Total number of protein in "GO:0009187" GO term: 39
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCY1 | ADCY1 | Q08828 | Adenylate cyclase type 1 | chr7 | GO:0009187 | Not Cancer Driver | No | 244 | 0.218 | 99 | 19 | 0.192 | 0 |
| ADCY10 | ADCY10 | Q96PN6 | Adenylate cyclase type 10 | chr1 | GO:0009187 | Not Cancer Driver | No | 249 | 0.155 | 24 | 4 | 0.167 | 0 |
| ADCY2 | ADCY2 | Q08462 | Adenylate cyclase type 2 | chr5 | GO:0009187 | Not Cancer Driver | No | 303 | 0.278 | 95 | 24 | 0.253 | 0 |
| ADCY3_ENST00000260600 | ADCY3 | O60266 | Adenylate cyclase type 3 | chr2 | GO:0009187 | Not Cancer Driver | No | 135 | 0.118 | 185 | 18 | 0.097 | 0 |
| ADCY4_ENST00000554068 | ADCY4 | Q8NFM4 | Adenylate cyclase type 4 | chr14 | GO:0009187 | Not Cancer Driver | No | 137 | 0.127 | 94 | 23 | 0.245 | 0 |
| ADCY5 | ADCY5 | O95622 | Adenylate cyclase type 5 | chr3 | GO:0009187 | Not Cancer Driver | No | 234 | 0.186 | 268 | 23 | 0.086 | 2 |
| ADCY6 | ADCY6 | O43306 | Adenylate cyclase type 6 | chr12 | GO:0009187 | Not Cancer Driver | No | 144 | 0.123 | 147 | 17 | 0.116 | 1 |
| ADCY7_ENST00000254235 | ADCY7 | P51828 | Adenylate cyclase type 7 | chr16 | GO:0009187 | Not Cancer Driver | No | 144 | 0.133 | 121 | 17 | 0.14 | 0 |
| ADCY8 | ADCY8 | P40145 | Adenylate cyclase type 8 | chr8 | GO:0009187 | Not Cancer Driver | No | 419 | 0.335 | 215 | 38 | 0.177 | 0 |
| ADCY9 | ADCY9 | O60503 | Adenylate cyclase type 9 | chr16 | GO:0009187 | Not Cancer Driver | No | 195 | 0.144 | 271 | 42 | 0.155 | 0 |
| AMPD2_ENST00000528667 | AMPD2 | Q01433 | AMP deaminase 2 | chr1 | GO:0009187 | Not Cancer Driver | No | 93 | 0.106 | 275 | 27 | 0.098 | 3 |
| CNP | CNP | P09543 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | chr17 | GO:0009187 | Not Cancer Driver | No | 36 | 0.086 | 71 | 2 | 0.028 | 0 |
| EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0009187 | Compendium | Yes | 171 | 0.175 | 187 | 39 | 0.209 | 3 |
| GUCY1A1_ENST00000513574 | GUCY1A1 | Q02108 | Guanylate cyclase soluble subunit alpha-1 | chr4 | GO:0009187 | Not Cancer Driver | No | 181 | 0.262 | 54 | 8 | 0.148 | 0 |
| GUCY1A2_ENST00000526355 | GUCY1A2 | P33402 | Guanylate cyclase soluble subunit alpha-2 | chr11 | GO:0009187 | Not Cancer Driver | No | 191 | 0.261 | 187 | 48 | 0.257 | 0 |
| GUCY1B1_ENST00000264424 | GUCY1B1 | Q02153 | Guanylate cyclase soluble subunit beta-1 | chr4 | GO:0009187 | Not Cancer Driver | No | 103 | 0.166 | 83 | 20 | 0.241 | 0 |
| GUCY2C | GUCY2C | P25092 | Guanylyl cyclase C | chr12 | GO:0009187 | Not Cancer Driver | No | 209 | 0.195 | 51 | 7 | 0.137 | 2 |
| GUCY2D | GUCY2D | Q02846 | Retinal guanylyl cyclase 1 | chr17 | GO:0009187 | Not Cancer Driver | No | 138 | 0.125 | 205 | 34 | 0.166 | 32 |
| GUCY2F | GUCY2F | P51841 | Retinal guanylyl cyclase 2 | chrX | GO:0009187 | Not Cancer Driver | No | 230 | 0.208 | 88 | 15 | 0.17 | 0 |
| NPPA | NPPA | P01160 | Natriuretic peptides A | chr1 | GO:0009187 | Not Cancer Driver | No | 32 | 0.212 | 71 | 14 | 0.197 | 1 |
| NPPB | NPPB | P16860 | Natriuretic peptides B | chr1 | GO:0009187 | Not Cancer Driver | No | 31 | 0.231 | 104 | 28 | 0.269 | 0 |
| NPPC | NPPC | P23582 | C-type natriuretic peptide | chr2 | GO:0009187 | Not Cancer Driver | No | 10 | 0.079 | 82 | 6 | 0.073 | 0 |
| NPR1 | NPR1 | P16066 | Atrial natriuretic peptide receptor 1 | chr1 | GO:0009187 | Not Cancer Driver | No | 141 | 0.133 | 78 | 16 | 0.205 | 0 |
| NPR2 | NPR2 | P20594 | Atrial natriuretic peptide receptor 2 | chr9 | GO:0009187 | Not Cancer Driver | No | 144 | 0.138 | 89 | 18 | 0.202 | 20 |
| PDE10A_ENST00000366882 | PDE10A | Q9Y233 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | chr6 | GO:0009187 | Not Cancer Driver | No | 198 | 0.254 | 79 | 21 | 0.266 | 4 |
| PDE2A | PDE2A | O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | chr11 | GO:0009187 | Not Cancer Driver | No | 137 | 0.146 | 99 | 7 | 0.071 | 0 |
| PDE4A | PDE4A | P27815 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | chr19 | GO:0009187 | Not Cancer Driver | No | 123 | 0.139 | 559 | 67 | 0.12 | 0 |
| PDE4B | PDE4B | Q07343 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | chr1 | GO:0009187 | Not Cancer Driver | No | 119 | 0.162 | 363 | 42 | 0.116 | 0 |
| PDE4C | PDE4C | Q08493 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C | chr19 | GO:0009187 | Not Cancer Driver | No | 122 | 0.171 | 362 | 61 | 0.169 | 0 |
| PDE4D | PDE4D | Q08499 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | chr5 | GO:0009187 | Not Cancer Driver | No | 86 | 0.106 | 464 | 54 | 0.116 | 12 |
| PDE5A | PDE5A | O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | chr4 | GO:0009187 | Not Cancer Driver | No | 113 | 0.129 | 163 | 23 | 0.141 | 0 |
| PDE7A | PDE7A | Q13946 | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | chr8 | GO:0009187 | Not Cancer Driver | No | 49 | 0.102 | 30 | 7 | 0.233 | 0 |
| PDE7B | PDE7B | Q9NP56 | cAMP-specific 3',5'-cyclic phosphodiesterase 7B | chr6 | GO:0009187 | Not Cancer Driver | No | 74 | 0.164 | 47 | 7 | 0.149 | 0 |
| PDE8A_ENST00000394553 | PDE8A | O60658 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | chr15 | GO:0009187 | Not Cancer Driver | No | 78 | 0.094 | 187 | 17 | 0.091 | 0 |
| PDE8B | PDE8B | O95263 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B | chr5 | GO:0009187 | Not Cancer Driver | No | 144 | 0.163 | 208 | 19 | 0.091 | 1 |
| PDE9A | PDE9A | O76083 | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | chr21 | GO:0009187 | Not Cancer Driver | No | 91 | 0.153 | 160 | 34 | 0.212 | 0 |
| PTH | PTH | P01270 | Parathyroid hormone | chr11 | GO:0009187 | Not Cancer Driver | No | 19 | 0.165 | 60 | 10 | 0.167 | 2 |
| PTHLH_ENST00000539239 | PTHLH | P12272 | Parathyroid hormone-related protein | chr12 | GO:0009187 | Not Cancer Driver | No | 44 | 0.249 | 132 | 40 | 0.303 | 2 |
| RORA_ENST00000335670 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0009187 | Not Cancer Driver | No | 57 | 0.109 | 182 | 17 | 0.093 | 4 |