Filter in search result
Please select a valid state.

Total number of protein in "GO:0007268" GO term:  269

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0007268 Not Cancer Driver No 61 0.148 93 11 0.118 0
AKAP5_ENST00000320636 AKAP5 P24588 A-kinase anchor protein 5 chr14 GO:0007268 Not Cancer Driver No 37 0.087 405 34 0.084 0
AKAP9 AKAP9 Q99996 A-kinase anchor protein 9 chr7 GO:0007268 Census Yes 474 0.121 2281 268 0.117 1
AMPH AMPH P49418 Amphiphysin chr7 GO:0007268 Not Cancer Driver No 202 0.291 473 131 0.277 0
APBA1 APBA1 Q02410 Amyloid-beta A4 precursor protein-binding family A member 1 chr9 GO:0007268 Not Cancer Driver No 149 0.178 556 103 0.185 0
APBA2_ENST00000561069 APBA2 Q99767 Amyloid-beta A4 precursor protein-binding family A member 2 chr15 GO:0007268 Not Cancer Driver No 184 0.246 429 117 0.273 0
APBA3 APBA3 O96018 Amyloid-beta A4 precursor protein-binding family A member 3 chr19 GO:0007268 Not Cancer Driver No 55 0.096 306 43 0.141 0
ASIC2_ENST00000359872 ASIC2 Q16515 Acid-sensing ion channel 2 chr17 GO:0007268 Not Cancer Driver No 101 0.197 49 1 0.02 0
ATXN3 ATXN3 P54252 Ataxin-3 chr14 GO:0007268 Not Cancer Driver No 46 0.127 181 24 0.133 0
BSN BSN Q9UPA5 Protein bassoon chr3 GO:0007268 Not Cancer Driver No 531 0.135 3702 510 0.138 0
CACNA1A_ENST00000360228 CACNA1A O00555 Voltage-dependent P/Q-type calcium channel subunit alpha-1A chr19 GO:0007268 Not Cancer Driver No 436 0.174 1144 132 0.115 46
CACNA1B CACNA1B Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B chr9 GO:0007268 Not Cancer Driver No 416 0.178 917 115 0.125 0
CACNA1E_ENST00000621551 CACNA1E Q15878 Voltage-dependent R-type calcium channel subunit alpha-1E chr1 GO:0007268 Not Cancer Driver No 778 0.336 917 339 0.37 14
CACNA1G CACNA1G O43497 Voltage-dependent T-type calcium channel subunit alpha-1G chr17 GO:0007268 Not Cancer Driver No 367 0.154 1022 149 0.146 3
CACNB1 CACNB1 Q02641 Voltage-dependent L-type calcium channel subunit beta-1 chr17 GO:0007268 Not Cancer Driver No 75 0.125 396 47 0.119 0
CACNB2 CACNB2 Q08289 Voltage-dependent L-type calcium channel subunit beta-2 chr10 GO:0007268 Not Cancer Driver No 155 0.235 478 106 0.222 0
CACNB3 CACNB3 P54284 Voltage-dependent L-type calcium channel subunit beta-3 chr12 GO:0007268 Not Cancer Driver No 58 0.12 258 30 0.116 0
CACNB4 CACNB4 O00305 Voltage-dependent L-type calcium channel subunit beta-4 chr2 GO:0007268 Not Cancer Driver No 82 0.158 295 49 0.166 1
CARTPT CARTPT Q16568 Cocaine- and amphetamine-regulated transcript protein chr5 GO:0007268 Not Cancer Driver No 18 0.155 0 0 0.0 0
CBLN1 CBLN1 P23435 Cerebellin-1 chr16 GO:0007268 Not Cancer Driver No 46 0.238 14 2 0.143 0
CBLN2 CBLN2 Q8IUK8 Cerebellin-2 chr18 GO:0007268 Not Cancer Driver No 78 0.348 35 8 0.229 0
CDK5 CDK5 Q00535 Cyclin-dependent kinase 5 chr7 GO:0007268 Not Cancer Driver No 48 0.164 5 1 0.2 0
CEL CEL P19835 Bile salt-activated lipase chr9 GO:0007268 Not Cancer Driver No 101 0.134 280 40 0.143 0
CEP89 CEP89 Q96ST8 Centrosomal protein of 89 kDa chr19 GO:0007268 Census Yes 96 0.123 540 72 0.133 0
CHRFAM7A CHRFAM7A Q494W8 CHRNA7-FAM7A fusion protein chr15 GO:0007268 Not Cancer Driver No 40 0.097 18 0 0.0 0
CHRM1 CHRM1 P11229 Muscarinic acetylcholine receptor M1 chr11 GO:0007268 Not Cancer Driver No 63 0.137 131 24 0.183 0
CHRM2_ENST00000320658 CHRM2 P08172 Muscarinic acetylcholine receptor M2 chr7 GO:0007268 Not Cancer Driver No 218 0.468 169 93 0.55 0
CHRM3_ENST00000615928 CHRM3 P20309 Muscarinic acetylcholine receptor M3 chr1 GO:0007268 Not Cancer Driver No 182 0.308 136 42 0.309 0
CHRM4 CHRM4 P08173 Muscarinic acetylcholine receptor M4 chr11 GO:0007268 Not Cancer Driver No 75 0.157 143 27 0.189 0
CHRM5 CHRM5 P08912 Muscarinic acetylcholine receptor M5 chr15 GO:0007268 Not Cancer Driver No 74 0.139 155 20 0.129 0
CHRNA10 CHRNA10 Q9GZZ6 Neuronal acetylcholine receptor subunit alpha-10 chr11 GO:0007268 Not Cancer Driver No 65 0.144 34 5 0.147 0
CHRNA1_ENST00000348749 CHRNA1 P02708 Acetylcholine receptor subunit alpha chr2 GO:0007268 Not Cancer Driver No 86 0.188 9 1 0.111 12
CHRNA2 CHRNA2 Q15822 Neuronal acetylcholine receptor subunit alpha-2 chr8 GO:0007268 Not Cancer Driver No 85 0.161 33 5 0.152 1
CHRNA3 CHRNA3 P32297 Neuronal acetylcholine receptor subunit alpha-3 chr15 GO:0007268 Not Cancer Driver No 86 0.17 11 1 0.091 0
CHRNA4 CHRNA4 P43681 Neuronal acetylcholine receptor subunit alpha-4 chr20 GO:0007268 Not Cancer Driver No 144 0.23 186 33 0.177 2
CHRNA5 CHRNA5 P30532 Neuronal acetylcholine receptor subunit alpha-5 chr15 GO:0007268 Not Cancer Driver No 63 0.135 24 3 0.125 0
CHRNA6 CHRNA6 Q15825 Neuronal acetylcholine receptor subunit alpha-6 chr8 GO:0007268 Not Cancer Driver No 101 0.204 33 6 0.182 0
CHRNA7_ENST00000306901 CHRNA7 P36544 Neuronal acetylcholine receptor subunit alpha-7 chr15 GO:0007268 Not Cancer Driver No 71 0.141 18 4 0.222 0
CHRNA9 CHRNA9 Q9UGM1 Neuronal acetylcholine receptor subunit alpha-9 chr4 GO:0007268 Not Cancer Driver No 76 0.159 23 6 0.261 0
CHRNB1 CHRNB1 P11230 Acetylcholine receptor subunit beta chr17 GO:0007268 Not Cancer Driver No 62 0.124 45 9 0.2 3
CHRNB2 CHRNB2 P17787 Neuronal acetylcholine receptor subunit beta-2 chr1 GO:0007268 Not Cancer Driver No 92 0.183 23 2 0.087 2
CHRNB3 CHRNB3 Q05901 Neuronal acetylcholine receptor subunit beta-3 chr8 GO:0007268 Not Cancer Driver No 125 0.273 4 1 0.25 0
CHRNB4 CHRNB4 P30926 Neuronal acetylcholine receptor subunit beta-4 chr15 GO:0007268 Not Cancer Driver No 98 0.197 30 6 0.2 0
CHRND CHRND Q07001 Acetylcholine receptor subunit delta chr2 GO:0007268 Not Cancer Driver No 110 0.213 71 19 0.268 7
CHRNE CHRNE Q04844 Acetylcholine receptor subunit epsilon chr17 GO:0007268 Not Cancer Driver No 52 0.105 37 3 0.081 13
CHRNG CHRNG P07510 Acetylcholine receptor subunit gamma chr2 GO:0007268 Not Cancer Driver No 78 0.151 8 1 0.125 4
CLCN3_ENST00000513761 CLCN3 P51790 H(+)/Cl(-) exchange transporter 3 chr4 GO:0007268 Not Cancer Driver No 105 0.128 88 7 0.08 0
CLSTN3 CLSTN3 Q9BQT9 Calsyntenin-3 chr12 GO:0007268 Not Cancer Driver No 140 0.146 211 27 0.128 0
CNP CNP P09543 2',3'-cyclic-nucleotide 3'-phosphodiesterase chr17 GO:0007268 Not Cancer Driver No 36 0.086 71 2 0.028 0
CORT CORT O00230 Cortistatin chr1 GO:0007268 Not Cancer Driver No 11 0.105 46 4 0.087 0
CPLX1 CPLX1 O14810 Complexin-1 chr4 GO:0007268 Not Cancer Driver No 19 0.142 134 19 0.142 0
CRH CRH P06850 Corticoliberin chr8 GO:0007268 Not Cancer Driver No 10 0.051 131 9 0.069 0
CRHBP CRHBP P24387 Corticotropin-releasing factor-binding protein chr5 GO:0007268 Not Cancer Driver No 61 0.189 0 0 0.0 0
CTNNB1_ENST00000643977 CTNNB1 P35222 Catenin beta-1 chr3 GO:0007268 Census, Compendium Yes 415 0.531 288 301 1.045 14
DBH DBH P09172 Dopamine beta-hydroxylase chr9 GO:0007268 Not Cancer Driver No 125 0.203 71 17 0.239 3
DLG1_ENST00000419354 DLG1 Q12959 Disks large homolog 1 chr3 GO:0007268 Not Cancer Driver No 120 0.133 460 67 0.146 0
DLG2_ENST00000398309 DLG2 Q15700 Disks large homolog 2 chr11 GO:0007268 Not Cancer Driver No 224 0.257 303 107 0.353 0
DLG4_ENST00000399506 DLG4 P78352 Disks large homolog 4 chr17 GO:0007268 Not Cancer Driver No 116 0.16 232 55 0.237 0
DLGAP1 DLGAP1 O14490 Disks large-associated protein 1 chr18 GO:0007268 Not Cancer Driver No 178 0.182 789 149 0.189 0
DLGAP2_ENST00000421627 DLGAP2 Q9P1A6 Disks large-associated protein 2 chr8 GO:0007268 Not Cancer Driver No 239 0.227 879 207 0.235 0
DOC2A_ENST00000564979 DOC2A Q14183 Double C2-like domain-containing protein alpha chr16 GO:0007268 Not Cancer Driver No 59 0.147 111 16 0.144 0
DRD1 DRD1 P21728 D(1A) dopamine receptor chr5 GO:0007268 Not Cancer Driver No 73 0.164 30 4 0.133 0
DRD2_ENST00000542968 DRD2 P14416 D(2) dopamine receptor chr11 GO:0007268 Not Cancer Driver No 127 0.287 124 45 0.363 0
DRD3_ENST00000460779 DRD3 P35462 D(3) dopamine receptor chr3 GO:0007268 Not Cancer Driver No 88 0.22 45 17 0.378 0
DRD4 DRD4 P21917 D(4) dopamine receptor chr11 GO:0007268 Not Cancer Driver No 26 0.062 109 0 0.0 0
DRD5 DRD5 P21918 D(1B) dopamine receptor chr4 GO:0007268 Not Cancer Driver No 172 0.361 29 18 0.621 0
DTNA_ENST00000444659 DTNA Q9Y4J8 Dystrobrevin alpha chr18 GO:0007268 Not Cancer Driver No 162 0.218 412 86 0.209 0
EXOC4 EXOC4 Q96A65 Exocyst complex component 4 chr7 GO:0007268 Not Cancer Driver No 164 0.168 133 33 0.248 0
EZH2_ENST00000460911 EZH2 Q15910 Histone-lysine N-methyltransferase EZH2 chr7 GO:0007268 Census, Compendium Yes 120 0.161 284 44 0.155 11
FGF12 FGF12 P61328 Fibroblast growth factor 12 chr3 GO:0007268 Not Cancer Driver No 74 0.305 102 30 0.294 1
GABARAP GABARAP O95166 Gamma-aminobutyric acid receptor-associated protein chr17 GO:0007268 Not Cancer Driver No 9 0.077 11 0 0.0 0
GABBR2 GABBR2 O75899 Gamma-aminobutyric acid type B receptor subunit 2 chr9 GO:0007268 Not Cancer Driver No 169 0.18 220 29 0.132 4
GABRA1_ENST00000638112 GABRA1 P14867 Gamma-aminobutyric acid receptor subunit alpha-1 chr5 GO:0007268 Not Cancer Driver No 175 0.384 58 31 0.534 6
GABRA2_ENST00000356504 GABRA2 P47869 Gamma-aminobutyric acid receptor subunit alpha-2 chr4 GO:0007268 Not Cancer Driver No 194 0.43 26 13 0.5 5
GABRA3_ENST00000535043 GABRA3 P34903 Gamma-aminobutyric acid receptor subunit alpha-3 chrX GO:0007268 Not Cancer Driver No 136 0.276 47 10 0.213 0
GABRA4 GABRA4 P48169 Gamma-aminobutyric acid receptor subunit alpha-4 chr4 GO:0007268 Not Cancer Driver No 191 0.345 179 82 0.458 0
GABRA5_ENST00000355395 GABRA5 P31644 Gamma-aminobutyric acid receptor subunit alpha-5 chr15 GO:0007268 Not Cancer Driver No 146 0.316 55 14 0.255 3
GABRA6 GABRA6 Q16445 Gamma-aminobutyric acid receptor subunit alpha-6 chr5 GO:0007268 Not Cancer Driver No 186 0.411 7 2 0.286 0
GABRB1 GABRB1 P18505 Gamma-aminobutyric acid receptor subunit beta-1 chr4 GO:0007268 Not Cancer Driver No 133 0.281 43 14 0.326 2
GABRB2_ENST00000393959 GABRB2 P47870 Gamma-aminobutyric acid receptor subunit beta-2 chr5 GO:0007268 Not Cancer Driver No 165 0.322 27 10 0.37 1
GABRB3 GABRB3 P28472 Gamma-aminobutyric acid receptor subunit beta-3 chr15 GO:0007268 Not Cancer Driver No 178 0.376 56 22 0.393 9
GABRD GABRD O14764 Gamma-aminobutyric acid receptor subunit delta chr1 GO:0007268 Not Cancer Driver No 71 0.157 19 5 0.263 1
GABRE GABRE P78334 Gamma-aminobutyric acid receptor subunit epsilon chrX GO:0007268 Not Cancer Driver No 133 0.263 73 19 0.26 0
GABRG1 GABRG1 Q8N1C3 Gamma-aminobutyric acid receptor subunit gamma-1 chr4 GO:0007268 Not Cancer Driver No 216 0.465 7 3 0.429 0
GABRG2_ENST00000639213 GABRG2 P18507 Gamma-aminobutyric acid receptor subunit gamma-2 chr5 GO:0007268 Not Cancer Driver No 188 0.403 19 13 0.684 11
GABRG3 GABRG3 Q99928 Gamma-aminobutyric acid receptor subunit gamma-3 chr15 GO:0007268 Not Cancer Driver No 137 0.293 12 5 0.417 0
GABRP_ENST00000265294 GABRP O00591 Gamma-aminobutyric acid receptor subunit pi chr5 GO:0007268 Not Cancer Driver No 81 0.184 0 0 0.0 0
GABRQ GABRQ Q9UN88 Gamma-aminobutyric acid receptor subunit theta chrX GO:0007268 Not Cancer Driver No 158 0.25 175 58 0.331 0
GABRR1 GABRR1 P24046 Gamma-aminobutyric acid receptor subunit rho-1 chr6 GO:0007268 Not Cancer Driver No 93 0.194 99 26 0.263 0
GABRR2 GABRR2 P28476 Gamma-aminobutyric acid receptor subunit rho-2 chr6 GO:0007268 Not Cancer Driver No 64 0.138 8 0 0.0 0
GABRR3 GABRR3 A8MPY1 Gamma-aminobutyric acid receptor subunit rho-3 chr3 GO:0007268 Not Cancer Driver No 76 0.163 30 7 0.233 0
GAD1 GAD1 Q99259 Glutamate decarboxylase 1 chr2 GO:0007268 Not Cancer Driver No 113 0.19 55 5 0.091 1
GAD2_ENST00000259271 GAD2 Q05329 Glutamate decarboxylase 2 chr10 GO:0007268 Not Cancer Driver No 148 0.253 37 7 0.189 0
GALR3 GALR3 O60755 Galanin receptor type 3 chr22 GO:0007268 Not Cancer Driver No 15 0.041 53 0 0.0 0
GIPC1 GIPC1 O14908 PDZ domain-containing protein GIPC1 chr19 GO:0007268 Not Cancer Driver No 47 0.141 138 17 0.123 0
GJC1_ENST00000590758 GJC1 P36383 Gap junction gamma-1 protein chr17 GO:0007268 Not Cancer Driver No 63 0.159 150 30 0.2 0
GJD2 GJD2 Q9UKL4 Gap junction delta-2 protein chr15 GO:0007268 Not Cancer Driver No 86 0.268 58 17 0.293 0
GLRA1 GLRA1 P23415 Glycine receptor subunit alpha-1 chr5 GO:0007268 Not Cancer Driver No 92 0.201 37 2 0.054 18
GLRA2 GLRA2 P23416 Glycine receptor subunit alpha-2 chrX GO:0007268 Not Cancer Driver No 106 0.235 58 14 0.241 0
GLRA3 GLRA3 O75311 Glycine receptor subunit alpha-3 chr4 GO:0007268 Not Cancer Driver No 132 0.284 32 11 0.344 0
GLRB GLRB P48167 Glycine receptor subunit beta chr4 GO:0007268 Not Cancer Driver No 112 0.225 66 12 0.182 4
GLS GLS O94925 Glutaminase kidney isoform, mitochondrial chr2 GO:0007268 Not Cancer Driver No 71 0.106 187 9 0.048 3
GPR176 GPR176 Q14439 G-protein coupled receptor 176 chr15 GO:0007268 Not Cancer Driver No 63 0.122 124 17 0.137 0
GRIA1_ENST00000285900 GRIA1 P42261 Glutamate receptor 1 chr5 GO:0007268 Not Cancer Driver No 303 0.334 104 45 0.433 0
GRIA2_ENST00000264426 GRIA2 P42262 Glutamate receptor 2 chr4 GO:0007268 Not Cancer Driver No 290 0.328 50 16 0.32 14
GRIK1_ENST00000399907 GRIK1 P39086 Glutamate receptor ionotropic, kainate 1 chr21 GO:0007268 Not Cancer Driver No 196 0.214 50 5 0.1 0
GRIK2 GRIK2 Q13002 Glutamate receptor ionotropic, kainate 2 chr6 GO:0007268 Not Cancer Driver No 284 0.313 57 19 0.333 0
GRIK4_ENST00000438375 GRIK4 Q16099 Glutamate receptor ionotropic, kainate 4 chr11 GO:0007268 Not Cancer Driver No 179 0.187 74 8 0.108 0
GRIN1_ENST00000371561 GRIN1 Q05586 Glutamate receptor ionotropic, NMDA 1 chr9 GO:0007268 Not Cancer Driver No 88 0.094 190 15 0.079 13
GRIN2A_ENST00000330684 GRIN2A Q12879 Glutamate receptor ionotropic, NMDA 2A chr16 GO:0007268 Census, Compendium Yes 528 0.361 506 207 0.409 31
GRIN2B GRIN2B Q13224 Glutamate receptor ionotropic, NMDA 2B chr12 GO:0007268 Not Cancer Driver No 413 0.278 426 147 0.345 11
GRIN2C GRIN2C Q14957 Glutamate receptor ionotropic, NMDA 2C chr17 GO:0007268 Not Cancer Driver No 111 0.09 276 6 0.022 0
GRIN2D GRIN2D O15399 Glutamate receptor ionotropic, NMDA 2D chr19 GO:0007268 Not Cancer Driver No 125 0.094 467 15 0.032 1
GRM1_ENST00000282753 GRM1 Q13255 Metabotropic glutamate receptor 1 chr6 GO:0007268 Not Cancer Driver No 346 0.29 339 91 0.268 3
GRM2 GRM2 Q14416 Metabotropic glutamate receptor 2 chr3 GO:0007268 Not Cancer Driver No 143 0.164 24 3 0.125 0
GRM3 GRM3 Q14832 Metabotropic glutamate receptor 3 chr7 GO:0007268 Census Yes 323 0.367 8 3 0.375 0
GRM4 GRM4 Q14833 Metabotropic glutamate receptor 4 chr6 GO:0007268 Not Cancer Driver No 187 0.205 74 22 0.297 0
GRM5 GRM5 P41594 Metabotropic glutamate receptor 5 chr11 GO:0007268 Not Cancer Driver No 312 0.257 323 51 0.158 0
GRM6_ENST00000517717 GRM6 O15303 Metabotropic glutamate receptor 6 chr5 GO:0007268 Not Cancer Driver No 200 0.228 113 23 0.204 6
GRM7 GRM7 Q14831 Metabotropic glutamate receptor 7 chr3 GO:0007268 Not Cancer Driver No 316 0.345 91 31 0.341 1
HAP1_ENST00000310778 HAP1 P54257 Huntingtin-associated protein 1 chr17 GO:0007268 Not Cancer Driver No 97 0.145 454 60 0.132 0
HCRT HCRT O43612 Orexin chr17 GO:0007268 Not Cancer Driver No 3 0.023 45 0 0.0 1
HCRTR1 HCRTR1 O43613 Orexin/Hypocretin receptor type 1 chr1 GO:0007268 Not Cancer Driver No 52 0.122 28 0 0.0 0
HCRTR2 HCRTR2 O43614 Orexin receptor type 2 chr6 GO:0007268 Not Cancer Driver No 154 0.347 38 13 0.342 0
HOMER1 HOMER1 Q86YM7 Homer protein homolog 1 chr5 GO:0007268 Not Cancer Driver No 46 0.13 243 32 0.132 0
HRH1_ENST00000438284 HRH1 P35367 Histamine H1 receptor chr3 GO:0007268 Not Cancer Driver No 96 0.197 122 26 0.213 0
HRH2_ENST00000231683 HRH2 P25021 Histamine H2 receptor chr5 GO:0007268 Not Cancer Driver No 84 0.234 44 6 0.136 0
HRH3 HRH3 Q9Y5N1 Histamine H3 receptor chr20 GO:0007268 Not Cancer Driver No 65 0.146 93 10 0.108 0
HRH4 HRH4 Q9H3N8 Histamine H4 receptor chr18 GO:0007268 Not Cancer Driver No 72 0.185 1 1 1.0 0
HTR1A HTR1A P08908 5-hydroxytryptamine receptor 1A chr5 GO:0007268 Not Cancer Driver No 170 0.403 100 49 0.49 0
HTR1B HTR1B P28222 5-hydroxytryptamine receptor 1B chr6 GO:0007268 Not Cancer Driver No 91 0.233 33 15 0.455 0
HTR1D HTR1D P28221 5-hydroxytryptamine receptor 1D chr1 GO:0007268 Not Cancer Driver No 54 0.143 24 1 0.042 0
HTR1E HTR1E P28566 5-hydroxytryptamine receptor 1E chr6 GO:0007268 Not Cancer Driver No 133 0.364 18 5 0.278 0
HTR1F HTR1F P30939 5-hydroxytryptamine receptor 1F chr3 GO:0007268 Not Cancer Driver No 83 0.227 3 0 0.0 0
HTR2A HTR2A P28223 5-hydroxytryptamine receptor 2A chr13 GO:0007268 Not Cancer Driver No 105 0.223 44 8 0.182 0
HTR2B HTR2B P41595 5-hydroxytryptamine receptor 2B chr2 GO:0007268 Not Cancer Driver No 41 0.085 23 2 0.087 0
HTR2C HTR2C P28335 5-hydroxytryptamine receptor 2C chrX GO:0007268 Not Cancer Driver No 140 0.306 40 11 0.275 0
HTR3A_ENST00000504030 HTR3A P46098 5-hydroxytryptamine receptor 3A chr11 GO:0007268 Not Cancer Driver No 127 0.266 45 13 0.289 0
HTR3B HTR3B O95264 5-hydroxytryptamine receptor 3B chr11 GO:0007268 Not Cancer Driver No 91 0.206 8 0 0.0 0
HTR3C HTR3C Q8WXA8 5-hydroxytryptamine receptor 3C chr3 GO:0007268 Not Cancer Driver No 82 0.183 35 7 0.2 0
HTR3D HTR3D Q70Z44 5-hydroxytryptamine receptor 3D chr3 GO:0007268 Not Cancer Driver No 61 0.134 59 16 0.271 0
HTR3E_ENST00000415389 HTR3E A5X5Y0 5-hydroxytryptamine receptor 3E chr3 GO:0007268 Not Cancer Driver No 87 0.191 56 18 0.321 0
HTR4_ENST00000377888 HTR4 Q13639 5-hydroxytryptamine receptor 4 chr5 GO:0007268 Not Cancer Driver No 77 0.198 26 9 0.346 0
HTR5A HTR5A P47898 5-hydroxytryptamine receptor 5A chr7 GO:0007268 Not Cancer Driver No 174 0.487 6 1 0.167 0
HTR6 HTR6 P50406 5-hydroxytryptamine receptor 6 chr1 GO:0007268 Not Cancer Driver No 78 0.177 136 27 0.199 0
HTR7 HTR7 P34969 5-hydroxytryptamine receptor 7 chr10 GO:0007268 Not Cancer Driver No 102 0.213 24 1 0.042 0
KCNA1 KCNA1 Q09470 Potassium voltage-gated channel subfamily A member 1 chr12 GO:0007268 Not Cancer Driver No 176 0.356 69 34 0.493 17
KCNC4 KCNC4 Q03721 Potassium voltage-gated channel subfamily C member 4 chr1 GO:0007268 Not Cancer Driver No 105 0.165 244 38 0.156 0
KCND2 KCND2 Q9NZV8 Potassium voltage-gated channel subfamily D member 2 chr7 GO:0007268 Not Cancer Driver No 220 0.349 195 62 0.318 0
KCNIP2_ENST00000356640 KCNIP2 Q9NS61 Kv channel-interacting protein 2 chr10 GO:0007268 Not Cancer Driver No 34 0.126 89 16 0.18 0
KCNK3 KCNK3 O14649 Potassium channel subfamily K member 3 chr2 GO:0007268 Not Cancer Driver No 54 0.137 60 7 0.117 6
KCNMB1 KCNMB1 Q16558 Calcium-activated potassium channel subunit beta-1 chr5 GO:0007268 Not Cancer Driver No 49 0.257 0 0 0.0 0
KCNMB4 KCNMB4 Q86W47 Calcium-activated potassium channel subunit beta-4 chr12 GO:0007268 Not Cancer Driver No 41 0.195 0 0 0.0 0
KCNN1 KCNN1 Q92952 Small conductance calcium-activated potassium channel protein 1 chr19 GO:0007268 Not Cancer Driver No 83 0.153 192 19 0.099 0
KCNQ2 KCNQ2 O43526 Potassium voltage-gated channel subfamily KQT member 2 chr20 GO:0007268 Not Cancer Driver No 171 0.196 393 81 0.206 37
KCNQ3 KCNQ3 O43525 Potassium voltage-gated channel subfamily KQT member 3 chr8 GO:0007268 Not Cancer Driver No 249 0.286 411 109 0.265 3
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 GO:0007268 Not Cancer Driver No 253 0.139 633 106 0.167 1
KIF5A KIF5A Q12840 Kinesin heavy chain isoform 5A chr12 GO:0007268 Not Cancer Driver No 194 0.188 569 103 0.181 14
LPAR3_ENST00000370611 LPAR3 Q9UBY5 Lysophosphatidic acid receptor 3 chr1 GO:0007268 Not Cancer Driver No 65 0.184 9 0 0.0 0
LRP6 LRP6 O75581 Low-density lipoprotein receptor-related protein 6 chr12 GO:0007268 Not Cancer Driver No 206 0.128 255 30 0.118 5
LRP8 LRP8 Q14114 Low-density lipoprotein receptor-related protein 8 chr1 GO:0007268 Not Cancer Driver No 94 0.098 190 24 0.126 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0007268 Census, Compendium Yes 62 0.172 2 0 0.0 7
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0007268 Not Cancer Driver No 52 0.171 304 52 0.171 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0007268 Not Cancer Driver No 113 0.085 740 56 0.076 0
MPZ MPZ P25189 Myelin protein P0 chr1 GO:0007268 Not Cancer Driver No 26 0.105 49 4 0.082 90
MTNR1B MTNR1B P49286 Melatonin receptor type 1B chr11 GO:0007268 Not Cancer Driver No 104 0.287 8 1 0.125 0
MYCBPAP_ENST00000436259 MYCBPAP Q8TBZ2 MYCBP-associated protein chr17 GO:0007268 Not Cancer Driver No 144 0.152 534 81 0.152 0
NLGN1_ENST00000361589 NLGN1 Q8N2Q7 Neuroligin-1 chr3 GO:0007268 Not Cancer Driver No 214 0.248 248 61 0.246 4
NLGN2 NLGN2 Q8NFZ4 Neuroligin-2 chr17 GO:0007268 Not Cancer Driver No 91 0.109 300 19 0.063 0
NLGN3 NLGN3 Q9NZ94 Neuroligin-3 chrX GO:0007268 Not Cancer Driver No 158 0.186 257 54 0.21 2
NLGN4X_ENST00000381093 NLGN4X Q8N0W4 Neuroligin-4, X-linked chrX GO:0007268 Not Cancer Driver No 279 0.342 211 81 0.384 0
NLGN4Y NLGN4Y Q8NFZ3 Neuroligin-4, Y-linked chrY GO:0007268 Not Cancer Driver No 94 0.115 206 26 0.126 0
NPBWR1 NPBWR1 P48145 Neuropeptides B/W receptor type 1 chr8 GO:0007268 Not Cancer Driver No 72 0.22 3 0 0.0 0
NPFF NPFF O15130 Pro-FMRFamide-related neuropeptide FF chr12 GO:0007268 Not Cancer Driver No 16 0.142 64 7 0.109 0
NPTX1 NPTX1 Q15818 Neuronal pentraxin-1 chr17 GO:0007268 Not Cancer Driver No 63 0.146 185 24 0.13 0
NPTX2 NPTX2 P47972 Neuronal pentraxin-2 chr7 GO:0007268 Not Cancer Driver No 78 0.181 165 10 0.061 0
NPY5R_ENST00000506953 NPY5R Q15761 Neuropeptide Y receptor type 5 chr4 GO:0007268 Not Cancer Driver No 144 0.324 44 16 0.364 0
NPY_ENST00000405982 NPY P01303 Pro-neuropeptide Y chr7 GO:0007268 Not Cancer Driver No 29 0.299 43 19 0.442 0
NRXN1_ENST00000406316 NRXN1 Q9ULB1 Neurexin-1 chr2 GO:0007268 Not Cancer Driver No 593 0.401 301 110 0.365 0
NRXN2_ENST00000377551 NRXN2 Q9P2S2 Neurexin-2 chr11 GO:0007268 Not Cancer Driver No 278 0.162 547 80 0.146 0
NSG1_ENST00000513555 NSG1 P42857 Neuronal vesicle trafficking-associated protein 1 chr4 GO:0007268 Not Cancer Driver No 36 0.195 29 9 0.31 0
NTSR1 NTSR1 P30989 Neurotensin receptor type 1 chr20 GO:0007268 Not Cancer Driver No 85 0.203 23 1 0.043 0
OMP OMP P47874 Olfactory marker protein chr11 GO:0007268 Not Cancer Driver No 34 0.209 56 5 0.089 0
OPRK1_ENST00000520287 OPRK1 P41145 Kappa-type opioid receptor chr8 GO:0007268 Not Cancer Driver No 117 0.308 18 5 0.278 0
OR10H1_ENST00000334920 OR10H1 Q9Y4A9 Olfactory receptor 10H1 chr19 GO:0007268 Not Cancer Driver No 88 0.277 0 0 0.0 0
OR10H2 OR10H2 O60403 Olfactory receptor 10H2 chr19 GO:0007268 Not Cancer Driver No 90 0.286 0 0 0.0 0
OR10H3_ENST00000305892 OR10H3 O60404 Olfactory receptor 10H3 chr19 GO:0007268 Not Cancer Driver No 57 0.18 0 0 0.0 0
OR10H4 OR10H4 Q8NGA5 Olfactory receptor 10H4 chr19 GO:0007268 Not Cancer Driver No 76 0.241 0 0 0.0 0
OR10H5_ENST00000308940 OR10H5 Q8NGA6 Olfactory receptor 10H5 chr19 GO:0007268 Not Cancer Driver No 81 0.257 0 0 0.0 0
OR10J5 OR10J5 Q8NHC4 Olfactory receptor 10J5 chr1 GO:0007268 Not Cancer Driver No 95 0.307 0 0 0.0 0
OR11H4 OR11H4 Q8NGC9 Olfactory receptor 11H4 chr14 GO:0007268 Not Cancer Driver No 73 0.225 0 0 0.0 0
OR5T2 OR5T2 Q8NGG2 Olfactory receptor 5T2 chr11 GO:0007268 Not Cancer Driver No 167 0.465 0 0 0.0 0
OR5T3 OR5T3 Q8NGG3 Olfactory receptor 5T3 chr11 GO:0007268 Not Cancer Driver No 144 0.424 0 0 0.0 0
OR6T1 OR6T1 Q8NGN1 Olfactory receptor 6T1 chr11 GO:0007268 Not Cancer Driver No 125 0.387 0 0 0.0 0
PAFAH1B1 PAFAH1B1 P43034 Platelet-activating factor acetylhydrolase IB subunit beta chr17 GO:0007268 Not Cancer Driver No 42 0.102 82 11 0.134 7
PCDH8 PCDH8 O95206 Protocadherin-8 chr13 GO:0007268 Not Cancer Driver No 155 0.145 702 89 0.127 0
PCDHB10 PCDHB10 Q9UN67 Protocadherin beta-10 chr5 GO:0007268 Not Cancer Driver No 240 0.3 124 31 0.25 0
PCDHB11 PCDHB11 Q9Y5F2 Protocadherin beta-11 chr5 GO:0007268 Not Cancer Driver No 230 0.289 91 19 0.209 0
PCDHB13 PCDHB13 Q9Y5F0 Protocadherin beta-13 chr5 GO:0007268 Not Cancer Driver No 205 0.257 115 30 0.261 0
PCDHB14 PCDHB14 Q9Y5E9 Protocadherin beta-14 chr5 GO:0007268 Not Cancer Driver No 220 0.276 60 15 0.25 0
PCDHB16 PCDHB16 Q9NRJ7 Protocadherin beta-16 chr5 GO:0007268 Not Cancer Driver No 214 0.276 247 70 0.283 0
PCDHB2 PCDHB2 Q9Y5E7 Protocadherin beta-2 chr5 GO:0007268 Not Cancer Driver No 258 0.323 78 18 0.231 0
PCDHB3 PCDHB3 Q9Y5E6 Protocadherin beta-3 chr5 GO:0007268 Not Cancer Driver No 258 0.324 119 30 0.252 0
PCDHB4 PCDHB4 Q9Y5E5 Protocadherin beta-4 chr5 GO:0007268 Not Cancer Driver No 249 0.313 125 33 0.264 0
PCDHB5 PCDHB5 Q9Y5E4 Protocadherin beta-5 chr5 GO:0007268 Not Cancer Driver No 271 0.341 185 61 0.33 0
PCDHB6 PCDHB6 Q9Y5E3 Protocadherin beta-6 chr5 GO:0007268 Not Cancer Driver No 262 0.33 142 39 0.275 0
PCDHB9 PCDHB9 Q9Y5E1 Protocadherin beta-9 chr5 GO:0007268 Not Cancer Driver No 84 0.105 127 15 0.118 0
PDE7B PDE7B Q9NP56 cAMP-specific 3',5'-cyclic phosphodiesterase 7B chr6 GO:0007268 Not Cancer Driver No 74 0.164 47 7 0.149 0
PDLIM4 PDLIM4 P50479 PDZ and LIM domain protein 4 chr5 GO:0007268 Not Cancer Driver No 42 0.127 238 28 0.118 0
PDYN PDYN P01213 Proenkephalin-B chr20 GO:0007268 Not Cancer Driver No 124 0.488 111 61 0.55 8
PENK_ENST00000451791 PENK P01210 Proenkephalin-A chr8 GO:0007268 Not Cancer Driver No 109 0.408 142 62 0.437 0
PLP1 PLP1 P60201 Myelin proteolipid protein chrX GO:0007268 Not Cancer Driver No 49 0.177 5 1 0.2 72
PMCH PMCH P20382 Pro-MCH chr12 GO:0007268 Not Cancer Driver No 22 0.133 63 8 0.127 0
PMP22_ENST00000612492 PMP22 Q01453 Peripheral myelin protein 22 chr17 GO:0007268 Not Cancer Driver No 20 0.125 0 0 0.0 37
PNOC PNOC Q13519 Prepronociceptin chr8 GO:0007268 Not Cancer Driver No 20 0.114 78 10 0.128 0
PRKCG PRKCG P05129 Protein kinase C gamma type chr19 GO:0007268 Not Cancer Driver No 172 0.247 151 43 0.285 5
PTCHD1 PTCHD1 Q96NR3 Patched domain-containing protein 1 chrX GO:0007268 Not Cancer Driver No 154 0.173 11 6 0.545 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0007268 Census, Compendium Yes 505 1.253 76 4 0.053 41
PVALB_ENST00000417718 PVALB P20472 Parvalbumin alpha chr22 GO:0007268 Not Cancer Driver No 19 0.173 9 1 0.111 0
RAC3 RAC3 P60763 Ras-related C3 botulinum toxin substrate 3 chr17 GO:0007268 Not Cancer Driver No 24 0.125 0 0 0.0 4
RAPSN RAPSN Q13702 43 kDa receptor-associated protein of the synapse chr11 GO:0007268 Not Cancer Driver No 38 0.092 10 0 0.0 8
RASD2 RASD2 Q96D21 GTP-binding protein Rhes chr22 GO:0007268 Not Cancer Driver No 59 0.222 14 2 0.143 0
RIT2 RIT2 Q99578 GTP-binding protein Rit2 chr18 GO:0007268 Not Cancer Driver No 74 0.341 29 11 0.379 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0007268 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0007268 Not Cancer Driver No 133 0.181 91 15 0.165 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0007268 Compendium Yes 106 0.143 145 18 0.124 13
SCN2B SCN2B O60939 Sodium channel subunit beta-2 chr11 GO:0007268 Not Cancer Driver No 46 0.214 52 7 0.135 2
SDCBP_ENST00000260130 SDCBP O00560 Syntenin-1 chr8 GO:0007268 Not Cancer Driver No 39 0.131 17 2 0.118 0
SHISA6_ENST00000409168 SHISA6 Q6ZSJ9 Protein shisa-6 chr17 GO:0007268 Not Cancer Driver No 29 0.058 330 22 0.067 0
SLC12A4_ENST00000316341 SLC12A4 Q9UP95 Solute carrier family 12 member 4 chr16 GO:0007268 Not Cancer Driver No 122 0.112 171 17 0.099 0
SLC12A5 SLC12A5 Q9H2X9 Solute carrier family 12 member 5 chr20 GO:0007268 Not Cancer Driver No 263 0.231 290 59 0.203 5
SLC12A6_ENST00000558667 SLC12A6 Q9UHW9 Solute carrier family 12 member 6 chr15 GO:0007268 Not Cancer Driver No 168 0.146 280 46 0.164 0
SLC12A7 SLC12A7 Q9Y666 Solute carrier family 12 member 7 chr5 GO:0007268 Not Cancer Driver No 153 0.141 202 23 0.114 0
SLC18A2_ENST00000644641 SLC18A2 Q05940 Synaptic vesicular amine transporter chr10 GO:0007268 Not Cancer Driver No 105 0.204 23 7 0.304 1
SLC18A3 SLC18A3 Q16572 Vesicular acetylcholine transporter chr10 GO:0007268 Not Cancer Driver No 125 0.235 90 23 0.256 2
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0007268 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC1A2 SLC1A2 P43004 Excitatory amino acid transporter 2 chr11 GO:0007268 Not Cancer Driver No 77 0.134 81 7 0.086 3
SLC1A3 SLC1A3 P43003 Excitatory amino acid transporter 1 chr5 GO:0007268 Not Cancer Driver No 100 0.185 55 9 0.164 1
SLC1A6 SLC1A6 P48664 Excitatory amino acid transporter 4 chr19 GO:0007268 Not Cancer Driver No 168 0.298 50 20 0.4 0
SLC6A1_ENST00000643498 SLC6A1 P30531 Sodium- and chloride-dependent GABA transporter 1 chr3 GO:0007268 Not Cancer Driver No 119 0.199 24 9 0.375 4
SLC6A2_ENST00000568943 SLC6A2 P23975 Sodium-dependent noradrenaline transporter chr16 GO:0007268 Not Cancer Driver No 127 0.206 23 8 0.348 1
SLC6A5 SLC6A5 Q9Y345 Sodium- and chloride-dependent glycine transporter 2 chr11 GO:0007268 Not Cancer Driver No 181 0.227 169 38 0.225 7
SLITRK3 SLITRK3 O94933 SLIT and NTRK-like protein 3 chr3 GO:0007268 Not Cancer Driver No 335 0.343 321 127 0.396 0
SNAP25 SNAP25 P60880 Synaptosomal-associated protein 25 chr20 GO:0007268 Not Cancer Driver No 61 0.296 176 49 0.278 1
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0007268 Not Cancer Driver No 21 0.15 107 13 0.121 5
SNCB_ENST00000510387 SNCB Q16143 Beta-synuclein chr5 GO:0007268 Not Cancer Driver No 23 0.172 110 21 0.191 0
SNCG SNCG O76070 Gamma-synuclein chr10 GO:0007268 Not Cancer Driver No 11 0.087 111 10 0.09 0
SPG11 SPG11 Q96JI7 Spatacsin chr15 GO:0007268 Not Cancer Driver No 252 0.103 126 12 0.095 1
SST SST P61278 Somatostatin chr3 GO:0007268 Not Cancer Driver No 25 0.216 40 15 0.375 0
SV2B SV2B Q7L1I2 Synaptic vesicle glycoprotein 2B chr15 GO:0007268 Not Cancer Driver No 143 0.209 97 31 0.32 0
SV2C SV2C Q496J9 Synaptic vesicle glycoprotein 2C chr5 GO:0007268 Not Cancer Driver No 155 0.213 134 33 0.246 0
SYN1 SYN1 P17600 Synapsin-1 chrX GO:0007268 Not Cancer Driver No 75 0.106 445 27 0.061 0
SYN2 SYN2 Q92777 Synapsin-2 chr3 GO:0007268 Not Cancer Driver No 56 0.096 295 21 0.071 0
SYNJ2BP SYNJ2BP P57105 Synaptojanin-2-binding protein chr14 GO:0007268 Not Cancer Driver No 27 0.186 12 4 0.333 0
SYPL1 SYPL1 Q16563 Synaptophysin-like protein 1 chr7 GO:0007268 Not Cancer Driver No 31 0.12 17 3 0.176 0
SYT10 SYT10 Q6XYQ8 Synaptotagmin-10 chr12 GO:0007268 Not Cancer Driver No 155 0.296 163 56 0.344 0
SYT1_ENST00000393240 SYT1 P21579 Synaptotagmin-1 chr12 GO:0007268 Not Cancer Driver No 104 0.246 103 36 0.35 5
SYT5 SYT5 O00445 Synaptotagmin-5 chr19 GO:0007268 Not Cancer Driver No 60 0.155 110 11 0.1 0
TAC1 TAC1 P20366 Protachykinin-1 chr7 GO:0007268 Not Cancer Driver No 31 0.24 18 4 0.222 0
TH TH P07101 Tyrosine 3-monooxygenase chr11 GO:0007268 Not Cancer Driver No 61 0.116 149 21 0.141 38
TMOD2 TMOD2 Q9NZR1 Tropomodulin-2 chr15 GO:0007268 Not Cancer Driver No 33 0.094 216 22 0.102 0
TPBG_ENST00000543496 TPBG Q13641 Trophoblast glycoprotein chr6 GO:0007268 Not Cancer Driver No 58 0.138 13 1 0.077 0
TPGS1 TPGS1 Q6ZTW0 Tubulin polyglutamylase complex subunit 1 chr19 GO:0007268 Not Cancer Driver No 6 0.021 62 2 0.032 0
UNC119 UNC119 Q13432 Protein unc-119 homolog A chr17 GO:0007268 Not Cancer Driver No 20 0.083 89 4 0.045 1
UNC13B_ENST00000378495 UNC13B O14795 Protein unc-13 homolog B chr9 GO:0007268 Not Cancer Driver No 214 0.135 448 77 0.172 0
UNC13C UNC13C Q8NB66 Protein unc-13 homolog C chr15 GO:0007268 Not Cancer Driver No 681 0.308 886 268 0.302 0
USP14 USP14 P54578 Ubiquitin carboxyl-terminal hydrolase 14 chr18 GO:0007268 Not Cancer Driver No 59 0.119 86 6 0.07 0
UTS2_ENST00000361696 UTS2 O95399 Urotensin-2 chr1 GO:0007268 Not Cancer Driver No 16 0.129 0 0 0.0 0
ZACN ZACN Q401N2 Zinc-activated ligand-gated ion channel chr17 GO:0007268 Not Cancer Driver No 46 0.112 48 6 0.125 0