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Total number of protein in "GO:0008094" GO term:  77

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ATAD5 ATAD5 Q96QE3 ATPase family AAA domain-containing protein 5 chr17 GO:0008094 Not Cancer Driver No 200 0.108 1075 112 0.104 0
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0008094 Census, Compendium Yes 487 0.195 1672 301 0.18 33
BLM BLM P54132 Bloom syndrome protein chr15 GO:0008094 Census Yes 153 0.108 667 70 0.105 8
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 GO:0008094 Not Cancer Driver No 309 0.101 2187 218 0.1 2
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0008094 Census Yes 174 0.139 397 59 0.149 6
BTAF1 BTAF1 O14981 TATA-binding protein-associated factor 172 chr10 GO:0008094 Not Cancer Driver No 215 0.116 360 52 0.144 0
CDK7 CDK7 P50613 Cyclin-dependent kinase 7 chr5 GO:0008094 Not Cancer Driver No 41 0.118 38 5 0.132 0
CECR2_ENST00000342247 CECR2 Q9BXF3 Cat eye syndrome critical region protein 2 chr22 GO:0008094 Not Cancer Driver No 222 0.15 1192 183 0.154 0
CHD1 CHD1 O14646 Chromodomain-helicase-DNA-binding protein 1 chr5 GO:0008094 Not Cancer Driver No 172 0.101 975 109 0.112 4
CHD2 CHD2 O14647 Chromodomain-helicase-DNA-binding protein 2 chr15 GO:0008094 Census, Compendium Yes 222 0.121 1051 136 0.129 2
CHD3_ENST00000330494 CHD3 Q12873 Chromodomain-helicase-DNA-binding protein 3 chr17 GO:0008094 Not Cancer Driver No 235 0.117 1015 122 0.12 18
CHD4 CHD4 Q14839 Chromodomain-helicase-DNA-binding protein 4 chr12 GO:0008094 Census, Compendium Yes 419 0.219 974 177 0.182 6
CHD5 CHD5 Q8TDI0 Chromodomain-helicase-DNA-binding protein 5 chr1 GO:0008094 Not Cancer Driver No 365 0.187 931 183 0.197 0
CHD6 CHD6 Q8TD26 Chromodomain-helicase-DNA-binding protein 6 chr20 GO:0008094 Not Cancer Driver No 393 0.145 1469 213 0.145 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0008094 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0008094 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHTF18 CHTF18 Q8WVB6 Chromosome transmission fidelity protein 18 homolog chr16 GO:0008094 Not Cancer Driver No 114 0.117 503 56 0.111 0
CHTF8_ENST00000398235 CHTF8 P0CG13 Chromosome transmission fidelity protein 8 homolog chr16 GO:0008094 Not Cancer Driver No 13 0.107 7 0 0.0 0
DDX1 DDX1 Q92499 ATP-dependent RNA helicase DDX1 chr2 GO:0008094 Not Cancer Driver No 82 0.111 91 15 0.165 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0008094 Not Cancer Driver No 154 0.159 280 55 0.196 1
DHX36 DHX36 Q9H2U1 ATP-dependent DNA/RNA helicase DHX36 chr3 GO:0008094 Not Cancer Driver No 159 0.158 222 39 0.176 0
DHX9 DHX9 Q08211 ATP-dependent RNA helicase A chr1 GO:0008094 Compendium Yes 182 0.143 331 42 0.127 0
DMC1 DMC1 Q14565 Meiotic recombination protein DMC1/LIM15 homolog chr22 GO:0008094 Not Cancer Driver No 39 0.115 49 5 0.102 0
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0008094 Not Cancer Driver No 120 0.113 52 8 0.154 3
DSCC1 DSCC1 Q9BVC3 Sister chromatid cohesion protein DCC1 chr8 GO:0008094 Not Cancer Driver No 28 0.071 41 4 0.098 0
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0008094 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0008094 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC6L ERCC6L Q2NKX8 DNA excision repair protein ERCC-6-like chrX GO:0008094 Not Cancer Driver No 137 0.11 532 72 0.135 0
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0008094 Not Cancer Driver No 268 0.131 898 128 0.143 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0008094 Not Cancer Driver No 139 0.133 192 32 0.167 0
G3BP1 G3BP1 Q13283 Ras GTPase-activating protein-binding protein 1 chr5 GO:0008094 Not Cancer Driver No 85 0.182 352 65 0.185 0
HELB HELB Q8NG08 DNA helicase B chr12 GO:0008094 Not Cancer Driver No 140 0.129 300 38 0.127 0
HELQ HELQ Q8TDG4 Helicase POLQ-like chr4 GO:0008094 Not Cancer Driver No 134 0.122 273 19 0.07 0
HLTF_ENST00000494055 HLTF Q14527 Helicase-like transcription factor chr3 GO:0008094 Not Cancer Driver No 121 0.12 353 40 0.113 0
IGHMBP2 IGHMBP2 P38935 DNA-binding protein SMUBP-2 chr11 GO:0008094 Not Cancer Driver No 136 0.137 354 53 0.15 31
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0008094 Compendium Yes 173 0.111 682 76 0.111 0
MCM6 MCM6 Q14566 DNA replication licensing factor MCM6 chr2 GO:0008094 Not Cancer Driver No 101 0.123 122 13 0.107 0
MSH2 MSH2 P43246 DNA mismatch repair protein Msh2 chr2 GO:0008094 Census Yes 92 0.099 37 4 0.108 70
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0008094 Census Yes 154 0.113 386 41 0.106 6
MYO18A MYO18A Q92614 Unconventional myosin-XVIIIa chr17 GO:0008094 Not Cancer Driver No 268 0.13 1237 176 0.142 0
PIF1_ENST00000559239 PIF1 Q9H611 ATP-dependent DNA helicase PIF1 chr15 GO:0008094 Not Cancer Driver No 54 0.084 209 11 0.053 0
RAD17 RAD17 O75943 Cell cycle checkpoint protein RAD17 chr5 GO:0008094 Census Yes 78 0.115 207 19 0.092 0
RAD51B_ENST00000487270 RAD51B O15315 DNA repair protein RAD51 homolog 2 chr14 GO:0008094 Census Yes 45 0.117 13 0 0.0 0
RAD51C RAD51C O43502 DNA repair protein RAD51 homolog 3 chr17 GO:0008094 Not Cancer Driver No 47 0.125 18 2 0.111 6
RAD51D_ENST00000394589 RAD51D O75771 DNA repair protein RAD51 homolog 4 chr17 GO:0008094 Not Cancer Driver No 34 0.104 49 10 0.204 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0008094 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD54B RAD54B Q9Y620 DNA repair and recombination protein RAD54B chr8 GO:0008094 Not Cancer Driver No 112 0.123 120 16 0.133 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0008094 Not Cancer Driver No 79 0.106 124 13 0.105 0
RBBP4 RBBP4 Q09028 Histone-binding protein RBBP4 chr1 GO:0008094 Not Cancer Driver No 53 0.125 169 23 0.136 0
RECQL4 RECQL4 O94761 ATP-dependent DNA helicase Q4 chr8 GO:0008094 Census, Compendium Yes 138 0.114 608 71 0.117 1
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0008094 Not Cancer Driver No 132 0.133 495 71 0.143 0
RECQL_ENST00000421138 RECQL P46063 ATP-dependent DNA helicase Q1 chr12 GO:0008094 Not Cancer Driver No 67 0.103 91 5 0.055 0
RFC1 RFC1 P35251 Replication factor C subunit 1 chr4 GO:0008094 Not Cancer Driver No 147 0.128 674 82 0.122 0
RFC2 RFC2 P35250 Replication factor C subunit 2 chr7 GO:0008094 Not Cancer Driver No 45 0.127 39 6 0.154 0
RFC3 RFC3 P40938 Replication factor C subunit 3 chr13 GO:0008094 Not Cancer Driver No 31 0.087 13 1 0.077 0
RFC4_ENST00000296273 RFC4 P35249 Replication factor C subunit 4 chr3 GO:0008094 Not Cancer Driver No 58 0.16 50 8 0.16 0
RFC5 RFC5 P40937 Replication factor C subunit 5 chr12 GO:0008094 Not Cancer Driver No 38 0.112 20 1 0.05 0
RUVBL1 RUVBL1 Q9Y265 RuvB-like 1 chr3 GO:0008094 Not Cancer Driver No 54 0.118 67 7 0.104 0
RUVBL2 RUVBL2 Q9Y230 RuvB-like 2 chr19 GO:0008094 Not Cancer Driver No 62 0.134 100 13 0.13 0
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX GO:0008094 Compendium Yes 143 0.136 309 41 0.133 0
SMARCA2 SMARCA2 P51531 Probable global transcription activator SNF2L2 chr9 GO:0008094 Not Cancer Driver No 273 0.172 1009 160 0.159 42
SMARCA4 SMARCA4 P51532 Transcription activator BRG1 chr19 GO:0008094 Census, Compendium Yes 349 0.212 1072 195 0.182 5
SMARCA5 SMARCA5 O60264 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 chr4 GO:0008094 Not Cancer Driver No 116 0.11 363 48 0.132 0
SMARCAD1_ENST00000354268 SMARCAD1 Q9H4L7 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 chr4 GO:0008094 Not Cancer Driver No 129 0.126 388 50 0.129 0
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0008094 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMC3 SMC3 Q9UQE7 Structural maintenance of chromosomes protein 3 chr10 GO:0008094 Not Cancer Driver No 149 0.122 605 70 0.116 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0008094 Not Cancer Driver No 59 0.149 26 5 0.192 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0008094 Compendium Yes 150 0.098 508 59 0.116 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 GO:0008094 Not Cancer Driver No 154 0.095 543 46 0.085 0
TTF2 TTF2 Q9UNY4 Transcription termination factor 2 chr1 GO:0008094 Not Cancer Driver No 118 0.102 550 50 0.091 0
TWNK TWNK Q96RR1 Twinkle mtDNA helicase chr10 GO:0008094 Not Cancer Driver No 95 0.139 135 11 0.081 38
UPF1 UPF1 Q92900 Regulator of nonsense transcripts 1 chr19 GO:0008094 Not Cancer Driver No 146 0.129 329 36 0.109 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0008094 Census, Compendium Yes 164 0.115 373 41 0.11 2
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0008094 Not Cancer Driver No 36 0.129 9 1 0.111 2
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0008094 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0008094 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0008094 Not Cancer Driver No 66 0.108 140 12 0.086 0