Total number of protein in "GO:0009755" GO term: 101
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACSL1_ENST00000281455 | ACSL1 | P33121 | Long-chain-fatty-acid--CoA ligase 1 | chr4 | GO:0009755 | Not Cancer Driver | No | 85 | 0.122 | 27 | 1 | 0.037 | 0 |
| ADIPOR1 | ADIPOR1 | Q96A54 | Adiponectin receptor protein 1 | chr1 | GO:0009755 | Not Cancer Driver | No | 63 | 0.168 | 69 | 10 | 0.145 | 0 |
| ADIPOR2 | ADIPOR2 | Q86V24 | Adiponectin receptor protein 2 | chr12 | GO:0009755 | Not Cancer Driver | No | 44 | 0.114 | 82 | 7 | 0.085 | 0 |
| AGRP | AGRP | O00253 | Agouti-related protein | chr16 | GO:0009755 | Not Cancer Driver | No | 13 | 0.098 | 32 | 4 | 0.125 | 0 |
| APPL1 | APPL1 | Q9UKG1 | DCC-interacting protein 13-alpha | chr3 | GO:0009755 | Not Cancer Driver | No | 67 | 0.094 | 292 | 31 | 0.106 | 1 |
| APPL2_ENST00000258530 | APPL2 | Q8NEU8 | DCC-interacting protein 13-beta | chr12 | GO:0009755 | Not Cancer Driver | No | 70 | 0.105 | 149 | 14 | 0.094 | 0 |
| AR | AR | P10275 | Androgen receptor | chrX | GO:0009755 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
| ARID1A | ARID1A | O14497 | AT-rich interactive domain-containing protein 1A | chr1 | GO:0009755 | Census, Compendium | Yes | 275 | 0.12 | 1856 | 206 | 0.111 | 0 |
| ASIP_ENST00000374954 | ASIP | P42127 | Agouti-signaling protein | chr20 | GO:0009755 | Not Cancer Driver | No | 16 | 0.121 | 36 | 9 | 0.25 | 0 |
| CALR | CALR | P27797 | Calreticulin | chr19 | GO:0009755 | Census | Yes | 45 | 0.108 | 245 | 31 | 0.127 | 0 |
| CRHBP | CRHBP | P24387 | Corticotropin-releasing factor-binding protein | chr5 | GO:0009755 | Not Cancer Driver | No | 61 | 0.189 | 0 | 0 | 0.0 | 0 |
| CRHR1 | CRHR1 | P34998 | Corticotropin-releasing factor receptor 1 | chr17 | GO:0009755 | Not Cancer Driver | No | 75 | 0.169 | 0 | 0 | 0.0 | 0 |
| CRHR2_ENST00000471646 | CRHR2 | Q13324 | Corticotropin-releasing factor receptor 2 | chr7 | GO:0009755 | Not Cancer Driver | No | 79 | 0.192 | 0 | 0 | 0.0 | 0 |
| CSNK2B_ENST00000375866 | CSNK2B | P67870 | Casein kinase II subunit beta | chr6 | GO:0009755 | Not Cancer Driver | No | 20 | 0.093 | 19 | 0 | 0.0 | 4 |
| CST11 | CST11 | Q9H112 | Cystatin-11 | chr20 | GO:0009755 | Not Cancer Driver | No | 38 | 0.275 | 6 | 0 | 0.0 | 0 |
| DAXX_ENST00000266000 | DAXX | Q9UER7 | Death domain-associated protein 6 | chr6 | GO:0009755 | Census, Compendium | Yes | 106 | 0.143 | 549 | 81 | 0.148 | 0 |
| DDX17_ENST00000640332 | DDX17 | Q92841 | Probable ATP-dependent RNA helicase DDX17 | chr22 | GO:0009755 | Not Cancer Driver | No | 91 | 0.125 | 362 | 48 | 0.133 | 0 |
| DDX5 | DDX5 | P17844 | Probable ATP-dependent RNA helicase DDX5 | chr17 | GO:0009755 | Census | Yes | 74 | 0.121 | 225 | 23 | 0.102 | 0 |
| DDX54_ENST00000306014 | DDX54 | Q8TDD1 | ATP-dependent RNA helicase DDX54 | chr12 | GO:0009755 | Not Cancer Driver | No | 113 | 0.128 | 458 | 52 | 0.114 | 0 |
| DEFA3 | DEFA3 | P59666 | Neutrophil defensin 3 | chr8 | GO:0009755 | Not Cancer Driver | No | 15 | 0.16 | 0 | 0 | 0.0 | 0 |
| EGLN2_ENST00000303961 | EGLN2 | Q96KS0 | Prolyl hydroxylase EGLN2 | chr19 | GO:0009755 | Not Cancer Driver | No | 52 | 0.128 | 201 | 17 | 0.085 | 0 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0009755 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
| ESR2 | ESR2 | Q92731 | Estrogen receptor beta | chr14 | GO:0009755 | Not Cancer Driver | No | 90 | 0.17 | 92 | 11 | 0.12 | 1 |
| FKBP4 | FKBP4 | Q02790 | Peptidyl-prolyl cis-trans isomerase FKBP4 | chr12 | GO:0009755 | Not Cancer Driver | No | 46 | 0.1 | 134 | 12 | 0.09 | 0 |
| FSHR | FSHR | P23945 | Follicle-stimulating hormone receptor | chr2 | GO:0009755 | Not Cancer Driver | No | 226 | 0.325 | 28 | 11 | 0.393 | 16 |
| GCGR | GCGR | P47871 | Glucagon receptor | chr17 | GO:0009755 | Not Cancer Driver | No | 16 | 0.034 | 56 | 2 | 0.036 | 4 |
| GHRL_ENST00000457360 | GHRL | Q9UBU3 | Appetite-regulating hormone | chr3 | GO:0009755 | Not Cancer Driver | No | 20 | 0.171 | 52 | 11 | 0.212 | 0 |
| GHR_ENST00000612382 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0009755 | Not Cancer Driver | No | 173 | 0.271 | 229 | 66 | 0.288 | 19 |
| GHSR | GHSR | Q92847 | Growth hormone secretagogue receptor type 1 | chr3 | GO:0009755 | Not Cancer Driver | No | 85 | 0.232 | 4 | 0 | 0.0 | 2 |
| GTF2H1_ENST00000453096 | GTF2H1 | P32780 | General transcription factor IIH subunit 1 | chr11 | GO:0009755 | Not Cancer Driver | No | 52 | 0.095 | 139 | 11 | 0.079 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0009755 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| KDM3A_ENST00000312912 | KDM3A | Q9Y4C1 | Lysine-specific demethylase 3A | chr2 | GO:0009755 | Not Cancer Driver | No | 136 | 0.103 | 461 | 47 | 0.102 | 0 |
| LATS1 | LATS1 | O95835 | Serine/threonine-protein kinase LATS1 | chr6 | GO:0009755 | Census, Compendium | Yes | 161 | 0.142 | 788 | 100 | 0.127 | 0 |
| LATS2 | LATS2 | Q9NRM7 | Serine/threonine-protein kinase LATS2 | chr13 | GO:0009755 | Census, Compendium | Yes | 178 | 0.164 | 687 | 116 | 0.169 | 0 |
| LGR4 | LGR4 | Q9BXB1 | Leucine-rich repeat-containing G-protein coupled receptor 4 | chr11 | GO:0009755 | Not Cancer Driver | No | 108 | 0.114 | 16 | 3 | 0.188 | 0 |
| LGR5 | LGR5 | O75473 | Leucine-rich repeat-containing G-protein coupled receptor 5 | chr12 | GO:0009755 | Not Cancer Driver | No | 124 | 0.137 | 13 | 2 | 0.154 | 0 |
| LHCGR | LHCGR | P22888 | Lutropin-choriogonadotropic hormone receptor | chr2 | GO:0009755 | Not Cancer Driver | No | 181 | 0.259 | 12 | 8 | 0.667 | 25 |
| MED1 | MED1 | Q15648 | Mediator of RNA polymerase II transcription subunit 1 | chr17 | GO:0009755 | Not Cancer Driver | No | 162 | 0.102 | 1104 | 117 | 0.106 | 0 |
| METTL21C | METTL21C | Q5VZV1 | Protein-lysine methyltransferase METTL21C | chr13 | GO:0009755 | Not Cancer Driver | No | 54 | 0.205 | 47 | 13 | 0.277 | 0 |
| NEDD4 | NEDD4 | P46934 | E3 ubiquitin-protein ligase NEDD4 | chr15 | GO:0009755 | Not Cancer Driver | No | 150 | 0.114 | 711 | 79 | 0.111 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0009755 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NR1D1 | NR1D1 | P20393 | Nuclear receptor subfamily 1 group D member 1 | chr17 | GO:0009755 | Not Cancer Driver | No | 81 | 0.132 | 348 | 49 | 0.141 | 0 |
| NR1D2 | NR1D2 | Q14995 | Nuclear receptor subfamily 1 group D member 2 | chr3 | GO:0009755 | Not Cancer Driver | No | 76 | 0.131 | 223 | 25 | 0.112 | 0 |
| NR1H3_ENST00000467728 | NR1H3 | Q13133 | Oxysterols receptor LXR-alpha | chr11 | GO:0009755 | Not Cancer Driver | No | 56 | 0.125 | 146 | 13 | 0.089 | 0 |
| NR3C1_ENST00000343796 | NR3C1 | P04150 | Glucocorticoid receptor | chr5 | GO:0009755 | Not Cancer Driver | No | 92 | 0.118 | 362 | 37 | 0.102 | 12 |
| NR5A1 | NR5A1 | Q13285 | Steroidogenic factor 1 | chr9 | GO:0009755 | Not Cancer Driver | No | 60 | 0.13 | 133 | 29 | 0.218 | 24 |
| NR5A2 | NR5A2 | O00482 | Nuclear receptor subfamily 5 group A member 2 | chr1 | GO:0009755 | Not Cancer Driver | No | 126 | 0.233 | 154 | 35 | 0.227 | 0 |
| OSTN | OSTN | P61366 | Osteocrin | chr3 | GO:0009755 | Not Cancer Driver | No | 30 | 0.226 | 54 | 13 | 0.241 | 0 |
| PADI2 | PADI2 | Q9Y2J8 | Protein-arginine deiminase type-2 | chr1 | GO:0009755 | Not Cancer Driver | No | 121 | 0.182 | 60 | 18 | 0.3 | 0 |
| PGR | PGR | P06401 | Progesterone receptor | chr11 | GO:0009755 | Not Cancer Driver | No | 161 | 0.173 | 480 | 55 | 0.115 | 0 |
| PHB_ENST00000300408 | PHB1 | P35232 | Prohibitin 1 | chr17 | GO:0009755 | Not Cancer Driver | No | 37 | 0.136 | 4 | 1 | 0.25 | 0 |
| PLPP1_ENST00000307259 | PLPP1 | O14494 | Phospholipid phosphatase 1 | chr5 | GO:0009755 | Not Cancer Driver | No | 28 | 0.099 | 27 | 1 | 0.037 | 0 |
| PMEPA1 | PMEPA1 | Q969W9 | Protein TMEPAI | chr20 | GO:0009755 | Not Cancer Driver | No | 45 | 0.157 | 196 | 34 | 0.173 | 0 |
| POU4F2 | POU4F2 | Q12837 | POU domain, class 4, transcription factor 2 | chr4 | GO:0009755 | Not Cancer Driver | No | 130 | 0.318 | 308 | 87 | 0.282 | 0 |
| PPARA_ENST00000402126 | PPARA | Q07869 | Peroxisome proliferator-activated receptor alpha | chr22 | GO:0009755 | Not Cancer Driver | No | 63 | 0.135 | 68 | 9 | 0.132 | 0 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | GO:0009755 | Not Cancer Driver | No | 72 | 0.163 | 69 | 7 | 0.101 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0009755 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PPARGC1B | PPARGC1B | Q86YN6 | Peroxisome proliferator-activated receptor gamma coactivator 1-beta | chr5 | GO:0009755 | Not Cancer Driver | No | 125 | 0.122 | 845 | 99 | 0.117 | 0 |
| PRLR | PRLR | P16471 | Prolactin receptor | chr5 | GO:0009755 | Not Cancer Driver | No | 154 | 0.248 | 282 | 70 | 0.248 | 2 |
| PTGES3_ENST00000262033 | PTGES3 | Q15185 | Prostaglandin E synthase 3 | chr12 | GO:0009755 | Not Cancer Driver | No | 11 | 0.069 | 52 | 3 | 0.058 | 0 |
| PTH | PTH | P01270 | Parathyroid hormone | chr11 | GO:0009755 | Not Cancer Driver | No | 19 | 0.165 | 60 | 10 | 0.167 | 2 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0009755 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| RARA | RARA | P10276 | Retinoic acid receptor alpha | chr17 | GO:0009755 | Census, Compendium | Yes | 70 | 0.152 | 167 | 14 | 0.084 | 0 |
| RARG | RARG | P13631 | Retinoic acid receptor gamma | chr12 | GO:0009755 | Not Cancer Driver | No | 82 | 0.181 | 164 | 24 | 0.146 | 0 |
| RBFOX2_ENST00000449924 | RBFOX2 | O43251 | RNA binding protein fox-1 homolog 2 | chr22 | GO:0009755 | Compendium | Yes | 44 | 0.113 | 173 | 22 | 0.127 | 0 |
| REN | REN | P00797 | Renin | chr1 | GO:0009755 | Not Cancer Driver | No | 60 | 0.148 | 10 | 0 | 0.0 | 3 |
| RHOA | RHOA | P61586 | Transforming protein RhoA | chr3 | GO:0009755 | Census, Compendium | Yes | 99 | 0.513 | 46 | 13 | 0.283 | 2 |
| RHOXF1 | RHOXF1 | Q8NHV9 | Rhox homeobox family member 1 | chrX | GO:0009755 | Not Cancer Driver | No | 41 | 0.223 | 152 | 36 | 0.237 | 0 |
| RNF14 | RNF14 | Q9UBS8 | E3 ubiquitin-protein ligase RNF14 | chr5 | GO:0009755 | Not Cancer Driver | No | 52 | 0.11 | 40 | 8 | 0.2 | 0 |
| RWDD1 | RWDD1 | Q9H446 | RWD domain-containing protein 1 | chr6 | GO:0009755 | Not Cancer Driver | No | 28 | 0.115 | 168 | 19 | 0.113 | 0 |
| RXFP1_ENST00000307765 | RXFP1 | Q9HBX9 | Relaxin receptor 1 | chr4 | GO:0009755 | Not Cancer Driver | No | 152 | 0.201 | 0 | 0 | 0.0 | 0 |
| RXFP2 | RXFP2 | Q8WXD0 | Relaxin receptor 2 | chr13 | GO:0009755 | Not Cancer Driver | No | 137 | 0.182 | 0 | 0 | 0.0 | 1 |
| RXRA | RXRA | P19793 | Retinoic acid receptor RXR-alpha | chr9 | GO:0009755 | Compendium | Yes | 90 | 0.195 | 184 | 26 | 0.141 | 0 |
| SAFB_ENST00000292123 | SAFB | Q15424 | Scaffold attachment factor B1 | chr19 | GO:0009755 | Not Cancer Driver | No | 111 | 0.121 | 911 | 110 | 0.121 | 0 |
| SCGB2A1 | SCGB2A1 | O75556 | Mammaglobin-B | chr11 | GO:0009755 | Not Cancer Driver | No | 14 | 0.147 | 0 | 0 | 0.0 | 0 |
| SCGB2A2 | SCGB2A2 | Q13296 | Mammaglobin-A | chr11 | GO:0009755 | Not Cancer Driver | No | 11 | 0.118 | 0 | 0 | 0.0 | 0 |
| SLC27A1 | SLC27A1 | Q6PCB7 | Long-chain fatty acid transport protein 1 | chr19 | GO:0009755 | Not Cancer Driver | No | 88 | 0.136 | 16 | 0 | 0.0 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0009755 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SST | SST | P61278 | Somatostatin | chr3 | GO:0009755 | Not Cancer Driver | No | 25 | 0.216 | 40 | 15 | 0.375 | 0 |
| SSTR1 | SSTR1 | P30872 | Somatostatin receptor type 1 | chr14 | GO:0009755 | Not Cancer Driver | No | 96 | 0.246 | 50 | 12 | 0.24 | 0 |
| SSTR2 | SSTR2 | P30874 | Somatostatin receptor type 2 | chr17 | GO:0009755 | Not Cancer Driver | No | 54 | 0.146 | 22 | 7 | 0.318 | 0 |
| SSTR3 | SSTR3 | P32745 | Somatostatin receptor type 3 | chr22 | GO:0009755 | Not Cancer Driver | No | 94 | 0.225 | 110 | 26 | 0.236 | 0 |
| SSTR4 | SSTR4 | P31391 | Somatostatin receptor type 4 | chr20 | GO:0009755 | Not Cancer Driver | No | 129 | 0.332 | 39 | 12 | 0.308 | 0 |
| SSTR5 | SSTR5 | P35346 | Somatostatin receptor type 5 | chr16 | GO:0009755 | Not Cancer Driver | No | 60 | 0.165 | 45 | 12 | 0.267 | 0 |
| TADA3 | TADA3 | O75528 | Transcriptional adapter 3 | chr3 | GO:0009755 | Not Cancer Driver | No | 54 | 0.125 | 353 | 43 | 0.122 | 0 |
| TAF7 | TAF7 | Q15545 | Transcription initiation factor TFIID subunit 7 | chr5 | GO:0009755 | Not Cancer Driver | No | 40 | 0.115 | 258 | 31 | 0.12 | 0 |
| THRA | THRA | P10827 | Thyroid hormone receptor alpha | chr17 | GO:0009755 | Not Cancer Driver | No | 69 | 0.141 | 207 | 30 | 0.145 | 2 |
| THRB_ENST00000415021 | THRB | P10828 | Thyroid hormone receptor beta | chr3 | GO:0009755 | Not Cancer Driver | No | 87 | 0.189 | 113 | 28 | 0.248 | 33 |
| TMF1 | TMF1 | P82094 | TATA element modulatory factor | chr3 | GO:0009755 | Not Cancer Driver | No | 109 | 0.1 | 946 | 99 | 0.105 | 0 |
| TRERF1_ENST00000372922 | TRERF1 | Q96PN7 | Transcriptional-regulating factor 1 | chr6 | GO:0009755 | Not Cancer Driver | No | 226 | 0.188 | 957 | 167 | 0.175 | 0 |
| TRH | TRH | P20396 | Pro-thyrotropin-releasing hormone | chr3 | GO:0009755 | Not Cancer Driver | No | 45 | 0.186 | 217 | 41 | 0.189 | 0 |
| TRIP4 | TRIP4 | Q15650 | Activating signal cointegrator 1 | chr15 | GO:0009755 | Not Cancer Driver | No | 71 | 0.122 | 176 | 27 | 0.153 | 0 |
| TSHR | TSHR | P16473 | Thyrotropin receptor | chr14 | GO:0009755 | Census | Yes | 128 | 0.168 | 38 | 9 | 0.237 | 39 |
| UBE3A | UBE3A | Q05086 | Ubiquitin-protein ligase E3A | chr15 | GO:0009755 | Not Cancer Driver | No | 141 | 0.161 | 136 | 22 | 0.162 | 0 |
| UBR5 | UBR5 | O95071 | E3 ubiquitin-protein ligase UBR5 | chr8 | GO:0009755 | Census, Compendium | Yes | 340 | 0.121 | 1296 | 162 | 0.125 | 0 |
| UCN2 | UCN2 | Q96RP3 | Urocortin-2 | chr3 | GO:0009755 | Not Cancer Driver | No | 10 | 0.089 | 48 | 4 | 0.083 | 0 |
| UCN3 | UCN3 | Q969E3 | Urocortin-3 | chr10 | GO:0009755 | Not Cancer Driver | No | 22 | 0.137 | 74 | 11 | 0.149 | 0 |
| WBP2_ENST00000254806 | WBP2 | Q969T9 | WW domain-binding protein 2 | chr17 | GO:0009755 | Not Cancer Driver | No | 26 | 0.1 | 102 | 6 | 0.059 | 1 |
| YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0009755 | Not Cancer Driver | No | 51 | 0.101 | 489 | 49 | 0.1 | 0 |
| YWHAH | YWHAH | Q04917 | 14-3-3 protein eta | chr22 | GO:0009755 | Not Cancer Driver | No | 15 | 0.061 | 55 | 3 | 0.055 | 0 |
| ZMIZ1 | ZMIZ1 | Q9ULJ6 | Zinc finger MIZ domain-containing protein 1 | chr10 | GO:0009755 | Not Cancer Driver | No | 148 | 0.139 | 762 | 111 | 0.146 | 5 |