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Total number of protein in "GO:0008021" GO term:  121

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AMPH AMPH P49418 Amphiphysin chr7 GO:0008021 Not Cancer Driver No 202 0.291 473 131 0.277 0
APBA1 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 GO:0008021 Not Cancer Driver No 149 0.178 556 103 0.185 0
APBA2_ENST00000561069 APBA2 Q99767 Amyloid-beta A4 precursor protein-binding family A member 2 chr15 GO:0008021 Not Cancer Driver No 184 0.246 429 117 0.273 0
APH1A APH1A Q96BI3 Gamma-secretase subunit APH-1A chr1 GO:0008021 Not Cancer Driver No 32 0.121 0 0 0.0 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0008021 Not Cancer Driver No 128 0.166 418 71 0.17 17
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 GO:0008021 Not Cancer Driver No 40 0.114 0 0 0.0 0
BACE1 BACE1 P56817 Beta-secretase 1 chr11 GO:0008021 Not Cancer Driver No 55 0.11 53 5 0.094 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0008021 Not Cancer Driver No 47 0.19 79 19 0.241 1
BIN1 BIN1 O00499 Myc box-dependent-interacting protein 1 chr2 GO:0008021 Not Cancer Driver No 65 0.11 456 42 0.092 5
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0008021 Not Cancer Driver No 131 0.168 459 78 0.17 0
BSN BSN Q9UPA5 Protein bassoon chr3 GO:0008021 Not Cancer Driver No 531 0.135 3702 510 0.138 0
CDK16_ENST00000357227 CDK16 Q00536 Cyclin-dependent kinase 16 chrX GO:0008021 Not Cancer Driver No 55 0.111 139 30 0.216 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0008021 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLCN4 CLCN4 P51793 H(+)/Cl(-) exchange transporter 4 chrX GO:0008021 Not Cancer Driver No 118 0.155 62 13 0.21 11
CLCN5 CLCN5 P51795 H(+)/Cl(-) exchange transporter 5 chrX GO:0008021 Not Cancer Driver No 138 0.169 81 6 0.074 32
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0008021 Not Cancer Driver No 58 0.132 69 10 0.145 9
COPS4_ENST00000264389 COPS4 Q9BT78 COP9 signalosome complex subunit 4 chr4 GO:0008021 Not Cancer Driver No 50 0.123 13 0 0.0 0
COPS5 COPS5 Q92905 COP9 signalosome complex subunit 5 chr8 GO:0008021 Not Cancer Driver No 36 0.108 32 7 0.219 0
CTTNBP2 CTTNBP2 Q8WZ74 Cortactin-binding protein 2 chr7 GO:0008021 Not Cancer Driver No 247 0.149 864 137 0.159 0
DDC DDC P20711 Aromatic-L-amino-acid decarboxylase chr7 GO:0008021 Not Cancer Driver No 98 0.204 5 0 0.0 9
DISC1_ENST00000439617 DISC1 Q9NRI5 Disrupted in schizophrenia 1 protein chr1 GO:0008021 Not Cancer Driver No 132 0.155 514 82 0.16 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0008021 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMXL2_ENST00000251076 DMXL2 Q8TDJ6 DmX-like protein 2 chr15 GO:0008021 Not Cancer Driver No 428 0.141 738 102 0.138 2
GABBR1 GABBR1 Q9UBS5 Gamma-aminobutyric acid type B receptor subunit 1 chr6 GO:0008021 Not Cancer Driver No 150 0.156 142 17 0.12 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0008021 Not Cancer Driver No 47 0.141 138 17 0.123 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0008021 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0008021 Census, Compendium Yes 528 0.361 506 207 0.409 31
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0008021 Not Cancer Driver No 97 0.145 454 60 0.132 0
HCRT HCRT O43612 Orexin chr17 GO:0008021 Not Cancer Driver No 3 0.023 45 0 0.0 1
IQSEC1_ENST00000273221 IQSEC1 Q6DN90 IQ motif and SEC7 domain-containing protein 1 chr3 GO:0008021 Not Cancer Driver No 141 0.146 610 97 0.159 2
KCNK9 KCNK9 Q9NPC2 Potassium channel subfamily K member 9 chr8 GO:0008021 Not Cancer Driver No 139 0.372 58 22 0.379 2
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 GO:0008021 Not Cancer Driver No 253 0.139 633 106 0.167 1
KIRREL3 KIRREL3 Q8IZU9 Kin of IRRE-like protein 3 chr11 GO:0008021 Not Cancer Driver No 111 0.143 223 32 0.143 0
LAMP1 LAMP1 P11279 Lysosome-associated membrane glycoprotein 1 chr13 GO:0008021 Not Cancer Driver No 47 0.113 93 10 0.108 0
LGI3 LGI3 Q8N145 Leucine-rich repeat LGI family member 3 chr8 GO:0008021 Not Cancer Driver No 82 0.15 20 2 0.1 0
MFF MFF Q9GZY8 Mitochondrial fission factor chr2 GO:0008021 Not Cancer Driver No 59 0.173 264 47 0.178 0
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0008021 Not Cancer Driver No 189 0.252 40 17 0.425 4
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0008021 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTMR2 MTMR2 Q13614 Myotubularin-related protein 2 chr11 GO:0008021 Not Cancer Driver No 70 0.109 140 16 0.114 1
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0008021 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0008021 Not Cancer Driver No 32 0.093 202 16 0.079 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0008021 Not Cancer Driver No 66 0.274 93 25 0.269 1
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0008021 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0008021 Not Cancer Driver No 21 0.1 56 4 0.071 0
PDE4B PDE4B Q07343 cAMP-specific 3',5'-cyclic phosphodiesterase 4B chr1 GO:0008021 Not Cancer Driver No 119 0.162 363 42 0.116 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0008021 Census Yes 89 0.137 320 42 0.131 0
PICK1 PICK1 Q9NRD5 PRKCA-binding protein chr22 GO:0008021 Not Cancer Driver No 50 0.12 49 3 0.061 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0008021 Not Cancer Driver No 37 0.121 0 0 0.0 23
PRRT2_ENST00000645336 PRRT2 Q7Z6L0 Proline-rich transmembrane protein 2 chr16 GO:0008021 Not Cancer Driver No 45 0.132 268 32 0.119 7
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0008021 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTPRN PTPRN Q16849 Receptor-type tyrosine-protein phosphatase-like N chr2 GO:0008021 Not Cancer Driver No 142 0.145 498 73 0.147 0
RAB10 RAB10 P61026 Ras-related protein Rab-10 chr2 GO:0008021 Not Cancer Driver No 19 0.095 28 2 0.071 0
RAB11B RAB11B Q15907 Ras-related protein Rab-11B chr19 GO:0008021 Not Cancer Driver No 26 0.119 39 3 0.077 2
RAB12 RAB12 Q6IQ22 Ras-related protein Rab-12 chr18 GO:0008021 Not Cancer Driver No 22 0.09 72 3 0.042 0
RAB13 RAB13 P51153 Ras-related protein Rab-13 chr1 GO:0008021 Not Cancer Driver No 19 0.094 40 0 0.0 0
RAB15 RAB15 P59190 Ras-related protein Rab-15 chr14 GO:0008021 Not Cancer Driver No 18 0.085 50 5 0.1 0
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0008021 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAB3B RAB3B P20337 Ras-related protein Rab-3B chr1 GO:0008021 Not Cancer Driver No 36 0.164 25 6 0.24 0
RAB3C RAB3C Q96E17 Ras-related protein Rab-3C chr5 GO:0008021 Not Cancer Driver No 52 0.229 54 10 0.185 0
RAB3D_ENST00000589655 RAB3D O95716 Ras-related protein Rab-3D chr19 GO:0008021 Not Cancer Driver No 37 0.169 46 6 0.13 0
RAB40A RAB40A Q8WXH6 Ras-related protein Rab-40A chrX GO:0008021 Not Cancer Driver No 38 0.137 2 0 0.0 0
RAB40AL RAB40AL P0C0E4 Ras-related protein Rab-40A-like chrX GO:0008021 Not Cancer Driver No 46 0.165 7 0 0.0 0
RAB40B RAB40B Q12829 Ras-related protein Rab-40B chr17 GO:0008021 Not Cancer Driver No 32 0.115 39 5 0.128 0
RAB40C_ENST00000539661 RAB40C Q96S21 Ras-related protein Rab-40C chr16 GO:0008021 Not Cancer Driver No 46 0.164 38 10 0.263 0
RAB5A RAB5A P20339 Ras-related protein Rab-5A chr3 GO:0008021 Not Cancer Driver No 32 0.149 65 15 0.231 0
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 GO:0008021 Not Cancer Driver No 37 0.179 26 3 0.115 0
RAB8B RAB8B Q92930 Ras-related protein Rab-8B chr15 GO:0008021 Not Cancer Driver No 22 0.106 29 2 0.069 0
RABAC1 RABAC1 Q9UI14 Prenylated Rab acceptor protein 1 chr19 GO:0008021 Not Cancer Driver No 23 0.124 13 2 0.154 0
RNF112 RNF112 Q9ULX5 RING finger protein 112 chr17 GO:0008021 Not Cancer Driver No 86 0.136 168 26 0.155 0
ROGDI ROGDI Q9GZN7 Protein rogdi homolog chr16 GO:0008021 Not Cancer Driver No 21 0.073 19 2 0.105 0
RPH3A RPH3A Q9Y2J0 Rabphilin-3A chr12 GO:0008021 Not Cancer Driver No 155 0.223 427 105 0.246 0
SEPT2_ENST00000360051 SEPTIN2 Q15019 Septin-2 chr2 GO:0008021 Not Cancer Driver No 49 0.136 101 11 0.109 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0008021 Not Cancer Driver No 61 0.128 220 31 0.141 0
SEPT5 SEPTIN5 Q99719 Septin-5 chr22 GO:0008021 Not Cancer Driver No 50 0.136 76 5 0.066 0
SEPT6 SEPTIN6 Q14141 Septin-6 chrX GO:0008021 Not Cancer Driver No 69 0.159 161 25 0.155 0
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 GO:0008021 Not Cancer Driver No 105 0.204 23 7 0.304 1
SLC2A13 SLC2A13 Q96QE2 Proton myo-inositol cotransporter chr12 GO:0008021 Not Cancer Driver No 79 0.122 52 4 0.077 0
SLC2A8 SLC2A8 Q9NY64 Solute carrier family 2, facilitated glucose transporter member 8 chr9 GO:0008021 Not Cancer Driver No 28 0.059 19 0 0.0 0
SLC30A3 SLC30A3 Q99726 Zinc transporter 3 chr2 GO:0008021 Not Cancer Driver No 56 0.144 97 18 0.186 0
SLC40A1 SLC40A1 Q9NP59 Solute carrier family 40 member 1 chr2 GO:0008021 Not Cancer Driver No 63 0.11 48 3 0.062 12
SLC4A8 SLC4A8 Q2Y0W8 Electroneutral sodium bicarbonate exchanger 1 chr12 GO:0008021 Not Cancer Driver No 176 0.161 276 41 0.149 0
SLC6A17 SLC6A17 Q9H1V8 Sodium-dependent neutral amino acid transporter SLC6A17 chr1 GO:0008021 Not Cancer Driver No 119 0.164 67 10 0.149 2
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 GO:0008021 Not Cancer Driver No 61 0.296 176 49 0.278 1
SNAP91_ENST00000369694 SNAP91 O60641 Clathrin coat assembly protein AP180 chr6 GO:0008021 Not Cancer Driver No 203 0.224 636 118 0.186 0
SNAPIN SNAPIN O95295 SNARE-associated protein Snapin chr1 GO:0008021 Not Cancer Driver No 9 0.066 62 5 0.081 0
SNCAIP_ENST00000261368 SNCAIP Q9Y6H5 Synphilin-1 chr5 GO:0008021 Not Cancer Driver No 221 0.24 719 189 0.263 0
STON1 STON1 Q9Y6Q2 Stonin-1 chr2 GO:0008021 Not Cancer Driver No 139 0.189 215 45 0.209 0
STON2_ENST00000267540 STON2 Q8WXE9 Stonin-2 chr14 GO:0008021 Not Cancer Driver No 153 0.169 449 77 0.171 0
STX11 STX11 O75558 Syntaxin-11 chr6 GO:0008021 Not Cancer Driver No 71 0.247 48 7 0.146 0
STX12 STX12 Q86Y82 Syntaxin-12 chr1 GO:0008021 Not Cancer Driver No 21 0.076 156 9 0.058 0
STX19 STX19 Q8N4C7 Syntaxin-19 chr3 GO:0008021 Not Cancer Driver No 39 0.133 67 4 0.06 0
STX1A STX1A Q16623 Syntaxin-1A chr7 GO:0008021 Not Cancer Driver No 35 0.122 136 11 0.081 0
STX1B STX1B P61266 Syntaxin-1B chr16 GO:0008021 Not Cancer Driver No 38 0.132 155 20 0.129 2
STX2 STX2 P32856 Syntaxin-2 chr12 GO:0008021 Not Cancer Driver No 43 0.149 140 25 0.179 0
STX3 STX3 Q13277 Syntaxin-3 chr11 GO:0008021 Not Cancer Driver No 51 0.176 129 30 0.233 0
STX4 STX4 Q12846 Syntaxin-4 chr16 GO:0008021 Not Cancer Driver No 50 0.168 152 20 0.132 0
STX7 STX7 O15400 Syntaxin-7 chr6 GO:0008021 Not Cancer Driver No 29 0.111 164 14 0.085 0
STXBP5 STXBP5 Q5T5C0 Syntaxin-binding protein 5 chr6 GO:0008021 Not Cancer Driver No 128 0.111 344 46 0.134 0
SV2A SV2A Q7L0J3 Synaptic vesicle glycoprotein 2A chr1 GO:0008021 Not Cancer Driver No 134 0.181 150 31 0.207 0
SV2B SV2B Q7L1I2 Synaptic vesicle glycoprotein 2B chr15 GO:0008021 Not Cancer Driver No 143 0.209 97 31 0.32 0
SV2C SV2C Q496J9 Synaptic vesicle glycoprotein 2C chr5 GO:0008021 Not Cancer Driver No 155 0.213 134 33 0.246 0
SVOP SVOP Q8N4V2 Synaptic vesicle 2-related protein chr12 GO:0008021 Not Cancer Driver No 46 0.084 54 5 0.093 0
SYN1 SYN1 P17600 Synapsin-1 chrX GO:0008021 Not Cancer Driver No 75 0.106 445 27 0.061 0
SYN3 SYN3 O14994 Synapsin-3 chr22 GO:0008021 Not Cancer Driver No 94 0.162 292 47 0.161 0
SYNGR3 SYNGR3 O43761 Synaptogyrin-3 chr16 GO:0008021 Not Cancer Driver No 12 0.052 28 1 0.036 0
SYP SYP P08247 Synaptophysin chrX GO:0008021 Not Cancer Driver No 36 0.115 93 8 0.086 1
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0008021 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0008021 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT7_ENST00000263846 SYT7 O43581 Synaptotagmin-7 chr11 GO:0008021 Not Cancer Driver No 63 0.156 132 25 0.189 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0008021 Not Cancer Driver No 61 0.116 149 21 0.141 38
TMED9 TMED9 Q9BVK6 Transmembrane emp24 domain-containing protein 9 chr5 GO:0008021 Not Cancer Driver No 16 0.068 22 2 0.091 0
TMEM230_ENST00000379286 TMEM230 Q96A57 Transmembrane protein 230 chr20 GO:0008021 Not Cancer Driver No 23 0.192 0 0 0.0 0
TOR1A TOR1A O14656 Torsin-1A chr9 GO:0008021 Not Cancer Driver No 33 0.099 0 0 0.0 3
TPRG1L TPRG1L Q5T0D9 Tumor protein p63-regulated gene 1-like protein chr1 GO:0008021 Not Cancer Driver No 25 0.092 52 0 0.0 0
TRAPPC4 TRAPPC4 Q9Y296 Trafficking protein particle complex subunit 4 chr11 GO:0008021 Not Cancer Driver No 22 0.1 4 0 0.0 0
TRIM9 TRIM9 Q9C026 E3 ubiquitin-protein ligase TRIM9 chr14 GO:0008021 Not Cancer Driver No 142 0.2 112 22 0.196 0
VAMP2_ENST00000316509 VAMP2 P63027 Vesicle-associated membrane protein 2 chr17 GO:0008021 Not Cancer Driver No 7 0.06 47 4 0.085 3
VAMP4 VAMP4 O75379 Vesicle-associated membrane protein 4 chr1 GO:0008021 Not Cancer Driver No 9 0.064 80 6 0.075 0
VPS45_ENST00000644510 VPS45 Q9NRW7 Vacuolar protein sorting-associated protein 45 chr1 GO:0008021 Not Cancer Driver No 66 0.116 57 5 0.088 2
VTI1A VTI1A Q96AJ9 Vesicle transport through interaction with t-SNAREs homolog 1A chr10 GO:0008021 Census Yes 21 0.097 138 13 0.094 0
VTI1B VTI1B Q9UEU0 Vesicle transport through interaction with t-SNAREs homolog 1B chr14 GO:0008021 Not Cancer Driver No 25 0.108 192 20 0.104 0