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Total number of protein in "GO:0008630" GO term:  43

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0008630 Census, Compendium Yes 139 0.123 604 73 0.121 2
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0008630 Census, Compendium Yes 469 0.153 225 39 0.173 41
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0008630 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0008630 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0008630 Census Yes 30 0.156 39 2 0.051 0
BCL2A1 BCL2A1 Q16548 Bcl-2-related protein A1 chr15 GO:0008630 Not Cancer Driver No 28 0.16 0 0 0.0 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0008630 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L10_ENST00000260442 BCL2L10 Q9HD36 Bcl-2-like protein 10 chr15 GO:0008630 Not Cancer Driver No 10 0.049 34 1 0.029 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0008630 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0008630 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0008630 Census, Compendium Yes 24 0.1 72 5 0.069 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0008630 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRCA1_ENST00000357654 BRCA1 P38398 Breast cancer type 1 susceptibility protein chr17 GO:0008630 Census, Compendium Yes 224 0.12 1458 174 0.119 35
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0008630 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0008630 Census Yes 49 0.118 71 7 0.099 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0008630 Census, Compendium Yes 335 0.617 157 130 0.828 13
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0008630 Not Cancer Driver No 19 0.087 23 1 0.043 0
CRIP1_ENST00000409393 CRIP1 P50238 Cysteine-rich protein 1 chr14 GO:0008630 Not Cancer Driver No 6 0.078 8 1 0.125 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0008630 Not Cancer Driver No 49 0.112 272 23 0.085 0
EPHA2 EPHA2 P29317 Ephrin type-A receptor 2 chr1 GO:0008630 Compendium Yes 171 0.175 187 39 0.209 3
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0008630 Not Cancer Driver No 211 0.141 829 117 0.141 9
FNIP2 FNIP2 Q9P278 Folliculin-interacting protein 2 chr4 GO:0008630 Not Cancer Driver No 119 0.107 555 71 0.128 0
HIC1 HIC1 Q14526 Hypermethylated in cancer 1 protein chr17 GO:0008630 Not Cancer Driver No 24 0.033 361 6 0.017 0
HMOX1 HMOX1 P09601 Heme oxygenase 1 chr22 GO:0008630 Not Cancer Driver No 46 0.16 81 13 0.16 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0008630 Compendium Yes 44 0.096 127 9 0.071 2
IKBKE IKBKE Q14164 Inhibitor of nuclear factor kappa-B kinase subunit epsilon chr1 GO:0008630 Not Cancer Driver No 108 0.151 76 13 0.171 0
MAEL MAEL Q96JY0 Protein maelstrom homolog chr1 GO:0008630 Not Cancer Driver No 126 0.29 114 35 0.307 0
MCL1 MCL1 Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 chr1 GO:0008630 Not Cancer Driver No 30 0.086 203 21 0.103 0
MLH1 MLH1 P40692 DNA mismatch repair protein Mlh1 chr3 GO:0008630 Census Yes 92 0.122 208 22 0.106 85
MOAP1_ENST00000298894 MOAP1 Q96BY2 Modulator of apoptosis 1 chr14 GO:0008630 Not Cancer Driver No 48 0.137 47 8 0.17 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0008630 Census Yes 154 0.113 386 41 0.106 6
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0008630 Not Cancer Driver No 155 0.172 685 120 0.175 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0008630 Census, Compendium Yes 154 0.213 268 61 0.228 2
PML PML P29590 Protein PML chr15 GO:0008630 Census, Compendium Yes 112 0.127 312 34 0.109 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0008630 Not Cancer Driver No 43 0.128 87 11 0.126 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0008630 Not Cancer Driver No 538 0.13 421 61 0.145 2
SFN SFN P31947 14-3-3 protein sigma chr1 GO:0008630 Not Cancer Driver No 27 0.109 75 9 0.12 0
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0008630 Not Cancer Driver No 32 0.144 25 5 0.2 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0008630 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF1A TNFRSF1A P19438 Tumor necrosis factor receptor superfamily member 1A chr12 GO:0008630 Not Cancer Driver No 58 0.127 111 15 0.135 12
TNFRSF1B TNFRSF1B P20333 Tumor necrosis factor receptor superfamily member 1B chr1 GO:0008630 Not Cancer Driver No 48 0.104 229 28 0.122 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0008630 Not Cancer Driver No 149 0.143 795 105 0.132 0
TP73 TP73 O15350 Tumor protein p73 chr1 GO:0008630 Not Cancer Driver No 82 0.129 443 55 0.124 0