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Total number of protein in "GO:0007254" GO term:  47

Identifier
UniProt Gene
UniProt Accession
UniProt Name
Chromosome
GO term
Database
Cancer Driver
Number of missense mutations
Missense mutation per residues
Number of disordered residues
Number of mutations in disordered regions
Disordered missense mutations per residues
Number of OMIM mutation
ADORA2B ADORA2B P29275 Adenosine receptor A2b chr17 GO:0007254 Not Cancer Driver No 23 0.069 0 0 0.0 0
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX GO:0007254 Not Cancer Driver No 158 0.204 223 45 0.202 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0007254 Not Cancer Driver No 65 0.129 451 58 0.129 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0007254 Not Cancer Driver No 304 0.282 189 60 0.317 108
CDC42EP5 CDC42EP5 Q6NZY7 Cdc42 effector protein 5 chr19 GO:0007254 Not Cancer Driver No 4 0.027 147 4 0.027 0
CRKL CRKL P46109 Crk-like protein chr22 GO:0007254 Not Cancer Driver No 38 0.125 160 25 0.156 0
DAXX_ENST00000266000 DAXX Q9UER7 Death domain-associated protein 6 chr6 GO:0007254 Census, Compendium Yes 106 0.143 549 81 0.148 0
DUSP9 DUSP9 Q99956 Dual specificity protein phosphatase 9 chrX GO:0007254 Not Cancer Driver No 40 0.104 109 12 0.11 0
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0007254 Not Cancer Driver No 211 0.141 829 117 0.141 9
GPS1_ENST00000306823 GPS1 Q13098 COP9 signalosome complex subunit 1 chr17 GO:0007254 Not Cancer Driver No 62 0.126 106 14 0.132 0
GPS2 GPS2 Q13227 G protein pathway suppressor 2 chr17 GO:0007254 Not Cancer Driver No 29 0.089 319 26 0.082 0
HACD3 HACD3 Q9P035 Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 chr15 GO:0007254 Not Cancer Driver No 28 0.077 10 0 0.0 0
IRAK1 IRAK1 P51617 Interleukin-1 receptor-associated kinase 1 chrX GO:0007254 Compendium Yes 71 0.1 337 39 0.116 0
IRAK4_ENST00000551736 IRAK4 Q9NWZ3 Interleukin-1 receptor-associated kinase 4 chr12 GO:0007254 Not Cancer Driver No 68 0.148 116 20 0.172 2
LRRK2 LRRK2 Q5S007 Leucine-rich repeat serine/threonine-protein kinase 2 chr12 GO:0007254 Not Cancer Driver No 519 0.205 90 17 0.189 23
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0007254 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0007254 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0007254 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K11 MAP3K11 Q16584 Mitogen-activated protein kinase kinase kinase 11 chr11 GO:0007254 Not Cancer Driver No 97 0.115 466 54 0.116 0
MAP3K12_ENST00000267079 MAP3K12 Q12852 Mitogen-activated protein kinase kinase kinase 12 chr12 GO:0007254 Not Cancer Driver No 120 0.14 481 64 0.133 0
MAP3K13_ENST00000424227 MAP3K13 O43283 Mitogen-activated protein kinase kinase kinase 13 chr3 GO:0007254 Census Yes 157 0.163 593 91 0.153 0
MAP3K20 MAP3K20 Q9NYL2 Mitogen-activated protein kinase kinase kinase 20 chr2 GO:0007254 Not Cancer Driver No 101 0.126 294 41 0.139 1
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0007254 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0007254 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP4K1 MAP4K1 Q92918 Mitogen-activated protein kinase kinase kinase kinase 1 chr19 GO:0007254 Not Cancer Driver No 116 0.139 276 41 0.149 0
MAP4K2 MAP4K2 Q12851 Mitogen-activated protein kinase kinase kinase kinase 2 chr11 GO:0007254 Not Cancer Driver No 78 0.095 243 23 0.095 0
MAP4K3 MAP4K3 Q8IVH8 Mitogen-activated protein kinase kinase kinase kinase 3 chr2 GO:0007254 Not Cancer Driver No 116 0.13 313 45 0.144 0
MAPK10_ENST00000515650 MAPK10 P53779 Mitogen-activated protein kinase 10 chr4 GO:0007254 Not Cancer Driver No 88 0.19 107 16 0.15 0
MAPK8IP2 MAPK8IP2 Q13387 C-Jun-amino-terminal kinase-interacting protein 2 chr22 GO:0007254 Not Cancer Driver No 49 0.059 568 27 0.048 0
MAPK8_ENST00000374189 MAPK8 P45983 Mitogen-activated protein kinase 8 chr10 GO:0007254 Not Cancer Driver No 64 0.15 94 9 0.096 0
MAPK9 MAPK9 P45984 Mitogen-activated protein kinase 9 chr5 GO:0007254 Not Cancer Driver No 59 0.139 90 8 0.089 0
MINK1 MINK1 Q8N4C8 Misshapen-like kinase 1 chr17 GO:0007254 Not Cancer Driver No 113 0.085 740 56 0.076 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0007254 Census, Compendium Yes 37 0.125 47 1 0.021 2
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0007254 Not Cancer Driver No 104 0.107 344 38 0.11 0
NPHS1 NPHS1 O60500 Nephrin chr19 GO:0007254 Not Cancer Driver No 230 0.185 484 108 0.223 62
PTGER4 PTGER4 P35408 Prostaglandin E2 receptor EP4 subtype chr5 GO:0007254 Not Cancer Driver No 81 0.166 118 17 0.144 0
ROR2 ROR2 Q01974 Tyrosine-protein kinase transmembrane receptor ROR2 chr9 GO:0007254 Not Cancer Driver No 203 0.215 299 71 0.237 5
SH2D3A SH2D3A Q9BRG2 SH2 domain-containing protein 3A chr19 GO:0007254 Not Cancer Driver No 68 0.118 305 40 0.131 0
SH2D3C SH2D3C Q8N5H7 SH2 domain-containing protein 3C chr9 GO:0007254 Not Cancer Driver No 110 0.128 440 72 0.164 0
SMAD3 SMAD3 P84022 Mothers against decapentaplegic homolog 3 chr15 GO:0007254 Census, Compendium Yes 97 0.228 111 19 0.171 5
STRADB STRADB Q9C0K7 STE20-related kinase adapter protein beta chr2 GO:0007254 Not Cancer Driver No 53 0.127 84 7 0.083 0
TLR3 TLR3 O15455 Toll-like receptor 3 chr4 GO:0007254 Not Cancer Driver No 123 0.136 0 0 0.0 1
TLR7 TLR7 Q9NYK1 Toll-like receptor 7 chrX GO:0007254 Not Cancer Driver No 182 0.173 14 1 0.071 1
TNF TNF P01375 Tumor necrosis factor chr6 GO:0007254 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFRSF19 TNFRSF19 Q9NS68 Tumor necrosis factor receptor superfamily member 19 chr13 GO:0007254 Not Cancer Driver No 72 0.17 103 19 0.184 0
TRIB1 TRIB1 Q96RU8 Tribbles homolog 1 chr8 GO:0007254 Not Cancer Driver No 47 0.126 91 5 0.055 0
WNT5A_ENST00000474267 WNT5A P41221 Protein Wnt-5a chr3 GO:0007254 Not Cancer Driver No 66 0.174 0 0 0.0 2