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Total number of protein in "GO:0009967" GO term:  855

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAK1 AAK1 Q2M2I8 AP2-associated protein kinase 1 chr2 GO:0009967 Not Cancer Driver No 109 0.113 654 70 0.107 0
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0009967 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABRA ABRA Q8N0Z2 Actin-binding Rho-activating protein chr8 GO:0009967 Not Cancer Driver No 108 0.283 285 86 0.302 0
ACPP_ENST00000336375 ACP3 P15309 Prostatic acid phosphatase chr3 GO:0009967 Not Cancer Driver No 81 0.21 24 5 0.208 0
ACVR1B_ENST00000257963 ACVR1B P36896 Activin receptor type-1B chr12 GO:0009967 Census Yes 114 0.226 0 0 0.0 0
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0009967 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVR2A_ENST00000404590 ACVR2A P27037 Activin receptor type-2A chr2 GO:0009967 Census, Compendium Yes 98 0.191 56 6 0.107 0
ACVR2B ACVR2B Q13705 Activin receptor type-2B chr3 GO:0009967 Not Cancer Driver No 83 0.162 70 14 0.2 2
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0009967 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADA ADA P00813 Adenosine deaminase chr20 GO:0009967 Not Cancer Driver No 50 0.138 44 9 0.205 27
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0009967 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAMTS20 ADAMTS20 P59510 A disintegrin and metalloproteinase with thrombospondin motifs 20 chr12 GO:0009967 Not Cancer Driver No 495 0.259 120 33 0.275 0
ADAMTS3 ADAMTS3 O15072 A disintegrin and metalloproteinase with thrombospondin motifs 3 chr4 GO:0009967 Not Cancer Driver No 253 0.21 295 78 0.264 2
ADCYAP1R1_ENST00000304166 ADCYAP1R1 P41586 Pituitary adenylate cyclase-activating polypeptide type I receptor chr7 GO:0009967 Not Cancer Driver No 127 0.271 0 0 0.0 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0009967 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADGRV1_ENST00000645211 ADGRV1 Q8WXG9 Adhesion G-protein coupled receptor V1 chr5 GO:0009967 Not Cancer Driver No 1124 0.178 496 77 0.155 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0009967 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADIPOR1 ADIPOR1 Q96A54 Adiponectin receptor protein 1 chr1 GO:0009967 Not Cancer Driver No 63 0.168 69 10 0.145 0
ADORA1 ADORA1 P30542 Adenosine receptor A1 chr1 GO:0009967 Not Cancer Driver No 64 0.196 12 4 0.333 0
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0009967 Not Cancer Driver No 23 0.069 0 0 0.0 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0009967 Not Cancer Driver No 130 0.279 40 8 0.2 0
ADRA2A ADRA2A P08913 Alpha-2A adrenergic receptor chr10 GO:0009967 Not Cancer Driver No 67 0.144 161 10 0.062 0
ADRB2 ADRB2 P07550 Beta-2 adrenergic receptor chr5 GO:0009967 Not Cancer Driver No 52 0.126 35 4 0.114 0
AFAP1L2 AFAP1L2 Q8N4X5 Actin filament-associated protein 1-like 2 chr10 GO:0009967 Not Cancer Driver No 86 0.105 558 59 0.106 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0009967 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGPAT1 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 GO:0009967 Not Cancer Driver No 36 0.127 38 5 0.132 0
AGPAT2_ENST00000538402 AGPAT2 O15120 1-acyl-sn-glycerol-3-phosphate acyltransferase beta chr9 GO:0009967 Not Cancer Driver No 25 0.09 23 2 0.087 3
AGR2 AGR2 O95994 Anterior gradient protein 2 homolog chr7 GO:0009967 Not Cancer Driver No 23 0.131 20 2 0.1 0
AGT AGT P01019 Angiotensinogen chr1 GO:0009967 Not Cancer Driver No 85 0.179 33 10 0.303 1
AKAP12 AKAP12 Q02952 A-kinase anchor protein 12 chr6 GO:0009967 Not Cancer Driver No 215 0.121 1770 214 0.121 0
AKAP13_ENST00000394518 AKAP13 Q12802 A-kinase anchor protein 13 chr15 GO:0009967 Not Cancer Driver No 359 0.128 2091 258 0.123 0
AKAP6 AKAP6 Q13023 A-kinase anchor protein 6 chr14 GO:0009967 Not Cancer Driver No 383 0.165 1456 240 0.165 0
ALKAL1 ALKAL1 Q6UXT8 ALK and LTK ligand 1 chr8 GO:0009967 Not Cancer Driver No 18 0.14 49 3 0.061 0
ALKAL2 ALKAL2 Q6UX46 ALK and LTK ligand 2 chr2 GO:0009967 Not Cancer Driver No 7 0.046 31 0 0.0 0
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0009967 Not Cancer Driver No 99 0.146 62 12 0.194 0
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0009967 Not Cancer Driver No 194 0.117 353 36 0.102 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0009967 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANKRD1 ANKRD1 Q15327 Ankyrin repeat domain-containing protein 1 chr10 GO:0009967 Not Cancer Driver No 52 0.163 83 13 0.157 0
ANKRD17 ANKRD17 O75179 Ankyrin repeat domain-containing protein 17 chr4 GO:0009967 Not Cancer Driver No 312 0.12 1790 221 0.123 9
ANKRD6_ENST00000339746 ANKRD6 Q9Y2G4 Ankyrin repeat domain-containing protein 6 chr6 GO:0009967 Not Cancer Driver No 91 0.125 500 61 0.122 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0009967 Not Cancer Driver No 28 0.105 131 8 0.061 3
APPL2_ENST00000258530 APPL2 Q8NEU8 DCC-interacting protein 13-beta chr12 GO:0009967 Not Cancer Driver No 70 0.105 149 14 0.094 0
AR AR P10275 Androgen receptor chrX GO:0009967 Census, Compendium Yes 196 0.213 443 88 0.199 169
AREG AREG P15514 Amphiregulin chr4 GO:0009967 Not Cancer Driver No 28 0.111 149 20 0.134 0
ARHGEF3_ENST00000296315 ARHGEF3 Q9NR81 Rho guanine nucleotide exchange factor 3 chr3 GO:0009967 Not Cancer Driver No 70 0.133 154 17 0.11 0
ARHGEF5 ARHGEF5 Q12774 Rho guanine nucleotide exchange factor 5 chr7 GO:0009967 Not Cancer Driver No 170 0.106 1141 127 0.111 0
ARMC9 ARMC9 Q7Z3E5 LisH domain-containing protein ARMC9 chr2 GO:0009967 Not Cancer Driver No 86 0.105 253 21 0.083 0
ARNT ARNT P27540 Aryl hydrocarbon receptor nuclear translocator chr1 GO:0009967 Census Yes 77 0.098 511 56 0.11 0
ARRB1 ARRB1 P49407 Beta-arrestin-1 chr11 GO:0009967 Not Cancer Driver No 49 0.117 154 13 0.084 0
ASCL1 ASCL1 P50553 Achaete-scute homolog 1 chr12 GO:0009967 Not Cancer Driver No 33 0.14 182 24 0.132 0
ASXL1_ENST00000613218 ASXL1 Q8IXJ9 Polycomb group protein ASXL1 chr20 GO:0009967 Census, Compendium Yes 205 0.133 1300 174 0.134 0
ASXL2_ENST00000435504 ASXL2 Q76L83 Putative Polycomb group protein ASXL2 chr2 GO:0009967 Census, Compendium Yes 209 0.146 1275 174 0.136 0
ATF3_ENST00000366987 ATF3 P18847 Cyclic AMP-dependent transcription factor ATF-3 chr1 GO:0009967 Not Cancer Driver No 23 0.127 118 14 0.119 0
ATF6 ATF6 P18850 Cyclic AMP-dependent transcription factor ATF-6 alpha chr1 GO:0009967 Not Cancer Driver No 88 0.131 468 59 0.126 2
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0009967 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0009967 Census, Compendium Yes 338 0.128 106 14 0.132 1
AUTS2 AUTS2 Q8WXX7 Autism susceptibility gene 2 protein chr7 GO:0009967 Not Cancer Driver No 219 0.174 1218 213 0.175 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0009967 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXL AXL P30530 Tyrosine-protein kinase receptor UFO chr19 GO:0009967 Not Cancer Driver No 168 0.188 341 64 0.188 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0009967 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0009967 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0009967 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0009967 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0009967 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0009967 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCAR3_ENST00000260502 BCAR3 O75815 Breast cancer anti-estrogen resistance protein 3 chr1 GO:0009967 Not Cancer Driver No 102 0.124 395 42 0.106 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0009967 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0009967 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0009967 Census, Compendium Yes 421 0.458 899 408 0.454 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0009967 Not Cancer Driver No 47 0.19 79 19 0.241 1
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0009967 Not Cancer Driver No 45 0.1 190 19 0.1 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0009967 Not Cancer Driver No 23 0.118 74 9 0.122 0
BMP10 BMP10 O95393 Bone morphogenetic protein 10 chr2 GO:0009967 Not Cancer Driver No 88 0.208 87 13 0.149 0
BMP15 BMP15 O95972 Bone morphogenetic protein 15 chrX GO:0009967 Not Cancer Driver No 91 0.232 81 15 0.185 13
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0009967 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP2K BMP2K Q9NSY1 BMP-2-inducible protein kinase chr4 GO:0009967 Not Cancer Driver No 124 0.107 827 89 0.108 0
BMP3 BMP3 P12645 Bone morphogenetic protein 3 chr4 GO:0009967 Not Cancer Driver No 120 0.254 147 48 0.327 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0009967 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0009967 Census Yes 163 0.359 112 62 0.554 0
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0009967 Not Cancer Driver No 95 0.185 226 51 0.226 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0009967 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMP8A BMP8A Q7Z5Y6 Bone morphogenetic protein 8A chr1 GO:0009967 Not Cancer Driver No 26 0.065 93 2 0.022 0
BMP8B BMP8B P34820 Bone morphogenetic protein 8B chr1 GO:0009967 Not Cancer Driver No 21 0.052 90 3 0.033 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0009967 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0009967 Not Cancer Driver No 84 0.167 64 12 0.188 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0009967 Compendium Yes 141 0.136 601 70 0.116 19
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0009967 Not Cancer Driver No 7 0.033 0 0 0.0 0
BTC BTC P35070 Probetacellulin chr4 GO:0009967 Not Cancer Driver No 29 0.163 12 5 0.417 0
C10orf71 CEFIP Q711Q0 Cardiac-enriched FHL2-interacting protein chr10 GO:0009967 Not Cancer Driver No 229 0.16 1356 218 0.161 0
C12orf49 SPRING1 Q9H741 SREBP regulating gene protein chr12 GO:0009967 Not Cancer Driver No 26 0.127 0 0 0.0 0
C1QTNF12 C1QTNF12 Q5T7M4 Adipolin chr1 GO:0009967 Not Cancer Driver No 13 0.043 105 5 0.048 0
C1QTNF4 C1QTNF4 Q9BXJ3 Complement C1q tumor necrosis factor-related protein 4 chr11 GO:0009967 Not Cancer Driver No 25 0.076 91 4 0.044 0
C20orf27_ENST00000379772 C20orf27 Q9GZN8 UPF0687 protein C20orf27 chr20 GO:0009967 Not Cancer Driver No 27 0.155 31 4 0.129 0
C3 C3 P01024 Complement C3 chr19 GO:0009967 Not Cancer Driver No 337 0.203 287 50 0.174 12
CALCR_ENST00000394441 CALCR P30988 Calcitonin receptor chr7 GO:0009967 Not Cancer Driver No 162 0.342 29 9 0.31 0
CAMTA1 CAMTA1 Q9Y6Y1 Calmodulin-binding transcription activator 1 chr1 GO:0009967 Census, Compendium Yes 300 0.179 883 152 0.172 0
CARD11 CARD11 Q9BXL7 Caspase recruitment domain-containing protein 11 chr7 GO:0009967 Census, Compendium Yes 303 0.263 530 140 0.264 5
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0009967 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0009967 Not Cancer Driver No 56 0.149 102 14 0.137 0
CAT CAT P04040 Catalase chr11 GO:0009967 Not Cancer Driver No 70 0.133 176 18 0.102 0
CAV1 CAV1 Q03135 Caveolin-1 chr7 GO:0009967 Not Cancer Driver No 30 0.169 2 0 0.0 0
CAV2 CAV2 P51636 Caveolin-2 chr7 GO:0009967 Not Cancer Driver No 20 0.123 5 2 0.4 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0009967 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0009967 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCBE1 CCBE1 Q6UXH8 Collagen and calcium-binding EGF domain-containing protein 1 chr18 GO:0009967 Not Cancer Driver No 92 0.227 227 58 0.256 5
CCDC88A_ENST00000642200 CCDC88A Q3V6T2 Girdin chr2 GO:0009967 Not Cancer Driver No 226 0.121 1481 173 0.117 0
CCL19 CCL19 Q99731 C-C motif chemokine 19 chr9 GO:0009967 Not Cancer Driver No 10 0.102 7 0 0.0 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0009967 Not Cancer Driver No 33 0.087 12 0 0.0 0
CCN3 CCN3 P48745 CCN family member 3 chr8 GO:0009967 Not Cancer Driver No 66 0.185 19 1 0.053 0
CCR7 CCR7 P32248 C-C chemokine receptor type 7 chr17 GO:0009967 Census, Compendium Yes 50 0.132 0 0 0.0 0
CD180 CD180 Q99467 CD180 antigen chr5 GO:0009967 Not Cancer Driver No 105 0.159 0 0 0.0 0
CD226_ENST00000582621 CD226 Q15762 CD226 antigen chr18 GO:0009967 Not Cancer Driver No 79 0.235 47 11 0.234 0
CD28 CD28 P10747 T-cell-specific surface glycoprotein CD28 chr2 GO:0009967 Census Yes 42 0.191 18 10 0.556 0
CD300LF_ENST00000326165 CD300LF Q8TDQ1 CMRF35-like molecule 1 chr17 GO:0009967 Not Cancer Driver No 36 0.124 88 11 0.125 0
CD3E CD3E P07766 T-cell surface glycoprotein CD3 epsilon chain chr11 GO:0009967 Not Cancer Driver No 28 0.135 72 12 0.167 0
CD4 CD4 P01730 T-cell surface glycoprotein CD4 chr12 GO:0009967 Not Cancer Driver No 69 0.151 56 11 0.196 0
CD40 CD40 P25942 Tumor necrosis factor receptor superfamily member 5 chr20 GO:0009967 Not Cancer Driver No 39 0.141 56 6 0.107 2
CD63_ENST00000552692 CD63 P08962 CD63 antigen chr12 GO:0009967 Not Cancer Driver No 27 0.113 0 0 0.0 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0009967 Census Yes 31 0.105 185 20 0.108 0
CD80_ENST00000478182 CD80 P33681 T-lymphocyte activation antigen CD80 chr3 GO:0009967 Not Cancer Driver No 50 0.174 26 5 0.192 0
CD81 CD81 P60033 CD81 antigen chr11 GO:0009967 Not Cancer Driver No 28 0.119 0 0 0.0 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0009967 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDH3 CDH3 P22223 Cadherin-3 chr16 GO:0009967 Not Cancer Driver No 87 0.105 488 52 0.107 2
CDH5 CDH5 P33151 Cadherin-5 chr16 GO:0009967 Not Cancer Driver No 144 0.184 305 55 0.18 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0009967 Not Cancer Driver No 50 0.099 99 20 0.202 0
CDKN1C CDKN1C P49918 Cyclin-dependent kinase inhibitor 1C chr11 GO:0009967 Not Cancer Driver No 2 0.006 256 1 0.004 7
CDKN2AIP CDKN2AIP Q9NXV6 CDKN2A-interacting protein chr4 GO:0009967 Not Cancer Driver No 53 0.091 352 38 0.108 0
CDKN2B CDKN2B P42772 Cyclin-dependent kinase 4 inhibitor B chr9 GO:0009967 Not Cancer Driver No 15 0.109 67 3 0.045 0
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:0009967 Not Cancer Driver No 365 0.187 931 183 0.197 0
CHERP CHERP Q8IWX8 Calcium homeostasis endoplasmic reticulum protein chr19 GO:0009967 Not Cancer Driver No 109 0.119 707 79 0.112 0
CHGA CHGA P10645 Chromogranin-A chr14 GO:0009967 Not Cancer Driver No 46 0.101 421 44 0.105 0
CHP2 CHP2 O43745 Calcineurin B homologous protein 2 chr16 GO:0009967 Not Cancer Driver No 43 0.219 65 16 0.246 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0009967 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHSY1 CHSY1 Q86X52 Chondroitin sulfate synthase 1 chr15 GO:0009967 Not Cancer Driver No 95 0.118 137 10 0.073 1
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0009967 Not Cancer Driver No 24 0.126 6 1 0.167 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0009967 Not Cancer Driver No 24 0.124 166 21 0.127 0
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0009967 Not Cancer Driver No 23 0.085 230 18 0.078 0
CLEC16A CLEC16A Q2KHT3 Protein CLEC16A chr16 GO:0009967 Not Cancer Driver No 149 0.142 374 53 0.142 0
CLEC7A CLEC7A Q9BXN2 C-type lectin domain family 7 member A chr12 GO:0009967 Not Cancer Driver No 43 0.174 46 2 0.043 0
CMTM3_ENST00000567572 CMTM3 Q96MX0 CKLF-like MARVEL transmembrane domain-containing protein 3 chr16 GO:0009967 Not Cancer Driver No 16 0.088 39 1 0.026 0
CNOT9_ENST00000273064 CNOT9 Q92600 CCR4-NOT transcription complex subunit 9 chr2 GO:0009967 Compendium Yes 42 0.14 30 0 0.0 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0009967 Not Cancer Driver No 155 0.149 370 61 0.165 0
CNTN6_ENST00000350110 CNTN6 Q9UQ52 Contactin-6 chr3 GO:0009967 Not Cancer Driver No 330 0.321 173 59 0.341 0
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0009967 Census Yes 402 0.274 1182 337 0.285 103
CPNE1_ENST00000352393 CPNE1 Q99829 Copine-1 chr20 GO:0009967 Not Cancer Driver No 74 0.138 80 7 0.087 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0009967 Not Cancer Driver No 155 0.121 72 0 0.0 5
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0009967 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CSF1_ENST00000369802 CSF1 P09603 Macrophage colony-stimulating factor 1 chr1 GO:0009967 Not Cancer Driver No 69 0.125 339 46 0.136 0
CSF3 CSF3 P09919 Granulocyte colony-stimulating factor chr17 GO:0009967 Not Cancer Driver No 20 0.097 7 0 0.0 0
CSNK1D CSNK1D P48730 Casein kinase I isoform delta chr17 GO:0009967 Not Cancer Driver No 59 0.142 132 16 0.121 2
CSNK1E CSNK1E P49674 Casein kinase I isoform epsilon chr22 GO:0009967 Not Cancer Driver No 62 0.149 133 18 0.135 0
CSNK2B_ENST00000375866 CSNK2B P67870 Casein kinase II subunit beta chr6 GO:0009967 Not Cancer Driver No 20 0.093 19 0 0.0 4
CTBP2_ENST00000494626 CTBP2 P56545 C-terminal-binding protein 2 chr10 GO:0009967 Not Cancer Driver No 48 0.108 94 4 0.043 0
CTNNA1 CTNNA1 P35221 Catenin alpha-1 chr5 GO:0009967 Census Yes 126 0.139 268 35 0.131 4
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0009967 Census, Compendium Yes 415 0.531 288 301 1.045 14
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:0009967 Not Cancer Driver No 34 0.093 0 0 0.0 31
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0009967 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0009967 Census, Compendium Yes 62 0.176 5 1 0.2 0
CXorf21 TASL Q9HAI6 TLR adapter interacting with SLC15A4 on the lysosome chrX GO:0009967 Not Cancer Driver No 73 0.243 66 21 0.318 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0009967 Not Cancer Driver No 26 0.133 66 2 0.03 12
CYFIP1_ENST00000610365 CYFIP1 Q7L576 Cytoplasmic FMR1-interacting protein 1 chr15 GO:0009967 Not Cancer Driver No 46 0.037 96 0 0.0 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0009967 Not Cancer Driver No 211 0.165 86 11 0.128 3
CYP27B1 CYP27B1 O15528 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial chr12 GO:0009967 Not Cancer Driver No 71 0.14 79 13 0.165 18
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0009967 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0009967 Not Cancer Driver No 131 0.11 681 68 0.1 0
DCDC2 DCDC2 Q9UHG0 Doublecortin domain-containing protein 2 chr6 GO:0009967 Not Cancer Driver No 72 0.151 264 41 0.155 2
DCN DCN P07585 Decorin chr12 GO:0009967 Not Cancer Driver No 96 0.267 81 26 0.321 0
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0009967 Census Yes 29 0.172 160 27 0.169 0
DDX3X_ENST00000629496 DDX3X O00571 ATP-dependent RNA helicase DDX3X chrX GO:0009967 Census, Compendium Yes 133 0.201 301 47 0.156 18
DDX5 DDX5 P17844 Probable ATP-dependent RNA helicase DDX5 chr17 GO:0009967 Census Yes 74 0.121 225 23 0.102 0
DDX60 DDX60 Q8IY21 Probable ATP-dependent RNA helicase DDX60 chr4 GO:0009967 Not Cancer Driver No 224 0.131 131 12 0.092 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0009967 Not Cancer Driver No 160 0.132 441 60 0.136 0
DHX58 DHX58 Q96C10 ATP-dependent RNA helicase DHX58 chr17 GO:0009967 Not Cancer Driver No 62 0.091 84 8 0.095 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0009967 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0009967 Not Cancer Driver No 116 0.16 232 55 0.237 0
DLG5 DLG5 Q8TDM6 Disks large homolog 5 chr10 GO:0009967 Not Cancer Driver No 230 0.12 1119 135 0.121 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0009967 Not Cancer Driver No 115 0.159 145 24 0.166 1
DLL4 DLL4 Q9NR61 Delta-like protein 4 chr15 GO:0009967 Not Cancer Driver No 75 0.109 73 15 0.205 7
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0009967 Not Cancer Driver No 53 0.131 348 46 0.132 0
DNM1L_ENST00000549701 DNM1L O00429 Dynamin-1-like protein chr12 GO:0009967 Not Cancer Driver No 67 0.091 212 23 0.108 7
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0009967 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0009967 Not Cancer Driver No 88 0.22 45 17 0.378 0
DSTYK DSTYK Q6XUX3 Dual serine/threonine and tyrosine protein kinase chr1 GO:0009967 Not Cancer Driver No 112 0.121 112 4 0.036 2
DUSP19 DUSP19 Q8WTR2 Dual specificity protein phosphatase 19 chr2 GO:0009967 Not Cancer Driver No 34 0.157 15 5 0.333 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0009967 Not Cancer Driver No 73 0.105 434 38 0.088 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0009967 Not Cancer Driver No 96 0.13 514 64 0.125 0
DVL3 DVL3 Q92997 Segment polarity protein dishevelled homolog DVL-3 chr3 GO:0009967 Not Cancer Driver No 97 0.135 437 58 0.133 0
DYNC1LI1 DYNC1LI1 Q9Y6G9 Cytoplasmic dynein 1 light intermediate chain 1 chr3 GO:0009967 Not Cancer Driver No 46 0.088 208 20 0.096 0
DYNC2H1_ENST00000375735 DYNC2H1 Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 chr11 GO:0009967 Not Cancer Driver No 510 0.118 282 15 0.053 34
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0009967 Not Cancer Driver No 37 0.175 97 20 0.206 3
EEF1E1 EEF1E1 O43324 Eukaryotic translation elongation factor 1 epsilon-1 chr6 GO:0009967 Not Cancer Driver No 27 0.155 11 1 0.091 0
EGF EGF P01133 Pro-epidermal growth factor chr4 GO:0009967 Not Cancer Driver No 184 0.152 191 25 0.131 1
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0009967 Census, Compendium Yes 444 0.367 223 35 0.157 1
EIF2A EIF2A Q9BY44 Eukaryotic translation initiation factor 2A chr3 GO:0009967 Not Cancer Driver No 51 0.087 162 19 0.117 0
EIF5A_ENST00000419711 EIF5A P63241 Eukaryotic translation initiation factor 5A-1 chr17 GO:0009967 Not Cancer Driver No 37 0.24 21 5 0.238 5
EMC10 EMC10 Q5UCC4 ER membrane protein complex subunit 10 chr19 GO:0009967 Not Cancer Driver No 25 0.095 109 15 0.138 0
EMP2_ENST00000536829 EMP2 P54851 Epithelial membrane protein 2 chr16 GO:0009967 Not Cancer Driver No 24 0.144 0 0 0.0 2
ENG ENG P17813 Endoglin chr9 GO:0009967 Not Cancer Driver No 60 0.091 114 15 0.132 32
ENHO ENHO Q6UWT2 Adropin chr9 GO:0009967 Not Cancer Driver No 12 0.158 32 5 0.156 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0009967 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPGN EPGN Q6UW88 Epigen chr4 GO:0009967 Not Cancer Driver No 16 0.104 0 0 0.0 0
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0009967 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPN2 EPN2 O95208 Epsin-2 chr17 GO:0009967 Not Cancer Driver No 73 0.114 543 61 0.112 0
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0009967 Census, Compendium Yes 298 0.222 396 70 0.177 3
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0009967 Census, Compendium Yes 428 0.327 323 116 0.359 2
EREG EREG O14944 Proepiregulin chr4 GO:0009967 Not Cancer Driver No 26 0.154 10 3 0.3 0
ERFE ERFE Q4G0M1 Erythroferrone chr2 GO:0009967 Not Cancer Driver No 4 0.011 179 0 0.0 0
ERN1 ERN1 O75460 Serine/threonine-protein kinase/endoribonuclease IRE1 chr17 GO:0009967 Not Cancer Driver No 125 0.128 250 28 0.112 0
ERN2 ERN2 Q76MJ5 Serine/threonine-protein kinase/endoribonuclease IRE2 chr16 GO:0009967 Not Cancer Driver No 192 0.207 213 45 0.211 0
ESM1 ESM1 Q9NQ30 Endothelial cell-specific molecule 1 chr5 GO:0009967 Not Cancer Driver No 44 0.239 37 11 0.297 0
EVC EVC P57679 Ellis-van Creveld syndrome protein chr4 GO:0009967 Not Cancer Driver No 143 0.144 373 60 0.161 4
F11R F11R Q9Y624 Junctional adhesion molecule A chr1 GO:0009967 Not Cancer Driver No 47 0.157 72 15 0.208 0
F2 F2 P00734 Prothrombin chr11 GO:0009967 Not Cancer Driver No 115 0.185 97 25 0.258 10
F2R F2R P25116 Proteinase-activated receptor 1 chr5 GO:0009967 Not Cancer Driver No 73 0.172 19 2 0.105 0
F2RL1 F2RL1 P55085 Proteinase-activated receptor 2 chr5 GO:0009967 Not Cancer Driver No 55 0.139 7 2 0.286 0
F2RL2 F2RL2 O00254 Proteinase-activated receptor 3 chr5 GO:0009967 Not Cancer Driver No 54 0.144 0 0 0.0 0
F2RL3 F2RL3 Q96RI0 Proteinase-activated receptor 4 chr19 GO:0009967 Not Cancer Driver No 43 0.112 46 4 0.087 0
F3 F3 P13726 Tissue factor chr1 GO:0009967 Not Cancer Driver No 28 0.095 61 7 0.115 0
F7 F7 P08709 Coagulation factor VII chr13 GO:0009967 Not Cancer Driver No 74 0.159 50 7 0.14 108
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0009967 Not Cancer Driver No 15 0.111 4 4 1.0 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0009967 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0009967 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAM92A CIBAR1 A1XBS5 CBY1-interacting BAR domain-containing protein 1 chr8 GO:0009967 Not Cancer Driver No 32 0.111 128 17 0.133 0
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0009967 Not Cancer Driver No 65 0.231 94 18 0.191 1
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0009967 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXL15 FBXL15 Q9H469 F-box/LRR-repeat protein 15 chr10 GO:0009967 Not Cancer Driver No 9 0.03 16 1 0.062 0
FBXW7_ENST00000603841 FBXW7 Q969H0 F-box/WD repeat-containing protein 7 chr4 GO:0009967 Census, Compendium Yes 322 0.455 230 38 0.165 0
FERMT1 FERMT1 Q9BQL6 Fermitin family homolog 1 chr20 GO:0009967 Not Cancer Driver No 100 0.148 65 8 0.123 2
FFAR4_ENST00000371481 FFAR4 Q5NUL3 Free fatty acid receptor 4 chr10 GO:0009967 Not Cancer Driver No 47 0.13 0 0 0.0 0
FGD2 FGD2 Q7Z6J4 FYVE, RhoGEF and PH domain-containing protein 2 chr6 GO:0009967 Not Cancer Driver No 113 0.173 158 26 0.165 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0009967 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF18 FGF18 O76093 Fibroblast growth factor 18 chr5 GO:0009967 Not Cancer Driver No 40 0.193 57 14 0.246 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0009967 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF23 FGF23 Q9GZV9 Fibroblast growth factor 23 chr12 GO:0009967 Not Cancer Driver No 84 0.335 97 51 0.526 7
FGF2_ENST00000614010 FGF2 P09038 Fibroblast growth factor 2 chr4 GO:0009967 Not Cancer Driver No 18 0.062 183 5 0.027 0
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0009967 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGF9 FGF9 P31371 Fibroblast growth factor 9 chr13 GO:0009967 Not Cancer Driver No 41 0.197 43 10 0.233 1
FGFBP1 FGFBP1 Q14512 Fibroblast growth factor-binding protein 1 chr4 GO:0009967 Not Cancer Driver No 28 0.12 81 8 0.099 0
FGFBP3 FGFBP3 Q8TAT2 Fibroblast growth factor-binding protein 3 chr10 GO:0009967 Not Cancer Driver No 6 0.023 175 3 0.017 0
FGFR1_ENST00000447712 FGFR1 P11362 Fibroblast growth factor receptor 1 chr8 GO:0009967 Census, Compendium Yes 152 0.185 230 43 0.187 74
FGR_ENST00000374004 FGR P09769 Tyrosine-protein kinase Fgr chr1 GO:0009967 Not Cancer Driver No 85 0.161 52 8 0.154 0
FIS1 FIS1 Q9Y3D6 Mitochondrial fission 1 protein chr7 GO:0009967 Not Cancer Driver No 25 0.164 6 0 0.0 0
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 GO:0009967 Not Cancer Driver No 71 0.172 160 25 0.156 0
FLCN FLCN Q8NFG4 Folliculin chr17 GO:0009967 Census, Compendium Yes 59 0.102 157 19 0.121 5
FLNA FLNA P21333 Filamin-A chrX GO:0009967 Census Yes 416 0.157 1456 214 0.147 28
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0009967 Not Cancer Driver No 43 0.101 122 15 0.123 0
FLT1 FLT1 P17948 Vascular endothelial growth factor receptor 1 chr13 GO:0009967 Not Cancer Driver No 299 0.223 103 20 0.194 0
FLT3 FLT3 P36888 Receptor-type tyrosine-protein kinase FLT3 chr13 GO:0009967 Census, Compendium Yes 200 0.201 64 27 0.422 0
FLT4 FLT4 P35916 Vascular endothelial growth factor receptor 3 chr5 GO:0009967 Census, Compendium Yes 253 0.186 259 41 0.158 13
FN1 FN1 P02751 Fibronectin chr2 GO:0009967 Compendium Yes 394 0.159 1243 185 0.149 8
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0009967 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXD1 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0009967 Not Cancer Driver No 10 0.022 259 5 0.019 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0009967 Census, Compendium Yes 109 0.161 448 71 0.158 3
FRMD1 FRMD1 Q8N878 FERM domain-containing protein 1 chr6 GO:0009967 Not Cancer Driver No 82 0.149 259 36 0.139 0
FRMD7 FRMD7 Q6ZUT3 FERM domain-containing protein 7 chrX GO:0009967 Not Cancer Driver No 147 0.206 256 59 0.23 25
FSHR FSHR P23945 Follicle-stimulating hormone receptor chr2 GO:0009967 Not Cancer Driver No 226 0.325 28 11 0.393 16
FZD10 FZD10 Q9ULW2 Frizzled-10 chr12 GO:0009967 Not Cancer Driver No 148 0.255 65 15 0.231 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0009967 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0009967 Not Cancer Driver No 45 0.077 58 4 0.069 0
FZD8 FZD8 Q9H461 Frizzled-8 chr10 GO:0009967 Not Cancer Driver No 72 0.104 146 3 0.021 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0009967 Not Cancer Driver No 10 0.061 39 5 0.128 0
GADD45B GADD45B O75293 Growth arrest and DNA damage-inducible protein GADD45 beta chr19 GO:0009967 Not Cancer Driver No 9 0.056 14 0 0.0 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:0009967 Not Cancer Driver No 13 0.082 20 2 0.1 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0009967 Not Cancer Driver No 82 0.121 42 6 0.143 0
GAS8 GAS8 O95995 Dynein regulatory complex subunit 4 chr16 GO:0009967 Not Cancer Driver No 54 0.113 232 29 0.125 1
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0009967 Census, Compendium Yes 111 0.251 364 87 0.239 2
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0009967 Not Cancer Driver No 48 0.109 301 34 0.113 18
GATA5 GATA5 Q9BWX5 Transcription factor GATA-5 chr20 GO:0009967 Not Cancer Driver No 40 0.101 268 24 0.09 9
GATA6 GATA6 Q92908 Transcription factor GATA-6 chr18 GO:0009967 Not Cancer Driver No 57 0.096 476 51 0.107 10
GDF1 GDF1 P27539 Embryonic growth/differentiation factor 1 chr19 GO:0009967 Not Cancer Driver No 8 0.022 144 5 0.035 6
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0009967 Not Cancer Driver No 40 0.098 109 7 0.064 1
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0009967 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0009967 Not Cancer Driver No 79 0.217 3 3 1.0 5
GDF5_ENST00000374369 GDF5 P43026 Growth/differentiation factor 5 chr20 GO:0009967 Not Cancer Driver No 104 0.208 255 50 0.196 24
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0009967 Not Cancer Driver No 91 0.2 225 46 0.204 14
GDF7 GDF7 Q7Z4P5 Growth/differentiation factor 7 chr2 GO:0009967 Not Cancer Driver No 33 0.073 213 8 0.038 0
GDF9 GDF9 O60383 Growth/differentiation factor 9 chr5 GO:0009967 Not Cancer Driver No 72 0.159 53 15 0.283 0
GEN1_ENST00000381254 GEN1 Q17RS7 Flap endonuclease GEN homolog 1 chr2 GO:0009967 Not Cancer Driver No 109 0.12 339 52 0.153 0
GFI1 GFI1 Q99684 Zinc finger protein Gfi-1 chr1 GO:0009967 Not Cancer Driver No 57 0.135 199 29 0.146 2
GH1 GH1 P01241 Somatotropin chr17 GO:0009967 Not Cancer Driver No 54 0.249 24 9 0.375 15
GHRHR GHRHR Q02643 Growth hormone-releasing hormone receptor chr7 GO:0009967 Not Cancer Driver No 41 0.097 3 0 0.0 5
GHRH_ENST00000237527 GHRH P01286 Somatoliberin chr20 GO:0009967 Not Cancer Driver No 13 0.12 36 4 0.111 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0009967 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0009967 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0009967 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0009967 Not Cancer Driver No 47 0.141 138 17 0.123 0
GIPR GIPR P48546 Gastric inhibitory polypeptide receptor chr19 GO:0009967 Not Cancer Driver No 45 0.097 41 0 0.0 0
GKAP1 GKAP1 Q5VSY0 G kinase-anchoring protein 1 chr9 GO:0009967 Not Cancer Driver No 39 0.107 279 29 0.104 0
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0009967 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GNAI2 GNAI2 P04899 Guanine nucleotide-binding protein G(i) subunit alpha-2 chr3 GO:0009967 Compendium Yes 50 0.141 24 0 0.0 0
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0009967 Census Yes 89 0.153 86 11 0.128 1
GPER1 GPER1 Q99527 G-protein coupled estrogen receptor 1 chr7 GO:0009967 Not Cancer Driver No 65 0.173 13 5 0.385 0
GPR137B GPR137B O60478 Integral membrane protein GPR137B chr1 GO:0009967 Not Cancer Driver No 49 0.123 47 1 0.021 0
GPR137C GPR137C Q8N3F9 Integral membrane protein GPR137C chr14 GO:0009967 Not Cancer Driver No 41 0.096 47 0 0.0 0
GPR137_ENST00000313074 GPR137 Q96N19 Integral membrane protein GPR137 chr11 GO:0009967 Not Cancer Driver No 66 0.158 41 11 0.268 0
GPR17 GPR17 Q13304 Uracil nucleotide/cysteinyl leukotriene receptor chr2 GO:0009967 Not Cancer Driver No 57 0.155 16 4 0.25 0
GPR174_ENST00000276077 GPR174 Q9BXC1 Probable G-protein coupled receptor 174 chrX GO:0009967 Not Cancer Driver No 115 0.345 0 0 0.0 0
GPR18_ENST00000397470 GPR18 Q14330 N-arachidonyl glycine receptor chr13 GO:0009967 Not Cancer Driver No 36 0.109 0 0 0.0 0
GPR20 GPR20 Q99678 G-protein coupled receptor 20 chr8 GO:0009967 Not Cancer Driver No 77 0.215 44 11 0.25 0
GPR27 GPR27 Q9NS67 Probable G-protein coupled receptor 27 chr3 GO:0009967 Not Cancer Driver No 26 0.069 23 1 0.043 0
GPR3 GPR3 P46089 G-protein coupled receptor 3 chr1 GO:0009967 Not Cancer Driver No 38 0.115 13 1 0.077 0
GPR35_ENST00000403859 GPR35 Q9HC97 G-protein coupled receptor 35 chr2 GO:0009967 Not Cancer Driver No 57 0.184 0 0 0.0 0
GPR4 GPR4 P46093 G-protein coupled receptor 4 chr19 GO:0009967 Not Cancer Driver No 57 0.157 44 8 0.182 0
GPR55 GPR55 Q9Y2T6 G-protein coupled receptor 55 chr2 GO:0009967 Not Cancer Driver No 64 0.201 0 0 0.0 0
GPR61_ENST00000618721 GPR61 Q9BZJ8 G-protein coupled receptor 61 chr1 GO:0009967 Not Cancer Driver No 72 0.16 103 23 0.223 0
GPR62 GPR62 Q9BZJ7 G-protein coupled receptor 62 chr3 GO:0009967 Not Cancer Driver No 20 0.054 52 9 0.173 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0009967 Not Cancer Driver No 70 0.208 0 0 0.0 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0009967 Not Cancer Driver No 29 0.089 319 26 0.082 0
GRB10_ENST00000401949 GRB10 Q13322 Growth factor receptor-bound protein 10 chr7 GO:0009967 Not Cancer Driver No 94 0.158 220 38 0.173 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0009967 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRP GRP P07492 Gastrin-releasing peptide chr18 GO:0009967 Not Cancer Driver No 37 0.25 112 22 0.196 0
GSDME_ENST00000409775 GSDME O60443 Gasdermin-E chr7 GO:0009967 Not Cancer Driver No 81 0.163 14 3 0.214 0
GSK3A GSK3A P49840 Glycogen synthase kinase-3 alpha chr19 GO:0009967 Not Cancer Driver No 55 0.114 180 8 0.044 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0009967 Not Cancer Driver No 44 0.145 210 26 0.124 1
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0009967 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCY1A1_ENST00000513574 GUCY1A1 Q02108 Guanylate cyclase soluble subunit alpha-1 chr4 GO:0009967 Not Cancer Driver No 181 0.262 54 8 0.148 0
GUCY1A2_ENST00000526355 GUCY1A2 P33402 Guanylate cyclase soluble subunit alpha-2 chr11 GO:0009967 Not Cancer Driver No 191 0.261 187 48 0.257 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0009967 Not Cancer Driver No 47 0.217 124 29 0.234 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0009967 Not Cancer Driver No 97 0.145 454 60 0.132 0
HAX1 HAX1 O00165 HCLS1-associated protein X-1 chr1 GO:0009967 Not Cancer Driver No 44 0.158 219 32 0.146 2
HBEGF HBEGF Q99075 Proheparin-binding EGF-like growth factor chr5 GO:0009967 Not Cancer Driver No 16 0.077 63 3 0.048 0
HCLS1 HCLS1 P14317 Hematopoietic lineage cell-specific protein chr3 GO:0009967 Not Cancer Driver No 103 0.212 446 94 0.211 0
HCST HCST Q9UBK5 Hematopoietic cell signal transducer chr19 GO:0009967 Not Cancer Driver No 6 0.065 12 0 0.0 0
HES1 HES1 Q14469 Transcription factor HES-1 chr3 GO:0009967 Not Cancer Driver No 37 0.132 226 32 0.142 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0009967 Not Cancer Driver No 1 0.006 73 0 0.0 0
HEXIM1 HEXIM1 O94992 Protein HEXIM1 chr17 GO:0009967 Not Cancer Driver No 40 0.111 352 40 0.114 0
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0009967 Not Cancer Driver No 55 0.158 27 2 0.074 11
HGF_ENST00000644543 HGF P14210 Hepatocyte growth factor chr7 GO:0009967 Compendium Yes 233 0.32 43 16 0.372 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 GO:0009967 Not Cancer Driver No 24 0.033 361 6 0.017 0
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0009967 Census Yes 118 0.143 435 51 0.117 0
HINT1 HINT1 P49773 Adenosine 5'-monophosphoramidase HINT1 chr5 GO:0009967 Not Cancer Driver No 11 0.087 6 0 0.0 6
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 GO:0009967 Census, Compendium Yes 137 0.132 510 70 0.137 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0009967 Not Cancer Driver No 94 0.088 524 34 0.065 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0009967 Not Cancer Driver No 154 0.129 686 96 0.14 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0009967 Not Cancer Driver No 25 0.116 203 20 0.099 0
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 GO:0009967 Not Cancer Driver No 46 0.13 243 32 0.132 0
HPX HPX P02790 Hemopexin chr11 GO:0009967 Not Cancer Driver No 60 0.13 53 8 0.151 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0009967 Census, Compendium Yes 100 0.138 254 43 0.169 0
HSPA1A HSPA1A P0DMV8 Heat shock 70 kDa protein 1A chr6 GO:0009967 Not Cancer Driver No 24 0.037 200 13 0.065 0
HSPA1B HSPA1B P0DMV9 Heat shock 70 kDa protein 1B chr6 GO:0009967 Not Cancer Driver No 15 0.023 200 5 0.025 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0009967 Compendium Yes 44 0.096 127 9 0.071 2
HTT HTT P42858 Huntingtin chr4 GO:0009967 Not Cancer Driver No 336 0.107 666 69 0.104 2
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0009967 Not Cancer Driver No 22 0.247 10 2 0.2 0
IFI35_ENST00000415816 IFI35 P80217 Interferon-induced 35 kDa protein chr17 GO:0009967 Not Cancer Driver No 33 0.115 63 10 0.159 0
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0009967 Not Cancer Driver No 219 0.125 96 10 0.104 8
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0009967 Not Cancer Driver No 183 0.134 265 37 0.14 6
IGF1_ENST00000307046 IGF1 P05019 Insulin-like growth factor I chr12 GO:0009967 Not Cancer Driver No 45 0.231 87 23 0.264 0
IGF2_ENST00000641326 IGF2 P01344 Insulin-like growth factor II chr11 GO:0009967 Not Cancer Driver No 39 0.217 44 12 0.273 0
IGFBP4 IGFBP4 P22692 Insulin-like growth factor-binding protein 4 chr17 GO:0009967 Not Cancer Driver No 24 0.093 106 17 0.16 0
IGFBP5 IGFBP5 P24593 Insulin-like growth factor-binding protein 5 chr2 GO:0009967 Not Cancer Driver No 27 0.099 112 17 0.152 0
IGSF11 IGSF11 Q5DX21 Immunoglobulin superfamily member 11 chr3 GO:0009967 Not Cancer Driver No 98 0.227 159 28 0.176 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0009967 Not Cancer Driver No 58 0.141 111 15 0.135 6
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0009967 Not Cancer Driver No 108 0.151 76 13 0.171 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0009967 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL18 IL18 Q14116 Interleukin-18 chr11 GO:0009967 Not Cancer Driver No 19 0.098 16 3 0.188 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:0009967 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0009967 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL1R1 IL1R1 P14778 Interleukin-1 receptor type 1 chr2 GO:0009967 Not Cancer Driver No 77 0.135 59 8 0.136 0
IL20RA IL20RA Q9UHF4 Interleukin-20 receptor subunit alpha chr6 GO:0009967 Not Cancer Driver No 72 0.13 231 29 0.126 0
IL6ST_ENST00000336909 IL6ST P40189 Interleukin-6 receptor subunit beta chr5 GO:0009967 Census, Compendium Yes 102 0.111 315 40 0.127 2
IL7 IL7 P13232 Interleukin-7 chr8 GO:0009967 Not Cancer Driver No 29 0.164 19 4 0.211 0
ILK_ENST00000299421 ILK Q13418 Integrin-linked protein kinase chr11 GO:0009967 Not Cancer Driver No 45 0.1 71 9 0.127 0
ING2 ING2 Q9H160 Inhibitor of growth protein 2 chr4 GO:0009967 Not Cancer Driver No 33 0.118 169 26 0.154 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0009967 Not Cancer Driver No 31 0.124 108 15 0.139 0
INHA INHA P05111 Inhibin alpha chain chr2 GO:0009967 Not Cancer Driver No 48 0.131 144 15 0.104 0
INHBA_ENST00000442711 INHBA P08476 Inhibin beta A chain chr7 GO:0009967 Not Cancer Driver No 148 0.347 154 63 0.409 0
INHBB INHBB P09529 Inhibin beta B chain chr2 GO:0009967 Not Cancer Driver No 61 0.15 98 5 0.051 0
INHBC INHBC P55103 Inhibin beta C chain chr12 GO:0009967 Not Cancer Driver No 52 0.148 35 3 0.086 0
INHBE INHBE P58166 Inhibin beta E chain chr12 GO:0009967 Not Cancer Driver No 52 0.149 85 12 0.141 0
INS INS P01308 Insulin chr11 GO:0009967 Not Cancer Driver No 15 0.136 5 1 0.2 22
INSL3_ENST00000317306 INSL3 P51460 Insulin-like 3 chr19 GO:0009967 Not Cancer Driver No 18 0.137 34 12 0.353 3
INSR INSR P06213 Insulin receptor chr19 GO:0009967 Not Cancer Driver No 190 0.137 280 57 0.204 64
INTU INTU Q9ULD6 Protein inturned chr4 GO:0009967 Not Cancer Driver No 146 0.155 282 52 0.184 0
IQCJ-SCHIP1 IQCJ-SCHIP1 B3KU38 IQCJ-SCHIP1 readthrough transcript protein chr3 GO:0009967 Not Cancer Driver No 76 0.135 517 71 0.137 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0009967 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0009967 Not Cancer Driver No 43 0.085 253 19 0.075 1
IRGM IRGM A1A4Y4 Immunity-related GTPase family M protein chr5 GO:0009967 Not Cancer Driver No 9 0.05 45 1 0.022 0
IRS1 IRS1 P35568 Insulin receptor substrate 1 chr2 GO:0009967 Not Cancer Driver No 161 0.13 1072 133 0.124 2
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0009967 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0009967 Not Cancer Driver No 292 0.275 114 26 0.228 1
ITGAV ITGAV P06756 Integrin alpha-V chr2 GO:0009967 Census Yes 153 0.146 92 9 0.098 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0009967 Not Cancer Driver No 26 0.13 58 11 0.19 0
ITGB3 ITGB3 P05106 Integrin beta-3 chr17 GO:0009967 Not Cancer Driver No 124 0.157 66 5 0.076 30
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0009967 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0009967 Not Cancer Driver No 126 0.102 158 24 0.152 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0009967 Census, Compendium Yes 136 0.12 59 5 0.085 5
JCAD JCAD Q9P266 Junctional protein associated with coronary artery disease chr10 GO:0009967 Not Cancer Driver No 291 0.214 1337 290 0.217 0
KCNN4 KCNN4 O15554 Intermediate conductance calcium-activated potassium channel protein 4 chr19 GO:0009967 Not Cancer Driver No 60 0.141 31 6 0.194 3
KDR KDR P35968 Vascular endothelial growth factor receptor 2 chr4 GO:0009967 Census, Compendium Yes 357 0.263 275 55 0.2 2
KIAA0319_ENST00000543707 KIAA0319 Q5VV43 Dyslexia-associated protein KIAA0319 chr6 GO:0009967 Not Cancer Driver No 204 0.19 492 85 0.173 0
KIAA1324L ELAPOR2 A8MWY0 Endosome/lysosome-associated apoptosis and autophagy regulator family member 2 chr7 GO:0009967 Not Cancer Driver No 170 0.165 74 6 0.081 0
KIF7 KIF7 Q2M1P5 Kinesin-like protein KIF7 chr15 GO:0009967 Not Cancer Driver No 150 0.112 844 104 0.123 5
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0009967 Census, Compendium Yes 226 0.232 83 33 0.398 21
KL KL Q9UEF7 Klotho chr13 GO:0009967 Not Cancer Driver No 175 0.173 104 5 0.048 1
KLB KLB Q86Z14 Beta-klotho chr4 GO:0009967 Not Cancer Driver No 139 0.133 6 1 0.167 0
KLF14 KLF14 Q8TD94 Krueppel-like factor 14 chr7 GO:0009967 Not Cancer Driver No 24 0.074 264 20 0.076 0
KLF2 KLF2 Q9Y5W3 Krueppel-like factor 2 chr19 GO:0009967 Not Cancer Driver No 13 0.037 280 4 0.014 0
KLHL22 KLHL22 Q53GT1 Kelch-like protein 22 chr22 GO:0009967 Not Cancer Driver No 90 0.142 50 8 0.16 0
KLK14_ENST00000156499 KLK14 Q9P0G3 Kallikrein-14 chr19 GO:0009967 Not Cancer Driver No 41 0.154 29 6 0.207 0
KLK5_ENST00000593428 KLK5 Q9Y337 Kallikrein-5 chr19 GO:0009967 Not Cancer Driver No 69 0.235 75 16 0.213 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0009967 Not Cancer Driver No 62 0.254 28 12 0.429 0
KMT2D KMT2D O14686 Histone-lysine N-methyltransferase 2D chr12 GO:0009967 Census, Compendium Yes 773 0.14 4386 552 0.126 13
KRAS KRAS P01116 GTPase KRas chr12 GO:0009967 Census, Compendium Yes 788 4.169 7 2 0.286 27
LACRT LACRT Q9GZZ8 Extracellular glycoprotein lacritin chr12 GO:0009967 Not Cancer Driver No 38 0.275 90 27 0.3 0
LAMTOR5_ENST00000602318 LAMTOR5 O43504 Ragulator complex protein LAMTOR5 chr1 GO:0009967 Not Cancer Driver No 10 0.11 17 0 0.0 0
LANCL2 LANCL2 Q9NS86 LanC-like protein 2 chr7 GO:0009967 Not Cancer Driver No 71 0.158 44 5 0.114 0
LAPTM5 LAPTM5 Q13571 Lysosomal-associated transmembrane protein 5 chr1 GO:0009967 Not Cancer Driver No 46 0.176 16 6 0.375 0
LARS LARS1 Q9P2J5 Leucine--tRNA ligase, cytoplasmic chr5 GO:0009967 Not Cancer Driver No 133 0.113 97 10 0.103 1
LBP LBP P18428 Lipopolysaccharide-binding protein chr20 GO:0009967 Not Cancer Driver No 84 0.175 6 0 0.0 0
LBX2 LBX2 Q6XYB7 Transcription factor LBX2 chr2 GO:0009967 Not Cancer Driver No 16 0.081 139 7 0.05 0
LCK LCK P06239 Tyrosine-protein kinase Lck chr1 GO:0009967 Census Yes 86 0.169 94 13 0.138 1
LEFTY1 LEFTY1 O75610 Left-right determination factor 1 chr1 GO:0009967 Not Cancer Driver No 55 0.15 65 8 0.123 0
LEFTY2 LEFTY2 O00292 Left-right determination factor 2 chr1 GO:0009967 Not Cancer Driver No 38 0.104 54 4 0.074 1
LEP LEP P41159 Leptin chr7 GO:0009967 Not Cancer Driver No 29 0.174 0 0 0.0 2
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0009967 Not Cancer Driver No 37 0.098 65 1 0.015 1
LIMS1_ENST00000393310 LIMS1 P48059 LIM and senescent cell antigen-like-containing domain protein 1 chr2 GO:0009967 Not Cancer Driver No 34 0.105 0 0 0.0 0
LIMS2_ENST00000355119 LIMS2 Q7Z4I7 LIM and senescent cell antigen-like-containing domain protein 2 chr2 GO:0009967 Not Cancer Driver No 55 0.161 8 0 0.0 0
LMCD1 LMCD1 Q9NZU5 LIM and cysteine-rich domains protein 1 chr3 GO:0009967 Not Cancer Driver No 63 0.173 110 24 0.218 0
LMO3_ENST00000534946 LMO3 Q8TAP4 LIM domain only protein 3 chr12 GO:0009967 Not Cancer Driver No 30 0.207 1 0 0.0 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0009967 Not Cancer Driver No 91 0.121 86 17 0.198 0
LPAR1_ENST00000358883 LPAR1 Q92633 Lysophosphatidic acid receptor 1 chr9 GO:0009967 Not Cancer Driver No 79 0.217 21 6 0.286 0
LPAR4 LPAR4 Q99677 Lysophosphatidic acid receptor 4 chrX GO:0009967 Compendium Yes 123 0.332 10 3 0.3 0
LPAR6_ENST00000620633 LPAR6 P43657 Lysophosphatidic acid receptor 6 chr13 GO:0009967 Not Cancer Driver No 39 0.113 0 0 0.0 3
LRG1 LRG1 P02750 Leucine-rich alpha-2-glycoprotein chr19 GO:0009967 Not Cancer Driver No 63 0.182 29 8 0.276 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0009967 Not Cancer Driver No 519 0.205 90 17 0.189 23
LSM14A_ENST00000433627 LSM14A Q8ND56 Protein LSM14 homolog A chr19 GO:0009967 Census Yes 67 0.145 408 63 0.154 0
LTF LTF P02788 Lactotransferrin chr3 GO:0009967 Not Cancer Driver No 131 0.185 21 4 0.19 0
LY86 LY86 O95711 Lymphocyte antigen 86 chr6 GO:0009967 Not Cancer Driver No 29 0.179 0 0 0.0 0
LY96 LY96 Q9Y6Y9 Lymphocyte antigen 96 chr8 GO:0009967 Not Cancer Driver No 37 0.231 0 0 0.0 0
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0009967 Census Yes 95 0.186 84 12 0.143 0
MAD1L1_ENST00000399654 MAD1L1 Q9Y6D9 Mitotic spindle assembly checkpoint protein MAD1 chr7 GO:0009967 Not Cancer Driver No 117 0.163 526 77 0.146 0
MAD2L1 MAD2L1 Q13257 Mitotic spindle assembly checkpoint protein MAD2A chr4 GO:0009967 Not Cancer Driver No 26 0.127 12 1 0.083 0
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0009967 Not Cancer Driver No 21 0.137 0 0 0.0 0
MAOA MAOA P21397 Amine oxidase [flavin-containing] A chrX GO:0009967 Not Cancer Driver No 61 0.116 23 4 0.174 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0009967 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0009967 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0009967 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0009967 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0009967 Census Yes 157 0.163 593 91 0.153 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0009967 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K3_ENST00000361733 MAP3K3 Q99759 Mitogen-activated protein kinase kinase kinase 3 chr17 GO:0009967 Not Cancer Driver No 74 0.118 355 44 0.124 0
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0009967 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0009967 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0009967 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0009967 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0009967 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPRE2 MAPRE2 Q15555 Microtubule-associated protein RP/EB family member 2 chr18 GO:0009967 Not Cancer Driver No 50 0.153 176 28 0.159 3
MAVS MAVS Q7Z434 Mitochondrial antiviral-signaling protein chr20 GO:0009967 Not Cancer Driver No 70 0.13 411 58 0.141 0
MAZ_ENST00000322945 MAZ P56270 Myc-associated zinc finger protein chr16 GO:0009967 Not Cancer Driver No 46 0.096 249 22 0.088 0
MBD5 MBD5 Q9P267 Methyl-CpG-binding domain protein 5 chr2 GO:0009967 Not Cancer Driver No 254 0.17 1289 219 0.17 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0009967 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCF2L_ENST00000375608 MCF2L O15068 Guanine nucleotide exchange factor DBS chr13 GO:0009967 Not Cancer Driver No 173 0.152 410 54 0.132 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0009967 Not Cancer Driver No 30 0.086 203 21 0.103 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0009967 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEN1 MEN1 O00255 Menin chr11 GO:0009967 Census, Compendium Yes 73 0.119 228 15 0.066 90
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0009967 Not Cancer Driver No 8 0.03 247 7 0.028 0
MFHAS1 MFHAS1 Q9Y4C4 Malignant fibrous histiocytoma-amplified sequence 1 chr8 GO:0009967 Not Cancer Driver No 95 0.09 98 9 0.092 0
MFNG MFNG O00587 Beta-1,3-N-acetylglucosaminyltransferase manic fringe chr22 GO:0009967 Not Cancer Driver No 37 0.115 29 4 0.138 0
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0009967 Not Cancer Driver No 4 0.035 0 0 0.0 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0009967 Not Cancer Driver No 113 0.085 740 56 0.076 0
MIOS_ENST00000405785 MIOS Q9NXC5 GATOR complex protein MIOS chr7 GO:0009967 Not Cancer Driver No 98 0.112 72 4 0.056 0
MLLT3 MLLT3 P42568 Protein AF-9 chr9 GO:0009967 Census, Compendium Yes 69 0.121 414 58 0.14 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0009967 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0009967 Not Cancer Driver No 129 0.182 124 26 0.21 0
MN1 MN1 Q10571 Transcriptional activator MN1 chr22 GO:0009967 Census Yes 148 0.112 1283 140 0.109 0
MRAP MRAP Q8TCY5 Melanocortin-2 receptor accessory protein chr21 GO:0009967 Not Cancer Driver No 29 0.169 63 7 0.111 0
MRAP2 MRAP2 Q96G30 Melanocortin-2 receptor accessory protein 2 chr6 GO:0009967 Not Cancer Driver No 55 0.268 75 17 0.227 0
MSTN MSTN O14793 Growth/differentiation factor 8 chr2 GO:0009967 Not Cancer Driver No 68 0.181 64 11 0.172 0
MSX1 MSX1 P28360 Homeobox protein MSX-1 chr4 GO:0009967 Not Cancer Driver No 39 0.129 197 16 0.081 7
MSX2 MSX2 P35548 Homeobox protein MSX-2 chr5 GO:0009967 Not Cancer Driver No 27 0.101 168 14 0.083 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0009967 Not Cancer Driver No 7 0.103 0 0 0.0 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0009967 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0009967 Not Cancer Driver No 23 0.133 26 4 0.154 0
MYO1C MYO1C O00159 Unconventional myosin-Ic chr17 GO:0009967 Not Cancer Driver No 110 0.103 66 11 0.167 0
MYOC MYOC Q99972 Myocilin chr1 GO:0009967 Not Cancer Driver No 92 0.183 196 43 0.219 58
MYOCD_ENST00000343344 MYOCD Q8IZQ8 Myocardin chr17 GO:0009967 Not Cancer Driver No 284 0.303 853 263 0.308 0
MYORG MYORG Q6NSJ0 Myogenesis-regulating glycosidase chr9 GO:0009967 Not Cancer Driver No 88 0.123 60 3 0.05 2
NACC2_ENST00000371753 NACC2 Q96BF6 Nucleus accumbens-associated protein 2 chr9 GO:0009967 Not Cancer Driver No 24 0.041 238 10 0.042 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0009967 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCK1_ENST00000288986 NCK1 P16333 Cytoplasmic protein NCK1 chr3 GO:0009967 Not Cancer Driver No 48 0.127 111 17 0.153 0
NCK2_ENST00000393349 NCK2 O43639 Cytoplasmic protein NCK2 chr2 GO:0009967 Not Cancer Driver No 89 0.234 88 19 0.216 0
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0009967 Not Cancer Driver No 247 0.219 51 10 0.196 4
NDC80 NDC80 O14777 Kinetochore protein NDC80 homolog chr18 GO:0009967 Not Cancer Driver No 80 0.125 313 45 0.144 0
NDST1 NDST1 P52848 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1 chr5 GO:0009967 Not Cancer Driver No 117 0.133 22 1 0.045 4
NECAB2 NECAB2 Q7Z6G3 N-terminal EF-hand calcium-binding protein 2 chr16 GO:0009967 Not Cancer Driver No 46 0.119 122 9 0.074 0
NECTIN2 NECTIN2 Q92692 Nectin-2 chr19 GO:0009967 Not Cancer Driver No 63 0.117 296 29 0.098 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0009967 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEO1_ENST00000261908 NEO1 Q92859 Neogenin chr15 GO:0009967 Not Cancer Driver No 182 0.125 706 96 0.136 0
NEPRO NEPRO Q6NW34 Nucleolus and neural progenitor protein chr3 GO:0009967 Not Cancer Driver No 62 0.109 147 28 0.19 0
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0009967 Not Cancer Driver No 60 0.101 294 37 0.126 0
NETO1 NETO1 Q8TDF5 Neuropilin and tolloid-like protein 1 chr18 GO:0009967 Not Cancer Driver No 186 0.349 103 33 0.32 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0009967 Not Cancer Driver No 62 0.108 153 11 0.072 0
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0009967 Not Cancer Driver No 26 0.068 210 14 0.067 2
NF1 NF1 P21359 Neurofibromin chr17 GO:0009967 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFAM1 NFAM1 Q8NET5 NFAT activation molecule 1 chr22 GO:0009967 Not Cancer Driver No 30 0.111 116 18 0.155 0
NINJ1 NINJ1 Q92982 Ninjurin-1 chr9 GO:0009967 Not Cancer Driver No 17 0.112 29 0 0.0 0
NKD1 NKD1 Q969G9 Protein naked cuticle homolog 1 chr16 GO:0009967 Not Cancer Driver No 72 0.153 436 67 0.154 0
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0009967 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0009967 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0009967 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0009967 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLRC5_ENST00000436936 NLRC5 Q86WI3 Protein NLRC5 chr16 GO:0009967 Not Cancer Driver No 262 0.14 114 19 0.167 0
NOD2 NOD2 Q9HC29 Nucleotide-binding oligomerization domain-containing protein 2 chr16 GO:0009967 Not Cancer Driver No 169 0.163 40 4 0.1 15
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0009967 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOS1AP NOS1AP O75052 Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein chr1 GO:0009967 Not Cancer Driver No 94 0.186 255 53 0.208 1
NOS3 NOS3 P29474 Nitric oxide synthase, endothelial chr7 GO:0009967 Not Cancer Driver No 168 0.14 347 38 0.11 0
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0009967 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0009967 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOTCH2NLA NOTCH2NLA Q7Z3S9 Notch homolog 2 N-terminal-like protein A chr1 GO:0009967 Not Cancer Driver No 68 0.288 17 2 0.118 0
NOX1 NOX1 Q9Y5S8 NADPH oxidase 1 chrX GO:0009967 Not Cancer Driver No 101 0.179 18 8 0.444 0
NPNT_ENST00000379987 NPNT Q6UXI9 Nephronectin chr4 GO:0009967 Not Cancer Driver No 90 0.159 218 33 0.151 0
NPPC NPPC P23582 C-type natriuretic peptide chr2 GO:0009967 Not Cancer Driver No 10 0.079 82 6 0.073 0
NPR1 NPR1 P16066 Atrial natriuretic peptide receptor 1 chr1 GO:0009967 Not Cancer Driver No 141 0.133 78 16 0.205 0
NPR2 NPR2 P20594 Atrial natriuretic peptide receptor 2 chr9 GO:0009967 Not Cancer Driver No 144 0.138 89 18 0.202 20
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0009967 Not Cancer Driver No 47 0.118 118 9 0.076 0
NR1H3_ENST00000467728 NR1H3 Q13133 Oxysterols receptor LXR-alpha chr11 GO:0009967 Not Cancer Driver No 56 0.125 146 13 0.089 0
NR1H4 NR1H4 Q96RI1 Bile acid receptor chr12 GO:0009967 Not Cancer Driver No 111 0.228 78 18 0.231 0
NR2C1 NR2C1 P13056 Nuclear receptor subfamily 2 group C member 1 chr12 GO:0009967 Not Cancer Driver No 65 0.108 156 13 0.083 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0009967 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0009967 Compendium Yes 146 0.158 211 31 0.147 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0009967 Not Cancer Driver No 593 0.401 301 110 0.365 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0009967 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0009967 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTRK3_ENST00000629765 NTRK3 Q16288 NT-3 growth factor receptor chr15 GO:0009967 Census, Compendium Yes 249 0.297 57 21 0.368 0
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0009967 Not Cancer Driver No 30 0.123 243 30 0.123 0
NUMA1 NUMA1 Q14980 Nuclear mitotic apparatus protein 1 chr11 GO:0009967 Census, Compendium Yes 234 0.111 1864 203 0.109 0
NUP62 NUP62 P37198 Nuclear pore glycoprotein p62 chr19 GO:0009967 Not Cancer Driver No 76 0.146 377 56 0.149 1
NUP93 NUP93 Q8N1F7 Nuclear pore complex protein Nup93 chr16 GO:0009967 Not Cancer Driver No 97 0.118 158 23 0.146 3
NUPR1_ENST00000324873 NUPR1 O60356 Nuclear protein 1 chr16 GO:0009967 Not Cancer Driver No 10 0.122 82 10 0.122 0
OASL OASL Q15646 2'-5'-oligoadenylate synthase-like protein chr12 GO:0009967 Not Cancer Driver No 76 0.148 8 4 0.5 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0009967 Not Cancer Driver No 117 0.308 18 5 0.278 0
OR51E2_ENST00000641638 OR51E2 Q9H255 Olfactory receptor 51E2 chr11 GO:0009967 Not Cancer Driver No 108 0.338 0 0 0.0 0
OSBPL8 OSBPL8 Q9BZF1 Oxysterol-binding protein-related protein 8 chr12 GO:0009967 Not Cancer Driver No 105 0.118 401 37 0.092 0
OSM OSM P13725 Oncostatin-M chr22 GO:0009967 Not Cancer Driver No 43 0.171 114 24 0.211 0
OTUD5 OTUD5 Q96G74 OTU domain-containing protein 5 chrX GO:0009967 Not Cancer Driver No 55 0.096 430 39 0.091 4
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0009967 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0009967 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0009967 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RX5 P2RX5 Q93086 P2X purinoceptor 5 chr17 GO:0009967 Not Cancer Driver No 58 0.137 73 14 0.192 0
P2RY10 P2RY10 O00398 Putative P2Y purinoceptor 10 chrX GO:0009967 Not Cancer Driver No 113 0.333 0 0 0.0 0
P2RY6_ENST00000540342 P2RY6 Q15077 P2Y purinoceptor 6 chr11 GO:0009967 Not Cancer Driver No 50 0.152 10 5 0.5 0
P2RY8 P2RY8 Q86VZ1 P2Y purinoceptor 8 chrX GO:0009967 Census, Compendium Yes 126 0.351 23 5 0.217 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0009967 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAGR1 PAGR1 Q9BTK6 PAXIP1-associated glutamate-rich protein 1 chr16 GO:0009967 Not Cancer Driver No 16 0.063 254 16 0.063 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0009967 Not Cancer Driver No 57 0.105 299 30 0.1 2
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0009967 Not Cancer Driver No 11 0.058 30 0 0.0 5
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0009967 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP14 PARP14 Q460N5 Protein mono-ADP-ribosyltransferase PARP14 chr3 GO:0009967 Not Cancer Driver No 221 0.123 301 57 0.189 0
PARP9 PARP9 Q8IXQ6 Protein mono-ADP-ribosyltransferase PARP9 chr3 GO:0009967 Not Cancer Driver No 110 0.129 45 3 0.067 0
PCID2_ENST00000375479 PCID2 Q5JVF3 PCI domain-containing protein 2 chr13 GO:0009967 Not Cancer Driver No 46 0.115 13 5 0.385 0
PDCD10_ENST00000473645 PDCD10 Q9BUL8 Programmed cell death protein 10 chr3 GO:0009967 Not Cancer Driver No 32 0.151 25 4 0.16 0
PDCL PDCL Q13371 Phosducin-like protein chr9 GO:0009967 Not Cancer Driver No 33 0.11 146 13 0.089 0
PDE6G PDE6G P18545 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr17 GO:0009967 Not Cancer Driver No 15 0.172 58 11 0.19 0
PDE6H PDE6H Q13956 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma chr12 GO:0009967 Not Cancer Driver No 15 0.181 59 14 0.237 0
PDGFA PDGFA P04085 Platelet-derived growth factor subunit A chr7 GO:0009967 Not Cancer Driver No 31 0.147 75 10 0.133 0
PDGFB PDGFB P01127 Platelet-derived growth factor subunit B chr22 GO:0009967 Census Yes 37 0.154 99 22 0.222 2
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0009967 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDGFD PDGFD Q9GZP0 Platelet-derived growth factor D chr11 GO:0009967 Not Cancer Driver No 85 0.23 37 13 0.351 0
PDGFRA PDGFRA P16234 Platelet-derived growth factor receptor alpha chr4 GO:0009967 Census, Compendium Yes 290 0.266 173 45 0.26 2
PDGFRB PDGFRB P09619 Platelet-derived growth factor receptor beta chr5 GO:0009967 Census, Compendium Yes 164 0.148 231 44 0.19 7
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0009967 Not Cancer Driver No 12 0.092 35 5 0.143 0
PELI1 PELI1 Q96FA3 E3 ubiquitin-protein ligase pellino homolog 1 chr2 GO:0009967 Not Cancer Driver No 47 0.112 167 17 0.102 0
PELO PELO Q9BRX2 Protein pelota homolog chr5 GO:0009967 Not Cancer Driver No 38 0.099 67 10 0.149 0
PHB_ENST00000300408 PHB1 P35232 Prohibitin 1 chr17 GO:0009967 Not Cancer Driver No 37 0.136 4 1 0.25 0
PHIP PHIP Q8WWQ0 PH-interacting protein chr6 GO:0009967 Not Cancer Driver No 239 0.131 835 110 0.132 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0009967 Not Cancer Driver No 58 0.114 142 23 0.162 0
PIH1D1 PIH1D1 Q9NWS0 PIH1 domain-containing protein 1 chr19 GO:0009967 Not Cancer Driver No 30 0.103 157 13 0.083 0
PIK3AP1 PIK3AP1 Q6ZUJ8 Phosphoinositide 3-kinase adapter protein 1 chr10 GO:0009967 Not Cancer Driver No 141 0.175 406 81 0.2 0
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0009967 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0009967 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0009967 Census, Compendium Yes 154 0.213 268 61 0.228 2
PIP4P1_ENST00000250489 PIP4P1 Q86T03 Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase chr14 GO:0009967 Not Cancer Driver No 36 0.13 78 4 0.051 0
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0009967 Not Cancer Driver No 80 0.113 598 66 0.11 0
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0009967 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0009967 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLA2R1 PLA2R1 Q13018 Secretory phospholipase A2 receptor chr2 GO:0009967 Not Cancer Driver No 202 0.138 39 2 0.051 0
PLAGL2 PLAGL2 Q9UPG8 Zinc finger protein PLAGL2 chr20 GO:0009967 Not Cancer Driver No 62 0.125 204 29 0.142 0
PLAUR PLAUR Q03405 Urokinase plasminogen activator surface receptor chr19 GO:0009967 Not Cancer Driver No 49 0.146 18 5 0.278 0
PLCG2 PLCG2 P16885 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 chr16 GO:0009967 Not Cancer Driver No 248 0.196 142 30 0.211 1
PLEKHA4 PLEKHA4 Q9H4M7 Pleckstrin homology domain-containing family A member 4 chr19 GO:0009967 Not Cancer Driver No 136 0.175 687 128 0.186 0
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:0009967 Not Cancer Driver No 30 0.108 65 10 0.154 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:0009967 Not Cancer Driver No 228 0.107 684 67 0.098 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0009967 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0009967 Census, Compendium Yes 112 0.127 312 34 0.109 0
POGLUT1 POGLUT1 Q8NBL1 Protein O-glucosyltransferase 1 chr3 GO:0009967 Not Cancer Driver No 57 0.145 0 0 0.0 3
POMC POMC P01189 Pro-opiomelanocortin chr2 GO:0009967 Not Cancer Driver No 50 0.187 198 38 0.192 0
POR POR P16435 NADPH--cytochrome P450 reductase chr7 GO:0009967 Not Cancer Driver No 62 0.092 93 4 0.043 9
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0009967 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPARG PPARG P37231 Peroxisome proliferator-activated receptor gamma chr3 GO:0009967 Census Yes 72 0.143 44 4 0.091 3
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0009967 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0009967 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:0009967 Not Cancer Driver No 72 0.12 17 1 0.059 0
PPP2R5B PPP2R5B Q15173 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform chr11 GO:0009967 Not Cancer Driver No 79 0.159 119 9 0.076 0
PRAG1_ENST00000622241 PRAG1 Q86YV5 Inactive tyrosine-protein kinase PRAG1 chr8 GO:0009967 Not Cancer Driver No 193 0.137 988 150 0.152 0
PRKCA PRKCA P17252 Protein kinase C alpha type chr17 GO:0009967 Not Cancer Driver No 94 0.14 154 22 0.143 0
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0009967 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCH PRKCH P24723 Protein kinase C eta type chr14 GO:0009967 Not Cancer Driver No 89 0.13 92 13 0.141 0
PRKCI PRKCI P41743 Protein kinase C iota type chr3 GO:0009967 Not Cancer Driver No 110 0.185 120 16 0.133 0
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0009967 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKD2_ENST00000291281 PRKD2 Q9BZL6 Serine/threonine-protein kinase D2 chr19 GO:0009967 Compendium Yes 118 0.134 246 34 0.138 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0009967 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRKRA PRKRA O75569 Interferon-inducible double-stranded RNA-dependent protein kinase activator A chr2 GO:0009967 Not Cancer Driver No 41 0.131 104 12 0.115 1
PRMT1 PRMT1 Q99873 Protein arginine N-methyltransferase 1 chr19 GO:0009967 Not Cancer Driver No 50 0.135 18 1 0.056 0
PRMT5 PRMT5 O14744 Protein arginine N-methyltransferase 5 chr14 GO:0009967 Not Cancer Driver No 83 0.13 72 6 0.083 0
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0009967 Not Cancer Driver No 182 0.247 537 141 0.263 0
PRR5L PRR5L Q6MZQ0 Proline-rich protein 5-like chr11 GO:0009967 Not Cancer Driver No 57 0.155 108 12 0.111 0
PRR5_ENST00000336985 PRR5 P85299 Proline-rich protein 5 chr22 GO:0009967 Not Cancer Driver No 50 0.129 173 22 0.127 0
PRRX1 PRRX1 P54821 Paired mesoderm homeobox protein 1 chr1 GO:0009967 Census, Compendium Yes 69 0.282 205 49 0.239 1
PTBP1_ENST00000349038 PTBP1 P26599 Polypyrimidine tract-binding protein 1 chr19 GO:0009967 Not Cancer Driver No 74 0.139 154 17 0.11 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0009967 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGDR2 PTGDR2 Q9Y5Y4 Prostaglandin D2 receptor 2 chr11 GO:0009967 Not Cancer Driver No 23 0.058 39 0 0.0 0
PTGIS PTGIS Q16647 Prostacyclin synthase chr20 GO:0009967 Not Cancer Driver No 102 0.204 18 3 0.167 0
PTH PTH P01270 Parathyroid hormone chr11 GO:0009967 Not Cancer Driver No 19 0.165 60 10 0.167 2
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0009967 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTK2_ENST00000522684 PTK2 Q05397 Focal adhesion kinase 1 chr8 GO:0009967 Not Cancer Driver No 134 0.127 425 55 0.129 0
PTK6 PTK6 Q13882 Protein-tyrosine kinase 6 chr20 GO:0009967 Census Yes 42 0.093 12 0 0.0 0
PTPN1 PTPN1 P18031 Tyrosine-protein phosphatase non-receptor type 1 chr20 GO:0009967 Not Cancer Driver No 49 0.113 140 25 0.179 0
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0009967 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0009967 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPN22 PTPN22 Q9Y2R2 Tyrosine-protein phosphatase non-receptor type 22 chr1 GO:0009967 Not Cancer Driver No 141 0.175 364 62 0.17 4
PTPN6_ENST00000318974 PTPN6 P29350 Tyrosine-protein phosphatase non-receptor type 6 chr12 GO:0009967 Census, Compendium Yes 73 0.123 192 25 0.13 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0009967 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRJ PTPRJ Q12913 Receptor-type tyrosine-protein phosphatase eta chr11 GO:0009967 Not Cancer Driver No 184 0.138 401 61 0.152 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0009967 Not Cancer Driver No 150 0.126 640 77 0.12 3
PUM2_ENST00000403432 PUM2 Q8TB72 Pumilio homolog 2 chr2 GO:0009967 Not Cancer Driver No 132 0.124 575 83 0.144 0
PYHIN1 PYHIN1 Q6K0P9 Pyrin and HIN domain-containing protein 1 chr1 GO:0009967 Not Cancer Driver No 174 0.354 291 99 0.34 0
RAB29 RAB29 O14966 Ras-related protein Rab-7L1 chr1 GO:0009967 Not Cancer Driver No 28 0.138 18 3 0.167 0
RAB34_ENST00000436730 RAB34 Q9BZG1 Ras-related protein Rab-34 chr17 GO:0009967 Not Cancer Driver No 41 0.158 1 0 0.0 0
RAC1_ENST00000348035 RAC1 P63000 Ras-related C3 botulinum toxin substrate 1 chr7 GO:0009967 Census, Compendium Yes 66 0.344 2 1 0.5 6
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0009967 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0009967 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAMP3 RAMP3 O60896 Receptor activity-modifying protein 3 chr7 GO:0009967 Not Cancer Driver No 30 0.203 0 0 0.0 0
RAPGEF2 RAPGEF2 Q9Y4G8 Rap guanine nucleotide exchange factor 2 chr4 GO:0009967 Not Cancer Driver No 216 0.144 803 116 0.144 0
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0009967 Not Cancer Driver No 49 0.098 151 19 0.126 2
RBPMS_ENST00000320203 RBPMS Q93062 RNA-binding protein with multiple splicing chr8 GO:0009967 Not Cancer Driver No 23 0.117 87 11 0.126 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0009967 Compendium Yes 75 0.136 400 48 0.12 0
RELL1_ENST00000314117 RELL1 Q8IUW5 RELT-like protein 1 chr4 GO:0009967 Not Cancer Driver No 19 0.07 201 11 0.055 0
RELL2 RELL2 Q8NC24 RELT-like protein 2 chr5 GO:0009967 Not Cancer Driver No 39 0.129 259 37 0.143 0
RELN RELN P78509 Reelin chr7 GO:0009967 Not Cancer Driver No 761 0.22 107 19 0.178 7
RET RET P07949 Proto-oncogene tyrosine-protein kinase receptor Ret chr10 GO:0009967 Census, Compendium Yes 208 0.187 105 12 0.114 139
RFNG RFNG Q9Y644 Beta-1,3-N-acetylglucosaminyltransferase radical fringe chr17 GO:0009967 Not Cancer Driver No 22 0.066 92 5 0.054 0
RGL2 RGL2 O15211 Ral guanine nucleotide dissociation stimulator-like 2 chr6 GO:0009967 Not Cancer Driver No 87 0.112 461 51 0.111 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0009967 Not Cancer Driver No 68 0.332 5 4 0.8 0
RIMS1 RIMS1 Q86UR5 Regulating synaptic membrane exocytosis protein 1 chr6 GO:0009967 Not Cancer Driver No 403 0.238 1315 306 0.233 1
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0009967 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0009967 Not Cancer Driver No 63 0.117 143 20 0.14 0
RIPK3 RIPK3 Q9Y572 Receptor-interacting serine/threonine-protein kinase 3 chr14 GO:0009967 Not Cancer Driver No 66 0.127 295 39 0.132 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0009967 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF165 RNF165 Q6ZSG1 E3 ubiquitin-protein ligase RNF165 chr18 GO:0009967 Not Cancer Driver No 62 0.179 225 40 0.178 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0009967 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF185 RNF185 Q96GF1 E3 ubiquitin-protein ligase RNF185 chr22 GO:0009967 Not Cancer Driver No 25 0.13 82 15 0.183 0
ROBO1 ROBO1 Q9Y6N7 Roundabout homolog 1 chr3 GO:0009967 Not Cancer Driver No 353 0.214 1122 234 0.209 0
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0009967 Census Yes 407 0.295 874 259 0.296 2
ROR1 ROR1 Q01973 Inactive tyrosine-protein kinase transmembrane receptor ROR1 chr1 GO:0009967 Not Cancer Driver No 144 0.154 280 43 0.154 1
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0009967 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPL23_ENST00000394332 RPL23 P62829 60S ribosomal protein L23 chr17 GO:0009967 Not Cancer Driver No 14 0.1 29 4 0.138 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0009967 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPL37 RPL37 P61927 60S ribosomal protein L37 chr5 GO:0009967 Not Cancer Driver No 12 0.124 83 10 0.12 0
RPS15_ENST00000592588 RPS15 P62841 40S ribosomal protein S15 chr19 GO:0009967 Not Cancer Driver No 13 0.09 59 7 0.119 0
RPS20_ENST00000521262 RPS20 P60866 40S ribosomal protein S20 chr8 GO:0009967 Not Cancer Driver No 18 0.151 53 8 0.151 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0009967 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS7_ENST00000645674 RPS7 P62081 40S ribosomal protein S7 chr2 GO:0009967 Not Cancer Driver No 29 0.149 39 7 0.179 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0009967 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGB RRAGB Q5VZM2 Ras-related GTP-binding protein B chrX GO:0009967 Not Cancer Driver No 67 0.179 37 5 0.135 0
RRAGD RRAGD Q9NQL2 Ras-related GTP-binding protein D chr6 GO:0009967 Not Cancer Driver No 42 0.105 83 5 0.06 0
RSAD2 RSAD2 Q8WXG1 Radical S-adenosyl methionine domain-containing protein 2 chr2 GO:0009967 Not Cancer Driver No 68 0.188 22 1 0.045 0
RSPO3 RSPO3 Q9BXY4 R-spondin-3 chr6 GO:0009967 Census Yes 44 0.162 100 12 0.12 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0009967 Not Cancer Driver No 121 0.102 866 82 0.095 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0009967 Not Cancer Driver No 38 0.08 148 17 0.115 5
RUNDC3A RUNDC3A Q59EK9 RUN domain-containing protein 3A chr17 GO:0009967 Not Cancer Driver No 39 0.087 175 8 0.046 0
RWDD3 RWDD3 Q9Y3V2 RWD domain-containing protein 3 chr1 GO:0009967 Not Cancer Driver No 40 0.15 12 4 0.333 0
RXRA RXRA P19793 Retinoic acid receptor RXR-alpha chr9 GO:0009967 Compendium Yes 90 0.195 184 26 0.141 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0009967 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0009967 Not Cancer Driver No 18 0.158 76 7 0.092 0
SASH1 SASH1 O94885 SAM and SH3 domain-containing protein 1 chr6 GO:0009967 Not Cancer Driver No 174 0.14 1071 153 0.143 7
SCIMP SCIMP Q6UWF3 SLP adapter and CSK-interacting membrane protein chr17 GO:0009967 Not Cancer Driver No 10 0.069 73 9 0.123 0
SCT SCT P09683 Secretin chr11 GO:0009967 Not Cancer Driver No 4 0.033 71 3 0.042 0
SCTR SCTR P47872 Secretin receptor chr2 GO:0009967 Not Cancer Driver No 74 0.168 18 1 0.056 0
SCUBE1 SCUBE1 Q8IWY4 Signal peptide, CUB and EGF-like domain-containing protein 1 chr22 GO:0009967 Not Cancer Driver No 149 0.151 97 21 0.216 0
SCUBE3 SCUBE3 Q8IX30 Signal peptide, CUB and EGF-like domain-containing protein 3 chr6 GO:0009967 Not Cancer Driver No 131 0.132 110 17 0.155 2
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0009967 Not Cancer Driver No 39 0.131 17 2 0.118 0
SEH1L_ENST00000262124 SEH1L Q96EE3 Nucleoporin SEH1 chr18 GO:0009967 Not Cancer Driver No 40 0.111 71 11 0.155 0
SELP SELP P16109 P-selectin chr1 GO:0009967 Not Cancer Driver No 226 0.272 14 2 0.143 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0009967 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0009967 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERINC3_ENST00000255175 SERINC3 Q13530 Serine incorporator 3 chr20 GO:0009967 Not Cancer Driver No 73 0.154 38 9 0.237 0
SERPINA12 SERPINA12 Q8IW75 Serpin A12 chr14 GO:0009967 Not Cancer Driver No 90 0.217 22 3 0.136 0
SFPQ SFPQ P23246 Splicing factor, proline- and glutamine-rich chr1 GO:0009967 Census Yes 59 0.083 595 48 0.081 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0009967 Not Cancer Driver No 40 0.127 39 7 0.179 0
SH2B1 SH2B1 Q9NRF2 SH2B adapter protein 1 chr16 GO:0009967 Not Cancer Driver No 98 0.13 612 84 0.137 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0009967 Not Cancer Driver No 288 0.133 1659 186 0.112 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0009967 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHKBP1 SHKBP1 Q8TBC3 SH3KBP1-binding protein 1 chr19 GO:0009967 Not Cancer Driver No 93 0.132 281 32 0.114 0
SHOX2_ENST00000441443 SHOX2 O60902 Short stature homeobox protein 2 chr3 GO:0009967 Not Cancer Driver No 67 0.202 200 40 0.2 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0009967 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIK3 SIK3 Q9Y2K2 Serine/threonine-protein kinase SIK3 chr11 GO:0009967 Not Cancer Driver No 143 0.108 964 107 0.111 1
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0009967 Not Cancer Driver No 70 0.094 435 31 0.071 0
SKIL_ENST00000259119 SKIL P12757 Ski-like protein chr3 GO:0009967 Not Cancer Driver No 77 0.113 356 32 0.09 0
SKP2 SKP2 Q13309 S-phase kinase-associated protein 2 chr5 GO:0009967 Not Cancer Driver No 52 0.123 52 6 0.115 0
SLC15A3 SLC15A3 Q8IY34 Solute carrier family 15 member 3 chr11 GO:0009967 Not Cancer Driver No 63 0.108 43 1 0.023 0
SLC15A4 SLC15A4 Q8N697 Solute carrier family 15 member 4 chr12 GO:0009967 Not Cancer Driver No 66 0.114 23 4 0.174 0
SLC2A10 SLC2A10 O95528 Solute carrier family 2, facilitated glucose transporter member 10 chr20 GO:0009967 Not Cancer Driver No 98 0.181 72 15 0.208 8
SLC2A4 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0009967 Not Cancer Driver No 71 0.139 43 8 0.186 1
SLC35C2_ENST00000372227 SLC35C2 Q9NQQ7 Solute carrier family 35 member C2 chr20 GO:0009967 Not Cancer Driver No 56 0.153 15 2 0.133 0
SLC39A10_ENST00000359634 SLC39A10 Q9ULF5 Zinc transporter ZIP10 chr2 GO:0009967 Not Cancer Driver No 111 0.134 417 63 0.151 0
SLC39A14_ENST00000381237 SLC39A14 Q15043 Metal cation symporter ZIP14 chr8 GO:0009967 Not Cancer Driver No 34 0.069 42 3 0.071 4
SLC46A2 SLC46A2 Q9BY10 Thymic stromal cotransporter homolog chr9 GO:0009967 Not Cancer Driver No 45 0.095 36 3 0.083 0
SLC9A1 SLC9A1 P19634 Sodium/hydrogen exchanger 1 chr1 GO:0009967 Not Cancer Driver No 89 0.109 251 29 0.116 1
SLC9A3R1 SLC9A3R1 O14745 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 chr17 GO:0009967 Not Cancer Driver No 19 0.053 318 16 0.05 4
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0009967 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0009967 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0009967 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCB1_ENST00000644036 SMARCB1 Q12824 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 chr22 GO:0009967 Census, Compendium Yes 64 0.166 141 35 0.248 3
SMO SMO Q99835 Smoothened homolog chr7 GO:0009967 Census, Compendium Yes 112 0.142 241 27 0.112 1
SMOC2_ENST00000356284 SMOC2 Q9H3U7 SPARC-related modular calcium-binding protein 2 chr6 GO:0009967 Not Cancer Driver No 82 0.184 216 52 0.241 0
SNW1_ENST00000261531 SNW1 Q13573 SNW domain-containing protein 1 chr14 GO:0009967 Not Cancer Driver No 62 0.116 488 56 0.115 0
SNX5_ENST00000377759 SNX5 Q9Y5X3 Sorting nexin-5 chr20 GO:0009967 Not Cancer Driver No 33 0.082 91 13 0.143 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0009967 Not Cancer Driver No 16 0.104 93 9 0.097 79
SORBS1_ENST00000361941 SORBS1 Q9BX66 Sorbin and SH3 domain-containing protein 1 chr10 GO:0009967 Not Cancer Driver No 161 0.125 1111 133 0.12 0
SORL1 SORL1 Q92673 Sortilin-related receptor chr11 GO:0009967 Not Cancer Driver No 374 0.169 87 10 0.115 0
SOS1_ENST00000402219 SOS1 Q07889 Son of sevenless homolog 1 chr2 GO:0009967 Compendium Yes 197 0.148 458 62 0.135 38
SOS2 SOS2 Q07890 Son of sevenless homolog 2 chr14 GO:0009967 Not Cancer Driver No 173 0.13 362 54 0.149 2
SOX11 SOX11 P35716 Transcription factor SOX-11 chr2 GO:0009967 Not Cancer Driver No 61 0.138 368 53 0.144 2
SOX9 SOX9 P48436 Transcription factor SOX-9 chr17 GO:0009967 Compendium Yes 86 0.169 495 82 0.166 18
SPATC1L SPATC1L Q9H0A9 Speriolin-like protein chr21 GO:0009967 Not Cancer Driver No 30 0.088 179 11 0.061 0
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0009967 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0009967 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0009967 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPPL3 SPPL3 Q8TCT6 Signal peptide peptidase-like 3 chr12 GO:0009967 Not Cancer Driver No 45 0.117 23 0 0.0 0
SPRED1 SPRED1 Q7Z699 Sprouty-related, EVH1 domain-containing protein 1 chr15 GO:0009967 Not Cancer Driver No 71 0.16 194 35 0.18 2
SPRED2 SPRED2 Q7Z698 Sprouty-related, EVH1 domain-containing protein 2 chr2 GO:0009967 Not Cancer Driver No 73 0.175 228 43 0.189 0
SRARP SRARP Q8NEQ6 Steroid receptor-associated and regulated protein chr1 GO:0009967 Not Cancer Driver No 19 0.112 90 9 0.1 0
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0009967 Census Yes 53 0.099 130 11 0.085 1
SRPX SRPX P78539 Sushi repeat-containing protein SRPX chrX GO:0009967 Not Cancer Driver No 71 0.153 60 10 0.167 0
STAP1_ENST00000396225 STAP1 Q9ULZ2 Signal-transducing adaptor protein 1 chr4 GO:0009967 Not Cancer Driver No 66 0.224 103 18 0.175 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0009967 Census, Compendium Yes 110 0.143 152 15 0.099 19
STIMATE STIMATE Q86TL2 Store-operated calcium entry regulator STIMATE chr3 GO:0009967 Not Cancer Driver No 27 0.092 61 4 0.066 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0009967 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK36_ENST00000440309 STK36 Q9NRP7 Serine/threonine-protein kinase 36 chr2 GO:0009967 Not Cancer Driver No 167 0.127 250 36 0.144 0
STK39 STK39 Q9UEW8 STE20/SPS1-related proline-alanine-rich protein kinase chr2 GO:0009967 Not Cancer Driver No 64 0.117 182 19 0.104 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0009967 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0009967 Not Cancer Driver No 70 0.144 231 30 0.13 0
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0009967 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0009967 Not Cancer Driver No 38 0.132 155 20 0.129 2
STYXL1_ENST00000359697 STYXL1 Q9Y6J8 Serine/threonine/tyrosine-interacting-like protein 1 chr7 GO:0009967 Not Cancer Driver No 55 0.176 18 3 0.167 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0009967 Not Cancer Driver No 246 0.282 269 71 0.264 0
SYK_ENST00000375746 SYK P43405 Tyrosine-protein kinase SYK chr9 GO:0009967 Census Yes 96 0.151 131 27 0.206 5
SYNPO2L SYNPO2L Q9H987 Synaptopodin 2-like protein chr10 GO:0009967 Not Cancer Driver No 103 0.105 950 99 0.104 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0009967 Not Cancer Driver No 123 0.137 494 64 0.13 0
TBK1 TBK1 Q9UHD2 Serine/threonine-protein kinase TBK1 chr12 GO:0009967 Not Cancer Driver No 101 0.139 42 5 0.119 12
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0009967 Not Cancer Driver No 117 0.262 201 54 0.269 2
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0009967 Not Cancer Driver No 21 0.198 33 7 0.212 0
TEDC1_ENST00000392523 TEDC1 Q86SX3 Tubulin epsilon and delta complex protein 1 chr14 GO:0009967 Not Cancer Driver No 25 0.051 160 6 0.037 0
TEDC2 TEDC2 Q7L2K0 Tubulin epsilon and delta complex protein 2 chr16 GO:0009967 Not Cancer Driver No 46 0.106 253 26 0.103 0
TEK TEK Q02763 Angiopoietin-1 receptor chr9 GO:0009967 Not Cancer Driver No 219 0.195 126 22 0.175 10
TELO2 TELO2 Q9Y4R8 Telomere length regulation protein TEL2 homolog chr16 GO:0009967 Not Cancer Driver No 113 0.135 154 23 0.149 5
TESPA1 TESPA1 A2RU30 Protein TESPA1 chr12 GO:0009967 Not Cancer Driver No 127 0.244 284 84 0.296 0
TGFA_ENST00000295400 TGFA P01135 Protransforming growth factor alpha chr2 GO:0009967 Not Cancer Driver No 20 0.125 0 0 0.0 0
TGFB1 TGFB1 P01137 Transforming growth factor beta-1 proprotein chr19 GO:0009967 Not Cancer Driver No 41 0.105 41 4 0.098 10
TGFB1I1 TGFB1I1 O43294 Transforming growth factor beta-1-induced transcript 1 protein chr16 GO:0009967 Not Cancer Driver No 61 0.132 219 34 0.155 0
TGFB2_ENST00000366930 TGFB2 P61812 Transforming growth factor beta-2 proprotein chr1 GO:0009967 Not Cancer Driver No 63 0.152 47 8 0.17 3
TGFB3 TGFB3 P10600 Transforming growth factor beta-3 proprotein chr14 GO:0009967 Not Cancer Driver No 45 0.109 96 14 0.146 1
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0009967 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0009967 Census, Compendium Yes 106 0.187 60 16 0.267 25
TGFBR3_ENST00000525962 TGFBR3 Q03167 Transforming growth factor beta receptor type 3 chr1 GO:0009967 Not Cancer Driver No 129 0.152 268 41 0.153 0
TGM2 TGM2 P21980 Protein-glutamine gamma-glutamyltransferase 2 chr20 GO:0009967 Not Cancer Driver No 123 0.179 107 26 0.243 0
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0009967 Not Cancer Driver No 188 0.161 320 58 0.181 0
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0009967 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIAL1_ENST00000436547 TIAL1 Q01085 Nucleolysin TIAR chr10 GO:0009967 Not Cancer Driver No 45 0.12 122 12 0.098 0
TICAM2 TICAM2 Q86XR7 TIR domain-containing adapter molecule 2 chr5 GO:0009967 Not Cancer Driver No 35 0.149 88 10 0.114 0
TIMP3 TIMP3 P35625 Metalloproteinase inhibitor 3 chr22 GO:0009967 Not Cancer Driver No 43 0.204 3 1 0.333 5
TIRAP_ENST00000392680 TIRAP P58753 Toll/interleukin-1 receptor domain-containing adapter protein chr11 GO:0009967 Not Cancer Driver No 28 0.127 80 6 0.075 0
TLR1_ENST00000502213 TLR1 Q15399 Toll-like receptor 1 chr4 GO:0009967 Not Cancer Driver No 107 0.136 1 0 0.0 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0009967 Not Cancer Driver No 108 0.138 0 0 0.0 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0009967 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR4_ENST00000355622 TLR4 O00206 Toll-like receptor 4 chr9 GO:0009967 Not Cancer Driver No 292 0.348 0 0 0.0 0
TLR5_ENST00000366881 TLR5 O60602 Toll-like receptor 5 chr1 GO:0009967 Not Cancer Driver No 148 0.172 16 3 0.188 0
TLR6 TLR6 Q9Y2C9 Toll-like receptor 6 chr4 GO:0009967 Not Cancer Driver No 99 0.124 1 0 0.0 0
TLR9 TLR9 Q9NR96 Toll-like receptor 9 chr3 GO:0009967 Not Cancer Driver No 141 0.137 35 3 0.086 0
TM2D3 TM2D3 Q9BRN9 TM2 domain-containing protein 3 chr15 GO:0009967 Not Cancer Driver No 31 0.126 13 3 0.231 0
TMEM108 TMEM108 Q6UXF1 Transmembrane protein 108 chr3 GO:0009967 Not Cancer Driver No 101 0.176 458 89 0.194 0
TMEM173 STING1 Q86WV6 Stimulator of interferon genes protein chr5 GO:0009967 Not Cancer Driver No 46 0.121 66 13 0.197 3
TMEM33_ENST00000325094 TMEM33 P57088 Transmembrane protein 33 chr4 GO:0009967 Not Cancer Driver No 24 0.097 6 0 0.0 0
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0009967 Not Cancer Driver No 33 0.094 216 22 0.102 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0009967 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0009967 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNFSF11 TNFSF11 O14788 Tumor necrosis factor ligand superfamily member 11 chr13 GO:0009967 Not Cancer Driver No 52 0.164 56 1 0.018 1
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0009967 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0009967 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPR TPR P12270 Nucleoprotein TPR chr1 GO:0009967 Census Yes 311 0.132 1990 266 0.134 0
TRAF2 TRAF2 Q12933 TNF receptor-associated factor 2 chr9 GO:0009967 Not Cancer Driver No 63 0.126 4 1 0.25 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0009967 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAT1 TRAT1 Q6PIZ9 T-cell receptor-associated transmembrane adapter 1 chr3 GO:0009967 Not Cancer Driver No 86 0.462 129 67 0.519 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0009967 Not Cancer Driver No 43 0.187 27 2 0.074 1
TREML4_ENST00000448827 TREML4 Q6UXN2 Trem-like transcript 4 protein chr6 GO:0009967 Not Cancer Driver No 43 0.215 22 6 0.273 0
TRIM15 TRIM15 Q9C019 Tripartite motif-containing protein 15 chr6 GO:0009967 Not Cancer Driver No 69 0.148 79 11 0.139 0
TRIM16_ENST00000336708 TRIM16 O95361 Tripartite motif-containing protein 16 chr17 GO:0009967 Not Cancer Driver No 64 0.113 132 11 0.083 0
TRIM32 TRIM32 Q13049 E3 ubiquitin-protein ligase TRIM32 chr9 GO:0009967 Not Cancer Driver No 82 0.126 87 10 0.115 3
TRIM41 TRIM41 Q8WV44 E3 ubiquitin-protein ligase TRIM41 chr5 GO:0009967 Not Cancer Driver No 69 0.11 385 38 0.099 0
TRIM44 TRIM44 Q96DX7 Tripartite motif-containing protein 44 chr11 GO:0009967 Not Cancer Driver No 40 0.116 272 33 0.121 1
TRIM56 TRIM56 Q9BRZ2 E3 ubiquitin-protein ligase TRIM56 chr7 GO:0009967 Not Cancer Driver No 110 0.146 217 36 0.166 0
TRIM6_ENST00000278302 TRIM6 Q9C030 Tripartite motif-containing protein 6 chr11 GO:0009967 Not Cancer Driver No 86 0.176 47 15 0.319 0
TSLP TSLP Q969D9 Thymic stromal lymphopoietin chr5 GO:0009967 Not Cancer Driver No 27 0.17 16 0 0.0 0
TSPAN14_ENST00000372156 TSPAN14 Q8NG11 Tetraspanin-14 chr10 GO:0009967 Not Cancer Driver No 38 0.141 0 0 0.0 0
TSPAN5 TSPAN5 P62079 Tetraspanin-5 chr4 GO:0009967 Not Cancer Driver No 49 0.183 0 0 0.0 0
TTC23 TTC23 Q5W5X9 Tetratricopeptide repeat protein 23 chr15 GO:0009967 Not Cancer Driver No 42 0.094 109 13 0.119 0
TTK TTK P33981 Dual specificity protein kinase TTK chr6 GO:0009967 Not Cancer Driver No 136 0.159 352 46 0.131 0
TUBD1_ENST00000592426 TUBD1 Q9UJT1 Tubulin delta chain chr17 GO:0009967 Not Cancer Driver No 54 0.119 3 0 0.0 0
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0009967 Not Cancer Driver No 27 0.121 19 3 0.158 0
TXK TXK P42681 Tyrosine-protein kinase TXK chr4 GO:0009967 Not Cancer Driver No 87 0.165 61 9 0.148 0
TXNDC15 TXNDC15 Q96J42 Thioredoxin domain-containing protein 15 chr5 GO:0009967 Not Cancer Driver No 36 0.1 137 15 0.109 0
UBB_ENST00000614404 UBB P0CG47 Polyubiquitin-B chr17 GO:0009967 Not Cancer Driver No 20 0.087 102 8 0.078 0
UBE2K UBE2K P61086 Ubiquitin-conjugating enzyme E2 K chr4 GO:0009967 Not Cancer Driver No 24 0.12 33 3 0.091 0
UBE2O UBE2O Q9C0C9 (E3-independent) E2 ubiquitin-conjugating enzyme chr17 GO:0009967 Not Cancer Driver No 129 0.1 716 68 0.095 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0009967 Not Cancer Driver No 141 0.161 136 22 0.162 0
UCHL5 UCHL5 Q9Y5K5 Ubiquitin carboxyl-terminal hydrolase isozyme L5 chr1 GO:0009967 Not Cancer Driver No 33 0.1 41 7 0.171 0
UCN UCN P55089 Urocortin chr2 GO:0009967 Not Cancer Driver No 7 0.056 61 4 0.066 0
ULK3 ULK3 Q6PHR2 Serine/threonine-protein kinase ULK3 chr15 GO:0009967 Not Cancer Driver No 37 0.078 55 2 0.036 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0009967 Not Cancer Driver No 155 0.164 117 20 0.171 0
USP15 USP15 Q9Y4E8 Ubiquitin carboxyl-terminal hydrolase 15 chr12 GO:0009967 Not Cancer Driver No 136 0.139 259 39 0.151 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0009967 Not Cancer Driver No 105 0.198 201 54 0.269 0
USP27X USP27X A6NNY8 Ubiquitin carboxyl-terminal hydrolase 27 chrX GO:0009967 Not Cancer Driver No 31 0.071 69 3 0.043 1
USP29_ENST00000598197 USP29 Q9HBJ7 Ubiquitin carboxyl-terminal hydrolase 29 chr19 GO:0009967 Not Cancer Driver No 291 0.316 432 132 0.306 0
VDR_ENST00000549336 VDR P11473 Vitamin D3 receptor chr12 GO:0009967 Not Cancer Driver No 64 0.15 102 16 0.157 14
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0009967 Not Cancer Driver No 27 0.116 41 7 0.171 0
VPS35 VPS35 Q96QK1 Vacuolar protein sorting-associated protein 35 chr16 GO:0009967 Not Cancer Driver No 68 0.085 99 9 0.091 1
VTN VTN P04004 Vitronectin chr17 GO:0009967 Not Cancer Driver No 76 0.159 168 29 0.173 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0009967 Not Cancer Driver No 106 0.164 571 95 0.166 0
WASF1_ENST00000392586 WASF1 Q92558 Wiskott-Aldrich syndrome protein family member 1 chr6 GO:0009967 Not Cancer Driver No 63 0.113 445 49 0.11 0
WBP2_ENST00000254806 WBP2 Q969T9 WW domain-binding protein 2 chr17 GO:0009967 Not Cancer Driver No 26 0.1 102 6 0.059 1
WDFY1 WDFY1 Q8IWB7 WD repeat and FYVE domain-containing protein 1 chr2 GO:0009967 Not Cancer Driver No 51 0.124 24 2 0.083 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0009967 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0009967 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT16 WNT16 Q9UBV4 Protein Wnt-16 chr7 GO:0009967 Not Cancer Driver No 59 0.162 28 9 0.321 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0009967 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0009967 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT5B_ENST00000310594 WNT5B Q9H1J7 Protein Wnt-5b chr12 GO:0009967 Not Cancer Driver No 60 0.167 23 4 0.174 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0009967 Not Cancer Driver No 93 0.266 18 9 0.5 4
WWOX WWOX Q9NZC7 WW domain-containing oxidoreductase chr16 GO:0009967 Not Cancer Driver No 79 0.191 108 9 0.083 3
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0009967 Not Cancer Driver No 19 0.073 169 9 0.053 0
XDH XDH P47989 Xanthine dehydrogenase/oxidase chr2 GO:0009967 Not Cancer Driver No 279 0.209 134 24 0.179 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0009967 Not Cancer Driver No 24 0.069 35 2 0.057 1
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0009967 Not Cancer Driver No 51 0.101 489 49 0.1 0
ZAP70 ZAP70 P43403 Tyrosine-protein kinase ZAP-70 chr2 GO:0009967 Not Cancer Driver No 126 0.204 117 17 0.145 8
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0009967 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0009967 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0009967 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H3 ZC3H3 Q8IXZ2 Zinc finger CCCH domain-containing protein 3 chr8 GO:0009967 Not Cancer Driver No 130 0.137 750 99 0.132 0
ZCCHC3 ZCCHC3 Q9NUD5 Zinc finger CCHC domain-containing protein 3 chr20 GO:0009967 Not Cancer Driver No 28 0.069 160 1 0.006 0
ZDHHC5 ZDHHC5 Q9C0B5 Palmitoyltransferase ZDHHC5 chr11 GO:0009967 Not Cancer Driver No 89 0.124 462 63 0.136 0
ZEB2_ENST00000558170 ZEB2 O60315 Zinc finger E-box-binding homeobox 2 chr2 GO:0009967 Not Cancer Driver No 299 0.246 859 211 0.246 2
ZMIZ1 ZMIZ1 Q9ULJ6 Zinc finger MIZ domain-containing protein 1 chr10 GO:0009967 Not Cancer Driver No 148 0.139 762 111 0.146 5
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0009967 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF423 ZNF423 Q2M1K9 Zinc finger protein 423 chr16 GO:0009967 Not Cancer Driver No 340 0.265 416 108 0.26 2
ZSWIM2 ZSWIM2 Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 chr2 GO:0009967 Not Cancer Driver No 189 0.299 85 30 0.353 0