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Total number of protein in "GO:0009314" GO term:  354

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AANAT_ENST00000392492 AANAT Q16613 Serotonin N-acetyltransferase chr17 GO:0009314 Not Cancer Driver No 22 0.106 28 4 0.143 0
ABCA4 ABCA4 P78363 Retinal-specific phospholipid-transporting ATPase ABCA4 chr1 GO:0009314 Not Cancer Driver No 363 0.16 244 33 0.135 226
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0009314 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0009314 Not Cancer Driver No 255 0.161 138 23 0.167 97
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 GO:0009314 Not Cancer Driver No 63 0.104 163 23 0.141 0
ADAM2 ADAM2 Q99965 Disintegrin and metalloproteinase domain-containing protein 2 chr8 GO:0009314 Not Cancer Driver No 194 0.264 18 4 0.222 0
AGRP AGRP O00253 Agouti-related protein chr16 GO:0009314 Not Cancer Driver No 13 0.098 32 4 0.125 0
AIPL1 AIPL1 Q9NZN9 Aryl-hydrocarbon-interacting protein-like 1 chr17 GO:0009314 Not Cancer Driver No 52 0.135 113 14 0.124 2
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0009314 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0009314 Census Yes 77 0.16 84 9 0.107 2
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0009314 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0009314 Not Cancer Driver No 59 0.171 61 12 0.197 0
APOBEC1 APOBEC1 P41238 C->U-editing enzyme APOBEC-1 chr12 GO:0009314 Not Cancer Driver No 62 0.263 13 1 0.077 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0009314 Not Cancer Driver No 128 0.166 418 71 0.17 17
AQP1 AQP1 P29972 Aquaporin-1 chr7 GO:0009314 Not Cancer Driver No 39 0.145 4 1 0.25 0
AQP4 AQP4 P55087 Aquaporin-4 chr18 GO:0009314 Not Cancer Driver No 50 0.155 30 9 0.3 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0009314 Not Cancer Driver No 101 0.197 49 1 0.02 0
ATF4_ENST00000404241 ATF4 P18848 Cyclic AMP-dependent transcription factor ATF-4 chr22 GO:0009314 Not Cancer Driver No 53 0.151 259 38 0.147 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0009314 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATOH7 ATOH7 Q8N100 Transcription factor ATOH7 chr10 GO:0009314 Not Cancer Driver No 10 0.066 40 3 0.075 2
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0009314 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP8A2 ATP8A2 Q9NTI2 Phospholipid-transporting ATPase IB chr13 GO:0009314 Not Cancer Driver No 236 0.199 78 14 0.179 1
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0009314 Census, Compendium Yes 338 0.128 106 14 0.132 1
AURKB_ENST00000585124 AURKB Q96GD4 Aurora kinase B chr17 GO:0009314 Not Cancer Driver No 51 0.148 63 8 0.127 0
B4GALT2_ENST00000372324 B4GALT2 O60909 Beta-1,4-galactosyltransferase 2 chr1 GO:0009314 Not Cancer Driver No 53 0.142 105 14 0.133 0
BABAM2_ENST00000342045 BABAM2 Q9NXR7 BRISC and BRCA1-A complex member 2 chr2 GO:0009314 Not Cancer Driver No 52 0.136 0 0 0.0 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0009314 Not Cancer Driver No 55 0.11 53 5 0.094 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0009314 Not Cancer Driver No 38 0.18 58 9 0.155 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0009314 Census Yes 96 0.124 384 49 0.128 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0009314 Census Yes 30 0.156 39 2 0.051 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0009314 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0009314 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0009314 Census Yes 44 0.097 259 23 0.089 0
BEST1_ENST00000378043 BEST1 O76090 Bestrophin-1 chr11 GO:0009314 Not Cancer Driver No 47 0.08 229 18 0.079 108
BHLHE40 BHLHE40 O14503 Class E basic helix-loop-helix protein 40 chr3 GO:0009314 Not Cancer Driver No 52 0.126 242 31 0.128 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0009314 Census Yes 153 0.108 667 70 0.105 8
BMF_ENST00000561360 BMF Q96LC9 Bcl-2-modifying factor chr15 GO:0009314 Not Cancer Driver No 22 0.12 94 9 0.096 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0009314 Census, Compendium Yes 224 0.12 1458 174 0.119 35
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0009314 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0009314 Not Cancer Driver No 39 0.123 74 7 0.095 0
CABP4 CABP4 P57796 Calcium-binding protein 4 chr11 GO:0009314 Not Cancer Driver No 61 0.222 188 47 0.25 1
CACNA1F CACNA1F O60840 Voltage-dependent L-type calcium channel subunit alpha-1F chrX GO:0009314 Not Cancer Driver No 284 0.144 530 78 0.147 20
CACNA2D4 CACNA2D4 Q7Z3S7 Voltage-dependent calcium channel subunit alpha-2/delta-4 chr12 GO:0009314 Not Cancer Driver No 211 0.186 70 9 0.129 0
CARD16 CARD16 Q5EG05 Caspase recruitment domain-containing protein 16 chr11 GO:0009314 Not Cancer Driver No 36 0.183 23 7 0.304 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0009314 Census Yes 32 0.116 62 5 0.081 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0009314 Census Yes 49 0.118 71 7 0.099 0
CAT CAT P04040 Catalase chr11 GO:0009314 Not Cancer Driver No 70 0.133 176 18 0.102 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0009314 Census, Compendium Yes 115 0.127 512 56 0.109 4
CCDC66 CCDC66 A2RUB6 Coiled-coil domain-containing protein 66 chr3 GO:0009314 Not Cancer Driver No 91 0.096 811 77 0.095 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0009314 Not Cancer Driver No 18 0.186 14 3 0.214 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0009314 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCR4 CCR4 P51679 C-C chemokine receptor type 4 chr3 GO:0009314 Census Yes 45 0.125 0 0 0.0 0
CDC25A CDC25A P30304 M-phase inducer phosphatase 1 chr3 GO:0009314 Not Cancer Driver No 63 0.12 313 35 0.112 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0009314 Not Cancer Driver No 48 0.164 5 1 0.2 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0009314 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDS1 CDS1 Q92903 Phosphatidate cytidylyltransferase 1 chr4 GO:0009314 Not Cancer Driver No 73 0.158 66 9 0.136 0
CEP250 CEP250 Q9BV73 Centrosome-associated protein CEP250 chr20 GO:0009314 Not Cancer Driver No 250 0.102 1859 195 0.105 0
CERS1_ENST00000623882 CERS1 P27544 Ceramide synthase 1 chr19 GO:0009314 Not Cancer Driver No 29 0.083 19 0 0.0 1
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0009314 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0009314 Census, Compendium Yes 335 0.617 157 130 0.828 13
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0009314 Not Cancer Driver No 92 0.183 23 2 0.087 2
CLOCK CLOCK O15516 Circadian locomoter output cycles protein kaput chr4 GO:0009314 Not Cancer Driver No 83 0.098 458 38 0.083 0
CNGB1 CNGB1 Q14028 Cyclic nucleotide-gated cation channel beta-1 chr16 GO:0009314 Not Cancer Driver No 206 0.165 789 120 0.152 1
COL3A1 COL3A1 P02461 Collagen alpha-1(III) chain chr2 GO:0009314 Census Yes 402 0.274 1182 337 0.285 103
COPS9_ENST00000607357 COPS9 Q8WXC6 COP9 signalosome complex subunit 9 chr2 GO:0009314 Not Cancer Driver No 6 0.105 25 3 0.12 0
CPT1B_ENST00000405237 CPT1B Q92523 Carnitine O-palmitoyltransferase 1, muscle isoform chr22 GO:0009314 Not Cancer Driver No 89 0.115 50 8 0.16 0
CRB1 CRB1 P82279 Protein crumbs homolog 1 chr1 GO:0009314 Not Cancer Driver No 464 0.33 28 5 0.179 74
CREBBP CREBBP Q92793 CREB-binding protein chr16 GO:0009314 Census, Compendium Yes 412 0.169 1796 247 0.138 33
CRIP1_ENST00000409393 CRIP1 P50238 Cysteine-rich protein 1 chr14 GO:0009314 Not Cancer Driver No 6 0.078 8 1 0.125 0
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:0009314 Census, Compendium Yes 63 0.099 606 62 0.102 0
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0009314 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0009314 Not Cancer Driver No 72 0.121 100 12 0.12 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0009314 Not Cancer Driver No 22 0.126 59 11 0.186 4
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:0009314 Not Cancer Driver No 34 0.093 0 0 0.0 31
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0009314 Not Cancer Driver No 138 0.151 207 38 0.184 2
CXCL10 CXCL10 P02778 C-X-C motif chemokine 10 chr4 GO:0009314 Not Cancer Driver No 19 0.194 12 4 0.333 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0009314 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYBA CYBA P13498 Cytochrome b-245 light chain chr16 GO:0009314 Not Cancer Driver No 26 0.133 66 2 0.03 12
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0009314 Not Cancer Driver No 125 0.203 71 17 0.239 3
DCT_ENST00000377028 DCT P40126 L-dopachrome tautomerase chr13 GO:0009314 Not Cancer Driver No 113 0.218 19 4 0.211 2
DCUN1D3 DCUN1D3 Q8IWE4 DCN1-like protein 3 chr16 GO:0009314 Not Cancer Driver No 36 0.118 118 9 0.076 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0009314 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0009314 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDHD2_ENST00000520272 DDHD2 O94830 Phospholipase DDHD2 chr8 GO:0009314 Not Cancer Driver No 95 0.134 169 25 0.148 1
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0009314 Not Cancer Driver No 159 0.158 222 39 0.176 0
DNM2_ENST00000355667 DNM2 P50570 Dynamin-2 chr19 GO:0009314 Census Yes 138 0.159 270 43 0.159 22
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0009314 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0009314 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0009314 Not Cancer Driver No 88 0.22 45 17 0.378 0
DYNLRB1 DYNLRB1 Q9NP97 Dynein light chain roadblock-type 1 chr20 GO:0009314 Not Cancer Driver No 23 0.24 19 4 0.211 0
ECT2 ECT2 Q9H8V3 Protein ECT2 chr3 GO:0009314 Not Cancer Driver No 104 0.114 284 33 0.116 0
EEF1D_ENST00000395119 EEF1D P29692 Elongation factor 1-delta chr8 GO:0009314 Not Cancer Driver No 40 0.142 153 22 0.144 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0009314 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0009314 Not Cancer Driver No 78 0.144 501 72 0.144 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0009314 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF2S1 EIF2S1 P05198 Eukaryotic translation initiation factor 2 subunit 1 chr14 GO:0009314 Not Cancer Driver No 35 0.111 59 6 0.102 0
ELK1_ENST00000376983 ELK1 P19419 ETS domain-containing protein Elk-1 chrX GO:0009314 Not Cancer Driver No 51 0.119 327 34 0.104 0
ELOVL4 ELOVL4 Q9GZR5 Elongation of very long chain fatty acids protein 4 chr6 GO:0009314 Not Cancer Driver No 68 0.217 23 6 0.261 1
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0009314 Census, Compendium Yes 334 0.138 1790 196 0.109 1
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0009314 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0009314 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0009314 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0009314 Census Yes 120 0.131 225 27 0.12 15
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0009314 Census Yes 175 0.148 816 121 0.148 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0009314 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0009314 Not Cancer Driver No 25 0.063 53 8 0.151 7
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0009314 Census Yes 107 0.143 58 7 0.121 12
EYS EYS Q5T1H1 Protein eyes shut homolog chr6 GO:0009314 Not Cancer Driver No 447 0.141 109 9 0.083 16
FAM19A2_ENST00000551619 TAFA2 Q8N3H0 Chemokine-like protein TAFA-2 chr12 GO:0009314 Not Cancer Driver No 55 0.42 4 1 0.25 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0009314 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCG FANCG O15287 Fanconi anemia group G protein chr9 GO:0009314 Census Yes 64 0.103 48 3 0.062 1
FBXL12 FBXL12 Q9NXK8 F-box/LRR-repeat protein 12 chr19 GO:0009314 Not Cancer Driver No 41 0.126 0 0 0.0 0
FBXL17 FBXL17 Q9UF56 F-box/LRR-repeat protein 17 chr5 GO:0009314 Not Cancer Driver No 58 0.083 194 1 0.005 0
FBXL22 FBXL22 Q6P050 F-box and leucine-rich protein 22 chr15 GO:0009314 Not Cancer Driver No 15 0.061 125 3 0.024 0
FBXL3 FBXL3 Q9UKT7 F-box/LRR-repeat protein 3 chr13 GO:0009314 Not Cancer Driver No 49 0.114 30 6 0.2 1
FBXL6 FBXL6 Q8N531 F-box/LRR-repeat protein 6 chr8 GO:0009314 Not Cancer Driver No 48 0.089 114 5 0.044 0
FBXL8 FBXL8 Q96CD0 F-box/LRR-repeat protein 8 chr16 GO:0009314 Not Cancer Driver No 19 0.051 7 0 0.0 0
FBXO4 FBXO4 Q9UKT5 F-box only protein 4 chr5 GO:0009314 Not Cancer Driver No 55 0.142 68 7 0.103 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0009314 Census Yes 35 0.092 111 11 0.099 0
FIGNL1 FIGNL1 Q6PIW4 Fidgetin-like protein 1 chr7 GO:0009314 Not Cancer Driver No 75 0.111 224 23 0.103 0
FKBPL FKBPL Q9UIM3 FK506-binding protein-like chr6 GO:0009314 Not Cancer Driver No 48 0.138 202 28 0.139 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0009314 Not Cancer Driver No 124 0.196 327 70 0.214 3
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0009314 Not Cancer Driver No 31 0.095 114 5 0.044 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0009314 Not Cancer Driver No 38 0.088 186 16 0.086 10
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0009314 Not Cancer Driver No 10 0.061 39 5 0.128 0
GATA3_ENST00000346208 GATA3 P23771 Trans-acting T-cell-specific transcription factor GATA-3 chr10 GO:0009314 Census, Compendium Yes 111 0.251 364 87 0.239 2
GJA10 GJA10 Q969M2 Gap junction alpha-10 protein chr6 GO:0009314 Not Cancer Driver No 135 0.249 210 42 0.2 0
GNA11 GNA11 P29992 Guanine nucleotide-binding protein subunit alpha-11 chr19 GO:0009314 Census, Compendium Yes 48 0.134 10 0 0.0 5
GNAQ GNAQ P50148 Guanine nucleotide-binding protein G(q) subunit alpha chr9 GO:0009314 Census, Compendium Yes 57 0.159 14 1 0.071 1
GNAT1 GNAT1 P11488 Guanine nucleotide-binding protein G(t) subunit alpha-1 chr3 GO:0009314 Not Cancer Driver No 43 0.123 39 6 0.154 3
GNAT2 GNAT2 P19087 Guanine nucleotide-binding protein G(t) subunit alpha-2 chr1 GO:0009314 Not Cancer Driver No 38 0.107 44 7 0.159 0
GNB5 GNB5 O14775 Guanine nucleotide-binding protein subunit beta-5 chr15 GO:0009314 Not Cancer Driver No 60 0.152 16 1 0.062 1
GNGT1_ENST00000429473 GNGT1 P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 chr7 GO:0009314 Not Cancer Driver No 14 0.189 25 4 0.16 0
GNGT2_ENST00000511673 GNGT2 O14610 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 chr17 GO:0009314 Not Cancer Driver No 15 0.217 65 14 0.215 0
GPR52 GPR52 Q9Y2T5 G-protein coupled receptor 52 chr1 GO:0009314 Not Cancer Driver No 48 0.133 9 2 0.222 0
GPR88 GPR88 Q9GZN0 Probable G-protein coupled receptor 88 chr1 GO:0009314 Not Cancer Driver No 15 0.039 30 0 0.0 0
GPX1_ENST00000620890 GPX1 P07203 Glutathione peroxidase 1 chr3 GO:0009314 Not Cancer Driver No 38 0.187 12 1 0.083 0
GRB2_ENST00000392564 GRB2 P62993 Growth factor receptor-bound protein 2 chr17 GO:0009314 Not Cancer Driver No 28 0.129 10 1 0.1 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0009314 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0009314 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRK1 GRK1 Q15835 Rhodopsin kinase GRK1 chr13 GO:0009314 Not Cancer Driver No 70 0.124 32 2 0.062 2
GRM6_ENST00000517717 GRM6 O15303 Metabotropic glutamate receptor 6 chr5 GO:0009314 Not Cancer Driver No 200 0.228 113 23 0.204 6
GTF2H5 GTF2H5 Q6ZYL4 General transcription factor IIH subunit 5 chr6 GO:0009314 Not Cancer Driver No 7 0.099 0 0 0.0 1
GUCA1A GUCA1A P43080 Guanylyl cyclase-activating protein 1 chr6 GO:0009314 Not Cancer Driver No 39 0.194 20 4 0.2 17
GUCY2F GUCY2F P51841 Retinal guanylyl cyclase 2 chrX GO:0009314 Not Cancer Driver No 230 0.208 88 15 0.17 0
H2AFX H2AX P16104 Histone H2AX chr11 GO:0009314 Not Cancer Driver No 20 0.14 68 10 0.147 0
HAMP_ENST00000222304 HAMP P81172 Hepcidin chr19 GO:0009314 Not Cancer Driver No 7 0.083 4 0 0.0 4
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0009314 Census Yes 118 0.143 435 51 0.117 0
HIST3H2A H2AW Q7L7L0 Histone H2A type 3 chr1 GO:0009314 Not Cancer Driver No 21 0.162 61 10 0.164 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 GO:0009314 Not Cancer Driver No 84 0.095 112 12 0.107 0
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 GO:0009314 Not Cancer Driver No 90 0.269 262 68 0.26 0
HRAS HRAS P01112 GTPase HRas chr11 GO:0009314 Census, Compendium Yes 107 0.566 16 4 0.25 18
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0009314 Not Cancer Driver No 96 0.197 122 26 0.213 0
HSF1 HSF1 Q00613 Heat shock factor protein 1 chr8 GO:0009314 Not Cancer Driver No 59 0.112 335 37 0.11 0
HSPA5 HSPA5 P11021 Endoplasmic reticulum chaperone BiP chr9 GO:0009314 Not Cancer Driver No 73 0.112 282 35 0.124 0
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 GO:0009314 Not Cancer Driver No 25 0.089 17 2 0.118 0
HYAL1_ENST00000395144 HYAL1 Q12794 Hyaluronidase-1 chr3 GO:0009314 Not Cancer Driver No 47 0.108 9 0 0.0 1
HYAL2_ENST00000357750 HYAL2 Q12891 Hyaluronidase-2 chr3 GO:0009314 Not Cancer Driver No 52 0.11 8 1 0.125 0
HYAL3 HYAL3 O43820 Hyaluronidase-3 chr3 GO:0009314 Not Cancer Driver No 48 0.115 10 0 0.0 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0009314 Not Cancer Driver No 14 0.104 52 7 0.135 0
IFI16_ENST00000295809 IFI16 Q16666 Gamma-interferon-inducible protein 16 chr1 GO:0009314 Not Cancer Driver No 155 0.197 419 90 0.215 0
IFT20_ENST00000395418 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 GO:0009314 Not Cancer Driver No 11 0.083 0 0 0.0 0
IKBIP_ENST00000342502 IKBIP Q70UQ0 Inhibitor of nuclear factor kappa-B kinase-interacting protein chr12 GO:0009314 Not Cancer Driver No 53 0.151 69 8 0.116 0
IL12B IL12B P29460 Interleukin-12 subunit beta chr5 GO:0009314 Not Cancer Driver No 48 0.146 42 2 0.048 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0009314 Not Cancer Driver No 30 0.111 35 6 0.171 0
IMPACT IMPACT Q9P2X3 Protein IMPACT chr18 GO:0009314 Not Cancer Driver No 49 0.153 84 12 0.143 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0009314 Compendium Yes 173 0.111 682 76 0.111 0
INTS7 INTS7 Q9NVH2 Integrator complex subunit 7 chr1 GO:0009314 Not Cancer Driver No 106 0.11 88 17 0.193 0
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0009314 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITGB6_ENST00000409872 ITGB6 P18564 Integrin beta-6 chr2 GO:0009314 Not Cancer Driver No 120 0.152 26 4 0.154 3
IVL IVL P07476 Involucrin chr1 GO:0009314 Not Cancer Driver No 115 0.197 585 115 0.197 0
KARS_ENST00000302445 KARS1 Q15046 Lysine--tRNA ligase chr16 GO:0009314 Not Cancer Driver No 88 0.147 160 15 0.094 12
KCNC1_ENST00000379472 KCNC1 P48547 Potassium voltage-gated channel subfamily C member 1 chr11 GO:0009314 Not Cancer Driver No 91 0.178 110 18 0.164 1
KCNC2 KCNC2 Q96PR1 Potassium voltage-gated channel subfamily C member 2 chr12 GO:0009314 Not Cancer Driver No 161 0.252 255 63 0.247 0
KDM1A_ENST00000356634 KDM1A O60341 Lysine-specific histone demethylase 1A chr1 GO:0009314 Not Cancer Driver No 67 0.079 291 28 0.096 3
KDM4D_ENST00000610872 KDM4D Q6B0I6 Lysine-specific demethylase 4D chr11 GO:0009314 Not Cancer Driver No 78 0.149 215 33 0.153 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0009314 Census, Compendium Yes 226 0.232 83 33 0.398 21
KRAS KRAS P01116 GTPase KRas chr12 GO:0009314 Census, Compendium Yes 788 4.169 7 2 0.286 27
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0009314 Not Cancer Driver No 134 0.147 63 10 0.159 2
LRRN4 LRRN4 Q8WUT4 Leucine-rich repeat neuronal protein 4 chr20 GO:0009314 Not Cancer Driver No 75 0.101 258 28 0.109 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0009314 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K4 MAP3K4 Q9Y6R4 Mitogen-activated protein kinase kinase kinase 4 chr6 GO:0009314 Not Cancer Driver No 261 0.162 520 86 0.165 0
MAPK13 MAPK13 O15264 Mitogen-activated protein kinase 13 chr6 GO:0009314 Not Cancer Driver No 51 0.14 50 15 0.3 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0009314 Not Cancer Driver No 39 0.108 25 1 0.04 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0009314 Not Cancer Driver No 39 0.123 0 0 0.0 5
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0009314 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0009314 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 GO:0009314 Not Cancer Driver No 94 0.197 358 76 0.212 0
MEN1 MEN1 O00255 Menin chr11 GO:0009314 Census, Compendium Yes 73 0.119 228 15 0.066 90
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0009314 Not Cancer Driver No 74 0.128 274 29 0.106 0
MFAP4_ENST00000299610 MFAP4 P55083 Microfibril-associated glycoprotein 4 chr17 GO:0009314 Not Cancer Driver No 35 0.137 0 0 0.0 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0009314 Not Cancer Driver No 189 0.252 40 17 0.425 4
MMP1 MMP1 P03956 Interstitial collagenase chr11 GO:0009314 Not Cancer Driver No 83 0.177 113 18 0.159 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0009314 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP3 MMP3 P08254 Stromelysin-1 chr11 GO:0009314 Not Cancer Driver No 99 0.208 66 14 0.212 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0009314 Not Cancer Driver No 129 0.182 124 26 0.21 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0009314 Census Yes 92 0.099 37 4 0.108 70
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 GO:0009314 Not Cancer Driver No 92 0.129 327 42 0.128 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0009314 Census, Compendium Yes 80 0.182 299 46 0.154 0
N4BP1 N4BP1 O75113 NEDD4-binding protein 1 chr16 GO:0009314 Not Cancer Driver No 108 0.121 432 58 0.134 0
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 GO:0009314 Not Cancer Driver No 44 0.125 90 11 0.122 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0009314 Not Cancer Driver No 150 0.114 711 79 0.111 0
NET1 NET1 Q7Z628 Neuroepithelial cell-transforming gene 1 protein chr10 GO:0009314 Not Cancer Driver No 60 0.101 294 37 0.126 0
NETO1 NETO1 Q8TDF5 Neuropilin and tolloid-like protein 1 chr18 GO:0009314 Not Cancer Driver No 186 0.349 103 33 0.32 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0009314 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0009314 Not Cancer Driver No 155 0.172 685 120 0.175 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0009314 Compendium Yes 353 0.126 1528 184 0.12 37
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 GO:0009314 Not Cancer Driver No 77 0.103 281 31 0.11 0
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 GO:0009314 Not Cancer Driver No 108 0.148 259 32 0.124 1
NPHP4 NPHP4 O75161 Nephrocystin-4 chr1 GO:0009314 Not Cancer Driver No 176 0.123 469 54 0.115 17
NPM1 NPM1 P06748 Nucleophosmin chr5 GO:0009314 Census, Compendium Yes 29 0.099 249 22 0.088 0
NPS NPS P0C0P6 Neuropeptide S chr10 GO:0009314 Not Cancer Driver No 27 0.303 5 2 0.4 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0009314 Not Cancer Driver No 47 0.118 118 9 0.076 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0009314 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR2E3 NR2E3 Q9Y5X4 Photoreceptor-specific nuclear receptor chr15 GO:0009314 Not Cancer Driver No 47 0.115 171 15 0.088 16
NR2F6 NR2F6 P10588 Nuclear receptor subfamily 2 group F member 6 chr19 GO:0009314 Not Cancer Driver No 25 0.062 70 4 0.057 0
NSMCE3 NSMCE3 Q96MG7 Non-structural maintenance of chromosomes element 3 homolog chr15 GO:0009314 Not Cancer Driver No 33 0.109 128 7 0.055 2
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0009314 Census, Compendium Yes 168 0.211 57 8 0.14 25
NUCKS1 NUCKS1 Q9H1E3 Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 chr1 GO:0009314 Not Cancer Driver No 30 0.123 243 30 0.123 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0009314 Not Cancer Driver No 37 0.107 71 12 0.169 0
OPN1LW OPN1LW P04000 Long-wave-sensitive opsin 1 chrX GO:0009314 Not Cancer Driver No 72 0.198 9 0 0.0 3
OPN1MW OPN1MW P04001 Medium-wave-sensitive opsin 1 chrX GO:0009314 Not Cancer Driver No 10 0.027 6 0 0.0 5
OPN1MW2 OPN1MW2 P0DN77 Medium-wave-sensitive opsin 2 chrX GO:0009314 Not Cancer Driver No 22 0.06 6 0 0.0 0
OPN1SW OPN1SW P03999 Short-wave-sensitive opsin 1 chr7 GO:0009314 Not Cancer Driver No 65 0.187 20 1 0.05 4
OPN3 OPN3 Q9H1Y3 Opsin-3 chr1 GO:0009314 Not Cancer Driver No 39 0.097 6 1 0.167 0
OPN4_ENST00000241891 OPN4 Q9UHM6 Melanopsin chr10 GO:0009314 Not Cancer Driver No 84 0.176 88 9 0.102 0
OPN5 OPN5 Q6U736 Opsin-5 chr6 GO:0009314 Not Cancer Driver No 65 0.184 0 0 0.0 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0009314 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0009314 Not Cancer Driver No 107 0.268 58 27 0.466 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0009314 Not Cancer Driver No 119 0.117 320 34 0.106 0
PBK_ENST00000301905 PBK Q96KB5 Lymphokine-activated killer T-cell-originated protein kinase chr8 GO:0009314 Not Cancer Driver No 23 0.071 92 6 0.065 0
PCNA PCNA P12004 Proliferating cell nuclear antigen chr20 GO:0009314 Not Cancer Driver No 30 0.115 22 3 0.136 1
PDC PDC P20941 Phosducin chr1 GO:0009314 Not Cancer Driver No 26 0.106 91 14 0.154 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0009314 Not Cancer Driver No 114 0.213 132 30 0.227 0
PDE6B PDE6B P35913 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta chr4 GO:0009314 Not Cancer Driver No 144 0.169 44 9 0.205 13
PDE6C PDE6C P51160 Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' chr10 GO:0009314 Not Cancer Driver No 127 0.148 87 17 0.195 8
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0009314 Not Cancer Driver No 109 0.408 142 62 0.437 0
PER1 PER1 O15534 Period circadian protein homolog 1 chr17 GO:0009314 Census Yes 160 0.124 948 116 0.122 0
PER2 PER2 O15055 Period circadian protein homolog 2 chr2 GO:0009314 Not Cancer Driver No 166 0.132 782 101 0.129 1
PER3_ENST00000361923 PER3 P56645 Period circadian protein homolog 3 chr1 GO:0009314 Not Cancer Driver No 170 0.142 710 100 0.141 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0009314 Census, Compendium Yes 154 0.213 268 61 0.228 2
PITPNM1_ENST00000534749 PITPNM1 O00562 Membrane-associated phosphatidylinositol transfer protein 1 chr11 GO:0009314 Not Cancer Driver No 157 0.126 477 69 0.145 0
PLEKHB1 PLEKHB1 Q9UF11 Pleckstrin homology domain-containing family B member 1 chr11 GO:0009314 Not Cancer Driver No 25 0.103 47 4 0.085 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0009314 Not Cancer Driver No 75 0.116 202 15 0.074 0
PML PML P29590 Protein PML chr15 GO:0009314 Census, Compendium Yes 112 0.127 312 34 0.109 0
PNKP PNKP Q96T60 Bifunctional polynucleotide phosphatase/kinase chr19 GO:0009314 Not Cancer Driver No 53 0.102 177 23 0.13 4
POLB POLB P06746 DNA polymerase beta chr8 GO:0009314 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0009314 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLH POLH Q9Y253 DNA polymerase eta chr6 GO:0009314 Not Cancer Driver No 72 0.101 291 20 0.069 10
POLK POLK Q9UBT6 DNA polymerase kappa chr5 GO:0009314 Not Cancer Driver No 97 0.111 293 36 0.123 0
PPID PPID Q08752 Peptidyl-prolyl cis-trans isomerase D chr4 GO:0009314 Not Cancer Driver No 36 0.097 94 9 0.096 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0009314 Census, Compendium Yes 54 0.089 370 32 0.086 0
PPP1CA_ENST00000376745 PPP1CA P62136 Serine/threonine-protein phosphatase PP1-alpha catalytic subunit chr11 GO:0009314 Not Cancer Driver No 38 0.115 27 6 0.222 0
PPP1CB_ENST00000358506 PPP1CB P62140 Serine/threonine-protein phosphatase PP1-beta catalytic subunit chr2 GO:0009314 Not Cancer Driver No 47 0.144 25 5 0.2 5
PPP1CC_ENST00000335007 PPP1CC P36873 Serine/threonine-protein phosphatase PP1-gamma catalytic subunit chr12 GO:0009314 Not Cancer Driver No 26 0.08 23 4 0.174 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0009314 Not Cancer Driver No 30 0.147 204 30 0.147 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0009314 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0009314 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0009314 Compendium Yes 79 0.117 43 9 0.209 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0009314 Not Cancer Driver No 538 0.13 421 61 0.145 2
PRPH2 PRPH2 P23942 Peripherin-2 chr6 GO:0009314 Not Cancer Driver No 54 0.156 35 2 0.057 44
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0009314 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0009314 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRK_ENST00000368215 PTPRK Q15262 Receptor-type tyrosine-protein phosphatase kappa chr6 GO:0009314 Census, Compendium Yes 292 0.203 302 57 0.189 0
RAD1 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:0009314 Not Cancer Driver No 29 0.103 4 1 0.25 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0009314 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0009314 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0009314 Not Cancer Driver No 34 0.087 135 7 0.052 0
RAD9B RAD9B Q6WBX8 Cell cycle checkpoint control protein RAD9B chr12 GO:0009314 Not Cancer Driver No 46 0.108 40 6 0.15 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0009314 Not Cancer Driver No 204 0.196 208 43 0.207 36
RBM4B_ENST00000310046 RBM4B Q9BQ04 RNA-binding protein 4B chr11 GO:0009314 Not Cancer Driver No 47 0.131 126 19 0.151 0
RBM4_ENST00000310092 RBM4 Q9BWF3 RNA-binding protein 4 chr11 GO:0009314 Not Cancer Driver No 40 0.11 129 12 0.093 0
RCVRN RCVRN P35243 Recoverin chr17 GO:0009314 Not Cancer Driver No 37 0.185 24 5 0.208 0
RDH13 RDH13 Q8NBN7 Retinol dehydrogenase 13 chr19 GO:0009314 Not Cancer Driver No 42 0.127 48 7 0.146 0
RELA RELA Q04206 Transcription factor p65 chr11 GO:0009314 Compendium Yes 75 0.136 400 48 0.12 0
RGR RGR P47804 RPE-retinal G protein-coupled receptor chr10 GO:0009314 Not Cancer Driver No 42 0.144 6 3 0.5 1
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0009314 Not Cancer Driver No 57 0.101 309 37 0.12 0
RGS9 RGS9 O75916 Regulator of G-protein signaling 9 chr17 GO:0009314 Not Cancer Driver No 138 0.205 240 65 0.271 1
RGS9BP RGS9BP Q6ZS82 Regulator of G-protein signaling 9-binding protein chr19 GO:0009314 Not Cancer Driver No 16 0.068 22 1 0.045 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0009314 Not Cancer Driver No 38 0.121 69 9 0.13 0
RHNO1 RHNO1 Q9BSD3 RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 chr12 GO:0009314 Not Cancer Driver No 26 0.109 193 21 0.109 0
RHO RHO P08100 Rhodopsin chr3 GO:0009314 Not Cancer Driver No 68 0.195 18 3 0.167 69
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0009314 Not Cancer Driver No 52 0.265 19 2 0.105 0
RIC8A_ENST00000526104 RIC8A Q9NPQ8 Synembryn-A chr11 GO:0009314 Not Cancer Driver No 63 0.119 163 23 0.141 0
ROM1 ROM1 Q03395 Rod outer segment membrane protein 1 chr11 GO:0009314 Not Cancer Driver No 41 0.117 26 4 0.154 0
RP1 RP1 P56715 Oxygen-regulated protein 1 chr8 GO:0009314 Not Cancer Driver No 737 0.342 1215 441 0.363 6
RPE65 RPE65 Q16518 Retinoid isomerohydrolase chr1 GO:0009314 Not Cancer Driver No 109 0.205 10 1 0.1 44
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0009314 Not Cancer Driver No 16 0.11 114 13 0.114 0
RRH RRH O14718 Visual pigment-like receptor peropsin chr4 GO:0009314 Not Cancer Driver No 34 0.101 15 0 0.0 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0009314 Not Cancer Driver No 62 0.134 100 13 0.13 0
SAG SAG P10523 S-arrestin chr2 GO:0009314 Not Cancer Driver No 70 0.173 102 11 0.108 0
SCARA3 SCARA3 Q6AZY7 Scavenger receptor class A member 3 chr8 GO:0009314 Not Cancer Driver No 80 0.132 230 29 0.126 0
SDE2 SDE2 Q6IQ49 Replication stress response regulator SDE2 chr1 GO:0009314 Not Cancer Driver No 56 0.124 290 35 0.121 0
SDF4 SDF4 Q9BRK5 45 kDa calcium-binding protein chr1 GO:0009314 Not Cancer Driver No 48 0.133 187 30 0.16 0
SEMA5B_ENST00000616742 SEMA5B Q9P283 Semaphorin-5B chr3 GO:0009314 Not Cancer Driver No 229 0.199 162 16 0.099 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0009314 Not Cancer Driver No 40 0.127 39 7 0.179 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0009314 Not Cancer Driver No 47 0.159 1 0 0.0 0
SIK1 SIK1 P57059 Serine/threonine-protein kinase SIK1 chr21 GO:0009314 Not Cancer Driver No 80 0.102 330 30 0.091 3
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0009314 Not Cancer Driver No 70 0.094 435 31 0.071 0
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0009314 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC24A1 SLC24A1 O60721 Sodium/potassium/calcium exchanger 1 chr15 GO:0009314 Not Cancer Driver No 105 0.096 595 53 0.089 0
SLC24A2 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0009314 Not Cancer Driver No 120 0.182 144 24 0.167 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0009314 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0009314 Not Cancer Driver No 70 0.14 15 2 0.133 0
SMC1A SMC1A Q14683 Structural maintenance of chromosomes protein 1A chrX GO:0009314 Census, Compendium Yes 200 0.162 717 114 0.159 21
SMPD1 SMPD1 P17405 Sphingomyelin phosphodiesterase chr11 GO:0009314 Not Cancer Driver No 93 0.147 51 4 0.078 111
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0009314 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0009314 Not Cancer Driver No 32 0.144 25 5 0.2 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0009314 Not Cancer Driver No 101 0.11 329 20 0.061 0
ST20_ENST00000562759 ST20 Q9HBF5 Suppressor of tumorigenicity 20 protein chr15 GO:0009314 Not Cancer Driver No 17 0.215 0 0 0.0 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0009314 Census, Compendium Yes 75 0.173 135 14 0.104 9
SWI5 SWI5 Q1ZZU3 DNA repair protein SWI5 homolog chr9 GO:0009314 Not Cancer Driver No 45 0.191 128 35 0.273 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0009314 Not Cancer Driver No 153 0.114 830 90 0.108 2
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0009314 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TANC1 TANC1 Q9C0D5 Protein TANC1 chr2 GO:0009314 Not Cancer Driver No 237 0.127 906 101 0.111 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0009314 Not Cancer Driver No 42 0.099 302 26 0.086 0
TENT2_ENST00000428308 TENT2 Q6PIY7 Poly(A) RNA polymerase GLD2 chr5 GO:0009314 Not Cancer Driver No 65 0.134 75 15 0.2 0
THBD THBD P07204 Thrombomodulin chr20 GO:0009314 Not Cancer Driver No 39 0.068 51 3 0.059 9
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0009314 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMP1 TIMP1 P01033 Metalloproteinase inhibitor 1 chrX GO:0009314 Not Cancer Driver No 25 0.121 0 0 0.0 0
TLK2 TLK2 Q86UE8 Serine/threonine-protein kinase tousled-like 2 chr17 GO:0009314 Not Cancer Driver No 120 0.155 436 58 0.133 5
TMEM109 TMEM109 Q9BVC6 Transmembrane protein 109 chr11 GO:0009314 Not Cancer Driver No 39 0.16 7 0 0.0 0
TMEM161A TMEM161A Q9NX61 Transmembrane protein 161A chr19 GO:0009314 Not Cancer Driver No 49 0.102 22 8 0.364 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0009314 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF11A TNFRSF11A Q9Y6Q6 Tumor necrosis factor receptor superfamily member 11A chr18 GO:0009314 Not Cancer Driver No 70 0.114 285 33 0.116 0
TNKS1BP1 TNKS1BP1 Q9C0C2 182 kDa tankyrase-1-binding protein chr11 GO:0009314 Not Cancer Driver No 221 0.128 1712 219 0.128 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0009314 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0009314 Not Cancer Driver No 32 0.133 134 20 0.149 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0009314 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0009314 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0009314 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM13_ENST00000378182 TRIM13 O60858 E3 ubiquitin-protein ligase TRIM13 chr13 GO:0009314 Not Cancer Driver No 53 0.13 1 0 0.0 0
TRPC3_ENST00000264811 TRPC3 Q13507 Short transient receptor potential channel 3 chr4 GO:0009314 Not Cancer Driver No 200 0.239 23 2 0.087 1
TSPYL5 TSPYL5 Q86VY4 Testis-specific Y-encoded-like protein 5 chr8 GO:0009314 Not Cancer Driver No 92 0.221 257 61 0.237 0
TTC36 TTC36 A6NLP5 Tetratricopeptide repeat protein 36 chr11 GO:0009314 Not Cancer Driver No 13 0.069 98 12 0.122 0
TULP1 TULP1 O00294 Tubby-related protein 1 chr6 GO:0009314 Not Cancer Driver No 101 0.186 377 76 0.202 12
TXN TXN P10599 Thioredoxin chr9 GO:0009314 Not Cancer Driver No 6 0.057 0 0 0.0 0
TYR TYR P14679 Tyrosinase chr11 GO:0009314 Not Cancer Driver No 156 0.295 52 15 0.288 111
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0009314 Not Cancer Driver No 20 0.083 89 4 0.045 1
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 GO:0009314 Not Cancer Driver No 88 0.145 213 39 0.183 0
USP28 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 GO:0009314 Not Cancer Driver No 151 0.14 311 25 0.08 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0009314 Not Cancer Driver No 137 0.1 425 39 0.092 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0009314 Census, Compendium Yes 164 0.115 373 41 0.11 2
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0009314 Census Yes 27 0.099 121 13 0.107 5
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0009314 Census, Compendium Yes 88 0.094 479 48 0.1 2
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0009314 Not Cancer Driver No 36 0.129 9 1 0.111 2
XRCC4 XRCC4 Q13426 DNA repair protein XRCC4 chr5 GO:0009314 Not Cancer Driver No 47 0.14 171 31 0.181 3
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0009314 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0009314 Not Cancer Driver No 66 0.108 140 12 0.086 0
XRRA1 XRRA1 Q6P2D8 X-ray radiation resistance-associated protein 1 chr11 GO:0009314 Not Cancer Driver No 86 0.109 316 31 0.098 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0009314 Not Cancer Driver No 51 0.101 489 49 0.1 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0009314 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0009314 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0009314 Not Cancer Driver No 67 0.141 23 0 0.0 3