Total number of protein in "GO:0008234" GO term: 102
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADGB | ADGB | Q8N7X0 | Androglobin | chr6 | GO:0008234 | Not Cancer Driver | No | 141 | 0.085 | 706 | 68 | 0.096 | 0 |
| ATG4A | ATG4A | Q8WYN0 | Cysteine protease ATG4A | chrX | GO:0008234 | Not Cancer Driver | No | 54 | 0.136 | 53 | 0 | 0.0 | 0 |
| ATG4B | ATG4B | Q9Y4P1 | Cysteine protease ATG4B | chr2 | GO:0008234 | Not Cancer Driver | No | 34 | 0.087 | 13 | 2 | 0.154 | 0 |
| ATG4C_ENST00000371120 | ATG4C | Q96DT6 | Cysteine protease ATG4C | chr1 | GO:0008234 | Not Cancer Driver | No | 62 | 0.135 | 17 | 3 | 0.176 | 0 |
| ATG4D | ATG4D | Q86TL0 | Cysteine protease ATG4D | chr19 | GO:0008234 | Not Cancer Driver | No | 70 | 0.148 | 106 | 12 | 0.113 | 0 |
| ATXN3 | ATXN3 | P54252 | Ataxin-3 | chr14 | GO:0008234 | Not Cancer Driver | No | 46 | 0.127 | 181 | 24 | 0.133 | 0 |
| BLMH | BLMH | Q13867 | Bleomycin hydrolase | chr17 | GO:0008234 | Not Cancer Driver | No | 54 | 0.119 | 15 | 1 | 0.067 | 0 |
| BRCC3 | BRCC3 | P46736 | Lys-63-specific deubiquitinase BRCC36 | chrX | GO:0008234 | Not Cancer Driver | No | 39 | 0.123 | 74 | 7 | 0.095 | 0 |
| CAPN10 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | GO:0008234 | Not Cancer Driver | No | 87 | 0.129 | 52 | 6 | 0.115 | 0 |
| CAPN11 | CAPN11 | Q9UMQ6 | Calpain-11 | chr6 | GO:0008234 | Not Cancer Driver | No | 96 | 0.13 | 103 | 12 | 0.117 | 0 |
| CAPN12 | CAPN12 | Q6ZSI9 | Calpain-12 | chr19 | GO:0008234 | Not Cancer Driver | No | 83 | 0.115 | 62 | 9 | 0.145 | 0 |
| CAPN13 | CAPN13 | Q6MZZ7 | Calpain-13 | chr2 | GO:0008234 | Not Cancer Driver | No | 155 | 0.232 | 73 | 24 | 0.329 | 0 |
| CAPN14 | CAPN14 | A8MX76 | Calpain-14 | chr2 | GO:0008234 | Not Cancer Driver | No | 47 | 0.069 | 22 | 2 | 0.091 | 0 |
| CAPN15 | CAPN15 | O75808 | Calpain-15 | chr16 | GO:0008234 | Not Cancer Driver | No | 98 | 0.09 | 385 | 29 | 0.075 | 0 |
| CAPN1_ENST00000533129 | CAPN1 | P07384 | Calpain-1 catalytic subunit | chr11 | GO:0008234 | Not Cancer Driver | No | 68 | 0.095 | 32 | 2 | 0.062 | 1 |
| CAPN2 | CAPN2 | P17655 | Calpain-2 catalytic subunit | chr1 | GO:0008234 | Not Cancer Driver | No | 81 | 0.116 | 46 | 11 | 0.239 | 0 |
| CAPN3 | CAPN3 | P20807 | Calpain-3 | chr15 | GO:0008234 | Not Cancer Driver | No | 111 | 0.135 | 168 | 11 | 0.065 | 52 |
| CAPN5 | CAPN5 | O15484 | Calpain-5 | chr11 | GO:0008234 | Not Cancer Driver | No | 103 | 0.161 | 110 | 25 | 0.227 | 2 |
| CAPN6 | CAPN6 | Q9Y6Q1 | Calpain-6 | chrX | GO:0008234 | Not Cancer Driver | No | 156 | 0.243 | 19 | 8 | 0.421 | 0 |
| CAPN7 | CAPN7 | Q9Y6W3 | Calpain-7 | chr3 | GO:0008234 | Not Cancer Driver | No | 80 | 0.098 | 92 | 9 | 0.098 | 0 |
| CAPN8 | CAPN8 | A6NHC0 | Calpain-8 | chr1 | GO:0008234 | Not Cancer Driver | No | 36 | 0.051 | 76 | 6 | 0.079 | 0 |
| CAPN9 | CAPN9 | O14815 | Calpain-9 | chr1 | GO:0008234 | Not Cancer Driver | No | 110 | 0.159 | 81 | 17 | 0.21 | 0 |
| CAPNS1 | CAPNS1 | P04632 | Calpain small subunit 1 | chr19 | GO:0008234 | Not Cancer Driver | No | 30 | 0.112 | 58 | 5 | 0.086 | 0 |
| CAPNS2 | CAPNS2 | Q96L46 | Calpain small subunit 2 | chr16 | GO:0008234 | Not Cancer Driver | No | 21 | 0.085 | 56 | 5 | 0.089 | 0 |
| CASP1 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0008234 | Not Cancer Driver | No | 79 | 0.196 | 87 | 18 | 0.207 | 0 |
| CASP10_ENST00000272879 | CASP10 | Q92851 | Caspase-10 | chr2 | GO:0008234 | Not Cancer Driver | No | 57 | 0.109 | 126 | 17 | 0.135 | 3 |
| CASP12 | CASP12 | Q6UXS9 | Inactive caspase-12 | chr11 | GO:0008234 | Not Cancer Driver | No | 12 | 0.035 | 31 | 1 | 0.032 | 0 |
| CASP14 | CASP14 | P31944 | Caspase-14 | chr19 | GO:0008234 | Not Cancer Driver | No | 50 | 0.207 | 84 | 13 | 0.155 | 0 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0008234 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0008234 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CASP4 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0008234 | Not Cancer Driver | No | 56 | 0.149 | 102 | 14 | 0.137 | 0 |
| CASP5_ENST00000260315 | CASP5 | P51878 | Caspase-5 | chr11 | GO:0008234 | Not Cancer Driver | No | 103 | 0.237 | 61 | 17 | 0.279 | 0 |
| CASP6 | CASP6 | P55212 | Caspase-6 | chr4 | GO:0008234 | Not Cancer Driver | No | 28 | 0.096 | 24 | 4 | 0.167 | 0 |
| CASP7_ENST00000345633 | CASP7 | P55210 | Caspase-7 | chr10 | GO:0008234 | Not Cancer Driver | No | 38 | 0.125 | 73 | 10 | 0.137 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0008234 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0008234 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0008234 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
| COPS4_ENST00000264389 | COPS4 | Q9BT78 | COP9 signalosome complex subunit 4 | chr4 | GO:0008234 | Not Cancer Driver | No | 50 | 0.123 | 13 | 0 | 0.0 | 0 |
| COPS5 | COPS5 | Q92905 | COP9 signalosome complex subunit 5 | chr8 | GO:0008234 | Not Cancer Driver | No | 36 | 0.108 | 32 | 7 | 0.219 | 0 |
| COPS6 | COPS6 | Q7L5N1 | COP9 signalosome complex subunit 6 | chr7 | GO:0008234 | Not Cancer Driver | No | 38 | 0.116 | 30 | 6 | 0.2 | 0 |
| CTSB | CTSB | P07858 | Cathepsin B | chr8 | GO:0008234 | Not Cancer Driver | No | 41 | 0.121 | 7 | 2 | 0.286 | 0 |
| CTSC | CTSC | P53634 | Dipeptidyl peptidase 1 | chr11 | GO:0008234 | Not Cancer Driver | No | 64 | 0.138 | 19 | 5 | 0.263 | 29 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0008234 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| CTSK | CTSK | P43235 | Cathepsin K | chr1 | GO:0008234 | Not Cancer Driver | No | 36 | 0.109 | 24 | 4 | 0.167 | 6 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | GO:0008234 | Not Cancer Driver | No | 47 | 0.141 | 34 | 4 | 0.118 | 0 |
| CTSV | CTSV | O60911 | Cathepsin L2 | chr9 | GO:0008234 | Not Cancer Driver | No | 55 | 0.165 | 7 | 1 | 0.143 | 0 |
| CTSW | CTSW | P56202 | Cathepsin W | chr11 | GO:0008234 | Not Cancer Driver | No | 58 | 0.154 | 59 | 10 | 0.169 | 0 |
| CTSZ | CTSZ | Q9UBR2 | Cathepsin Z | chr20 | GO:0008234 | Not Cancer Driver | No | 30 | 0.099 | 10 | 0 | 0.0 | 0 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0008234 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| DESI1 | DESI1 | Q6ICB0 | Desumoylating isopeptidase 1 | chr22 | GO:0008234 | Not Cancer Driver | No | 23 | 0.137 | 34 | 6 | 0.176 | 0 |
| DESI2 | DESI2 | Q9BSY9 | Deubiquitinase DESI2 | chr1 | GO:0008234 | Not Cancer Driver | No | 24 | 0.124 | 36 | 8 | 0.222 | 0 |
| EIF3F_ENST00000309828 | EIF3F | O00303 | Eukaryotic translation initiation factor 3 subunit F | chr11 | GO:0008234 | Not Cancer Driver | No | 29 | 0.081 | 125 | 8 | 0.064 | 1 |
| EIF3H | EIF3H | O15372 | Eukaryotic translation initiation factor 3 subunit H | chr8 | GO:0008234 | Not Cancer Driver | No | 37 | 0.105 | 109 | 12 | 0.11 | 0 |
| ESPL1 | ESPL1 | Q14674 | Separin | chr12 | GO:0008234 | Not Cancer Driver | No | 211 | 0.1 | 380 | 39 | 0.103 | 0 |
| GGH | GGH | Q92820 | Gamma-glutamyl hydrolase | chr8 | GO:0008234 | Not Cancer Driver | No | 46 | 0.145 | 5 | 0 | 0.0 | 0 |
| GPAA1 | GPAA1 | O43292 | Glycosylphosphatidylinositol anchor attachment 1 protein | chr8 | GO:0008234 | Not Cancer Driver | No | 55 | 0.089 | 20 | 3 | 0.15 | 5 |
| HINT1 | HINT1 | P49773 | Adenosine 5'-monophosphoramidase HINT1 | chr5 | GO:0008234 | Not Cancer Driver | No | 11 | 0.087 | 6 | 0 | 0.0 | 6 |
| MINDY1_ENST00000622754 | MINDY1 | Q8N5J2 | Ubiquitin carboxyl-terminal hydrolase MINDY-1 | chr1 | GO:0008234 | Not Cancer Driver | No | 61 | 0.13 | 219 | 33 | 0.151 | 0 |
| MINDY2 | MINDY2 | Q8NBR6 | Ubiquitin carboxyl-terminal hydrolase MINDY-2 | chr15 | GO:0008234 | Not Cancer Driver | No | 53 | 0.085 | 372 | 34 | 0.091 | 0 |
| MINDY3 | MINDY3 | Q9H8M7 | Ubiquitin carboxyl-terminal hydrolase MINDY-3 | chr10 | GO:0008234 | Not Cancer Driver | No | 73 | 0.164 | 17 | 2 | 0.118 | 0 |
| MINDY4 | MINDY4 | Q4G0A6 | Probable ubiquitin carboxyl-terminal hydrolase MINDY-4 | chr7 | GO:0008234 | Not Cancer Driver | No | 102 | 0.135 | 307 | 39 | 0.127 | 0 |
| MINDY4B | MINDY4B | A8MYZ0 | Inactive ubiquitin carboxyl-terminal hydrolase MINDY-4B | chr3 | GO:0008234 | Not Cancer Driver | No | 1 | 0.002 | 90 | 0 | 0.0 | 0 |
| MYSM1 | MYSM1 | Q5VVJ2 | Deubiquitinase MYSM1 | chr1 | GO:0008234 | Not Cancer Driver | No | 78 | 0.094 | 345 | 26 | 0.075 | 1 |
| OTUB1_ENST00000428192 | OTUB1 | Q96FW1 | Ubiquitin thioesterase OTUB1 | chr11 | GO:0008234 | Not Cancer Driver | No | 31 | 0.114 | 33 | 2 | 0.061 | 0 |
| OTUD4_ENST00000447906 | OTUD4 | Q01804 | OTU domain-containing protein 4 | chr4 | GO:0008234 | Not Cancer Driver | No | 148 | 0.133 | 788 | 120 | 0.152 | 0 |
| OTUD5 | OTUD5 | Q96G74 | OTU domain-containing protein 5 | chrX | GO:0008234 | Not Cancer Driver | No | 55 | 0.096 | 430 | 39 | 0.091 | 4 |
| OTUD7B | OTUD7B | Q6GQQ9 | OTU domain-containing protein 7B | chr1 | GO:0008234 | Not Cancer Driver | No | 124 | 0.147 | 537 | 87 | 0.162 | 0 |
| OTULIN | OTULIN | Q96BN8 | Ubiquitin thioesterase otulin | chr5 | GO:0008234 | Not Cancer Driver | No | 47 | 0.134 | 97 | 5 | 0.052 | 2 |
| PGPEP1 | PGPEP1 | Q9NXJ5 | Pyroglutamyl-peptidase 1 | chr19 | GO:0008234 | Not Cancer Driver | No | 22 | 0.105 | 0 | 0 | 0.0 | 0 |
| PGPEP1L | PGPEP1L | A6NFU8 | Pyroglutamyl-peptidase 1-like protein | chr15 | GO:0008234 | Not Cancer Driver | No | 36 | 0.184 | 20 | 2 | 0.1 | 0 |
| PIGK | PIGK | Q92643 | GPI-anchor transamidase | chr1 | GO:0008234 | Not Cancer Driver | No | 54 | 0.137 | 37 | 9 | 0.243 | 5 |
| PRPF8 | PRPF8 | Q6P2Q9 | Pre-mRNA-processing-splicing factor 8 | chr17 | GO:0008234 | Not Cancer Driver | No | 255 | 0.109 | 225 | 26 | 0.116 | 8 |
| PSMD14 | PSMD14 | O00487 | 26S proteasome non-ATPase regulatory subunit 14 | chr2 | GO:0008234 | Not Cancer Driver | No | 23 | 0.074 | 67 | 6 | 0.09 | 0 |
| PSMD7 | PSMD7 | P51665 | 26S proteasome non-ATPase regulatory subunit 7 | chr16 | GO:0008234 | Not Cancer Driver | No | 39 | 0.12 | 70 | 4 | 0.057 | 0 |
| SCRN1_ENST00000242059 | SCRN1 | Q12765 | Secernin-1 | chr7 | GO:0008234 | Not Cancer Driver | No | 73 | 0.176 | 112 | 21 | 0.188 | 0 |
| SCRN2 | SCRN2 | Q96FV2 | Secernin-2 | chr17 | GO:0008234 | Not Cancer Driver | No | 65 | 0.153 | 145 | 24 | 0.166 | 0 |
| SCRN3 | SCRN3 | Q0VDG4 | Secernin-3 | chr2 | GO:0008234 | Not Cancer Driver | No | 55 | 0.13 | 42 | 3 | 0.071 | 0 |
| SENP1 | SENP1 | Q9P0U3 | Sentrin-specific protease 1 | chr12 | GO:0008234 | Not Cancer Driver | No | 64 | 0.099 | 355 | 44 | 0.124 | 0 |
| SENP2 | SENP2 | Q9HC62 | Sentrin-specific protease 2 | chr3 | GO:0008234 | Not Cancer Driver | No | 73 | 0.124 | 285 | 38 | 0.133 | 0 |
| SENP3_ENST00000429205 | SENP3 | Q9H4L4 | Sentrin-specific protease 3 | chr17 | GO:0008234 | Not Cancer Driver | No | 53 | 0.092 | 288 | 30 | 0.104 | 0 |
| SENP5 | SENP5 | Q96HI0 | Sentrin-specific protease 5 | chr3 | GO:0008234 | Not Cancer Driver | No | 85 | 0.113 | 293 | 34 | 0.116 | 0 |
| SENP6 | SENP6 | Q9GZR1 | Sentrin-specific protease 6 | chr6 | GO:0008234 | Not Cancer Driver | No | 120 | 0.108 | 612 | 59 | 0.096 | 0 |
| SENP7 | SENP7 | Q9BQF6 | Sentrin-specific protease 7 | chr3 | GO:0008234 | Not Cancer Driver | No | 149 | 0.142 | 523 | 73 | 0.14 | 0 |
| SENP8 | SENP8 | Q96LD8 | Sentrin-specific protease 8 | chr15 | GO:0008234 | Not Cancer Driver | No | 16 | 0.075 | 0 | 0 | 0.0 | 0 |
| STAMBPL1_ENST00000371924 | STAMBPL1 | Q96FJ0 | AMSH-like protease | chr10 | GO:0008234 | Not Cancer Driver | No | 48 | 0.11 | 70 | 7 | 0.1 | 0 |
| STAMBP_ENST00000339566 | STAMBP | O95630 | STAM-binding protein | chr2 | GO:0008234 | Not Cancer Driver | No | 51 | 0.12 | 139 | 16 | 0.115 | 6 |
| TINAGL1 | TINAGL1 | Q9GZM7 | Tubulointerstitial nephritis antigen-like | chr1 | GO:0008234 | Not Cancer Driver | No | 62 | 0.133 | 89 | 15 | 0.169 | 0 |
| TNFAIP3 | TNFAIP3 | P21580 | Tumor necrosis factor alpha-induced protein 3 | chr6 | GO:0008234 | Census, Compendium | Yes | 98 | 0.124 | 231 | 33 | 0.143 | 1 |
| UCHL3 | UCHL3 | P15374 | Ubiquitin carboxyl-terminal hydrolase isozyme L3 | chr13 | GO:0008234 | Not Cancer Driver | No | 26 | 0.113 | 61 | 3 | 0.049 | 0 |
| UFSP2 | UFSP2 | Q9NUQ7 | Ufm1-specific protease 2 | chr4 | GO:0008234 | Not Cancer Driver | No | 53 | 0.113 | 22 | 3 | 0.136 | 2 |
| USP13 | USP13 | Q92995 | Ubiquitin carboxyl-terminal hydrolase 13 | chr3 | GO:0008234 | Not Cancer Driver | No | 121 | 0.14 | 224 | 42 | 0.188 | 0 |
| USP15 | USP15 | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | chr12 | GO:0008234 | Not Cancer Driver | No | 136 | 0.139 | 259 | 39 | 0.151 | 0 |
| USP18 | USP18 | Q9UMW8 | Ubl carboxyl-terminal hydrolase 18 | chr22 | GO:0008234 | Not Cancer Driver | No | 34 | 0.091 | 29 | 8 | 0.276 | 0 |
| USP19_ENST00000398888 | USP19 | O94966 | Ubiquitin carboxyl-terminal hydrolase 19 | chr3 | GO:0008234 | Not Cancer Driver | No | 161 | 0.122 | 539 | 68 | 0.126 | 0 |
| USP21_ENST00000289865 | USP21 | Q9UK80 | Ubiquitin carboxyl-terminal hydrolase 21 | chr1 | GO:0008234 | Not Cancer Driver | No | 95 | 0.168 | 230 | 47 | 0.204 | 0 |
| USP27X | USP27X | A6NNY8 | Ubiquitin carboxyl-terminal hydrolase 27 | chrX | GO:0008234 | Not Cancer Driver | No | 31 | 0.071 | 69 | 3 | 0.043 | 1 |
| USP43 | USP43 | Q70EL4 | Ubiquitin carboxyl-terminal hydrolase 43 | chr17 | GO:0008234 | Not Cancer Driver | No | 134 | 0.119 | 562 | 56 | 0.1 | 0 |
| USP7 | USP7 | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | chr16 | GO:0008234 | Not Cancer Driver | No | 170 | 0.154 | 215 | 45 | 0.209 | 0 |
| USP9X_ENST00000378308 | USP9X | Q93008 | Probable ubiquitin carboxyl-terminal hydrolase FAF-X | chrX | GO:0008234 | Census, Compendium | Yes | 339 | 0.133 | 405 | 51 | 0.126 | 1 |
| USP9Y | USP9Y | O00507 | Probable ubiquitin carboxyl-terminal hydrolase FAF-Y | chrY | GO:0008234 | Not Cancer Driver | No | 83 | 0.032 | 349 | 6 | 0.017 | 0 |
| USPL1 | USPL1 | Q5W0Q7 | SUMO-specific isopeptidase USPL1 | chr13 | GO:0008234 | Not Cancer Driver | No | 107 | 0.098 | 578 | 55 | 0.095 | 0 |
| YOD1 | YOD1 | Q5VVQ6 | Ubiquitin thioesterase OTU1 | chr1 | GO:0008234 | Not Cancer Driver | No | 30 | 0.086 | 120 | 6 | 0.05 | 0 |