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Total number of protein in "GO:0007420" GO term:  237

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
AATK AATK Q6ZMQ8 Serine/threonine-protein kinase LMTK1 chr17 GO:0007420 Not Cancer Driver No 108 0.079 912 75 0.082 0
ABCB6 ABCB6 Q9NP58 ATP-binding cassette sub-family B member 6 chr2 GO:0007420 Not Cancer Driver No 87 0.103 27 1 0.037 11
ACAT1 ACAT1 P24752 Acetyl-CoA acetyltransferase, mitochondrial chr11 GO:0007420 Not Cancer Driver No 45 0.105 32 1 0.031 10
ACE ACE P12821 Angiotensin-converting enzyme chr17 GO:0007420 Not Cancer Driver No 201 0.154 86 8 0.093 0
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0007420 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0007420 Not Cancer Driver No 64 0.092 67 4 0.06 9
ADGRL2_ENST00000370728 ADGRL2 O95490 Adhesion G protein-coupled receptor L2 chr1 GO:0007420 Not Cancer Driver No 373 0.256 452 122 0.27 0
ADGRL3 ADGRL3 Q9HAR2 Adhesion G protein-coupled receptor L3 chr4 GO:0007420 Not Cancer Driver No 440 0.304 517 130 0.251 0
AFF2 AFF2 P51816 AF4/FMR2 family member 2 chrX GO:0007420 Not Cancer Driver No 409 0.312 1003 314 0.313 0
AGTR2 AGTR2 P50052 Type-2 angiotensin II receptor chrX GO:0007420 Not Cancer Driver No 98 0.27 0 0 0.0 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0007420 Not Cancer Driver No 46 0.093 85 7 0.082 0
AMIGO2_ENST00000429635 AMIGO2 Q86SJ2 Amphoterin-induced protein 2 chr12 GO:0007420 Not Cancer Driver No 81 0.155 44 6 0.136 0
AMIGO3 AMIGO3 Q86WK7 Amphoterin-induced protein 3 chr3 GO:0007420 Not Cancer Driver No 69 0.137 60 7 0.117 0
APOD APOD P05090 Apolipoprotein D chr3 GO:0007420 Not Cancer Driver No 34 0.18 13 2 0.154 0
ARNT2 ARNT2 Q9HBZ2 Aryl hydrocarbon receptor nuclear translocator 2 chr15 GO:0007420 Not Cancer Driver No 100 0.139 448 61 0.136 0
ARRB2_ENST00000269260 ARRB2 P32121 Beta-arrestin-2 chr17 GO:0007420 Not Cancer Driver No 46 0.112 122 22 0.18 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0007420 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP2B1_ENST00000261173 ATP2B1 P20020 Plasma membrane calcium-transporting ATPase 1 chr12 GO:0007420 Not Cancer Driver No 143 0.117 293 42 0.143 0
ATP2B2 ATP2B2 Q01814 Plasma membrane calcium-transporting ATPase 2 chr3 GO:0007420 Not Cancer Driver No 248 0.2 360 82 0.228 0
ATP6V0D1 ATP6V0D1 P61421 V-type proton ATPase subunit d 1 chr16 GO:0007420 Not Cancer Driver No 40 0.114 0 0 0.0 0
ATXN1 ATXN1 P54253 Ataxin-1 chr6 GO:0007420 Not Cancer Driver No 193 0.237 604 168 0.278 0
ATXN1L ATXN1L P0C7T5 Ataxin-1-like chr16 GO:0007420 Not Cancer Driver No 30 0.044 476 19 0.04 0
B3GNT5_ENST00000460419 B3GNT5 Q9BYG0 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase chr3 GO:0007420 Not Cancer Driver No 45 0.119 0 0 0.0 0
BAG3 BAG3 O95817 BAG family molecular chaperone regulator 3 chr10 GO:0007420 Not Cancer Driver No 57 0.099 571 57 0.1 7
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0007420 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0007420 Not Cancer Driver No 85 0.154 330 52 0.158 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0007420 Not Cancer Driver No 38 0.18 58 9 0.155 0
BBS7 BBS7 Q8IWZ6 Bardet-Biedl syndrome 7 protein chr4 GO:0007420 Not Cancer Driver No 99 0.138 56 8 0.143 4
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0007420 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L2 BCL2L2 Q92843 Bcl-2-like protein 2 chr14 GO:0007420 Not Cancer Driver No 22 0.114 34 6 0.176 0
BCR BCR P11274 Breakpoint cluster region protein chr22 GO:0007420 Census, Compendium Yes 146 0.115 603 69 0.114 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0007420 Not Cancer Driver No 7 0.033 0 0 0.0 0
BPTF_ENST00000321892 BPTF Q12830 Nucleosome-remodeling factor subunit BPTF chr17 GO:0007420 Not Cancer Driver No 309 0.101 2187 218 0.1 2
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0007420 Census, Compendium Yes 457 0.134 1542 225 0.146 46
C2CD3 C2CD3 Q4AC94 C2 domain-containing protein 3 chr11 GO:0007420 Not Cancer Driver No 249 0.106 1104 106 0.096 1
CA10_ENST00000285273 CA10 Q9NS85 Carbonic anhydrase-related protein 10 chr17 GO:0007420 Not Cancer Driver No 103 0.314 9 1 0.111 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0007420 Not Cancer Driver No 106 0.24 103 28 0.272 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0007420 Not Cancer Driver No 63 0.139 42 12 0.286 0
CCDC39 CCDC39 Q9UFE4 Coiled-coil domain-containing protein 39 chr3 GO:0007420 Not Cancer Driver No 204 0.217 497 89 0.179 0
CCIN CCIN Q13939 Calicin chr9 GO:0007420 Not Cancer Driver No 100 0.17 2 1 0.5 0
CCNG1_ENST00000393929 CCNG1 P51959 Cyclin-G1 chr5 GO:0007420 Not Cancer Driver No 25 0.085 0 0 0.0 0
CDH2 CDH2 P19022 Cadherin-2 chr18 GO:0007420 Not Cancer Driver No 238 0.263 461 130 0.282 7
CDH22 CDH22 Q9UJ99 Cadherin-22 chr20 GO:0007420 Not Cancer Driver No 143 0.173 409 59 0.144 0
CDK5R1 CDK5R1 Q15078 Cyclin-dependent kinase 5 activator 1 chr17 GO:0007420 Not Cancer Driver No 35 0.114 103 16 0.155 0
CDK5R2 CDK5R2 Q13319 Cyclin-dependent kinase 5 activator 2 chr2 GO:0007420 Not Cancer Driver No 14 0.038 204 5 0.025 0
CDK5RAP1_ENST00000357886 CDK5RAP1 Q96SZ6 Mitochondrial tRNA methylthiotransferase CDK5RAP1 chr20 GO:0007420 Not Cancer Driver No 73 0.121 95 12 0.126 0
CDK5RAP2 CDK5RAP2 Q96SN8 CDK5 regulatory subunit-associated protein 2 chr9 GO:0007420 Not Cancer Driver No 217 0.115 1136 128 0.113 0
CDK5RAP3_ENST00000338399 CDK5RAP3 Q96JB5 CDK5 regulatory subunit-associated protein 3 chr17 GO:0007420 Not Cancer Driver No 50 0.099 99 20 0.202 0
CFAP43 CFAP43 Q8NDM7 Cilia- and flagella-associated protein 43 chr10 GO:0007420 Not Cancer Driver No 252 0.151 203 30 0.148 0
CHD8_ENST00000643469 CHD8 Q9HCK8 Chromodomain-helicase-DNA-binding protein 8 chr14 GO:0007420 Not Cancer Driver No 328 0.127 1411 148 0.105 0
CIC CIC Q96RK0 Protein capicua homolog chr19 GO:0007420 Census, Compendium Yes 276 0.172 1550 266 0.172 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0007420 Not Cancer Driver No 24 0.124 166 21 0.127 0
CLN5_ENST00000377453 CLN5 O75503 Ceroid-lipofuscinosis neuronal protein 5 chr13 GO:0007420 Not Cancer Driver No 39 0.109 16 1 0.062 12
CNTN1 CNTN1 Q12860 Contactin-1 chr12 GO:0007420 Not Cancer Driver No 265 0.26 220 50 0.227 0
CNTN4_ENST00000418658 CNTN4 Q8IWV2 Contactin-4 chr3 GO:0007420 Not Cancer Driver No 300 0.292 301 84 0.279 0
CNTN5_ENST00000528682 CNTN5 O94779 Contactin-5 chr11 GO:0007420 Not Cancer Driver No 380 0.345 290 74 0.255 0
CNTNAP2 CNTNAP2 Q9UHC6 Contactin-associated protein-like 2 chr7 GO:0007420 Census Yes 570 0.428 161 82 0.509 0
COL4A1 COL4A1 P02462 Collagen alpha-1(IV) chain chr13 GO:0007420 Not Cancer Driver No 349 0.209 1457 310 0.213 32
CSK_ENST00000439220 CSK P41240 Tyrosine-protein kinase CSK chr15 GO:0007420 Not Cancer Driver No 41 0.091 18 1 0.056 0
CTNND1 CTNND1 O60716 Catenin delta-1 chr11 GO:0007420 Census Yes 154 0.159 570 83 0.146 0
CTNS_ENST00000046640 CTNS O60931 Cystinosin chr17 GO:0007420 Not Cancer Driver No 34 0.093 0 0 0.0 31
CTTNBP2 CTTNBP2 Q8WZ74 Cortactin-binding protein 2 chr7 GO:0007420 Not Cancer Driver No 247 0.149 864 137 0.159 0
CX3CR1_ENST00000542107 CX3CR1 P49238 CX3C chemokine receptor 1 chr3 GO:0007420 Not Cancer Driver No 80 0.225 0 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0007420 Census, Compendium Yes 62 0.176 5 1 0.2 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0007420 Not Cancer Driver No 20 0.086 87 9 0.103 0
DHX37 DHX37 Q8IY37 Probable ATP-dependent RNA helicase DHX37 chr12 GO:0007420 Not Cancer Driver No 165 0.143 433 66 0.152 5
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0007420 Not Cancer Driver No 46 0.14 262 38 0.145 0
DMBX1_ENST00000371956 DMBX1 Q8NFW5 Diencephalon/mesencephalon homeobox protein 1 chr1 GO:0007420 Not Cancer Driver No 93 0.243 272 69 0.254 0
DNAJC30 DNAJC30 Q96LL9 DnaJ homolog subfamily C member 30, mitochondrial chr7 GO:0007420 Not Cancer Driver No 25 0.111 83 7 0.084 3
DPYSL2_ENST00000311151 DPYSL2 Q16555 Dihydropyrimidinase-related protein 2 chr8 GO:0007420 Not Cancer Driver No 86 0.15 146 32 0.219 0
DSCAML1 DSCAML1 Q8TD84 Down syndrome cell adhesion molecule-like protein 1 chr11 GO:0007420 Not Cancer Driver No 419 0.204 739 136 0.184 0
DTNBP1 DTNBP1 Q96EV8 Dysbindin chr6 GO:0007420 Not Cancer Driver No 49 0.14 210 25 0.119 0
EEF1AKMT4-ECE2 EEF1AKMT4-ECE2 P0DPD8 EEF1AKMT4-ECE2 readthrough transcript protein chr3 GO:0007420 Not Cancer Driver No 186 0.211 100 28 0.28 0
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0007420 Compendium Yes 90 0.189 352 59 0.168 11
EML1_ENST00000262233 EML1 O00423 Echinoderm microtubule-associated protein-like 1 chr14 GO:0007420 Not Cancer Driver No 146 0.179 205 31 0.151 2
EMX1 EMX1 Q04741 Homeobox protein EMX1 chr2 GO:0007420 Not Cancer Driver No 26 0.09 162 20 0.123 0
EMX2 EMX2 Q04743 Homeobox protein EMX2 chr10 GO:0007420 Not Cancer Driver No 34 0.135 147 21 0.143 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0007420 Not Cancer Driver No 82 0.12 436 50 0.115 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0007420 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPOR EPOR P19235 Erythropoietin receptor chr19 GO:0007420 Not Cancer Driver No 41 0.081 120 11 0.092 1
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 GO:0007420 Not Cancer Driver No 132 0.27 322 79 0.245 2
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0007420 Not Cancer Driver No 25 0.059 279 18 0.065 0
FPGS FPGS Q05932 Folylpolyglutamate synthase, mitochondrial chr9 GO:0007420 Not Cancer Driver No 68 0.116 141 18 0.128 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0007420 Not Cancer Driver No 146 0.316 55 14 0.255 3
GAS8 GAS8 O95995 Dynein regulatory complex subunit 4 chr16 GO:0007420 Not Cancer Driver No 54 0.113 232 29 0.125 1
GIT1_ENST00000225394 GIT1 Q9Y2X7 ARF GTPase-activating protein GIT1 chr17 GO:0007420 Not Cancer Driver No 67 0.088 434 42 0.097 0
GJC2 GJC2 Q5T442 Gap junction gamma-2 protein chr1 GO:0007420 Not Cancer Driver No 33 0.075 225 10 0.044 6
GNAI3 GNAI3 P08754 Guanine nucleotide-binding protein G(i) subunit alpha-3 chr1 GO:0007420 Not Cancer Driver No 42 0.119 11 0 0.0 1
GRHL2 GRHL2 Q6ISB3 Grainyhead-like protein 2 homolog chr8 GO:0007420 Not Cancer Driver No 95 0.152 258 43 0.167 2
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0007420 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0007420 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 GO:0007420 Not Cancer Driver No 413 0.278 426 147 0.345 11
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 GO:0007420 Not Cancer Driver No 111 0.09 276 6 0.022 0
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 GO:0007420 Not Cancer Driver No 125 0.094 467 15 0.032 1
H2AFY2 MACROH2A2 Q9P0M6 Core histone macro-H2A.2 chr10 GO:0007420 Not Cancer Driver No 59 0.159 171 32 0.187 0
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0007420 Not Cancer Driver No 97 0.145 454 60 0.132 0
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0007420 Not Cancer Driver No 1 0.006 73 0 0.0 0
HESX1 HESX1 Q9UBX0 Homeobox expressed in ES cells 1 chr3 GO:0007420 Not Cancer Driver No 32 0.173 59 9 0.153 6
HMGCS2 HMGCS2 P54868 Hydroxymethylglutaryl-CoA synthase, mitochondrial chr1 GO:0007420 Not Cancer Driver No 92 0.181 29 4 0.138 19
HMX2 HMX2 A2RU54 Homeobox protein HMX2 chr10 GO:0007420 Not Cancer Driver No 36 0.132 169 21 0.124 0
HMX3 HMX3 A6NHT5 Homeobox protein HMX3 chr10 GO:0007420 Not Cancer Driver No 28 0.078 240 17 0.071 0
HPCA HPCA P84074 Neuron-specific calcium-binding protein hippocalcin chr1 GO:0007420 Not Cancer Driver No 24 0.124 42 4 0.095 3
HSPG2 HSPG2 P98160 Basement membrane-specific heparan sulfate proteoglycan core protein chr1 GO:0007420 Compendium Yes 506 0.115 1709 194 0.114 1
ID1 ID1 P41134 DNA-binding protein inhibitor ID-1 chr20 GO:0007420 Not Cancer Driver No 20 0.129 17 6 0.353 0
IER3IP1 IER3IP1 Q9Y5U9 Immediate early response 3-interacting protein 1 chr18 GO:0007420 Not Cancer Driver No 3 0.037 0 0 0.0 2
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0007420 Not Cancer Driver No 219 0.125 96 10 0.104 8
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 GO:0007420 Not Cancer Driver No 36 0.206 29 7 0.241 0
IRS2 IRS2 Q9Y4H2 Insulin receptor substrate 2 chr13 GO:0007420 Not Cancer Driver No 69 0.052 1112 57 0.051 0
ITGA8 ITGA8 P53708 Integrin alpha-8 chr10 GO:0007420 Not Cancer Driver No 292 0.275 114 26 0.228 1
JHY JHY Q6NUN7 Jhy protein homolog chr11 GO:0007420 Not Cancer Driver No 142 0.183 748 130 0.174 0
KCNK3 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 GO:0007420 Not Cancer Driver No 54 0.137 60 7 0.117 6
KLHL17 KLHL17 Q6TDP4 Kelch-like protein 17 chr1 GO:0007420 Not Cancer Driver No 60 0.093 135 5 0.037 0
MACO1 MACO1 Q8N5G2 Macoilin chr1 GO:0007420 Not Cancer Driver No 79 0.119 407 52 0.128 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0007420 Not Cancer Driver No 118 0.111 527 48 0.091 0
MAST1 MAST1 Q9Y2H9 Microtubule-associated serine/threonine-protein kinase 1 chr19 GO:0007420 Not Cancer Driver No 204 0.13 1078 119 0.11 1
MBD3 MBD3 O95983 Methyl-CpG-binding domain protein 3 chr19 GO:0007420 Not Cancer Driver No 50 0.172 246 46 0.187 0
MDGA1 MDGA1 Q8NFP4 MAM domain-containing glycosylphosphatidylinositol anchor protein 1 chr6 GO:0007420 Not Cancer Driver No 148 0.155 312 51 0.163 0
MED1 MED1 Q15648 Mediator of RNA polymerase II transcription subunit 1 chr17 GO:0007420 Not Cancer Driver No 162 0.102 1104 117 0.106 0
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:0007420 Not Cancer Driver No 89 0.228 267 62 0.232 0
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 GO:0007420 Not Cancer Driver No 94 0.197 358 76 0.212 0
MEIS3_ENST00000558555 MEIS3 Q99687 Homeobox protein Meis3 chr19 GO:0007420 Not Cancer Driver No 54 0.144 247 43 0.174 0
MEN1 MEN1 O00255 Menin chr11 GO:0007420 Census, Compendium Yes 73 0.119 228 15 0.066 90
MFSD2A MFSD2A Q8NA29 Sodium-dependent lysophosphatidylcholine symporter 1 chr1 GO:0007420 Not Cancer Driver No 61 0.112 36 4 0.111 7
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0007420 Not Cancer Driver No 113 0.085 740 56 0.076 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0007420 Not Cancer Driver No 7 0.103 0 0 0.0 0
NAPA NAPA P54920 Alpha-soluble NSF attachment protein chr19 GO:0007420 Not Cancer Driver No 33 0.112 11 0 0.0 0
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 GO:0007420 Not Cancer Driver No 242 0.117 1941 219 0.113 0
NDRG4_ENST00000570248 NDRG4 Q9ULP0 Protein NDRG4 chr16 GO:0007420 Not Cancer Driver No 44 0.125 90 11 0.122 0
NDUFS4 NDUFS4 O43181 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial chr5 GO:0007420 Not Cancer Driver No 26 0.149 92 17 0.185 1
NEGR1 NEGR1 Q7Z3B1 Neuronal growth regulator 1 chr1 GO:0007420 Not Cancer Driver No 90 0.254 61 25 0.41 0
NES NES P48681 Nestin chr1 GO:0007420 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NEURL1 NEURL1 O76050 E3 ubiquitin-protein ligase NEURL1 chr10 GO:0007420 Not Cancer Driver No 62 0.108 153 11 0.072 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0007420 Census, Compendium Yes 375 0.132 406 47 0.116 85
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:0007420 Census Yes 63 0.15 254 36 0.142 3
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0007420 Compendium Yes 353 0.126 1528 184 0.12 37
NKX2-1_ENST00000518149 NKX2-1 P43699 Homeobox protein Nkx-2.1 chr14 GO:0007420 Census, Compendium Yes 41 0.111 334 39 0.117 7
NKX2-2 NKX2-2 O95096 Homeobox protein Nkx-2.2 chr20 GO:0007420 Not Cancer Driver No 84 0.308 206 65 0.316 0
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0007420 Not Cancer Driver No 91 0.109 300 19 0.063 0
NNAT NNAT Q16517 Neuronatin chr20 GO:0007420 Not Cancer Driver No 9 0.111 8 0 0.0 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0007420 Not Cancer Driver No 40 0.115 34 8 0.235 4
NRCAM_ENST00000425651 NRCAM Q92823 Neuronal cell adhesion molecule chr7 GO:0007420 Not Cancer Driver No 210 0.161 471 75 0.159 0
OXCT1 OXCT1 P55809 Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial chr5 GO:0007420 Not Cancer Driver No 80 0.154 39 5 0.128 11
PAFAH1B2 PAFAH1B2 P68402 Platelet-activating factor acetylhydrolase IB subunit alpha2 chr11 GO:0007420 Census Yes 25 0.109 43 1 0.023 0
PAFAH1B3_ENST00000262890 PAFAH1B3 Q15102 Platelet-activating factor acetylhydrolase IB subunit alpha1 chr19 GO:0007420 Not Cancer Driver No 15 0.065 76 3 0.039 0
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0007420 Census Yes 82 0.191 290 57 0.197 0
PBX2 PBX2 P40425 Pre-B-cell leukemia transcription factor 2 chr6 GO:0007420 Not Cancer Driver No 57 0.133 297 43 0.145 0
PBX3 PBX3 P40426 Pre-B-cell leukemia transcription factor 3 chr9 GO:0007420 Not Cancer Driver No 59 0.136 290 40 0.138 0
PBX4 PBX4 Q9BYU1 Pre-B-cell leukemia transcription factor 4 chr19 GO:0007420 Not Cancer Driver No 47 0.126 262 26 0.099 0
PCDH18 PCDH18 Q9HCL0 Protocadherin-18 chr4 GO:0007420 Not Cancer Driver No 357 0.315 447 139 0.311 0
PCDH19 PCDH19 Q8TAB3 Protocadherin-19 chrX GO:0007420 Not Cancer Driver No 264 0.23 495 132 0.267 35
PFKFB3_ENST00000379775 PFKFB3 Q16875 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 chr10 GO:0007420 Not Cancer Driver No 65 0.125 97 19 0.196 0
PHF8 PHF8 Q9UPP1 Histone lysine demethylase PHF8 chrX GO:0007420 Not Cancer Driver No 154 0.145 603 93 0.154 1
PHGDH_ENST00000641023 PHGDH O43175 D-3-phosphoglycerate dehydrogenase chr1 GO:0007420 Not Cancer Driver No 51 0.096 38 4 0.105 8
PITPNM1_ENST00000534749 PITPNM1 O00562 Membrane-associated phosphatidylinositol transfer protein 1 chr11 GO:0007420 Not Cancer Driver No 157 0.126 477 69 0.145 0
PLXNB2_ENST00000359337 PLXNB2 O15031 Plexin-B2 chr22 GO:0007420 Not Cancer Driver No 273 0.149 304 35 0.115 0
POMK POMK Q9H5K3 Protein O-mannose kinase chr8 GO:0007420 Not Cancer Driver No 53 0.151 30 9 0.3 3
POU3F4_ENST00000644024 POU3F4 P49335 POU domain, class 3, transcription factor 4 chrX GO:0007420 Not Cancer Driver No 115 0.319 263 80 0.304 5
PPP3CA PPP3CA Q08209 Protein phosphatase 3 catalytic subunit alpha chr4 GO:0007420 Compendium Yes 85 0.163 140 27 0.193 7
PPP3CC_ENST00000240139 PPP3CC P48454 Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform chr8 GO:0007420 Not Cancer Driver No 47 0.092 91 7 0.077 0
PPT1 PPT1 P50897 Palmitoyl-protein thioesterase 1 chr1 GO:0007420 Not Cancer Driver No 37 0.121 0 0 0.0 23
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0007420 Not Cancer Driver No 538 0.13 421 61 0.145 2
PROX1 PROX1 Q92786 Prospero homeobox protein 1 chr1 GO:0007420 Not Cancer Driver No 182 0.247 537 141 0.263 0
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0007420 Census, Compendium Yes 243 0.168 382 67 0.175 18
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0007420 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPRG PTPRG P23470 Receptor-type tyrosine-protein phosphatase gamma chr3 GO:0007420 Not Cancer Driver No 212 0.147 465 61 0.131 0
PYGO2 PYGO2 Q9BRQ0 Pygopus homolog 2 chr1 GO:0007420 Not Cancer Driver No 51 0.126 340 43 0.126 0
QARS QARS1 P47897 Glutamine--tRNA ligase chr3 GO:0007420 Not Cancer Driver No 101 0.13 106 16 0.151 4
RAB18_ENST00000356940 RAB18 Q9NP72 Ras-related protein Rab-18 chr10 GO:0007420 Not Cancer Driver No 19 0.092 18 2 0.111 1
RAB3GAP1_ENST00000264158 RAB3GAP1 Q15042 Rab3 GTPase-activating protein catalytic subunit chr2 GO:0007420 Not Cancer Driver No 123 0.125 294 32 0.109 2
RELN RELN P78509 Reelin chr7 GO:0007420 Not Cancer Driver No 761 0.22 107 19 0.178 7
RGS2 RGS2 P41220 Regulator of G-protein signaling 2 chr1 GO:0007420 Not Cancer Driver No 30 0.142 50 4 0.08 0
RGS4_ENST00000367909 RGS4 P49798 Regulator of G-protein signaling 4 chr1 GO:0007420 Not Cancer Driver No 68 0.332 5 4 0.8 0
RGS7_ENST00000366563 RGS7 P49802 Regulator of G-protein signaling 7 chr1 GO:0007420 Census, Compendium Yes 196 0.396 150 50 0.333 0
RIDA RIDA P52758 2-iminobutanoate/2-iminopropanoate deaminase chr8 GO:0007420 Not Cancer Driver No 20 0.146 3 0 0.0 0
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0007420 Census Yes 407 0.295 874 259 0.296 2
ROGDI ROGDI Q9GZN7 Protein rogdi homolog chr16 GO:0007420 Not Cancer Driver No 21 0.073 19 2 0.105 0
S1PR1 S1PR1 P21453 Sphingosine 1-phosphate receptor 1 chr1 GO:0007420 Not Cancer Driver No 86 0.225 29 6 0.207 0
SBK1 SBK1 Q52WX2 Serine/threonine-protein kinase SBK1 chr16 GO:0007420 Not Cancer Driver No 41 0.097 139 6 0.043 0
SCT SCT P09683 Secretin chr11 GO:0007420 Not Cancer Driver No 4 0.033 71 3 0.042 0
SCTR SCTR P47872 Secretin receptor chr2 GO:0007420 Not Cancer Driver No 74 0.168 18 1 0.056 0
SCYL2_ENST00000360820 SCYL2 Q6P3W7 SCY1-like protein 2 chr12 GO:0007420 Not Cancer Driver No 103 0.111 328 29 0.088 0
SELENOP_ENST00000506577 SELENOP P49908 Selenoprotein P chr5 GO:0007420 Not Cancer Driver No 67 0.176 154 19 0.123 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 GO:0007420 Not Cancer Driver No 223 0.131 1327 188 0.142 5
SHANK2_ENST00000601538 SHANK2 Q9UPX8 SH3 and multiple ankyrin repeat domains protein 2 chr11 GO:0007420 Not Cancer Driver No 303 0.164 1379 262 0.19 0
SHARPIN SHARPIN Q9H0F6 Sharpin chr8 GO:0007420 Not Cancer Driver No 34 0.088 237 16 0.068 0
SHROOM2 SHROOM2 Q13796 Protein Shroom2 chrX GO:0007420 Not Cancer Driver No 215 0.133 1381 188 0.136 0
SHROOM4 SHROOM4 Q9ULL8 Protein Shroom4 chrX GO:0007420 Not Cancer Driver No 242 0.162 1027 167 0.163 1
SIX3 SIX3 O95343 Homeobox protein SIX3 chr2 GO:0007420 Not Cancer Driver No 44 0.133 196 22 0.112 32
SLC17A7 SLC17A7 Q9P2U7 Vesicular glutamate transporter 1 chr19 GO:0007420 Not Cancer Driver No 79 0.141 80 21 0.263 0
SLC17A8 SLC17A8 Q8NDX2 Vesicular glutamate transporter 3 chr12 GO:0007420 Not Cancer Driver No 134 0.228 95 30 0.316 1
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0007420 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC23A1_ENST00000348729 SLC23A1 Q9UHI7 Solute carrier family 23 member 1 chr5 GO:0007420 Not Cancer Driver No 74 0.124 47 5 0.106 0
SLC38A3 SLC38A3 Q99624 Sodium-coupled neutral amino acid transporter 3 chr3 GO:0007420 Not Cancer Driver No 61 0.121 42 2 0.048 0
SLC6A11 SLC6A11 P48066 Sodium- and chloride-dependent GABA transporter 3 chr3 GO:0007420 Not Cancer Driver No 116 0.184 39 2 0.051 0
SLC6A17 SLC6A17 Q9H1V8 Sodium-dependent neutral amino acid transporter SLC6A17 chr1 GO:0007420 Not Cancer Driver No 119 0.164 67 10 0.149 2
SMARCA1_ENST00000371122 SMARCA1 P28370 Probable global transcription activator SNF2L1 chrX GO:0007420 Compendium Yes 143 0.136 309 41 0.133 0
SMG9 SMG9 Q9H0W8 Nonsense-mediated mRNA decay factor SMG9 chr19 GO:0007420 Not Cancer Driver No 43 0.083 256 23 0.09 0
SNRPB SNRPB P14678 Small nuclear ribonucleoprotein-associated proteins B and B' chr20 GO:0007420 Not Cancer Driver No 39 0.163 182 34 0.187 4
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 GO:0007420 Not Cancer Driver No 130 0.157 744 118 0.159 0
SPATA5 SPATA5 Q8NB90 ATPase family protein 2 homolog chr4 GO:0007420 Not Cancer Driver No 101 0.113 165 16 0.097 10
SPHK1_ENST00000545180 SPHK1 Q9NYA1 Sphingosine kinase 1 chr17 GO:0007420 Not Cancer Driver No 47 0.122 25 2 0.08 0
SPHK2 SPHK2 Q9NRA0 Sphingosine kinase 2 chr19 GO:0007420 Not Cancer Driver No 82 0.125 293 39 0.133 0
SRR SRR Q9GZT4 Serine racemase chr17 GO:0007420 Not Cancer Driver No 40 0.118 32 6 0.188 0
STK36_ENST00000440309 STK36 Q9NRP7 Serine/threonine-protein kinase 36 chr2 GO:0007420 Not Cancer Driver No 167 0.127 250 36 0.144 0
STXBP3 STXBP3 O00186 Syntaxin-binding protein 3 chr1 GO:0007420 Not Cancer Driver No 59 0.1 64 9 0.141 0
SYNJ1 SYNJ1 O43426 Synaptojanin-1 chr21 GO:0007420 Not Cancer Driver No 208 0.132 584 76 0.13 3
SYNJ2 SYNJ2 O15056 Synaptojanin-2 chr6 GO:0007420 Not Cancer Driver No 189 0.126 545 70 0.128 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0007420 Not Cancer Driver No 104 0.246 103 36 0.35 5
TBC1D23 TBC1D23 Q9NUY8 TBC1 domain family member 23 chr3 GO:0007420 Not Cancer Driver No 75 0.107 147 19 0.129 0
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 GO:0007420 Not Cancer Driver No 88 0.129 413 56 0.136 5
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0007420 Census, Compendium Yes 106 0.187 60 16 0.267 25
TMX2 TMX2 Q9Y320 Thioredoxin-related transmembrane protein 2 chr11 GO:0007420 Not Cancer Driver No 47 0.159 40 5 0.125 3
TSPAN2 TSPAN2 O60636 Tetraspanin-2 chr1 GO:0007420 Not Cancer Driver No 39 0.176 0 0 0.0 0
TTC25 ODAD4 Q96NG3 Outer dynein arm-docking complex subunit 4 chr17 GO:0007420 Not Cancer Driver No 62 0.092 264 25 0.095 0
TUBGCP2_ENST00000368563 TUBGCP2 Q9BSJ2 Gamma-tubulin complex component 2 chr10 GO:0007420 Not Cancer Driver No 124 0.137 93 16 0.172 0
TULP3_ENST00000448120 TULP3 O75386 Tubby-related protein 3 chr12 GO:0007420 Not Cancer Driver No 66 0.149 218 29 0.133 0
UBE2L3_ENST00000342192 UBE2L3 P68036 Ubiquitin-conjugating enzyme E2 L3 chr22 GO:0007420 Not Cancer Driver No 19 0.123 32 4 0.125 0
UBE3A UBE3A Q05086 Ubiquitin-protein ligase E3A chr15 GO:0007420 Not Cancer Driver No 141 0.161 136 22 0.162 0
UFC1 UFC1 Q9Y3C8 Ubiquitin-fold modifier-conjugating enzyme 1 chr1 GO:0007420 Not Cancer Driver No 24 0.144 10 0 0.0 2
UFM1_ENST00000239878 UFM1 P61960 Ubiquitin-fold modifier 1 chr13 GO:0007420 Not Cancer Driver No 10 0.118 0 0 0.0 1
UGP2 UGP2 Q16851 UTP--glucose-1-phosphate uridylyltransferase chr2 GO:0007420 Not Cancer Driver No 65 0.128 55 7 0.127 1
UNC5C UNC5C O95185 Netrin receptor UNC5C chr4 GO:0007420 Not Cancer Driver No 189 0.203 86 18 0.209 1
UTP3 UTP3 Q9NQZ2 Something about silencing protein 10 chr4 GO:0007420 Not Cancer Driver No 41 0.086 303 25 0.083 0
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0007420 Not Cancer Driver No 36 0.108 234 25 0.107 1
VCX VCX Q9H320 Variable charge X-linked protein 1 chrX GO:0007420 Not Cancer Driver No 50 0.243 206 50 0.243 0
VCX2 VCX2 Q9H322 Variable charge X-linked protein 2 chrX GO:0007420 Not Cancer Driver No 14 0.101 139 14 0.101 0
VCX3A VCX3A Q9NNX9 Variable charge X-linked protein 3 chrX GO:0007420 Not Cancer Driver No 24 0.129 186 24 0.129 0
VCX3B VCX3B Q9H321 Variable charge X-linked protein 3B chrX GO:0007420 Not Cancer Driver No 32 0.13 246 32 0.13 0
VCY VCY1B O14598 Testis-specific basic protein Y 1 chrY GO:0007420 Not Cancer Driver No 1 0.008 125 1 0.008 0
VCY1B VCY1B O14598 Testis-specific basic protein Y 1 chrY GO:0007420 Not Cancer Driver No 1 0.008 125 1 0.008 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0007420 Census, Compendium Yes 164 0.115 373 41 0.11 2
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0007420 Not Cancer Driver No 87 0.119 118 11 0.093 0
ZFHX2 ZFHX2 Q9C0A1 Zinc finger homeobox protein 2 chr14 GO:0007420 Not Cancer Driver No 52 0.02 1914 43 0.022 1
ZFHX3_ENST00000268489 ZFHX3 Q15911 Zinc finger homeobox protein 3 chr16 GO:0007420 Census, Compendium Yes 501 0.135 2555 337 0.132 0
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 GO:0007420 Not Cancer Driver No 187 0.418 246 113 0.459 1
ZIC2 ZIC2 O95409 Zinc finger protein ZIC 2 chr13 GO:0007420 Not Cancer Driver No 40 0.075 387 23 0.059 21
ZNF335 ZNF335 Q9H4Z2 Zinc finger protein 335 chr20 GO:0007420 Not Cancer Driver No 185 0.138 942 133 0.141 1