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Total number of protein in "GO:0007389" GO term:  292

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABI1 ABI1 Q8IZP0 Abl interactor 1 chr10 GO:0007389 Census, Compendium Yes 55 0.108 360 39 0.108 0
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0007389 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACVR1_ENST00000434821 ACVR1 Q04771 Activin receptor type-1 chr2 GO:0007389 Census, Compendium Yes 78 0.153 21 8 0.381 8
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0007389 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADGRG1 ADGRG1 Q9Y653 Adhesion G-protein coupled receptor G1 chr16 GO:0007389 Not Cancer Driver No 64 0.092 67 4 0.06 9
AHI1_ENST00000457866 AHI1 Q8N157 Jouberin chr6 GO:0007389 Not Cancer Driver No 120 0.1 500 56 0.112 6
AIDA AIDA Q96BJ3 Axin interactor, dorsalization-associated protein chr1 GO:0007389 Not Cancer Driver No 36 0.118 87 9 0.103 0
ALDH1A2 ALDH1A2 O94788 Retinal dehydrogenase 2 chr15 GO:0007389 Not Cancer Driver No 100 0.193 56 13 0.232 0
ALX3 ALX3 O95076 Homeobox protein aristaless-like 3 chr1 GO:0007389 Not Cancer Driver No 37 0.108 303 33 0.109 4
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0007389 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APC2_ENST00000233607 APC2 O95996 Adenomatous polyposis coli protein 2 chr19 GO:0007389 Not Cancer Driver No 117 0.051 1725 78 0.045 0
ARL13B ARL13B Q3SXY8 ADP-ribosylation factor-like protein 13B chr3 GO:0007389 Not Cancer Driver No 62 0.145 251 40 0.159 3
ASPH ASPH Q12797 Aspartyl/asparaginyl beta-hydroxylase chr8 GO:0007389 Not Cancer Driver No 109 0.144 373 53 0.142 1
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0007389 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATP6AP2 ATP6AP2 O75787 Renin receptor chrX GO:0007389 Not Cancer Driver No 56 0.16 0 0 0.0 2
AURKA_ENST00000395915 AURKA O14965 Aurora kinase A chr20 GO:0007389 Not Cancer Driver No 36 0.089 178 21 0.118 0
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0007389 Census, Compendium Yes 120 0.139 619 88 0.142 4
AXIN2 AXIN2 Q9Y2T1 Axin-2 chr17 GO:0007389 Census, Compendium Yes 114 0.135 547 77 0.141 0
BASP1_ENST00000616743 BASP1 P80723 Brain acid soluble protein 1 chr5 GO:0007389 Not Cancer Driver No 39 0.172 227 39 0.172 0
BCOR BCOR Q6W2J9 BCL-6 corepressor chrX GO:0007389 Census, Compendium Yes 291 0.166 1285 226 0.176 1
BMI1 BMI1 P35226 Polycomb complex protein BMI-1 chr10 GO:0007389 Not Cancer Driver No 50 0.153 150 30 0.2 0
BMP1 BMP1 P13497 Bone morphogenetic protein 1 chr8 GO:0007389 Not Cancer Driver No 119 0.121 154 25 0.162 3
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0007389 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0007389 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP5 BMP5 P22003 Bone morphogenetic protein 5 chr6 GO:0007389 Census Yes 163 0.359 112 62 0.554 0
BMP7 BMP7 P18075 Bone morphogenetic protein 7 chr20 GO:0007389 Not Cancer Driver No 91 0.211 69 18 0.261 0
BMPR1A BMPR1A P36894 Bone morphogenetic protein receptor type-1A chr10 GO:0007389 Census, Compendium Yes 66 0.124 21 0 0.0 8
BMPR1B_ENST00000394931 BMPR1B O00238 Bone morphogenetic protein receptor type-1B chr4 GO:0007389 Not Cancer Driver No 84 0.167 64 12 0.188 5
C1QA C1QA P02745 Complement C1q subcomponent subunit A chr1 GO:0007389 Not Cancer Driver No 41 0.167 124 16 0.129 0
C2CD3 C2CD3 Q4AC94 C2 domain-containing protein 3 chr11 GO:0007389 Not Cancer Driver No 249 0.106 1104 106 0.096 1
C3 C3 P01024 Complement C3 chr19 GO:0007389 Not Cancer Driver No 337 0.203 287 50 0.174 12
CCDC103 CCDC103 Q8IW40 Coiled-coil domain-containing protein 103 chr17 GO:0007389 Not Cancer Driver No 22 0.091 78 8 0.103 0
CCDC39 CCDC39 Q9UFE4 Coiled-coil domain-containing protein 39 chr3 GO:0007389 Not Cancer Driver No 204 0.217 497 89 0.179 0
CCDC40 CCDC40 Q4G0X9 Coiled-coil domain-containing protein 40 chr17 GO:0007389 Not Cancer Driver No 201 0.176 672 123 0.183 0
CDX1 CDX1 P47902 Homeobox protein CDX-1 chr5 GO:0007389 Not Cancer Driver No 21 0.079 241 13 0.054 0
CDX2 CDX2 Q99626 Homeobox protein CDX-2 chr13 GO:0007389 Census, Compendium Yes 39 0.125 271 35 0.129 0
CDX4 CDX4 O14627 Homeobox protein CDX-4 chrX GO:0007389 Not Cancer Driver No 86 0.303 188 54 0.287 0
CELSR2 CELSR2 Q9HCU4 Cadherin EGF LAG seven-pass G-type receptor 2 chr1 GO:0007389 Not Cancer Driver No 348 0.119 990 115 0.116 0
CER1 CER1 O95813 Cerberus chr9 GO:0007389 Not Cancer Driver No 70 0.262 119 27 0.227 0
CFAP45 CFAP45 Q9UL16 Cilia- and flagella-associated protein 45 chr1 GO:0007389 Not Cancer Driver No 126 0.229 493 120 0.243 0
CFAP52 CFAP52 Q8N1V2 Cilia- and flagella-associated protein 52 chr17 GO:0007389 Not Cancer Driver No 107 0.173 4 0 0.0 0
CHSY1 CHSY1 Q86X52 Chondroitin sulfate synthase 1 chr15 GO:0007389 Not Cancer Driver No 95 0.118 137 10 0.073 1
CITED2_ENST00000367651 CITED2 Q99967 Cbp/p300-interacting transactivator 2 chr6 GO:0007389 Not Cancer Driver No 23 0.085 230 18 0.078 0
COBL_ENST00000265136 COBL O75128 Protein cordon-bleu chr7 GO:0007389 Not Cancer Driver No 233 0.185 1149 216 0.188 0
CRAMP1 CRAMP1 Q96RY5 Protein cramped-like chr16 GO:0007389 Not Cancer Driver No 120 0.095 991 94 0.095 0
CRB2 CRB2 Q5IJ48 Protein crumbs homolog 2 chr9 GO:0007389 Not Cancer Driver No 155 0.121 72 0 0.0 5
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0007389 Census, Compendium Yes 415 0.531 288 301 1.045 14
CYP26B1 CYP26B1 Q9NR63 Cytochrome P450 26B1 chr2 GO:0007389 Not Cancer Driver No 113 0.221 10 3 0.3 2
DAND5 DAND5 Q8N907 DAN domain family member 5 chr19 GO:0007389 Not Cancer Driver No 32 0.169 26 3 0.115 0
DCANP1 DCANP1 Q8TF63 Dendritic cell nuclear protein 1 chr5 GO:0007389 Not Cancer Driver No 44 0.18 159 35 0.22 0
DCHS1 DCHS1 Q96JQ0 Protocadherin-16 chr11 GO:0007389 Not Cancer Driver No 444 0.135 2197 317 0.144 3
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0007389 Census Yes 29 0.172 160 27 0.169 0
DISP1 DISP1 Q96F81 Protein dispatched homolog 1 chr1 GO:0007389 Not Cancer Driver No 212 0.139 252 35 0.139 0
DLL1 DLL1 O00548 Delta-like protein 1 chr6 GO:0007389 Not Cancer Driver No 115 0.159 145 24 0.166 1
DLL3 DLL3 Q9NYJ7 Delta-like protein 3 chr19 GO:0007389 Not Cancer Driver No 73 0.118 119 10 0.084 1
DLX1 DLX1 P56177 Homeobox protein DLX-1 chr2 GO:0007389 Not Cancer Driver No 25 0.098 183 21 0.115 0
DLX2 DLX2 Q07687 Homeobox protein DLX-2 chr2 GO:0007389 Not Cancer Driver No 46 0.14 262 38 0.145 0
DMRTA2_ENST00000418121 DMRTA2 Q96SC8 Doublesex- and mab-3-related transcription factor A2 chr1 GO:0007389 Not Cancer Driver No 25 0.046 325 19 0.058 0
DNAAF1 DNAAF1 Q8NEP3 Dynein axonemal assembly factor 1 chr16 GO:0007389 Not Cancer Driver No 107 0.148 513 71 0.138 1
DNAAF2 DNAAF2 Q9NVR5 Protein kintoun chr14 GO:0007389 Not Cancer Driver No 77 0.092 579 37 0.064 0
DNAH11 DNAH11 Q96DT5 Dynein axonemal heavy chain 11 chr7 GO:0007389 Not Cancer Driver No 885 0.196 221 36 0.163 3
DOP1B DOP1B Q9Y3R5 Protein dopey-2 chr21 GO:0007389 Not Cancer Driver No 295 0.128 450 71 0.158 0
DPCD DPCD Q9BVM2 Protein DPCD chr10 GO:0007389 Not Cancer Driver No 20 0.099 24 1 0.042 0
DSCAML1 DSCAML1 Q8TD84 Down syndrome cell adhesion molecule-like protein 1 chr11 GO:0007389 Not Cancer Driver No 419 0.204 739 136 0.184 0
DVL2 DVL2 O14641 Segment polarity protein dishevelled homolog DVL-2 chr17 GO:0007389 Not Cancer Driver No 96 0.13 514 64 0.125 0
DYNC2H1_ENST00000375735 DYNC2H1 Q8NCM8 Cytoplasmic dynein 2 heavy chain 1 chr11 GO:0007389 Not Cancer Driver No 510 0.118 282 15 0.053 34
DZIP1L DZIP1L Q8IYY4 Cilium assembly protein DZIP1L chr3 GO:0007389 Not Cancer Driver No 118 0.154 560 84 0.15 2
EDN1 EDN1 P05305 Endothelin-1 chr6 GO:0007389 Not Cancer Driver No 37 0.175 97 20 0.206 3
EFNB1 EFNB1 P98172 Ephrin-B1 chrX GO:0007389 Not Cancer Driver No 46 0.133 126 14 0.111 19
EGR2 EGR2 P11161 E3 SUMO-protein ligase EGR2 chr10 GO:0007389 Compendium Yes 90 0.189 352 59 0.168 11
EMX1 EMX1 Q04741 Homeobox protein EMX1 chr2 GO:0007389 Not Cancer Driver No 26 0.09 162 20 0.123 0
EMX2 EMX2 Q04743 Homeobox protein EMX2 chr10 GO:0007389 Not Cancer Driver No 34 0.135 147 21 0.143 0
EN1 EN1 Q05925 Homeobox protein engrailed-1 chr2 GO:0007389 Not Cancer Driver No 42 0.107 357 30 0.084 0
ENKUR ENKUR Q8TC29 Enkurin chr10 GO:0007389 Not Cancer Driver No 53 0.207 157 39 0.248 0
EOMES_ENST00000295743 EOMES O95936 Eomesodermin homolog chr3 GO:0007389 Not Cancer Driver No 82 0.12 436 50 0.115 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0007389 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPB41L5 EPB41L5 Q9HCM4 Band 4.1-like protein 5 chr2 GO:0007389 Not Cancer Driver No 97 0.132 312 45 0.144 0
ERBB4 ERBB4 Q15303 Receptor tyrosine-protein kinase erbB-4 chr2 GO:0007389 Census, Compendium Yes 428 0.327 323 116 0.359 2
EXT1 EXT1 Q16394 Exostosin-1 chr8 GO:0007389 Census Yes 107 0.143 58 7 0.121 12
EYA1_ENST00000647540 EYA1 Q99502 Eyes absent homolog 1 chr8 GO:0007389 Not Cancer Driver No 168 0.284 341 99 0.29 15
FAM208A_ENST00000355628 TASOR Q9UK61 Protein TASOR chr3 GO:0007389 Not Cancer Driver No 150 0.09 776 68 0.088 0
FBXL15 FBXL15 Q9H469 F-box/LRR-repeat protein 15 chr10 GO:0007389 Not Cancer Driver No 9 0.03 16 1 0.062 0
FEZF1 FEZF1 A0PJY2 Fez family zinc finger protein 1 chr7 GO:0007389 Not Cancer Driver No 77 0.162 151 27 0.179 1
FEZF2_ENST00000475839 FEZF2 Q8TBJ5 Fez family zinc finger protein 2 chr3 GO:0007389 Not Cancer Driver No 65 0.142 144 14 0.097 0
FGF10 FGF10 O15520 Fibroblast growth factor 10 chr5 GO:0007389 Not Cancer Driver No 56 0.269 34 11 0.324 2
FGF8_ENST00000344255 FGF8 P55075 Fibroblast growth factor 8 chr10 GO:0007389 Not Cancer Driver No 30 0.129 79 9 0.114 6
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0007389 Census, Compendium Yes 238 0.29 228 44 0.193 72
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 GO:0007389 Not Cancer Driver No 71 0.172 160 25 0.156 0
FOXA1 FOXA1 P55317 Hepatocyte nuclear factor 3-alpha chr14 GO:0007389 Census, Compendium Yes 100 0.212 295 53 0.18 0
FOXB1 FOXB1 Q99853 Forkhead box protein B1 chr15 GO:0007389 Not Cancer Driver No 31 0.095 114 5 0.044 0
FOXC1_ENST00000645831 FOXC1 Q12948 Forkhead box protein C1 chr6 GO:0007389 Not Cancer Driver No 33 0.06 411 24 0.058 32
FOXC2 FOXC2 Q99958 Forkhead box protein C2 chr16 GO:0007389 Not Cancer Driver No 63 0.126 369 33 0.089 1
FOXD1 FOXD1 Q16676 Forkhead box protein D1 chr5 GO:0007389 Not Cancer Driver No 10 0.022 259 5 0.019 0
FOXF1 FOXF1 Q12946 Forkhead box protein F1 chr16 GO:0007389 Not Cancer Driver No 56 0.148 194 20 0.103 20
FOXG1 FOXG1 P55316 Forkhead box protein G1 chr14 GO:0007389 Not Cancer Driver No 132 0.27 322 79 0.245 2
FOXH1 FOXH1 O75593 Forkhead box protein H1 chr8 GO:0007389 Not Cancer Driver No 47 0.129 215 25 0.116 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0007389 Not Cancer Driver No 25 0.059 279 18 0.065 0
FRS2 FRS2 Q8WU20 Fibroblast growth factor receptor substrate 2 chr12 GO:0007389 Not Cancer Driver No 69 0.136 415 58 0.14 0
FST FST P19883 Follistatin chr5 GO:0007389 Not Cancer Driver No 50 0.145 20 7 0.35 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0007389 Not Cancer Driver No 45 0.077 58 4 0.069 0
GATA4_ENST00000335135 GATA4 P43694 Transcription factor GATA-4 chr8 GO:0007389 Not Cancer Driver No 48 0.109 301 34 0.113 18
GDF11 GDF11 O95390 Growth/differentiation factor 11 chr12 GO:0007389 Not Cancer Driver No 40 0.098 109 7 0.064 1
GDF3 GDF3 Q9NR23 Growth/differentiation factor 3 chr12 GO:0007389 Not Cancer Driver No 79 0.217 3 3 1.0 5
GLI1 GLI1 P08151 Zinc finger protein GLI1 chr12 GO:0007389 Census, Compendium Yes 206 0.186 1015 184 0.181 0
GLI2_ENST00000361492 GLI2 P10070 Zinc finger protein GLI2 chr2 GO:0007389 Not Cancer Driver No 287 0.181 1403 244 0.174 2
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0007389 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GPC3_ENST00000370818 GPC3 P51654 Glypican-3 chrX GO:0007389 Census Yes 89 0.153 86 11 0.128 1
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0007389 Not Cancer Driver No 25 0.136 77 12 0.156 0
GREM2 GREM2 Q9H772 Gremlin-2 chr1 GO:0007389 Not Cancer Driver No 54 0.321 22 9 0.409 3
GRHL3 GRHL3 Q8TE85 Grainyhead-like protein 3 homolog chr1 GO:0007389 Not Cancer Driver No 83 0.133 291 38 0.131 3
GSC GSC P56915 Homeobox protein goosecoid chr14 GO:0007389 Not Cancer Driver No 17 0.066 109 11 0.101 0
GSX2 GSX2 Q9BZM3 GS homeobox 2 chr4 GO:0007389 Not Cancer Driver No 44 0.145 210 26 0.124 1
HES5 HES5 Q5TA89 Transcription factor HES-5 chr1 GO:0007389 Not Cancer Driver No 1 0.006 73 0 0.0 0
HES7_ENST00000317814 HES7 Q9BYE0 Transcription factor HES-7 chr17 GO:0007389 Not Cancer Driver No 7 0.031 166 5 0.03 3
HEY2 HEY2 Q9UBP5 Hairy/enhancer-of-split related with YRPW motif protein 2 chr6 GO:0007389 Not Cancer Driver No 64 0.19 179 26 0.145 0
HHIP HHIP Q96QV1 Hedgehog-interacting protein chr4 GO:0007389 Not Cancer Driver No 150 0.214 73 34 0.466 0
HOXA10 HOXA10 P31260 Homeobox protein Hox-A10 chr7 GO:0007389 Not Cancer Driver No 35 0.085 339 25 0.074 0
HOXA11 HOXA11 P31270 Homeobox protein Hox-A11 chr7 GO:0007389 Census, Compendium Yes 37 0.118 205 26 0.127 0
HOXA2 HOXA2 O43364 Homeobox protein Hox-A2 chr7 GO:0007389 Not Cancer Driver No 58 0.154 281 48 0.171 1
HOXA3_ENST00000396352 HOXA3 O43365 Homeobox protein Hox-A3 chr7 GO:0007389 Not Cancer Driver No 86 0.194 417 84 0.201 0
HOXA9 HOXA9 P31269 Homeobox protein Hox-A9 chr7 GO:0007389 Census Yes 46 0.169 187 35 0.187 0
HOXB1 HOXB1 P14653 Homeobox protein Hox-B1 chr17 GO:0007389 Not Cancer Driver No 71 0.236 276 68 0.246 1
HOXB2 HOXB2 P14652 Homeobox protein Hox-B2 chr17 GO:0007389 Not Cancer Driver No 47 0.132 269 35 0.13 0
HOXB9 HOXB9 P17482 Homeobox protein Hox-B9 chr17 GO:0007389 Not Cancer Driver No 28 0.112 191 27 0.141 0
HOXC10 HOXC10 Q9NYD6 Homeobox protein Hox-C10 chr12 GO:0007389 Not Cancer Driver No 62 0.181 266 48 0.18 0
HOXC11 HOXC11 O43248 Homeobox protein Hox-C11 chr12 GO:0007389 Census Yes 35 0.115 157 16 0.102 0
HOXC9 HOXC9 P31274 Homeobox protein Hox-C9 chr12 GO:0007389 Not Cancer Driver No 30 0.115 143 14 0.098 0
HOXD10 HOXD10 P28358 Homeobox protein Hox-D10 chr2 GO:0007389 Not Cancer Driver No 74 0.218 230 55 0.239 1
HOXD11 HOXD11 P31277 Homeobox protein Hox-D11 chr2 GO:0007389 Census Yes 32 0.095 219 14 0.064 0
HOXD12 HOXD12 P35452 Homeobox protein Hox-D12 chr2 GO:0007389 Not Cancer Driver No 42 0.156 128 15 0.117 0
HOXD8 HOXD8 P13378 Homeobox protein Hox-D8 chr2 GO:0007389 Not Cancer Driver No 31 0.107 199 24 0.121 0
HOXD9 HOXD9 P28356 Homeobox protein Hox-D9 chr2 GO:0007389 Not Cancer Driver No 47 0.134 276 30 0.109 0
HSPB11 HSPB11 Q9Y547 Intraflagellar transport protein 25 homolog chr1 GO:0007389 Not Cancer Driver No 20 0.139 27 2 0.074 0
IFT140 IFT140 Q96RY7 Intraflagellar transport protein 140 homolog chr16 GO:0007389 Not Cancer Driver No 176 0.12 161 27 0.168 10
IFT172 IFT172 Q9UG01 Intraflagellar transport protein 172 homolog chr2 GO:0007389 Not Cancer Driver No 219 0.125 96 10 0.104 8
IFT52_ENST00000373039 IFT52 Q9Y366 Intraflagellar transport protein 52 homolog chr20 GO:0007389 Not Cancer Driver No 60 0.137 56 7 0.125 1
IFT57 IFT57 Q9NWB7 Intraflagellar transport protein 57 homolog chr3 GO:0007389 Not Cancer Driver No 46 0.107 219 18 0.082 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0007389 Not Cancer Driver No 58 0.141 111 15 0.135 6
INTU INTU Q9ULD6 Protein inturned chr4 GO:0007389 Not Cancer Driver No 146 0.155 282 52 0.184 0
IRX1 IRX1 P78414 Iroquois-class homeodomain protein IRX-1 chr5 GO:0007389 Not Cancer Driver No 161 0.335 335 126 0.376 0
IRX2_ENST00000302057 IRX2 Q9BZI1 Iroquois-class homeodomain protein IRX-2 chr5 GO:0007389 Not Cancer Driver No 88 0.187 323 67 0.207 0
IRX3 IRX3 P78415 Iroquois-class homeodomain protein IRX-3 chr16 GO:0007389 Not Cancer Driver No 38 0.076 407 32 0.079 0
IRX4_ENST00000231357 IRX4 P78413 Iroquois-class homeodomain protein IRX-4 chr5 GO:0007389 Not Cancer Driver No 75 0.145 325 58 0.178 0
ISL1 ISL1 P61371 Insulin gene enhancer protein ISL-1 chr5 GO:0007389 Not Cancer Driver No 85 0.244 180 41 0.228 0
ITGAM_ENST00000287497 ITGAM P11215 Integrin alpha-M chr16 GO:0007389 Not Cancer Driver No 191 0.166 133 12 0.09 0
KAT2A KAT2A Q92830 Histone acetyltransferase KAT2A chr17 GO:0007389 Not Cancer Driver No 88 0.105 251 17 0.068 0
LDB1 LDB1 Q86U70 LIM domain-binding protein 1 chr10 GO:0007389 Compendium Yes 56 0.136 177 29 0.164 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0007389 Census Yes 64 0.16 370 57 0.154 0
LFNG LFNG Q8NES3 Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe chr7 GO:0007389 Not Cancer Driver No 37 0.098 65 1 0.015 1
LHX2 LHX2 P50458 LIM/homeobox protein Lhx2 chr9 GO:0007389 Not Cancer Driver No 60 0.148 203 28 0.138 0
LMX1B_ENST00000373474 LMX1B O60663 LIM homeobox transcription factor 1-beta chr9 GO:0007389 Not Cancer Driver No 63 0.157 196 30 0.153 32
LRP2 LRP2 P98164 Low-density lipoprotein receptor-related protein 2 chr2 GO:0007389 Not Cancer Driver No 998 0.214 209 40 0.191 1
LRP4 LRP4 O75096 Low-density lipoprotein receptor-related protein 4 chr11 GO:0007389 Not Cancer Driver No 233 0.122 265 28 0.106 11
MAFB MAFB Q9Y5Q3 Transcription factor MafB chr20 GO:0007389 Census Yes 35 0.108 301 34 0.113 10
MDFI MDFI Q99750 MyoD family inhibitor chr6 GO:0007389 Not Cancer Driver No 25 0.102 152 15 0.099 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0007389 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEGF8 MEGF8 Q7Z7M0 Multiple epidermal growth factor-like domains protein 8 chr19 GO:0007389 Not Cancer Driver No 363 0.128 476 59 0.124 3
MEIS1 MEIS1 O00470 Homeobox protein Meis1 chr2 GO:0007389 Not Cancer Driver No 89 0.228 267 62 0.232 0
MEIS2 MEIS2 O14770 Homeobox protein Meis2 chr15 GO:0007389 Not Cancer Driver No 94 0.197 358 76 0.212 0
MEIS3_ENST00000558555 MEIS3 Q99687 Homeobox protein Meis3 chr19 GO:0007389 Not Cancer Driver No 54 0.144 247 43 0.174 0
MEOX1 MEOX1 P50221 Homeobox protein MOX-1 chr17 GO:0007389 Not Cancer Driver No 46 0.181 236 44 0.186 0
MEOX2 MEOX2 P50222 Homeobox protein MOX-2 chr7 GO:0007389 Not Cancer Driver No 70 0.23 274 63 0.23 0
MESP1 MESP1 Q9BRJ9 Mesoderm posterior protein 1 chr15 GO:0007389 Not Cancer Driver No 8 0.03 247 7 0.028 0
MESP2 MESP2 Q0VG99 Mesoderm posterior protein 2 chr15 GO:0007389 Not Cancer Driver No 34 0.086 340 27 0.079 0
MFNG MFNG O00587 Beta-1,3-N-acetylglucosaminyltransferase manic fringe chr22 GO:0007389 Not Cancer Driver No 37 0.115 29 4 0.138 0
MIB1 MIB1 Q86YT6 E3 ubiquitin-protein ligase MIB1 chr18 GO:0007389 Not Cancer Driver No 122 0.121 282 34 0.121 1
MID1 MID1 O15344 E3 ubiquitin-protein ligase Midline-1 chrX GO:0007389 Not Cancer Driver No 86 0.129 86 16 0.186 4
MLLT3 MLLT3 P42568 Protein AF-9 chr9 GO:0007389 Census, Compendium Yes 69 0.121 414 58 0.14 0
MNS1 MNS1 Q8NEH6 Meiosis-specific nuclear structural protein 1 chr15 GO:0007389 Not Cancer Driver No 47 0.095 327 32 0.098 0
MSGN1 MSGN1 A6NI15 Mesogenin-1 chr2 GO:0007389 Not Cancer Driver No 54 0.28 161 44 0.273 0
MTF2 MTF2 Q9Y483 Metal-response element-binding transcription factor 2 chr1 GO:0007389 Not Cancer Driver No 70 0.118 225 28 0.124 0
MYF5 MYF5 P13349 Myogenic factor 5 chr12 GO:0007389 Not Cancer Driver No 103 0.404 122 60 0.492 1
MYF6 MYF6 P23409 Myogenic factor 6 chr12 GO:0007389 Not Cancer Driver No 89 0.368 118 44 0.373 0
NBL1_ENST00000602662 NBL1 P41271 Neuroblastoma suppressor of tumorigenicity 1 chr1 GO:0007389 Not Cancer Driver No 18 0.099 64 4 0.062 0
NEUROG1 NEUROG1 Q92886 Neurogenin-1 chr5 GO:0007389 Not Cancer Driver No 27 0.114 178 18 0.101 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0007389 Not Cancer Driver No 48 0.148 181 22 0.122 55
NKX3-1 NKX3-1 Q99801 Homeobox protein Nkx-3.1 chr8 GO:0007389 Not Cancer Driver No 35 0.15 171 16 0.094 0
NLE1 NLE1 Q9NVX2 Notchless protein homolog 1 chr17 GO:0007389 Not Cancer Driver No 60 0.124 21 3 0.143 0
NODAL NODAL Q96S42 Nodal homolog chr10 GO:0007389 Not Cancer Driver No 40 0.115 34 8 0.235 4
NOG NOG Q13253 Noggin chr17 GO:0007389 Not Cancer Driver No 22 0.095 86 9 0.105 20
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0007389 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0007389 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOTO NOTO A8MTQ0 Homeobox protein notochord chr2 GO:0007389 Not Cancer Driver No 15 0.06 116 6 0.052 0
NPHP3 NPHP3 Q7Z494 Nephrocystin-3 chr3 GO:0007389 Not Cancer Driver No 129 0.097 249 26 0.104 7
NR2F2 NR2F2 P24468 COUP transcription factor 2 chr15 GO:0007389 Not Cancer Driver No 66 0.159 101 1 0.01 5
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0007389 Not Cancer Driver No 9 0.079 11 1 0.091 0
NRG3_ENST00000404547 NRG3 P56975 Pro-neuregulin-3, membrane-bound isoform chr10 GO:0007389 Not Cancer Driver No 227 0.315 425 134 0.315 0
NTF4 NTF4 P34130 Neurotrophin-4 chr19 GO:0007389 Not Cancer Driver No 21 0.1 56 4 0.071 0
OOEP OOEP A6NGQ2 Oocyte-expressed protein homolog chr6 GO:0007389 Not Cancer Driver No 46 0.309 48 14 0.292 0
OSR1 OSR1 Q8TAX0 Protein odd-skipped-related 1 chr2 GO:0007389 Not Cancer Driver No 57 0.214 67 17 0.254 0
OVOL2 OVOL2 Q9BRP0 Transcription factor Ovo-like 2 chr20 GO:0007389 Not Cancer Driver No 29 0.105 139 8 0.058 0
PALB2 PALB2 Q86YC2 Partner and localizer of BRCA2 chr16 GO:0007389 Census Yes 124 0.105 769 77 0.1 1
PAX2_ENST00000428433 PAX2 Q02962 Paired box protein Pax-2 chr10 GO:0007389 Not Cancer Driver No 62 0.149 296 48 0.162 23
PAX6_ENST00000241001 PAX6 P26367 Paired box protein Pax-6 chr11 GO:0007389 Not Cancer Driver No 72 0.171 337 56 0.166 38
PAX8 PAX8 Q06710 Paired box protein Pax-8 chr2 GO:0007389 Census Yes 84 0.187 291 55 0.189 4
PBX1 PBX1 P40424 Pre-B-cell leukemia transcription factor 1 chr1 GO:0007389 Census Yes 82 0.191 290 57 0.197 0
PBX2 PBX2 P40425 Pre-B-cell leukemia transcription factor 2 chr6 GO:0007389 Not Cancer Driver No 57 0.133 297 43 0.145 0
PBX3 PBX3 P40426 Pre-B-cell leukemia transcription factor 3 chr9 GO:0007389 Not Cancer Driver No 59 0.136 290 40 0.138 0
PCDH8 PCDH8 O95206 Protocadherin-8 chr13 GO:0007389 Not Cancer Driver No 155 0.145 702 89 0.127 0
PCSK6 PCSK6 P29122 Proprotein convertase subtilisin/kexin type 6 chr15 GO:0007389 Not Cancer Driver No 138 0.142 207 45 0.217 0
PGAP1 PGAP1 Q75T13 GPI inositol-deacylase chr2 GO:0007389 Not Cancer Driver No 127 0.138 21 7 0.333 0
PIFO PIFO Q8TCI5 Protein pitchfork chr1 GO:0007389 Not Cancer Driver No 31 0.162 70 11 0.157 0
PITX2_ENST00000354925 PITX2 Q99697 Pituitary homeobox 2 chr4 GO:0007389 Not Cancer Driver No 74 0.233 185 43 0.232 13
PKD1L1 PKD1L1 Q8TDX9 Polycystic kidney disease protein 1-like 1 chr7 GO:0007389 Not Cancer Driver No 492 0.173 518 97 0.187 1
PKD2 PKD2 Q13563 Polycystin-2 chr4 GO:0007389 Not Cancer Driver No 113 0.117 375 35 0.093 10
PLXNA2 PLXNA2 O75051 Plexin-A2 chr1 GO:0007389 Not Cancer Driver No 312 0.165 142 25 0.176 0
POFUT1 POFUT1 Q9H488 GDP-fucose protein O-fucosyltransferase 1 chr20 GO:0007389 Not Cancer Driver No 56 0.144 17 2 0.118 0
POGLUT1 POGLUT1 Q8NBL1 Protein O-glucosyltransferase 1 chr3 GO:0007389 Not Cancer Driver No 57 0.145 0 0 0.0 3
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0007389 Not Cancer Driver No 538 0.13 421 61 0.145 2
PROP1 PROP1 O75360 Homeobox protein prophet of Pit-1 chr5 GO:0007389 Not Cancer Driver No 35 0.155 194 32 0.165 7
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0007389 Not Cancer Driver No 61 0.131 134 21 0.157 96
PTCH1 PTCH1 Q13635 Protein patched homolog 1 chr9 GO:0007389 Census, Compendium Yes 243 0.168 382 67 0.175 18
RAX RAX Q9Y2V3 Retinal homeobox protein Rx chr18 GO:0007389 Not Cancer Driver No 30 0.087 342 29 0.085 1
RBPJ_ENST00000361572 RBPJ Q06330 Recombining binding protein suppressor of hairless chr4 GO:0007389 Not Cancer Driver No 49 0.098 151 19 0.126 2
RELN RELN P78509 Reelin chr7 GO:0007389 Not Cancer Driver No 761 0.22 107 19 0.178 7
RFNG RFNG Q9Y644 Beta-1,3-N-acetylglucosaminyltransferase radical fringe chr17 GO:0007389 Not Cancer Driver No 22 0.066 92 5 0.054 0
RIPPLY1 RIPPLY1 Q0D2K3 Protein ripply1 chrX GO:0007389 Not Cancer Driver No 19 0.126 56 8 0.143 0
RIPPLY2 RIPPLY2 Q5TAB7 Protein ripply2 chr6 GO:0007389 Not Cancer Driver No 24 0.188 82 15 0.183 0
RIPPLY3 RIPPLY3 P57055 Protein ripply3 chr21 GO:0007389 Not Cancer Driver No 44 0.232 190 44 0.232 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0007389 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF2 RNF2 Q99496 E3 ubiquitin-protein ligase RING2 chr1 GO:0007389 Not Cancer Driver No 40 0.119 203 22 0.108 0
RNF220_ENST00000361799 RNF220 Q5VTB9 E3 ubiquitin-protein ligase RNF220 chr1 GO:0007389 Not Cancer Driver No 104 0.184 401 75 0.187 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0007389 Not Cancer Driver No 203 0.215 299 71 0.237 5
RPGRIP1L_ENST00000379925 RPGRIP1L Q68CZ1 Protein fantom chr16 GO:0007389 Not Cancer Driver No 177 0.135 586 94 0.16 8
SATB2 SATB2 Q9UPW6 DNA-binding protein SATB2 chr2 GO:0007389 Not Cancer Driver No 164 0.224 412 100 0.243 0
SEMA3C SEMA3C Q99985 Semaphorin-3C chr7 GO:0007389 Not Cancer Driver No 136 0.181 111 23 0.207 0
SETDB2 SETDB2 Q96T68 Histone-lysine N-methyltransferase SETDB2 chr13 GO:0007389 Not Cancer Driver No 70 0.097 253 26 0.103 0
SFRP1 SFRP1 Q8N474 Secreted frizzled-related protein 1 chr8 GO:0007389 Not Cancer Driver No 40 0.127 39 7 0.179 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0007389 Not Cancer Driver No 56 0.121 139 14 0.101 81
SHROOM3 SHROOM3 Q8TF72 Protein Shroom3 chr4 GO:0007389 Not Cancer Driver No 253 0.127 1756 220 0.125 0
SIM2 SIM2 Q14190 Single-minded homolog 2 chr21 GO:0007389 Not Cancer Driver No 62 0.093 262 12 0.046 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0007389 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX2 SIX2 Q9NPC8 Homeobox protein SIX2 chr2 GO:0007389 Census Yes 53 0.182 151 21 0.139 0
SIX3 SIX3 O95343 Homeobox protein SIX3 chr2 GO:0007389 Not Cancer Driver No 44 0.133 196 22 0.112 32
SKI SKI P12755 Ski oncogene chr1 GO:0007389 Census Yes 44 0.06 432 26 0.06 14
SMAD1 SMAD1 Q15797 Mothers against decapentaplegic homolog 1 chr4 GO:0007389 Not Cancer Driver No 54 0.116 161 22 0.137 0
SMAD2_ENST00000402690 SMAD2 Q15796 Mothers against decapentaplegic homolog 2 chr18 GO:0007389 Census, Compendium Yes 79 0.169 137 12 0.088 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0007389 Census, Compendium Yes 97 0.228 111 19 0.171 5
SMAD4_ENST00000398417 SMAD4 Q13485 Mothers against decapentaplegic homolog 4 chr18 GO:0007389 Census, Compendium Yes 198 0.359 195 17 0.087 8
SMAD5_ENST00000509297 SMAD5 Q99717 Mothers against decapentaplegic homolog 5 chr5 GO:0007389 Not Cancer Driver No 44 0.095 172 11 0.064 0
SMAD6 SMAD6 O43541 Mothers against decapentaplegic homolog 6 chr15 GO:0007389 Not Cancer Driver No 38 0.077 248 7 0.028 7
SMARCD3 SMARCD3 Q6STE5 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 chr7 GO:0007389 Not Cancer Driver No 64 0.133 213 18 0.085 0
SMO SMO Q99835 Smoothened homolog chr7 GO:0007389 Census, Compendium Yes 112 0.142 241 27 0.112 1
SNAI1 SNAI1 O95863 Zinc finger protein SNAI1 chr20 GO:0007389 Not Cancer Driver No 52 0.197 97 11 0.113 0
SOSTDC1 SOSTDC1 Q6X4U4 Sclerostin domain-containing protein 1 chr7 GO:0007389 Not Cancer Driver No 22 0.107 72 3 0.042 0
SOX17 SOX17 Q9H6I2 Transcription factor SOX-17 chr8 GO:0007389 Compendium Yes 81 0.196 378 59 0.156 2
SP8_ENST00000361443 SP8 Q8IXZ3 Transcription factor Sp8 chr7 GO:0007389 Not Cancer Driver No 37 0.076 263 21 0.08 0
STC1 STC1 P52823 Stanniocalcin-1 chr8 GO:0007389 Not Cancer Driver No 59 0.239 58 12 0.207 0
STIL_ENST00000360380 STIL Q15468 SCL-interrupting locus protein chr1 GO:0007389 Census, Compendium Yes 147 0.114 735 85 0.116 1
SYNGAP1_ENST00000646630 SYNGAP1 Q96PV0 Ras/Rap GTPase-activating protein SynGAP chr6 GO:0007389 Not Cancer Driver No 153 0.114 830 90 0.108 2
TBR1 TBR1 Q16650 T-box brain protein 1 chr2 GO:0007389 Not Cancer Driver No 88 0.129 413 56 0.136 5
TBX18 TBX18 O95935 T-box transcription factor TBX18 chr6 GO:0007389 Not Cancer Driver No 156 0.257 356 94 0.264 2
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0007389 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX20 TBX20 Q9UMR3 T-box transcription factor TBX20 chr7 GO:0007389 Not Cancer Driver No 117 0.262 201 54 0.269 2
TBX3 TBX3 O15119 T-box transcription factor TBX3 chr12 GO:0007389 Census, Compendium Yes 123 0.166 352 57 0.162 2
TBX5 TBX5 Q99593 T-box transcription factor TBX5 chr12 GO:0007389 Not Cancer Driver No 155 0.299 351 113 0.322 5
TBX6 TBX6 O95947 T-box transcription factor TBX6 chr16 GO:0007389 Not Cancer Driver No 44 0.101 253 25 0.099 0
TBXT TBXT O15178 T-box transcription factor T chr6 GO:0007389 Not Cancer Driver No 110 0.253 253 69 0.273 1
TCAP TCAP O15273 Telethonin chr17 GO:0007389 Not Cancer Driver No 16 0.096 94 10 0.106 3
TCF15 TCF15 Q12870 Transcription factor 15 chr20 GO:0007389 Not Cancer Driver No 19 0.095 134 4 0.03 0
TCTN1_ENST00000551590 TCTN1 Q2MV58 Tectonic-1 chr12 GO:0007389 Not Cancer Driver No 63 0.107 47 6 0.128 0
TDGF1 TDGF1 P13385 Teratocarcinoma-derived growth factor 1 chr3 GO:0007389 Not Cancer Driver No 39 0.207 25 2 0.08 0
TIFAB TIFAB Q6ZNK6 TRAF-interacting protein with FHA domain-containing protein B chr5 GO:0007389 Not Cancer Driver No 32 0.199 26 7 0.269 0
TLL1 TLL1 O43897 Tolloid-like protein 1 chr4 GO:0007389 Compendium Yes 333 0.329 138 57 0.413 3
TLL2 TLL2 Q9Y6L7 Tolloid-like protein 2 chr10 GO:0007389 Not Cancer Driver No 174 0.171 176 33 0.188 0
TMED2 TMED2 Q15363 Transmembrane emp24 domain-containing protein 2 chr12 GO:0007389 Not Cancer Driver No 24 0.119 25 4 0.16 0
TMEM107_ENST00000437139 TMEM107 Q6UX40 Transmembrane protein 107 chr17 GO:0007389 Not Cancer Driver No 12 0.086 0 0 0.0 1
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0007389 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0007389 Census, Compendium Yes 229 0.337 398 143 0.359 28
TRA2B TRA2B P62995 Transformer-2 protein homolog beta chr3 GO:0007389 Not Cancer Driver No 59 0.205 244 54 0.221 0
TTC21B TTC21B Q7Z4L5 Tetratricopeptide repeat protein 21B chr2 GO:0007389 Not Cancer Driver No 176 0.134 73 14 0.192 11
TTC8_ENST00000338104 TTC8 Q8TAM2 Tetratricopeptide repeat protein 8 chr14 GO:0007389 Not Cancer Driver No 74 0.137 98 12 0.122 0
UNCX UNCX A6NJT0 Homeobox protein unc-4 homolog chr7 GO:0007389 Not Cancer Driver No 28 0.053 410 17 0.041 0
VAX2 VAX2 Q9UIW0 Ventral anterior homeobox 2 chr2 GO:0007389 Not Cancer Driver No 34 0.117 210 22 0.105 0
WDR77 WDR77 Q9BQA1 Methylosome protein 50 chr1 GO:0007389 Not Cancer Driver No 30 0.088 41 2 0.049 0
WLS_ENST00000262348 WLS Q5T9L3 Protein wntless homolog chr1 GO:0007389 Not Cancer Driver No 71 0.131 14 3 0.214 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0007389 Not Cancer Driver No 29 0.078 25 0 0.0 8
WNT11 WNT11 O96014 Protein Wnt-11 chr11 GO:0007389 Not Cancer Driver No 55 0.155 59 4 0.068 0
WNT2B WNT2B Q93097 Protein Wnt-2b chr1 GO:0007389 Not Cancer Driver No 72 0.184 27 3 0.111 0
WNT3 WNT3 P56703 Proto-oncogene Wnt-3 chr17 GO:0007389 Not Cancer Driver No 56 0.158 34 7 0.206 0
WNT3A WNT3A P56704 Protein Wnt-3a chr1 GO:0007389 Not Cancer Driver No 77 0.219 37 5 0.135 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0007389 Not Cancer Driver No 66 0.174 0 0 0.0 2
WNT6 WNT6 Q9Y6F9 Protein Wnt-6 chr2 GO:0007389 Not Cancer Driver No 30 0.082 84 9 0.107 0
WNT7A WNT7A O00755 Protein Wnt-7a chr3 GO:0007389 Not Cancer Driver No 93 0.266 18 9 0.5 4
WNT7B WNT7B P56706 Protein Wnt-7b chr22 GO:0007389 Not Cancer Driver No 55 0.158 11 1 0.091 0
WNT8A_ENST00000398754 WNT8A Q9H1J5 Protein Wnt-8a chr5 GO:0007389 Not Cancer Driver No 50 0.142 3 0 0.0 0
WNT8B WNT8B Q93098 Protein Wnt-8b chr10 GO:0007389 Not Cancer Driver No 50 0.142 27 5 0.185 0
XRCC2 XRCC2 O43543 DNA repair protein XRCC2 chr7 GO:0007389 Not Cancer Driver No 36 0.129 9 1 0.111 2
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0007389 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZEB1_ENST00000320985 ZEB1 P37275 Zinc finger E-box-binding homeobox 1 chr10 GO:0007389 Census, Compendium Yes 246 0.219 831 200 0.241 8
ZIC1 ZIC1 Q15915 Zinc finger protein ZIC 1 chr3 GO:0007389 Not Cancer Driver No 187 0.418 246 113 0.459 1
ZIC3 ZIC3 O60481 Zinc finger protein ZIC 3 chrX GO:0007389 Not Cancer Driver No 100 0.214 327 66 0.202 10