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Total number of protein in "GO:0007417" GO term:  140

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACAN ACAN P16112 Aggrecan core protein chr15 GO:0007417 Not Cancer Driver No 477 0.189 1868 323 0.173 2
ADAM22 ADAM22 Q9P0K1 Disintegrin and metalloproteinase domain-containing protein 22 chr7 GO:0007417 Not Cancer Driver No 189 0.209 222 43 0.194 0
ADAM23 ADAM23 O75077 Disintegrin and metalloproteinase domain-containing protein 23 chr2 GO:0007417 Not Cancer Driver No 175 0.21 162 26 0.16 0
ADGRA2 ADGRA2 Q96PE1 Adhesion G protein-coupled receptor A2 chr8 GO:0007417 Not Cancer Driver No 140 0.105 417 32 0.077 0
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0007417 Not Cancer Driver No 61 0.148 93 11 0.118 0
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0007417 Not Cancer Driver No 120 0.1 500 56 0.112 6
ALDH3A2_ENST00000579855 ALDH3A2 P51648 Aldehyde dehydrogenase family 3 member A2 chr17 GO:0007417 Not Cancer Driver No 47 0.097 5 2 0.4 26
ALDH5A1_ENST00000357578 ALDH5A1 P51649 Succinate-semialdehyde dehydrogenase, mitochondrial chr6 GO:0007417 Not Cancer Driver No 64 0.12 31 7 0.226 12
ANKLE2 ANKLE2 Q86XL3 Ankyrin repeat and LEM domain-containing protein 2 chr12 GO:0007417 Not Cancer Driver No 127 0.135 521 71 0.136 2
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0007417 Not Cancer Driver No 146 0.225 455 98 0.215 0
APLP2 APLP2 Q06481 Amyloid beta precursor like protein 2 chr11 GO:0007417 Not Cancer Driver No 96 0.126 393 48 0.122 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0007417 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARNT2 ARNT2 Q9HBZ2 Aryl hydrocarbon receptor nuclear translocator 2 chr15 GO:0007417 Not Cancer Driver No 100 0.139 448 61 0.136 0
ARSB ARSB P15848 Arylsulfatase B chr5 GO:0007417 Not Cancer Driver No 59 0.111 81 6 0.074 29
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0007417 Not Cancer Driver No 101 0.197 49 1 0.02 0
ATN1_ENST00000396684 ATN1 P54259 Atrophin-1 chr12 GO:0007417 Not Cancer Driver No 141 0.118 1176 139 0.118 6
ATOH1 ATOH1 Q92858 Transcription factor ATOH1 chr4 GO:0007417 Not Cancer Driver No 63 0.178 327 55 0.168 0
B3GNT5_ENST00000460419 B3GNT5 Q9BYG0 Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase chr3 GO:0007417 Not Cancer Driver No 45 0.119 0 0 0.0 0
BCAN BCAN Q96GW7 Brevican core protein chr1 GO:0007417 Not Cancer Driver No 198 0.217 341 75 0.22 0
BTD_ENST00000643237 BTD P43251 Biotinidase chr3 GO:0007417 Not Cancer Driver No 63 0.116 13 1 0.077 9
C2orf40 ECRG4 Q9H1Z8 Augurin chr2 GO:0007417 Not Cancer Driver No 37 0.25 23 11 0.478 0
CAPG_ENST00000409724 CAPG P40121 Macrophage-capping protein chr2 GO:0007417 Not Cancer Driver No 45 0.129 95 7 0.074 0
CELSR1 CELSR1 Q9NYQ6 Cadherin EGF LAG seven-pass G-type receptor 1 chr22 GO:0007417 Not Cancer Driver No 390 0.129 880 107 0.122 4
CHD7 CHD7 Q9P2D1 Chromodomain-helicase-DNA-binding protein 7 chr8 GO:0007417 Not Cancer Driver No 464 0.155 1872 299 0.16 50
CHST8_ENST00000434302 CHST8 Q9H2A9 Carbohydrate sulfotransferase 8 chr19 GO:0007417 Not Cancer Driver No 105 0.248 150 23 0.153 1
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0007417 Not Cancer Driver No 23 0.085 230 18 0.078 0
CNTN6_ENST00000350110 CNTN6 Q9UQ52 Contactin-6 chr3 GO:0007417 Not Cancer Driver No 330 0.321 173 59 0.341 0
COL2A1 COL2A1 P02458 Collagen alpha-1(II) chain chr12 GO:0007417 Census Yes 258 0.174 1215 207 0.17 64
COX7B COX7B P24311 Cytochrome c oxidase subunit 7B, mitochondrial chrX GO:0007417 Not Cancer Driver No 19 0.237 28 7 0.25 0
CYP26C1 CYP26C1 Q6V0L0 Cytochrome P450 26C1 chr10 GO:0007417 Not Cancer Driver No 32 0.061 56 6 0.107 0
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 GO:0007417 Not Cancer Driver No 209 0.282 252 77 0.306 0
DCX_ENST00000635795 DCX O43602 Neuronal migration protein doublecortin chrX GO:0007417 Not Cancer Driver No 118 0.323 155 49 0.316 50
DHX30 DHX30 Q7L2E3 ATP-dependent RNA helicase DHX30 chr3 GO:0007417 Not Cancer Driver No 165 0.138 260 40 0.154 6
DMBX1_ENST00000371956 DMBX1 Q8NFW5 Diencephalon/mesencephalon homeobox protein 1 chr1 GO:0007417 Not Cancer Driver No 93 0.243 272 69 0.254 0
DNER DNER Q8NFT8 Delta and Notch-like epidermal growth factor-related receptor chr2 GO:0007417 Not Cancer Driver No 162 0.22 106 26 0.245 0
DRP2 DRP2 Q13474 Dystrophin-related protein 2 chrX GO:0007417 Not Cancer Driver No 168 0.176 377 65 0.172 0
DSCAML1 DSCAML1 Q8TD84 Down syndrome cell adhesion molecule-like protein 1 chr11 GO:0007417 Not Cancer Driver No 419 0.204 739 136 0.184 0
EIF2B2 EIF2B2 P49770 Translation initiation factor eIF-2B subunit beta chr14 GO:0007417 Not Cancer Driver No 40 0.114 83 11 0.133 9
ELP3 ELP3 Q9H9T3 Elongator complex protein 3 chr8 GO:0007417 Not Cancer Driver No 60 0.11 19 4 0.211 0
EMX1 EMX1 Q04741 Homeobox protein EMX1 chr2 GO:0007417 Not Cancer Driver No 26 0.09 162 20 0.123 0
EMX2 EMX2 Q04743 Homeobox protein EMX2 chr10 GO:0007417 Not Cancer Driver No 34 0.135 147 21 0.143 0
GBA2 GBA2 Q9HCG7 Non-lysosomal glucosylceramidase chr9 GO:0007417 Not Cancer Driver No 96 0.104 157 12 0.076 3
GLIS2 GLIS2 Q9BZE0 Zinc finger protein GLIS2 chr16 GO:0007417 Not Cancer Driver No 42 0.08 300 25 0.083 0
GRHL3 GRHL3 Q8TE85 Grainyhead-like protein 3 homolog chr1 GO:0007417 Not Cancer Driver No 83 0.133 291 38 0.131 3
GRIK1_ENST00000399907 GRIK1 P39086 Glutamate receptor ionotropic, kainate 1 chr21 GO:0007417 Not Cancer Driver No 196 0.214 50 5 0.1 0
GSN GSN P06396 Gelsolin chr9 GO:0007417 Not Cancer Driver No 76 0.097 316 28 0.089 2
GSTP1_ENST00000642444 GSTP1 P09211 Glutathione S-transferase P chr11 GO:0007417 Not Cancer Driver No 32 0.152 0 0 0.0 0
GSX1 GSX1 Q9H4S2 GS homeobox 1 chr13 GO:0007417 Not Cancer Driver No 26 0.098 137 14 0.102 0
HAPLN1 HAPLN1 P10915 Hyaluronan and proteoglycan link protein 1 chr5 GO:0007417 Not Cancer Driver No 107 0.302 8 2 0.25 0
HAPLN2 HAPLN2 Q9GZV7 Hyaluronan and proteoglycan link protein 2 chr1 GO:0007417 Not Cancer Driver No 27 0.079 35 1 0.029 0
HAPLN3_ENST00000359595 HAPLN3 Q96S86 Hyaluronan and proteoglycan link protein 3 chr15 GO:0007417 Not Cancer Driver No 61 0.169 31 5 0.161 0
HAPLN4 HAPLN4 Q86UW8 Hyaluronan and proteoglycan link protein 4 chr19 GO:0007417 Not Cancer Driver No 60 0.149 54 16 0.296 0
HELT HELT A6NFD8 Hairy and enhancer of split-related protein HELT chr4 GO:0007417 Not Cancer Driver No 39 0.161 131 21 0.16 0
HPCAL4 HPCAL4 Q9UM19 Hippocalcin-like protein 4 chr1 GO:0007417 Not Cancer Driver No 35 0.183 15 1 0.067 0
ID3 ID3 Q02535 DNA-binding protein inhibitor ID-3 chr1 GO:0007417 Census, Compendium Yes 14 0.118 34 4 0.118 0
IL1RAPL2 IL1RAPL2 Q9NP60 X-linked interleukin-1 receptor accessory protein-like 2 chrX GO:0007417 Not Cancer Driver No 174 0.254 44 14 0.318 0
JARID2 JARID2 Q92833 Protein Jumonji chr6 GO:0007417 Not Cancer Driver No 190 0.152 724 113 0.156 0
JRKL JRKL Q9Y4A0 Jerky protein homolog-like chr11 GO:0007417 Not Cancer Driver No 52 0.099 68 8 0.118 0
KALRN_ENST00000360013 KALRN O60229 Kalirin chr3 GO:0007417 Not Cancer Driver No 544 0.182 732 128 0.175 0
KLK6 KLK6 Q92876 Kallikrein-6 chr19 GO:0007417 Not Cancer Driver No 62 0.254 28 12 0.429 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0007417 Not Cancer Driver No 134 0.147 63 10 0.159 2
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0007417 Not Cancer Driver No 21 0.137 0 0 0.0 0
MARCKS MARCKS P29966 Myristoylated alanine-rich C-kinase substrate chr6 GO:0007417 Not Cancer Driver No 14 0.042 328 14 0.043 0
MARCKSL1 MARCKSL1 P49006 MARCKS-related protein chr1 GO:0007417 Not Cancer Driver No 28 0.144 195 28 0.144 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0007417 Not Cancer Driver No 52 0.171 304 52 0.171 0
MNX1 MNX1 P50219 Motor neuron and pancreas homeobox protein 1 chr7 GO:0007417 Census Yes 34 0.085 297 30 0.101 11
MOG_ENST00000376917 MOG Q16653 Myelin-oligodendrocyte glycoprotein chr6 GO:0007417 Not Cancer Driver No 57 0.231 13 2 0.154 1
MTF1 MTF1 Q14872 Metal regulatory transcription factor 1 chr1 GO:0007417 Not Cancer Driver No 115 0.153 553 76 0.137 0
NCAN NCAN O14594 Neurocan core protein chr19 GO:0007417 Not Cancer Driver No 267 0.202 790 158 0.2 0
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0007417 Not Cancer Driver No 129 0.114 44 3 0.068 0
NDN NDN Q99608 Necdin chr15 GO:0007417 Not Cancer Driver No 123 0.383 117 42 0.359 0
NES NES P48681 Nestin chr1 GO:0007417 Not Cancer Driver No 271 0.167 1474 253 0.172 0
NEUROG3 NEUROG3 Q9Y4Z2 Neurogenin-3 chr10 GO:0007417 Not Cancer Driver No 53 0.248 156 34 0.218 2
NGFR NGFR P08138 Tumor necrosis factor receptor superfamily member 16 chr17 GO:0007417 Not Cancer Driver No 57 0.133 172 25 0.145 0
NHEJ1 NHEJ1 Q9H9Q4 Non-homologous end-joining factor 1 chr2 GO:0007417 Not Cancer Driver No 35 0.117 83 8 0.096 2
NHLH1 NHLH1 Q02575 Helix-loop-helix protein 1 chr1 GO:0007417 Not Cancer Driver No 30 0.226 90 22 0.244 0
NHLH2_ENST00000320238 NHLH2 Q02577 Helix-loop-helix protein 2 chr1 GO:0007417 Not Cancer Driver No 19 0.141 83 8 0.096 0
NMUR2 NMUR2 Q9GZQ4 Neuromedin-U receptor 2 chr5 GO:0007417 Not Cancer Driver No 139 0.335 5 1 0.2 0
NOTO NOTO A8MTQ0 Homeobox protein notochord chr2 GO:0007417 Not Cancer Driver No 15 0.06 116 6 0.052 0
NPAS1_ENST00000449844 NPAS1 Q99742 Neuronal PAS domain-containing protein 1 chr19 GO:0007417 Not Cancer Driver No 53 0.09 309 23 0.074 0
NPAS2 NPAS2 Q99743 Neuronal PAS domain-containing protein 2 chr2 GO:0007417 Not Cancer Driver No 114 0.138 465 65 0.14 0
NPTX1 NPTX1 Q15818 Neuronal pentraxin-1 chr17 GO:0007417 Not Cancer Driver No 63 0.146 185 24 0.13 0
NRCAM_ENST00000425651 NRCAM Q92823 Neuronal cell adhesion molecule chr7 GO:0007417 Not Cancer Driver No 210 0.161 471 75 0.159 0
PAM_ENST00000438793 PAM P19021 Peptidyl-glycine alpha-amidating monooxygenase chr5 GO:0007417 Not Cancer Driver No 129 0.133 254 37 0.146 0
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0007417 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0007417 Census Yes 84 0.187 291 55 0.189 4
PDGFC PDGFC Q9NRA1 Platelet-derived growth factor C chr4 GO:0007417 Not Cancer Driver No 86 0.249 53 12 0.226 0
PDX1 PDX1 P52945 Pancreas/duodenum homeobox protein 1 chr13 GO:0007417 Not Cancer Driver No 32 0.113 238 23 0.097 0
PIAS4 PIAS4 Q8N2W9 E3 SUMO-protein ligase PIAS4 chr19 GO:0007417 Not Cancer Driver No 58 0.114 142 23 0.162 0
POU3F3 POU3F3 P20264 POU domain, class 3, transcription factor 3 chr2 GO:0007417 Not Cancer Driver No 43 0.086 402 30 0.075 4
POU6F2 POU6F2 P78424 POU domain, class 6, transcription factor 2 chr7 GO:0007417 Not Cancer Driver No 165 0.239 571 144 0.252 1
PPP1R17 PPP1R17 O96001 Protein phosphatase 1 regulatory subunit 17 chr7 GO:0007417 Not Cancer Driver No 39 0.252 143 36 0.252 0
PRKN PRKN O60260 E3 ubiquitin-protein ligase parkin chr6 GO:0007417 Not Cancer Driver No 110 0.237 78 15 0.192 31
PROP1 PROP1 O75360 Homeobox protein prophet of Pit-1 chr5 GO:0007417 Not Cancer Driver No 35 0.155 194 32 0.165 7
PSPN PSPN O60542 Persephin chr19 GO:0007417 Not Cancer Driver No 9 0.058 13 1 0.077 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0007417 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0007417 Not Cancer Driver No 480 0.207 978 216 0.221 0
PTS PTS Q03393 6-pyruvoyl tetrahydrobiopterin synthase chr11 GO:0007417 Not Cancer Driver No 9 0.062 22 1 0.045 24
RELN RELN P78509 Reelin chr7 GO:0007417 Not Cancer Driver No 761 0.22 107 19 0.178 7
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0007417 Census Yes 407 0.295 874 259 0.296 2
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0007417 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0007417 Not Cancer Driver No 180 0.242 136 36 0.265 0
S100B S100B P04271 Protein S100-B chr21 GO:0007417 Not Cancer Driver No 17 0.185 13 1 0.077 0
SCIN SCIN Q9Y6U3 Scinderin chr7 GO:0007417 Not Cancer Driver No 100 0.14 170 35 0.206 0
SEMA6B SEMA6B Q9H3T3 Semaphorin-6B chr19 GO:0007417 Not Cancer Driver No 77 0.087 340 26 0.076 0
SERPINI1 SERPINI1 Q99574 Neuroserpin chr3 GO:0007417 Not Cancer Driver No 77 0.188 21 6 0.286 2
SH3GL1 SH3GL1 Q99961 Endophilin-A2 chr19 GO:0007417 Census Yes 45 0.122 245 33 0.135 0
SH3GL2 SH3GL2 Q99962 Endophilin-A1 chr9 GO:0007417 Not Cancer Driver No 76 0.216 214 50 0.234 0
SH3GL3_ENST00000427482 SH3GL3 Q99963 Endophilin-A3 chr15 GO:0007417 Not Cancer Driver No 88 0.254 83 23 0.277 0
SHC3 SHC3 Q92529 SHC-transforming protein 3 chr9 GO:0007417 Not Cancer Driver No 94 0.158 432 64 0.148 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0007417 Not Cancer Driver No 56 0.121 139 14 0.101 81
SLC2A1 SLC2A1 P11166 Solute carrier family 2, facilitated glucose transporter member 1 chr1 GO:0007417 Not Cancer Driver No 51 0.104 13 2 0.154 48
SMO SMO Q99835 Smoothened homolog chr7 GO:0007417 Census, Compendium Yes 112 0.142 241 27 0.112 1
SNTG2 SNTG2 Q9NY99 Gamma-2-syntrophin chr2 GO:0007417 Not Cancer Driver No 158 0.293 109 37 0.339 0
SOX3 SOX3 P41225 Transcription factor SOX-3 chrX GO:0007417 Not Cancer Driver No 63 0.141 341 61 0.179 0
SOX6_ENST00000528429 SOX6 P35712 Transcription factor SOX-6 chr11 GO:0007417 Not Cancer Driver No 130 0.157 744 118 0.159 0
SPINK5_ENST00000256084 SPINK5 Q9NQ38 Serine protease inhibitor Kazal-type 5 chr5 GO:0007417 Not Cancer Driver No 168 0.158 590 102 0.173 0
SPINK6_ENST00000621437 SPINK6 Q6UWN8 Serine protease inhibitor Kazal-type 6 chr5 GO:0007417 Not Cancer Driver No 17 0.212 0 0 0.0 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0007417 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0007417 Not Cancer Driver No 70 0.144 231 30 0.13 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0007417 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAGLN3 TAGLN3 Q9UI15 Transgelin-3 chr3 GO:0007417 Not Cancer Driver No 25 0.126 85 18 0.212 0
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0007417 Census, Compendium Yes 123 0.166 352 57 0.162 2
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0007417 Not Cancer Driver No 44 0.101 253 25 0.099 0
THOC6 THOC6 Q86W42 THO complex subunit 6 homolog chr16 GO:0007417 Not Cancer Driver No 49 0.144 16 4 0.25 1
TIMP4 TIMP4 Q99727 Metalloproteinase inhibitor 4 chr3 GO:0007417 Not Cancer Driver No 30 0.134 8 2 0.25 0
TLX3 TLX3 O43711 T-cell leukemia homeobox protein 3 chr5 GO:0007417 Census Yes 40 0.137 179 24 0.134 0
TPP1 TPP1 O14773 Tripeptidyl-peptidase 1 chr11 GO:0007417 Not Cancer Driver No 67 0.119 92 7 0.076 37
TRIO TRIO O75962 Triple functional domain protein chr5 GO:0007417 Not Cancer Driver No 400 0.129 1052 118 0.112 10
UGT8 UGT8 Q16880 2-hydroxyacylsphingosine 1-beta-galactosyltransferase chr4 GO:0007417 Not Cancer Driver No 107 0.198 18 2 0.111 0
VAX1 VAX1 Q5SQQ9 Ventral anterior homeobox 1 chr10 GO:0007417 Not Cancer Driver No 36 0.108 234 25 0.107 1
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0007417 Not Cancer Driver No 34 0.117 210 22 0.105 0
VCAN VCAN P13611 Versican core protein chr5 GO:0007417 Not Cancer Driver No 647 0.191 2643 483 0.183 0
WWP1 WWP1 Q9H0M0 NEDD4-like E3 ubiquitin-protein ligase WWP1 chr8 GO:0007417 Not Cancer Driver No 139 0.151 431 75 0.174 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0007417 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 GO:0007417 Not Cancer Driver No 187 0.418 246 113 0.459 1
ZIC2 ZIC2 O95409 Zinc finger protein ZIC 2 chr13 GO:0007417 Not Cancer Driver No 40 0.075 387 23 0.059 21
ZIC3 ZIC3 O60481 Zinc finger protein ZIC 3 chrX GO:0007417 Not Cancer Driver No 100 0.214 327 66 0.202 10
ZIC4_ENST00000383075 ZIC4 Q8N9L1 Zinc finger protein ZIC 4 chr3 GO:0007417 Not Cancer Driver No 179 0.536 163 102 0.626 0
ZIC5 ZIC5 Q96T25 Zinc finger protein ZIC 5 chr13 GO:0007417 Not Cancer Driver No 45 0.068 520 35 0.067 0