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Total number of protein in "GO:0008654" GO term:  130

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABCA8 ABCA8 O94911 ABC-type organic anion transporter ABCA8 chr17 GO:0008654 Not Cancer Driver No 290 0.179 91 20 0.22 0
ABHD3 ABHD3 Q8WU67 Phospholipase ABHD3 chr18 GO:0008654 Not Cancer Driver No 43 0.105 0 0 0.0 0
ABHD4 ABHD4 Q8TB40 (Lyso)-N-acylphosphatidylethanolamine lipase chr14 GO:0008654 Not Cancer Driver No 46 0.135 39 5 0.128 0
ABHD5 ABHD5 Q8WTS1 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 chr3 GO:0008654 Not Cancer Driver No 34 0.097 18 1 0.056 4
ABHD8 ABHD8 Q96I13 Protein ABHD8 chr19 GO:0008654 Not Cancer Driver No 58 0.132 134 19 0.142 0
ACP6 ACP6 Q9NPH0 Lysophosphatidic acid phosphatase type 6 chr1 GO:0008654 Not Cancer Driver No 53 0.124 40 5 0.125 0
AGPAT1 AGPAT1 Q99943 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha chr6 GO:0008654 Not Cancer Driver No 36 0.127 38 5 0.132 0
AGPAT2_ENST00000538402 AGPAT2 O15120 1-acyl-sn-glycerol-3-phosphate acyltransferase beta chr9 GO:0008654 Not Cancer Driver No 25 0.09 23 2 0.087 3
AGPAT3_ENST00000398058 AGPAT3 Q9NRZ7 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma chr21 GO:0008654 Not Cancer Driver No 47 0.125 5 1 0.2 0
AGPAT4 AGPAT4 Q9NRZ5 1-acyl-sn-glycerol-3-phosphate acyltransferase delta chr6 GO:0008654 Not Cancer Driver No 60 0.159 9 1 0.111 0
AGPAT5 AGPAT5 Q9NUQ2 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon chr8 GO:0008654 Not Cancer Driver No 33 0.091 39 5 0.128 0
ALOX15_ENST00000293761 ALOX15 P16050 Polyunsaturated fatty acid lipoxygenase ALOX15 chr17 GO:0008654 Not Cancer Driver No 84 0.127 46 7 0.152 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0008654 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOA2 APOA2 P02652 Apolipoprotein A-II chr1 GO:0008654 Not Cancer Driver No 13 0.13 0 0 0.0 0
ATG14 ATG14 Q6ZNE5 Beclin 1-associated autophagy-related key regulator chr14 GO:0008654 Not Cancer Driver No 48 0.098 209 24 0.115 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0008654 Census, Compendium Yes 469 0.153 225 39 0.173 41
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0008654 Not Cancer Driver No 45 0.1 190 19 0.1 0
CDS1 CDS1 Q92903 Phosphatidate cytidylyltransferase 1 chr4 GO:0008654 Not Cancer Driver No 73 0.158 66 9 0.136 0
CDS2 CDS2 O95674 Phosphatidate cytidylyltransferase 2 chr20 GO:0008654 Not Cancer Driver No 48 0.108 49 4 0.082 0
CEPT1_ENST00000357172 CEPT1 Q9Y6K0 Choline/ethanolaminephosphotransferase 1 chr1 GO:0008654 Not Cancer Driver No 42 0.101 24 5 0.208 0
CHAT CHAT P28329 Choline O-acetyltransferase chr10 GO:0008654 Not Cancer Driver No 155 0.207 193 24 0.124 10
CHKA CHKA P35790 Choline kinase alpha chr11 GO:0008654 Not Cancer Driver No 45 0.098 119 4 0.034 0
CHKB CHKB Q9Y259 Choline/ethanolamine kinase chr22 GO:0008654 Not Cancer Driver No 42 0.106 37 3 0.081 2
CHPT1 CHPT1 Q8WUD6 Cholinephosphotransferase 1 chr12 GO:0008654 Not Cancer Driver No 30 0.074 1 0 0.0 0
DGKA DGKA P23743 Diacylglycerol kinase alpha chr12 GO:0008654 Not Cancer Driver No 87 0.118 76 14 0.184 0
DGKB DGKB Q9Y6T7 Diacylglycerol kinase beta chr7 GO:0008654 Not Cancer Driver No 227 0.282 163 66 0.405 0
DGKD DGKD Q16760 Diacylglycerol kinase delta chr2 GO:0008654 Not Cancer Driver No 160 0.132 441 60 0.136 0
DGKE DGKE P52429 Diacylglycerol kinase epsilon chr17 GO:0008654 Not Cancer Driver No 84 0.148 34 3 0.088 2
DGKG DGKG P49619 Diacylglycerol kinase gamma chr3 GO:0008654 Not Cancer Driver No 160 0.202 182 43 0.236 0
DGKH DGKH Q86XP1 Diacylglycerol kinase eta chr13 GO:0008654 Not Cancer Driver No 138 0.113 326 43 0.132 0
DGKQ DGKQ P52824 Diacylglycerol kinase theta chr4 GO:0008654 Not Cancer Driver No 56 0.059 264 11 0.042 0
DGKZ_ENST00000456247 DGKZ Q13574 Diacylglycerol kinase zeta chr11 GO:0008654 Not Cancer Driver No 87 0.094 410 42 0.102 0
DHDDS_ENST00000236342 DHDDS Q86SQ9 Dehydrodolichyl diphosphate synthase complex subunit DHDDS chr1 GO:0008654 Not Cancer Driver No 38 0.114 19 1 0.053 1
DHRS7B DHRS7B Q6IAN0 Dehydrogenase/reductase SDR family member 7B chr17 GO:0008654 Not Cancer Driver No 37 0.114 17 0 0.0 0
DOLK DOLK Q9UPQ8 Dolichol kinase chr9 GO:0008654 Not Cancer Driver No 49 0.091 12 1 0.083 2
DOLPP1 DOLPP1 Q86YN1 Dolichyldiphosphatase 1 chr9 GO:0008654 Not Cancer Driver No 21 0.088 2 0 0.0 0
ETNK1 ETNK1 Q9HBU6 Ethanolamine kinase 1 chr12 GO:0008654 Census Yes 49 0.108 81 5 0.062 0
ETNK2_ENST00000367202 ETNK2 Q9NVF9 Ethanolamine kinase 2 chr1 GO:0008654 Not Cancer Driver No 46 0.119 38 34 0.895 0
FABP5 FABP5 Q01469 Fatty acid-binding protein 5 chr8 GO:0008654 Not Cancer Driver No 15 0.111 4 4 1.0 0
FDPS_ENST00000368356 FDPS P14324 Farnesyl pyrophosphate synthase chr1 GO:0008654 Not Cancer Driver No 66 0.158 0 0 0.0 1
FIG4 FIG4 Q92562 Polyphosphoinositide phosphatase chr6 GO:0008654 Not Cancer Driver No 114 0.126 177 26 0.147 7
FITM1 FITM1 A5D6W6 Fat storage-inducing transmembrane protein 1 chr14 GO:0008654 Not Cancer Driver No 45 0.154 6 2 0.333 0
FITM2 FITM2 Q8N6M3 Acyl-coenzyme A diphosphatase FITM2 chr20 GO:0008654 Not Cancer Driver No 28 0.107 0 0 0.0 1
GGPS1 GGPS1 O95749 Geranylgeranyl pyrophosphate synthase chr1 GO:0008654 Not Cancer Driver No 27 0.09 12 0 0.0 0
GNPAT GNPAT O15228 Dihydroxyacetone phosphate acyltransferase chr1 GO:0008654 Not Cancer Driver No 86 0.126 6 3 0.5 3
GPAM GPAM Q9HCL2 Glycerol-3-phosphate acyltransferase 1, mitochondrial chr10 GO:0008654 Not Cancer Driver No 108 0.13 83 7 0.084 0
GPAT2_ENST00000359548 GPAT2 Q6NUI2 Glycerol-3-phosphate acyltransferase 2, mitochondrial chr2 GO:0008654 Not Cancer Driver No 75 0.094 34 6 0.176 0
GPAT3_ENST00000395226 GPAT3 Q53EU6 Glycerol-3-phosphate acyltransferase 3 chr4 GO:0008654 Not Cancer Driver No 56 0.129 3 0 0.0 0
GPAT4 GPAT4 Q86UL3 Glycerol-3-phosphate acyltransferase 4 chr8 GO:0008654 Not Cancer Driver No 64 0.14 3 0 0.0 0
HEXB HEXB P07686 Beta-hexosaminidase subunit beta chr5 GO:0008654 Not Cancer Driver No 45 0.081 0 0 0.0 9
HMGCS1_ENST00000433297 HMGCS1 Q01581 Hydroxymethylglutaryl-CoA synthase, cytoplasmic chr5 GO:0008654 Not Cancer Driver No 64 0.123 74 10 0.135 0
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0008654 Not Cancer Driver No 92 0.181 29 4 0.138 19
IDI1_ENST00000429642 IDI1 Q13907 Isopentenyl-diphosphate Delta-isomerase 1 chr10 GO:0008654 Not Cancer Driver No 20 0.088 26 3 0.115 0
IDI2 IDI2 Q9BXS1 Isopentenyl-diphosphate delta-isomerase 2 chr10 GO:0008654 Not Cancer Driver No 36 0.159 10 0 0.0 0
INPP4A INPP4A Q96PE3 Inositol polyphosphate-4-phosphatase type I A chr2 GO:0008654 Not Cancer Driver No 114 0.117 153 20 0.131 0
INPP4B_ENST00000513000 INPP4B O15327 Inositol polyphosphate 4-phosphatase type II chr4 GO:0008654 Not Cancer Driver No 145 0.157 191 36 0.188 0
ISYNA1 ISYNA1 Q9NPH2 Inositol-3-phosphate synthase 1 chr19 GO:0008654 Not Cancer Driver No 40 0.072 83 2 0.024 0
LCAT LCAT P04180 Phosphatidylcholine-sterol acyltransferase chr16 GO:0008654 Not Cancer Driver No 43 0.098 28 2 0.071 34
LCLAT1 LCLAT1 Q6UWP7 Lysocardiolipin acyltransferase 1 chr2 GO:0008654 Not Cancer Driver No 59 0.143 9 3 0.333 0
LIPH LIPH Q8WWY8 Lipase member H chr3 GO:0008654 Not Cancer Driver No 71 0.157 32 8 0.25 2
LIPI_ENST00000536861 LIPI Q6XZB0 Lipase member I chr21 GO:0008654 Not Cancer Driver No 142 0.309 5 0 0.0 1
LPCAT1 LPCAT1 Q8NF37 Lysophosphatidylcholine acyltransferase 1 chr5 GO:0008654 Not Cancer Driver No 85 0.159 66 11 0.167 0
LPCAT2 LPCAT2 Q7L5N7 Lysophosphatidylcholine acyltransferase 2 chr16 GO:0008654 Not Cancer Driver No 78 0.143 35 5 0.143 0
LPCAT3 LPCAT3 Q6P1A2 Lysophospholipid acyltransferase 5 chr12 GO:0008654 Not Cancer Driver No 54 0.111 1 0 0.0 0
LPCAT4 LPCAT4 Q643R3 Lysophospholipid acyltransferase LPCAT4 chr15 GO:0008654 Not Cancer Driver No 52 0.099 92 10 0.109 0
LPGAT1 LPGAT1 Q92604 Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 chr1 GO:0008654 Not Cancer Driver No 38 0.103 11 0 0.0 0
LPIN1_ENST00000256720 LPIN1 Q14693 Phosphatidate phosphatase LPIN1 chr2 GO:0008654 Not Cancer Driver No 120 0.135 447 70 0.157 0
MBOAT1 MBOAT1 Q6ZNC8 Lysophospholipid acyltransferase 1 chr6 GO:0008654 Not Cancer Driver No 59 0.119 15 5 0.333 0
MBOAT2 MBOAT2 Q6ZWT7 Lysophospholipid acyltransferase 2 chr2 GO:0008654 Not Cancer Driver No 59 0.113 36 6 0.167 0
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0008654 Not Cancer Driver No 61 0.112 36 4 0.111 7
MVD MVD P53602 Diphosphomevalonate decarboxylase chr16 GO:0008654 Not Cancer Driver No 47 0.117 49 10 0.204 3
MVK MVK Q03426 Mevalonate kinase chr12 GO:0008654 Not Cancer Driver No 50 0.126 25 0 0.0 38
NUS1 NUS1 Q96E22 Dehydrodolichyl diphosphate synthase complex subunit NUS1 chr6 GO:0008654 Not Cancer Driver No 21 0.072 13 0 0.0 1
OCRL OCRL Q01968 Inositol polyphosphate 5-phosphatase OCRL chrX GO:0008654 Not Cancer Driver No 151 0.168 126 24 0.19 41
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0008654 Not Cancer Driver No 22 0.144 9 1 0.111 0
OSBP OSBP P22059 Oxysterol-binding protein 1 chr11 GO:0008654 Not Cancer Driver No 83 0.103 386 39 0.101 0
PCYT1A_ENST00000431016 PCYT1A P49585 Choline-phosphate cytidylyltransferase A chr3 GO:0008654 Not Cancer Driver No 52 0.142 145 25 0.172 6
PCYT1B PCYT1B Q9Y5K3 Choline-phosphate cytidylyltransferase B chrX GO:0008654 Not Cancer Driver No 60 0.163 171 17 0.099 0
PCYT2_ENST00000538936 PCYT2 Q99447 Ethanolamine-phosphate cytidylyltransferase chr17 GO:0008654 Not Cancer Driver No 45 0.116 101 12 0.119 0
PEMT_ENST00000395783 PEMT Q9UBM1 Phosphatidylethanolamine N-methyltransferase chr17 GO:0008654 Not Cancer Driver No 21 0.106 1 0 0.0 0
PIK3C2A PIK3C2A O00443 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha chr11 GO:0008654 Not Cancer Driver No 187 0.111 350 43 0.123 0
PIK3C2B PIK3C2B O00750 Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta chr1 GO:0008654 Not Cancer Driver No 241 0.147 425 71 0.167 0
PIK3C2G_ENST00000433979 PIK3C2G O75747 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma chr12 GO:0008654 Not Cancer Driver No 283 0.196 211 37 0.175 0
PIK3C3 PIK3C3 Q8NEB9 Phosphatidylinositol 3-kinase catalytic subunit type 3 chr18 GO:0008654 Not Cancer Driver No 127 0.143 191 34 0.178 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0008654 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CB_ENST00000477593 PIK3CB P42338 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform chr3 GO:0008654 Census, Compendium Yes 150 0.14 42 4 0.095 0
PIK3CD PIK3CD O00329 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform chr1 GO:0008654 Not Cancer Driver No 140 0.134 60 13 0.217 1
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0008654 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIK3R3_ENST00000372006 PIK3R3 Q92569 Phosphatidylinositol 3-kinase regulatory subunit gamma chr1 GO:0008654 Not Cancer Driver No 51 0.111 149 20 0.134 0
PIK3R4 PIK3R4 Q99570 Phosphoinositide 3-kinase regulatory subunit 4 chr3 GO:0008654 Not Cancer Driver No 193 0.142 315 45 0.143 0
PIKFYVE PIKFYVE Q9Y2I7 1-phosphatidylinositol 3-phosphate 5-kinase chr2 GO:0008654 Not Cancer Driver No 278 0.133 848 101 0.119 1
PIP4K2A PIP4K2A P48426 Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha chr10 GO:0008654 Not Cancer Driver No 56 0.138 123 15 0.122 0
PIP4K2C_ENST00000540759 PIP4K2C Q8TBX8 Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma chr12 GO:0008654 Not Cancer Driver No 62 0.147 111 23 0.207 0
PIP5K1A PIP5K1A Q99755 Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha chr1 GO:0008654 Not Cancer Driver No 74 0.132 216 29 0.134 0
PISD_ENST00000439502 PISD Q9UG56 Phosphatidylserine decarboxylase proenzyme, mitochondrial chr22 GO:0008654 Not Cancer Driver No 42 0.103 8 3 0.375 2
PLA2G16 PLAAT3 P53816 Phospholipase A and acyltransferase 3 chr11 GO:0008654 Not Cancer Driver No 16 0.099 13 1 0.077 0
PLA2G4A PLA2G4A P47712 Cytosolic phospholipase A2 chr1 GO:0008654 Not Cancer Driver No 149 0.199 129 28 0.217 1
PLA2G4C_ENST00000599921 PLA2G4C Q9UP65 Cytosolic phospholipase A2 gamma chr19 GO:0008654 Not Cancer Driver No 107 0.198 62 9 0.145 0
PLD1 PLD1 Q13393 Phospholipase D1 chr3 GO:0008654 Not Cancer Driver No 181 0.169 133 32 0.241 1
PLD2 PLD2 O14939 Phospholipase D2 chr17 GO:0008654 Not Cancer Driver No 107 0.115 97 8 0.082 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0008654 Not Cancer Driver No 43 0.135 92 13 0.141 0
PMVK PMVK Q15126 Phosphomevalonate kinase chr1 GO:0008654 Not Cancer Driver No 38 0.198 3 0 0.0 0
PNPLA3 PNPLA3 Q9NST1 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 chr22 GO:0008654 Not Cancer Driver No 54 0.112 33 7 0.212 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0008654 Not Cancer Driver No 72 0.163 69 7 0.101 0
PTDSS1 PTDSS1 P48651 Phosphatidylserine synthase 1 chr8 GO:0008654 Not Cancer Driver No 81 0.171 44 7 0.159 3
PTDSS2 PTDSS2 Q9BVG9 Phosphatidylserine synthase 2 chr11 GO:0008654 Not Cancer Driver No 41 0.084 92 4 0.043 0
SAMD8 SAMD8 Q96LT4 Sphingomyelin synthase-related protein 1 chr10 GO:0008654 Not Cancer Driver No 40 0.096 0 0 0.0 0
SELENOI_ENST00000613142 SELENOI Q9C0D9 Ethanolaminephosphotransferase 1 chr2 GO:0008654 Not Cancer Driver No 41 0.103 0 0 0.0 1
SERAC1 SERAC1 Q96JX3 Protein SERAC1 chr6 GO:0008654 Not Cancer Driver No 70 0.107 41 3 0.073 3
SERINC1 SERINC1 Q9NRX5 Serine incorporator 1 chr6 GO:0008654 Not Cancer Driver No 51 0.113 21 1 0.048 0
SERINC4 SERINC4 A6NH21 Serine incorporator 4 chr15 GO:0008654 Not Cancer Driver No 28 0.054 23 3 0.13 0
SERINC5_ENST00000509193 SERINC5 Q86VE9 Serine incorporator 5 chr5 GO:0008654 Not Cancer Driver No 38 0.09 13 1 0.077 0
SGMS1 SGMS1 Q86VZ5 Phosphatidylcholine:ceramide cholinephosphotransferase 1 chr10 GO:0008654 Not Cancer Driver No 85 0.206 37 8 0.216 0
SGMS2 SGMS2 Q8NHU3 Phosphatidylcholine:ceramide cholinephosphotransferase 2 chr4 GO:0008654 Not Cancer Driver No 37 0.101 49 7 0.143 0
SLC27A1 SLC27A1 Q6PCB7 Long-chain fatty acid transport protein 1 chr19 GO:0008654 Not Cancer Driver No 88 0.136 16 0 0.0 0
SLC44A1 SLC44A1 Q8WWI5 Choline transporter-like protein 1 chr9 GO:0008654 Not Cancer Driver No 75 0.114 2 0 0.0 0
SLC44A2 SLC44A2 Q8IWA5 Choline transporter-like protein 2 chr19 GO:0008654 Not Cancer Driver No 94 0.133 6 0 0.0 0
SLC44A3 SLC44A3 Q8N4M1 Choline transporter-like protein 3 chr1 GO:0008654 Not Cancer Driver No 76 0.116 13 4 0.308 0
SLC44A4 SLC44A4 Q53GD3 Choline transporter-like protein 4 chr6 GO:0008654 Not Cancer Driver No 77 0.108 24 3 0.125 1
SLC44A5 SLC44A5 Q8NCS7 Choline transporter-like protein 5 chr1 GO:0008654 Not Cancer Driver No 208 0.289 32 17 0.531 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0008654 Not Cancer Driver No 82 0.125 293 39 0.133 0
SPTLC1 SPTLC1 O15269 Serine palmitoyltransferase 1 chr9 GO:0008654 Not Cancer Driver No 50 0.106 27 5 0.185 5
SPTLC2 SPTLC2 O15270 Serine palmitoyltransferase 2 chr14 GO:0008654 Not Cancer Driver No 72 0.128 9 2 0.222 5
SRD5A3 SRD5A3 Q9H8P0 Polyprenol reductase chr4 GO:0008654 Not Cancer Driver No 35 0.11 0 0 0.0 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0008654 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0008654 Not Cancer Driver No 189 0.126 545 70 0.128 0
TAMM41_ENST00000444133 TAMM41 Q96BW9 Phosphatidate cytidylyltransferase, mitochondrial chr3 GO:0008654 Not Cancer Driver No 21 0.046 21 0 0.0 0
TMEM38B TMEM38B Q9NVV0 Trimeric intracellular cation channel type B chr9 GO:0008654 Not Cancer Driver No 47 0.162 37 7 0.189 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0008654 Not Cancer Driver No 89 0.127 243 28 0.115 0
VAPA_ENST00000400000 VAPA Q9P0L0 Vesicle-associated membrane protein-associated protein A chr18 GO:0008654 Not Cancer Driver No 24 0.096 184 14 0.076 0