Total number of protein in "GO:0008652" GO term: 72
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AASDHPPT | AASDHPPT | Q9NRN7 | L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | chr11 | GO:0008652 | Not Cancer Driver | No | 52 | 0.168 | 27 | 2 | 0.074 | 0 |
| AASS | AASS | Q9UDR5 | Alpha-aminoadipic semialdehyde synthase, mitochondrial | chr7 | GO:0008652 | Not Cancer Driver | No | 161 | 0.174 | 18 | 3 | 0.167 | 0 |
| ABAT_ENST00000268251 | ABAT | P80404 | 4-aminobutyrate aminotransferase, mitochondrial | chr16 | GO:0008652 | Not Cancer Driver | No | 84 | 0.168 | 28 | 5 | 0.179 | 1 |
| AC068533.4 | AC068533.4 | H7C0S8 | Argininosuccinate lyase (Fragment) | chr7 | GO:0008652 | Not Cancer Driver | No | 42 | 0.137 | 66 | 3 | 0.045 | 0 |
| ADI1 | ADI1 | Q9BV57 | Acireductone dioxygenase | chr2 | GO:0008652 | Not Cancer Driver | No | 27 | 0.151 | 23 | 1 | 0.043 | 0 |
| AGXT | AGXT | P21549 | Alanine--glyoxylate aminotransferase | chr2 | GO:0008652 | Not Cancer Driver | No | 56 | 0.143 | 20 | 0 | 0.0 | 40 |
| AGXT2 | AGXT2 | Q9BYV1 | Alanine--glyoxylate aminotransferase 2, mitochondrial | chr5 | GO:0008652 | Not Cancer Driver | No | 136 | 0.265 | 11 | 5 | 0.455 | 0 |
| ALDH18A1 | ALDH18A1 | P54886 | Delta-1-pyrroline-5-carboxylate synthase | chr10 | GO:0008652 | Not Cancer Driver | No | 94 | 0.118 | 86 | 13 | 0.151 | 15 |
| ALDH1A1 | ALDH1A1 | P00352 | Aldehyde dehydrogenase 1A1 | chr9 | GO:0008652 | Not Cancer Driver | No | 65 | 0.13 | 29 | 3 | 0.103 | 0 |
| APIP | APIP | Q96GX9 | Methylthioribulose-1-phosphate dehydratase | chr11 | GO:0008652 | Not Cancer Driver | No | 24 | 0.099 | 26 | 1 | 0.038 | 0 |
| ASL_ENST00000395332 | ASL | P04424 | Argininosuccinate lyase | chr7 | GO:0008652 | Not Cancer Driver | No | 77 | 0.166 | 36 | 2 | 0.056 | 63 |
| ASNSD1 | ASNSD1 | Q9NWL6 | Asparagine synthetase domain-containing protein 1 | chr2 | GO:0008652 | Not Cancer Driver | No | 83 | 0.129 | 42 | 9 | 0.214 | 0 |
| ASNS_ENST00000394308 | ASNS | P08243 | Asparagine synthetase [glutamine-hydrolyzing] | chr7 | GO:0008652 | Not Cancer Driver | No | 81 | 0.144 | 11 | 0 | 0.0 | 3 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0008652 | Not Cancer Driver | No | 65 | 0.158 | 63 | 8 | 0.127 | 86 |
| BCAT1_ENST00000261192 | BCAT1 | P54687 | Branched-chain-amino-acid aminotransferase, cytosolic | chr12 | GO:0008652 | Not Cancer Driver | No | 67 | 0.174 | 8 | 2 | 0.25 | 0 |
| BCAT2 | BCAT2 | O15382 | Branched-chain-amino-acid aminotransferase, mitochondrial | chr19 | GO:0008652 | Not Cancer Driver | No | 54 | 0.138 | 19 | 0 | 0.0 | 2 |
| BHMT | BHMT | Q93088 | Betaine--homocysteine S-methyltransferase 1 | chr5 | GO:0008652 | Not Cancer Driver | No | 78 | 0.192 | 93 | 12 | 0.129 | 0 |
| BHMT2 | BHMT2 | Q9H2M3 | S-methylmethionine--homocysteine S-methyltransferase BHMT2 | chr5 | GO:0008652 | Not Cancer Driver | No | 54 | 0.149 | 30 | 4 | 0.133 | 0 |
| CAD | CAD | P27708 | CAD protein | chr2 | GO:0008652 | Not Cancer Driver | No | 287 | 0.129 | 368 | 52 | 0.141 | 1 |
| CBS_ENST00000359624 | CBS | P35520 | Cystathionine beta-synthase | chr21 | GO:0008652 | Not Cancer Driver | No | 61 | 0.111 | 160 | 19 | 0.119 | 103 |
| CPS1_ENST00000233072 | CPS1 | P31327 | Carbamoyl-phosphate synthase [ammonia], mitochondrial | chr2 | GO:0008652 | Not Cancer Driver | No | 368 | 0.245 | 73 | 22 | 0.301 | 140 |
| CTH | CTH | P32929 | Cystathionine gamma-lyase | chr1 | GO:0008652 | Not Cancer Driver | No | 45 | 0.111 | 49 | 6 | 0.122 | 2 |
| DHFR | DHFR | P00374 | Dihydrofolate reductase | chr5 | GO:0008652 | Not Cancer Driver | No | 16 | 0.086 | 12 | 2 | 0.167 | 2 |
| DHFR2_ENST00000314636 | DHFR2 | Q86XF0 | Dihydrofolate reductase 2, mitochondrial | chr3 | GO:0008652 | Not Cancer Driver | No | 25 | 0.134 | 20 | 0 | 0.0 | 0 |
| DPYD | DPYD | Q12882 | Dihydropyrimidine dehydrogenase [NADP(+)] | chr1 | GO:0008652 | Not Cancer Driver | No | 303 | 0.296 | 77 | 23 | 0.299 | 3 |
| ENOPH1 | ENOPH1 | Q9UHY7 | Enolase-phosphatase E1 | chr4 | GO:0008652 | Not Cancer Driver | No | 35 | 0.134 | 14 | 2 | 0.143 | 0 |
| GAD1 | GAD1 | Q99259 | Glutamate decarboxylase 1 | chr2 | GO:0008652 | Not Cancer Driver | No | 113 | 0.19 | 55 | 5 | 0.091 | 1 |
| GGT1_ENST00000248923 | GGT1 | P19440 | Glutathione hydrolase 1 proenzyme | chr22 | GO:0008652 | Not Cancer Driver | No | 83 | 0.146 | 88 | 14 | 0.159 | 0 |
| GLS | GLS | O94925 | Glutaminase kidney isoform, mitochondrial | chr2 | GO:0008652 | Not Cancer Driver | No | 71 | 0.106 | 187 | 9 | 0.048 | 3 |
| GLS2 | GLS2 | Q9UI32 | Glutaminase liver isoform, mitochondrial | chr12 | GO:0008652 | Not Cancer Driver | No | 57 | 0.095 | 108 | 9 | 0.083 | 0 |
| GLUD1 | GLUD1 | P00367 | Glutamate dehydrogenase 1, mitochondrial | chr10 | GO:0008652 | Not Cancer Driver | No | 50 | 0.09 | 107 | 14 | 0.131 | 13 |
| GLUD2 | GLUD2 | P49448 | Glutamate dehydrogenase 2, mitochondrial | chrX | GO:0008652 | Not Cancer Driver | No | 145 | 0.26 | 117 | 37 | 0.316 | 0 |
| GLUL_ENST00000331872 | GLUL | P15104 | Glutamine synthetase | chr1 | GO:0008652 | Not Cancer Driver | No | 66 | 0.177 | 104 | 21 | 0.202 | 2 |
| GOT1 | GOT1 | P17174 | Aspartate aminotransferase, cytoplasmic | chr10 | GO:0008652 | Not Cancer Driver | No | 56 | 0.136 | 35 | 5 | 0.143 | 0 |
| GOT1L1 | GOT1L1 | Q8NHS2 | Putative aspartate aminotransferase, cytoplasmic 2 | chr8 | GO:0008652 | Not Cancer Driver | No | 62 | 0.147 | 0 | 0 | 0.0 | 0 |
| GOT2 | GOT2 | P00505 | Aspartate aminotransferase, mitochondrial | chr16 | GO:0008652 | Not Cancer Driver | No | 61 | 0.142 | 25 | 3 | 0.12 | 1 |
| ILVBL | ILVBL | A1L0T0 | 2-hydroxyacyl-CoA lyase 2 | chr19 | GO:0008652 | Not Cancer Driver | No | 86 | 0.136 | 30 | 1 | 0.033 | 0 |
| LGSN | LGSN | Q5TDP6 | Lengsin | chr6 | GO:0008652 | Not Cancer Driver | No | 136 | 0.267 | 91 | 22 | 0.242 | 0 |
| MRI1 | MRI1 | Q9BV20 | Methylthioribose-1-phosphate isomerase | chr19 | GO:0008652 | Not Cancer Driver | No | 26 | 0.07 | 47 | 8 | 0.17 | 0 |
| MTAP | MTAP | Q13126 | S-methyl-5'-thioadenosine phosphorylase | chr9 | GO:0008652 | Not Cancer Driver | No | 37 | 0.131 | 15 | 0 | 0.0 | 0 |
| MTHFD1 | MTHFD1 | P11586 | C-1-tetrahydrofolate synthase, cytoplasmic | chr14 | GO:0008652 | Not Cancer Driver | No | 103 | 0.11 | 129 | 11 | 0.085 | 6 |
| MTHFD2L | MTHFD2L | Q9H903 | Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2, mitochondrial | chr4 | GO:0008652 | Not Cancer Driver | No | 45 | 0.13 | 59 | 6 | 0.102 | 0 |
| MTHFR_ENST00000376590 | MTHFR | P42898 | Methylenetetrahydrofolate reductase | chr1 | GO:0008652 | Not Cancer Driver | No | 95 | 0.145 | 125 | 22 | 0.176 | 53 |
| MTR | MTR | Q99707 | Methionine synthase | chr1 | GO:0008652 | Not Cancer Driver | No | 151 | 0.119 | 104 | 17 | 0.163 | 2 |
| MTRR_ENST00000440940 | MTRR | Q9UBK8 | Methionine synthase reductase | chr5 | GO:0008652 | Not Cancer Driver | No | 101 | 0.145 | 84 | 13 | 0.155 | 5 |
| NAGS | NAGS | Q8N159 | N-acetylglutamate synthase, mitochondrial | chr17 | GO:0008652 | Not Cancer Driver | No | 35 | 0.066 | 116 | 6 | 0.052 | 6 |
| NOXRED1 | NOXRED1 | Q6NXP6 | NADP-dependent oxidoreductase domain-containing protein 1 | chr14 | GO:0008652 | Not Cancer Driver | No | 50 | 0.139 | 4 | 1 | 0.25 | 0 |
| OAT | OAT | P04181 | Ornithine aminotransferase, mitochondrial | chr10 | GO:0008652 | Not Cancer Driver | No | 52 | 0.118 | 17 | 0 | 0.0 | 27 |
| OTC | OTC | P00480 | Ornithine transcarbamylase, mitochondrial | chrX | GO:0008652 | Not Cancer Driver | No | 89 | 0.251 | 24 | 4 | 0.167 | 111 |
| PAH | PAH | P00439 | Phenylalanine-4-hydroxylase | chr12 | GO:0008652 | Not Cancer Driver | No | 133 | 0.294 | 13 | 4 | 0.308 | 222 |
| PCBD1 | PCBD1 | P61457 | Pterin-4-alpha-carbinolamine dehydratase | chr10 | GO:0008652 | Not Cancer Driver | No | 8 | 0.077 | 7 | 0 | 0.0 | 3 |
| PCBD2_ENST00000254908 | PCBD2 | Q9H0N5 | Pterin-4-alpha-carbinolamine dehydratase 2 | chr5 | GO:0008652 | Not Cancer Driver | No | 6 | 0.046 | 3 | 0 | 0.0 | 0 |
| PHGDH_ENST00000641023 | PHGDH | O43175 | D-3-phosphoglycerate dehydrogenase | chr1 | GO:0008652 | Not Cancer Driver | No | 51 | 0.096 | 38 | 4 | 0.105 | 8 |
| PLOD2_ENST00000360060 | PLOD2 | O00469 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | chr3 | GO:0008652 | Not Cancer Driver | No | 109 | 0.148 | 17 | 3 | 0.176 | 4 |
| PLOD3 | PLOD3 | O60568 | Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 | chr7 | GO:0008652 | Not Cancer Driver | No | 108 | 0.146 | 65 | 8 | 0.123 | 1 |
| PSAT1 | PSAT1 | Q9Y617 | Phosphoserine aminotransferase | chr9 | GO:0008652 | Not Cancer Driver | No | 54 | 0.146 | 3 | 1 | 0.333 | 3 |
| PSPH_ENST00000275605 | PSPH | P78330 | Phosphoserine phosphatase | chr7 | GO:0008652 | Not Cancer Driver | No | 44 | 0.196 | 21 | 6 | 0.286 | 3 |
| PYCR1_ENST00000329875 | PYCR1 | P32322 | Pyrroline-5-carboxylate reductase 1, mitochondrial | chr17 | GO:0008652 | Not Cancer Driver | No | 31 | 0.097 | 67 | 10 | 0.149 | 9 |
| PYCR2 | PYCR2 | Q96C36 | Pyrroline-5-carboxylate reductase 2 | chr1 | GO:0008652 | Not Cancer Driver | No | 31 | 0.097 | 41 | 3 | 0.073 | 2 |
| PYCR3_ENST00000495276 | PYCR3 | Q53H96 | Pyrroline-5-carboxylate reductase 3 | chr8 | GO:0008652 | Not Cancer Driver | No | 21 | 0.077 | 11 | 0 | 0.0 | 0 |
| SDS | SDS | P20132 | L-serine dehydratase/L-threonine deaminase | chr12 | GO:0008652 | Not Cancer Driver | No | 40 | 0.122 | 17 | 1 | 0.059 | 0 |
| SDSL | SDSL | Q96GA7 | Serine dehydratase-like | chr12 | GO:0008652 | Not Cancer Driver | No | 48 | 0.146 | 15 | 1 | 0.067 | 0 |
| SEPHS1 | SEPHS1 | P49903 | Selenide, water dikinase 1 | chr10 | GO:0008652 | Not Cancer Driver | No | 58 | 0.148 | 29 | 10 | 0.345 | 0 |
| SEPHS2 | SEPHS2 | Q99611 | Selenide, water dikinase 2 | chr16 | GO:0008652 | Not Cancer Driver | No | 48 | 0.107 | 104 | 2 | 0.019 | 0 |
| SERINC3_ENST00000255175 | SERINC3 | Q13530 | Serine incorporator 3 | chr20 | GO:0008652 | Not Cancer Driver | No | 73 | 0.154 | 38 | 9 | 0.237 | 0 |
| SERINC5_ENST00000509193 | SERINC5 | Q86VE9 | Serine incorporator 5 | chr5 | GO:0008652 | Not Cancer Driver | No | 38 | 0.09 | 13 | 1 | 0.077 | 0 |
| SHMT1 | SHMT1 | P34896 | Serine hydroxymethyltransferase, cytosolic | chr17 | GO:0008652 | Not Cancer Driver | No | 51 | 0.106 | 32 | 7 | 0.219 | 0 |
| SHMT2 | SHMT2 | P34897 | Serine hydroxymethyltransferase, mitochondrial | chr12 | GO:0008652 | Not Cancer Driver | No | 57 | 0.113 | 58 | 5 | 0.086 | 1 |
| SLC1A3 | SLC1A3 | P43003 | Excitatory amino acid transporter 1 | chr5 | GO:0008652 | Not Cancer Driver | No | 100 | 0.185 | 55 | 9 | 0.164 | 1 |
| SLC25A12 | SLC25A12 | O75746 | Calcium-binding mitochondrial carrier protein Aralar1 | chr2 | GO:0008652 | Not Cancer Driver | No | 110 | 0.162 | 21 | 7 | 0.333 | 2 |
| SRR | SRR | Q9GZT4 | Serine racemase | chr17 | GO:0008652 | Not Cancer Driver | No | 40 | 0.118 | 32 | 6 | 0.188 | 0 |
| UPB1 | UPB1 | Q9UBR1 | Beta-ureidopropionase | chr22 | GO:0008652 | Not Cancer Driver | No | 66 | 0.172 | 22 | 7 | 0.318 | 8 |