Total number of protein in "GO:0010506" GO term: 174
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0010506 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| ABL2 | ABL2 | P42684 | Tyrosine-protein kinase ABL2 | chr1 | GO:0010506 | Census, Compendium | Yes | 171 | 0.145 | 641 | 70 | 0.109 | 0 |
| ACER2 | ACER2 | Q5QJU3 | Alkaline ceramidase 2 | chr9 | GO:0010506 | Not Cancer Driver | No | 27 | 0.098 | 0 | 0 | 0.0 | 0 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:0010506 | Not Cancer Driver | No | 52 | 0.126 | 35 | 4 | 0.114 | 0 |
| AMBRA1_ENST00000458649 | AMBRA1 | Q9C0C7 | Activating molecule in BECN1-regulated autophagy protein 1 | chr11 | GO:0010506 | Not Cancer Driver | No | 173 | 0.133 | 788 | 103 | 0.131 | 0 |
| ATG2A | ATG2A | Q2TAZ0 | Autophagy-related protein 2 homolog A | chr11 | GO:0010506 | Not Cancer Driver | No | 228 | 0.118 | 887 | 124 | 0.14 | 0 |
| ATG7 | ATG7 | O95352 | Ubiquitin-like modifier-activating enzyme ATG7 | chr3 | GO:0010506 | Compendium | Yes | 77 | 0.11 | 53 | 8 | 0.151 | 6 |
| ATM_ENST00000452508 | ATM | Q13315 | Serine-protein kinase ATM | chr11 | GO:0010506 | Census, Compendium | Yes | 469 | 0.153 | 225 | 39 | 0.173 | 41 |
| ATP13A2 | ATP13A2 | Q9NQ11 | Polyamine-transporting ATPase 13A2 | chr1 | GO:0010506 | Not Cancer Driver | No | 152 | 0.129 | 121 | 10 | 0.083 | 9 |
| BAG3 | BAG3 | O95817 | BAG family molecular chaperone regulator 3 | chr10 | GO:0010506 | Not Cancer Driver | No | 57 | 0.099 | 571 | 57 | 0.1 | 7 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0010506 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BECN1_ENST00000590099 | BECN1 | Q14457 | Beclin-1 | chr17 | GO:0010506 | Not Cancer Driver | No | 45 | 0.1 | 190 | 19 | 0.1 | 0 |
| BNIP3L | BNIP3L | O60238 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like | chr8 | GO:0010506 | Not Cancer Driver | No | 16 | 0.073 | 175 | 14 | 0.08 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0010506 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| C9orf72 | C9orf72 | Q96LT7 | Guanine nucleotide exchange factor C9orf72 | chr9 | GO:0010506 | Not Cancer Driver | No | 64 | 0.133 | 11 | 0 | 0.0 | 0 |
| CALCOCO2_ENST00000258947 | CALCOCO2 | Q13137 | Calcium-binding and coiled-coil domain-containing protein 2 | chr17 | GO:0010506 | Not Cancer Driver | No | 42 | 0.094 | 212 | 19 | 0.09 | 0 |
| CAMKK2 | CAMKK2 | Q96RR4 | Calcium/calmodulin-dependent protein kinase kinase 2 | chr12 | GO:0010506 | Not Cancer Driver | No | 65 | 0.111 | 281 | 35 | 0.125 | 0 |
| CERS1_ENST00000623882 | CERS1 | P27544 | Ceramide synthase 1 | chr19 | GO:0010506 | Not Cancer Driver | No | 29 | 0.083 | 19 | 0 | 0.0 | 1 |
| CHMP4A_ENST00000609024 | CHMP4A | Q9BY43 | Charged multivesicular body protein 4a | chr14 | GO:0010506 | Not Cancer Driver | No | 24 | 0.108 | 204 | 23 | 0.113 | 0 |
| CHMP4B | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | GO:0010506 | Not Cancer Driver | No | 25 | 0.112 | 201 | 22 | 0.109 | 2 |
| CISD1 | CISD1 | Q9NZ45 | CDGSH iron-sulfur domain-containing protein 1 | chr10 | GO:0010506 | Not Cancer Driver | No | 6 | 0.056 | 18 | 0 | 0.0 | 0 |
| CISD2 | CISD2 | Q8N5K1 | CDGSH iron-sulfur domain-containing protein 2 | chr4 | GO:0010506 | Not Cancer Driver | No | 11 | 0.081 | 7 | 0 | 0.0 | 0 |
| CLEC16A | CLEC16A | Q2KHT3 | Protein CLEC16A | chr16 | GO:0010506 | Not Cancer Driver | No | 149 | 0.142 | 374 | 53 | 0.142 | 0 |
| CRYBA1 | CRYBA1 | P05813 | Beta-crystallin A3 | chr17 | GO:0010506 | Not Cancer Driver | No | 29 | 0.135 | 52 | 11 | 0.212 | 0 |
| CSNK2A2 | CSNK2A2 | P19784 | Casein kinase II subunit alpha' | chr16 | GO:0010506 | Not Cancer Driver | No | 43 | 0.123 | 13 | 1 | 0.077 | 0 |
| CTSA_ENST00000372459 | CTSA | P10619 | Lysosomal protective protein | chr20 | GO:0010506 | Not Cancer Driver | No | 59 | 0.123 | 14 | 1 | 0.071 | 12 |
| CTTN_ENST00000301843 | CTTN | Q14247 | Src substrate cortactin | chr11 | GO:0010506 | Not Cancer Driver | No | 78 | 0.142 | 465 | 56 | 0.12 | 0 |
| DAPK1_ENST00000622514 | DAPK1 | P53355 | Death-associated protein kinase 1 | chr9 | GO:0010506 | Not Cancer Driver | No | 193 | 0.135 | 114 | 11 | 0.096 | 0 |
| DAPK2 | DAPK2 | Q9UIK4 | Death-associated protein kinase 2 | chr15 | GO:0010506 | Not Cancer Driver | No | 55 | 0.149 | 53 | 9 | 0.17 | 0 |
| DAPK3_ENST00000301264 | DAPK3 | O43293 | Death-associated protein kinase 3 | chr19 | GO:0010506 | Not Cancer Driver | No | 56 | 0.123 | 82 | 7 | 0.085 | 0 |
| DCAF12 | DCAF12 | Q5T6F0 | DDB1- and CUL4-associated factor 12 | chr9 | GO:0010506 | Not Cancer Driver | No | 59 | 0.13 | 70 | 7 | 0.1 | 0 |
| DCN | DCN | P07585 | Decorin | chr12 | GO:0010506 | Not Cancer Driver | No | 96 | 0.267 | 81 | 26 | 0.321 | 0 |
| DDIT3_ENST00000623876 | DDIT3 | P35638 | DNA damage-inducible transcript 3 protein | chr12 | GO:0010506 | Census | Yes | 29 | 0.172 | 160 | 27 | 0.169 | 0 |
| DEPP1 | DEPP1 | Q9NTK1 | Protein DEPP1 | chr10 | GO:0010506 | Not Cancer Driver | No | 33 | 0.156 | 199 | 33 | 0.166 | 0 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | GO:0010506 | Not Cancer Driver | No | 67 | 0.091 | 212 | 23 | 0.108 | 7 |
| DRAM1 | DRAM1 | Q8N682 | DNA damage-regulated autophagy modulator protein 1 | chr12 | GO:0010506 | Not Cancer Driver | No | 25 | 0.105 | 0 | 0 | 0.0 | 0 |
| DRAM2 | DRAM2 | Q6UX65 | DNA damage-regulated autophagy modulator protein 2 | chr1 | GO:0010506 | Not Cancer Driver | No | 26 | 0.098 | 0 | 0 | 0.0 | 3 |
| EEF1A1 | EEF1A1 | P68104 | Elongation factor 1-alpha 1 | chr6 | GO:0010506 | Not Cancer Driver | No | 109 | 0.236 | 100 | 14 | 0.14 | 0 |
| EEF1A2 | EEF1A2 | Q05639 | Elongation factor 1-alpha 2 | chr20 | GO:0010506 | Not Cancer Driver | No | 74 | 0.16 | 121 | 17 | 0.14 | 3 |
| EHMT2_ENST00000375537 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | GO:0010506 | Not Cancer Driver | No | 142 | 0.117 | 585 | 71 | 0.121 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0010506 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| ERCC4 | ERCC4 | Q92889 | DNA repair endonuclease XPF | chr16 | GO:0010506 | Census | Yes | 120 | 0.131 | 225 | 27 | 0.12 | 15 |
| FBXL2 | FBXL2 | Q9UKC9 | F-box/LRR-repeat protein 2 | chr3 | GO:0010506 | Not Cancer Driver | No | 48 | 0.113 | 0 | 0 | 0.0 | 0 |
| FBXO7 | FBXO7 | Q9Y3I1 | F-box only protein 7 | chr22 | GO:0010506 | Not Cancer Driver | No | 75 | 0.144 | 243 | 38 | 0.156 | 1 |
| FBXW7_ENST00000603841 | FBXW7 | Q969H0 | F-box/WD repeat-containing protein 7 | chr4 | GO:0010506 | Census, Compendium | Yes | 322 | 0.455 | 230 | 38 | 0.165 | 0 |
| FEZ1 | FEZ1 | Q99689 | Fasciculation and elongation protein zeta-1 | chr11 | GO:0010506 | Not Cancer Driver | No | 66 | 0.168 | 277 | 49 | 0.177 | 0 |
| FEZ2_ENST00000405912 | FEZ2 | Q9UHY8 | Fasciculation and elongation protein zeta-2 | chr2 | GO:0010506 | Not Cancer Driver | No | 37 | 0.105 | 245 | 29 | 0.118 | 0 |
| FYCO1 | FYCO1 | Q9BQS8 | FYVE and coiled-coil domain-containing protein 1 | chr3 | GO:0010506 | Not Cancer Driver | No | 181 | 0.122 | 892 | 106 | 0.119 | 1 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0010506 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| GFAP_ENST00000588735 | GFAP | P14136 | Glial fibrillary acidic protein | chr17 | GO:0010506 | Not Cancer Driver | No | 65 | 0.15 | 288 | 42 | 0.146 | 62 |
| GNAI3 | GNAI3 | P08754 | Guanine nucleotide-binding protein G(i) subunit alpha-3 | chr1 | GO:0010506 | Not Cancer Driver | No | 42 | 0.119 | 11 | 0 | 0.0 | 1 |
| GPR137B | GPR137B | O60478 | Integral membrane protein GPR137B | chr1 | GO:0010506 | Not Cancer Driver | No | 49 | 0.123 | 47 | 1 | 0.021 | 0 |
| GPR137_ENST00000313074 | GPR137 | Q96N19 | Integral membrane protein GPR137 | chr11 | GO:0010506 | Not Cancer Driver | No | 66 | 0.158 | 41 | 11 | 0.268 | 0 |
| GPSM1 | GPSM1 | Q86YR5 | G-protein-signaling modulator 1 | chr9 | GO:0010506 | Not Cancer Driver | No | 68 | 0.101 | 344 | 35 | 0.102 | 0 |
| GSK3A | GSK3A | P49840 | Glycogen synthase kinase-3 alpha | chr19 | GO:0010506 | Not Cancer Driver | No | 55 | 0.114 | 180 | 8 | 0.044 | 0 |
| HAX1 | HAX1 | O00165 | HCLS1-associated protein X-1 | chr1 | GO:0010506 | Not Cancer Driver | No | 44 | 0.158 | 219 | 32 | 0.146 | 2 |
| HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0010506 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
| HIF1A_ENST00000337138 | HIF1A | Q16665 | Hypoxia-inducible factor 1-alpha | chr14 | GO:0010506 | Census | Yes | 118 | 0.143 | 435 | 51 | 0.117 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0010506 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0010506 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
| HSPB8 | HSPB8 | Q9UJY1 | Heat shock protein beta-8 | chr12 | GO:0010506 | Not Cancer Driver | No | 40 | 0.204 | 130 | 31 | 0.238 | 5 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0010506 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
| HTT | HTT | P42858 | Huntingtin | chr4 | GO:0010506 | Not Cancer Driver | No | 336 | 0.107 | 666 | 69 | 0.104 | 2 |
| IFI16_ENST00000295809 | IFI16 | Q16666 | Gamma-interferon-inducible protein 16 | chr1 | GO:0010506 | Not Cancer Driver | No | 155 | 0.197 | 419 | 90 | 0.215 | 0 |
| IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | GO:0010506 | Not Cancer Driver | No | 6 | 0.014 | 301 | 6 | 0.02 | 22 |
| IL4 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0010506 | Not Cancer Driver | No | 18 | 0.118 | 0 | 0 | 0.0 | 0 |
| IRGM | IRGM | A1A4Y4 | Immunity-related GTPase family M protein | chr5 | GO:0010506 | Not Cancer Driver | No | 9 | 0.05 | 45 | 1 | 0.022 | 0 |
| ITPR1_ENST00000354582 | ITPR1 | Q14643 | Inositol 1,4,5-trisphosphate receptor type 1 | chr3 | GO:0010506 | Not Cancer Driver | No | 390 | 0.141 | 581 | 76 | 0.131 | 6 |
| KAT8_ENST00000219797 | KAT8 | Q9H7Z6 | Histone acetyltransferase KAT8 | chr16 | GO:0010506 | Not Cancer Driver | No | 66 | 0.144 | 156 | 20 | 0.128 | 4 |
| KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0010506 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
| KEAP1_ENST00000393623 | KEAP1 | Q14145 | Kelch-like ECH-associated protein 1 | chr19 | GO:0010506 | Census, Compendium | Yes | 237 | 0.38 | 57 | 12 | 0.211 | 0 |
| KIAA1324 | ELAPOR1 | Q6UXG2 | Endosome/lysosome-associated apoptosis and autophagy regulator 1 | chr1 | GO:0010506 | Not Cancer Driver | No | 94 | 0.093 | 56 | 5 | 0.089 | 0 |
| LACRT | LACRT | Q9GZZ8 | Extracellular glycoprotein lacritin | chr12 | GO:0010506 | Not Cancer Driver | No | 38 | 0.275 | 90 | 27 | 0.3 | 0 |
| LAMP3 | LAMP3 | Q9UQV4 | Lysosome-associated membrane glycoprotein 3 | chr3 | GO:0010506 | Not Cancer Driver | No | 67 | 0.161 | 222 | 38 | 0.171 | 0 |
| LRRK2 | LRRK2 | Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 | chr12 | GO:0010506 | Not Cancer Driver | No | 519 | 0.205 | 90 | 17 | 0.189 | 23 |
| LRSAM1_ENST00000373322 | LRSAM1 | Q6UWE0 | E3 ubiquitin-protein ligase LRSAM1 | chr9 | GO:0010506 | Not Cancer Driver | No | 86 | 0.119 | 240 | 30 | 0.125 | 1 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0010506 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| MAPK15 | MAPK15 | Q8TD08 | Mitogen-activated protein kinase 15 | chr8 | GO:0010506 | Not Cancer Driver | No | 81 | 0.149 | 235 | 37 | 0.157 | 0 |
| MAPK3 | MAPK3 | P27361 | Mitogen-activated protein kinase 3 | chr16 | GO:0010506 | Not Cancer Driver | No | 38 | 0.1 | 49 | 5 | 0.102 | 0 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0010506 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
| MFSD8_ENST00000296468 | MFSD8 | Q8NHS3 | Major facilitator superfamily domain-containing protein 8 | chr4 | GO:0010506 | Not Cancer Driver | No | 69 | 0.133 | 16 | 3 | 0.188 | 16 |
| MOAP1_ENST00000298894 | MOAP1 | Q96BY2 | Modulator of apoptosis 1 | chr14 | GO:0010506 | Not Cancer Driver | No | 48 | 0.137 | 47 | 8 | 0.17 | 0 |
| MTCL1_ENST00000306329 | MTCL1 | Q9Y4B5 | Microtubule cross-linking factor 1 | chr18 | GO:0010506 | Not Cancer Driver | No | 267 | 0.14 | 1681 | 232 | 0.138 | 0 |
| MTM1 | MTM1 | Q13496 | Myotubularin | chrX | GO:0010506 | Not Cancer Driver | No | 112 | 0.186 | 79 | 9 | 0.114 | 57 |
| MTMR3 | MTMR3 | Q13615 | Myotubularin-related protein 3 | chr22 | GO:0010506 | Not Cancer Driver | No | 130 | 0.109 | 501 | 66 | 0.132 | 0 |
| MTMR4 | MTMR4 | Q9NYA4 | Myotubularin-related protein 4 | chr17 | GO:0010506 | Not Cancer Driver | No | 147 | 0.123 | 474 | 59 | 0.124 | 0 |
| NLRP6 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0010506 | Not Cancer Driver | No | 106 | 0.119 | 203 | 28 | 0.138 | 0 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0010506 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0010506 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0010506 | Not Cancer Driver | No | 10 | 0.122 | 82 | 10 | 0.122 | 0 |
| OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | GO:0010506 | Not Cancer Driver | No | 58 | 0.101 | 470 | 51 | 0.109 | 6 |
| OSBPL7_ENST00000392507 | OSBPL7 | Q9BZF2 | Oxysterol-binding protein-related protein 7 | chr17 | GO:0010506 | Not Cancer Driver | No | 99 | 0.118 | 395 | 44 | 0.111 | 0 |
| PAFAH1B2 | PAFAH1B2 | P68402 | Platelet-activating factor acetylhydrolase IB subunit alpha2 | chr11 | GO:0010506 | Census | Yes | 25 | 0.109 | 43 | 1 | 0.023 | 0 |
| PARK7_ENST00000377488 | PARK7 | Q99497 | Parkinson disease protein 7 | chr1 | GO:0010506 | Not Cancer Driver | No | 11 | 0.058 | 30 | 0 | 0.0 | 5 |
| PARL | PARL | Q9H300 | Presenilins-associated rhomboid-like protein, mitochondrial | chr3 | GO:0010506 | Not Cancer Driver | No | 49 | 0.129 | 28 | 5 | 0.179 | 0 |
| PHF23 | PHF23 | Q9BUL5 | PHD finger protein 23 | chr17 | GO:0010506 | Not Cancer Driver | No | 45 | 0.112 | 331 | 37 | 0.112 | 0 |
| PIK3C3 | PIK3C3 | Q8NEB9 | Phosphatidylinositol 3-kinase catalytic subunit type 3 | chr18 | GO:0010506 | Not Cancer Driver | No | 127 | 0.143 | 191 | 34 | 0.178 | 0 |
| PIK3R2_ENST00000617130 | PIK3R2 | O00459 | Phosphatidylinositol 3-kinase regulatory subunit beta | chr19 | GO:0010506 | Not Cancer Driver | No | 96 | 0.132 | 418 | 47 | 0.112 | 3 |
| PIK3R4 | PIK3R4 | Q99570 | Phosphoinositide 3-kinase regulatory subunit 4 | chr3 | GO:0010506 | Not Cancer Driver | No | 193 | 0.142 | 315 | 45 | 0.143 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0010506 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PIP4K2A | PIP4K2A | P48426 | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | chr10 | GO:0010506 | Not Cancer Driver | No | 56 | 0.138 | 123 | 15 | 0.122 | 0 |
| PIP4K2C_ENST00000540759 | PIP4K2C | Q8TBX8 | Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma | chr12 | GO:0010506 | Not Cancer Driver | No | 62 | 0.147 | 111 | 23 | 0.207 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0010506 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PRKAA2 | PRKAA2 | P54646 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 | chr1 | GO:0010506 | Not Cancer Driver | No | 128 | 0.232 | 98 | 26 | 0.265 | 0 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0010506 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| PSAP | PSAP | P07602 | Prosaposin | chr10 | GO:0010506 | Not Cancer Driver | No | 59 | 0.113 | 28 | 2 | 0.071 | 8 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0010506 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RAB39B | RAB39B | Q96DA2 | Ras-related protein Rab-39B | chrX | GO:0010506 | Not Cancer Driver | No | 45 | 0.211 | 0 | 0 | 0.0 | 2 |
| RAB3GAP1_ENST00000264158 | RAB3GAP1 | Q15042 | Rab3 GTPase-activating protein catalytic subunit | chr2 | GO:0010506 | Not Cancer Driver | No | 123 | 0.125 | 294 | 32 | 0.109 | 2 |
| RAB3GAP2 | RAB3GAP2 | Q9H2M9 | Rab3 GTPase-activating protein non-catalytic subunit | chr1 | GO:0010506 | Not Cancer Driver | No | 168 | 0.121 | 143 | 17 | 0.119 | 2 |
| RAB8A | RAB8A | P61006 | Ras-related protein Rab-8A | chr19 | GO:0010506 | Not Cancer Driver | No | 37 | 0.179 | 26 | 3 | 0.115 | 0 |
| RALB | RALB | P11234 | Ras-related protein Ral-B | chr2 | GO:0010506 | Not Cancer Driver | No | 36 | 0.175 | 35 | 5 | 0.143 | 0 |
| RIPK2 | RIPK2 | O43353 | Receptor-interacting serine/threonine-protein kinase 2 | chr8 | GO:0010506 | Not Cancer Driver | No | 63 | 0.117 | 143 | 20 | 0.14 | 0 |
| RMC1 | RMC1 | Q96DM3 | Regulator of MON1-CCZ1 complex | chr18 | GO:0010506 | Not Cancer Driver | No | 70 | 0.107 | 12 | 0 | 0.0 | 0 |
| RNF31 | RNF31 | Q96EP0 | E3 ubiquitin-protein ligase RNF31 | chr14 | GO:0010506 | Not Cancer Driver | No | 142 | 0.132 | 319 | 45 | 0.141 | 0 |
| RNF41_ENST00000615206 | RNF41 | Q9H4P4 | E3 ubiquitin-protein ligase NRDP1 | chr12 | GO:0010506 | Not Cancer Driver | No | 44 | 0.139 | 33 | 2 | 0.061 | 0 |
| ROCK1 | ROCK1 | Q13464 | Rho-associated protein kinase 1 | chr18 | GO:0010506 | Not Cancer Driver | No | 184 | 0.136 | 780 | 103 | 0.132 | 0 |
| RPTOR | RPTOR | Q8N122 | Regulatory-associated protein of mTOR | chr17 | GO:0010506 | Not Cancer Driver | No | 176 | 0.132 | 241 | 21 | 0.087 | 0 |
| RRAGA | RRAGA | Q7L523 | Ras-related GTP-binding protein A | chr9 | GO:0010506 | Not Cancer Driver | No | 30 | 0.096 | 0 | 0 | 0.0 | 0 |
| RRAGB | RRAGB | Q5VZM2 | Ras-related GTP-binding protein B | chrX | GO:0010506 | Not Cancer Driver | No | 67 | 0.179 | 37 | 5 | 0.135 | 0 |
| RRAGC | RRAGC | Q9HB90 | Ras-related GTP-binding protein C | chr1 | GO:0010506 | Compendium | Yes | 29 | 0.073 | 61 | 1 | 0.016 | 0 |
| RRAGD | RRAGD | Q9NQL2 | Ras-related GTP-binding protein D | chr6 | GO:0010506 | Not Cancer Driver | No | 42 | 0.105 | 83 | 5 | 0.06 | 0 |
| RUBCN | RUBCN | Q92622 | Run domain Beclin-1-interacting and cysteine-rich domain-containing protein | chr3 | GO:0010506 | Not Cancer Driver | No | 147 | 0.151 | 403 | 57 | 0.141 | 0 |
| RUFY4_ENST00000344321 | RUFY4 | Q6ZNE9 | RUN and FYVE domain-containing protein 4 | chr2 | GO:0010506 | Not Cancer Driver | No | 77 | 0.135 | 307 | 51 | 0.166 | 0 |
| SCFD1 | SCFD1 | Q8WVM8 | Sec1 family domain-containing protein 1 | chr14 | GO:0010506 | Not Cancer Driver | No | 66 | 0.103 | 117 | 12 | 0.103 | 0 |
| SCOC | SCOC | Q9UIL1 | Short coiled-coil protein | chr4 | GO:0010506 | Not Cancer Driver | No | 13 | 0.082 | 82 | 8 | 0.098 | 0 |
| SESN1_ENST00000356644 | SESN1 | Q9Y6P5 | Sestrin-1 | chr6 | GO:0010506 | Not Cancer Driver | No | 45 | 0.091 | 48 | 4 | 0.083 | 0 |
| SESN2 | SESN2 | P58004 | Sestrin-2 | chr1 | GO:0010506 | Not Cancer Driver | No | 74 | 0.154 | 147 | 26 | 0.177 | 0 |
| SESN3 | SESN3 | P58005 | Sestrin-3 | chr11 | GO:0010506 | Not Cancer Driver | No | 84 | 0.171 | 44 | 4 | 0.091 | 0 |
| SH3GLB1_ENST00000370558 | SH3GLB1 | Q9Y371 | Endophilin-B1 | chr1 | GO:0010506 | Not Cancer Driver | No | 41 | 0.112 | 82 | 10 | 0.122 | 0 |
| SIRT1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | chr10 | GO:0010506 | Not Cancer Driver | No | 70 | 0.094 | 435 | 31 | 0.071 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | GO:0010506 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 9 |
| SLC25A5 | SLC25A5 | P05141 | ADP/ATP translocase 2 | chrX | GO:0010506 | Not Cancer Driver | No | 41 | 0.138 | 0 | 0 | 0.0 | 0 |
| SMCR8 | SMCR8 | Q8TEV9 | Guanine nucleotide exchange protein SMCR8 | chr17 | GO:0010506 | Not Cancer Driver | No | 107 | 0.114 | 357 | 38 | 0.106 | 0 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0010506 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| SNRNP70 | SNRNP70 | P08621 | U1 small nuclear ribonucleoprotein 70 kDa | chr19 | GO:0010506 | Not Cancer Driver | No | 38 | 0.087 | 416 | 37 | 0.089 | 0 |
| SNX18 | SNX18 | Q96RF0 | Sorting nexin-18 | chr5 | GO:0010506 | Not Cancer Driver | No | 54 | 0.086 | 236 | 7 | 0.03 | 0 |
| SNX30 | SNX30 | Q5VWJ9 | Sorting nexin-30 | chr9 | GO:0010506 | Not Cancer Driver | No | 36 | 0.082 | 98 | 4 | 0.041 | 0 |
| SNX4 | SNX4 | O95219 | Sorting nexin-4 | chr3 | GO:0010506 | Not Cancer Driver | No | 31 | 0.069 | 101 | 5 | 0.05 | 0 |
| SOGA3 | SOGA3 | Q5TF21 | Protein SOGA3 | chr6 | GO:0010506 | Not Cancer Driver | No | 180 | 0.19 | 792 | 137 | 0.173 | 0 |
| SPTLC1 | SPTLC1 | O15269 | Serine palmitoyltransferase 1 | chr9 | GO:0010506 | Not Cancer Driver | No | 50 | 0.106 | 27 | 5 | 0.185 | 5 |
| SPTLC2 | SPTLC2 | O15270 | Serine palmitoyltransferase 2 | chr14 | GO:0010506 | Not Cancer Driver | No | 72 | 0.128 | 9 | 2 | 0.222 | 5 |
| SREBF1_ENST00000261646 | SREBF1 | P36956 | Sterol regulatory element-binding protein 1 | chr17 | GO:0010506 | Not Cancer Driver | No | 127 | 0.111 | 528 | 64 | 0.121 | 4 |
| SREBF2 | SREBF2 | Q12772 | Sterol regulatory element-binding protein 2 | chr22 | GO:0010506 | Not Cancer Driver | No | 124 | 0.109 | 357 | 43 | 0.12 | 0 |
| SUPT5H | SUPT5H | O00267 | Transcription elongation factor SPT5 | chr19 | GO:0010506 | Not Cancer Driver | No | 165 | 0.152 | 572 | 87 | 0.152 | 0 |
| TBK1 | TBK1 | Q9UHD2 | Serine/threonine-protein kinase TBK1 | chr12 | GO:0010506 | Not Cancer Driver | No | 101 | 0.139 | 42 | 5 | 0.119 | 12 |
| TIGAR | TIGAR | Q9NQ88 | Fructose-2,6-bisphosphatase TIGAR | chr12 | GO:0010506 | Not Cancer Driver | No | 44 | 0.163 | 39 | 9 | 0.231 | 0 |
| TMEM173 | STING1 | Q86WV6 | Stimulator of interferon genes protein | chr5 | GO:0010506 | Not Cancer Driver | No | 46 | 0.121 | 66 | 13 | 0.197 | 3 |
| TMEM39A | TMEM39A | Q9NV64 | Transmembrane protein 39A | chr3 | GO:0010506 | Not Cancer Driver | No | 53 | 0.109 | 14 | 1 | 0.071 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0010506 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TPCN2 | TPCN2 | Q8NHX9 | Two pore channel protein 2 | chr11 | GO:0010506 | Not Cancer Driver | No | 73 | 0.097 | 16 | 0 | 0.0 | 0 |
| TRIB3_ENST00000217233 | TRIB3 | Q96RU7 | Tribbles homolog 3 | chr20 | GO:0010506 | Not Cancer Driver | No | 65 | 0.182 | 114 | 24 | 0.211 | 0 |
| TRIM13_ENST00000378182 | TRIM13 | O60858 | E3 ubiquitin-protein ligase TRIM13 | chr13 | GO:0010506 | Not Cancer Driver | No | 53 | 0.13 | 1 | 0 | 0.0 | 0 |
| TSC1 | TSC1 | Q92574 | Hamartin | chr9 | GO:0010506 | Census, Compendium | Yes | 135 | 0.116 | 732 | 78 | 0.107 | 11 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | GO:0010506 | Census, Compendium | Yes | 192 | 0.106 | 563 | 50 | 0.089 | 53 |
| TSPO_ENST00000329563 | TSPO | P30536 | Translocator protein | chr22 | GO:0010506 | Not Cancer Driver | No | 5 | 0.03 | 1 | 0 | 0.0 | 0 |
| UBQLN4 | UBQLN4 | Q9NRR5 | Ubiquilin-4 | chr1 | GO:0010506 | Not Cancer Driver | No | 70 | 0.116 | 561 | 67 | 0.119 | 1 |
| ULK1 | ULK1 | O75385 | Serine/threonine-protein kinase ULK1 | chr12 | GO:0010506 | Not Cancer Driver | No | 142 | 0.135 | 588 | 77 | 0.131 | 0 |
| USP10_ENST00000219473 | USP10 | Q14694 | Ubiquitin carboxyl-terminal hydrolase 10 | chr16 | GO:0010506 | Not Cancer Driver | No | 92 | 0.115 | 425 | 49 | 0.115 | 0 |
| USP13 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | GO:0010506 | Not Cancer Driver | No | 121 | 0.14 | 224 | 42 | 0.188 | 0 |
| USP30 | USP30 | Q70CQ3 | Ubiquitin carboxyl-terminal hydrolase 30 | chr12 | GO:0010506 | Not Cancer Driver | No | 76 | 0.147 | 136 | 26 | 0.191 | 0 |
| USP33_ENST00000357428 | USP33 | Q8TEY7 | Ubiquitin carboxyl-terminal hydrolase 33 | chr1 | GO:0010506 | Not Cancer Driver | No | 138 | 0.146 | 256 | 48 | 0.188 | 0 |
| USP36_ENST00000312010 | USP36 | Q9P275 | Ubiquitin carboxyl-terminal hydrolase 36 | chr17 | GO:0010506 | Not Cancer Driver | No | 151 | 0.134 | 718 | 91 | 0.127 | 0 |
| UVRAG | UVRAG | Q9P2Y5 | UV radiation resistance-associated gene protein | chr11 | GO:0010506 | Not Cancer Driver | No | 89 | 0.127 | 243 | 28 | 0.115 | 0 |
| VDAC1_ENST00000395047 | VDAC1 | P21796 | Voltage-dependent anion-selective channel protein 1 | chr5 | GO:0010506 | Not Cancer Driver | No | 38 | 0.134 | 36 | 4 | 0.111 | 0 |
| VPS13C_ENST00000261517 | VPS13C | Q709C8 | Intermembrane lipid transfer protein VPS13C | chr15 | GO:0010506 | Not Cancer Driver | No | 446 | 0.119 | 433 | 51 | 0.118 | 1 |
| VPS13D | VPS13D | Q5THJ4 | Intermembrane lipid transfer protein VPS13D | chr1 | GO:0010506 | Not Cancer Driver | No | 501 | 0.114 | 973 | 118 | 0.121 | 8 |
| VPS29_ENST00000549578 | VPS29 | Q9UBQ0 | Vacuolar protein sorting-associated protein 29 | chr12 | GO:0010506 | Not Cancer Driver | No | 24 | 0.132 | 0 | 0 | 0.0 | 0 |
| WAC | WAC | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | chr10 | GO:0010506 | Not Cancer Driver | No | 106 | 0.164 | 571 | 95 | 0.166 | 0 |
| WDR24 | WDR24 | Q96S15 | GATOR complex protein WDR24 | chr16 | GO:0010506 | Not Cancer Driver | No | 87 | 0.11 | 150 | 17 | 0.113 | 0 |
| WDR41 | WDR41 | Q9HAD4 | WD repeat-containing protein 41 | chr5 | GO:0010506 | Not Cancer Driver | No | 48 | 0.105 | 23 | 2 | 0.087 | 0 |
| WDR45_ENST00000634944 | WDR45 | Q9Y484 | WD repeat domain phosphoinositide-interacting protein 4 | chrX | GO:0010506 | Compendium | Yes | 62 | 0.172 | 10 | 1 | 0.1 | 0 |
| WIPI1 | WIPI1 | Q5MNZ9 | WD repeat domain phosphoinositide-interacting protein 1 | chr17 | GO:0010506 | Not Cancer Driver | No | 45 | 0.101 | 113 | 9 | 0.08 | 0 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0010506 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |