IL10RA Q13651 Interleukin-10 receptor subunit alpha chr11 GO:0010507 Not Cancer Driver No 77 0.133 220 26 0.118 7
KDM4A KDM4A O75164 Lysine-specific demethylase 4A chr1 GO:0010507 Not Cancer Driver No 122 0.115 337 44 0.131 0
KIF25_ENST00000443060 KIF25 Q9UIL4 Kinesin-like protein KIF25 chr6 GO:0010507 Not Cancer Driver No 80 0.208 143 37 0.259 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0010507 Not Cancer Driver No 90 0.142 50 8 0.16 0
LEP LEP P41159 Leptin chr7 GO:0010507 Not Cancer Driver No 29 0.174 0 0 0.0 2
LEPR LEPR P48357 Leptin receptor chr1 GO:0010507 Not Cancer Driver No 243 0.209 57 11 0.193 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0010507 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAGEA3 MAGEA3 P43357 Melanoma-associated antigen 3 chrX GO:0010507 Not Cancer Driver No 79 0.252 103 18 0.175 0
MAGEA6 MAGEA6 P43360 Melanoma-associated antigen 6 chrX GO:0010507 Not Cancer Driver No 95 0.303 103 20 0.194 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0010507 Not Cancer Driver No 30 0.086 203 21 0.103 0
MET_ENST00000397752 MET P08581 Hepatocyte growth factor receptor chr7 GO:0010507 Census, Compendium Yes 226 0.163 62 15 0.242 19
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0010507 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTM1 MTM1 Q13496 Myotubularin chrX GO:0010507 Not Cancer Driver No 112 0.186 79 9 0.114 57
MTMR8 MTMR8 Q96EF0 Myotubularin-related protein 8 chrX GO:0010507 Not Cancer Driver No 140 0.199 55 8 0.145 0
MTMR9 MTMR9 Q96QG7 Myotubularin-related protein 9 chr8 GO:0010507 Not Cancer Driver No 60 0.109 45 7 0.156 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0010507 Census, Compendium Yes 379 0.149 296 37 0.125 18
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0010507 Not Cancer Driver No 10 0.122 82 10 0.122 0
PHF23 PHF23 Q9BUL5 PHD finger protein 23 chr17 GO:0010507 Not Cancer Driver No 45 0.112 331 37 0.112 0
PINK1 PINK1 Q9BXM7 Serine/threonine-protein kinase PINK1, mitochondrial chr1 GO:0010507 Not Cancer Driver No 57 0.098 99 13 0.131 23
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0010507 Not Cancer Driver No 141 0.175 364 62 0.17 4
RASIP1 RASIP1 Q5U651 Ras-interacting protein 1 chr19 GO:0010507 Not Cancer Driver No 73 0.076 505 48 0.095 0
RNF41_ENST00000615206 RNF41 Q9H4P4 E3 ubiquitin-protein ligase NRDP1 chr12 GO:0010507 Not Cancer Driver No 44 0.139 33 2 0.061 0
RNF5 RNF5 Q99942 E3 ubiquitin-protein ligase RNF5 chr6 GO:0010507 Not Cancer Driver No 17 0.094 69 3 0.043 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0010507 Not Cancer Driver No 30 0.096 0 0 0.0 0
RUBCN RUBCN Q92622 Run domain Beclin-1-interacting and cysteine-rich domain-containing protein chr3 GO:0010507 Not Cancer Driver No 147 0.151 403 57 0.141 0
SCFD1 SCFD1 Q8WVM8 Sec1 family domain-containing protein 1 chr14 GO:0010507 Not Cancer Driver No 66 0.103 117 12 0.103 0
SIRT2 SIRT2 Q8IXJ6 NAD-dependent protein deacetylase sirtuin-2 chr19 GO:0010507 Not Cancer Driver No 56 0.144 85 17 0.2 0
SMCR8 SMCR8 Q8TEV9 Guanine nucleotide exchange protein SMCR8 chr17 GO:0010507 Not Cancer Driver No 107 0.114 357 38 0.106 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0010507 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNRNP70 SNRNP70 P08621 U1 small nuclear ribonucleoprotein 70 kDa chr19 GO:0010507 Not Cancer Driver No 38 0.087 416 37 0.089 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0010507 Census, Compendium Yes 110 0.143 152 15 0.099 19
TAB2_ENST00000637181 TAB2 Q9NYJ8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 chr6 GO:0010507 Not Cancer Driver No 87 0.126 573 73 0.127 2
TAB3 TAB3 Q8N5C8 TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 chrX GO:0010507 Not Cancer Driver No 130 0.183 654 116 0.177 0
TBC1D14 TBC1D14 Q9P2M4 TBC1 domain family member 14 chr4 GO:0010507 Not Cancer Driver No 80 0.115 311 36 0.116 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0010507 Not Cancer Driver No 44 0.163 39 9 0.231 0
TLK2 TLK2 Q86UE8 Serine/threonine-protein kinase tousled-like 2 chr17 GO:0010507 Not Cancer Driver No 120 0.155 436 58 0.133 5
TMEM39A TMEM39A Q9NV64 Transmembrane protein 39A chr3 GO:0010507 Not Cancer Driver No 53 0.109 14 1 0.071 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0010507 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0010507 Not Cancer Driver No 43 0.187 27 2 0.074 1
TSC2 TSC2 P49815 Tuberin chr16 GO:0010507 Census, Compendium Yes 192 0.106 563 50 0.089 53
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0010507 Not Cancer Driver No 5 0.03 1 0 0.0 0
UBQLN4 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 GO:0010507 Not Cancer Driver No 70 0.116 561 67 0.119 1
USP30 USP30 Q70CQ3 Ubiquitin carboxyl-terminal hydrolase 30 chr12 GO:0010507 Not Cancer Driver No 76 0.147 136 26 0.191 0
WASHC1 WASHC1 A8K0Z3 WASH complex subunit 1 chr9 GO:0010507 Not Cancer Driver No 6 0.013 336 6 0.018 0
WDR6_ENST00000608424 WDR6 Q9NNW5 WD repeat-containing protein 6 chr3 GO:0010507 Not Cancer Driver No 166 0.148 105 13 0.124 0
ZKSCAN3_ENST00000252211 ZKSCAN3 Q9BRR0 Zinc finger protein with KRAB and SCAN domains 3 chr6 GO:0010507 Not Cancer Driver No 70 0.13 267 30 0.112 0