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Total number of protein in "GO:0008237" GO term:  120

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0008237 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0008237 Not Cancer Driver No 104 0.129 68 5 0.074 0
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0008237 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM11 ADAM11 O75078 Disintegrin and metalloproteinase domain-containing protein 11 chr17 GO:0008237 Not Cancer Driver No 98 0.127 163 17 0.104 0
ADAM12 ADAM12 O43184 Disintegrin and metalloproteinase domain-containing protein 12 chr10 GO:0008237 Not Cancer Driver No 165 0.182 205 37 0.18 0
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0008237 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM17 ADAM17 P78536 Disintegrin and metalloproteinase domain-containing protein 17 chr2 GO:0008237 Not Cancer Driver No 80 0.097 182 17 0.093 0
ADAM18 ADAM18 Q9Y3Q7 Disintegrin and metalloproteinase domain-containing protein 18 chr8 GO:0008237 Not Cancer Driver No 224 0.303 4 2 0.5 0
ADAM19_ENST00000517905 ADAM19 Q9H013 Disintegrin and metalloproteinase domain-containing protein 19 chr5 GO:0008237 Not Cancer Driver No 172 0.18 370 77 0.208 0
ADAM2 ADAM2 Q99965 Disintegrin and metalloproteinase domain-containing protein 2 chr8 GO:0008237 Not Cancer Driver No 194 0.264 18 4 0.222 0
ADAM21 ADAM21 Q9UKJ8 Disintegrin and metalloproteinase domain-containing protein 21 chr14 GO:0008237 Not Cancer Driver No 167 0.231 4 1 0.25 0
ADAM23 ADAM23 O75077 Disintegrin and metalloproteinase domain-containing protein 23 chr2 GO:0008237 Not Cancer Driver No 175 0.21 162 26 0.16 0
ADAM28 ADAM28 Q9UKQ2 Disintegrin and metalloproteinase domain-containing protein 28 chr8 GO:0008237 Not Cancer Driver No 193 0.249 123 24 0.195 0
ADAM29_ENST00000404450 ADAM29 Q9UKF5 Disintegrin and metalloproteinase domain-containing protein 29 chr4 GO:0008237 Not Cancer Driver No 257 0.313 124 39 0.315 0
ADAM30 ADAM30 Q9UKF2 Disintegrin and metalloproteinase domain-containing protein 30 chr1 GO:0008237 Not Cancer Driver No 133 0.168 73 12 0.164 0
ADAM7 ADAM7 Q9H2U9 Disintegrin and metalloproteinase domain-containing protein 7 chr8 GO:0008237 Not Cancer Driver No 241 0.32 55 22 0.4 0
ADAM8 ADAM8 P78325 Disintegrin and metalloproteinase domain-containing protein 8 chr10 GO:0008237 Not Cancer Driver No 82 0.1 230 13 0.057 0
ADAM9 ADAM9 Q13443 Disintegrin and metalloproteinase domain-containing protein 9 chr8 GO:0008237 Not Cancer Driver No 86 0.105 129 13 0.101 0
ADAMTS1 ADAMTS1 Q9UHI8 A disintegrin and metalloproteinase with thrombospondin motifs 1 chr21 GO:0008237 Not Cancer Driver No 135 0.14 272 32 0.118 0
ADAMTS13 ADAMTS13 Q76LX8 A disintegrin and metalloproteinase with thrombospondin motifs 13 chr9 GO:0008237 Not Cancer Driver No 172 0.121 285 35 0.123 43
ADAMTS2 ADAMTS2 O95450 A disintegrin and metalloproteinase with thrombospondin motifs 2 chr5 GO:0008237 Not Cancer Driver No 298 0.246 304 79 0.26 0
ADAMTS4 ADAMTS4 O75173 A disintegrin and metalloproteinase with thrombospondin motifs 4 chr1 GO:0008237 Not Cancer Driver No 134 0.16 159 27 0.17 0
ADAMTS5 ADAMTS5 Q9UNA0 A disintegrin and metalloproteinase with thrombospondin motifs 5 chr21 GO:0008237 Not Cancer Driver No 227 0.244 148 33 0.223 0
ADAMTS6 ADAMTS6 Q9UKP5 A disintegrin and metalloproteinase with thrombospondin motifs 6 chr5 GO:0008237 Not Cancer Driver No 166 0.149 75 11 0.147 0
ADAMTS7 ADAMTS7 Q9UKP4 A disintegrin and metalloproteinase with thrombospondin motifs 7 chr15 GO:0008237 Not Cancer Driver No 244 0.145 640 100 0.156 0
ADAMTS8 ADAMTS8 Q9UP79 A disintegrin and metalloproteinase with thrombospondin motifs 8 chr11 GO:0008237 Not Cancer Driver No 133 0.15 204 26 0.127 0
ADAMTS9 ADAMTS9 Q9P2N4 A disintegrin and metalloproteinase with thrombospondin motifs 9 chr3 GO:0008237 Not Cancer Driver No 288 0.149 235 38 0.162 0
AEBP1 AEBP1 Q8IUX7 Adipocyte enhancer-binding protein 1 chr7 GO:0008237 Not Cancer Driver No 175 0.151 689 102 0.148 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 GO:0008237 Not Cancer Driver No 72 0.09 162 10 0.062 22
AGBL1_ENST00000441037 AGBL1 Q96MI9 Cytosolic carboxypeptidase 4 chr15 GO:0008237 Not Cancer Driver No 258 0.232 165 45 0.273 1
AGBL2 AGBL2 Q5U5Z8 Cytosolic carboxypeptidase 2 chr11 GO:0008237 Not Cancer Driver No 117 0.13 246 29 0.118 0
AGBL4 AGBL4 Q5VU57 Cytosolic carboxypeptidase 6 chr1 GO:0008237 Not Cancer Driver No 65 0.129 72 2 0.028 0
AGBL5 AGBL5 Q8NDL9 Cytosolic carboxypeptidase-like protein 5 chr2 GO:0008237 Not Cancer Driver No 127 0.143 487 74 0.152 2
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 GO:0008237 Not Cancer Driver No 158 0.129 321 42 0.131 4
AMZ1 AMZ1 Q400G9 Archaemetzincin-1 chr7 GO:0008237 Not Cancer Driver No 78 0.157 147 18 0.122 0
AMZ2_ENST00000577866 AMZ2 Q86W34 Archaemetzincin-2 chr17 GO:0008237 Not Cancer Driver No 48 0.133 37 4 0.108 0
ANPEP ANPEP P15144 Aminopeptidase N chr15 GO:0008237 Not Cancer Driver No 175 0.181 109 26 0.239 0
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 GO:0008237 Not Cancer Driver No 119 0.121 154 25 0.162 3
BRCC3 BRCC3 P46736 Lys-63-specific deubiquitinase BRCC36 chrX GO:0008237 Not Cancer Driver No 39 0.123 74 7 0.095 0
C9orf3 AOPEP Q8N6M6 Aminopeptidase O chr9 GO:0008237 Not Cancer Driver No 87 0.106 107 13 0.121 0
CHMP1A CHMP1A Q9HD42 Charged multivesicular body protein 1a chr16 GO:0008237 Not Cancer Driver No 18 0.092 110 6 0.055 0
CNDP1 CNDP1 Q96KN2 Beta-Ala-His dipeptidase chr18 GO:0008237 Not Cancer Driver No 104 0.205 26 3 0.115 0
CNDP2_ENST00000579847 CNDP2 Q96KP4 Cytosolic non-specific dipeptidase chr18 GO:0008237 Not Cancer Driver No 67 0.141 39 5 0.128 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0008237 Not Cancer Driver No 36 0.108 32 7 0.219 0
COPS6 COPS6 Q7L5N1 COP9 signalosome complex subunit 6 chr7 GO:0008237 Not Cancer Driver No 38 0.116 30 6 0.2 0
CPA1 CPA1 P15085 Carboxypeptidase A1 chr7 GO:0008237 Not Cancer Driver No 84 0.2 5 1 0.2 0
CPA2 CPA2 P48052 Carboxypeptidase A2 chr7 GO:0008237 Not Cancer Driver No 62 0.148 26 2 0.077 0
CPA3 CPA3 P15088 Mast cell carboxypeptidase A chr3 GO:0008237 Not Cancer Driver No 111 0.266 38 9 0.237 0
CPA4 CPA4 Q9UI42 Carboxypeptidase A4 chr7 GO:0008237 Not Cancer Driver No 76 0.181 59 12 0.203 0
CPA5_ENST00000461828 CPA5 Q8WXQ8 Carboxypeptidase A5 chr7 GO:0008237 Not Cancer Driver No 79 0.181 40 4 0.1 0
CPA6 CPA6 Q8N4T0 Carboxypeptidase A6 chr8 GO:0008237 Not Cancer Driver No 106 0.243 7 0 0.0 2
CPB1_ENST00000282957 CPB1 P15086 Carboxypeptidase B chr3 GO:0008237 Not Cancer Driver No 91 0.218 15 2 0.133 0
CPB2_ENST00000645658 CPB2 Q96IY4 Carboxypeptidase B2 chr13 GO:0008237 Not Cancer Driver No 59 0.139 2 0 0.0 0
CPD CPD O75976 Carboxypeptidase D chr17 GO:0008237 Not Cancer Driver No 131 0.095 476 45 0.095 0
CPE CPE P16870 Carboxypeptidase E chr4 GO:0008237 Not Cancer Driver No 98 0.206 127 24 0.189 0
CPM CPM P14384 Carboxypeptidase M chr12 GO:0008237 Not Cancer Driver No 65 0.147 16 2 0.125 0
CPN1 CPN1 P15169 Carboxypeptidase N catalytic chain chr10 GO:0008237 Not Cancer Driver No 98 0.214 124 27 0.218 1
CPO CPO Q8IVL8 Carboxypeptidase O chr2 GO:0008237 Not Cancer Driver No 62 0.166 16 2 0.125 0
CPQ CPQ Q9Y646 Carboxypeptidase Q chr8 GO:0008237 Not Cancer Driver No 110 0.233 3 0 0.0 0
CPXM1 CPXM1 Q96SM3 Probable carboxypeptidase X1 chr20 GO:0008237 Not Cancer Driver No 128 0.174 252 35 0.139 0
CPXM2 CPXM2 Q8N436 Inactive carboxypeptidase-like protein X2 chr10 GO:0008237 Not Cancer Driver No 198 0.262 259 64 0.247 0
CPZ CPZ Q66K79 Carboxypeptidase Z chr4 GO:0008237 Not Cancer Driver No 163 0.25 71 31 0.437 0
DNPEP_ENST00000273075 DNPEP Q9ULA0 Aspartyl aminopeptidase chr2 GO:0008237 Not Cancer Driver No 55 0.113 90 8 0.089 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0008237 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPEP2_ENST00000393847 DPEP2 Q9H4A9 Dipeptidase 2 chr16 GO:0008237 Not Cancer Driver No 66 0.136 73 4 0.055 0
DPEP3 DPEP3 Q9H4B8 Dipeptidase 3 chr16 GO:0008237 Not Cancer Driver No 72 0.148 105 14 0.133 0
DPP3 DPP3 Q9NY33 Dipeptidyl peptidase 3 chr11 GO:0008237 Not Cancer Driver No 96 0.13 64 11 0.172 0
ECEL1 ECEL1 O95672 Endothelin-converting enzyme-like 1 chr2 GO:0008237 Not Cancer Driver No 103 0.133 22 2 0.091 4
EIF3F_ENST00000309828 EIF3F O00303 Eukaryotic translation initiation factor 3 subunit F chr11 GO:0008237 Not Cancer Driver No 29 0.081 125 8 0.064 1
EIF3H EIF3H O15372 Eukaryotic translation initiation factor 3 subunit H chr8 GO:0008237 Not Cancer Driver No 37 0.105 109 12 0.11 0
ENPEP ENPEP Q07075 Glutamyl aminopeptidase chr4 GO:0008237 Compendium Yes 235 0.246 130 44 0.338 0
ERAP1_ENST00000443439 ERAP1 Q9NZ08 Endoplasmic reticulum aminopeptidase 1 chr5 GO:0008237 Not Cancer Driver No 78 0.083 70 2 0.029 0
ERAP2 ERAP2 Q6P179 Endoplasmic reticulum aminopeptidase 2 chr5 GO:0008237 Not Cancer Driver No 97 0.101 23 4 0.174 0
ERMP1 ERMP1 Q7Z2K6 Endoplasmic reticulum metallopeptidase 1 chr9 GO:0008237 Not Cancer Driver No 80 0.088 93 4 0.043 0
FOLH1 FOLH1 Q04609 Glutamate carboxypeptidase 2 chr11 GO:0008237 Not Cancer Driver No 200 0.267 43 13 0.302 0
LAP3 LAP3 P28838 Cytosol aminopeptidase chr4 GO:0008237 Not Cancer Driver No 59 0.114 99 14 0.141 0
LNPEP LNPEP Q9UIQ6 Leucyl-cystinyl aminopeptidase chr5 GO:0008237 Not Cancer Driver No 115 0.112 103 8 0.078 0
LTA4H LTA4H P09960 Leukotriene A-4 hydrolase chr12 GO:0008237 Not Cancer Driver No 59 0.097 39 6 0.154 0
LVRN LVRN Q6Q4G3 Aminopeptidase Q chr5 GO:0008237 Not Cancer Driver No 212 0.214 81 20 0.247 0
METAP1 METAP1 P53582 Methionine aminopeptidase 1 chr4 GO:0008237 Not Cancer Driver No 37 0.096 61 3 0.049 0
METAP1D METAP1D Q6UB28 Methionine aminopeptidase 1D, mitochondrial chr2 GO:0008237 Not Cancer Driver No 40 0.119 30 5 0.167 0
METAP2 METAP2 P50579 Methionine aminopeptidase 2 chr12 GO:0008237 Not Cancer Driver No 54 0.113 176 19 0.108 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0008237 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP15 MMP15 P51511 Matrix metalloproteinase-15 chr16 GO:0008237 Not Cancer Driver No 78 0.117 205 23 0.112 0
MMP16 MMP16 P51512 Matrix metalloproteinase-16 chr8 GO:0008237 Not Cancer Driver No 235 0.387 168 61 0.363 0
MMP17 MMP17 Q9ULZ9 Matrix metalloproteinase-17 chr12 GO:0008237 Not Cancer Driver No 93 0.154 241 26 0.108 0
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0008237 Not Cancer Driver No 123 0.186 29 6 0.207 2
MMP23B MMP23B O75900 Matrix metalloproteinase-23 chr1 GO:0008237 Not Cancer Driver No 3 0.008 35 0 0.0 0
MMP3 MMP3 P08254 Stromelysin-1 chr11 GO:0008237 Not Cancer Driver No 99 0.208 66 14 0.212 0
MMP7 MMP7 P09237 Matrilysin chr11 GO:0008237 Not Cancer Driver No 39 0.146 70 2 0.029 0
MMP9 MMP9 P14780 Matrix metalloproteinase-9 chr20 GO:0008237 Not Cancer Driver No 129 0.182 124 26 0.21 0
MYSM1 MYSM1 Q5VVJ2 Deubiquitinase MYSM1 chr1 GO:0008237 Not Cancer Driver No 78 0.094 345 26 0.075 1
NAALAD2 NAALAD2 Q9Y3Q0 N-acetylated-alpha-linked acidic dipeptidase 2 chr11 GO:0008237 Not Cancer Driver No 165 0.223 22 4 0.182 0
NAALADL1 NAALADL1 Q9UQQ1 Aminopeptidase NAALADL1 chr11 GO:0008237 Not Cancer Driver No 105 0.142 135 17 0.126 0
NAALADL2 NAALADL2 Q58DX5 Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 chr3 GO:0008237 Not Cancer Driver No 162 0.204 207 46 0.222 0
NCLN NCLN Q969V3 Nicalin chr19 GO:0008237 Not Cancer Driver No 42 0.075 38 4 0.105 0
NPEPL1 NPEPL1 Q8NDH3 Probable aminopeptidase NPEPL1 chr20 GO:0008237 Not Cancer Driver No 67 0.128 26 3 0.115 0
NPEPPS NPEPPS P55786 Puromycin-sensitive aminopeptidase chr17 GO:0008237 Compendium Yes 102 0.111 45 5 0.111 0
NUDT16_ENST00000521288 NUDT16 Q96DE0 U8 snoRNA-decapping enzyme chr3 GO:0008237 Not Cancer Driver No 29 0.149 8 1 0.125 0
PAPPA PAPPA Q13219 Pappalysin-1 chr9 GO:0008237 Not Cancer Driver No 370 0.227 239 37 0.155 0
PAPPA2 PAPPA2 Q9BXP8 Pappalysin-2 chr1 GO:0008237 Not Cancer Driver No 739 0.413 370 141 0.381 1
PEPD PEPD P12955 Xaa-Pro dipeptidase chr19 GO:0008237 Not Cancer Driver No 53 0.108 17 2 0.118 4
PITRM1_ENST00000224949 PITRM1 Q5JRX3 Presequence protease, mitochondrial chr10 GO:0008237 Not Cancer Driver No 122 0.118 220 26 0.118 2
PRPF8 PRPF8 Q6P2Q9 Pre-mRNA-processing-splicing factor 8 chr17 GO:0008237 Not Cancer Driver No 255 0.109 225 26 0.116 8
PSMD14 PSMD14 O00487 26S proteasome non-ATPase regulatory subunit 14 chr2 GO:0008237 Not Cancer Driver No 23 0.074 67 6 0.09 0
PSMD7 PSMD7 P51665 26S proteasome non-ATPase regulatory subunit 7 chr16 GO:0008237 Not Cancer Driver No 39 0.12 70 4 0.057 0
QPCT QPCT Q16769 Glutaminyl-peptide cyclotransferase chr2 GO:0008237 Not Cancer Driver No 44 0.122 41 3 0.073 0
QPCTL QPCTL Q9NXS2 Glutaminyl-peptide cyclotransferase-like protein chr19 GO:0008237 Not Cancer Driver No 42 0.11 22 1 0.045 0
RNPEP RNPEP Q9H4A4 Aminopeptidase B chr1 GO:0008237 Not Cancer Driver No 60 0.092 86 4 0.047 0
RNPEPL1 RNPEPL1 Q9HAU8 Aminopeptidase RNPEPL1 chr2 GO:0008237 Not Cancer Driver No 55 0.076 82 2 0.024 0
STAMBPL1_ENST00000371924 STAMBPL1 Q96FJ0 AMSH-like protease chr10 GO:0008237 Not Cancer Driver No 48 0.11 70 7 0.1 0
STAMBP_ENST00000339566 STAMBP O95630 STAM-binding protein chr2 GO:0008237 Not Cancer Driver No 51 0.12 139 16 0.115 6
TFR2_ENST00000223051 TFR2 Q9UP52 Transferrin receptor protein 2 chr7 GO:0008237 Not Cancer Driver No 94 0.117 168 20 0.119 3
TFRC_ENST00000392396 TFRC P02786 Transferrin receptor protein 1 chr3 GO:0008237 Census Yes 89 0.117 80 6 0.075 1
TRHDE TRHDE Q9UKU6 Thyrotropin-releasing hormone-degrading ectoenzyme chr12 GO:0008237 Not Cancer Driver No 346 0.338 104 11 0.106 0
VASH1 VASH1 Q7L8A9 Tubulinyl-Tyr carboxypeptidase 1 chr14 GO:0008237 Not Cancer Driver No 39 0.107 215 18 0.084 0
VASH2 VASH2 Q86V25 Tubulinyl-Tyr carboxypeptidase 2 chr1 GO:0008237 Not Cancer Driver No 32 0.09 106 9 0.085 0
XPNPEP2 XPNPEP2 O43895 Xaa-Pro aminopeptidase 2 chrX GO:0008237 Not Cancer Driver No 114 0.169 16 2 0.125 0
XPNPEP3 XPNPEP3 Q9NQH7 Xaa-Pro aminopeptidase 3 chr22 GO:0008237 Not Cancer Driver No 64 0.126 128 14 0.109 1
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0008237 Not Cancer Driver No 67 0.141 23 0 0.0 3