Total number of protein in "GO:0009063" GO term: 102
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AADAT_ENST00000515480 | AADAT | Q8N5Z0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | chr4 | GO:0009063 | Not Cancer Driver | No | 48 | 0.113 | 71 | 10 | 0.141 | 0 |
| AASS | AASS | Q9UDR5 | Alpha-aminoadipic semialdehyde synthase, mitochondrial | chr7 | GO:0009063 | Not Cancer Driver | No | 161 | 0.174 | 18 | 3 | 0.167 | 0 |
| ABAT_ENST00000268251 | ABAT | P80404 | 4-aminobutyrate aminotransferase, mitochondrial | chr16 | GO:0009063 | Not Cancer Driver | No | 84 | 0.168 | 28 | 5 | 0.179 | 1 |
| ACAD8 | ACAD8 | Q9UKU7 | Isobutyryl-CoA dehydrogenase, mitochondrial | chr11 | GO:0009063 | Not Cancer Driver | No | 55 | 0.133 | 13 | 1 | 0.077 | 9 |
| ACADSB | ACADSB | P45954 | Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial | chr10 | GO:0009063 | Not Cancer Driver | No | 59 | 0.137 | 16 | 3 | 0.188 | 1 |
| ACAT1 | ACAT1 | P24752 | Acetyl-CoA acetyltransferase, mitochondrial | chr11 | GO:0009063 | Not Cancer Driver | No | 45 | 0.105 | 32 | 1 | 0.031 | 10 |
| ACMSD | ACMSD | Q8TDX5 | 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase | chr2 | GO:0009063 | Not Cancer Driver | No | 65 | 0.193 | 9 | 2 | 0.222 | 0 |
| ADHFE1 | ADHFE1 | Q8IWW8 | Hydroxyacid-oxoacid transhydrogenase, mitochondrial | chr8 | GO:0009063 | Not Cancer Driver | No | 63 | 0.135 | 37 | 8 | 0.216 | 0 |
| AFMID_ENST00000409257 | AFMID | Q63HM1 | Kynurenine formamidase | chr17 | GO:0009063 | Not Cancer Driver | No | 46 | 0.152 | 12 | 1 | 0.083 | 0 |
| AGXT | AGXT | P21549 | Alanine--glyoxylate aminotransferase | chr2 | GO:0009063 | Not Cancer Driver | No | 56 | 0.143 | 20 | 0 | 0.0 | 40 |
| AGXT2 | AGXT2 | Q9BYV1 | Alanine--glyoxylate aminotransferase 2, mitochondrial | chr5 | GO:0009063 | Not Cancer Driver | No | 136 | 0.265 | 11 | 5 | 0.455 | 0 |
| ALDH4A1 | ALDH4A1 | P30038 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | chr1 | GO:0009063 | Not Cancer Driver | No | 63 | 0.112 | 46 | 9 | 0.196 | 1 |
| ALDH5A1_ENST00000357578 | ALDH5A1 | P51649 | Succinate-semialdehyde dehydrogenase, mitochondrial | chr6 | GO:0009063 | Not Cancer Driver | No | 64 | 0.12 | 31 | 7 | 0.226 | 12 |
| ALDH6A1 | ALDH6A1 | Q02252 | Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial | chr14 | GO:0009063 | Not Cancer Driver | No | 54 | 0.101 | 83 | 11 | 0.133 | 1 |
| ALDH8A1 | ALDH8A1 | Q9H2A2 | 2-aminomuconic semialdehyde dehydrogenase | chr6 | GO:0009063 | Not Cancer Driver | No | 107 | 0.22 | 40 | 6 | 0.15 | 0 |
| AMDHD1 | AMDHD1 | Q96NU7 | Probable imidazolonepropionase | chr12 | GO:0009063 | Not Cancer Driver | No | 72 | 0.169 | 23 | 5 | 0.217 | 0 |
| AMT | AMT | P48728 | Aminomethyltransferase, mitochondrial | chr3 | GO:0009063 | Not Cancer Driver | No | 37 | 0.092 | 33 | 6 | 0.182 | 11 |
| ARG1_ENST00000368087 | ARG1 | P05089 | Arginase-1 | chr6 | GO:0009063 | Not Cancer Driver | No | 41 | 0.127 | 83 | 12 | 0.145 | 9 |
| ARG2 | ARG2 | P78540 | Arginase-2, mitochondrial | chr14 | GO:0009063 | Not Cancer Driver | No | 25 | 0.071 | 58 | 3 | 0.052 | 0 |
| ARHGAP11B | ARHGAP11B | Q3KRB8 | Inactive Rho GTPase-activating protein 11B | chr15 | GO:0009063 | Not Cancer Driver | No | 20 | 0.075 | 17 | 1 | 0.059 | 0 |
| ASPA | ASPA | P45381 | Aspartoacylase | chr17 | GO:0009063 | Not Cancer Driver | No | 58 | 0.185 | 3 | 0 | 0.0 | 42 |
| ASRGL1_ENST00000301776 | ASRGL1 | Q7L266 | Isoaspartyl peptidase/L-asparaginase | chr11 | GO:0009063 | Not Cancer Driver | No | 43 | 0.14 | 74 | 12 | 0.162 | 0 |
| AUH | AUH | Q13825 | Methylglutaconyl-CoA hydratase, mitochondrial | chr9 | GO:0009063 | Not Cancer Driver | No | 34 | 0.1 | 29 | 0 | 0.0 | 1 |
| BCAT2 | BCAT2 | O15382 | Branched-chain-amino-acid aminotransferase, mitochondrial | chr19 | GO:0009063 | Not Cancer Driver | No | 54 | 0.138 | 19 | 0 | 0.0 | 2 |
| BCKDHA | BCKDHA | P12694 | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | chr19 | GO:0009063 | Not Cancer Driver | No | 53 | 0.119 | 121 | 18 | 0.149 | 11 |
| BCKDHB | BCKDHB | P21953 | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | chr6 | GO:0009063 | Not Cancer Driver | No | 47 | 0.12 | 23 | 3 | 0.13 | 5 |
| BCKDK | BCKDK | O14874 | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | chr16 | GO:0009063 | Not Cancer Driver | No | 62 | 0.15 | 39 | 3 | 0.077 | 3 |
| BLMH | BLMH | Q13867 | Bleomycin hydrolase | chr17 | GO:0009063 | Not Cancer Driver | No | 54 | 0.119 | 15 | 1 | 0.067 | 0 |
| CARNMT1 | CARNMT1 | Q8N4J0 | Carnosine N-methyltransferase | chr9 | GO:0009063 | Not Cancer Driver | No | 42 | 0.103 | 75 | 1 | 0.013 | 0 |
| CARNS1_ENST00000307823 | CARNS1 | A5YM72 | Carnosine synthase 1 | chr11 | GO:0009063 | Not Cancer Driver | No | 74 | 0.089 | 42 | 4 | 0.095 | 0 |
| CBS_ENST00000359624 | CBS | P35520 | Cystathionine beta-synthase | chr21 | GO:0009063 | Not Cancer Driver | No | 61 | 0.111 | 160 | 19 | 0.119 | 103 |
| CDO1 | CDO1 | Q16878 | Cysteine dioxygenase type 1 | chr5 | GO:0009063 | Not Cancer Driver | No | 37 | 0.185 | 43 | 4 | 0.093 | 0 |
| CRYM | CRYM | Q14894 | Ketimine reductase mu-crystallin | chr16 | GO:0009063 | Not Cancer Driver | No | 34 | 0.108 | 10 | 0 | 0.0 | 1 |
| CSAD_ENST00000453446 | CSAD | Q9Y600 | Cysteine sulfinic acid decarboxylase | chr12 | GO:0009063 | Not Cancer Driver | No | 73 | 0.148 | 23 | 8 | 0.348 | 0 |
| DAO | DAO | P14920 | D-amino-acid oxidase | chr12 | GO:0009063 | Not Cancer Driver | No | 103 | 0.297 | 28 | 13 | 0.464 | 0 |
| DBT | DBT | P11182 | Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial | chr1 | GO:0009063 | Not Cancer Driver | No | 64 | 0.133 | 81 | 11 | 0.136 | 3 |
| DLD | DLD | P09622 | Dihydrolipoyl dehydrogenase, mitochondrial | chr7 | GO:0009063 | Not Cancer Driver | No | 67 | 0.132 | 17 | 0 | 0.0 | 10 |
| DLST | DLST | P36957 | Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial | chr14 | GO:0009063 | Not Cancer Driver | No | 53 | 0.117 | 190 | 32 | 0.168 | 1 |
| ECHS1 | ECHS1 | P30084 | Enoyl-CoA hydratase, mitochondrial | chr10 | GO:0009063 | Not Cancer Driver | No | 51 | 0.176 | 7 | 1 | 0.143 | 14 |
| ENOSF1_ENST00000251101 | ENOSF1 | Q7L5Y1 | Mitochondrial enolase superfamily member 1 | chr18 | GO:0009063 | Not Cancer Driver | No | 62 | 0.14 | 25 | 2 | 0.08 | 0 |
| ETFA | ETFA | P13804 | Electron transfer flavoprotein subunit alpha, mitochondrial | chr15 | GO:0009063 | Not Cancer Driver | No | 30 | 0.09 | 34 | 2 | 0.059 | 3 |
| ETFB_ENST00000309244 | ETFB | P38117 | Electron transfer flavoprotein subunit beta | chr19 | GO:0009063 | Not Cancer Driver | No | 37 | 0.145 | 38 | 4 | 0.105 | 2 |
| FAH_ENST00000561421 | FAH | P16930 | Fumarylacetoacetase | chr15 | GO:0009063 | Not Cancer Driver | No | 50 | 0.119 | 41 | 10 | 0.244 | 20 |
| FTCD_ENST00000291670 | FTCD | O95954 | Formimidoyltransferase-cyclodeaminase | chr21 | GO:0009063 | Not Cancer Driver | No | 86 | 0.159 | 44 | 36 | 0.818 | 2 |
| GAD1 | GAD1 | Q99259 | Glutamate decarboxylase 1 | chr2 | GO:0009063 | Not Cancer Driver | No | 113 | 0.19 | 55 | 5 | 0.091 | 1 |
| GAD2_ENST00000259271 | GAD2 | Q05329 | Glutamate decarboxylase 2 | chr10 | GO:0009063 | Not Cancer Driver | No | 148 | 0.253 | 37 | 7 | 0.189 | 0 |
| GCAT_ENST00000248924 | GCAT | O75600 | 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial | chr22 | GO:0009063 | Not Cancer Driver | No | 59 | 0.141 | 2 | 0 | 0.0 | 0 |
| GCSH | GCSH | P23434 | Glycine cleavage system H protein, mitochondrial | chr16 | GO:0009063 | Not Cancer Driver | No | 15 | 0.087 | 25 | 0 | 0.0 | 0 |
| GLDC | GLDC | P23378 | Glycine dehydrogenase (decarboxylating), mitochondrial | chr9 | GO:0009063 | Not Cancer Driver | No | 152 | 0.149 | 112 | 7 | 0.062 | 22 |
| GLS | GLS | O94925 | Glutaminase kidney isoform, mitochondrial | chr2 | GO:0009063 | Not Cancer Driver | No | 71 | 0.106 | 187 | 9 | 0.048 | 3 |
| GLS2 | GLS2 | Q9UI32 | Glutaminase liver isoform, mitochondrial | chr12 | GO:0009063 | Not Cancer Driver | No | 57 | 0.095 | 108 | 9 | 0.083 | 0 |
| GLUD1 | GLUD1 | P00367 | Glutamate dehydrogenase 1, mitochondrial | chr10 | GO:0009063 | Not Cancer Driver | No | 50 | 0.09 | 107 | 14 | 0.131 | 13 |
| GLUD2 | GLUD2 | P49448 | Glutamate dehydrogenase 2, mitochondrial | chrX | GO:0009063 | Not Cancer Driver | No | 145 | 0.26 | 117 | 37 | 0.316 | 0 |
| GLUL_ENST00000331872 | GLUL | P15104 | Glutamine synthetase | chr1 | GO:0009063 | Not Cancer Driver | No | 66 | 0.177 | 104 | 21 | 0.202 | 2 |
| GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | GO:0009063 | Not Cancer Driver | No | 56 | 0.136 | 35 | 5 | 0.143 | 0 |
| GOT2 | GOT2 | P00505 | Aspartate aminotransferase, mitochondrial | chr16 | GO:0009063 | Not Cancer Driver | No | 61 | 0.142 | 25 | 3 | 0.12 | 1 |
| GPT2 | GPT2 | Q8TD30 | Alanine aminotransferase 2 | chr16 | GO:0009063 | Not Cancer Driver | No | 61 | 0.117 | 68 | 5 | 0.074 | 1 |
| GPT_ENST00000528431 | GPT | P24298 | Alanine aminotransferase 1 | chr8 | GO:0009063 | Not Cancer Driver | No | 52 | 0.105 | 51 | 9 | 0.176 | 0 |
| GSTZ1 | GSTZ1 | O43708 | Maleylacetoacetate isomerase | chr14 | GO:0009063 | Not Cancer Driver | No | 30 | 0.139 | 19 | 2 | 0.105 | 2 |
| HAAO | HAAO | P46952 | 3-hydroxyanthranilate 3,4-dioxygenase | chr2 | GO:0009063 | Not Cancer Driver | No | 40 | 0.14 | 30 | 2 | 0.067 | 0 |
| HAL | HAL | P42357 | Histidine ammonia-lyase | chr12 | GO:0009063 | Not Cancer Driver | No | 98 | 0.149 | 34 | 6 | 0.176 | 4 |
| HDC | HDC | P19113 | Histidine decarboxylase | chr15 | GO:0009063 | Not Cancer Driver | No | 163 | 0.246 | 96 | 24 | 0.25 | 0 |
| HGD | HGD | Q93099 | Homogentisate 1,2-dioxygenase | chr3 | GO:0009063 | Not Cancer Driver | No | 75 | 0.169 | 78 | 23 | 0.295 | 68 |
| HIBADH | HIBADH | P31937 | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | chr7 | GO:0009063 | Not Cancer Driver | No | 28 | 0.083 | 7 | 2 | 0.286 | 0 |
| HIBCH | HIBCH | Q6NVY1 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | chr2 | GO:0009063 | Not Cancer Driver | No | 42 | 0.109 | 26 | 0 | 0.0 | 1 |
| HMGCL | HMGCL | P35914 | Hydroxymethylglutaryl-CoA lyase, mitochondrial | chr1 | GO:0009063 | Not Cancer Driver | No | 17 | 0.052 | 8 | 2 | 0.25 | 19 |
| HMGCLL1 | HMGCLL1 | Q8TB92 | 3-hydroxy-3-methylglutaryl-CoA lyase, cytoplasmic | chr6 | GO:0009063 | Not Cancer Driver | No | 113 | 0.305 | 2 | 1 | 0.5 | 0 |
| HNMT | HNMT | P50135 | Histamine N-methyltransferase | chr2 | GO:0009063 | Not Cancer Driver | No | 40 | 0.137 | 7 | 0 | 0.0 | 2 |
| HOGA1 | HOGA1 | Q86XE5 | 4-hydroxy-2-oxoglutarate aldolase, mitochondrial | chr10 | GO:0009063 | Not Cancer Driver | No | 34 | 0.104 | 2 | 0 | 0.0 | 2 |
| HPD | HPD | P32754 | 4-hydroxyphenylpyruvate dioxygenase | chr12 | GO:0009063 | Not Cancer Driver | No | 61 | 0.155 | 40 | 9 | 0.225 | 3 |
| HSD17B10 | HSD17B10 | Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | chrX | GO:0009063 | Not Cancer Driver | No | 27 | 0.103 | 15 | 3 | 0.2 | 11 |
| HYKK_ENST00000388988 | HYKK | A2RU49 | Hydroxylysine kinase | chr15 | GO:0009063 | Not Cancer Driver | No | 38 | 0.102 | 30 | 3 | 0.1 | 0 |
| IDO1_ENST00000522495 | IDO1 | P14902 | Indoleamine 2,3-dioxygenase 1 | chr8 | GO:0009063 | Not Cancer Driver | No | 82 | 0.203 | 41 | 8 | 0.195 | 0 |
| IDO2 | IDO2 | Q6ZQW0 | Indoleamine 2,3-dioxygenase 2 | chr8 | GO:0009063 | Not Cancer Driver | No | 93 | 0.221 | 35 | 5 | 0.143 | 0 |
| IL4I1_ENST00000391826 | IL4I1 | Q96RQ9 | L-amino-acid oxidase | chr19 | GO:0009063 | Not Cancer Driver | No | 65 | 0.115 | 136 | 14 | 0.103 | 0 |
| IVD | IVD | P26440 | Isovaleryl-CoA dehydrogenase, mitochondrial | chr15 | GO:0009063 | Not Cancer Driver | No | 46 | 0.108 | 8 | 0 | 0.0 | 14 |
| KMO | KMO | O15229 | Kynurenine 3-monooxygenase | chr1 | GO:0009063 | Not Cancer Driver | No | 77 | 0.158 | 0 | 0 | 0.0 | 0 |
| KYAT1_ENST00000302586 | KYAT1 | Q16773 | Kynurenine--oxoglutarate transaminase 1 | chr9 | GO:0009063 | Not Cancer Driver | No | 56 | 0.133 | 5 | 1 | 0.2 | 0 |
| KYAT3 | KYAT3 | Q6YP21 | Kynurenine--oxoglutarate transaminase 3 | chr1 | GO:0009063 | Not Cancer Driver | No | 67 | 0.148 | 0 | 0 | 0.0 | 0 |
| KYNU_ENST00000409512 | KYNU | Q16719 | Kynureninase | chr2 | GO:0009063 | Not Cancer Driver | No | 103 | 0.222 | 20 | 5 | 0.25 | 1 |
| MAT1A | MAT1A | Q00266 | S-adenosylmethionine synthase isoform type-1 | chr10 | GO:0009063 | Not Cancer Driver | No | 74 | 0.187 | 15 | 0 | 0.0 | 12 |
| MCCC1 | MCCC1 | Q96RQ3 | Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial | chr3 | GO:0009063 | Not Cancer Driver | No | 94 | 0.13 | 162 | 17 | 0.105 | 33 |
| MCCC2 | MCCC2 | Q9HCC0 | Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial | chr5 | GO:0009063 | Not Cancer Driver | No | 60 | 0.107 | 25 | 2 | 0.08 | 52 |
| MTRR_ENST00000440940 | MTRR | Q9UBK8 | Methionine synthase reductase | chr5 | GO:0009063 | Not Cancer Driver | No | 101 | 0.145 | 84 | 13 | 0.155 | 5 |
| OAT | OAT | P04181 | Ornithine aminotransferase, mitochondrial | chr10 | GO:0009063 | Not Cancer Driver | No | 52 | 0.118 | 17 | 0 | 0.0 | 27 |
| OTC | OTC | P00480 | Ornithine transcarbamylase, mitochondrial | chrX | GO:0009063 | Not Cancer Driver | No | 89 | 0.251 | 24 | 4 | 0.167 | 111 |
| PAH | PAH | P00439 | Phenylalanine-4-hydroxylase | chr12 | GO:0009063 | Not Cancer Driver | No | 133 | 0.294 | 13 | 4 | 0.308 | 222 |
| PIPOX | PIPOX | Q9P0Z9 | Peroxisomal sarcosine oxidase | chr17 | GO:0009063 | Not Cancer Driver | No | 52 | 0.133 | 21 | 3 | 0.143 | 0 |
| PRODH2 | PRODH2 | Q9UF12 | Hydroxyproline dehydrogenase | chr19 | GO:0009063 | Not Cancer Driver | No | 96 | 0.179 | 51 | 7 | 0.137 | 0 |
| PRODH_ENST00000610940 | PRODH | O43272 | Proline dehydrogenase 1, mitochondrial | chr22 | GO:0009063 | Not Cancer Driver | No | 62 | 0.103 | 67 | 8 | 0.119 | 16 |
| QDPR | QDPR | P09417 | Dihydropteridine reductase | chr4 | GO:0009063 | Not Cancer Driver | No | 41 | 0.168 | 25 | 3 | 0.12 | 16 |
| RIDA | RIDA | P52758 | 2-iminobutanoate/2-iminopropanoate deaminase | chr8 | GO:0009063 | Not Cancer Driver | No | 20 | 0.146 | 3 | 0 | 0.0 | 0 |
| SARDH_ENST00000439388 | SARDH | Q9UL12 | Sarcosine dehydrogenase, mitochondrial | chr9 | GO:0009063 | Not Cancer Driver | No | 144 | 0.157 | 132 | 24 | 0.182 | 2 |
| SDS | SDS | P20132 | L-serine dehydratase/L-threonine deaminase | chr12 | GO:0009063 | Not Cancer Driver | No | 40 | 0.122 | 17 | 1 | 0.059 | 0 |
| SDSL | SDSL | Q96GA7 | Serine dehydratase-like | chr12 | GO:0009063 | Not Cancer Driver | No | 48 | 0.146 | 15 | 1 | 0.067 | 0 |
| SHMT1 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | GO:0009063 | Not Cancer Driver | No | 51 | 0.106 | 32 | 7 | 0.219 | 0 |
| SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | GO:0009063 | Not Cancer Driver | No | 57 | 0.113 | 58 | 5 | 0.086 | 1 |
| SLC25A21 | SLC25A21 | Q9BQT8 | Mitochondrial 2-oxodicarboxylate carrier | chr14 | GO:0009063 | Not Cancer Driver | No | 44 | 0.147 | 0 | 0 | 0.0 | 1 |
| SLC25A44_ENST00000359511 | SLC25A44 | Q96H78 | Solute carrier family 25 member 44 | chr1 | GO:0009063 | Not Cancer Driver | No | 38 | 0.121 | 6 | 3 | 0.5 | 0 |
| TAT | TAT | P17735 | Tyrosine aminotransferase | chr16 | GO:0009063 | Not Cancer Driver | No | 102 | 0.225 | 75 | 21 | 0.28 | 1 |
| TDO2 | TDO2 | P48775 | Tryptophan 2,3-dioxygenase | chr4 | GO:0009063 | Not Cancer Driver | No | 64 | 0.158 | 31 | 9 | 0.29 | 1 |
| UROC1_ENST00000290868 | UROC1 | Q96N76 | Urocanate hydratase | chr3 | GO:0009063 | Not Cancer Driver | No | 151 | 0.223 | 37 | 9 | 0.243 | 2 |