Total number of protein in "GO:0008637" GO term: 53
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACAA2 | ACAA2 | P42765 | 3-ketoacyl-CoA thiolase, mitochondrial | chr18 | GO:0008637 | Not Cancer Driver | No | 42 | 0.106 | 51 | 2 | 0.039 | 0 |
| AIFM2_ENST00000307864 | AIFM2 | Q9BRQ8 | Ferroptosis suppressor protein 1 | chr10 | GO:0008637 | Not Cancer Driver | No | 47 | 0.126 | 8 | 0 | 0.0 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0008637 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0008637 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| ATG3 | ATG3 | Q9NT62 | Ubiquitin-like-conjugating enzyme ATG3 | chr3 | GO:0008637 | Not Cancer Driver | No | 29 | 0.092 | 110 | 9 | 0.082 | 0 |
| ATP2A1 | ATP2A1 | O14983 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | chr16 | GO:0008637 | Not Cancer Driver | No | 157 | 0.157 | 80 | 11 | 0.138 | 1 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0008637 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0008637 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0008637 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BBC3 | BBC3 | Q96PG8 | Bcl-2-binding component 3, isoforms 3/4 | chr19 | GO:0008637 | Not Cancer Driver | No | 20 | 0.077 | 253 | 20 | 0.079 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0008637 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0008637 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BCL2_ENST00000333681 | BCL2 | P10415 | Apoptosis regulator Bcl-2 | chr18 | GO:0008637 | Census, Compendium | Yes | 24 | 0.1 | 72 | 5 | 0.069 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0008637 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BIK | BIK | Q13323 | Bcl-2-interacting killer | chr22 | GO:0008637 | Not Cancer Driver | No | 16 | 0.1 | 21 | 4 | 0.19 | 0 |
| BLOC1S2 | BLOC1S2 | Q6QNY1 | Biogenesis of lysosome-related organelles complex 1 subunit 2 | chr10 | GO:0008637 | Not Cancer Driver | No | 17 | 0.12 | 34 | 6 | 0.176 | 0 |
| BNIP3L | BNIP3L | O60238 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like | chr8 | GO:0008637 | Not Cancer Driver | No | 16 | 0.073 | 175 | 14 | 0.08 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0008637 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CAMK2A_ENST00000348628 | CAMK2A | Q9UQM7 | Calcium/calmodulin-dependent protein kinase type II subunit alpha | chr5 | GO:0008637 | Not Cancer Driver | No | 83 | 0.174 | 62 | 10 | 0.161 | 7 |
| CCAR2 | CCAR2 | Q8N163 | Cell cycle and apoptosis regulator protein 2 | chr8 | GO:0008637 | Not Cancer Driver | No | 102 | 0.111 | 528 | 62 | 0.117 | 0 |
| CLU_ENST00000523500 | CLU | P10909 | Clusterin | chr8 | GO:0008637 | Not Cancer Driver | No | 69 | 0.154 | 156 | 27 | 0.173 | 0 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | GO:0008637 | Not Cancer Driver | No | 67 | 0.091 | 212 | 23 | 0.108 | 7 |
| ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0008637 | Census, Compendium | Yes | 428 | 0.327 | 323 | 116 | 0.359 | 2 |
| EYA2 | EYA2 | O00167 | Eyes absent homolog 2 | chr20 | GO:0008637 | Not Cancer Driver | No | 107 | 0.199 | 204 | 50 | 0.245 | 0 |
| FIS1 | FIS1 | Q9Y3D6 | Mitochondrial fission 1 protein | chr7 | GO:0008637 | Not Cancer Driver | No | 25 | 0.164 | 6 | 0 | 0.0 | 0 |
| FZD9 | FZD9 | O00144 | Frizzled-9 | chr7 | GO:0008637 | Not Cancer Driver | No | 55 | 0.093 | 61 | 0 | 0.0 | 0 |
| GCLM | GCLM | P48507 | Glutamate--cysteine ligase regulatory subunit | chr1 | GO:0008637 | Not Cancer Driver | No | 32 | 0.117 | 31 | 3 | 0.097 | 0 |
| GGCT | GGCT | O75223 | Gamma-glutamylcyclotransferase | chr7 | GO:0008637 | Not Cancer Driver | No | 25 | 0.133 | 51 | 2 | 0.039 | 0 |
| HK2 | HK2 | P52789 | Hexokinase-2 | chr2 | GO:0008637 | Not Cancer Driver | No | 138 | 0.15 | 77 | 7 | 0.091 | 0 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0008637 | Not Cancer Driver | No | 61 | 0.106 | 82 | 6 | 0.073 | 2 |
| IFI6_ENST00000361157 | IFI6 | P09912 | Interferon alpha-inducible protein 6 | chr1 | GO:0008637 | Not Cancer Driver | No | 12 | 0.092 | 7 | 0 | 0.0 | 0 |
| IFIT2_ENST00000371826 | IFIT2 | P09913 | Interferon-induced protein with tetratricopeptide repeats 2 | chr10 | GO:0008637 | Not Cancer Driver | No | 73 | 0.155 | 85 | 17 | 0.2 | 0 |
| MFF | MFF | Q9GZY8 | Mitochondrial fission factor | chr2 | GO:0008637 | Not Cancer Driver | No | 59 | 0.173 | 264 | 47 | 0.178 | 0 |
| MTRNR2L5 | MTRNR2L5 | P0CJ72 | Humanin-like 5 | chr10 | GO:0008637 | Not Cancer Driver | No | 1 | 0.042 | 0 | 0 | 0.0 | 0 |
| NAIF1 | NAIF1 | Q69YI7 | Nuclear apoptosis-inducing factor 1 | chr9 | GO:0008637 | Not Cancer Driver | No | 46 | 0.141 | 219 | 27 | 0.123 | 0 |
| NDUFS1_ENST00000449699 | NDUFS1 | P28331 | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial | chr2 | GO:0008637 | Not Cancer Driver | No | 81 | 0.111 | 40 | 3 | 0.075 | 2 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0008637 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| NPTX1 | NPTX1 | Q15818 | Neuronal pentraxin-1 | chr17 | GO:0008637 | Not Cancer Driver | No | 63 | 0.146 | 185 | 24 | 0.13 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | GO:0008637 | Not Cancer Driver | No | 2 | 0.037 | 23 | 1 | 0.043 | 0 |
| PPIF | PPIF | P30405 | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | chr10 | GO:0008637 | Not Cancer Driver | No | 19 | 0.092 | 43 | 4 | 0.093 | 0 |
| PPP2CB | PPP2CB | P62714 | Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform | chr8 | GO:0008637 | Not Cancer Driver | No | 37 | 0.12 | 12 | 0 | 0.0 | 0 |
| RHOT1_ENST00000333942 | RHOT1 | Q8IXI2 | Mitochondrial Rho GTPase 1 | chr17 | GO:0008637 | Not Cancer Driver | No | 56 | 0.091 | 46 | 2 | 0.043 | 0 |
| RHOT2 | RHOT2 | Q8IXI1 | Mitochondrial Rho GTPase 2 | chr16 | GO:0008637 | Not Cancer Driver | No | 52 | 0.084 | 79 | 5 | 0.063 | 0 |
| RTL10_ENST00000407472 | RTL10 | Q7L3V2 | Protein Bop | chr22 | GO:0008637 | Not Cancer Driver | No | 52 | 0.143 | 196 | 31 | 0.158 | 0 |
| SFN | SFN | P31947 | 14-3-3 protein sigma | chr1 | GO:0008637 | Not Cancer Driver | No | 27 | 0.109 | 75 | 9 | 0.12 | 0 |
| SLC25A4 | SLC25A4 | P12235 | ADP/ATP translocase 1 | chr4 | GO:0008637 | Not Cancer Driver | No | 24 | 0.081 | 0 | 0 | 0.0 | 9 |
| SOD2_ENST00000367055 | SOD2 | P04179 | Superoxide dismutase [Mn], mitochondrial | chr6 | GO:0008637 | Not Cancer Driver | No | 32 | 0.144 | 25 | 5 | 0.2 | 0 |
| STPG1 | STPG1 | Q5TH74 | O(6)-methylguanine-induced apoptosis 2 | chr1 | GO:0008637 | Not Cancer Driver | No | 45 | 0.135 | 171 | 23 | 0.135 | 0 |
| THEM4 | THEM4 | Q5T1C6 | Acyl-coenzyme A thioesterase THEM4 | chr1 | GO:0008637 | Not Cancer Driver | No | 19 | 0.079 | 14 | 0 | 0.0 | 0 |
| TIMM50_ENST00000607714 | TIMM50 | Q3ZCQ8 | Mitochondrial import inner membrane translocase subunit TIM50 | chr19 | GO:0008637 | Not Cancer Driver | No | 39 | 0.11 | 75 | 7 | 0.093 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0008637 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| VDAC2_ENST00000543351 | VDAC2 | P45880 | Voltage-dependent anion-selective channel protein 2 | chr10 | GO:0008637 | Not Cancer Driver | No | 35 | 0.119 | 9 | 1 | 0.111 | 0 |
| VPS35 | VPS35 | Q96QK1 | Vacuolar protein sorting-associated protein 35 | chr16 | GO:0008637 | Not Cancer Driver | No | 68 | 0.085 | 99 | 9 | 0.091 | 1 |