Filter in search result
Please select a valid state.

Total number of protein in "GO:0007610" GO term:  550

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AAAS AAAS Q9NRG9 Aladin chr12 GO:0007610 Not Cancer Driver No 58 0.106 116 12 0.103 3
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0007610 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA2_ENST00000371605 ABCA2 Q9BZC7 ATP-binding cassette sub-family A member 2 chr9 GO:0007610 Not Cancer Driver No 240 0.099 497 44 0.089 0
ABCA7 ABCA7 Q8IZY2 Phospholipid-transporting ATPase ABCA7 chr19 GO:0007610 Not Cancer Driver No 260 0.121 402 35 0.087 1
ABCC8_ENST00000389817 ABCC8 Q09428 ATP-binding cassette sub-family C member 8 chr11 GO:0007610 Not Cancer Driver No 255 0.161 138 23 0.167 97
ABHD12_ENST00000339157 ABHD12 Q8N2K0 Lysophosphatidylserine lipase ABHD12 chr20 GO:0007610 Not Cancer Driver No 45 0.113 8 1 0.125 1
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0007610 Census, Compendium Yes 139 0.123 604 73 0.121 2
ABL2 ABL2 P42684 Tyrosine-protein kinase ABL2 chr1 GO:0007610 Census, Compendium Yes 171 0.145 641 70 0.109 0
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0007610 Not Cancer Driver No 201 0.154 86 8 0.093 0
ACE2 ACE2 Q9BYF1 Angiotensin-converting enzyme 2 chrX GO:0007610 Not Cancer Driver No 104 0.129 68 5 0.074 0
ACTR2_ENST00000260641 ACTR2 P61160 Actin-related protein 2 chr2 GO:0007610 Not Cancer Driver No 51 0.129 6 2 0.333 0
ADAM2 ADAM2 Q99965 Disintegrin and metalloproteinase domain-containing protein 2 chr8 GO:0007610 Not Cancer Driver No 194 0.264 18 4 0.222 0
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0007610 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0007610 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADCY3_ENST00000260600 ADCY3 O60266 Adenylate cyclase type 3 chr2 GO:0007610 Not Cancer Driver No 135 0.118 185 18 0.097 0
ADCY5 ADCY5 O95622 Adenylate cyclase type 5 chr3 GO:0007610 Not Cancer Driver No 234 0.186 268 23 0.086 2
ADCY8 ADCY8 P40145 Adenylate cyclase type 8 chr8 GO:0007610 Not Cancer Driver No 419 0.335 215 38 0.177 0
ADGRB3_ENST00000546190 ADGRB3 O60242 Adhesion G protein-coupled receptor B3 chr6 GO:0007610 Not Cancer Driver No 558 0.367 336 149 0.443 0
ADGRF1 ADGRF1 Q5T601 Adhesion G-protein coupled receptor F1 chr6 GO:0007610 Not Cancer Driver No 159 0.175 8 0 0.0 0
ADM2_ENST00000395737 ADM2 Q7Z4H4 Protein ADM2 chr22 GO:0007610 Not Cancer Driver No 14 0.095 113 11 0.097 0
ADNP ADNP Q9H2P0 Activity-dependent neuroprotector homeobox protein chr20 GO:0007610 Not Cancer Driver No 130 0.118 615 66 0.107 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0007610 Not Cancer Driver No 61 0.148 93 11 0.118 0
AFF2 AFF2 P51816 AF4/FMR2 family member 2 chrX GO:0007610 Not Cancer Driver No 409 0.312 1003 314 0.313 0
AGER_ENST00000375076 AGER Q15109 Advanced glycosylation end product-specific receptor chr6 GO:0007610 Not Cancer Driver No 31 0.077 297 21 0.071 0
AGRP AGRP O00253 Agouti-related protein chr16 GO:0007610 Not Cancer Driver No 13 0.098 32 4 0.125 0
AGT AGT P01019 Angiotensinogen chr1 GO:0007610 Not Cancer Driver No 85 0.179 33 10 0.303 1
AGTPBP1_ENST00000357081 AGTPBP1 Q9UPW5 Cytosolic carboxypeptidase 1 chr9 GO:0007610 Not Cancer Driver No 158 0.129 321 42 0.131 4
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0007610 Not Cancer Driver No 98 0.27 0 0 0.0 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0007610 Census, Compendium Yes 108 0.225 158 24 0.152 4
ALDH1A3 ALDH1A3 P47895 Aldehyde dehydrogenase family 1 member A3 chr15 GO:0007610 Not Cancer Driver No 74 0.145 73 7 0.096 10
ALK ALK Q9UM73 ALK tyrosine kinase receptor chr2 GO:0007610 Census, Compendium Yes 303 0.187 575 114 0.198 16
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0007610 Not Cancer Driver No 194 0.117 353 36 0.102 0
AMFR AMFR Q9UKV5 E3 ubiquitin-protein ligase AMFR chr16 GO:0007610 Not Cancer Driver No 73 0.114 229 30 0.131 0
ANKH ANKH Q9HCJ1 Progressive ankylosis protein homolog chr5 GO:0007610 Not Cancer Driver No 76 0.154 34 5 0.147 6
APBA1 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 GO:0007610 Not Cancer Driver No 149 0.178 556 103 0.185 0
APLN APLN Q9ULZ1 Apelin chrX GO:0007610 Not Cancer Driver No 8 0.104 51 6 0.118 0
APOE APOE P02649 Apolipoprotein E chr19 GO:0007610 Not Cancer Driver No 25 0.079 124 6 0.048 12
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0007610 Not Cancer Driver No 128 0.166 418 71 0.17 17
APRT APRT P07741 Adenine phosphoribosyltransferase chr16 GO:0007610 Not Cancer Driver No 16 0.089 0 0 0.0 8
ARC ARC Q7LC44 Activity-regulated cytoskeleton-associated protein chr8 GO:0007610 Not Cancer Driver No 64 0.162 194 29 0.149 0
ARCN1 ARCN1 P48444 Coatomer subunit delta chr11 GO:0007610 Not Cancer Driver No 46 0.09 194 24 0.124 0
ARF4 ARF4 P18085 ADP-ribosylation factor 4 chr3 GO:0007610 Not Cancer Driver No 17 0.094 0 0 0.0 0
ARL6IP5 ARL6IP5 O75915 PRA1 family protein 3 chr3 GO:0007610 Not Cancer Driver No 26 0.138 0 0 0.0 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0007610 Not Cancer Driver No 46 0.112 122 22 0.18 0
ASIC1_ENST00000447966 ASIC1 P78348 Acid-sensing ion channel 1 chr12 GO:0007610 Not Cancer Driver No 69 0.131 17 2 0.118 0
ASIP_ENST00000374954 ASIP P42127 Agouti-signaling protein chr20 GO:0007610 Not Cancer Driver No 16 0.121 36 9 0.25 0
ASTN1 ASTN1 O14525 Astrotactin-1 chr1 GO:0007610 Not Cancer Driver No 466 0.358 285 114 0.4 0
ATAD1_ENST00000328142 ATAD1 Q8NBU5 Outer mitochondrial transmembrane helix translocase chr10 GO:0007610 Not Cancer Driver No 32 0.089 71 3 0.042 0
ATP1A2 ATP1A2 P50993 Sodium/potassium-transporting ATPase subunit alpha-2 chr1 GO:0007610 Not Cancer Driver No 230 0.225 161 34 0.211 8
ATP1B2 ATP1B2 P14415 Sodium/potassium-transporting ATPase subunit beta-2 chr17 GO:0007610 Not Cancer Driver No 40 0.138 16 6 0.375 0
ATP6V1B1 ATP6V1B1 P15313 V-type proton ATPase subunit B, kidney isoform chr2 GO:0007610 Not Cancer Driver No 77 0.15 66 14 0.212 9
ATP7A ATP7A Q04656 Copper-transporting ATPase 1 chrX GO:0007610 Not Cancer Driver No 228 0.152 171 46 0.269 52
ATP8A1 ATP8A1 Q9Y2Q0 Phospholipid-transporting ATPase IA chr4 GO:0007610 Not Cancer Driver No 185 0.159 84 7 0.083 0
ATP8A2 ATP8A2 Q9NTI2 Phospholipid-transporting ATPase IB chr13 GO:0007610 Not Cancer Driver No 236 0.199 78 14 0.179 1
ATXN1 ATXN1 P54253 Ataxin-1 chr6 GO:0007610 Not Cancer Driver No 193 0.237 604 168 0.278 0
ATXN1L ATXN1L P0C7T5 Ataxin-1-like chr16 GO:0007610 Not Cancer Driver No 30 0.044 476 19 0.04 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0007610 Not Cancer Driver No 14 0.085 26 0 0.0 39
AVPR1A AVPR1A P37288 Vasopressin V1a receptor chr12 GO:0007610 Not Cancer Driver No 105 0.251 68 25 0.368 0
B2M B2M P61769 Beta-2-microglobulin chr15 GO:0007610 Census, Compendium Yes 34 0.286 5 1 0.2 2
B4GALT2_ENST00000372324 B4GALT2 O60909 Beta-1,4-galactosyltransferase 2 chr1 GO:0007610 Not Cancer Driver No 53 0.142 105 14 0.133 0
BBS12 BBS12 Q6ZW61 Bardet-Biedl syndrome 12 protein chr4 GO:0007610 Not Cancer Driver No 88 0.124 34 5 0.147 10
BBS2 BBS2 Q9BXC9 Bardet-Biedl syndrome 2 protein chr16 GO:0007610 Not Cancer Driver No 90 0.125 76 16 0.211 20
BBS4 BBS4 Q96RK4 Bardet-Biedl syndrome 4 protein chr15 GO:0007610 Not Cancer Driver No 58 0.112 110 16 0.145 9
BCHE BCHE P06276 Cholinesterase chr3 GO:0007610 Not Cancer Driver No 185 0.307 14 4 0.286 38
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0007610 Census, Compendium Yes 24 0.1 72 5 0.069 0
BDNF_ENST00000439476 BDNF P23560 Brain-derived neurotrophic factor chr11 GO:0007610 Not Cancer Driver No 47 0.19 79 19 0.241 1
BHLHB9 BHLHB9 Q6PI77 Protein BHLHb9 chrX GO:0007610 Not Cancer Driver No 88 0.161 267 38 0.142 0
BLOC1S6_ENST00000220531 BLOC1S6 Q9UL45 Biogenesis of lysosome-related organelles complex 1 subunit 6 chr15 GO:0007610 Not Cancer Driver No 12 0.07 111 11 0.099 0
BRINP1 BRINP1 O60477 BMP/retinoic acid-inducible neural-specific protein 1 chr9 GO:0007610 Not Cancer Driver No 273 0.359 36 17 0.472 0
BRS3 BRS3 P32247 Bombesin receptor subtype-3 chrX GO:0007610 Not Cancer Driver No 72 0.18 32 8 0.25 0
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0007610 Not Cancer Driver No 131 0.168 459 78 0.17 0
BSX BSX Q3C1V8 Brain-specific homeobox protein homolog chr11 GO:0007610 Not Cancer Driver No 46 0.197 184 42 0.228 0
BTBD9 BTBD9 Q96Q07 BTB/POZ domain-containing protein 9 chr6 GO:0007610 Not Cancer Driver No 84 0.137 66 6 0.091 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0007610 Census Yes 32 0.203 7 2 0.286 0
C12orf10 MYG1 Q9HB07 MYG1 exonuclease chr12 GO:0007610 Not Cancer Driver No 30 0.08 95 9 0.095 0
C12orf57 C12orf57 Q99622 Protein C10 chr12 GO:0007610 Not Cancer Driver No 13 0.103 29 1 0.034 1
C1QL1 C1QL1 O75973 C1q-related factor chr17 GO:0007610 Not Cancer Driver No 25 0.097 126 5 0.04 0
C3orf70 C3orf70 A6NLC5 UPF0524 protein C3orf70 chr3 GO:0007610 Not Cancer Driver No 57 0.228 138 43 0.312 0
CALB1 CALB1 P05937 Calbindin chr8 GO:0007610 Not Cancer Driver No 46 0.176 0 0 0.0 0
CAMK2N1 CAMK2N1 Q7Z7J9 Calcium/calmodulin-dependent protein kinase II inhibitor 1 chr1 GO:0007610 Not Cancer Driver No 10 0.128 72 9 0.125 0
CAMK4_ENST00000512453 CAMK4 Q16566 Calcium/calmodulin-dependent protein kinase type IV chr5 GO:0007610 Not Cancer Driver No 101 0.214 127 30 0.236 0
CAPN2 CAPN2 P17655 Calpain-2 catalytic subunit chr1 GO:0007610 Not Cancer Driver No 81 0.116 46 11 0.239 0
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0007610 Not Cancer Driver No 18 0.155 0 0 0.0 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0007610 Census Yes 32 0.116 62 5 0.081 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0007610 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCK CCK P06307 Cholecystokinin chr3 GO:0007610 Not Cancer Driver No 27 0.235 68 14 0.206 0
CCL11 CCL11 P51671 Eotaxin chr17 GO:0007610 Not Cancer Driver No 18 0.186 14 3 0.214 0
CDH23_ENST00000224721 CDH23 Q9H251 Cadherin-23 chr10 GO:0007610 Not Cancer Driver No 541 0.161 674 93 0.138 58
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0007610 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEBPB CEBPB P17676 CCAAT/enhancer-binding protein beta chr20 GO:0007610 Not Cancer Driver No 3 0.009 276 2 0.007 0
CEND1 CEND1 Q8N111 Cell cycle exit and neuronal differentiation protein 1 chr11 GO:0007610 Not Cancer Driver No 13 0.087 124 10 0.081 0
CFAP69 CFAP69 A5D8W1 Cilia- and flagella-associated protein 69 chr7 GO:0007610 Not Cancer Driver No 127 0.135 100 19 0.19 0
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0007610 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0007610 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CHL1_ENST00000397491 CHL1 O00533 Neural cell adhesion molecule L1-like protein chr3 GO:0007610 Not Cancer Driver No 348 0.288 415 121 0.292 0
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0007610 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 GO:0007610 Not Cancer Driver No 144 0.23 186 33 0.177 2
CHRNA5 CHRNA5 P30532 Neuronal acetylcholine receptor subunit alpha-5 chr15 GO:0007610 Not Cancer Driver No 63 0.135 24 3 0.125 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0007610 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHRNB1 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 GO:0007610 Not Cancer Driver No 62 0.124 45 9 0.2 3
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0007610 Not Cancer Driver No 92 0.183 23 2 0.087 2
CHRNB4 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 GO:0007610 Not Cancer Driver No 98 0.197 30 6 0.2 0
CHST10_ENST00000409701 CHST10 O43529 Carbohydrate sulfotransferase 10 chr2 GO:0007610 Not Cancer Driver No 59 0.166 15 1 0.067 0
CIART CIART Q8N365 Circadian-associated transcriptional repressor chr1 GO:0007610 Not Cancer Driver No 59 0.153 272 40 0.147 0
CIC CIC Q96RK0 Protein capicua homolog chr19 GO:0007610 Census, Compendium Yes 276 0.172 1550 266 0.172 0
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0007610 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLDN5_ENST00000618236 CLDN5 O00501 Claudin-5 chr22 GO:0007610 Not Cancer Driver No 15 0.069 0 0 0.0 0
CLN3_ENST00000636147 CLN3 Q13286 Battenin chr16 GO:0007610 Not Cancer Driver No 58 0.132 69 10 0.145 9
CLN8 CLN8 Q9UBY8 Protein CLN8 chr8 GO:0007610 Not Cancer Driver No 45 0.157 16 2 0.125 16
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0007610 Not Cancer Driver No 36 0.086 71 2 0.028 0
CNR1_ENST00000549890 CNR1 P21554 Cannabinoid receptor 1 chr6 GO:0007610 Not Cancer Driver No 129 0.273 9 1 0.111 0
CNTFR_ENST00000351266 CNTFR P26992 Ciliary neurotrophic factor receptor subunit alpha chr9 GO:0007610 Not Cancer Driver No 50 0.134 92 8 0.087 0
CNTN1 CNTN1 Q12860 Contactin-1 chr12 GO:0007610 Not Cancer Driver No 265 0.26 220 50 0.227 0
CNTN2 CNTN2 Q02246 Contactin-2 chr1 GO:0007610 Not Cancer Driver No 155 0.149 370 61 0.165 0
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0007610 Census Yes 570 0.428 161 82 0.509 0
CPEB3_ENST00000265997 CPEB3 Q8NE35 Cytoplasmic polyadenylation element-binding protein 3 chr10 GO:0007610 Census, Compendium Yes 66 0.095 414 28 0.068 0
CPT1A_ENST00000539743 CPT1A P50416 Carnitine O-palmitoyltransferase 1, liver isoform chr11 GO:0007610 Not Cancer Driver No 144 0.186 62 10 0.161 15
CRBN CRBN Q96SW2 Protein cereblon chr3 GO:0007610 Not Cancer Driver No 52 0.118 76 10 0.132 1
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0007610 Census Yes 25 0.076 277 23 0.083 0
CRH CRH P06850 Corticoliberin chr8 GO:0007610 Not Cancer Driver No 10 0.051 131 9 0.069 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0007610 Not Cancer Driver No 61 0.189 0 0 0.0 0
CRTC1_ENST00000321949 CRTC1 Q6UUV9 CREB-regulated transcription coactivator 1 chr19 GO:0007610 Census, Compendium Yes 63 0.099 606 62 0.102 0
CSMD1 CSMD1 Q96PZ7 CUB and sushi domain-containing protein 1 chr8 GO:0007610 Not Cancer Driver No 1236 0.347 234 76 0.325 0
CSTB CSTB P04080 Cystatin-B chr21 GO:0007610 Not Cancer Driver No 7 0.071 40 0 0.0 1
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:0007610 Not Cancer Driver No 34 0.093 0 0 0.0 31
CUX2 CUX2 O14529 Homeobox protein cut-like 2 chr12 GO:0007610 Not Cancer Driver No 277 0.186 1201 212 0.177 1
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0007610 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0007610 Not Cancer Driver No 16 0.172 0 0 0.0 0
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0007610 Not Cancer Driver No 200 0.34 393 143 0.364 0
DACH1_ENST00000619232 DACH1 Q9UI36 Dachshund homolog 1 chr13 GO:0007610 Not Cancer Driver No 157 0.207 641 134 0.209 0
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0007610 Not Cancer Driver No 125 0.203 71 17 0.239 3
DCANP1 DCANP1 Q8TF63 Dendritic cell nuclear protein 1 chr5 GO:0007610 Not Cancer Driver No 44 0.18 159 35 0.22 0
DCTN1 DCTN1 Q14203 Dynactin subunit 1 chr2 GO:0007610 Census Yes 172 0.135 817 111 0.136 11
DDHD2_ENST00000520272 DDHD2 O94830 Phospholipase DDHD2 chr8 GO:0007610 Not Cancer Driver No 95 0.134 169 25 0.148 1
DERL2 DERL2 Q9GZP9 Derlin-2 chr17 GO:0007610 Not Cancer Driver No 19 0.079 15 1 0.067 0
DKK1 DKK1 O94907 Dickkopf-related protein 1 chr10 GO:0007610 Not Cancer Driver No 58 0.218 47 8 0.17 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0007610 Not Cancer Driver No 116 0.16 232 55 0.237 0
DMBX1_ENST00000371956 DMBX1 Q8NFW5 Diencephalon/mesencephalon homeobox protein 1 chr1 GO:0007610 Not Cancer Driver No 93 0.243 272 69 0.254 0
DMRT3 DMRT3 Q9NQL9 Doublesex- and mab-3-related transcription factor 3 chr9 GO:0007610 Not Cancer Driver No 94 0.199 345 71 0.206 0
DMRTA1 DMRTA1 Q5VZB9 Doublesex- and mab-3-related transcription factor A1 chr9 GO:0007610 Not Cancer Driver No 50 0.099 276 25 0.091 0
DNAH11 DNAH11 Q96DT5 Dynein axonemal heavy chain 11 chr7 GO:0007610 Not Cancer Driver No 885 0.196 221 36 0.163 3
DPP4 DPP4 P27487 Dipeptidyl peptidase 4 chr2 GO:0007610 Not Cancer Driver No 151 0.197 8 1 0.125 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0007610 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0007610 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0007610 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0007610 Not Cancer Driver No 26 0.062 109 0 0.0 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0007610 Not Cancer Driver No 172 0.361 29 18 0.621 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0007610 Not Cancer Driver No 652 0.324 603 201 0.333 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0007610 Not Cancer Driver No 49 0.14 210 25 0.119 0
DVL1 DVL1 O14640 Segment polarity protein dishevelled homolog DVL-1 chr1 GO:0007610 Not Cancer Driver No 73 0.105 434 38 0.088 0
DYNLRB1 DYNLRB1 Q9NP97 Dynein light chain roadblock-type 1 chr20 GO:0007610 Not Cancer Driver No 23 0.24 19 4 0.211 0
EFNB3 EFNB3 Q15768 Ephrin-B3 chr17 GO:0007610 Not Cancer Driver No 45 0.132 183 22 0.12 0
EGFR EGFR P00533 Epidermal growth factor receptor chr7 GO:0007610 Census, Compendium Yes 444 0.367 223 35 0.157 1
EGR1 EGR1 P18146 Early growth response protein 1 chr5 GO:0007610 Not Cancer Driver No 78 0.144 501 72 0.144 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0007610 Compendium Yes 90 0.189 352 59 0.168 11
EHMT2_ENST00000375537 EHMT2 Q96KQ7 Histone-lysine N-methyltransferase EHMT2 chr6 GO:0007610 Not Cancer Driver No 142 0.117 585 71 0.121 0
EIF2AK4 EIF2AK4 Q9P2K8 eIF-2-alpha kinase GCN2 chr15 GO:0007610 Not Cancer Driver No 156 0.095 494 44 0.089 2
EIF4A3 EIF4A3 P38919 Eukaryotic initiation factor 4A-III chr17 GO:0007610 Not Cancer Driver No 50 0.122 57 6 0.105 1
EIF4EBP2 EIF4EBP2 Q13542 Eukaryotic translation initiation factor 4E-binding protein 2 chr10 GO:0007610 Not Cancer Driver No 17 0.142 118 14 0.119 0
EIF4E_ENST00000450253 EIF4E P06730 Eukaryotic translation initiation factor 4E chr4 GO:0007610 Not Cancer Driver No 26 0.12 54 6 0.111 0
EIF4G1_ENST00000346169 EIF4G1 Q04637 Eukaryotic translation initiation factor 4 gamma 1 chr3 GO:0007610 Not Cancer Driver No 229 0.143 1079 153 0.142 2
ELAVL4_ENST00000371821 ELAVL4 P26378 ELAV-like protein 4 chr1 GO:0007610 Not Cancer Driver No 118 0.306 117 34 0.291 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0007610 Not Cancer Driver No 42 0.107 357 30 0.084 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0007610 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0007610 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0007610 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPS8_ENST00000645775 EPS8 Q12929 Epidermal growth factor receptor kinase substrate 8 chr12 GO:0007610 Not Cancer Driver No 106 0.129 459 54 0.118 0
ETV1 ETV1 P50549 ETS translocation variant 1 chr7 GO:0007610 Census Yes 100 0.21 282 66 0.234 0
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0007610 Census Yes 107 0.143 58 7 0.121 12
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0007610 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAM19A2_ENST00000551619 TAFA2 Q8N3H0 Chemokine-like protein TAFA-2 chr12 GO:0007610 Not Cancer Driver No 55 0.42 4 1 0.25 0
FBXL20 FBXL20 Q96IG2 F-box/LRR-repeat protein 20 chr17 GO:0007610 Not Cancer Driver No 48 0.11 1 0 0.0 0
FEN1 FEN1 P39748 Flap endonuclease 1 chr11 GO:0007610 Census Yes 35 0.092 111 11 0.099 0
FEZF2_ENST00000475839 FEZF2 Q8TBJ5 Fez family zinc finger protein 2 chr3 GO:0007610 Not Cancer Driver No 65 0.142 144 14 0.097 0
FGF12 FGF12 P61328 Fibroblast growth factor 12 chr3 GO:0007610 Not Cancer Driver No 74 0.305 102 30 0.294 1
FGF13_ENST00000315930 FGF13 Q92913 Fibroblast growth factor 13 chrX GO:0007610 Not Cancer Driver No 70 0.286 96 33 0.344 2
FIG4 FIG4 Q92562 Polyphosphoinositide phosphatase chr6 GO:0007610 Not Cancer Driver No 114 0.126 177 26 0.147 7
FOS FOS P01100 Protein c-Fos chr14 GO:0007610 Not Cancer Driver No 45 0.118 245 33 0.135 0
FOSL1 FOSL1 P15407 Fos-related antigen 1 chr11 GO:0007610 Not Cancer Driver No 24 0.089 271 24 0.089 0
FOXA2_ENST00000377115 FOXA2 Q9Y261 Hepatocyte nuclear factor 3-beta chr20 GO:0007610 Compendium Yes 70 0.153 258 34 0.132 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0007610 Not Cancer Driver No 31 0.095 114 5 0.044 0
FXN FXN Q16595 Frataxin, mitochondrial chr9 GO:0007610 Not Cancer Driver No 16 0.076 73 0 0.0 8
FYN FYN P06241 Tyrosine-protein kinase Fyn chr6 GO:0007610 Not Cancer Driver No 92 0.171 70 13 0.186 0
FZD9 FZD9 O00144 Frizzled-9 chr7 GO:0007610 Not Cancer Driver No 55 0.093 61 0 0.0 0
GAA_ENST00000390015 GAA P10253 Lysosomal alpha-glucosidase chr17 GO:0007610 Not Cancer Driver No 101 0.106 147 18 0.122 131
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0007610 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0007610 Not Cancer Driver No 188 0.403 19 13 0.684 11
GAD1 GAD1 Q99259 Glutamate decarboxylase 1 chr2 GO:0007610 Not Cancer Driver No 113 0.19 55 5 0.091 1
GAL GAL P22466 Galanin peptides chr11 GO:0007610 Not Cancer Driver No 17 0.138 36 2 0.056 1
GALR2 GALR2 O43603 Galanin receptor type 2 chr17 GO:0007610 Not Cancer Driver No 40 0.103 0 0 0.0 0
GALR3 GALR3 O60755 Galanin receptor type 3 chr22 GO:0007610 Not Cancer Driver No 15 0.041 53 0 0.0 0
GATM GATM P50440 Glycine amidinotransferase, mitochondrial chr15 GO:0007610 Not Cancer Driver No 69 0.163 33 8 0.242 15
GBA_ENST00000368373 GBA P04062 Lysosomal acid glucosylceramidase chr1 GO:0007610 Not Cancer Driver No 74 0.138 38 5 0.132 171
GBX1 GBX1 Q14549 Homeobox protein GBX-1 chr7 GO:0007610 Not Cancer Driver No 40 0.11 267 28 0.105 0
GCG GCG P01275 Pro-glucagon chr2 GO:0007610 Not Cancer Driver No 49 0.272 82 22 0.268 0
GCNT4 GCNT4 Q9P109 Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 chr5 GO:0007610 Not Cancer Driver No 64 0.141 0 0 0.0 0
GDF15 GDF15 Q99988 Growth/differentiation factor 15 chr19 GO:0007610 Not Cancer Driver No 39 0.127 143 20 0.14 0
GDNF_ENST00000326524 GDNF P39905 Glial cell line-derived neurotrophic factor chr5 GO:0007610 Not Cancer Driver No 47 0.223 83 18 0.217 2
GFRAL GFRAL Q6UXV0 GDNF family receptor alpha-like chr6 GO:0007610 Not Cancer Driver No 176 0.447 5 2 0.4 0
GHRL_ENST00000457360 GHRL Q9UBU3 Appetite-regulating hormone chr3 GO:0007610 Not Cancer Driver No 20 0.171 52 11 0.212 0
GHSR GHSR Q92847 Growth hormone secretagogue receptor type 1 chr3 GO:0007610 Not Cancer Driver No 85 0.232 4 0 0.0 2
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0007610 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GIP GIP P09681 Gastric inhibitory polypeptide chr17 GO:0007610 Not Cancer Driver No 35 0.229 68 16 0.235 0
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0007610 Not Cancer Driver No 67 0.088 434 42 0.097 0
GJB4 GJB4 Q9NTQ9 Gap junction beta-4 protein chr1 GO:0007610 Not Cancer Driver No 69 0.259 7 1 0.143 5
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0007610 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLP1R GLP1R P43220 Glucagon-like peptide 1 receptor chr6 GO:0007610 Not Cancer Driver No 75 0.162 18 2 0.111 0
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0007610 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRB GLRB P48167 Glycine receptor subunit beta chr4 GO:0007610 Not Cancer Driver No 112 0.225 66 12 0.182 4
GLS GLS O94925 Glutaminase kidney isoform, mitochondrial chr2 GO:0007610 Not Cancer Driver No 71 0.106 187 9 0.048 3
GM2A GM2A P17900 Ganglioside GM2 activator chr5 GO:0007610 Not Cancer Driver No 26 0.135 0 0 0.0 2
GPI_ENST00000644934 GPI P06744 Glucose-6-phosphate isomerase chr19 GO:0007610 Not Cancer Driver No 77 0.138 73 11 0.151 24
GPR157 GPR157 Q5UAW9 G-protein coupled receptor 157 chr1 GO:0007610 Not Cancer Driver No 37 0.11 38 6 0.158 0
GPR176 GPR176 Q14439 G-protein coupled receptor 176 chr15 GO:0007610 Not Cancer Driver No 63 0.122 124 17 0.137 0
GPR52 GPR52 Q9Y2T5 G-protein coupled receptor 52 chr1 GO:0007610 Not Cancer Driver No 48 0.133 9 2 0.222 0
GPR88 GPR88 Q9GZN0 Probable G-protein coupled receptor 88 chr1 GO:0007610 Not Cancer Driver No 15 0.039 30 0 0.0 0
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0007610 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRID1 GRID1 Q9ULK0 Glutamate receptor ionotropic, delta-1 chr10 GO:0007610 Not Cancer Driver No 276 0.274 204 52 0.255 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0007610 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0007610 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0007610 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 GO:0007610 Not Cancer Driver No 413 0.278 426 147 0.345 11
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 GO:0007610 Not Cancer Driver No 125 0.094 467 15 0.032 1
GRM1_ENST00000282753 GRM1 Q13255 Metabotropic glutamate receptor 1 chr6 GO:0007610 Not Cancer Driver No 346 0.29 339 91 0.268 3
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0007610 Not Cancer Driver No 143 0.164 24 3 0.125 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0007610 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRM6_ENST00000517717 GRM6 O15303 Metabotropic glutamate receptor 6 chr5 GO:0007610 Not Cancer Driver No 200 0.228 113 23 0.204 6
GRM7 GRM7 Q14831 Metabotropic glutamate receptor 7 chr3 GO:0007610 Not Cancer Driver No 316 0.345 91 31 0.341 1
GRP GRP P07492 Gastrin-releasing peptide chr18 GO:0007610 Not Cancer Driver No 37 0.25 112 22 0.196 0
GRPR GRPR P30550 Gastrin-releasing peptide receptor chrX GO:0007610 Not Cancer Driver No 65 0.169 0 0 0.0 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0007610 Not Cancer Driver No 47 0.217 124 29 0.234 0
HCRT HCRT O43612 Orexin chr17 GO:0007610 Not Cancer Driver No 3 0.023 45 0 0.0 1
HCRTR1 HCRTR1 O43613 Orexin/Hypocretin receptor type 1 chr1 GO:0007610 Not Cancer Driver No 52 0.122 28 0 0.0 0
HCRTR2 HCRTR2 O43614 Orexin receptor type 2 chr6 GO:0007610 Not Cancer Driver No 154 0.347 38 13 0.342 0
HDAC2 HDAC2 Q92769 Histone deacetylase 2 chr6 GO:0007610 Not Cancer Driver No 46 0.094 145 14 0.097 0
HELT HELT A6NFD8 Hairy and enhancer of split-related protein HELT chr4 GO:0007610 Not Cancer Driver No 39 0.161 131 21 0.16 0
HEXB HEXB P07686 Beta-hexosaminidase subunit beta chr5 GO:0007610 Not Cancer Driver No 45 0.081 0 0 0.0 9
HIF1A_ENST00000337138 HIF1A Q16665 Hypoxia-inducible factor 1-alpha chr14 GO:0007610 Census Yes 118 0.143 435 51 0.117 0
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0007610 Not Cancer Driver No 154 0.129 686 96 0.14 0
HMGCR_ENST00000511206 HMGCR P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase chr5 GO:0007610 Not Cancer Driver No 84 0.095 112 12 0.107 0
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 GO:0007610 Not Cancer Driver No 46 0.13 243 32 0.132 0
HOMER2 HOMER2 Q9NSB8 Homer protein homolog 2 chr15 GO:0007610 Not Cancer Driver No 53 0.15 233 32 0.137 1
HOXA1_ENST00000643460 HOXA1 P49639 Homeobox protein Hox-A1 chr7 GO:0007610 Not Cancer Driver No 90 0.269 262 68 0.26 0
HOXB8 HOXB8 P17481 Homeobox protein Hox-B8 chr17 GO:0007610 Not Cancer Driver No 35 0.144 121 15 0.124 0
HOXD10 HOXD10 P28358 Homeobox protein Hox-D10 chr2 GO:0007610 Not Cancer Driver No 74 0.218 230 55 0.239 1
HOXD9 HOXD9 P28356 Homeobox protein Hox-D9 chr2 GO:0007610 Not Cancer Driver No 47 0.134 276 30 0.109 0
HPGDS HPGDS O60760 Hematopoietic prostaglandin D synthase chr4 GO:0007610 Not Cancer Driver No 34 0.171 0 0 0.0 0
HPRT1 HPRT1 P00492 Hypoxanthine-guanine phosphoribosyltransferase chrX GO:0007610 Not Cancer Driver No 22 0.101 3 0 0.0 62
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0007610 Not Cancer Driver No 96 0.197 122 26 0.213 0
HTR1A HTR1A P08908 5-hydroxytryptamine receptor 1A chr5 GO:0007610 Not Cancer Driver No 170 0.403 100 49 0.49 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0007610 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0007610 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0007610 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0007610 Not Cancer Driver No 140 0.306 40 11 0.275 0
HTRA2 HTRA2 O43464 Serine protease HTRA2, mitochondrial chr2 GO:0007610 Compendium Yes 44 0.096 127 9 0.071 2
HTT HTT P42858 Huntingtin chr4 GO:0007610 Not Cancer Driver No 336 0.107 666 69 0.104 2
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0007610 Not Cancer Driver No 22 0.247 10 2 0.2 0
ID2_ENST00000396290 ID2 Q02363 DNA-binding protein inhibitor ID-2 chr2 GO:0007610 Not Cancer Driver No 14 0.104 52 7 0.135 0
IDO1_ENST00000522495 IDO1 P14902 Indoleamine 2,3-dioxygenase 1 chr8 GO:0007610 Not Cancer Driver No 82 0.203 41 8 0.195 0
IFT20_ENST00000395418 IFT20 Q8IY31 Intraflagellar transport protein 20 homolog chr17 GO:0007610 Not Cancer Driver No 11 0.083 0 0 0.0 0
INPP5F INPP5F Q9Y2H2 Phosphatidylinositide phosphatase SAC2 chr10 GO:0007610 Not Cancer Driver No 138 0.122 394 45 0.114 0
INSR INSR P06213 Insulin receptor chr19 GO:0007610 Not Cancer Driver No 190 0.137 280 57 0.204 64
ITGA3 ITGA3 P26006 Integrin alpha-3 chr17 GO:0007610 Not Cancer Driver No 106 0.101 129 18 0.14 3
ITGA5 ITGA5 P08648 Integrin alpha-5 chr12 GO:0007610 Not Cancer Driver No 127 0.121 201 29 0.144 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0007610 Not Cancer Driver No 292 0.275 114 26 0.228 1
ITGB1_ENST00000302278 ITGB1 P05556 Integrin beta-1 chr10 GO:0007610 Not Cancer Driver No 103 0.129 84 10 0.119 0
ITPR3 ITPR3 Q14573 Inositol 1,4,5-trisphosphate receptor type 3 chr6 GO:0007610 Not Cancer Driver No 336 0.126 385 44 0.114 0
JPH3 JPH3 Q8WXH2 Junctophilin-3 chr16 GO:0007610 Not Cancer Driver No 130 0.174 534 92 0.172 0
JPH4_ENST00000356300 JPH4 Q96JJ6 Junctophilin-4 chr14 GO:0007610 Not Cancer Driver No 57 0.091 516 54 0.105 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0007610 Not Cancer Driver No 88 0.105 251 17 0.068 0
KCND2 KCND2 Q9NZV8 Potassium voltage-gated channel subfamily D member 2 chr7 GO:0007610 Not Cancer Driver No 220 0.349 195 62 0.318 0
KCNJ10 KCNJ10 P78508 ATP-sensitive inward rectifier potassium channel 10 chr1 GO:0007610 Not Cancer Driver No 78 0.206 28 10 0.357 8
KCNK10_ENST00000340700 KCNK10 P57789 Potassium channel subfamily K member 10 chr14 GO:0007610 Not Cancer Driver No 138 0.257 174 47 0.27 0
KCNK2 KCNK2 O95069 Potassium channel subfamily K member 2 chr1 GO:0007610 Not Cancer Driver No 109 0.256 40 10 0.25 0
KCNK4 KCNK4 Q9NYG8 Potassium channel subfamily K member 4 chr11 GO:0007610 Not Cancer Driver No 34 0.087 142 7 0.049 2
KCNQ1 KCNQ1 P51787 Potassium voltage-gated channel subfamily KQT member 1 chr11 GO:0007610 Not Cancer Driver No 78 0.115 219 20 0.091 132
KIRREL3 KIRREL3 Q8IZU9 Kin of IRRE-like protein 3 chr11 GO:0007610 Not Cancer Driver No 111 0.143 223 32 0.143 0
KIT KIT P10721 Mast/stem cell growth factor receptor Kit chr4 GO:0007610 Census, Compendium Yes 226 0.232 83 33 0.398 21
KLHL1 KLHL1 Q9NR64 Kelch-like protein 1 chr13 GO:0007610 Not Cancer Driver No 253 0.338 217 66 0.304 0
KLK8_ENST00000600767 KLK8 O60259 Kallikrein-8 chr19 GO:0007610 Not Cancer Driver No 65 0.25 76 15 0.197 0
KRAS KRAS P01116 GTPase KRas chr12 GO:0007610 Census, Compendium Yes 788 4.169 7 2 0.286 27
LDLR LDLR P01130 Low-density lipoprotein receptor chr19 GO:0007610 Not Cancer Driver No 119 0.138 63 3 0.048 104
LEP LEP P41159 Leptin chr7 GO:0007610 Not Cancer Driver No 29 0.174 0 0 0.0 2
LGI4 LGI4 Q8N135 Leucine-rich repeat LGI family member 4 chr19 GO:0007610 Not Cancer Driver No 54 0.101 4 1 0.25 2
LGMN_ENST00000334869 LGMN Q99538 Legumain chr14 GO:0007610 Not Cancer Driver No 57 0.132 112 19 0.17 0
LHX8 LHX8 Q68G74 LIM/homeobox protein Lhx8 chr1 GO:0007610 Not Cancer Driver No 93 0.261 157 47 0.299 0
LILRB2_ENST00000314446 LILRB2 Q8N423 Leukocyte immunoglobulin-like receptor subfamily B member 2 chr19 GO:0007610 Not Cancer Driver No 148 0.248 235 50 0.213 0
LMX1A_ENST00000294816 LMX1A Q8TE12 LIM homeobox transcription factor 1-alpha chr1 GO:0007610 Not Cancer Driver No 117 0.306 186 65 0.349 1
LPAR5 LPAR5 Q9H1C0 Lysophosphatidic acid receptor 5 chr12 GO:0007610 Not Cancer Driver No 40 0.108 57 7 0.123 0
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0007610 Not Cancer Driver No 519 0.205 90 17 0.189 23
LRRN4 LRRN4 Q8WUT4 Leucine-rich repeat neuronal protein 4 chr20 GO:0007610 Not Cancer Driver No 75 0.101 258 28 0.109 0
LRRTM1 LRRTM1 Q86UE6 Leucine-rich repeat transmembrane neuronal protein 1 chr2 GO:0007610 Not Cancer Driver No 172 0.33 57 17 0.298 0
LYPD1 LYPD1 Q8N2G4 Ly6/PLAUR domain-containing protein 1 chr2 GO:0007610 Not Cancer Driver No 20 0.142 5 0 0.0 0
MAFG MAFG O15525 Transcription factor MafG chr17 GO:0007610 Not Cancer Driver No 5 0.031 132 5 0.038 0
MAP1A MAP1A P78559 Microtubule-associated protein 1A chr15 GO:0007610 Not Cancer Driver No 369 0.132 2443 311 0.127 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0007610 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 GO:0007610 Not Cancer Driver No 49 0.059 568 27 0.048 0
MAPT_ENST00000262410 MAPT P10636 Microtubule-associated protein tau chr17 GO:0007610 Not Cancer Driver No 128 0.169 750 126 0.168 18
MBD2 MBD2 Q9UBB5 Methyl-CpG-binding domain protein 2 chr18 GO:0007610 Not Cancer Driver No 26 0.063 384 25 0.065 0
MC3R MC3R P41968 Melanocortin receptor 3 chr20 GO:0007610 Not Cancer Driver No 96 0.297 0 0 0.0 0
MC4R MC4R P32245 Melanocortin receptor 4 chr18 GO:0007610 Not Cancer Driver No 57 0.172 2 0 0.0 29
MCHR1 MCHR1 Q99705 Melanin-concentrating hormone receptor 1 chr22 GO:0007610 Not Cancer Driver No 64 0.152 100 12 0.12 0
MCOLN3 MCOLN3 Q8TDD5 Mucolipin-3 chr1 GO:0007610 Not Cancer Driver No 102 0.184 9 2 0.222 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0007610 Not Cancer Driver No 15 0.105 20 2 0.1 0
MECP2_ENST00000303391 MECP2 P51608 Methyl-CpG-binding protein 2 chrX GO:0007610 Not Cancer Driver No 75 0.154 483 74 0.153 46
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0007610 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:0007610 Not Cancer Driver No 89 0.228 267 62 0.232 0
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 GO:0007610 Not Cancer Driver No 94 0.197 358 76 0.212 0
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0007610 Not Cancer Driver No 61 0.112 36 4 0.111 7
MKKS MKKS Q9NPJ1 McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin chr20 GO:0007610 Not Cancer Driver No 56 0.098 6 1 0.167 22
MME_ENST00000492661 MME P08473 Neprilysin chr3 GO:0007610 Not Cancer Driver No 189 0.252 40 17 0.425 4
MMP17 MMP17 Q9ULZ9 Matrix metalloproteinase-17 chr12 GO:0007610 Not Cancer Driver No 93 0.154 241 26 0.108 0
MORC1 MORC1 Q86VD1 MORC family CW-type zinc finger protein 1 chr3 GO:0007610 Not Cancer Driver No 300 0.305 252 77 0.306 0
MRAP2 MRAP2 Q96G30 Melanocortin-2 receptor accessory protein 2 chr6 GO:0007610 Not Cancer Driver No 55 0.268 75 17 0.227 0
MTA1 MTA1 Q13330 Metastasis-associated protein MTA1 chr14 GO:0007610 Not Cancer Driver No 92 0.129 327 42 0.128 0
MTNR1A MTNR1A P48039 Melatonin receptor type 1A chr4 GO:0007610 Not Cancer Driver No 72 0.206 0 0 0.0 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0007610 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUSK MUSK O15146 Muscle, skeletal receptor tyrosine-protein kinase chr9 GO:0007610 Not Cancer Driver No 188 0.216 35 7 0.2 7
MYH14_ENST00000596571 MYH14 Q7Z406 Myosin-14 chr19 GO:0007610 Not Cancer Driver No 275 0.138 1215 169 0.139 5
MYO15A_ENST00000647165 MYO15A Q9UKN7 Unconventional myosin-XV chr17 GO:0007610 Not Cancer Driver No 471 0.133 1386 172 0.124 4
NAGLU NAGLU P54802 Alpha-N-acetylglucosaminidase chr17 GO:0007610 Not Cancer Driver No 70 0.094 18 1 0.056 68
NAV2 NAV2 Q8IVL1 Neuron navigator 2 chr11 GO:0007610 Not Cancer Driver No 367 0.148 1866 276 0.148 0
NCOA2 NCOA2 Q15596 Nuclear receptor coactivator 2 chr8 GO:0007610 Census, Compendium Yes 210 0.143 1281 185 0.144 0
NCOR1 NCOR1 O75376 Nuclear receptor corepressor 1 chr17 GO:0007610 Census, Compendium Yes 352 0.144 2347 340 0.145 0
NCSTN NCSTN Q92542 Nicastrin chr1 GO:0007610 Not Cancer Driver No 94 0.133 72 11 0.153 1
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 GO:0007610 Not Cancer Driver No 44 0.125 90 11 0.122 0
NEGR1 NEGR1 Q7Z3B1 Neuronal growth regulator 1 chr1 GO:0007610 Not Cancer Driver No 90 0.254 61 25 0.41 0
NETO1 NETO1 Q8TDF5 Neuropilin and tolloid-like protein 1 chr18 GO:0007610 Not Cancer Driver No 186 0.349 103 33 0.32 0
NEUROD2 NEUROD2 Q15784 Neurogenic differentiation factor 2 chr17 GO:0007610 Not Cancer Driver No 26 0.068 210 14 0.067 2
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0007610 Not Cancer Driver No 27 0.114 178 18 0.101 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0007610 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFATC4_ENST00000250373 NFATC4 Q14934 Nuclear factor of activated T-cells, cytoplasmic 4 chr14 GO:0007610 Not Cancer Driver No 155 0.172 685 120 0.175 0
NGF NGF P01138 Beta-nerve growth factor chr1 GO:0007610 Not Cancer Driver No 66 0.274 93 25 0.269 1
NHLH2_ENST00000320238 NHLH2 Q02577 Helix-loop-helix protein 2 chr1 GO:0007610 Not Cancer Driver No 19 0.141 83 8 0.096 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0007610 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0007610 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0007610 Not Cancer Driver No 279 0.342 211 81 0.384 0
NLGN4Y NLGN4Y Q8NFZ3 Neuroligin-4, Y-linked chrY GO:0007610 Not Cancer Driver No 94 0.115 206 26 0.126 0
NMS NMS Q5H8A3 Neuromedin-S chr2 GO:0007610 Not Cancer Driver No 41 0.268 21 7 0.333 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0007610 Not Cancer Driver No 139 0.335 5 1 0.2 0
NPAS1_ENST00000449844 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 GO:0007610 Not Cancer Driver No 53 0.09 309 23 0.074 0
NPAS4 NPAS4 Q8IUM7 Neuronal PAS domain-containing protein 4 chr11 GO:0007610 Not Cancer Driver No 229 0.286 429 114 0.266 0
NPB NPB Q8NG41 Neuropeptide B chr17 GO:0007610 Not Cancer Driver No 6 0.048 22 1 0.045 0
NPC1 NPC1 O15118 NPC intracellular cholesterol transporter 1 chr18 GO:0007610 Not Cancer Driver No 155 0.121 24 0 0.0 150
NPHP1_ENST00000393272 NPHP1 O15259 Nephrocystin-1 chr2 GO:0007610 Not Cancer Driver No 108 0.148 259 32 0.124 1
NPHP4 NPHP4 O75161 Nephrocystin-4 chr1 GO:0007610 Not Cancer Driver No 176 0.123 469 54 0.115 17
NPS NPS P0C0P6 Neuropeptide S chr10 GO:0007610 Not Cancer Driver No 27 0.303 5 2 0.4 0
NPSR1_ENST00000360581 NPSR1 Q6W5P4 Neuropeptide S receptor chr7 GO:0007610 Not Cancer Driver No 111 0.299 9 7 0.778 0
NPTN NPTN Q9Y639 Neuroplastin chr15 GO:0007610 Not Cancer Driver No 47 0.118 118 9 0.076 0
NPTX2 NPTX2 P47972 Neuronal pentraxin-2 chr7 GO:0007610 Not Cancer Driver No 78 0.181 165 10 0.061 0
NPW NPW Q8N729 Neuropeptide W chr16 GO:0007610 Not Cancer Driver No 14 0.085 76 5 0.066 0
NPY1R NPY1R P25929 Neuropeptide Y receptor type 1 chr4 GO:0007610 Not Cancer Driver No 114 0.297 4 0 0.0 0
NPY2R NPY2R P49146 Neuropeptide Y receptor type 2 chr4 GO:0007610 Not Cancer Driver No 119 0.312 53 16 0.302 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0007610 Not Cancer Driver No 144 0.324 44 16 0.364 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0007610 Not Cancer Driver No 29 0.299 43 19 0.442 0
NR1D2 NR1D2 Q14995 Nuclear receptor subfamily 1 group D member 2 chr3 GO:0007610 Not Cancer Driver No 76 0.131 223 25 0.112 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0007610 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0007610 Not Cancer Driver No 110 0.184 261 38 0.146 0
NRG1_ENST00000405005 NRG1 Q02297 Pro-neuregulin-1, membrane-bound isoform chr8 GO:0007610 Census, Compendium Yes 159 0.248 528 132 0.25 0
NRGN NRGN Q92686 Neurogranin chr11 GO:0007610 Not Cancer Driver No 5 0.064 76 5 0.066 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0007610 Not Cancer Driver No 593 0.401 301 110 0.365 0
NRXN2_ENST00000377551 NRXN2 Q9P2S2 Neurexin-2 chr11 GO:0007610 Not Cancer Driver No 278 0.162 547 80 0.146 0
NTAN1 NTAN1 Q96AB6 Protein N-terminal asparagine amidohydrolase chr16 GO:0007610 Not Cancer Driver No 27 0.087 87 6 0.069 0
NTF3_ENST00000331010 NTF3 P20783 Neurotrophin-3 chr12 GO:0007610 Not Cancer Driver No 52 0.202 99 21 0.212 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0007610 Not Cancer Driver No 21 0.1 56 4 0.071 0
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0007610 Census, Compendium Yes 168 0.211 57 8 0.14 25
NTRK2_ENST00000323115 NTRK2 Q16620 BDNF/NT-3 growth factors receptor chr9 GO:0007610 Not Cancer Driver No 155 0.189 117 18 0.154 1
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0007610 Not Cancer Driver No 85 0.203 23 1 0.043 0
OBP2B OBP2B Q9NPH6 Odorant-binding protein 2b chr9 GO:0007610 Not Cancer Driver No 28 0.165 41 11 0.268 0
OPN4_ENST00000241891 OPN4 Q9UHM6 Melanopsin chr10 GO:0007610 Not Cancer Driver No 84 0.176 88 9 0.102 0
OPRD1 OPRD1 P41143 Delta-type opioid receptor chr1 GO:0007610 Not Cancer Driver No 91 0.245 30 3 0.1 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0007610 Not Cancer Driver No 117 0.308 18 5 0.278 0
OPRL1_ENST00000336866 OPRL1 P41146 Nociceptin receptor chr20 GO:0007610 Not Cancer Driver No 81 0.219 0 0 0.0 0
OPRM1_ENST00000330432 OPRM1 P35372 Mu-type opioid receptor chr6 GO:0007610 Not Cancer Driver No 107 0.268 58 27 0.466 0
ORMDL3_ENST00000304046 ORMDL3 Q8N138 ORM1-like protein 3 chr17 GO:0007610 Not Cancer Driver No 22 0.144 9 1 0.111 0
OTOG OTOG Q6ZRI0 Otogelin chr11 GO:0007610 Not Cancer Driver No 62 0.021 728 27 0.037 1
OXR1 OXR1 Q8N573 Oxidation resistance protein 1 chr8 GO:0007610 Not Cancer Driver No 126 0.144 544 76 0.14 0
OXT OXT P01178 Oxytocin-neurophysin 1 chr20 GO:0007610 Not Cancer Driver No 10 0.08 0 0 0.0 0
OXTR OXTR P30559 Oxytocin receptor chr3 GO:0007610 Not Cancer Driver No 46 0.118 18 0 0.0 0
P2RX2_ENST00000643471 P2RX2 Q9UBL9 P2X purinoceptor 2 chr12 GO:0007610 Not Cancer Driver No 62 0.132 104 13 0.125 2
P2RX3 P2RX3 P56373 P2X purinoceptor 3 chr11 GO:0007610 Not Cancer Driver No 85 0.214 15 6 0.4 0
P2RX4_ENST00000337233 P2RX4 Q99571 P2X purinoceptor 4 chr12 GO:0007610 Not Cancer Driver No 36 0.093 0 0 0.0 0
P2RY1 P2RY1 P47900 P2Y purinoceptor 1 chr3 GO:0007610 Not Cancer Driver No 60 0.161 16 1 0.062 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0007610 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAIP2_ENST00000265192 PAIP2 Q9BPZ3 Polyadenylate-binding protein-interacting protein 2 chr5 GO:0007610 Not Cancer Driver No 11 0.087 88 10 0.114 0
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 GO:0007610 Not Cancer Driver No 226 0.314 407 123 0.302 0
PAK6_ENST00000260404 PAK6 Q9NQU5 Serine/threonine-protein kinase PAK 6 chr15 GO:0007610 Not Cancer Driver No 82 0.12 398 52 0.131 0
PARK7_ENST00000377488 PARK7 Q99497 Parkinson disease protein 7 chr1 GO:0007610 Not Cancer Driver No 11 0.058 30 0 0.0 5
PAX5 PAX5 Q02548 Paired box protein Pax-5 chr9 GO:0007610 Census Yes 83 0.212 291 62 0.213 1
PBX3 PBX3 P40426 Pre-B-cell leukemia transcription factor 3 chr9 GO:0007610 Not Cancer Driver No 59 0.136 290 40 0.138 0
PCDH17 PCDH17 O14917 Protocadherin-17 chr13 GO:0007610 Compendium Yes 399 0.344 643 210 0.327 0
PCM1 PCM1 Q15154 Pericentriolar material 1 protein chr8 GO:0007610 Census Yes 152 0.075 1665 134 0.08 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0007610 Not Cancer Driver No 114 0.213 132 30 0.227 0
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0007610 Not Cancer Driver No 109 0.408 142 62 0.437 0
PEX13 PEX13 Q92968 Peroxisomal membrane protein PEX13 chr2 GO:0007610 Not Cancer Driver No 38 0.094 133 14 0.105 1
PGRMC1 PGRMC1 O00264 Membrane-associated progesterone receptor component 1 chrX GO:0007610 Not Cancer Driver No 30 0.154 74 16 0.216 0
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0007610 Census Yes 89 0.137 320 42 0.131 0
PIRT PIRT P0C851 Phosphoinositide-interacting protein chr17 GO:0007610 Not Cancer Driver No 24 0.175 3 1 0.333 0
PITX3_ENST00000539804 PITX3 O75364 Pituitary homeobox 3 chr10 GO:0007610 Not Cancer Driver No 24 0.079 155 12 0.077 1
PJA2 PJA2 O43164 E3 ubiquitin-protein ligase Praja-2 chr5 GO:0007610 Not Cancer Driver No 80 0.113 598 66 0.11 0
PLA2G6 PLA2G6 O60733 85/88 kDa calcium-independent phospholipase A2 chr22 GO:0007610 Not Cancer Driver No 108 0.134 148 23 0.155 11
PLCB1 PLCB1 Q9NQ66 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 chr20 GO:0007610 Not Cancer Driver No 313 0.257 481 104 0.216 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0007610 Not Cancer Driver No 92 0.134 178 21 0.118 0
PMCH PMCH P20382 Pro-MCH chr12 GO:0007610 Not Cancer Driver No 22 0.133 63 8 0.127 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 GO:0007610 Not Cancer Driver No 53 0.151 30 9 0.3 3
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0007610 Not Cancer Driver No 51 0.122 273 34 0.125 1
PPARA_ENST00000402126 PPARA Q07869 Peroxisome proliferator-activated receptor alpha chr22 GO:0007610 Not Cancer Driver No 63 0.135 68 9 0.132 0
PPP1R1B PPP1R1B Q9UD71 Protein phosphatase 1 regulatory subunit 1B chr17 GO:0007610 Not Cancer Driver No 30 0.147 204 30 0.147 0
PPP1R9B PPP1R9B Q96SB3 Neurabin-2 chr17 GO:0007610 Not Cancer Driver No 47 0.058 695 35 0.05 0
PPP3CB_ENST00000360663 PPP3CB P16298 Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform chr10 GO:0007610 Not Cancer Driver No 67 0.128 139 18 0.129 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0007610 Not Cancer Driver No 37 0.121 0 0 0.0 23
PPY PPY P01298 Pancreatic prohormone chr17 GO:0007610 Not Cancer Driver No 15 0.158 19 6 0.316 0
PREX2 PREX2 Q70Z35 Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein chr8 GO:0007610 Census, Compendium Yes 492 0.306 234 68 0.291 0
PRKAA1_ENST00000397128 PRKAA1 Q13131 5'-AMP-activated protein kinase catalytic subunit alpha-1 chr5 GO:0007610 Not Cancer Driver No 72 0.129 124 17 0.137 0
PRKAR1B_ENST00000403562 PRKAR1B P31321 cAMP-dependent protein kinase type I-beta regulatory subunit chr7 GO:0007610 Not Cancer Driver No 53 0.139 71 13 0.183 0
PRKAR2B PRKAR2B P31323 cAMP-dependent protein kinase type II-beta regulatory subunit chr7 GO:0007610 Not Cancer Driver No 60 0.144 125 4 0.032 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0007610 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0007610 Not Cancer Driver No 172 0.247 151 43 0.285 5
PRKCZ PRKCZ Q05513 Protein kinase C zeta type chr1 GO:0007610 Not Cancer Driver No 70 0.118 116 11 0.095 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0007610 Not Cancer Driver No 110 0.237 78 15 0.192 31
PRLH PRLH P81277 Prolactin-releasing peptide chr2 GO:0007610 Not Cancer Driver No 10 0.115 28 3 0.107 0
PRLHR_ENST00000636925 PRLHR P49683 Prolactin-releasing peptide receptor chr10 GO:0007610 Not Cancer Driver No 72 0.195 17 2 0.118 0
PRNP PRNP P04156 Major prion protein chr20 GO:0007610 Not Cancer Driver No 36 0.142 115 7 0.061 18
PRRT1 PRRT1 Q99946 Proline-rich transmembrane protein 1 chr6 GO:0007610 Not Cancer Driver No 36 0.118 190 19 0.1 0
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0007610 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTCHD1 PTCHD1 Q96NR3 Patched domain-containing protein 1 chrX GO:0007610 Not Cancer Driver No 154 0.173 11 6 0.545 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0007610 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTGS2 PTGS2 P35354 Prostaglandin G/H synthase 2 chr1 GO:0007610 Not Cancer Driver No 105 0.174 30 5 0.167 0
PTN PTN P21246 Pleiotrophin chr7 GO:0007610 Not Cancer Driver No 43 0.256 51 11 0.216 0
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0007610 Not Cancer Driver No 480 0.207 978 216 0.221 0
PUM1_ENST00000257075 PUM1 Q14671 Pumilio homolog 1 chr1 GO:0007610 Not Cancer Driver No 150 0.126 640 77 0.12 3
PYY PYY P10082 Peptide YY chr17 GO:0007610 Not Cancer Driver No 19 0.196 38 8 0.211 0
QRFP QRFP P83859 Orexigenic neuropeptide QRFP chr9 GO:0007610 Not Cancer Driver No 20 0.147 49 12 0.245 0
RAG1 RAG1 P15918 V(D)J recombination-activating protein 1 chr11 GO:0007610 Not Cancer Driver No 204 0.196 208 43 0.207 36
RAPGEF3 RAPGEF3 O95398 Rap guanine nucleotide exchange factor 3 chr12 GO:0007610 Not Cancer Driver No 97 0.105 197 19 0.096 0
RASD2 RASD2 Q96D21 GTP-binding protein Rhes chr22 GO:0007610 Not Cancer Driver No 59 0.222 14 2 0.143 0
RASGRF1 RASGRF1 Q13972 Ras-specific guanine nucleotide-releasing factor 1 chr15 GO:0007610 Not Cancer Driver No 226 0.178 332 64 0.193 0
RCAN1_ENST00000313806 RCAN1 P53805 Calcipressin-1 chr21 GO:0007610 Not Cancer Driver No 26 0.103 104 7 0.067 0
RELN RELN P78509 Reelin chr7 GO:0007610 Not Cancer Driver No 761 0.22 107 19 0.178 7
REN REN P00797 Renin chr1 GO:0007610 Not Cancer Driver No 60 0.148 10 0 0.0 3
RGS14 RGS14 O43566 Regulator of G-protein signaling 14 chr5 GO:0007610 Not Cancer Driver No 57 0.101 309 37 0.12 0
RIC8A_ENST00000526104 RIC8A Q9NPQ8 Synembryn-A chr11 GO:0007610 Not Cancer Driver No 63 0.119 163 23 0.141 0
RMI1 RMI1 Q9H9A7 RecQ-mediated genome instability protein 1 chr9 GO:0007610 Not Cancer Driver No 67 0.107 243 26 0.107 0
RNF180 RNF180 Q86T96 E3 ubiquitin-protein ligase RNF180 chr5 GO:0007610 Not Cancer Driver No 80 0.135 190 26 0.137 0
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0007610 Not Cancer Driver No 45 0.086 226 26 0.115 0
RPTOR RPTOR Q8N122 Regulatory-associated protein of mTOR chr17 GO:0007610 Not Cancer Driver No 176 0.132 241 21 0.087 0
S100B S100B P04271 Protein S100-B chr21 GO:0007610 Not Cancer Driver No 17 0.185 13 1 0.077 0
SCN1A_ENST00000423058 SCN1A P35498 Sodium channel protein type 1 subunit alpha chr2 GO:0007610 Not Cancer Driver No 497 0.247 455 121 0.266 396
SCN2A_ENST00000637266 SCN2A Q99250 Sodium channel protein type 2 subunit alpha chr2 GO:0007610 Not Cancer Driver No 502 0.25 435 133 0.306 65
SCN9A_ENST00000642356 SCN9A Q15858 Sodium channel protein type 9 subunit alpha chr2 GO:0007610 Not Cancer Driver No 461 0.232 490 126 0.257 21
SDK1 SDK1 Q7Z5N4 Protein sidekick-1 chr7 GO:0007610 Not Cancer Driver No 526 0.238 784 179 0.228 0
SELENOP_ENST00000506577 SELENOP P49908 Selenoprotein P chr5 GO:0007610 Not Cancer Driver No 67 0.176 154 19 0.123 0
SEPT5 SEPTIN5 Q99719 Septin-5 chr22 GO:0007610 Not Cancer Driver No 50 0.136 76 5 0.066 0
SERPINF1 SERPINF1 P36955 Pigment epithelium-derived factor chr17 GO:0007610 Not Cancer Driver No 51 0.122 57 5 0.088 0
SEZ6 SEZ6 Q53EL9 Seizure protein 6 homolog chr17 GO:0007610 Not Cancer Driver No 120 0.121 345 54 0.157 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0007610 Census, Compendium Yes 58 0.135 86 16 0.186 0
SHANK1 SHANK1 Q9Y566 SH3 and multiple ankyrin repeat domains protein 1 chr19 GO:0007610 Not Cancer Driver No 288 0.133 1659 186 0.112 0
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:0007610 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SHISA7 SHISA7 A6NL88 Protein shisa-7 chr19 GO:0007610 Not Cancer Driver No 13 0.024 429 12 0.028 0
SLC11A2_ENST00000262051 SLC11A2 P49281 Natural resistance-associated macrophage protein 2 chr12 GO:0007610 Not Cancer Driver No 60 0.106 38 5 0.132 3
SLC12A5 SLC12A5 Q9H2X9 Solute carrier family 12 member 5 chr20 GO:0007610 Not Cancer Driver No 263 0.231 290 59 0.203 5
SLC16A1 SLC16A1 P53985 Monocarboxylate transporter 1 chr1 GO:0007610 Not Cancer Driver No 69 0.138 70 3 0.043 3
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 GO:0007610 Not Cancer Driver No 105 0.204 23 7 0.304 1
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0007610 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0007610 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0007610 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC24A2 SLC24A2 Q9UI40 Sodium/potassium/calcium exchanger 2 chr9 GO:0007610 Not Cancer Driver No 120 0.182 144 24 0.167 0
SLC24A4 SLC24A4 Q8NFF2 Sodium/potassium/calcium exchanger 4 chr14 GO:0007610 Not Cancer Driver No 121 0.195 85 14 0.165 2
SLC2A4 SLC2A4 P14672 Solute carrier family 2, facilitated glucose transporter member 4 chr17 GO:0007610 Not Cancer Driver No 71 0.139 43 8 0.186 1
SLC4A10 SLC4A10 Q6U841 Sodium-driven chloride bicarbonate exchanger chr2 GO:0007610 Not Cancer Driver No 221 0.198 340 68 0.2 0
SLC6A1_ENST00000643498 SLC6A1 P30531 Sodium- and chloride-dependent GABA transporter 1 chr3 GO:0007610 Not Cancer Driver No 119 0.199 24 9 0.375 4
SLC6A3 SLC6A3 Q01959 Sodium-dependent dopamine transporter chr5 GO:0007610 Not Cancer Driver No 150 0.242 31 8 0.258 2
SLC6A4_ENST00000401766 SLC6A4 P31645 Sodium-dependent serotonin transporter chr17 GO:0007610 Not Cancer Driver No 101 0.16 73 12 0.164 0
SLC7A11 SLC7A11 Q9UPY5 Cystine/glutamate transporter chr4 GO:0007610 Not Cancer Driver No 70 0.14 15 2 0.133 0
SLC8A2 SLC8A2 Q9UPR5 Sodium/calcium exchanger 2 chr19 GO:0007610 Not Cancer Driver No 117 0.127 143 19 0.133 0
SLC8A3 SLC8A3 P57103 Sodium/calcium exchanger 3 chr14 GO:0007610 Not Cancer Driver No 263 0.284 152 35 0.23 0
SLITRK1 SLITRK1 Q96PX8 SLIT and NTRK-like protein 1 chr13 GO:0007610 Not Cancer Driver No 299 0.43 126 64 0.508 0
SLITRK6_ENST00000643778 SLITRK6 Q9H5Y7 SLIT and NTRK-like protein 6 chr13 GO:0007610 Not Cancer Driver No 244 0.29 225 53 0.236 0
SLURP1 SLURP1 P55000 Secreted Ly-6/uPAR-related protein 1 chr8 GO:0007610 Not Cancer Driver No 19 0.184 0 0 0.0 8
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 GO:0007610 Not Cancer Driver No 61 0.296 176 49 0.278 1
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0007610 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNCG SNCG O76070 Gamma-synuclein chr10 GO:0007610 Not Cancer Driver No 11 0.087 111 10 0.09 0
SOBP SOBP A7XYQ1 Sine oculis-binding protein homolog chr6 GO:0007610 Not Cancer Driver No 108 0.124 702 78 0.111 0
SOD1 SOD1 P00441 Superoxide dismutase [Cu-Zn] chr21 GO:0007610 Not Cancer Driver No 16 0.104 93 9 0.097 79
SOD2_ENST00000367055 SOD2 P04179 Superoxide dismutase [Mn], mitochondrial chr6 GO:0007610 Not Cancer Driver No 32 0.144 25 5 0.2 0
SORCS3 SORCS3 Q9UPU3 VPS10 domain-containing receptor SorCS3 chr10 GO:0007610 Not Cancer Driver No 405 0.331 221 13 0.059 0
SPG11 SPG11 Q96JI7 Spatacsin chr15 GO:0007610 Not Cancer Driver No 252 0.103 126 12 0.095 1
SPTBN2 SPTBN2 O15020 Spectrin beta chain, non-erythrocytic 2 chr11 GO:0007610 Not Cancer Driver No 317 0.133 877 126 0.144 2
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0007610 Not Cancer Driver No 312 0.122 866 103 0.119 0
SRD5A1 SRD5A1 P18405 3-oxo-5-alpha-steroid 4-dehydrogenase 1 chr5 GO:0007610 Not Cancer Driver No 35 0.135 0 0 0.0 0
SRF SRF P11831 Serum response factor chr6 GO:0007610 Not Cancer Driver No 44 0.087 443 42 0.095 0
SRPX2 SRPX2 O60687 Sushi repeat-containing protein SRPX2 chrX GO:0007610 Not Cancer Driver No 86 0.185 64 13 0.203 0
STAT3 STAT3 P40763 Signal transducer and activator of transcription 3 chr17 GO:0007610 Census, Compendium Yes 110 0.143 152 15 0.099 19
STRA6_ENST00000323940 STRA6 Q9BX79 Receptor for retinol uptake STRA6 chr15 GO:0007610 Not Cancer Driver No 77 0.115 84 14 0.167 6
STRBP_ENST00000348403 STRBP Q96SI9 Spermatid perinuclear RNA-binding protein chr9 GO:0007610 Not Cancer Driver No 74 0.11 306 31 0.101 0
STRN STRN O43815 Striatin chr2 GO:0007610 Census, Compendium Yes 97 0.124 348 43 0.124 0
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0007610 Not Cancer Driver No 153 0.114 830 90 0.108 2
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0007610 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYT11 SYT11 Q9BT88 Synaptotagmin-11 chr1 GO:0007610 Not Cancer Driver No 64 0.148 105 23 0.219 0
SYT4 SYT4 Q9H2B2 Synaptotagmin-4 chr18 GO:0007610 Not Cancer Driver No 111 0.261 107 41 0.383 0
TACO1 TACO1 Q9BSH4 Translational activator of cytochrome c oxidase 1 chr17 GO:0007610 Not Cancer Driver No 21 0.071 111 2 0.018 0
TACR1 TACR1 P25103 Substance-P receptor chr2 GO:0007610 Not Cancer Driver No 69 0.17 28 2 0.071 0
TACR2 TACR2 P21452 Substance-K receptor chr10 GO:0007610 Not Cancer Driver No 61 0.153 11 4 0.364 0
TAL1 TAL1 P17542 T-cell acute lymphocytic leukemia protein 1 chr1 GO:0007610 Census Yes 54 0.163 305 53 0.174 0
TANC1 TANC1 Q9C0D5 Protein TANC1 chr2 GO:0007610 Not Cancer Driver No 237 0.127 906 101 0.111 0
TAS2R5 TAS2R5 Q9NYW4 Taste receptor type 2 member 5 chr7 GO:0007610 Not Cancer Driver No 32 0.107 0 0 0.0 0
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 GO:0007610 Not Cancer Driver No 88 0.129 413 56 0.136 5
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0007610 Not Cancer Driver No 35 0.088 197 12 0.061 4
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0007610 Not Cancer Driver No 19 0.095 134 4 0.03 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0007610 Not Cancer Driver No 61 0.116 149 21 0.141 38
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0007610 Not Cancer Driver No 188 0.161 320 58 0.181 0
THBS4 THBS4 P35443 Thrombospondin-4 chr5 GO:0007610 Not Cancer Driver No 137 0.143 281 40 0.142 0
THRA THRA P10827 Thyroid hormone receptor alpha chr17 GO:0007610 Not Cancer Driver No 69 0.141 207 30 0.145 2
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0007610 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 GO:0007610 Not Cancer Driver No 32 0.199 26 7 0.269 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0007610 Not Cancer Driver No 108 0.138 0 0 0.0 0
TMOD1_ENST00000395211 TMOD1 P28289 Tropomodulin-1 chr9 GO:0007610 Not Cancer Driver No 41 0.114 195 29 0.149 0
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0007610 Not Cancer Driver No 33 0.094 216 22 0.102 0
TNR TNR Q92752 Tenascin-R chr1 GO:0007610 Not Cancer Driver No 496 0.365 358 128 0.358 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0007610 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 GO:0007610 Not Cancer Driver No 58 0.138 13 1 0.077 0
TPGS1 TPGS1 Q6ZTW0 Tubulin polyglutamylase complex subunit 1 chr19 GO:0007610 Not Cancer Driver No 6 0.021 62 2 0.032 0
TREM2 TREM2 Q9NZC2 Triggering receptor expressed on myeloid cells 2 chr6 GO:0007610 Not Cancer Driver No 43 0.187 27 2 0.074 1
TRH TRH P20396 Pro-thyrotropin-releasing hormone chr3 GO:0007610 Not Cancer Driver No 45 0.186 217 41 0.189 0
TRMT1L TRMT1L Q7Z2T5 TRMT1-like protein chr1 GO:0007610 Not Cancer Driver No 71 0.097 241 19 0.079 0
TRPV1_ENST00000399756 TRPV1 Q8NER1 Transient receptor potential cation channel subfamily V member 1 chr17 GO:0007610 Not Cancer Driver No 93 0.111 155 18 0.116 0
TSC1 TSC1 Q92574 Hamartin chr9 GO:0007610 Census, Compendium Yes 135 0.116 732 78 0.107 11
TSPO_ENST00000329563 TSPO P30536 Translocator protein chr22 GO:0007610 Not Cancer Driver No 5 0.03 1 0 0.0 0
TTBK1 TTBK1 Q5TCY1 Tau-tubulin kinase 1 chr6 GO:0007610 Not Cancer Driver No 193 0.146 1045 154 0.147 0
TTC36 TTC36 A6NLP5 Tetratricopeptide repeat protein 36 chr11 GO:0007610 Not Cancer Driver No 13 0.069 98 12 0.122 0
UBA6 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 GO:0007610 Not Cancer Driver No 133 0.126 90 10 0.111 0
UBE2Q1 UBE2Q1 Q7Z7E8 Ubiquitin-conjugating enzyme E2 Q1 chr1 GO:0007610 Not Cancer Driver No 45 0.107 173 16 0.092 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0007610 Not Cancer Driver No 141 0.161 136 22 0.162 0
UBR3 UBR3 Q6ZT12 E3 ubiquitin-protein ligase UBR3 chr2 GO:0007610 Not Cancer Driver No 154 0.082 339 28 0.083 0
UCHL1 UCHL1 P09936 Ubiquitin carboxyl-terminal hydrolase isozyme L1 chr4 GO:0007610 Not Cancer Driver No 33 0.148 34 7 0.206 4
UCN UCN P55089 Urocortin chr2 GO:0007610 Not Cancer Driver No 7 0.056 61 4 0.066 0
USP2 USP2 O75604 Ubiquitin carboxyl-terminal hydrolase 2 chr11 GO:0007610 Not Cancer Driver No 88 0.145 213 39 0.183 0
USP46 USP46 P62068 Ubiquitin carboxyl-terminal hydrolase 46 chr4 GO:0007610 Not Cancer Driver No 48 0.131 28 4 0.143 0
VIP VIP P01282 VIP peptides chr6 GO:0007610 Not Cancer Driver No 58 0.341 77 25 0.325 0
VLDLR VLDLR P98155 Very low-density lipoprotein receptor chr9 GO:0007610 Not Cancer Driver No 90 0.103 55 3 0.055 0
VPS13A VPS13A Q96RL7 Intermembrane lipid transfer protein VPS13A chr9 GO:0007610 Not Cancer Driver No 375 0.118 208 18 0.087 6
VWA1 VWA1 Q6PCB0 von Willebrand factor A domain-containing protein 1 chr1 GO:0007610 Not Cancer Driver No 18 0.04 221 10 0.045 0
WFS1_ENST00000503569 WFS1 O76024 Wolframin chr4 GO:0007610 Not Cancer Driver No 105 0.118 203 10 0.049 39
YTHDF1 YTHDF1 Q9BYJ9 YTH domain-containing family protein 1 chr20 GO:0007610 Not Cancer Driver No 87 0.156 369 46 0.125 0
ZDHHC8_ENST00000334554 ZDHHC8 Q9ULC8 Palmitoyltransferase ZDHHC8 chr22 GO:0007610 Not Cancer Driver No 99 0.129 490 69 0.141 0
ZFHX2 ZFHX2 Q9C0A1 Zinc finger homeobox protein 2 chr14 GO:0007610 Not Cancer Driver No 52 0.02 1914 43 0.022 1
ZFY_ENST00000155093 ZFY P08048 Zinc finger Y-chromosomal protein chrY GO:0007610 Not Cancer Driver No 29 0.036 357 8 0.022 0
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 GO:0007610 Not Cancer Driver No 187 0.418 246 113 0.459 1
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0007610 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0007610 Not Cancer Driver No 43 0.111 312 34 0.109 0