Total number of protein in "GO:0009636" GO term: 94
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABTB2 | ABTB2 | Q8N961 | Ankyrin repeat and BTB/POZ domain-containing protein 2 | chr11 | GO:0009636 | Not Cancer Driver | No | 95 | 0.093 | 215 | 20 | 0.093 | 0 |
| ADAMTS13 | ADAMTS13 | Q76LX8 | A disintegrin and metalloproteinase with thrombospondin motifs 13 | chr9 | GO:0009636 | Not Cancer Driver | No | 172 | 0.121 | 285 | 35 | 0.123 | 43 |
| AHR | AHR | P35869 | Aryl hydrocarbon receptor | chr7 | GO:0009636 | Not Cancer Driver | No | 129 | 0.152 | 351 | 75 | 0.214 | 0 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0009636 | Not Cancer Driver | No | 88 | 0.144 | 166 | 22 | 0.133 | 11 |
| ALAD | ALAD | P13716 | Delta-aminolevulinic acid dehydratase | chr9 | GO:0009636 | Not Cancer Driver | No | 52 | 0.158 | 13 | 3 | 0.231 | 5 |
| AQP10 | AQP10 | Q96PS8 | Aquaporin-10 | chr1 | GO:0009636 | Not Cancer Driver | No | 73 | 0.243 | 15 | 1 | 0.067 | 0 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0009636 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0009636 | Not Cancer Driver | No | 65 | 0.158 | 63 | 8 | 0.127 | 86 |
| ATF4_ENST00000404241 | ATF4 | P18848 | Cyclic AMP-dependent transcription factor ATF-4 | chr22 | GO:0009636 | Not Cancer Driver | No | 53 | 0.151 | 259 | 38 | 0.147 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0009636 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0009636 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0009636 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BLMH | BLMH | Q13867 | Bleomycin hydrolase | chr17 | GO:0009636 | Not Cancer Driver | No | 54 | 0.119 | 15 | 1 | 0.067 | 0 |
| BPHL | BPHL | Q86WA6 | Valacyclovir hydrolase | chr6 | GO:0009636 | Not Cancer Driver | No | 35 | 0.12 | 12 | 1 | 0.083 | 0 |
| BRIP1 | BRIP1 | Q9BX63 | Fanconi anemia group J protein | chr17 | GO:0009636 | Census | Yes | 174 | 0.139 | 397 | 59 | 0.149 | 6 |
| CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | GO:0009636 | Census, Compendium | Yes | 150 | 0.17 | 400 | 82 | 0.205 | 5 |
| CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0009636 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
| CERS1_ENST00000623882 | CERS1 | P27544 | Ceramide synthase 1 | chr19 | GO:0009636 | Not Cancer Driver | No | 29 | 0.083 | 19 | 0 | 0.0 | 1 |
| CES1_ENST00000361503 | CES1 | P23141 | Liver carboxylesterase 1 | chr16 | GO:0009636 | Not Cancer Driver | No | 138 | 0.243 | 41 | 2 | 0.049 | 0 |
| CLDN1 | CLDN1 | O95832 | Claudin-1 | chr3 | GO:0009636 | Not Cancer Driver | No | 31 | 0.147 | 16 | 3 | 0.188 | 0 |
| CNP | CNP | P09543 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | chr17 | GO:0009636 | Not Cancer Driver | No | 36 | 0.086 | 71 | 2 | 0.028 | 0 |
| CPOX | CPOX | P36551 | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial | chr3 | GO:0009636 | Not Cancer Driver | No | 49 | 0.108 | 126 | 7 | 0.056 | 17 |
| CPS1_ENST00000233072 | CPS1 | P31327 | Carbamoyl-phosphate synthase [ammonia], mitochondrial | chr2 | GO:0009636 | Not Cancer Driver | No | 368 | 0.245 | 73 | 22 | 0.301 | 140 |
| CYP1A1 | CYP1A1 | P04798 | Cytochrome P450 1A1 | chr15 | GO:0009636 | Not Cancer Driver | No | 81 | 0.158 | 17 | 2 | 0.118 | 0 |
| CYP1B1 | CYP1B1 | Q16678 | Cytochrome P450 1B1 | chr2 | GO:0009636 | Not Cancer Driver | No | 61 | 0.112 | 31 | 3 | 0.097 | 40 |
| CYP2F1 | CYP2F1 | P24903 | Cytochrome P450 2F1 | chr19 | GO:0009636 | Not Cancer Driver | No | 85 | 0.173 | 2 | 0 | 0.0 | 0 |
| DDC | DDC | P20711 | Aromatic-L-amino-acid decarboxylase | chr7 | GO:0009636 | Not Cancer Driver | No | 98 | 0.204 | 5 | 0 | 0.0 | 9 |
| DHRS2_ENST00000250383 | DHRS2 | Q13268 | Dehydrogenase/reductase SDR family member 2, mitochondrial | chr14 | GO:0009636 | Not Cancer Driver | No | 47 | 0.168 | 0 | 0 | 0.0 | 0 |
| DHX15 | DHX15 | O43143 | ATP-dependent RNA helicase DHX15 | chr4 | GO:0009636 | Not Cancer Driver | No | 110 | 0.138 | 180 | 30 | 0.167 | 0 |
| DNMT3A | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | GO:0009636 | Census, Compendium | Yes | 194 | 0.213 | 371 | 59 | 0.159 | 16 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0009636 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| EHMT2_ENST00000375537 | EHMT2 | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | chr6 | GO:0009636 | Not Cancer Driver | No | 142 | 0.117 | 585 | 71 | 0.121 | 0 |
| EPHX1_ENST00000366837 | EPHX1 | P07099 | Epoxide hydrolase 1 | chr1 | GO:0009636 | Not Cancer Driver | No | 75 | 0.165 | 7 | 3 | 0.429 | 0 |
| EPHX2 | EPHX2 | P34913 | Bifunctional epoxide hydrolase 2 | chr8 | GO:0009636 | Not Cancer Driver | No | 78 | 0.141 | 26 | 3 | 0.115 | 0 |
| ERCC6 | ERCC6 | Q03468 | DNA excision repair protein ERCC-6 | chr10 | GO:0009636 | Not Cancer Driver | No | 211 | 0.141 | 829 | 117 | 0.141 | 9 |
| FOS | FOS | P01100 | Protein c-Fos | chr14 | GO:0009636 | Not Cancer Driver | No | 45 | 0.118 | 245 | 33 | 0.135 | 0 |
| GABRB1 | GABRB1 | P18505 | Gamma-aminobutyric acid receptor subunit beta-1 | chr4 | GO:0009636 | Not Cancer Driver | No | 133 | 0.281 | 43 | 14 | 0.326 | 2 |
| GATA6 | GATA6 | Q92908 | Transcription factor GATA-6 | chr18 | GO:0009636 | Not Cancer Driver | No | 57 | 0.096 | 476 | 51 | 0.107 | 10 |
| GFER | GFER | P55789 | FAD-linked sulfhydryl oxidase ALR | chr16 | GO:0009636 | Not Cancer Driver | No | 10 | 0.049 | 97 | 4 | 0.041 | 1 |
| GJC2 | GJC2 | Q5T442 | Gap junction gamma-2 protein | chr1 | GO:0009636 | Not Cancer Driver | No | 33 | 0.075 | 225 | 10 | 0.044 | 6 |
| GLYAT | GLYAT | Q6IB77 | Glycine N-acyltransferase | chr11 | GO:0009636 | Not Cancer Driver | No | 75 | 0.253 | 9 | 2 | 0.222 | 0 |
| GUCY2C | GUCY2C | P25092 | Guanylyl cyclase C | chr12 | GO:0009636 | Not Cancer Driver | No | 209 | 0.195 | 51 | 7 | 0.137 | 2 |
| HTRA2 | HTRA2 | O43464 | Serine protease HTRA2, mitochondrial | chr2 | GO:0009636 | Compendium | Yes | 44 | 0.096 | 127 | 9 | 0.071 | 2 |
| INHBB | INHBB | P09529 | Inhibin beta B chain | chr2 | GO:0009636 | Not Cancer Driver | No | 61 | 0.15 | 98 | 5 | 0.051 | 0 |
| INMT | INMT | O95050 | Indolethylamine N-methyltransferase | chr7 | GO:0009636 | Not Cancer Driver | No | 64 | 0.243 | 5 | 0 | 0.0 | 0 |
| KCNC1_ENST00000379472 | KCNC1 | P48547 | Potassium voltage-gated channel subfamily C member 1 | chr11 | GO:0009636 | Not Cancer Driver | No | 91 | 0.178 | 110 | 18 | 0.164 | 1 |
| KCNC2 | KCNC2 | Q96PR1 | Potassium voltage-gated channel subfamily C member 2 | chr12 | GO:0009636 | Not Cancer Driver | No | 161 | 0.252 | 255 | 63 | 0.247 | 0 |
| KDM1A_ENST00000356634 | KDM1A | O60341 | Lysine-specific histone demethylase 1A | chr1 | GO:0009636 | Not Cancer Driver | No | 67 | 0.079 | 291 | 28 | 0.096 | 3 |
| KDM5B_ENST00000367265 | KDM5B | Q9UGL1 | Lysine-specific demethylase 5B | chr1 | GO:0009636 | Not Cancer Driver | No | 219 | 0.142 | 388 | 58 | 0.149 | 0 |
| KDM5C | KDM5C | P41229 | Lysine-specific demethylase 5C | chrX | GO:0009636 | Census, Compendium | Yes | 167 | 0.107 | 499 | 46 | 0.092 | 10 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0009636 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MAOB | MAOB | P27338 | Amine oxidase [flavin-containing] B | chrX | GO:0009636 | Not Cancer Driver | No | 75 | 0.144 | 44 | 6 | 0.136 | 0 |
| MAP1B | MAP1B | P46821 | Microtubule-associated protein 1B | chr5 | GO:0009636 | Not Cancer Driver | No | 332 | 0.135 | 1947 | 278 | 0.143 | 0 |
| MBP_ENST00000580402 | MBP | P02686 | Myelin basic protein | chr18 | GO:0009636 | Not Cancer Driver | No | 52 | 0.171 | 304 | 52 | 0.171 | 0 |
| MPST_ENST00000341116 | MPST | P25325 | 3-mercaptopyruvate sulfurtransferase | chr22 | GO:0009636 | Not Cancer Driver | No | 20 | 0.067 | 72 | 8 | 0.111 | 0 |
| NEFL | NEFL | P07196 | Neurofilament light polypeptide | chr8 | GO:0009636 | Not Cancer Driver | No | 92 | 0.169 | 285 | 39 | 0.137 | 12 |
| NQO1 | NQO1 | P15559 | NAD(P)H dehydrogenase [quinone] 1 | chr16 | GO:0009636 | Not Cancer Driver | No | 21 | 0.077 | 10 | 1 | 0.1 | 0 |
| NUPR1_ENST00000324873 | NUPR1 | O60356 | Nuclear protein 1 | chr16 | GO:0009636 | Not Cancer Driver | No | 10 | 0.122 | 82 | 10 | 0.122 | 0 |
| OPRD1 | OPRD1 | P41143 | Delta-type opioid receptor | chr1 | GO:0009636 | Not Cancer Driver | No | 91 | 0.245 | 30 | 3 | 0.1 | 0 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0009636 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PDZD3_ENST00000531114 | PDZD3 | Q86UT5 | Na(+)/H(+) exchange regulatory cofactor NHE-RF4 | chr11 | GO:0009636 | Not Cancer Driver | No | 58 | 0.102 | 199 | 19 | 0.095 | 0 |
| PENK_ENST00000451791 | PENK | P01210 | Proenkephalin-A | chr8 | GO:0009636 | Not Cancer Driver | No | 109 | 0.408 | 142 | 62 | 0.437 | 0 |
| PINK1 | PINK1 | Q9BXM7 | Serine/threonine-protein kinase PINK1, mitochondrial | chr1 | GO:0009636 | Not Cancer Driver | No | 57 | 0.098 | 99 | 13 | 0.131 | 23 |
| PON1 | PON1 | P27169 | Serum paraoxonase/arylesterase 1 | chr7 | GO:0009636 | Not Cancer Driver | No | 80 | 0.225 | 10 | 9 | 0.9 | 0 |
| PON2 | PON2 | Q15165 | Serum paraoxonase/arylesterase 2 | chr7 | GO:0009636 | Not Cancer Driver | No | 46 | 0.13 | 13 | 3 | 0.231 | 0 |
| PON3 | PON3 | Q15166 | Serum paraoxonase/lactonase 3 | chr7 | GO:0009636 | Not Cancer Driver | No | 69 | 0.195 | 32 | 6 | 0.188 | 0 |
| PRKCG | PRKCG | P05129 | Protein kinase C gamma type | chr19 | GO:0009636 | Not Cancer Driver | No | 172 | 0.247 | 151 | 43 | 0.285 | 5 |
| PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0009636 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
| RAD51_ENST00000267868 | RAD51 | Q06609 | DNA repair protein RAD51 homolog 1 | chr15 | GO:0009636 | Not Cancer Driver | No | 42 | 0.124 | 47 | 5 | 0.106 | 3 |
| RPS6KB1 | RPS6KB1 | P23443 | Ribosomal protein S6 kinase beta-1 | chr17 | GO:0009636 | Not Cancer Driver | No | 45 | 0.086 | 226 | 26 | 0.115 | 0 |
| SCFD1 | SCFD1 | Q8WVM8 | Sec1 family domain-containing protein 1 | chr14 | GO:0009636 | Not Cancer Driver | No | 66 | 0.103 | 117 | 12 | 0.103 | 0 |
| SCN2B | SCN2B | O60939 | Sodium channel subunit beta-2 | chr11 | GO:0009636 | Not Cancer Driver | No | 46 | 0.214 | 52 | 7 | 0.135 | 2 |
| SCN9A_ENST00000642356 | SCN9A | Q15858 | Sodium channel protein type 9 subunit alpha | chr2 | GO:0009636 | Not Cancer Driver | No | 461 | 0.232 | 490 | 126 | 0.257 | 21 |
| SDC1_ENST00000254351 | SDC1 | P18827 | Syndecan-1 | chr2 | GO:0009636 | Not Cancer Driver | No | 31 | 0.1 | 259 | 30 | 0.116 | 0 |
| SLC18A2_ENST00000644641 | SLC18A2 | Q05940 | Synaptic vesicular amine transporter | chr10 | GO:0009636 | Not Cancer Driver | No | 105 | 0.204 | 23 | 7 | 0.304 | 1 |
| SLC22A8 | SLC22A8 | Q8TCC7 | Solute carrier family 22 member 8 | chr11 | GO:0009636 | Not Cancer Driver | No | 104 | 0.192 | 64 | 17 | 0.266 | 0 |
| SLC23A1_ENST00000348729 | SLC23A1 | Q9UHI7 | Solute carrier family 23 member 1 | chr5 | GO:0009636 | Not Cancer Driver | No | 74 | 0.124 | 47 | 5 | 0.106 | 0 |
| SLC30A4 | SLC30A4 | O14863 | Zinc transporter 4 | chr15 | GO:0009636 | Not Cancer Driver | No | 44 | 0.103 | 54 | 8 | 0.148 | 0 |
| SLC6A14 | SLC6A14 | Q9UN76 | Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) | chrX | GO:0009636 | Not Cancer Driver | No | 116 | 0.181 | 27 | 3 | 0.111 | 0 |
| SLC6A1_ENST00000643498 | SLC6A1 | P30531 | Sodium- and chloride-dependent GABA transporter 1 | chr3 | GO:0009636 | Not Cancer Driver | No | 119 | 0.199 | 24 | 9 | 0.375 | 4 |
| SLC6A4_ENST00000401766 | SLC6A4 | P31645 | Sodium-dependent serotonin transporter | chr17 | GO:0009636 | Not Cancer Driver | No | 101 | 0.16 | 73 | 12 | 0.164 | 0 |
| SLC7A11 | SLC7A11 | Q9UPY5 | Cystine/glutamate transporter | chr4 | GO:0009636 | Not Cancer Driver | No | 70 | 0.14 | 15 | 2 | 0.133 | 0 |
| SLC7A8 | SLC7A8 | Q9UHI5 | Large neutral amino acids transporter small subunit 2 | chr14 | GO:0009636 | Not Cancer Driver | No | 70 | 0.131 | 63 | 11 | 0.175 | 0 |
| SNN | SNN | O75324 | Stannin | chr16 | GO:0009636 | Not Cancer Driver | No | 10 | 0.114 | 23 | 1 | 0.043 | 0 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0009636 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| SRF | SRF | P11831 | Serum response factor | chr6 | GO:0009636 | Not Cancer Driver | No | 44 | 0.087 | 443 | 42 | 0.095 | 0 |
| SRSF9 | SRSF9 | Q13242 | Serine/arginine-rich splicing factor 9 | chr12 | GO:0009636 | Not Cancer Driver | No | 20 | 0.09 | 111 | 8 | 0.072 | 0 |
| TH | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0009636 | Not Cancer Driver | No | 61 | 0.116 | 149 | 21 | 0.141 | 38 |
| TLR2 | TLR2 | O60603 | Toll-like receptor 2 | chr4 | GO:0009636 | Not Cancer Driver | No | 108 | 0.138 | 0 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0009636 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TRPM6 | TRPM6 | Q9BX84 | Transient receptor potential cation channel subfamily M member 6 | chr9 | GO:0009636 | Not Cancer Driver | No | 431 | 0.213 | 458 | 99 | 0.216 | 6 |
| TTPA | TTPA | P49638 | Alpha-tocopherol transfer protein | chr8 | GO:0009636 | Not Cancer Driver | No | 53 | 0.191 | 20 | 1 | 0.05 | 7 |
| TYMS | TYMS | P04818 | Thymidylate synthase | chr18 | GO:0009636 | Not Cancer Driver | No | 22 | 0.07 | 41 | 0 | 0.0 | 0 |
| WAPL_ENST00000618527 | WAPL | Q7Z5K2 | Wings apart-like protein homolog | chr10 | GO:0009636 | Not Cancer Driver | No | 140 | 0.118 | 621 | 68 | 0.11 | 0 |