Total number of protein in "GO:0008013" GO term: 85
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AJAP1 | AJAP1 | Q9UKB5 | Adherens junction-associated protein 1 | chr1 | GO:0008013 | Not Cancer Driver | No | 103 | 0.251 | 271 | 64 | 0.236 | 0 |
AMER1 | AMER1 | Q5JTC6 | APC membrane recruitment protein 1 | chrX | GO:0008013 | Census, Compendium | Yes | 234 | 0.206 | 1039 | 219 | 0.211 | 0 |
AMER2 | AMER2 | Q8N7J2 | APC membrane recruitment protein 2 | chr13 | GO:0008013 | Not Cancer Driver | No | 118 | 0.176 | 663 | 116 | 0.175 | 0 |
AMER3_ENST00000321420 | AMER3 | Q8N944 | APC membrane recruitment protein 3 | chr2 | GO:0008013 | Not Cancer Driver | No | 244 | 0.283 | 736 | 211 | 0.287 | 0 |
APC | APC | P25054 | Adenomatous polyposis coli protein | chr5 | GO:0008013 | Census, Compendium | Yes | 412 | 0.145 | 2406 | 345 | 0.143 | 22 |
APC2_ENST00000233607 | APC2 | O95996 | Adenomatous polyposis coli protein 2 | chr19 | GO:0008013 | Not Cancer Driver | No | 117 | 0.051 | 1725 | 78 | 0.045 | 0 |
AR | AR | P10275 | Androgen receptor | chrX | GO:0008013 | Census, Compendium | Yes | 196 | 0.213 | 443 | 88 | 0.199 | 169 |
ASH2L | ASH2L | Q9UBL3 | Set1/Ash2 histone methyltransferase complex subunit ASH2 | chr8 | GO:0008013 | Not Cancer Driver | No | 95 | 0.151 | 293 | 39 | 0.133 | 0 |
AXIN1 | AXIN1 | O15169 | Axin-1 | chr16 | GO:0008013 | Census, Compendium | Yes | 120 | 0.139 | 619 | 88 | 0.142 | 4 |
AXIN2 | AXIN2 | Q9Y2T1 | Axin-2 | chr17 | GO:0008013 | Census, Compendium | Yes | 114 | 0.135 | 547 | 77 | 0.141 | 0 |
BCL9 | BCL9 | O00512 | B-cell CLL/lymphoma 9 protein | chr1 | GO:0008013 | Census, Compendium | Yes | 219 | 0.154 | 1426 | 219 | 0.154 | 0 |
BCL9L | BCL9L | Q86UU0 | B-cell CLL/lymphoma 9-like protein | chr11 | GO:0008013 | Census, Compendium | Yes | 200 | 0.133 | 1495 | 200 | 0.134 | 0 |
BTRC | BTRC | Q9Y297 | F-box/WD repeat-containing protein 1A | chr10 | GO:0008013 | Not Cancer Driver | No | 80 | 0.132 | 45 | 4 | 0.089 | 0 |
CALCOCO1 | CALCOCO1 | Q9P1Z2 | Calcium-binding and coiled-coil domain-containing protein 1 | chr12 | GO:0008013 | Not Cancer Driver | No | 88 | 0.127 | 486 | 59 | 0.121 | 0 |
CARM1 | CARM1 | Q86X55 | Histone-arginine methyltransferase CARM1 | chr19 | GO:0008013 | Not Cancer Driver | No | 62 | 0.102 | 102 | 10 | 0.098 | 0 |
CBY1_ENST00000216029 | CBY1 | Q9Y3M2 | Protein chibby homolog 1 | chr22 | GO:0008013 | Not Cancer Driver | No | 13 | 0.103 | 98 | 11 | 0.112 | 0 |
CD2AP | CD2AP | Q9Y5K6 | CD2-associated protein | chr6 | GO:0008013 | Not Cancer Driver | No | 80 | 0.125 | 456 | 60 | 0.132 | 0 |
CDH1 | CDH1 | P12830 | Cadherin-1 | chr16 | GO:0008013 | Census, Compendium | Yes | 150 | 0.17 | 400 | 82 | 0.205 | 5 |
CDH2 | CDH2 | P19022 | Cadherin-2 | chr18 | GO:0008013 | Not Cancer Driver | No | 238 | 0.263 | 461 | 130 | 0.282 | 7 |
CDH26 | CDH26 | Q8IXH8 | Cadherin-like protein 26 | chr20 | GO:0008013 | Not Cancer Driver | No | 157 | 0.189 | 296 | 48 | 0.162 | 0 |
CDH5 | CDH5 | P33151 | Cadherin-5 | chr16 | GO:0008013 | Not Cancer Driver | No | 144 | 0.184 | 305 | 55 | 0.18 | 0 |
CDHR5 | CDHR5 | Q9HBB8 | Cadherin-related family member 5 | chr11 | GO:0008013 | Not Cancer Driver | No | 112 | 0.133 | 503 | 70 | 0.139 | 0 |
CHD8_ENST00000643469 | CHD8 | Q9HCK8 | Chromodomain-helicase-DNA-binding protein 8 | chr14 | GO:0008013 | Not Cancer Driver | No | 328 | 0.127 | 1411 | 148 | 0.105 | 0 |
CTNNA1 | CTNNA1 | P35221 | Catenin alpha-1 | chr5 | GO:0008013 | Census | Yes | 126 | 0.139 | 268 | 35 | 0.131 | 4 |
CTNNA2 | CTNNA2 | P26232 | Catenin alpha-2 | chr2 | GO:0008013 | Census | Yes | 387 | 0.406 | 307 | 130 | 0.423 | 0 |
CTNNA3 | CTNNA3 | Q9UI47 | Catenin alpha-3 | chr10 | GO:0008013 | Not Cancer Driver | No | 269 | 0.301 | 186 | 50 | 0.269 | 1 |
CTNNB1_ENST00000643977 | CTNNB1 | P35222 | Catenin beta-1 | chr3 | GO:0008013 | Census, Compendium | Yes | 415 | 0.531 | 288 | 301 | 1.045 | 14 |
CTNNBIP1_ENST00000377258 | CTNNBIP1 | Q9NSA3 | Beta-catenin-interacting protein 1 | chr1 | GO:0008013 | Not Cancer Driver | No | 8 | 0.099 | 64 | 7 | 0.109 | 0 |
CTNND2 | CTNND2 | Q9UQB3 | Catenin delta-2 | chr5 | GO:0008013 | Census | Yes | 386 | 0.315 | 837 | 254 | 0.303 | 0 |
CXADR | CXADR | P78310 | Coxsackievirus and adenovirus receptor | chr21 | GO:0008013 | Not Cancer Driver | No | 51 | 0.14 | 98 | 19 | 0.194 | 0 |
DACT1 | DACT1 | Q9NYF0 | Dapper homolog 1 | chr14 | GO:0008013 | Not Cancer Driver | No | 163 | 0.195 | 598 | 127 | 0.212 | 1 |
DACT2 | DACT2 | Q5SW24 | Dapper homolog 2 | chr6 | GO:0008013 | Not Cancer Driver | No | 35 | 0.045 | 655 | 30 | 0.046 | 0 |
DLG5 | DLG5 | Q8TDM6 | Disks large homolog 5 | chr10 | GO:0008013 | Not Cancer Driver | No | 230 | 0.12 | 1119 | 135 | 0.121 | 0 |
DVL1 | DVL1 | O14640 | Segment polarity protein dishevelled homolog DVL-1 | chr1 | GO:0008013 | Not Cancer Driver | No | 73 | 0.105 | 434 | 38 | 0.088 | 0 |
DVL3 | DVL3 | Q92997 | Segment polarity protein dishevelled homolog DVL-3 | chr3 | GO:0008013 | Not Cancer Driver | No | 97 | 0.135 | 437 | 58 | 0.133 | 0 |
EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0008013 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0008013 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
FOXO1 | FOXO1 | Q12778 | Forkhead box protein O1 | chr13 | GO:0008013 | Census, Compendium | Yes | 81 | 0.124 | 584 | 75 | 0.128 | 0 |
FOXO3 | FOXO3 | O43524 | Forkhead box protein O3 | chr6 | GO:0008013 | Census, Compendium | Yes | 70 | 0.104 | 595 | 68 | 0.114 | 0 |
FOXO4 | FOXO4 | P98177 | Forkhead box protein O4 | chrX | GO:0008013 | Census | Yes | 75 | 0.149 | 441 | 61 | 0.138 | 0 |
GJA1 | GJA1 | P17302 | Gap junction alpha-1 protein | chr6 | GO:0008013 | Not Cancer Driver | No | 86 | 0.225 | 110 | 26 | 0.236 | 50 |
GLI3 | GLI3 | P10071 | Transcriptional activator GLI3 | chr7 | GO:0008013 | Not Cancer Driver | No | 385 | 0.244 | 1352 | 327 | 0.242 | 7 |
GRIP1_ENST00000359742 | GRIP1 | Q9Y3R0 | Glutamate receptor-interacting protein 1 | chr12 | GO:0008013 | Not Cancer Driver | No | 203 | 0.18 | 568 | 101 | 0.178 | 0 |
GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0008013 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
GSKIP_ENST00000438650 | GSKIP | Q9P0R6 | GSK3B-interacting protein | chr14 | GO:0008013 | Not Cancer Driver | No | 11 | 0.079 | 32 | 1 | 0.031 | 0 |
HDAC6_ENST00000426196 | HDAC6 | Q9UBN7 | Histone deacetylase 6 | chrX | GO:0008013 | Not Cancer Driver | No | 178 | 0.147 | 409 | 59 | 0.144 | 0 |
KANK1_ENST00000382303 | KANK1 | Q14678 | KN motif and ankyrin repeat domain-containing protein 1 | chr9 | GO:0008013 | Not Cancer Driver | No | 183 | 0.135 | 804 | 100 | 0.124 | 0 |
KDM6B_ENST00000448097 | KDM6B | O15054 | Lysine-specific demethylase 6B | chr17 | GO:0008013 | Not Cancer Driver | No | 189 | 0.115 | 1278 | 142 | 0.111 | 2 |
LEF1 | LEF1 | Q9UJU2 | Lymphoid enhancer-binding factor 1 | chr4 | GO:0008013 | Census | Yes | 64 | 0.16 | 370 | 57 | 0.154 | 0 |
LZIC_ENST00000377213 | LZIC | Q8WZA0 | Protein LZIC | chr1 | GO:0008013 | Not Cancer Driver | No | 13 | 0.068 | 65 | 5 | 0.077 | 0 |
MED12 | MED12 | Q93074 | Mediator of RNA polymerase II transcription subunit 12 | chrX | GO:0008013 | Census, Compendium | Yes | 409 | 0.188 | 974 | 175 | 0.18 | 5 |
MED12L | MED12L | Q86YW9 | Mediator of RNA polymerase II transcription subunit 12-like protein | chr3 | GO:0008013 | Not Cancer Driver | No | 372 | 0.173 | 822 | 153 | 0.186 | 0 |
NR4A2_ENST00000409572 | NR4A2 | P43354 | Nuclear receptor subfamily 4 group A member 2 | chr2 | GO:0008013 | Not Cancer Driver | No | 110 | 0.184 | 261 | 38 | 0.146 | 0 |
NUMB_ENST00000355058 | NUMB | P49757 | Protein numb homolog | chr14 | GO:0008013 | Not Cancer Driver | No | 70 | 0.108 | 490 | 58 | 0.118 | 0 |
PIN1 | PIN1 | Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | chr19 | GO:0008013 | Not Cancer Driver | No | 17 | 0.104 | 115 | 12 | 0.104 | 0 |
PRKN | PRKN | O60260 | E3 ubiquitin-protein ligase parkin | chr6 | GO:0008013 | Not Cancer Driver | No | 110 | 0.237 | 78 | 15 | 0.192 | 31 |
PROP1 | PROP1 | O75360 | Homeobox protein prophet of Pit-1 | chr5 | GO:0008013 | Not Cancer Driver | No | 35 | 0.155 | 194 | 32 | 0.165 | 7 |
PSEN1 | PSEN1 | P49768 | Presenilin-1 | chr14 | GO:0008013 | Not Cancer Driver | No | 61 | 0.131 | 134 | 21 | 0.157 | 96 |
PTPRJ | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0008013 | Not Cancer Driver | No | 184 | 0.138 | 401 | 61 | 0.152 | 0 |
PTPRK_ENST00000368215 | PTPRK | Q15262 | Receptor-type tyrosine-protein phosphatase kappa | chr6 | GO:0008013 | Census, Compendium | Yes | 292 | 0.203 | 302 | 57 | 0.189 | 0 |
PTPRT_ENST00000373187 | PTPRT | O14522 | Receptor-type tyrosine-protein phosphatase T | chr20 | GO:0008013 | Census, Compendium | Yes | 535 | 0.371 | 299 | 125 | 0.418 | 0 |
PTPRU | PTPRU | Q92729 | Receptor-type tyrosine-protein phosphatase U | chr1 | GO:0008013 | Not Cancer Driver | No | 248 | 0.172 | 325 | 64 | 0.197 | 0 |
PXN_ENST00000228307 | PXN | P49023 | Paxillin | chr12 | GO:0008013 | Not Cancer Driver | No | 62 | 0.105 | 341 | 24 | 0.07 | 0 |
RORA_ENST00000335670 | RORA | P35398 | Nuclear receptor ROR-alpha | chr15 | GO:0008013 | Not Cancer Driver | No | 57 | 0.109 | 182 | 17 | 0.093 | 4 |
RUVBL2 | RUVBL2 | Q9Y230 | RuvB-like 2 | chr19 | GO:0008013 | Not Cancer Driver | No | 62 | 0.134 | 100 | 13 | 0.13 | 0 |
SALL1 | SALL1 | Q9NSC2 | Sal-like protein 1 | chr16 | GO:0008013 | Not Cancer Driver | No | 454 | 0.343 | 949 | 334 | 0.352 | 0 |
SETD1A | SETD1A | O15047 | Histone-lysine N-methyltransferase SETD1A | chr16 | GO:0008013 | Not Cancer Driver | No | 223 | 0.131 | 1327 | 188 | 0.142 | 5 |
SHROOM2 | SHROOM2 | Q13796 | Protein Shroom2 | chrX | GO:0008013 | Not Cancer Driver | No | 215 | 0.133 | 1381 | 188 | 0.136 | 0 |
SKP1_ENST00000517625 | SKP1 | P63208 | S-phase kinase-associated protein 1 | chr5 | GO:0008013 | Not Cancer Driver | No | 19 | 0.117 | 95 | 17 | 0.179 | 0 |
SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0008013 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
SLC9A3R2 | SLC9A3R2 | Q15599 | Na(+)/H(+) exchange regulatory cofactor NHE-RF2 | chr16 | GO:0008013 | Not Cancer Driver | No | 26 | 0.077 | 328 | 26 | 0.079 | 0 |
SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0008013 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
SMAD7 | SMAD7 | O15105 | Mothers against decapentaplegic homolog 7 | chr18 | GO:0008013 | Not Cancer Driver | No | 40 | 0.094 | 139 | 0 | 0.0 | 0 |
SOX17 | SOX17 | Q9H6I2 | Transcription factor SOX-17 | chr8 | GO:0008013 | Compendium | Yes | 81 | 0.196 | 378 | 59 | 0.156 | 2 |
SOX30 | SOX30 | O94993 | Transcription factor SOX-30 | chr5 | GO:0008013 | Not Cancer Driver | No | 103 | 0.137 | 659 | 89 | 0.135 | 0 |
SOX9 | SOX9 | P48436 | Transcription factor SOX-9 | chr17 | GO:0008013 | Compendium | Yes | 86 | 0.169 | 495 | 82 | 0.166 | 18 |
SUFU | SUFU | Q9UMX1 | Suppressor of fused homolog | chr10 | GO:0008013 | Census | Yes | 55 | 0.114 | 199 | 19 | 0.095 | 2 |
TAX1BP3 | TAX1BP3 | O14907 | Tax1-binding protein 3 | chr17 | GO:0008013 | Not Cancer Driver | No | 16 | 0.129 | 51 | 8 | 0.157 | 0 |
TBL1X | TBL1X | O60907 | F-box-like/WD repeat-containing protein TBL1X | chrX | GO:0008013 | Not Cancer Driver | No | 85 | 0.147 | 181 | 35 | 0.193 | 0 |
TBL1XR1 | TBL1XR1 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | chr3 | GO:0008013 | Census, Compendium | Yes | 82 | 0.16 | 136 | 19 | 0.14 | 4 |
TCF4_ENST00000564999 | TCF4 | P15884 | Transcription factor 4 | chr18 | GO:0008013 | Compendium | Yes | 141 | 0.211 | 662 | 136 | 0.205 | 13 |
TCF7L1 | TCF7L1 | Q9HCS4 | Transcription factor 7-like 1 | chr2 | GO:0008013 | Not Cancer Driver | No | 54 | 0.092 | 552 | 51 | 0.092 | 0 |
TCF7L2_ENST00000355995 | TCF7L2 | Q9NQB0 | Transcription factor 7-like 2 | chr10 | GO:0008013 | Census, Compendium | Yes | 122 | 0.197 | 516 | 93 | 0.18 | 0 |
TRPC4_ENST00000379705 | TRPC4 | Q9UBN4 | Short transient receptor potential channel 4 | chr13 | GO:0008013 | Not Cancer Driver | No | 322 | 0.33 | 195 | 66 | 0.338 | 0 |
VCL | VCL | P18206 | Vinculin | chr10 | GO:0008013 | Not Cancer Driver | No | 114 | 0.101 | 673 | 80 | 0.119 | 2 |