Total number of protein in "GO:0008408" GO term: 35
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| APEX1_ENST00000555414 | APEX1 | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | chr14 | GO:0008408 | Not Cancer Driver | No | 34 | 0.107 | 103 | 14 | 0.136 | 0 |
| APEX2 | APEX2 | Q9UBZ4 | DNA-(apurinic or apyrimidinic site) endonuclease 2 | chrX | GO:0008408 | Not Cancer Driver | No | 66 | 0.127 | 148 | 14 | 0.095 | 0 |
| APLF | APLF | Q8IW19 | Aprataxin and PNK-like factor | chr2 | GO:0008408 | Not Cancer Driver | No | 64 | 0.125 | 407 | 57 | 0.14 | 0 |
| CNOT1 | CNOT1 | A5YKK6 | CCR4-NOT transcription complex subunit 1 | chr16 | GO:0008408 | Not Cancer Driver | No | 346 | 0.146 | 464 | 56 | 0.121 | 12 |
| CNOT2 | CNOT2 | Q9NZN8 | CCR4-NOT transcription complex subunit 2 | chr12 | GO:0008408 | Not Cancer Driver | No | 84 | 0.156 | 354 | 66 | 0.186 | 0 |
| CNOT6L | CNOT6L | Q96LI5 | CCR4-NOT transcription complex subunit 6-like | chr4 | GO:0008408 | Not Cancer Driver | No | 58 | 0.105 | 37 | 3 | 0.081 | 0 |
| CNOT6_ENST00000261951 | CNOT6 | Q9ULM6 | CCR4-NOT transcription complex subunit 6 | chr5 | GO:0008408 | Not Cancer Driver | No | 65 | 0.117 | 66 | 4 | 0.061 | 0 |
| CNOT7 | CNOT7 | Q9UIV1 | CCR4-NOT transcription complex subunit 7 | chr8 | GO:0008408 | Not Cancer Driver | No | 31 | 0.109 | 21 | 1 | 0.048 | 0 |
| CNOT8 | CNOT8 | Q9UFF9 | CCR4-NOT transcription complex subunit 8 | chr5 | GO:0008408 | Not Cancer Driver | No | 30 | 0.103 | 6 | 0 | 0.0 | 0 |
| ERI1_ENST00000519292 | ERI1 | Q8IV48 | 3'-5' exoribonuclease 1 | chr8 | GO:0008408 | Not Cancer Driver | No | 40 | 0.115 | 78 | 13 | 0.167 | 0 |
| EXD1_ENST00000314992 | EXD1 | Q8NHP7 | piRNA biogenesis protein EXD1 | chr15 | GO:0008408 | Not Cancer Driver | No | 85 | 0.165 | 173 | 26 | 0.15 | 0 |
| EXD2 | EXD2 | Q9NVH0 | Exonuclease 3'-5' domain-containing protein 2 | chr14 | GO:0008408 | Not Cancer Driver | No | 58 | 0.093 | 176 | 15 | 0.085 | 0 |
| EXD3 | EXD3 | Q8N9H8 | Exonuclease mut-7 homolog | chr9 | GO:0008408 | Not Cancer Driver | No | 103 | 0.118 | 188 | 30 | 0.16 | 0 |
| EXO5_ENST00000358527 | EXO5 | Q9H790 | Exonuclease V | chr1 | GO:0008408 | Not Cancer Driver | No | 39 | 0.105 | 36 | 3 | 0.083 | 0 |
| ISG20 | ISG20 | Q96AZ6 | Interferon-stimulated gene 20 kDa protein | chr15 | GO:0008408 | Not Cancer Driver | No | 20 | 0.11 | 6 | 0 | 0.0 | 0 |
| MEIOB_ENST00000397344 | MEIOB | Q8N635 | Meiosis-specific with OB domain-containing protein | chr16 | GO:0008408 | Not Cancer Driver | No | 37 | 0.084 | 21 | 2 | 0.095 | 1 |
| MRE11 | MRE11 | P49959 | Double-strand break repair protein MRE11 | chr11 | GO:0008408 | Not Cancer Driver | No | 84 | 0.119 | 292 | 35 | 0.12 | 1 |
| NOCT | NOCT | Q9UK39 | Nocturnin | chr4 | GO:0008408 | Not Cancer Driver | No | 33 | 0.077 | 89 | 3 | 0.034 | 0 |
| PAN2_ENST00000548043 | PAN2 | Q504Q3 | PAN2-PAN3 deadenylation complex catalytic subunit PAN2 | chr12 | GO:0008408 | Not Cancer Driver | No | 139 | 0.116 | 78 | 10 | 0.128 | 0 |
| PAN3 | PAN3 | Q58A45 | PAN2-PAN3 deadenylation complex subunit PAN3 | chr13 | GO:0008408 | Not Cancer Driver | No | 104 | 0.117 | 323 | 35 | 0.108 | 0 |
| PARN | PARN | O95453 | Poly(A)-specific ribonuclease PARN | chr16 | GO:0008408 | Not Cancer Driver | No | 71 | 0.111 | 197 | 22 | 0.112 | 2 |
| PDE12 | PDE12 | Q6L8Q7 | 2',5'-phosphodiesterase 12 | chr3 | GO:0008408 | Not Cancer Driver | No | 59 | 0.097 | 129 | 8 | 0.062 | 0 |
| PNLDC1_ENST00000610273 | PNLDC1 | Q8NA58 | Poly(A)-specific ribonuclease PNLDC1 | chr6 | GO:0008408 | Not Cancer Driver | No | 105 | 0.202 | 6 | 0 | 0.0 | 1 |
| POLE | POLE | Q07864 | DNA polymerase epsilon catalytic subunit A | chr12 | GO:0008408 | Census, Compendium | Yes | 409 | 0.179 | 239 | 44 | 0.184 | 3 |
| POLG_ENST00000442287 | POLG | P54098 | DNA polymerase subunit gamma-1 | chr15 | GO:0008408 | Census | Yes | 139 | 0.112 | 421 | 42 | 0.1 | 73 |
| RAD1 | RAD1 | O60671 | Cell cycle checkpoint protein RAD1 | chr5 | GO:0008408 | Not Cancer Driver | No | 29 | 0.103 | 4 | 1 | 0.25 | 0 |
| RAD50 | RAD50 | Q92878 | DNA repair protein RAD50 | chr5 | GO:0008408 | Not Cancer Driver | No | 157 | 0.12 | 730 | 84 | 0.115 | 0 |
| RAD9A | RAD9A | Q99638 | Cell cycle checkpoint control protein RAD9A | chr11 | GO:0008408 | Not Cancer Driver | No | 34 | 0.087 | 135 | 7 | 0.052 | 0 |
| REXO2 | REXO2 | Q9Y3B8 | Oligoribonuclease, mitochondrial | chr11 | GO:0008408 | Not Cancer Driver | No | 19 | 0.08 | 43 | 4 | 0.093 | 0 |
| REXO4 | REXO4 | Q9GZR2 | RNA exonuclease 4 | chr9 | GO:0008408 | Not Cancer Driver | No | 34 | 0.081 | 298 | 26 | 0.087 | 0 |
| TOE1 | TOE1 | Q96GM8 | Target of EGR1 protein 1 | chr1 | GO:0008408 | Not Cancer Driver | No | 44 | 0.086 | 210 | 22 | 0.105 | 10 |
| TREX1_ENST00000625293 | TREX1 | Q9NSU2 | Three-prime repair exonuclease 1 | chr3 | GO:0008408 | Not Cancer Driver | No | 26 | 0.083 | 98 | 10 | 0.102 | 18 |
| TRIR | TRIR | Q9BQ61 | Telomerase RNA component interacting RNase | chr19 | GO:0008408 | Not Cancer Driver | No | 17 | 0.097 | 176 | 17 | 0.097 | 0 |
| USB1 | USB1 | Q9BQ65 | U6 snRNA phosphodiesterase 1 | chr16 | GO:0008408 | Not Cancer Driver | No | 28 | 0.106 | 76 | 5 | 0.066 | 0 |
| WRN | WRN | Q14191 | Werner syndrome ATP-dependent helicase | chr8 | GO:0008408 | Census, Compendium | Yes | 164 | 0.115 | 373 | 41 | 0.11 | 2 |