Total number of protein in "GO:0008593" GO term: 60
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AAK1 | AAK1 | Q2M2I8 | AP2-associated protein kinase 1 | chr2 | GO:0008593 | Not Cancer Driver | No | 109 | 0.113 | 654 | 70 | 0.107 | 0 |
| ADAM10 | ADAM10 | O14672 | Disintegrin and metalloproteinase domain-containing protein 10 | chr15 | GO:0008593 | Not Cancer Driver | No | 88 | 0.118 | 156 | 20 | 0.128 | 4 |
| ASCL1 | ASCL1 | P50553 | Achaete-scute homolog 1 | chr12 | GO:0008593 | Not Cancer Driver | No | 33 | 0.14 | 182 | 24 | 0.132 | 0 |
| BMP2K | BMP2K | Q9NSY1 | BMP-2-inducible protein kinase | chr4 | GO:0008593 | Not Cancer Driver | No | 124 | 0.107 | 827 | 89 | 0.108 | 0 |
| CCN3 | CCN3 | P48745 | CCN family member 3 | chr8 | GO:0008593 | Not Cancer Driver | No | 66 | 0.185 | 19 | 1 | 0.053 | 0 |
| CD46_ENST00000358170 | CD46 | P15529 | Membrane cofactor protein | chr1 | GO:0008593 | Not Cancer Driver | No | 53 | 0.135 | 52 | 4 | 0.077 | 5 |
| CNTN6_ENST00000350110 | CNTN6 | Q9UQ52 | Contactin-6 | chr3 | GO:0008593 | Not Cancer Driver | No | 330 | 0.321 | 173 | 59 | 0.341 | 0 |
| DLL1 | DLL1 | O00548 | Delta-like protein 1 | chr6 | GO:0008593 | Not Cancer Driver | No | 115 | 0.159 | 145 | 24 | 0.166 | 1 |
| DLL4 | DLL4 | Q9NR61 | Delta-like protein 4 | chr15 | GO:0008593 | Not Cancer Driver | No | 75 | 0.109 | 73 | 15 | 0.205 | 7 |
| DTX1 | DTX1 | Q86Y01 | E3 ubiquitin-protein ligase DTX1 | chr12 | GO:0008593 | Compendium | Yes | 107 | 0.173 | 304 | 43 | 0.141 | 0 |
| ENHO | ENHO | Q6UWT2 | Adropin | chr9 | GO:0008593 | Not Cancer Driver | No | 12 | 0.158 | 32 | 5 | 0.156 | 0 |
| EPN2 | EPN2 | O95208 | Epsin-2 | chr17 | GO:0008593 | Not Cancer Driver | No | 73 | 0.114 | 543 | 61 | 0.112 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0008593 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| GALNT11_ENST00000430044 | GALNT11 | Q8NCW6 | Polypeptide N-acetylgalactosaminyltransferase 11 | chr7 | GO:0008593 | Not Cancer Driver | No | 73 | 0.12 | 91 | 18 | 0.198 | 0 |
| GAS2 | GAS2 | O43903 | Growth arrest-specific protein 2 | chr11 | GO:0008593 | Not Cancer Driver | No | 73 | 0.233 | 92 | 16 | 0.174 | 0 |
| GATA5 | GATA5 | Q9BWX5 | Transcription factor GATA-5 | chr20 | GO:0008593 | Not Cancer Driver | No | 40 | 0.101 | 268 | 24 | 0.09 | 9 |
| GSX2 | GSX2 | Q9BZM3 | GS homeobox 2 | chr4 | GO:0008593 | Not Cancer Driver | No | 44 | 0.145 | 210 | 26 | 0.124 | 1 |
| HES1 | HES1 | Q14469 | Transcription factor HES-1 | chr3 | GO:0008593 | Not Cancer Driver | No | 37 | 0.132 | 226 | 32 | 0.142 | 0 |
| HES5 | HES5 | Q5TA89 | Transcription factor HES-5 | chr1 | GO:0008593 | Not Cancer Driver | No | 1 | 0.006 | 73 | 0 | 0.0 | 0 |
| IL6ST_ENST00000336909 | IL6ST | P40189 | Interleukin-6 receptor subunit beta | chr5 | GO:0008593 | Census, Compendium | Yes | 102 | 0.111 | 315 | 40 | 0.127 | 2 |
| ITGB1BP1_ENST00000355346 | ITGB1BP1 | O14713 | Integrin beta-1-binding protein 1 | chr2 | GO:0008593 | Not Cancer Driver | No | 26 | 0.13 | 58 | 11 | 0.19 | 0 |
| JAG1 | JAG1 | P78504 | Protein jagged-1 | chr20 | GO:0008593 | Not Cancer Driver | No | 182 | 0.149 | 172 | 20 | 0.116 | 52 |
| JAG2 | JAG2 | Q9Y219 | Protein jagged-2 | chr14 | GO:0008593 | Not Cancer Driver | No | 126 | 0.102 | 158 | 24 | 0.152 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0008593 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| LFNG | LFNG | Q8NES3 | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe | chr7 | GO:0008593 | Not Cancer Driver | No | 37 | 0.098 | 65 | 1 | 0.015 | 1 |
| LLGL1 | LLGL1 | Q15334 | Lethal(2) giant larvae protein homolog 1 | chr17 | GO:0008593 | Not Cancer Driver | No | 101 | 0.095 | 265 | 12 | 0.045 | 0 |
| LLGL2 | LLGL2 | Q6P1M3 | LLGL scribble cell polarity complex component 2 | chr17 | GO:0008593 | Not Cancer Driver | No | 120 | 0.118 | 266 | 26 | 0.098 | 0 |
| MESP1 | MESP1 | Q9BRJ9 | Mesoderm posterior protein 1 | chr15 | GO:0008593 | Not Cancer Driver | No | 8 | 0.03 | 247 | 7 | 0.028 | 0 |
| MFNG | MFNG | O00587 | Beta-1,3-N-acetylglucosaminyltransferase manic fringe | chr22 | GO:0008593 | Not Cancer Driver | No | 37 | 0.115 | 29 | 4 | 0.138 | 0 |
| NEPRO | NEPRO | Q6NW34 | Nucleolus and neural progenitor protein | chr3 | GO:0008593 | Not Cancer Driver | No | 62 | 0.109 | 147 | 28 | 0.19 | 0 |
| NOD2 | NOD2 | Q9HC29 | Nucleotide-binding oligomerization domain-containing protein 2 | chr16 | GO:0008593 | Not Cancer Driver | No | 169 | 0.163 | 40 | 4 | 0.1 | 15 |
| NOS3 | NOS3 | P29474 | Nitric oxide synthase, endothelial | chr7 | GO:0008593 | Not Cancer Driver | No | 168 | 0.14 | 347 | 38 | 0.11 | 0 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0008593 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NOTCH2NLA | NOTCH2NLA | Q7Z3S9 | Notch homolog 2 N-terminal-like protein A | chr1 | GO:0008593 | Not Cancer Driver | No | 68 | 0.288 | 17 | 2 | 0.118 | 0 |
| NRARP | NRARP | Q7Z6K4 | Notch-regulated ankyrin repeat-containing protein | chr9 | GO:0008593 | Not Cancer Driver | No | 9 | 0.079 | 11 | 1 | 0.091 | 0 |
| PDCD10_ENST00000473645 | PDCD10 | Q9BUL8 | Programmed cell death protein 10 | chr3 | GO:0008593 | Not Cancer Driver | No | 32 | 0.151 | 25 | 4 | 0.16 | 0 |
| POFUT1 | POFUT1 | Q9H488 | GDP-fucose protein O-fucosyltransferase 1 | chr20 | GO:0008593 | Not Cancer Driver | No | 56 | 0.144 | 17 | 2 | 0.118 | 0 |
| POGLUT1 | POGLUT1 | Q8NBL1 | Protein O-glucosyltransferase 1 | chr3 | GO:0008593 | Not Cancer Driver | No | 57 | 0.145 | 0 | 0 | 0.0 | 3 |
| POSTN | POSTN | Q15063 | Periostin | chr13 | GO:0008593 | Not Cancer Driver | No | 204 | 0.244 | 86 | 27 | 0.314 | 0 |
| PRAG1_ENST00000622241 | PRAG1 | Q86YV5 | Inactive tyrosine-protein kinase PRAG1 | chr8 | GO:0008593 | Not Cancer Driver | No | 193 | 0.137 | 988 | 150 | 0.152 | 0 |
| PRKCI | PRKCI | P41743 | Protein kinase C iota type | chr3 | GO:0008593 | Not Cancer Driver | No | 110 | 0.185 | 120 | 16 | 0.133 | 0 |
| RFNG | RFNG | Q9Y644 | Beta-1,3-N-acetylglucosaminyltransferase radical fringe | chr17 | GO:0008593 | Not Cancer Driver | No | 22 | 0.066 | 92 | 5 | 0.054 | 0 |
| ROBO1 | ROBO1 | Q9Y6N7 | Roundabout homolog 1 | chr3 | GO:0008593 | Not Cancer Driver | No | 353 | 0.214 | 1122 | 234 | 0.209 | 0 |
| ROBO2_ENST00000461745 | ROBO2 | Q9HCK4 | Roundabout homolog 2 | chr3 | GO:0008593 | Census | Yes | 407 | 0.295 | 874 | 259 | 0.296 | 2 |
| SLC35C2_ENST00000372227 | SLC35C2 | Q9NQQ7 | Solute carrier family 35 member C2 | chr20 | GO:0008593 | Not Cancer Driver | No | 56 | 0.153 | 15 | 2 | 0.133 | 0 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0008593 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SREBF2 | SREBF2 | Q12772 | Sterol regulatory element-binding protein 2 | chr22 | GO:0008593 | Not Cancer Driver | No | 124 | 0.109 | 357 | 43 | 0.12 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0008593 | Census, Compendium | Yes | 110 | 0.143 | 152 | 15 | 0.099 | 19 |
| SYNJ2BP | SYNJ2BP | P57105 | Synaptojanin-2-binding protein | chr14 | GO:0008593 | Not Cancer Driver | No | 27 | 0.186 | 12 | 4 | 0.333 | 0 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0008593 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TM2D3 | TM2D3 | Q9BRN9 | TM2 domain-containing protein 3 | chr15 | GO:0008593 | Not Cancer Driver | No | 31 | 0.126 | 13 | 3 | 0.231 | 0 |
| TP63 | TP63 | Q9H3D4 | Tumor protein 63 | chr3 | GO:0008593 | Census, Compendium | Yes | 229 | 0.337 | 398 | 143 | 0.359 | 28 |
| TSPAN14_ENST00000372156 | TSPAN14 | Q8NG11 | Tetraspanin-14 | chr10 | GO:0008593 | Not Cancer Driver | No | 38 | 0.141 | 0 | 0 | 0.0 | 0 |
| TSPAN15 | TSPAN15 | O95858 | Tetraspanin-15 | chr10 | GO:0008593 | Not Cancer Driver | No | 29 | 0.099 | 0 | 0 | 0.0 | 0 |
| TSPAN5 | TSPAN5 | P62079 | Tetraspanin-5 | chr4 | GO:0008593 | Not Cancer Driver | No | 49 | 0.183 | 0 | 0 | 0.0 | 0 |
| TSPEAR_ENST00000613245 | TSPEAR | Q8WU66 | Thrombospondin-type laminin G domain and EAR repeat-containing protein | chr21 | GO:0008593 | Not Cancer Driver | No | 131 | 0.196 | 7 | 1 | 0.143 | 0 |
| WNT1 | WNT1 | P04628 | Proto-oncogene Wnt-1 | chr12 | GO:0008593 | Not Cancer Driver | No | 29 | 0.078 | 25 | 0 | 0.0 | 8 |
| YAP1_ENST00000282441 | YAP1 | P46937 | Transcriptional coactivator YAP1 | chr11 | GO:0008593 | Not Cancer Driver | No | 51 | 0.101 | 489 | 49 | 0.1 | 0 |
| YJEFN3 | YJEFN3 | A6XGL0 | YjeF N-terminal domain-containing protein 3 | chr19 | GO:0008593 | Not Cancer Driver | No | 35 | 0.117 | 56 | 5 | 0.089 | 0 |
| ZMIZ1 | ZMIZ1 | Q9ULJ6 | Zinc finger MIZ domain-containing protein 1 | chr10 | GO:0008593 | Not Cancer Driver | No | 148 | 0.139 | 762 | 111 | 0.146 | 5 |