Total number of protein in "GO:0008219" GO term: 209
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0008219 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| AC069368.1 | AC069368.1 | C9J4A7 | PH domain-containing protein (Fragment) | chr15 | GO:0008219 | Not Cancer Driver | No | 26 | 0.115 | 62 | 10 | 0.161 | 0 |
| ADARB1 | ADARB1 | P78563 | Double-stranded RNA-specific editase 1 | chr21 | GO:0008219 | Not Cancer Driver | No | 102 | 0.138 | 348 | 34 | 0.098 | 1 |
| AIM2 | AIM2 | O14862 | Interferon-inducible protein AIM2 | chr1 | GO:0008219 | Not Cancer Driver | No | 73 | 0.213 | 78 | 22 | 0.282 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0008219 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| AKT2 | AKT2 | P31751 | RAC-beta serine/threonine-protein kinase | chr19 | GO:0008219 | Census | Yes | 77 | 0.16 | 84 | 9 | 0.107 | 2 |
| ALS2 | ALS2 | Q96Q42 | Alsin | chr2 | GO:0008219 | Not Cancer Driver | No | 194 | 0.117 | 353 | 36 | 0.102 | 0 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0008219 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| APIP | APIP | Q96GX9 | Methylthioribulose-1-phosphate dehydratase | chr11 | GO:0008219 | Not Cancer Driver | No | 24 | 0.099 | 26 | 1 | 0.038 | 0 |
| ARF6 | ARF6 | P62330 | ADP-ribosylation factor 6 | chr14 | GO:0008219 | Not Cancer Driver | No | 18 | 0.103 | 5 | 0 | 0.0 | 0 |
| ARL6IP5 | ARL6IP5 | O75915 | PRA1 family protein 3 | chr3 | GO:0008219 | Not Cancer Driver | No | 26 | 0.138 | 0 | 0 | 0.0 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0008219 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| AXIN2 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | GO:0008219 | Census, Compendium | Yes | 114 | 0.135 | 547 | 77 | 0.141 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0008219 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0008219 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BCL10 | BCL10 | O95999 | B-cell lymphoma/leukemia 10 | chr1 | GO:0008219 | Census, Compendium | Yes | 36 | 0.155 | 151 | 25 | 0.166 | 0 |
| BCL2L1 | BCL2L1 | Q07817 | Bcl-2-like protein 1 | chr20 | GO:0008219 | Not Cancer Driver | No | 29 | 0.124 | 55 | 3 | 0.055 | 0 |
| BCL2L11 | BCL2L11 | O43521 | Bcl-2-like protein 11 | chr2 | GO:0008219 | Not Cancer Driver | No | 42 | 0.212 | 130 | 17 | 0.131 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0008219 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BIRC2 | BIRC2 | Q13490 | Baculoviral IAP repeat-containing protein 2 | chr11 | GO:0008219 | Not Cancer Driver | No | 69 | 0.112 | 83 | 9 | 0.108 | 0 |
| BMF_ENST00000561360 | BMF | Q96LC9 | Bcl-2-modifying factor | chr15 | GO:0008219 | Not Cancer Driver | No | 22 | 0.12 | 94 | 9 | 0.096 | 0 |
| BMP4 | BMP4 | P12644 | Bone morphogenetic protein 4 | chr14 | GO:0008219 | Not Cancer Driver | No | 86 | 0.211 | 142 | 26 | 0.183 | 5 |
| BMPR2 | BMPR2 | Q13873 | Bone morphogenetic protein receptor type-2 | chr2 | GO:0008219 | Compendium | Yes | 141 | 0.136 | 601 | 70 | 0.116 | 19 |
| BRINP1 | BRINP1 | O60477 | BMP/retinoic acid-inducible neural-specific protein 1 | chr9 | GO:0008219 | Not Cancer Driver | No | 273 | 0.359 | 36 | 17 | 0.472 | 0 |
| CACNA1A_ENST00000360228 | CACNA1A | O00555 | Voltage-dependent P/Q-type calcium channel subunit alpha-1A | chr19 | GO:0008219 | Not Cancer Driver | No | 436 | 0.174 | 1144 | 132 | 0.115 | 46 |
| CAPN10 | CAPN10 | Q9HC96 | Calpain-10 | chr2 | GO:0008219 | Not Cancer Driver | No | 87 | 0.129 | 52 | 6 | 0.115 | 0 |
| CASP1 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0008219 | Not Cancer Driver | No | 79 | 0.196 | 87 | 18 | 0.207 | 0 |
| CASP14 | CASP14 | P31944 | Caspase-14 | chr19 | GO:0008219 | Not Cancer Driver | No | 50 | 0.207 | 84 | 13 | 0.155 | 0 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0008219 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0008219 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CASP4 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0008219 | Not Cancer Driver | No | 56 | 0.149 | 102 | 14 | 0.137 | 0 |
| CASP6 | CASP6 | P55212 | Caspase-6 | chr4 | GO:0008219 | Not Cancer Driver | No | 28 | 0.096 | 24 | 4 | 0.167 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0008219 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0008219 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CCN1 | CCN1 | O00622 | CCN family member 1 | chr1 | GO:0008219 | Not Cancer Driver | No | 33 | 0.087 | 12 | 0 | 0.0 | 0 |
| CDKN1B | CDKN1B | P46527 | Cyclin-dependent kinase inhibitor 1B | chr12 | GO:0008219 | Census, Compendium | Yes | 19 | 0.096 | 198 | 19 | 0.096 | 0 |
| CDKN2D_ENST00000335766 | CDKN2D | P55273 | Cyclin-dependent kinase 4 inhibitor D | chr19 | GO:0008219 | Not Cancer Driver | No | 17 | 0.102 | 44 | 3 | 0.068 | 0 |
| CERS3 | CERS3 | Q8IU89 | Ceramide synthase 3 | chr15 | GO:0008219 | Not Cancer Driver | No | 90 | 0.235 | 21 | 10 | 0.476 | 0 |
| CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0008219 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
| CIDEA | CIDEA | O60543 | Cell death activator CIDE-A | chr18 | GO:0008219 | Not Cancer Driver | No | 43 | 0.196 | 32 | 3 | 0.094 | 0 |
| CLC | CLC | Q05315 | Galectin-10 | chr19 | GO:0008219 | Not Cancer Driver | No | 29 | 0.204 | 0 | 0 | 0.0 | 0 |
| COL4A3 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0008219 | Not Cancer Driver | No | 310 | 0.186 | 1433 | 277 | 0.193 | 13 |
| CRKL | CRKL | P46109 | Crk-like protein | chr22 | GO:0008219 | Not Cancer Driver | No | 38 | 0.125 | 160 | 25 | 0.156 | 0 |
| CRYAB_ENST00000616970 | CRYAB | P02511 | Alpha-crystallin B chain | chr11 | GO:0008219 | Not Cancer Driver | No | 22 | 0.126 | 59 | 11 | 0.186 | 4 |
| CTSL | CTSL | P07711 | Procathepsin L | chr9 | GO:0008219 | Not Cancer Driver | No | 47 | 0.141 | 34 | 4 | 0.118 | 0 |
| CUL3 | CUL3 | Q13618 | Cullin-3 | chr2 | GO:0008219 | Census, Compendium | Yes | 123 | 0.16 | 167 | 23 | 0.138 | 3 |
| CYLD | CYLD | Q9NQC7 | Ubiquitin carboxyl-terminal hydrolase CYLD | chr16 | GO:0008219 | Census, Compendium | Yes | 116 | 0.121 | 213 | 31 | 0.146 | 3 |
| CYP26B1 | CYP26B1 | Q9NR63 | Cytochrome P450 26B1 | chr2 | GO:0008219 | Not Cancer Driver | No | 113 | 0.221 | 10 | 3 | 0.3 | 2 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0008219 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DAPK2 | DAPK2 | Q9UIK4 | Death-associated protein kinase 2 | chr15 | GO:0008219 | Not Cancer Driver | No | 55 | 0.149 | 53 | 9 | 0.17 | 0 |
| DFFA | DFFA | O00273 | DNA fragmentation factor subunit alpha | chr1 | GO:0008219 | Not Cancer Driver | No | 47 | 0.142 | 113 | 18 | 0.159 | 0 |
| DHX9 | DHX9 | Q08211 | ATP-dependent RNA helicase A | chr1 | GO:0008219 | Compendium | Yes | 182 | 0.143 | 331 | 42 | 0.127 | 0 |
| DIO3 | DIO3 | P55073 | Thyroxine 5-deiodinase | chr14 | GO:0008219 | Not Cancer Driver | No | 88 | 0.289 | 71 | 18 | 0.254 | 0 |
| DMPK_ENST00000291270 | DMPK | Q09013 | Myotonin-protein kinase | chr19 | GO:0008219 | Not Cancer Driver | No | 54 | 0.086 | 220 | 14 | 0.064 | 0 |
| DNAJA3 | DNAJA3 | Q96EY1 | DnaJ homolog subfamily A member 3, mitochondrial | chr16 | GO:0008219 | Not Cancer Driver | No | 50 | 0.104 | 152 | 21 | 0.138 | 0 |
| DNASE1L3 | DNASE1L3 | Q13609 | Deoxyribonuclease gamma | chr3 | GO:0008219 | Not Cancer Driver | No | 43 | 0.141 | 15 | 4 | 0.267 | 0 |
| DNM1L_ENST00000549701 | DNM1L | O00429 | Dynamin-1-like protein | chr12 | GO:0008219 | Not Cancer Driver | No | 67 | 0.091 | 212 | 23 | 0.108 | 7 |
| DNMT3A | DNMT3A | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | chr2 | GO:0008219 | Census, Compendium | Yes | 194 | 0.213 | 371 | 59 | 0.159 | 16 |
| E2F1 | E2F1 | Q01094 | Transcription factor E2F1 | chr20 | GO:0008219 | Not Cancer Driver | No | 49 | 0.112 | 272 | 23 | 0.085 | 0 |
| E2F2 | E2F2 | Q14209 | Transcription factor E2F2 | chr1 | GO:0008219 | Not Cancer Driver | No | 42 | 0.096 | 282 | 28 | 0.099 | 0 |
| EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0008219 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
| EIF4G2_ENST00000640650 | EIF4G2 | P78344 | Eukaryotic translation initiation factor 4 gamma 2 | chr11 | GO:0008219 | Not Cancer Driver | No | 104 | 0.115 | 382 | 43 | 0.113 | 0 |
| ELANE_ENST00000263621 | ELANE | P08246 | Neutrophil elastase | chr19 | GO:0008219 | Not Cancer Driver | No | 39 | 0.146 | 18 | 3 | 0.167 | 89 |
| EMP1 | EMP1 | P54849 | Epithelial membrane protein 1 | chr12 | GO:0008219 | Not Cancer Driver | No | 18 | 0.115 | 0 | 0 | 0.0 | 0 |
| EMP2_ENST00000536829 | EMP2 | P54851 | Epithelial membrane protein 2 | chr16 | GO:0008219 | Not Cancer Driver | No | 24 | 0.144 | 0 | 0 | 0.0 | 2 |
| EMP3_ENST00000597279 | EMP3 | P54852 | Epithelial membrane protein 3 | chr19 | GO:0008219 | Not Cancer Driver | No | 18 | 0.11 | 0 | 0 | 0.0 | 0 |
| ENDOG | ENDOG | Q14249 | Endonuclease G, mitochondrial | chr9 | GO:0008219 | Not Cancer Driver | No | 11 | 0.037 | 61 | 1 | 0.016 | 0 |
| ETV6 | ETV6 | P41212 | Transcription factor ETV6 | chr12 | GO:0008219 | Census, Compendium | Yes | 98 | 0.217 | 251 | 46 | 0.183 | 3 |
| EXOC5 | EXOC5 | O00471 | Exocyst complex component 5 | chr14 | GO:0008219 | Not Cancer Driver | No | 59 | 0.083 | 57 | 4 | 0.07 | 0 |
| FADD | FADD | Q13158 | FAS-associated death domain protein | chr11 | GO:0008219 | Not Cancer Driver | No | 26 | 0.125 | 45 | 10 | 0.222 | 1 |
| FAF1 | FAF1 | Q9UNN5 | FAS-associated factor 1 | chr1 | GO:0008219 | Not Cancer Driver | No | 83 | 0.128 | 241 | 34 | 0.141 | 0 |
| FAP | FAP | Q12884 | Prolyl endopeptidase FAP | chr2 | GO:0008219 | Not Cancer Driver | No | 158 | 0.208 | 6 | 2 | 0.333 | 0 |
| FAS | FAS | P25445 | Tumor necrosis factor receptor superfamily member 6 | chr10 | GO:0008219 | Census, Compendium | Yes | 55 | 0.164 | 62 | 18 | 0.29 | 22 |
| FASLG | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0008219 | Not Cancer Driver | No | 65 | 0.231 | 94 | 18 | 0.191 | 1 |
| FBH1_ENST00000362091 | FBH1 | Q8NFZ0 | F-box DNA helicase 1 | chr10 | GO:0008219 | Not Cancer Driver | No | 139 | 0.133 | 192 | 32 | 0.167 | 0 |
| FGF21 | FGF21 | Q9NSA1 | Fibroblast growth factor 21 | chr19 | GO:0008219 | Not Cancer Driver | No | 37 | 0.177 | 109 | 24 | 0.22 | 0 |
| FGF4 | FGF4 | P08620 | Fibroblast growth factor 4 | chr11 | GO:0008219 | Not Cancer Driver | No | 16 | 0.078 | 21 | 3 | 0.143 | 0 |
| FOSL2 | FOSL2 | P15408 | Fos-related antigen 2 | chr2 | GO:0008219 | Not Cancer Driver | No | 54 | 0.166 | 323 | 54 | 0.167 | 0 |
| FZD5 | FZD5 | Q13467 | Frizzled-5 | chr2 | GO:0008219 | Not Cancer Driver | No | 45 | 0.077 | 58 | 4 | 0.069 | 0 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0008219 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| GDF6 | GDF6 | Q6KF10 | Growth/differentiation factor 6 | chr8 | GO:0008219 | Not Cancer Driver | No | 91 | 0.2 | 225 | 46 | 0.204 | 14 |
| GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0008219 | Not Cancer Driver | No | 385 | 0.244 | 1352 | 327 | 0.242 | 7 |
| GNGT1_ENST00000429473 | GNGT1 | P63211 | Guanine nucleotide-binding protein G(T) subunit gamma-T1 | chr7 | GO:0008219 | Not Cancer Driver | No | 14 | 0.189 | 25 | 4 | 0.16 | 0 |
| GSDMA | GSDMA | Q96QA5 | Gasdermin-A | chr17 | GO:0008219 | Not Cancer Driver | No | 67 | 0.151 | 87 | 15 | 0.172 | 0 |
| GSDMB | GSDMB | Q8TAX9 | Gasdermin-B | chr17 | GO:0008219 | Not Cancer Driver | No | 50 | 0.12 | 84 | 11 | 0.131 | 0 |
| GSDMC | GSDMC | Q9BYG8 | Gasdermin-C | chr8 | GO:0008219 | Not Cancer Driver | No | 125 | 0.246 | 0 | 0 | 0.0 | 0 |
| GSDMD_ENST00000262580 | GSDMD | P57764 | Gasdermin-D | chr8 | GO:0008219 | Not Cancer Driver | No | 47 | 0.097 | 156 | 16 | 0.103 | 0 |
| GSDME_ENST00000409775 | GSDME | O60443 | Gasdermin-E | chr7 | GO:0008219 | Not Cancer Driver | No | 81 | 0.163 | 14 | 3 | 0.214 | 0 |
| GSN | GSN | P06396 | Gelsolin | chr9 | GO:0008219 | Not Cancer Driver | No | 76 | 0.097 | 316 | 28 | 0.089 | 2 |
| GZMA | GZMA | P12544 | Granzyme A | chr5 | GO:0008219 | Not Cancer Driver | No | 70 | 0.267 | 5 | 1 | 0.2 | 0 |
| GZMB | GZMB | P10144 | Granzyme B | chr14 | GO:0008219 | Not Cancer Driver | No | 49 | 0.198 | 103 | 23 | 0.223 | 0 |
| GZMM | GZMM | P51124 | Granzyme M | chr19 | GO:0008219 | Not Cancer Driver | No | 25 | 0.097 | 12 | 1 | 0.083 | 0 |
| HAND2 | HAND2 | P61296 | Heart- and neural crest derivatives-expressed protein 2 | chr4 | GO:0008219 | Not Cancer Driver | No | 47 | 0.217 | 124 | 29 | 0.234 | 0 |
| HCAR2 | HCAR2 | Q8TDS4 | Hydroxycarboxylic acid receptor 2 | chr12 | GO:0008219 | Not Cancer Driver | No | 78 | 0.215 | 43 | 8 | 0.186 | 0 |
| HIPK1_ENST00000426820 | HIPK1 | Q86Z02 | Homeodomain-interacting protein kinase 1 | chr1 | GO:0008219 | Not Cancer Driver | No | 158 | 0.131 | 565 | 89 | 0.158 | 0 |
| HMOX1 | HMOX1 | P09601 | Heme oxygenase 1 | chr22 | GO:0008219 | Not Cancer Driver | No | 46 | 0.16 | 81 | 13 | 0.16 | 0 |
| HTR2A | HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | chr13 | GO:0008219 | Not Cancer Driver | No | 105 | 0.223 | 44 | 8 | 0.182 | 0 |
| IKBKG_ENST00000611071 | IKBKG | Q9Y6K9 | NF-kappa-B essential modulator | chrX | GO:0008219 | Not Cancer Driver | No | 6 | 0.014 | 301 | 6 | 0.02 | 22 |
| IL10 | IL10 | P22301 | Interleukin-10 | chr1 | GO:0008219 | Not Cancer Driver | No | 19 | 0.107 | 23 | 1 | 0.043 | 0 |
| IL17A | IL17A | Q16552 | Interleukin-17A | chr6 | GO:0008219 | Not Cancer Driver | No | 52 | 0.335 | 56 | 21 | 0.375 | 0 |
| IL1A | IL1A | P01583 | Interleukin-1 alpha | chr2 | GO:0008219 | Not Cancer Driver | No | 30 | 0.111 | 35 | 6 | 0.171 | 0 |
| IL1B | IL1B | P01584 | Interleukin-1 beta | chr2 | GO:0008219 | Not Cancer Driver | No | 39 | 0.145 | 16 | 3 | 0.188 | 0 |
| IL2RA | IL2RA | P01589 | Interleukin-2 receptor subunit alpha | chr10 | GO:0008219 | Not Cancer Driver | No | 51 | 0.188 | 131 | 29 | 0.221 | 2 |
| IL6 | IL6 | P05231 | Interleukin-6 | chr7 | GO:0008219 | Not Cancer Driver | No | 35 | 0.165 | 58 | 7 | 0.121 | 0 |
| IPMK | IPMK | Q8NFU5 | Inositol polyphosphate multikinase | chr10 | GO:0008219 | Not Cancer Driver | No | 50 | 0.12 | 108 | 9 | 0.083 | 0 |
| IRF3_ENST00000597198 | IRF3 | Q14653 | Interferon regulatory factor 3 | chr19 | GO:0008219 | Not Cancer Driver | No | 36 | 0.084 | 204 | 21 | 0.103 | 1 |
| ITPK1 | ITPK1 | Q13572 | Inositol-tetrakisphosphate 1-kinase | chr14 | GO:0008219 | Not Cancer Driver | No | 74 | 0.179 | 24 | 1 | 0.042 | 0 |
| JAG2 | JAG2 | Q9Y219 | Protein jagged-2 | chr14 | GO:0008219 | Not Cancer Driver | No | 126 | 0.102 | 158 | 24 | 0.152 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0008219 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| KDELR1 | KDELR1 | P24390 | ER lumen protein-retaining receptor 1 | chr19 | GO:0008219 | Not Cancer Driver | No | 32 | 0.151 | 0 | 0 | 0.0 | 0 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0008219 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| KITLG | KITLG | P21583 | Kit ligand | chr12 | GO:0008219 | Not Cancer Driver | No | 48 | 0.176 | 61 | 9 | 0.148 | 1 |
| KLK5_ENST00000593428 | KLK5 | Q9Y337 | Kallikrein-5 | chr19 | GO:0008219 | Not Cancer Driver | No | 69 | 0.235 | 75 | 16 | 0.213 | 0 |
| KLK8_ENST00000600767 | KLK8 | O60259 | Kallikrein-8 | chr19 | GO:0008219 | Not Cancer Driver | No | 65 | 0.25 | 76 | 15 | 0.197 | 0 |
| KRT18_ENST00000388837 | KRT18 | P05783 | Keratin, type I cytoskeletal 18 | chr12 | GO:0008219 | Not Cancer Driver | No | 57 | 0.133 | 179 | 21 | 0.117 | 4 |
| LEF1 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0008219 | Census | Yes | 64 | 0.16 | 370 | 57 | 0.154 | 0 |
| LIPK | LIPK | Q5VXJ0 | Lipase member K | chr10 | GO:0008219 | Not Cancer Driver | No | 44 | 0.11 | 0 | 0 | 0.0 | 0 |
| LIPM | LIPM | Q5VYY2 | Lipase member M | chr10 | GO:0008219 | Not Cancer Driver | No | 18 | 0.043 | 13 | 0 | 0.0 | 0 |
| LIPN | LIPN | Q5VXI9 | Lipase member N | chr10 | GO:0008219 | Not Cancer Driver | No | 53 | 0.133 | 8 | 1 | 0.125 | 0 |
| LMBR1L | LMBR1L | Q6UX01 | Protein LMBR1L | chr12 | GO:0008219 | Not Cancer Driver | No | 57 | 0.117 | 4 | 0 | 0.0 | 0 |
| LRP5 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0008219 | Not Cancer Driver | No | 253 | 0.157 | 188 | 28 | 0.149 | 55 |
| MAP3K11 | MAP3K11 | Q16584 | Mitogen-activated protein kinase kinase kinase 11 | chr11 | GO:0008219 | Not Cancer Driver | No | 97 | 0.115 | 466 | 54 | 0.116 | 0 |
| MAP3K20 | MAP3K20 | Q9NYL2 | Mitogen-activated protein kinase kinase kinase 20 | chr2 | GO:0008219 | Not Cancer Driver | No | 101 | 0.126 | 294 | 41 | 0.139 | 1 |
| MAP3K5 | MAP3K5 | Q99683 | Mitogen-activated protein kinase kinase kinase 5 | chr6 | GO:0008219 | Not Cancer Driver | No | 197 | 0.143 | 242 | 29 | 0.12 | 0 |
| MAP3K7 | MAP3K7 | O43318 | Mitogen-activated protein kinase kinase kinase 7 | chr6 | GO:0008219 | Not Cancer Driver | No | 104 | 0.172 | 333 | 66 | 0.198 | 6 |
| MEGF10_ENST00000503335 | MEGF10 | Q96KG7 | Multiple epidermal growth factor-like domains protein 10 | chr5 | GO:0008219 | Not Cancer Driver | No | 216 | 0.189 | 204 | 42 | 0.206 | 2 |
| MLKL | MLKL | Q8NB16 | Mixed lineage kinase domain-like protein | chr16 | GO:0008219 | Not Cancer Driver | No | 56 | 0.119 | 89 | 15 | 0.169 | 0 |
| MTOR | MTOR | P42345 | Serine/threonine-protein kinase mTOR | chr1 | GO:0008219 | Census, Compendium | Yes | 379 | 0.149 | 296 | 37 | 0.125 | 18 |
| MYC_ENST00000377970 | MYC | P01106 | Myc proto-oncogene protein | chr8 | GO:0008219 | Census, Compendium | Yes | 80 | 0.182 | 299 | 46 | 0.154 | 0 |
| NAIP_ENST00000194097 | NAIP | Q13075 | Baculoviral IAP repeat-containing protein 1 | chr5 | GO:0008219 | Not Cancer Driver | No | 39 | 0.028 | 67 | 4 | 0.06 | 0 |
| NDOR1_ENST00000344894 | NDOR1 | Q9UHB4 | NADPH-dependent diflavin oxidoreductase 1 | chr9 | GO:0008219 | Not Cancer Driver | No | 60 | 0.101 | 67 | 7 | 0.104 | 0 |
| NINJ1 | NINJ1 | Q92982 | Ninjurin-1 | chr9 | GO:0008219 | Not Cancer Driver | No | 17 | 0.112 | 29 | 0 | 0.0 | 0 |
| NKX2-5 | NKX2-5 | P52952 | Homeobox protein Nkx-2.5 | chr5 | GO:0008219 | Not Cancer Driver | No | 48 | 0.148 | 181 | 22 | 0.122 | 55 |
| NLRC4_ENST00000360906 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0008219 | Not Cancer Driver | No | 205 | 0.2 | 15 | 2 | 0.133 | 3 |
| NLRP1_ENST00000572272 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0008219 | Not Cancer Driver | No | 222 | 0.151 | 340 | 65 | 0.191 | 6 |
| NLRP6 | NLRP6 | P59044 | NACHT, LRR and PYD domains-containing protein 6 | chr11 | GO:0008219 | Not Cancer Driver | No | 106 | 0.119 | 203 | 28 | 0.138 | 0 |
| NLRP9 | NLRP9 | Q7RTR0 | NACHT, LRR and PYD domains-containing protein 9 | chr19 | GO:0008219 | Not Cancer Driver | No | 247 | 0.249 | 0 | 0 | 0.0 | 0 |
| NOL3_ENST00000268605 | NOL3 | O60936 | Nucleolar protein 3 | chr16 | GO:0008219 | Not Cancer Driver | No | 20 | 0.096 | 179 | 17 | 0.095 | 2 |
| NOTCH1 | NOTCH1 | P46531 | Neurogenic locus notch homolog protein 1 | chr9 | GO:0008219 | Census, Compendium | Yes | 363 | 0.142 | 686 | 87 | 0.127 | 3 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0008219 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
| NUP62 | NUP62 | P37198 | Nuclear pore glycoprotein p62 | chr19 | GO:0008219 | Not Cancer Driver | No | 76 | 0.146 | 377 | 56 | 0.149 | 1 |
| OLR1 | OLR1 | P78380 | Oxidized low-density lipoprotein receptor 1 | chr12 | GO:0008219 | Not Cancer Driver | No | 38 | 0.139 | 75 | 8 | 0.107 | 0 |
| OPTN_ENST00000263036 | OPTN | Q96CV9 | Optineurin | chr10 | GO:0008219 | Not Cancer Driver | No | 58 | 0.101 | 470 | 51 | 0.109 | 6 |
| PARP4 | PARP4 | Q9UKK3 | Protein mono-ADP-ribosyltransferase PARP4 | chr13 | GO:0008219 | Compendium | Yes | 218 | 0.126 | 325 | 40 | 0.123 | 0 |
| PDE6B | PDE6B | P35913 | Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta | chr4 | GO:0008219 | Not Cancer Driver | No | 144 | 0.169 | 44 | 9 | 0.205 | 13 |
| PGAM5 | PGAM5 | Q96HS1 | Serine/threonine-protein phosphatase PGAM5, mitochondrial | chr12 | GO:0008219 | Not Cancer Driver | No | 32 | 0.111 | 102 | 12 | 0.118 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0008219 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3CG | PIK3CG | P48736 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | chr7 | GO:0008219 | Not Cancer Driver | No | 318 | 0.289 | 121 | 39 | 0.322 | 0 |
| PJVK_ENST00000644580 | PJVK | Q0ZLH3 | Pejvakin | chr2 | GO:0008219 | Not Cancer Driver | No | 48 | 0.136 | 1 | 0 | 0.0 | 3 |
| PKN1_ENST00000242783 | PKN1 | Q16512 | Serine/threonine-protein kinase N1 | chr19 | GO:0008219 | Not Cancer Driver | No | 120 | 0.127 | 459 | 54 | 0.118 | 0 |
| PLEKHO2 | PLEKHO2 | Q8TD55 | Pleckstrin homology domain-containing family O member 2 | chr15 | GO:0008219 | Not Cancer Driver | No | 61 | 0.124 | 402 | 56 | 0.139 | 0 |
| PMP22_ENST00000612492 | PMP22 | Q01453 | Peripheral myelin protein 22 | chr17 | GO:0008219 | Not Cancer Driver | No | 20 | 0.125 | 0 | 0 | 0.0 | 37 |
| PNPLA8 | PNPLA8 | Q9NP80 | Calcium-independent phospholipase A2-gamma | chr7 | GO:0008219 | Not Cancer Driver | No | 94 | 0.12 | 140 | 18 | 0.129 | 0 |
| PPIF | PPIF | P30405 | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | chr10 | GO:0008219 | Not Cancer Driver | No | 19 | 0.092 | 43 | 4 | 0.093 | 0 |
| PPP2R1B_ENST00000527614 | PPP2R1B | P30154 | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform | chr11 | GO:0008219 | Not Cancer Driver | No | 72 | 0.12 | 17 | 1 | 0.059 | 0 |
| PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0008219 | Compendium | Yes | 118 | 0.134 | 246 | 34 | 0.138 | 0 |
| PRKDC | PRKDC | P78527 | DNA-dependent protein kinase catalytic subunit | chr8 | GO:0008219 | Not Cancer Driver | No | 538 | 0.13 | 421 | 61 | 0.145 | 2 |
| PTGER3_ENST00000370931 | PTGER3 | P43115 | Prostaglandin E2 receptor EP3 subtype | chr1 | GO:0008219 | Not Cancer Driver | No | 79 | 0.203 | 17 | 2 | 0.118 | 0 |
| PYGL | PYGL | P06737 | Glycogen phosphorylase, liver form | chr14 | GO:0008219 | Not Cancer Driver | No | 98 | 0.116 | 23 | 2 | 0.087 | 2 |
| RB1 | RB1 | P06400 | Retinoblastoma-associated protein | chr13 | GO:0008219 | Census, Compendium | Yes | 140 | 0.151 | 282 | 32 | 0.113 | 22 |
| RIPK1_ENST00000380409 | RIPK1 | Q13546 | Receptor-interacting serine/threonine-protein kinase 1 | chr6 | GO:0008219 | Compendium | Yes | 82 | 0.122 | 277 | 39 | 0.141 | 4 |
| RIPK3 | RIPK3 | Q9Y572 | Receptor-interacting serine/threonine-protein kinase 3 | chr14 | GO:0008219 | Not Cancer Driver | No | 66 | 0.127 | 295 | 39 | 0.132 | 0 |
| RNF112 | RNF112 | Q9ULX5 | RING finger protein 112 | chr17 | GO:0008219 | Not Cancer Driver | No | 86 | 0.136 | 168 | 26 | 0.155 | 0 |
| ROBO2_ENST00000461745 | ROBO2 | Q9HCK4 | Roundabout homolog 2 | chr3 | GO:0008219 | Census | Yes | 407 | 0.295 | 874 | 259 | 0.296 | 2 |
| RPS6 | RPS6 | P62753 | 40S ribosomal protein S6 | chr9 | GO:0008219 | Not Cancer Driver | No | 38 | 0.153 | 150 | 25 | 0.167 | 0 |
| RPS6KA2_ENST00000265678 | RPS6KA2 | Q15349 | Ribosomal protein S6 kinase alpha-2 | chr6 | GO:0008219 | Not Cancer Driver | No | 133 | 0.181 | 91 | 15 | 0.165 | 0 |
| RRAGA | RRAGA | Q7L523 | Ras-related GTP-binding protein A | chr9 | GO:0008219 | Not Cancer Driver | No | 30 | 0.096 | 0 | 0 | 0.0 | 0 |
| RYR2 | RYR2 | Q92736 | Ryanodine receptor 2 | chr1 | GO:0008219 | Not Cancer Driver | No | 1703 | 0.343 | 782 | 281 | 0.359 | 51 |
| SCRIB_ENST00000320476 | SCRIB | Q14160 | Protein scribble homolog | chr8 | GO:0008219 | Not Cancer Driver | No | 196 | 0.12 | 1064 | 135 | 0.127 | 2 |
| SH3GLB1_ENST00000370558 | SH3GLB1 | Q9Y371 | Endophilin-B1 | chr1 | GO:0008219 | Not Cancer Driver | No | 41 | 0.112 | 82 | 10 | 0.122 | 0 |
| SIGMAR1 | SIGMAR1 | Q99720 | Sigma non-opioid intracellular receptor 1 | chr9 | GO:0008219 | Not Cancer Driver | No | 22 | 0.099 | 2 | 0 | 0.0 | 1 |
| SIX3 | SIX3 | O95343 | Homeobox protein SIX3 | chr2 | GO:0008219 | Not Cancer Driver | No | 44 | 0.133 | 196 | 22 | 0.112 | 32 |
| SLC1A1 | SLC1A1 | P43005 | Excitatory amino acid transporter 3 | chr9 | GO:0008219 | Not Cancer Driver | No | 69 | 0.132 | 17 | 4 | 0.235 | 1 |
| SLIT2 | SLIT2 | O94813 | Slit homolog 2 protein | chr4 | GO:0008219 | Not Cancer Driver | No | 428 | 0.28 | 31 | 13 | 0.419 | 0 |
| SLIT3_ENST00000519560 | SLIT3 | O75094 | Slit homolog 3 protein | chr5 | GO:0008219 | Not Cancer Driver | No | 351 | 0.23 | 40 | 9 | 0.225 | 0 |
| SNCAIP_ENST00000261368 | SNCAIP | Q9Y6H5 | Synphilin-1 | chr5 | GO:0008219 | Not Cancer Driver | No | 221 | 0.24 | 719 | 189 | 0.263 | 0 |
| SPATA2_ENST00000289431 | SPATA2 | Q9UM82 | Spermatogenesis-associated protein 2 | chr20 | GO:0008219 | Not Cancer Driver | No | 70 | 0.135 | 235 | 39 | 0.166 | 0 |
| SPI1_ENST00000378538 | SPI1 | P17947 | Transcription factor PU.1 | chr11 | GO:0008219 | Not Cancer Driver | No | 46 | 0.17 | 187 | 34 | 0.182 | 0 |
| STK11 | STK11 | Q15831 | Serine/threonine-protein kinase STK11 | chr19 | GO:0008219 | Census, Compendium | Yes | 75 | 0.173 | 135 | 14 | 0.104 | 9 |
| STK3_ENST00000419617 | STK3 | Q13188 | Serine/threonine-protein kinase 3 | chr8 | GO:0008219 | Not Cancer Driver | No | 70 | 0.143 | 241 | 32 | 0.133 | 0 |
| STK4 | STK4 | Q13043 | Serine/threonine-protein kinase 4 | chr20 | GO:0008219 | Not Cancer Driver | No | 70 | 0.144 | 231 | 30 | 0.13 | 0 |
| SUSD6 | SUSD6 | Q92537 | Sushi domain-containing protein 6 | chr14 | GO:0008219 | Not Cancer Driver | No | 27 | 0.089 | 134 | 8 | 0.06 | 0 |
| TBC1D24_ENST00000293970 | TBC1D24 | Q9ULP9 | TBC1 domain family member 24 | chr16 | GO:0008219 | Not Cancer Driver | No | 59 | 0.106 | 33 | 2 | 0.061 | 16 |
| TBX1_ENST00000329705 | TBX1 | O43435 | T-box transcription factor TBX1 | chr22 | GO:0008219 | Not Cancer Driver | No | 35 | 0.088 | 197 | 12 | 0.061 | 4 |
| TFDP1 | TFDP1 | Q14186 | Transcription factor Dp-1 | chr13 | GO:0008219 | Not Cancer Driver | No | 82 | 0.2 | 245 | 47 | 0.192 | 0 |
| TGFB2_ENST00000366930 | TGFB2 | P61812 | Transforming growth factor beta-2 proprotein | chr1 | GO:0008219 | Not Cancer Driver | No | 63 | 0.152 | 47 | 8 | 0.17 | 3 |
| TGFBR2_ENST00000295754 | TGFBR2 | P37173 | TGF-beta receptor type-2 | chr3 | GO:0008219 | Census, Compendium | Yes | 106 | 0.187 | 60 | 16 | 0.267 | 25 |
| THRB_ENST00000415021 | THRB | P10828 | Thyroid hormone receptor beta | chr3 | GO:0008219 | Not Cancer Driver | No | 87 | 0.189 | 113 | 28 | 0.248 | 33 |
| TMEM79_ENST00000295694 | TMEM79 | Q9BSE2 | Transmembrane protein 79 | chr1 | GO:0008219 | Not Cancer Driver | No | 56 | 0.142 | 149 | 20 | 0.134 | 0 |
| TMTC4_ENST00000376234 | TMTC4 | Q5T4D3 | Protein O-mannosyl-transferase TMTC4 | chr13 | GO:0008219 | Not Cancer Driver | No | 105 | 0.142 | 0 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0008219 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF21 | TNFRSF21 | O75509 | Tumor necrosis factor receptor superfamily member 21 | chr6 | GO:0008219 | Not Cancer Driver | No | 98 | 0.15 | 280 | 46 | 0.164 | 0 |
| TP53INP1 | TP53INP1 | Q96A56 | Tumor protein p53-inducible nuclear protein 1 | chr8 | GO:0008219 | Not Cancer Driver | No | 32 | 0.133 | 134 | 20 | 0.149 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0008219 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TRAF2 | TRAF2 | Q12933 | TNF receptor-associated factor 2 | chr9 | GO:0008219 | Not Cancer Driver | No | 63 | 0.126 | 4 | 1 | 0.25 | 0 |
| TRAF3IP2_ENST00000392556 | TRAF3IP2 | O43734 | E3 ubiquitin ligase TRAF3IP2 | chr6 | GO:0008219 | Not Cancer Driver | No | 59 | 0.103 | 410 | 39 | 0.095 | 2 |
| TREM2 | TREM2 | Q9NZC2 | Triggering receptor expressed on myeloid cells 2 | chr6 | GO:0008219 | Not Cancer Driver | No | 43 | 0.187 | 27 | 2 | 0.074 | 1 |
| TRPM7 | TRPM7 | Q96QT4 | Transient receptor potential cation channel subfamily M member 7 | chr15 | GO:0008219 | Not Cancer Driver | No | 199 | 0.107 | 455 | 60 | 0.132 | 0 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | GO:0008219 | Census, Compendium | Yes | 192 | 0.106 | 563 | 50 | 0.089 | 53 |
| VAPA_ENST00000400000 | VAPA | Q9P0L0 | Vesicle-associated membrane protein-associated protein A | chr18 | GO:0008219 | Not Cancer Driver | No | 24 | 0.096 | 184 | 14 | 0.076 | 0 |
| XKR4 | XKR4 | Q5GH76 | XK-related protein 4 | chr8 | GO:0008219 | Not Cancer Driver | No | 163 | 0.251 | 123 | 33 | 0.268 | 0 |
| XKR5 | XKR5 | Q6UX68 | XK-related protein 5 | chr8 | GO:0008219 | Not Cancer Driver | No | 62 | 0.09 | 306 | 17 | 0.056 | 0 |
| XKR6 | XKR6 | Q5GH73 | XK-related protein 6 | chr8 | GO:0008219 | Not Cancer Driver | No | 88 | 0.137 | 118 | 14 | 0.119 | 0 |
| XKR7 | XKR7 | Q5GH72 | XK-related protein 7 | chr20 | GO:0008219 | Not Cancer Driver | No | 112 | 0.193 | 161 | 39 | 0.242 | 0 |
| XKR8 | XKR8 | Q9H6D3 | XK-related protein 8 | chr1 | GO:0008219 | Not Cancer Driver | No | 34 | 0.086 | 4 | 0 | 0.0 | 0 |
| XKR9 | XKR9 | Q5GH70 | XK-related protein 9 | chr8 | GO:0008219 | Not Cancer Driver | No | 72 | 0.193 | 0 | 0 | 0.0 | 0 |
| ZBP1 | ZBP1 | Q9H171 | Z-DNA-binding protein 1 | chr20 | GO:0008219 | Not Cancer Driver | No | 97 | 0.226 | 385 | 80 | 0.208 | 0 |
| ZMPSTE24 | ZMPSTE24 | O75844 | CAAX prenyl protease 1 homolog | chr1 | GO:0008219 | Not Cancer Driver | No | 67 | 0.141 | 23 | 0 | 0.0 | 3 |
| ZPR1 | ZPR1 | O75312 | Zinc finger protein ZPR1 | chr11 | GO:0008219 | Not Cancer Driver | No | 38 | 0.083 | 291 | 27 | 0.093 | 0 |