Total number of protein in "GO:0008203" GO term: 89
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABCA1 | ABCA1 | O95477 | Phospholipid-transporting ATPase ABCA1 | chr9 | GO:0008203 | Not Cancer Driver | No | 284 | 0.126 | 245 | 40 | 0.163 | 31 |
| ABCA5 | ABCA5 | Q8WWZ7 | Cholesterol transporter ABCA5 | chr17 | GO:0008203 | Not Cancer Driver | No | 214 | 0.13 | 52 | 5 | 0.096 | 0 |
| ABCG1 | ABCG1 | P45844 | ATP-binding cassette sub-family G member 1 | chr21 | GO:0008203 | Not Cancer Driver | No | 104 | 0.153 | 32 | 5 | 0.156 | 0 |
| AKR1D1 | AKR1D1 | P51857 | Aldo-keto reductase family 1 member D1 | chr7 | GO:0008203 | Not Cancer Driver | No | 89 | 0.273 | 15 | 3 | 0.2 | 5 |
| ANGPTL3 | ANGPTL3 | Q9Y5C1 | Angiopoietin-related protein 3 | chr1 | GO:0008203 | Not Cancer Driver | No | 52 | 0.113 | 154 | 26 | 0.169 | 0 |
| APOA1_ENST00000375320 | APOA1 | P02647 | Apolipoprotein A-I | chr11 | GO:0008203 | Not Cancer Driver | No | 28 | 0.105 | 131 | 8 | 0.061 | 3 |
| APOA2 | APOA2 | P02652 | Apolipoprotein A-II | chr1 | GO:0008203 | Not Cancer Driver | No | 13 | 0.13 | 0 | 0 | 0.0 | 0 |
| APOA4 | APOA4 | P06727 | Apolipoprotein A-IV | chr11 | GO:0008203 | Not Cancer Driver | No | 77 | 0.194 | 298 | 65 | 0.218 | 0 |
| APOB | APOB | P04114 | Apolipoprotein B-100 | chr2 | GO:0008203 | Not Cancer Driver | No | 1022 | 0.224 | 315 | 72 | 0.229 | 3 |
| APOBR | APOBR | Q0VD83 | Apolipoprotein B receptor | chr16 | GO:0008203 | Not Cancer Driver | No | 166 | 0.151 | 1063 | 163 | 0.153 | 0 |
| APOE | APOE | P02649 | Apolipoprotein E | chr19 | GO:0008203 | Not Cancer Driver | No | 25 | 0.079 | 124 | 6 | 0.048 | 12 |
| APOF | APOF | Q13790 | Apolipoprotein F | chr12 | GO:0008203 | Not Cancer Driver | No | 41 | 0.126 | 51 | 9 | 0.176 | 0 |
| APOL1_ENST00000397279 | APOL1 | O14791 | Apolipoprotein L1 | chr22 | GO:0008203 | Not Cancer Driver | No | 51 | 0.128 | 82 | 9 | 0.11 | 2 |
| APOL2 | APOL2 | Q9BQE5 | Apolipoprotein L2 | chr22 | GO:0008203 | Not Cancer Driver | No | 34 | 0.101 | 94 | 8 | 0.085 | 0 |
| APP | APP | P05067 | Amyloid-beta precursor protein | chr21 | GO:0008203 | Not Cancer Driver | No | 128 | 0.166 | 418 | 71 | 0.17 | 17 |
| CAT | CAT | P04040 | Catalase | chr11 | GO:0008203 | Not Cancer Driver | No | 70 | 0.133 | 176 | 18 | 0.102 | 0 |
| CEBPA | CEBPA | P49715 | CCAAT/enhancer-binding protein alpha | chr19 | GO:0008203 | Census, Compendium | Yes | 12 | 0.034 | 342 | 12 | 0.035 | 1 |
| CEL | CEL | P19835 | Bile salt-activated lipase | chr9 | GO:0008203 | Not Cancer Driver | No | 101 | 0.134 | 280 | 40 | 0.143 | 0 |
| CES1_ENST00000361503 | CES1 | P23141 | Liver carboxylesterase 1 | chr16 | GO:0008203 | Not Cancer Driver | No | 138 | 0.243 | 41 | 2 | 0.049 | 0 |
| CETP | CETP | P11597 | Cholesteryl ester transfer protein | chr16 | GO:0008203 | Not Cancer Driver | No | 58 | 0.118 | 0 | 0 | 0.0 | 3 |
| CH25H | CH25H | O95992 | Cholesterol 25-hydroxylase | chr10 | GO:0008203 | Not Cancer Driver | No | 37 | 0.136 | 0 | 0 | 0.0 | 0 |
| CLN6 | CLN6 | Q9NWW5 | Ceroid-lipofuscinosis neuronal protein 6 | chr15 | GO:0008203 | Not Cancer Driver | No | 28 | 0.09 | 13 | 0 | 0.0 | 24 |
| CLN8 | CLN8 | Q9UBY8 | Protein CLN8 | chr8 | GO:0008203 | Not Cancer Driver | No | 45 | 0.157 | 16 | 2 | 0.125 | 16 |
| CUBN | CUBN | O60494 | Cubilin | chr10 | GO:0008203 | Not Cancer Driver | No | 709 | 0.196 | 272 | 54 | 0.199 | 2 |
| CYP11A1 | CYP11A1 | P05108 | Cholesterol side-chain cleavage enzyme, mitochondrial | chr15 | GO:0008203 | Not Cancer Driver | No | 92 | 0.177 | 27 | 6 | 0.222 | 6 |
| CYP11B1 | CYP11B1 | P15538 | Cytochrome P450 11B1, mitochondrial | chr8 | GO:0008203 | Not Cancer Driver | No | 177 | 0.352 | 7 | 1 | 0.143 | 50 |
| CYP11B2 | CYP11B2 | P19099 | Cytochrome P450 11B2, mitochondrial | chr8 | GO:0008203 | Not Cancer Driver | No | 148 | 0.294 | 6 | 0 | 0.0 | 6 |
| CYP1A2 | CYP1A2 | P05177 | Cytochrome P450 1A2 | chr15 | GO:0008203 | Not Cancer Driver | No | 93 | 0.18 | 23 | 3 | 0.13 | 0 |
| CYP27A1 | CYP27A1 | Q02318 | Sterol 26-hydroxylase, mitochondrial | chr2 | GO:0008203 | Not Cancer Driver | No | 69 | 0.13 | 47 | 11 | 0.234 | 7 |
| CYP2C9 | CYP2C9 | P11712 | Cytochrome P450 2C9 | chr10 | GO:0008203 | Not Cancer Driver | No | 122 | 0.249 | 36 | 14 | 0.389 | 0 |
| CYP2D6_ENST00000645361 | CYP2D6 | P10635 | Cytochrome P450 2D6 | chr22 | GO:0008203 | Not Cancer Driver | No | 76 | 0.153 | 66 | 8 | 0.121 | 0 |
| CYP39A1 | CYP39A1 | Q9NYL5 | 24-hydroxycholesterol 7-alpha-hydroxylase | chr6 | GO:0008203 | Not Cancer Driver | No | 61 | 0.13 | 3 | 0 | 0.0 | 0 |
| CYP3A4 | CYP3A4 | P08684 | Cytochrome P450 3A4 | chr7 | GO:0008203 | Not Cancer Driver | No | 91 | 0.181 | 22 | 2 | 0.091 | 1 |
| CYP46A1 | CYP46A1 | Q9Y6A2 | Cholesterol 24-hydroxylase | chr14 | GO:0008203 | Not Cancer Driver | No | 92 | 0.184 | 23 | 4 | 0.174 | 0 |
| CYP7A1 | CYP7A1 | P22680 | Cytochrome P450 7A1 | chr8 | GO:0008203 | Not Cancer Driver | No | 109 | 0.216 | 48 | 8 | 0.167 | 0 |
| CYP7B1 | CYP7B1 | O75881 | Cytochrome P450 7B1 | chr8 | GO:0008203 | Not Cancer Driver | No | 133 | 0.263 | 0 | 0 | 0.0 | 11 |
| DHCR24 | DHCR24 | Q15392 | Delta(24)-sterol reductase | chr1 | GO:0008203 | Not Cancer Driver | No | 55 | 0.107 | 0 | 0 | 0.0 | 6 |
| DHCR7 | DHCR7 | Q9UBM7 | 7-dehydrocholesterol reductase | chr11 | GO:0008203 | Not Cancer Driver | No | 85 | 0.179 | 7 | 1 | 0.143 | 53 |
| DISP3 | DISP3 | Q9P2K9 | Protein dispatched homolog 3 | chr1 | GO:0008203 | Not Cancer Driver | No | 320 | 0.23 | 172 | 44 | 0.256 | 0 |
| EBP | EBP | Q15125 | 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase | chrX | GO:0008203 | Not Cancer Driver | No | 30 | 0.13 | 9 | 0 | 0.0 | 9 |
| ERLIN1 | ERLIN1 | O75477 | Erlin-1 | chr10 | GO:0008203 | Not Cancer Driver | No | 29 | 0.083 | 46 | 4 | 0.087 | 1 |
| ERLIN2_ENST00000519638 | ERLIN2 | O94905 | Erlin-2 | chr8 | GO:0008203 | Not Cancer Driver | No | 38 | 0.112 | 22 | 3 | 0.136 | 0 |
| FDX1 | FDX1 | P10109 | Adrenodoxin, mitochondrial | chr11 | GO:0008203 | Not Cancer Driver | No | 12 | 0.065 | 61 | 2 | 0.033 | 0 |
| FDXR_ENST00000293195 | FDXR | P22570 | NADPH:adrenodoxin oxidoreductase, mitochondrial | chr17 | GO:0008203 | Not Cancer Driver | No | 68 | 0.138 | 102 | 14 | 0.137 | 4 |
| GBA2 | GBA2 | Q9HCG7 | Non-lysosomal glucosylceramidase | chr9 | GO:0008203 | Not Cancer Driver | No | 96 | 0.104 | 157 | 12 | 0.076 | 3 |
| GBA_ENST00000368373 | GBA | P04062 | Lysosomal acid glucosylceramidase | chr1 | GO:0008203 | Not Cancer Driver | No | 74 | 0.138 | 38 | 5 | 0.132 | 171 |
| HDLBP_ENST00000391976 | HDLBP | Q00341 | Vigilin | chr2 | GO:0008203 | Not Cancer Driver | No | 195 | 0.154 | 555 | 87 | 0.157 | 0 |
| IL4 | IL4 | P05112 | Interleukin-4 | chr5 | GO:0008203 | Not Cancer Driver | No | 18 | 0.118 | 0 | 0 | 0.0 | 0 |
| LCAT | LCAT | P04180 | Phosphatidylcholine-sterol acyltransferase | chr16 | GO:0008203 | Not Cancer Driver | No | 43 | 0.098 | 28 | 2 | 0.071 | 34 |
| LDLR | LDLR | P01130 | Low-density lipoprotein receptor | chr19 | GO:0008203 | Not Cancer Driver | No | 119 | 0.138 | 63 | 3 | 0.048 | 104 |
| LDLRAP1 | LDLRAP1 | Q5SW96 | Low density lipoprotein receptor adapter protein 1 | chr1 | GO:0008203 | Not Cancer Driver | No | 36 | 0.117 | 119 | 17 | 0.143 | 1 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0008203 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| LEPR | LEPR | P48357 | Leptin receptor | chr1 | GO:0008203 | Not Cancer Driver | No | 243 | 0.209 | 57 | 11 | 0.193 | 0 |
| LIMA1_ENST00000341247 | LIMA1 | Q9UHB6 | LIM domain and actin-binding protein 1 | chr12 | GO:0008203 | Not Cancer Driver | No | 88 | 0.116 | 687 | 81 | 0.118 | 0 |
| LIPC_ENST00000356113 | LIPC | P11150 | Hepatic triacylglycerol lipase | chr15 | GO:0008203 | Not Cancer Driver | No | 91 | 0.182 | 17 | 3 | 0.176 | 2 |
| LIPE | LIPE | Q05469 | Hormone-sensitive lipase | chr19 | GO:0008203 | Not Cancer Driver | No | 123 | 0.114 | 496 | 65 | 0.131 | 0 |
| LRP5 | LRP5 | O75197 | Low-density lipoprotein receptor-related protein 5 | chr11 | GO:0008203 | Not Cancer Driver | No | 253 | 0.157 | 188 | 28 | 0.149 | 55 |
| MBTPS1 | MBTPS1 | Q14703 | Membrane-bound transcription factor site-1 protease | chr16 | GO:0008203 | Not Cancer Driver | No | 140 | 0.133 | 206 | 36 | 0.175 | 1 |
| MBTPS2 | MBTPS2 | O43462 | Membrane-bound transcription factor site-2 protease | chrX | GO:0008203 | Not Cancer Driver | No | 63 | 0.121 | 16 | 4 | 0.25 | 9 |
| MT3 | MT3 | P25713 | Metallothionein-3 | chr16 | GO:0008203 | Not Cancer Driver | No | 7 | 0.103 | 0 | 0 | 0.0 | 0 |
| NFE2L1 | NFE2L1 | Q14494 | Endoplasmic reticulum membrane sensor NFE2L1 | chr17 | GO:0008203 | Not Cancer Driver | No | 65 | 0.084 | 511 | 32 | 0.063 | 0 |
| NPC1 | NPC1 | O15118 | NPC intracellular cholesterol transporter 1 | chr18 | GO:0008203 | Not Cancer Driver | No | 155 | 0.121 | 24 | 0 | 0.0 | 150 |
| NPC2 | NPC2 | P61916 | NPC intracellular cholesterol transporter 2 | chr14 | GO:0008203 | Not Cancer Driver | No | 8 | 0.053 | 0 | 0 | 0.0 | 7 |
| NR0B2 | NR0B2 | Q15466 | Nuclear receptor subfamily 0 group B member 2 | chr1 | GO:0008203 | Not Cancer Driver | No | 35 | 0.136 | 10 | 2 | 0.2 | 0 |
| NSDHL | NSDHL | Q15738 | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating | chrX | GO:0008203 | Not Cancer Driver | No | 60 | 0.161 | 39 | 6 | 0.154 | 3 |
| OSBPL1A | OSBPL1A | Q9BXW6 | Oxysterol-binding protein-related protein 1 | chr18 | GO:0008203 | Not Cancer Driver | No | 110 | 0.116 | 314 | 27 | 0.086 | 0 |
| OSBPL5 | OSBPL5 | Q9H0X9 | Oxysterol-binding protein-related protein 5 | chr11 | GO:0008203 | Not Cancer Driver | No | 100 | 0.114 | 444 | 43 | 0.097 | 0 |
| PCSK9 | PCSK9 | Q8NBP7 | Proprotein convertase subtilisin/kexin type 9 | chr1 | GO:0008203 | Not Cancer Driver | No | 86 | 0.124 | 148 | 27 | 0.182 | 9 |
| PIP4P1_ENST00000250489 | PIP4P1 | Q86T03 | Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase | chr14 | GO:0008203 | Not Cancer Driver | No | 36 | 0.13 | 78 | 4 | 0.051 | 0 |
| PON1 | PON1 | P27169 | Serum paraoxonase/arylesterase 1 | chr7 | GO:0008203 | Not Cancer Driver | No | 80 | 0.225 | 10 | 9 | 0.9 | 0 |
| PPARD_ENST00000360694 | PPARD | Q03181 | Peroxisome proliferator-activated receptor delta | chr6 | GO:0008203 | Not Cancer Driver | No | 72 | 0.163 | 69 | 7 | 0.101 | 0 |
| RXRA | RXRA | P19793 | Retinoic acid receptor RXR-alpha | chr9 | GO:0008203 | Compendium | Yes | 90 | 0.195 | 184 | 26 | 0.141 | 0 |
| SC5D_ENST00000392789 | SC5D | O75845 | Lathosterol oxidase | chr11 | GO:0008203 | Not Cancer Driver | No | 43 | 0.144 | 21 | 3 | 0.143 | 3 |
| SCAP | SCAP | Q12770 | Sterol regulatory element-binding protein cleavage-activating protein | chr3 | GO:0008203 | Not Cancer Driver | No | 145 | 0.113 | 329 | 36 | 0.109 | 0 |
| SCARB1_ENST00000415380 | SCARB1 | Q8WTV0 | Scavenger receptor class B member 1 | chr12 | GO:0008203 | Not Cancer Driver | No | 53 | 0.096 | 6 | 1 | 0.167 | 0 |
| SCARF1 | SCARF1 | Q14162 | Scavenger receptor class F member 1 | chr17 | GO:0008203 | Not Cancer Driver | No | 90 | 0.108 | 340 | 61 | 0.179 | 0 |
| SMPD1 | SMPD1 | P17405 | Sphingomyelin phosphodiesterase | chr11 | GO:0008203 | Not Cancer Driver | No | 93 | 0.147 | 51 | 4 | 0.078 | 111 |
| SNX17 | SNX17 | Q15036 | Sorting nexin-17 | chr2 | GO:0008203 | Not Cancer Driver | No | 55 | 0.117 | 118 | 10 | 0.085 | 0 |
| SOAT1 | SOAT1 | P35610 | Sterol O-acyltransferase 1 | chr1 | GO:0008203 | Not Cancer Driver | No | 73 | 0.133 | 49 | 4 | 0.082 | 0 |
| SOAT2 | SOAT2 | O75908 | Sterol O-acyltransferase 2 | chr12 | GO:0008203 | Not Cancer Driver | No | 69 | 0.132 | 67 | 4 | 0.06 | 0 |
| SQLE | SQLE | Q14534 | Squalene monooxygenase | chr8 | GO:0008203 | Not Cancer Driver | No | 54 | 0.094 | 40 | 5 | 0.125 | 0 |
| SREBF1_ENST00000261646 | SREBF1 | P36956 | Sterol regulatory element-binding protein 1 | chr17 | GO:0008203 | Not Cancer Driver | No | 127 | 0.111 | 528 | 64 | 0.121 | 4 |
| SREBF2 | SREBF2 | Q12772 | Sterol regulatory element-binding protein 2 | chr22 | GO:0008203 | Not Cancer Driver | No | 124 | 0.109 | 357 | 43 | 0.12 | 0 |
| STAR | STAR | P49675 | Steroidogenic acute regulatory protein, mitochondrial | chr8 | GO:0008203 | Not Cancer Driver | No | 45 | 0.158 | 85 | 10 | 0.118 | 7 |
| STARD3 | STARD3 | Q14849 | StAR-related lipid transfer protein 3 | chr17 | GO:0008203 | Not Cancer Driver | No | 51 | 0.115 | 34 | 6 | 0.176 | 0 |
| SULT2A1 | SULT2A1 | Q06520 | Sulfotransferase 2A1 | chr19 | GO:0008203 | Not Cancer Driver | No | 50 | 0.175 | 0 | 0 | 0.0 | 0 |
| SULT2B1 | SULT2B1 | O00204 | Sulfotransferase 2B1 | chr19 | GO:0008203 | Not Cancer Driver | No | 42 | 0.115 | 100 | 11 | 0.11 | 0 |
| TSKU_ENST00000333090 | TSKU | Q8WUA8 | Tsukushi | chr11 | GO:0008203 | Not Cancer Driver | No | 53 | 0.15 | 44 | 6 | 0.136 | 0 |
| VLDLR | VLDLR | P98155 | Very low-density lipoprotein receptor | chr9 | GO:0008203 | Not Cancer Driver | No | 90 | 0.103 | 55 | 3 | 0.055 | 0 |