Total number of protein in "GO:0009166" GO term: 71
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCD1 | ABCD1 | P33897 | ATP-binding cassette sub-family D member 1 | chrX | GO:0009166 | Not Cancer Driver | No | 106 | 0.142 | 75 | 5 | 0.067 | 138 |
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | GO:0009166 | Not Cancer Driver | No | 45 | 0.105 | 32 | 1 | 0.031 | 10 |
| ACOT7 | ACOT7 | O00154 | Cytosolic acyl coenzyme A thioester hydrolase | chr1 | GO:0009166 | Not Cancer Driver | No | 43 | 0.113 | 77 | 16 | 0.208 | 0 |
| ADA | ADA | P00813 | Adenosine deaminase | chr20 | GO:0009166 | Not Cancer Driver | No | 50 | 0.138 | 44 | 9 | 0.205 | 27 |
| AMPD3_ENST00000529507 | AMPD3 | Q01432 | AMP deaminase 3 | chr11 | GO:0009166 | Not Cancer Driver | No | 132 | 0.172 | 207 | 38 | 0.184 | 10 |
| CNP | CNP | P09543 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | chr17 | GO:0009166 | Not Cancer Driver | No | 36 | 0.086 | 71 | 2 | 0.028 | 0 |
| DCTPP1 | DCTPP1 | Q9H773 | dCTP pyrophosphatase 1 | chr16 | GO:0009166 | Not Cancer Driver | No | 14 | 0.082 | 88 | 9 | 0.102 | 0 |
| DERA | DERA | Q9Y315 | Deoxyribose-phosphate aldolase | chr12 | GO:0009166 | Not Cancer Driver | No | 33 | 0.104 | 2 | 0 | 0.0 | 0 |
| DNPH1 | DNPH1 | O43598 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | chr6 | GO:0009166 | Not Cancer Driver | No | 15 | 0.086 | 49 | 3 | 0.061 | 0 |
| DPYD | DPYD | Q12882 | Dihydropyrimidine dehydrogenase [NADP(+)] | chr1 | GO:0009166 | Not Cancer Driver | No | 303 | 0.296 | 77 | 23 | 0.299 | 3 |
| DPYS | DPYS | Q14117 | Dihydropyrimidinase | chr8 | GO:0009166 | Not Cancer Driver | No | 148 | 0.285 | 103 | 28 | 0.272 | 5 |
| DUT | DUT | P33316 | Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial | chr15 | GO:0009166 | Not Cancer Driver | No | 19 | 0.075 | 128 | 8 | 0.062 | 0 |
| ENTPD4 | ENTPD4 | Q9Y227 | Ectonucleoside triphosphate diphosphohydrolase 4 | chr8 | GO:0009166 | Not Cancer Driver | No | 67 | 0.109 | 26 | 2 | 0.077 | 0 |
| ENTPD7 | ENTPD7 | Q9NQZ7 | Ectonucleoside triphosphate diphosphohydrolase 7 | chr10 | GO:0009166 | Not Cancer Driver | No | 90 | 0.149 | 26 | 3 | 0.115 | 0 |
| FHIT_ENST00000492590 | FHIT | P49789 | Bis(5'-adenosyl)-triphosphatase | chr3 | GO:0009166 | Census, Compendium | Yes | 35 | 0.238 | 45 | 9 | 0.2 | 0 |
| FITM2 | FITM2 | Q8N6M3 | Acyl-coenzyme A diphosphatase FITM2 | chr20 | GO:0009166 | Not Cancer Driver | No | 28 | 0.107 | 0 | 0 | 0.0 | 1 |
| GDA_ENST00000358399 | GDA | Q9Y2T3 | Guanine deaminase | chr9 | GO:0009166 | Not Cancer Driver | No | 86 | 0.189 | 22 | 7 | 0.318 | 0 |
| HPRT1 | HPRT1 | P00492 | Hypoxanthine-guanine phosphoribosyltransferase | chrX | GO:0009166 | Not Cancer Driver | No | 22 | 0.101 | 3 | 0 | 0.0 | 62 |
| ITPA | ITPA | Q9BY32 | Inosine triphosphate pyrophosphatase | chr20 | GO:0009166 | Not Cancer Driver | No | 21 | 0.108 | 10 | 1 | 0.1 | 1 |
| MBD4 | MBD4 | O95243 | Methyl-CpG-binding domain protein 4 | chr3 | GO:0009166 | Not Cancer Driver | No | 61 | 0.105 | 268 | 27 | 0.101 | 0 |
| MLYCD | MLYCD | O95822 | Malonyl-CoA decarboxylase, mitochondrial | chr16 | GO:0009166 | Not Cancer Driver | No | 41 | 0.083 | 82 | 0 | 0.0 | 0 |
| NEIL1_ENST00000564784 | NEIL1 | Q96FI4 | Endonuclease 8-like 1 | chr15 | GO:0009166 | Not Cancer Driver | No | 41 | 0.105 | 165 | 14 | 0.085 | 0 |
| NEIL2 | NEIL2 | Q969S2 | Endonuclease 8-like 2 | chr8 | GO:0009166 | Not Cancer Driver | No | 31 | 0.093 | 145 | 14 | 0.097 | 0 |
| NT5C | NT5C | Q8TCD5 | 5'(3')-deoxyribonucleotidase, cytosolic type | chr17 | GO:0009166 | Not Cancer Driver | No | 19 | 0.095 | 4 | 0 | 0.0 | 0 |
| NT5C1A | NT5C1A | Q9BXI3 | Cytosolic 5'-nucleotidase 1A | chr1 | GO:0009166 | Not Cancer Driver | No | 86 | 0.234 | 95 | 16 | 0.168 | 0 |
| NT5C1B | NT5C1B | Q96P26 | Cytosolic 5'-nucleotidase 1B | chr2 | GO:0009166 | Not Cancer Driver | No | 136 | 0.223 | 253 | 58 | 0.229 | 0 |
| NT5C2_ENST00000404739 | NT5C2 | P49902 | Cytosolic purine 5'-nucleotidase | chr10 | GO:0009166 | Census | Yes | 57 | 0.102 | 85 | 8 | 0.094 | 0 |
| NT5E | NT5E | P21589 | 5'-nucleotidase | chr6 | GO:0009166 | Not Cancer Driver | No | 61 | 0.106 | 26 | 2 | 0.077 | 1 |
| NT5M | NT5M | Q9NPB1 | 5'(3')-deoxyribonucleotidase, mitochondrial | chr17 | GO:0009166 | Not Cancer Driver | No | 20 | 0.088 | 0 | 0 | 0.0 | 0 |
| NTHL1 | NTHL1 | P78549 | Endonuclease III-like protein 1 | chr16 | GO:0009166 | Census | Yes | 38 | 0.122 | 147 | 18 | 0.122 | 0 |
| NUDT10_ENST00000356450 | NUDT10 | Q8NFP7 | Diphosphoinositol polyphosphate phosphohydrolase 3-alpha | chrX | GO:0009166 | Not Cancer Driver | No | 29 | 0.177 | 68 | 8 | 0.118 | 0 |
| NUDT11 | NUDT11 | Q96G61 | Diphosphoinositol polyphosphate phosphohydrolase 3-beta | chrX | GO:0009166 | Not Cancer Driver | No | 30 | 0.183 | 65 | 13 | 0.2 | 0 |
| NUDT12 | NUDT12 | Q9BQG2 | NAD-capped RNA hydrolase NUDT12 | chr5 | GO:0009166 | Not Cancer Driver | No | 65 | 0.141 | 11 | 2 | 0.182 | 0 |
| NUDT13 | NUDT13 | Q86X67 | NAD(P)H pyrophosphatase NUDT13, mitochondrial | chr10 | GO:0009166 | Not Cancer Driver | No | 40 | 0.114 | 19 | 0 | 0.0 | 0 |
| NUDT15 | NUDT15 | Q9NV35 | Nucleotide triphosphate diphosphatase NUDT15 | chr13 | GO:0009166 | Not Cancer Driver | No | 24 | 0.146 | 37 | 3 | 0.081 | 0 |
| NUDT16_ENST00000521288 | NUDT16 | Q96DE0 | U8 snoRNA-decapping enzyme | chr3 | GO:0009166 | Not Cancer Driver | No | 29 | 0.149 | 8 | 1 | 0.125 | 0 |
| NUDT17 | NUDT17 | P0C025 | Nucleoside diphosphate-linked moiety X motif 17 | chr1 | GO:0009166 | Not Cancer Driver | No | 33 | 0.101 | 91 | 15 | 0.165 | 0 |
| NUDT18 | NUDT18 | Q6ZVK8 | 8-oxo-dGDP phosphatase NUDT18 | chr8 | GO:0009166 | Not Cancer Driver | No | 22 | 0.068 | 39 | 3 | 0.077 | 0 |
| NUDT19 | NUDT19 | A8MXV4 | Acyl-coenzyme A diphosphatase NUDT19 | chr19 | GO:0009166 | Not Cancer Driver | No | 27 | 0.072 | 131 | 5 | 0.038 | 0 |
| NUDT3 | NUDT3 | O95989 | Diphosphoinositol polyphosphate phosphohydrolase 1 | chr6 | GO:0009166 | Not Cancer Driver | No | 22 | 0.128 | 38 | 5 | 0.132 | 0 |
| NUDT4B | NUDT4B | A0A024RBG1 | Diphosphoinositol polyphosphate phosphohydrolase NUDT4B | chr1 | GO:0009166 | Not Cancer Driver | No | 2 | 0.011 | 53 | 0 | 0.0 | 0 |
| NUDT4_ENST00000415493 | NUDT4 | Q9NZJ9 | Diphosphoinositol polyphosphate phosphohydrolase 2 | chr12 | GO:0009166 | Not Cancer Driver | No | 20 | 0.111 | 53 | 9 | 0.17 | 0 |
| NUDT7 | NUDT7 | P0C024 | Peroxisomal coenzyme A diphosphatase NUDT7 | chr16 | GO:0009166 | Not Cancer Driver | No | 45 | 0.189 | 42 | 4 | 0.095 | 0 |
| NUDT8 | NUDT8 | Q8WV74 | Mitochondrial coenzyme A diphosphatase NUDT8 | chr11 | GO:0009166 | Not Cancer Driver | No | 22 | 0.093 | 69 | 10 | 0.145 | 0 |
| NUDT9 | NUDT9 | Q9BW91 | ADP-ribose pyrophosphatase, mitochondrial | chr4 | GO:0009166 | Not Cancer Driver | No | 27 | 0.077 | 177 | 16 | 0.09 | 0 |
| OGG1_ENST00000344629 | OGG1 | O15527 | N-glycosylase/DNA lyase | chr3 | GO:0009166 | Not Cancer Driver | No | 37 | 0.107 | 71 | 12 | 0.169 | 0 |
| PDE10A_ENST00000366882 | PDE10A | Q9Y233 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | chr6 | GO:0009166 | Not Cancer Driver | No | 198 | 0.254 | 79 | 21 | 0.266 | 4 |
| PDE2A | PDE2A | O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | chr11 | GO:0009166 | Not Cancer Driver | No | 137 | 0.146 | 99 | 7 | 0.071 | 0 |
| PDE4A | PDE4A | P27815 | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | chr19 | GO:0009166 | Not Cancer Driver | No | 123 | 0.139 | 559 | 67 | 0.12 | 0 |
| PDE4B | PDE4B | Q07343 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | chr1 | GO:0009166 | Not Cancer Driver | No | 119 | 0.162 | 363 | 42 | 0.116 | 0 |
| PDE4C | PDE4C | Q08493 | cAMP-specific 3',5'-cyclic phosphodiesterase 4C | chr19 | GO:0009166 | Not Cancer Driver | No | 122 | 0.171 | 362 | 61 | 0.169 | 0 |
| PDE4D | PDE4D | Q08499 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | chr5 | GO:0009166 | Not Cancer Driver | No | 86 | 0.106 | 464 | 54 | 0.116 | 12 |
| PDE5A | PDE5A | O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | chr4 | GO:0009166 | Not Cancer Driver | No | 113 | 0.129 | 163 | 23 | 0.141 | 0 |
| PDE7A | PDE7A | Q13946 | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | chr8 | GO:0009166 | Not Cancer Driver | No | 49 | 0.102 | 30 | 7 | 0.233 | 0 |
| PDE7B | PDE7B | Q9NP56 | cAMP-specific 3',5'-cyclic phosphodiesterase 7B | chr6 | GO:0009166 | Not Cancer Driver | No | 74 | 0.164 | 47 | 7 | 0.149 | 0 |
| PDE8A_ENST00000394553 | PDE8A | O60658 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A | chr15 | GO:0009166 | Not Cancer Driver | No | 78 | 0.094 | 187 | 17 | 0.091 | 0 |
| PDE8B | PDE8B | O95263 | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B | chr5 | GO:0009166 | Not Cancer Driver | No | 144 | 0.163 | 208 | 19 | 0.091 | 1 |
| PDE9A | PDE9A | O76083 | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | chr21 | GO:0009166 | Not Cancer Driver | No | 91 | 0.153 | 160 | 34 | 0.212 | 0 |
| PNP | PNP | P00491 | Purine nucleoside phosphorylase | chr14 | GO:0009166 | Not Cancer Driver | No | 38 | 0.131 | 29 | 2 | 0.069 | 5 |
| PRTFDC1 | PRTFDC1 | Q9NRG1 | Phosphoribosyltransferase domain-containing protein 1 | chr10 | GO:0009166 | Not Cancer Driver | No | 29 | 0.129 | 3 | 0 | 0.0 | 0 |
| SAMHD1 | SAMHD1 | Q9Y3Z3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | chr20 | GO:0009166 | Not Cancer Driver | No | 104 | 0.166 | 91 | 14 | 0.154 | 13 |
| SARM1 | SARM1 | Q6SZW1 | NAD(+) hydrolase SARM1 | chr17 | GO:0009166 | Not Cancer Driver | No | 36 | 0.05 | 80 | 4 | 0.05 | 0 |
| SMUG1 | SMUG1 | Q53HV7 | Single-strand selective monofunctional uracil DNA glycosylase | chr12 | GO:0009166 | Not Cancer Driver | No | 33 | 0.122 | 46 | 2 | 0.043 | 0 |
| TDG | TDG | Q13569 | G/T mismatch-specific thymine DNA glycosylase | chr12 | GO:0009166 | Not Cancer Driver | No | 75 | 0.183 | 185 | 31 | 0.168 | 0 |
| TYMP_ENST00000395680 | TYMP | P19971 | Thymidine phosphorylase | chr22 | GO:0009166 | Not Cancer Driver | No | 28 | 0.058 | 143 | 7 | 0.049 | 5 |
| UNG | UNG | P13051 | Uracil-DNA glycosylase | chr12 | GO:0009166 | Not Cancer Driver | No | 34 | 0.109 | 96 | 13 | 0.135 | 1 |
| UPB1 | UPB1 | Q9UBR1 | Beta-ureidopropionase | chr22 | GO:0009166 | Not Cancer Driver | No | 66 | 0.172 | 22 | 7 | 0.318 | 8 |
| UPP1_ENST00000395564 | UPP1 | Q16831 | Uridine phosphorylase 1 | chr7 | GO:0009166 | Not Cancer Driver | No | 47 | 0.152 | 13 | 3 | 0.231 | 0 |
| UPP2_ENST00000005756 | UPP2 | O95045 | Uridine phosphorylase 2 | chr2 | GO:0009166 | Not Cancer Driver | No | 55 | 0.174 | 5 | 1 | 0.2 | 0 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0009166 | Not Cancer Driver | No | 88 | 0.109 | 186 | 16 | 0.086 | 16 |
| XDH | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0009166 | Not Cancer Driver | No | 279 | 0.209 | 134 | 24 | 0.179 | 1 |