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Total number of protein in "GO:0007409" GO term:  122

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ACTBL2 ACTBL2 Q562R1 Beta-actin-like protein 2 chr5 GO:0007409 Not Cancer Driver No 73 0.194 29 5 0.172 0
ACTB_ENST00000646664 ACTB P60709 Actin, cytoplasmic 1 chr7 GO:0007409 Not Cancer Driver No 112 0.299 43 5 0.116 5
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0007409 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADCY1 ADCY1 Q08828 Adenylate cyclase type 1 chr7 GO:0007409 Not Cancer Driver No 244 0.218 99 19 0.192 0
ADGRB1_ENST00000323289 ADGRB1 O14514 Adhesion G protein-coupled receptor B1 chr8 GO:0007409 Compendium Yes 213 0.134 485 47 0.097 0
AFG3L2 AFG3L2 Q9Y4W6 AFG3-like protein 2 chr18 GO:0007409 Not Cancer Driver No 72 0.09 162 10 0.062 22
ALS2 ALS2 Q96Q42 Alsin chr2 GO:0007409 Not Cancer Driver No 194 0.117 353 36 0.102 0
AMIGO1_ENST00000369862 AMIGO1 Q86WK6 Amphoterin-induced protein 1 chr1 GO:0007409 Not Cancer Driver No 46 0.093 85 7 0.082 0
ANK3 ANK3 Q12955 Ankyrin-3 chr10 GO:0007409 Not Cancer Driver No 860 0.196 3054 579 0.19 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 GO:0007409 Not Cancer Driver No 105 0.148 399 58 0.145 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0007409 Not Cancer Driver No 146 0.225 455 98 0.215 0
APLP2 APLP2 Q06481 Amyloid beta precursor like protein 2 chr11 GO:0007409 Not Cancer Driver No 96 0.126 393 48 0.122 0
APP APP P05067 Amyloid-beta precursor protein chr21 GO:0007409 Not Cancer Driver No 128 0.166 418 71 0.17 17
ARHGAP35_ENST00000614079 ARHGAP35 Q9NRY4 Rho GTPase-activating protein 35 chr19 GO:0007409 Census, Compendium Yes 255 0.17 409 58 0.142 0
ATL1 ATL1 Q8WXF7 Atlastin-1 chr14 GO:0007409 Not Cancer Driver No 72 0.129 55 12 0.218 19
ATP8A2 ATP8A2 Q9NTI2 Phospholipid-transporting ATPase IB chr13 GO:0007409 Not Cancer Driver No 236 0.199 78 14 0.179 1
B4GALT5 B4GALT5 O43286 Beta-1,4-galactosyltransferase 5 chr20 GO:0007409 Not Cancer Driver No 53 0.137 20 1 0.05 0
B4GALT6 B4GALT6 Q9UBX8 Beta-1,4-galactosyltransferase 6 chr18 GO:0007409 Not Cancer Driver No 47 0.123 13 2 0.154 0
BAIAP2 BAIAP2 Q9UQB8 Brain-specific angiogenesis inhibitor 1-associated protein 2 chr17 GO:0007409 Not Cancer Driver No 85 0.154 330 52 0.158 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0007409 Census, Compendium Yes 24 0.1 72 5 0.069 0
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0007409 Not Cancer Driver No 131 0.168 459 78 0.17 0
BRSK2_ENST00000528841 BRSK2 Q8IWQ3 Serine/threonine-protein kinase BRSK2 chr11 GO:0007409 Not Cancer Driver No 90 0.122 321 39 0.121 0
C12orf57 C12orf57 Q99622 Protein C10 chr12 GO:0007409 Not Cancer Driver No 13 0.103 29 1 0.034 1
CCK CCK P06307 Cholecystokinin chr3 GO:0007409 Not Cancer Driver No 27 0.235 68 14 0.206 0
CCKAR CCKAR P32238 Cholecystokinin receptor type A chr4 GO:0007409 Not Cancer Driver No 107 0.25 49 14 0.286 0
CDH11 CDH11 P55287 Cadherin-11 chr16 GO:0007409 Census, Compendium Yes 264 0.332 399 127 0.318 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0007409 Not Cancer Driver No 48 0.164 5 1 0.2 0
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0007409 Not Cancer Driver No 92 0.183 23 2 0.087 2
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0007409 Not Cancer Driver No 36 0.086 71 2 0.028 0
CNTN4_ENST00000418658 CNTN4 Q8IWV2 Contactin-4 chr3 GO:0007409 Not Cancer Driver No 300 0.292 301 84 0.279 0
CNTNAP1 CNTNAP1 P78357 Contactin-associated protein 1 chr17 GO:0007409 Not Cancer Driver No 173 0.125 141 15 0.106 6
CREB1_ENST00000430624 CREB1 P16220 Cyclic AMP-responsive element-binding protein 1 chr2 GO:0007409 Census Yes 25 0.076 277 23 0.083 0
CTNNA2 CTNNA2 P26232 Catenin alpha-2 chr2 GO:0007409 Census Yes 387 0.406 307 130 0.423 0
DCC DCC P43146 Netrin receptor DCC chr18 GO:0007409 Census, Compendium Yes 530 0.366 631 215 0.341 2
DCLK1 DCLK1 O15075 Serine/threonine-protein kinase DCLK1 chr13 GO:0007409 Not Cancer Driver No 209 0.282 252 77 0.306 0
DOCK7_ENST00000635253 DOCK7 Q96N67 Dedicator of cytokinesis protein 7 chr1 GO:0007409 Not Cancer Driver No 262 0.122 454 53 0.117 0
DRAXIN DRAXIN Q8NBI3 Draxin chr1 GO:0007409 Not Cancer Driver No 61 0.175 249 48 0.193 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0007409 Not Cancer Driver No 127 0.287 124 45 0.363 0
DSCAML1 DSCAML1 Q8TD84 Down syndrome cell adhesion molecule-like protein 1 chr11 GO:0007409 Not Cancer Driver No 419 0.204 739 136 0.184 0
ECE1 ECE1 P42892 Endothelin-converting enzyme 1 chr1 GO:0007409 Not Cancer Driver No 118 0.153 99 26 0.263 1
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0007409 Not Cancer Driver No 37 0.175 97 20 0.206 3
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0007409 Not Cancer Driver No 62 0.145 21 6 0.286 2
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0007409 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB1 EPHB1 P54762 Ephrin type-B receptor 1 chr3 GO:0007409 Not Cancer Driver No 316 0.321 67 17 0.254 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0007409 Not Cancer Driver No 186 0.176 119 17 0.143 7
EPHB3 EPHB3 P54753 Ephrin type-B receptor 3 chr3 GO:0007409 Not Cancer Driver No 155 0.155 137 16 0.117 0
EPHB6_ENST00000422643 EPHB6 O15197 Ephrin type-B receptor 6 chr7 GO:0007409 Not Cancer Driver No 227 0.222 246 45 0.183 0
FBXO45 FBXO45 P0C2W1 F-box/SPRY domain-containing protein 1 chr3 GO:0007409 Not Cancer Driver No 28 0.098 10 0 0.0 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0007409 Census, Compendium Yes 238 0.29 228 44 0.193 72
FLOT1 FLOT1 O75955 Flotillin-1 chr6 GO:0007409 Not Cancer Driver No 43 0.101 122 15 0.123 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0007409 Not Cancer Driver No 287 0.181 1403 244 0.174 2
HSP90AA1_ENST00000216281 HSP90AA1 P07900 Heat shock protein HSP 90-alpha chr14 GO:0007409 Census, Compendium Yes 106 0.145 257 37 0.144 0
HSP90AB1 HSP90AB1 P08238 Heat shock protein HSP 90-beta chr6 GO:0007409 Census, Compendium Yes 100 0.138 254 43 0.169 0
IGF1R IGF1R P08069 Insulin-like growth factor 1 receptor chr15 GO:0007409 Not Cancer Driver No 183 0.134 265 37 0.14 6
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0007409 Not Cancer Driver No 85 0.244 180 41 0.228 0
ISL2 ISL2 Q96A47 Insulin gene enhancer protein ISL-2 chr15 GO:0007409 Not Cancer Driver No 42 0.117 167 16 0.096 0
ITGA4 ITGA4 P13612 Integrin alpha-4 chr2 GO:0007409 Not Cancer Driver No 254 0.246 97 27 0.278 0
KLF7 KLF7 O75840 Krueppel-like factor 7 chr2 GO:0007409 Not Cancer Driver No 46 0.152 72 7 0.097 0
LLGL1 LLGL1 Q15334 Lethal(2) giant larvae protein homolog 1 chr17 GO:0007409 Not Cancer Driver No 101 0.095 265 12 0.045 0
LMTK2 LMTK2 Q8IWU2 Serine/threonine-protein kinase LMTK2 chr7 GO:0007409 Not Cancer Driver No 211 0.14 1018 141 0.139 0
MAP1A MAP1A P78559 Microtubule-associated protein 1A chr15 GO:0007409 Not Cancer Driver No 369 0.132 2443 311 0.127 0
MAP1B MAP1B P46821 Microtubule-associated protein 1B chr5 GO:0007409 Not Cancer Driver No 332 0.135 1947 278 0.143 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0007409 Not Cancer Driver No 118 0.111 527 48 0.091 0
MYCBP2_ENST00000357337 MYCBP2 O75592 E3 ubiquitin-protein ligase MYCBP2 chr13 GO:0007409 Not Cancer Driver No 608 0.13 1398 189 0.135 0
NDEL1 NDEL1 Q9GZM8 Nuclear distribution protein nudE-like 1 chr17 GO:0007409 Not Cancer Driver No 32 0.093 202 16 0.079 0
NEFH NEFH P12036 Neurofilament heavy polypeptide chr22 GO:0007409 Compendium Yes 114 0.111 871 106 0.122 0
NFIB_ENST00000380959 NFIB O00712 Nuclear factor 1 B-type chr9 GO:0007409 Census Yes 63 0.15 254 36 0.142 3
NIN NIN Q8N4C6 Ninein chr14 GO:0007409 Census, Compendium Yes 239 0.114 1392 164 0.118 2
NKX2-8 NKX2-8 O15522 Homeobox protein Nkx-2.8 chr14 GO:0007409 Not Cancer Driver No 18 0.075 162 16 0.099 0
NPTX1 NPTX1 Q15818 Neuronal pentraxin-1 chr17 GO:0007409 Not Cancer Driver No 63 0.146 185 24 0.13 0
NR2E1_ENST00000368986 NR2E1 Q9Y466 Nuclear receptor subfamily 2 group E member 1 chr6 GO:0007409 Not Cancer Driver No 75 0.195 57 6 0.105 0
NR4A2_ENST00000409572 NR4A2 P43354 Nuclear receptor subfamily 4 group A member 2 chr2 GO:0007409 Not Cancer Driver No 110 0.184 261 38 0.146 0
NRCAM_ENST00000425651 NRCAM Q92823 Neuronal cell adhesion molecule chr7 GO:0007409 Not Cancer Driver No 210 0.161 471 75 0.159 0
NRP1 NRP1 O14786 Neuropilin-1 chr10 GO:0007409 Compendium Yes 146 0.158 211 31 0.147 0
NTNG1_ENST00000370073 NTNG1 Q9Y2I2 Netrin-G1 chr1 GO:0007409 Not Cancer Driver No 149 0.276 1 0 0.0 0
NTNG2 NTNG2 Q96CW9 Netrin-G2 chr9 GO:0007409 Not Cancer Driver No 91 0.172 8 4 0.5 7
NTRK1 NTRK1 P04629 High affinity nerve growth factor receptor chr1 GO:0007409 Census, Compendium Yes 168 0.211 57 8 0.14 25
NUMBL NUMBL Q9Y6R0 Numb-like protein chr19 GO:0007409 Not Cancer Driver No 42 0.069 467 23 0.049 0
NUMB_ENST00000355058 NUMB P49757 Protein numb homolog chr14 GO:0007409 Not Cancer Driver No 70 0.108 490 58 0.118 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0007409 Not Cancer Driver No 42 0.102 82 11 0.134 7
PAK3_ENST00000262836 PAK3 O75914 Serine/threonine-protein kinase PAK 3 chrX GO:0007409 Not Cancer Driver No 127 0.227 286 64 0.224 2
PARD3 PARD3 Q8TEW0 Partitioning defective 3 homolog chr10 GO:0007409 Not Cancer Driver No 200 0.147 1144 170 0.149 2
PARD6B PARD6B Q9BYG5 Partitioning defective 6 homolog beta chr20 GO:0007409 Not Cancer Driver No 50 0.134 166 23 0.139 0
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0007409 Not Cancer Driver No 62 0.149 296 48 0.162 23
PHOX2B PHOX2B Q99453 Paired mesoderm homeobox protein 2B chr4 GO:0007409 Census Yes 59 0.188 219 44 0.201 2
PICALM PICALM Q13492 Phosphatidylinositol-binding clathrin assembly protein chr11 GO:0007409 Census Yes 89 0.137 320 42 0.131 0
PLPPR4 PLPPR4 Q7Z2D5 Phospholipid phosphatase-related protein type 4 chr1 GO:0007409 Not Cancer Driver No 177 0.232 457 118 0.258 0
PLXNA4 PLXNA4 Q9HCM2 Plexin-A4 chr7 GO:0007409 Not Cancer Driver No 591 0.312 198 63 0.318 0
POU4F1 POU4F1 Q01851 POU domain, class 4, transcription factor 1 chr13 GO:0007409 Not Cancer Driver No 51 0.122 273 34 0.125 1
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0007409 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0007409 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPRZ1 PTPRZ1 P23471 Receptor-type tyrosine-protein phosphatase zeta chr7 GO:0007409 Not Cancer Driver No 480 0.207 978 216 0.221 0
RAB10 RAB10 P61026 Ras-related protein Rab-10 chr2 GO:0007409 Not Cancer Driver No 19 0.095 28 2 0.071 0
RAB3A RAB3A P20336 Ras-related protein Rab-3A chr19 GO:0007409 Not Cancer Driver No 25 0.114 43 4 0.093 0
RAB8A RAB8A P61006 Ras-related protein Rab-8A chr19 GO:0007409 Not Cancer Driver No 37 0.179 26 3 0.115 0
RTN4R RTN4R Q9BZR6 Reticulon-4 receptor chr22 GO:0007409 Not Cancer Driver No 38 0.08 148 17 0.115 5
RYK_ENST00000623711 RYK P34925 Tyrosine-protein kinase RYK chr3 GO:0007409 Not Cancer Driver No 55 0.091 85 4 0.047 0
S100A6_ENST00000496817 S100A6 P06703 Protein S100-A6 chr1 GO:0007409 Not Cancer Driver No 5 0.056 4 0 0.0 0
S100B S100B P04271 Protein S100-B chr21 GO:0007409 Not Cancer Driver No 17 0.185 13 1 0.077 0
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0007409 Not Cancer Driver No 195 0.253 164 46 0.28 10
SHTN1 SHTN1 A0MZ66 Shootin-1 chr10 GO:0007409 Census Yes 68 0.108 470 52 0.111 0
SLC25A46 SLC25A46 Q96AG3 Mitochondrial outer membrane protein SLC25A46 chr5 GO:0007409 Not Cancer Driver No 37 0.089 96 2 0.021 4
SLITRK1 SLITRK1 Q96PX8 SLIT and NTRK-like protein 1 chr13 GO:0007409 Not Cancer Driver No 299 0.43 126 64 0.508 0
SLITRK2 SLITRK2 Q9H156 SLIT and NTRK-like protein 2 chrX GO:0007409 Not Cancer Driver No 276 0.327 244 91 0.373 0
SLITRK3 SLITRK3 O94933 SLIT and NTRK-like protein 3 chr3 GO:0007409 Not Cancer Driver No 335 0.343 321 127 0.396 0
SLITRK4_ENST00000338017 SLITRK4 Q8IW52 SLIT and NTRK-like protein 4 chrX GO:0007409 Not Cancer Driver No 257 0.307 172 45 0.262 0
SLITRK5 SLITRK5 O94991 SLIT and NTRK-like protein 5 chr13 GO:0007409 Not Cancer Driver No 257 0.268 346 93 0.269 0
SLITRK6_ENST00000643778 SLITRK6 Q9H5Y7 SLIT and NTRK-like protein 6 chr13 GO:0007409 Not Cancer Driver No 244 0.29 225 53 0.236 0
SPAST SPAST Q9UBP0 Spastin chr2 GO:0007409 Not Cancer Driver No 73 0.119 270 25 0.093 77
SPTBN4_ENST00000598249 SPTBN4 Q9H254 Spectrin beta chain, non-erythrocytic 4 chr19 GO:0007409 Not Cancer Driver No 312 0.122 866 103 0.119 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0007409 Census, Compendium Yes 75 0.173 135 14 0.104 9
STMN1_ENST00000357865 STMN1 P16949 Stathmin chr1 GO:0007409 Not Cancer Driver No 15 0.101 149 15 0.101 0
SZT2_ENST00000634258 SZT2 Q5T011 KICSTOR complex protein SZT2 chr1 GO:0007409 Not Cancer Driver No 381 0.111 1292 161 0.125 1
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0007409 Not Cancer Driver No 191 0.155 666 102 0.153 0
TCTN1_ENST00000551590 TCTN1 Q2MV58 Tectonic-1 chr12 GO:0007409 Not Cancer Driver No 63 0.107 47 6 0.128 0
TNN TNN Q9UQP3 Tenascin-N chr1 GO:0007409 Not Cancer Driver No 426 0.328 637 231 0.363 0
TOP2B TOP2B Q02880 DNA topoisomerase 2-beta chr3 GO:0007409 Not Cancer Driver No 154 0.095 543 46 0.085 0
TRIM46 TRIM46 Q7Z4K8 Tripartite motif-containing protein 46 chr1 GO:0007409 Not Cancer Driver No 115 0.152 173 30 0.173 0
TSKU_ENST00000333090 TSKU Q8WUA8 Tsukushi chr11 GO:0007409 Not Cancer Driver No 53 0.15 44 6 0.136 0
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0007409 Not Cancer Driver No 34 0.117 210 22 0.105 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0007409 Not Cancer Driver No 93 0.266 18 9 0.5 4
ZDHHC17 ZDHHC17 Q8IUH5 Palmitoyltransferase ZDHHC17 chr12 GO:0007409 Not Cancer Driver No 84 0.133 49 9 0.184 0