Total number of protein in "GO:0007623" GO term: 84
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AANAT_ENST00000392492 | AANAT | Q16613 | Serotonin N-acetyltransferase | chr17 | GO:0007623 | Not Cancer Driver | No | 22 | 0.106 | 28 | 4 | 0.143 | 0 |
| ADCY1 | ADCY1 | Q08828 | Adenylate cyclase type 1 | chr7 | GO:0007623 | Not Cancer Driver | No | 244 | 0.218 | 99 | 19 | 0.192 | 0 |
| ADIPOQ | ADIPOQ | Q15848 | Adiponectin | chr3 | GO:0007623 | Not Cancer Driver | No | 39 | 0.16 | 92 | 21 | 0.228 | 1 |
| AGRP | AGRP | O00253 | Agouti-related protein | chr16 | GO:0007623 | Not Cancer Driver | No | 13 | 0.098 | 32 | 4 | 0.125 | 0 |
| ARNTL | ARNTL | O00327 | Aryl hydrocarbon receptor nuclear translocator-like protein 1 | chr11 | GO:0007623 | Not Cancer Driver | No | 71 | 0.113 | 332 | 40 | 0.12 | 0 |
| ARNTL2 | ARNTL2 | Q8WYA1 | Aryl hydrocarbon receptor nuclear translocator-like protein 2 | chr12 | GO:0007623 | Not Cancer Driver | No | 79 | 0.124 | 264 | 38 | 0.144 | 0 |
| ASS1_ENST00000352480 | ASS1 | P00966 | Argininosuccinate synthase | chr9 | GO:0007623 | Not Cancer Driver | No | 65 | 0.158 | 63 | 8 | 0.127 | 86 |
| ATF5_ENST00000595125 | ATF5 | Q9Y2D1 | Cyclic AMP-dependent transcription factor ATF-5 | chr19 | GO:0007623 | Not Cancer Driver | No | 47 | 0.167 | 239 | 40 | 0.167 | 0 |
| ATOH7 | ATOH7 | Q8N100 | Transcription factor ATOH7 | chr10 | GO:0007623 | Not Cancer Driver | No | 10 | 0.066 | 40 | 3 | 0.075 | 2 |
| BHLHE40 | BHLHE40 | O14503 | Class E basic helix-loop-helix protein 40 | chr3 | GO:0007623 | Not Cancer Driver | No | 52 | 0.126 | 242 | 31 | 0.128 | 0 |
| BLOC1S6_ENST00000220531 | BLOC1S6 | Q9UL45 | Biogenesis of lysosome-related organelles complex 1 subunit 6 | chr15 | GO:0007623 | Not Cancer Driver | No | 12 | 0.07 | 111 | 11 | 0.099 | 0 |
| BTBD9 | BTBD9 | Q96Q07 | BTB/POZ domain-containing protein 9 | chr6 | GO:0007623 | Not Cancer Driver | No | 84 | 0.137 | 66 | 6 | 0.091 | 0 |
| C3orf70 | C3orf70 | A6NLC5 | UPF0524 protein C3orf70 | chr3 | GO:0007623 | Not Cancer Driver | No | 57 | 0.228 | 138 | 43 | 0.312 | 0 |
| CIART | CIART | Q8N365 | Circadian-associated transcriptional repressor | chr1 | GO:0007623 | Not Cancer Driver | No | 59 | 0.153 | 272 | 40 | 0.147 | 0 |
| CLDN4 | CLDN4 | O14493 | Claudin-4 | chr7 | GO:0007623 | Not Cancer Driver | No | 40 | 0.191 | 0 | 0 | 0.0 | 0 |
| CLOCK | CLOCK | O15516 | Circadian locomoter output cycles protein kaput | chr4 | GO:0007623 | Not Cancer Driver | No | 83 | 0.098 | 458 | 38 | 0.083 | 0 |
| CREB1_ENST00000430624 | CREB1 | P16220 | Cyclic AMP-responsive element-binding protein 1 | chr2 | GO:0007623 | Census | Yes | 25 | 0.076 | 277 | 23 | 0.083 | 0 |
| CRY1 | CRY1 | Q16526 | Cryptochrome-1 | chr12 | GO:0007623 | Not Cancer Driver | No | 76 | 0.13 | 91 | 5 | 0.055 | 0 |
| CRY2_ENST00000616080 | CRY2 | Q49AN0 | Cryptochrome-2 | chr11 | GO:0007623 | Not Cancer Driver | No | 72 | 0.121 | 100 | 12 | 0.12 | 0 |
| DBP | DBP | Q10586 | D site-binding protein | chr19 | GO:0007623 | Not Cancer Driver | No | 24 | 0.074 | 280 | 18 | 0.064 | 0 |
| DDC | DDC | P20711 | Aromatic-L-amino-acid decarboxylase | chr7 | GO:0007623 | Not Cancer Driver | No | 98 | 0.204 | 5 | 0 | 0.0 | 9 |
| DYRK1A_ENST00000644942 | DYRK1A | Q13627 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | chr21 | GO:0007623 | Not Cancer Driver | No | 135 | 0.177 | 447 | 73 | 0.163 | 0 |
| EGR1 | EGR1 | P18146 | Early growth response protein 1 | chr5 | GO:0007623 | Not Cancer Driver | No | 78 | 0.144 | 501 | 72 | 0.144 | 0 |
| EGR3 | EGR3 | Q06889 | Early growth response protein 3 | chr8 | GO:0007623 | Not Cancer Driver | No | 60 | 0.155 | 252 | 46 | 0.183 | 0 |
| EP300 | EP300 | Q09472 | Histone acetyltransferase p300 | chr22 | GO:0007623 | Census, Compendium | Yes | 334 | 0.138 | 1790 | 196 | 0.109 | 1 |
| F7 | F7 | P08709 | Coagulation factor VII | chr13 | GO:0007623 | Not Cancer Driver | No | 74 | 0.159 | 50 | 7 | 0.14 | 108 |
| GPR157 | GPR157 | Q5UAW9 | G-protein coupled receptor 157 | chr1 | GO:0007623 | Not Cancer Driver | No | 37 | 0.11 | 38 | 6 | 0.158 | 0 |
| GPR176 | GPR176 | Q14439 | G-protein coupled receptor 176 | chr15 | GO:0007623 | Not Cancer Driver | No | 63 | 0.122 | 124 | 17 | 0.137 | 0 |
| GSK3B_ENST00000264235 | GSK3B | P49841 | Glycogen synthase kinase-3 beta | chr3 | GO:0007623 | Not Cancer Driver | No | 56 | 0.133 | 146 | 13 | 0.089 | 0 |
| HCRTR2 | HCRTR2 | O43614 | Orexin receptor type 2 | chr6 | GO:0007623 | Not Cancer Driver | No | 154 | 0.347 | 38 | 13 | 0.342 | 0 |
| HEBP1 | HEBP1 | Q9NRV9 | Heme-binding protein 1 | chr12 | GO:0007623 | Not Cancer Driver | No | 18 | 0.095 | 53 | 3 | 0.057 | 0 |
| HNRNPD | HNRNPD | Q14103 | Heterogeneous nuclear ribonucleoprotein D0 | chr4 | GO:0007623 | Not Cancer Driver | No | 39 | 0.11 | 206 | 19 | 0.092 | 0 |
| HOMER1 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | GO:0007623 | Not Cancer Driver | No | 46 | 0.13 | 243 | 32 | 0.132 | 0 |
| HTR7 | HTR7 | P34969 | 5-hydroxytryptamine receptor 7 | chr10 | GO:0007623 | Not Cancer Driver | No | 102 | 0.213 | 24 | 1 | 0.042 | 0 |
| ID2_ENST00000396290 | ID2 | Q02363 | DNA-binding protein inhibitor ID-2 | chr2 | GO:0007623 | Not Cancer Driver | No | 14 | 0.104 | 52 | 7 | 0.135 | 0 |
| IMPDH2 | IMPDH2 | P12268 | Inosine-5'-monophosphate dehydrogenase 2 | chr3 | GO:0007623 | Not Cancer Driver | No | 70 | 0.136 | 6 | 1 | 0.167 | 0 |
| JUND | JUND | P17535 | Transcription factor JunD | chr19 | GO:0007623 | Not Cancer Driver | No | 21 | 0.061 | 313 | 19 | 0.061 | 0 |
| KCND2 | KCND2 | Q9NZV8 | Potassium voltage-gated channel subfamily D member 2 | chr7 | GO:0007623 | Not Cancer Driver | No | 220 | 0.349 | 195 | 62 | 0.318 | 0 |
| KCNH7 | KCNH7 | Q9NS40 | Potassium voltage-gated channel subfamily H member 7 | chr2 | GO:0007623 | Not Cancer Driver | No | 324 | 0.271 | 508 | 138 | 0.272 | 0 |
| KLF10 | KLF10 | Q13118 | Krueppel-like factor 10 | chr8 | GO:0007623 | Not Cancer Driver | No | 59 | 0.123 | 349 | 46 | 0.132 | 0 |
| KLF9 | KLF9 | Q13886 | Krueppel-like factor 9 | chr9 | GO:0007623 | Not Cancer Driver | No | 34 | 0.139 | 154 | 24 | 0.156 | 0 |
| LEP | LEP | P41159 | Leptin | chr7 | GO:0007623 | Not Cancer Driver | No | 29 | 0.174 | 0 | 0 | 0.0 | 2 |
| MC3R | MC3R | P41968 | Melanocortin receptor 3 | chr20 | GO:0007623 | Not Cancer Driver | No | 96 | 0.297 | 0 | 0 | 0.0 | 0 |
| METTL3 | METTL3 | Q86U44 | N6-adenosine-methyltransferase catalytic subunit | chr14 | GO:0007623 | Not Cancer Driver | No | 74 | 0.128 | 274 | 29 | 0.106 | 0 |
| MTA1 | MTA1 | Q13330 | Metastasis-associated protein MTA1 | chr14 | GO:0007623 | Not Cancer Driver | No | 92 | 0.129 | 327 | 42 | 0.128 | 0 |
| MTNR1A | MTNR1A | P48039 | Melatonin receptor type 1A | chr4 | GO:0007623 | Not Cancer Driver | No | 72 | 0.206 | 0 | 0 | 0.0 | 0 |
| MTTP_ENST00000265517 | MTTP | P55157 | Microsomal triglyceride transfer protein large subunit | chr4 | GO:0007623 | Not Cancer Driver | No | 165 | 0.185 | 47 | 11 | 0.234 | 8 |
| NAGLU | NAGLU | P54802 | Alpha-N-acetylglucosaminidase | chr17 | GO:0007623 | Not Cancer Driver | No | 70 | 0.094 | 18 | 1 | 0.056 | 68 |
| NCOA2 | NCOA2 | Q15596 | Nuclear receptor coactivator 2 | chr8 | GO:0007623 | Census, Compendium | Yes | 210 | 0.143 | 1281 | 185 | 0.144 | 0 |
| NCOR1 | NCOR1 | O75376 | Nuclear receptor corepressor 1 | chr17 | GO:0007623 | Census, Compendium | Yes | 352 | 0.144 | 2347 | 340 | 0.145 | 0 |
| NDUFA9 | NDUFA9 | Q16795 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial | chr12 | GO:0007623 | Not Cancer Driver | No | 57 | 0.151 | 8 | 0 | 0.0 | 2 |
| NFIL3 | NFIL3 | Q16649 | Nuclear factor interleukin-3-regulated protein | chr9 | GO:0007623 | Not Cancer Driver | No | 57 | 0.123 | 333 | 41 | 0.123 | 0 |
| NMS | NMS | Q5H8A3 | Neuromedin-S | chr2 | GO:0007623 | Not Cancer Driver | No | 41 | 0.268 | 21 | 7 | 0.333 | 0 |
| NONO | NONO | Q15233 | Non-POU domain-containing octamer-binding protein | chrX | GO:0007623 | Census, Compendium | Yes | 101 | 0.214 | 349 | 64 | 0.183 | 0 |
| NOS2 | NOS2 | P35228 | Nitric oxide synthase, inducible | chr17 | GO:0007623 | Not Cancer Driver | No | 207 | 0.18 | 201 | 33 | 0.164 | 0 |
| NR0B2 | NR0B2 | Q15466 | Nuclear receptor subfamily 0 group B member 2 | chr1 | GO:0007623 | Not Cancer Driver | No | 35 | 0.136 | 10 | 2 | 0.2 | 0 |
| NR1D1 | NR1D1 | P20393 | Nuclear receptor subfamily 1 group D member 1 | chr17 | GO:0007623 | Not Cancer Driver | No | 81 | 0.132 | 348 | 49 | 0.141 | 0 |
| NR1D2 | NR1D2 | Q14995 | Nuclear receptor subfamily 1 group D member 2 | chr3 | GO:0007623 | Not Cancer Driver | No | 76 | 0.131 | 223 | 25 | 0.112 | 0 |
| NRIP1_ENST00000400199 | NRIP1 | P48552 | Nuclear receptor-interacting protein 1 | chr21 | GO:0007623 | Not Cancer Driver | No | 141 | 0.122 | 998 | 124 | 0.124 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0007623 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
| NTRK2_ENST00000323115 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0007623 | Not Cancer Driver | No | 155 | 0.189 | 117 | 18 | 0.154 | 1 |
| PER1 | PER1 | O15534 | Period circadian protein homolog 1 | chr17 | GO:0007623 | Census | Yes | 160 | 0.124 | 948 | 116 | 0.122 | 0 |
| PER2 | PER2 | O15055 | Period circadian protein homolog 2 | chr2 | GO:0007623 | Not Cancer Driver | No | 166 | 0.132 | 782 | 101 | 0.129 | 1 |
| PROK2 | PROK2 | Q9HC23 | Prokineticin-2 | chr3 | GO:0007623 | Not Cancer Driver | No | 18 | 0.14 | 23 | 1 | 0.043 | 6 |
| PROKR2 | PROKR2 | Q8NFJ6 | Prokineticin receptor 2 | chr20 | GO:0007623 | Not Cancer Driver | No | 131 | 0.341 | 13 | 2 | 0.154 | 16 |
| PROX1 | PROX1 | Q92786 | Prospero homeobox protein 1 | chr1 | GO:0007623 | Not Cancer Driver | No | 182 | 0.247 | 537 | 141 | 0.263 | 0 |
| PTEN | PTEN | P60484 | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | chr10 | GO:0007623 | Census, Compendium | Yes | 505 | 1.253 | 76 | 4 | 0.053 | 41 |
| RBM4B_ENST00000310046 | RBM4B | Q9BQ04 | RNA-binding protein 4B | chr11 | GO:0007623 | Not Cancer Driver | No | 47 | 0.131 | 126 | 19 | 0.151 | 0 |
| RBM4_ENST00000310092 | RBM4 | Q9BWF3 | RNA-binding protein 4 | chr11 | GO:0007623 | Not Cancer Driver | No | 40 | 0.11 | 129 | 12 | 0.093 | 0 |
| RPE65 | RPE65 | Q16518 | Retinoid isomerohydrolase | chr1 | GO:0007623 | Not Cancer Driver | No | 109 | 0.205 | 10 | 1 | 0.1 | 44 |
| SETX | SETX | Q7Z333 | Probable helicase senataxin | chr9 | GO:0007623 | Not Cancer Driver | No | 342 | 0.128 | 1240 | 156 | 0.126 | 20 |
| SLC6A4_ENST00000401766 | SLC6A4 | P31645 | Sodium-dependent serotonin transporter | chr17 | GO:0007623 | Not Cancer Driver | No | 101 | 0.16 | 73 | 12 | 0.164 | 0 |
| SRD5A1 | SRD5A1 | P18405 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1 | chr5 | GO:0007623 | Not Cancer Driver | No | 35 | 0.135 | 0 | 0 | 0.0 | 0 |
| SREBF1_ENST00000261646 | SREBF1 | P36956 | Sterol regulatory element-binding protein 1 | chr17 | GO:0007623 | Not Cancer Driver | No | 127 | 0.111 | 528 | 64 | 0.121 | 4 |
| TH | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0007623 | Not Cancer Driver | No | 61 | 0.116 | 149 | 21 | 0.141 | 38 |
| THRAP3_ENST00000469141 | THRAP3 | Q9Y2W1 | Thyroid hormone receptor-associated protein 3 | chr1 | GO:0007623 | Census | Yes | 137 | 0.143 | 955 | 137 | 0.143 | 0 |
| TIMELESS | TIMELESS | Q9UNS1 | Protein timeless homolog | chr12 | GO:0007623 | Not Cancer Driver | No | 154 | 0.127 | 367 | 51 | 0.139 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0007623 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFRSF11A | TNFRSF11A | Q9Y6Q6 | Tumor necrosis factor receptor superfamily member 11A | chr18 | GO:0007623 | Not Cancer Driver | No | 70 | 0.114 | 285 | 33 | 0.116 | 0 |
| TOP1 | TOP1 | P11387 | DNA topoisomerase 1 | chr20 | GO:0007623 | Census, Compendium | Yes | 93 | 0.122 | 391 | 53 | 0.136 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0007623 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TPH2 | TPH2 | Q8IWU9 | Tryptophan 5-hydroxylase 2 | chr12 | GO:0007623 | Not Cancer Driver | No | 118 | 0.241 | 55 | 17 | 0.309 | 1 |
| TYMS | TYMS | P04818 | Thymidylate synthase | chr18 | GO:0007623 | Not Cancer Driver | No | 22 | 0.07 | 41 | 0 | 0.0 | 0 |
| USP2 | USP2 | O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | chr11 | GO:0007623 | Not Cancer Driver | No | 88 | 0.145 | 213 | 39 | 0.183 | 0 |