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Total number of protein in "GO:0010467" GO term:  96

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADAMTS3 ADAMTS3 O15072 A disintegrin and metalloproteinase with thrombospondin motifs 3 chr4 GO:0010467 Not Cancer Driver No 253 0.21 295 78 0.264 2
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0010467 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0010467 Not Cancer Driver No 39 0.16 92 21 0.228 1
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0010467 Census, Compendium Yes 108 0.225 158 24 0.152 4
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0010467 Not Cancer Driver No 63 0.127 96 10 0.104 1
APOE APOE P02649 Apolipoprotein E chr19 GO:0010467 Not Cancer Driver No 25 0.079 124 6 0.048 12
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0010467 Census, Compendium Yes 34 0.286 5 1 0.2 2
BLOC1S5 BLOC1S5 Q8TDH9 Biogenesis of lysosome-related organelles complex 1 subunit 5 chr6 GO:0010467 Not Cancer Driver No 15 0.08 153 13 0.085 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0010467 Not Cancer Driver No 12 0.07 111 11 0.099 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0010467 Not Cancer Driver No 73 0.121 95 12 0.126 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0010467 Census Yes 402 0.274 1182 337 0.285 103
CRB1 CRB1 P82279 Protein crumbs homolog 1 chr1 GO:0010467 Not Cancer Driver No 464 0.33 28 5 0.179 74
DOT1L DOT1L Q8TEK3 Histone-lysine N-methyltransferase, H3 lysine-79 specific chr19 GO:0010467 Compendium Yes 178 0.116 988 118 0.119 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0010467 Not Cancer Driver No 49 0.14 210 25 0.119 0
EDA EDA Q92838 Ectodysplasin-A chrX GO:0010467 Not Cancer Driver No 73 0.187 243 43 0.177 71
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0010467 Not Cancer Driver No 62 0.145 21 6 0.286 2
EDNRB_ENST00000334286 EDNRB P24530 Endothelin receptor type B chr13 GO:0010467 Not Cancer Driver No 112 0.253 56 19 0.339 6
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0010467 Compendium Yes 90 0.189 352 59 0.168 11
ELAC2 ELAC2 Q9BQ52 Zinc phosphodiesterase ELAC protein 2 chr17 GO:0010467 Not Cancer Driver No 86 0.104 208 30 0.144 10
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0010467 Not Cancer Driver No 51 0.119 327 34 0.104 0
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0010467 Census Yes 107 0.143 58 7 0.121 12
EXT2_ENST00000533608 EXT2 Q93063 Exostosin-2 chr11 GO:0010467 Census, Compendium Yes 93 0.13 12 1 0.083 9
FMN1 FMN1 Q68DA7 Formin-1 chr15 GO:0010467 Not Cancer Driver No 117 0.082 983 67 0.068 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0010467 Not Cancer Driver No 38 0.088 186 16 0.086 10
GAPT GAPT Q8N292 Protein GAPT chr5 GO:0010467 Not Cancer Driver No 41 0.261 83 27 0.325 0
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0010467 Not Cancer Driver No 57 0.096 476 51 0.107 10
GFAP_ENST00000588735 GFAP P14136 Glial fibrillary acidic protein chr17 GO:0010467 Not Cancer Driver No 65 0.15 288 42 0.146 62
GOLPH3 GOLPH3 Q9H4A6 Golgi phosphoprotein 3 chr5 GO:0010467 Not Cancer Driver No 41 0.138 72 1 0.014 0
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 GO:0010467 Not Cancer Driver No 94 0.158 220 38 0.173 0
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0010467 Not Cancer Driver No 143 0.164 24 3 0.125 0
GRM3 GRM3 Q14832 Metabotropic glutamate receptor 3 chr7 GO:0010467 Census Yes 323 0.367 8 3 0.375 0
HELT HELT A6NFD8 Hairy and enhancer of split-related protein HELT chr4 GO:0010467 Not Cancer Driver No 39 0.161 131 21 0.16 0
HESX1 HESX1 Q9UBX0 Homeobox expressed in ES cells 1 chr3 GO:0010467 Not Cancer Driver No 32 0.173 59 9 0.153 6
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0010467 Census Yes 118 0.143 435 51 0.117 0
HLA-DMA HLA-DMA P28067 HLA class II histocompatibility antigen, DM alpha chain chr6 GO:0010467 Not Cancer Driver No 27 0.103 16 2 0.125 0
HLA-DMB HLA-DMB P28068 HLA class II histocompatibility antigen, DM beta chain chr6 GO:0010467 Not Cancer Driver No 41 0.156 41 9 0.22 0
HLA-DOA HLA-DOA P06340 HLA class II histocompatibility antigen, DO alpha chain chr6 GO:0010467 Not Cancer Driver No 39 0.156 7 1 0.143 0
HLA-DOB HLA-DOB P13765 HLA class II histocompatibility antigen, DO beta chain chr6 GO:0010467 Not Cancer Driver No 34 0.125 9 2 0.222 0
HLA-DPA1 HLA-DPA1 P20036 HLA class II histocompatibility antigen, DP alpha 1 chain chr6 GO:0010467 Not Cancer Driver No 37 0.142 30 4 0.133 0
HLA-DPB1 HLA-DPB1 P04440 HLA class II histocompatibility antigen, DP beta 1 chain chr6 GO:0010467 Not Cancer Driver No 38 0.147 39 4 0.103 0
HLA-DQA2 HLA-DQA2 P01906 HLA class II histocompatibility antigen, DQ alpha 2 chain chr6 GO:0010467 Not Cancer Driver No 61 0.239 7 0 0.0 0
HLA-DQB2 HLA-DQB2 P05538 HLA class II histocompatibility antigen, DQ beta 2 chain chr6 GO:0010467 Not Cancer Driver No 55 0.205 38 5 0.132 0
HLA-DRA HLA-DRA P01903 HLA class II histocompatibility antigen, DR alpha chain chr6 GO:0010467 Not Cancer Driver No 52 0.205 12 1 0.083 0
HLA-DRB1 HLA-DRB1 P01911 HLA class II histocompatibility antigen, DRB1 beta chain chr6 GO:0010467 Not Cancer Driver No 48 0.18 12 1 0.083 0
HLA-DRB5 HLA-DRB5 Q30154 HLA class II histocompatibility antigen, DR beta 5 chain chr6 GO:0010467 Not Cancer Driver No 35 0.132 18 2 0.111 0
HOXA3_ENST00000396352 HOXA3 O43365 Homeobox protein Hox-A3 chr7 GO:0010467 Not Cancer Driver No 86 0.194 417 84 0.201 0
HSD17B10 HSD17B10 Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 chrX GO:0010467 Not Cancer Driver No 27 0.103 15 3 0.2 11
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0010467 Not Cancer Driver No 108 0.151 76 13 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0010467 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0010467 Census Yes 24 0.157 6 1 0.167 0
IL6 IL6 P05231 Interleukin-6 chr7 GO:0010467 Not Cancer Driver No 35 0.165 58 7 0.121 0
IL6R IL6R P08887 Interleukin-6 receptor subunit alpha chr1 GO:0010467 Not Cancer Driver No 55 0.118 165 23 0.139 1
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0010467 Census Yes 153 0.146 92 9 0.098 0
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0010467 Not Cancer Driver No 120 0.152 26 4 0.154 3
KBTBD2 KBTBD2 Q8IY47 Kelch repeat and BTB domain-containing protein 2 chr7 GO:0010467 Not Cancer Driver No 72 0.116 25 4 0.16 0
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0010467 Not Cancer Driver No 78 0.115 219 20 0.091 132
KIAA0391 PRORP O15091 Mitochondrial ribonuclease P catalytic subunit chr14 GO:0010467 Not Cancer Driver No 62 0.106 60 12 0.2 0
LAT_ENST00000360872 LAT O43561 Linker for activation of T-cells family member 1 chr16 GO:0010467 Not Cancer Driver No 37 0.141 213 29 0.136 0
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0010467 Not Cancer Driver No 65 0.184 9 0 0.0 0
LRRC19 LRRC19 Q9H756 Leucine-rich repeat-containing protein 19 chr9 GO:0010467 Not Cancer Driver No 37 0.1 30 3 0.1 0
LTB LTB Q06643 Lymphotoxin-beta chr6 GO:0010467 Compendium Yes 33 0.135 91 13 0.143 0
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0010467 Not Cancer Driver No 8 0.03 247 7 0.028 0
MLLT3 MLLT3 P42568 Protein AF-9 chr9 GO:0010467 Census, Compendium Yes 69 0.121 414 58 0.14 0
MPP5 PALS1 Q8N3R9 Protein PALS1 chr14 GO:0010467 Not Cancer Driver No 70 0.104 337 33 0.098 0
MTO1_ENST00000370300 MTO1 Q9Y2Z2 Protein MTO1 homolog, mitochondrial chr6 GO:0010467 Not Cancer Driver No 70 0.098 61 2 0.033 1
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0010467 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOX4 NOX4 Q9NPH5 NADPH oxidase 4 chr11 GO:0010467 Not Cancer Driver No 123 0.213 0 0 0.0 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 GO:0010467 Not Cancer Driver No 155 0.121 24 0 0.0 150
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0010467 Not Cancer Driver No 72 0.171 337 56 0.166 38
PBXIP1 PBXIP1 Q96AQ6 Pre-B-cell leukemia transcription factor-interacting protein 1 chr1 GO:0010467 Not Cancer Driver No 100 0.137 605 86 0.142 0
PLEC PLEC Q15149 Plectin chr8 GO:0010467 Not Cancer Driver No 677 0.145 2130 272 0.128 2
PNPT1 PNPT1 Q8TCS8 Polyribonucleotide nucleotidyltransferase 1, mitochondrial chr2 GO:0010467 Not Cancer Driver No 86 0.11 115 10 0.087 2
PUS1 PUS1 Q9Y606 Pseudouridylate synthase 1 homolog chr12 GO:0010467 Not Cancer Driver No 48 0.112 157 18 0.115 1
PVALB_ENST00000417718 PVALB P20472 Parvalbumin alpha chr22 GO:0010467 Not Cancer Driver No 19 0.173 9 1 0.111 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 GO:0010467 Not Cancer Driver No 40 0.119 203 22 0.108 0
RPUSD4 RPUSD4 Q96CM3 Pseudouridylate synthase RPUSD4, mitochondrial chr11 GO:0010467 Not Cancer Driver No 54 0.143 97 15 0.155 0
RTN2 RTN2 O75298 Reticulon-2 chr19 GO:0010467 Not Cancer Driver No 85 0.156 270 55 0.204 1
SCARB2 SCARB2 Q14108 Lysosome membrane protein 2 chr4 GO:0010467 Not Cancer Driver No 61 0.128 13 3 0.231 1
SCNN1B SCNN1B P51168 Amiloride-sensitive sodium channel subunit beta chr16 GO:0010467 Not Cancer Driver No 90 0.141 62 4 0.065 13
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0010467 Census, Compendium Yes 49 0.173 144 25 0.174 8
SLAMF9 SLAMF9 Q96A28 SLAM family member 9 chr1 GO:0010467 Not Cancer Driver No 67 0.232 28 7 0.25 0
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0010467 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC3A1 SLC3A1 Q07837 Neutral and basic amino acid transport protein rBAT chr2 GO:0010467 Not Cancer Driver No 103 0.15 90 20 0.222 49
SUPV3L1 SUPV3L1 Q8IYB8 ATP-dependent RNA helicase SUPV3L1, mitochondrial chr10 GO:0010467 Not Cancer Driver No 72 0.092 140 12 0.086 0
SVEP1 SVEP1 Q4LDE5 Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 chr9 GO:0010467 Not Cancer Driver No 626 0.175 229 33 0.144 0
TBRG4_ENST00000494076 TBRG4 Q969Z0 FAST kinase domain-containing protein 4 chr7 GO:0010467 Not Cancer Driver No 74 0.117 60 2 0.033 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0010467 Compendium Yes 68 0.082 102 6 0.059 5
TFAP2B TFAP2B Q92481 Transcription factor AP-2-beta chr6 GO:0010467 Not Cancer Driver No 114 0.248 306 75 0.245 6
TNF TNF P01375 Tumor necrosis factor chr6 GO:0010467 Not Cancer Driver No 24 0.103 45 3 0.067 0
TREM1 TREM1 Q9NP99 Triggering receptor expressed on myeloid cells 1 chr6 GO:0010467 Not Cancer Driver No 45 0.192 63 7 0.111 0
TRIT1 TRIT1 Q9H3H1 tRNA dimethylallyltransferase chr1 GO:0010467 Not Cancer Driver No 61 0.131 121 19 0.157 1
TRMT10C TRMT10C Q7L0Y3 tRNA methyltransferase 10 homolog C chr3 GO:0010467 Not Cancer Driver No 56 0.139 59 10 0.169 2
TRMT5 TRMT5 Q32P41 tRNA (guanine(37)-N1)-methyltransferase chr14 GO:0010467 Not Cancer Driver No 46 0.09 67 5 0.075 2
TRMT61B TRMT61B Q9BVS5 tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial chr2 GO:0010467 Not Cancer Driver No 48 0.101 123 10 0.081 0
TRNT1 TRNT1 Q96Q11 CCA tRNA nucleotidyltransferase 1, mitochondrial chr3 GO:0010467 Not Cancer Driver No 60 0.138 49 8 0.163 7
TSSK1B TSSK1B Q9BXA7 Testis-specific serine/threonine-protein kinase 1 chr5 GO:0010467 Not Cancer Driver No 104 0.283 114 36 0.316 0