Total number of protein in "GO:0007200" GO term: 75
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACTN2_ENST00000366578 | ACTN2 | P35609 | Alpha-actinin-2 | chr1 | GO:0007200 | Not Cancer Driver | No | 227 | 0.254 | 131 | 29 | 0.221 | 9 |
| ADRA1A_ENST00000380573 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0007200 | Not Cancer Driver | No | 130 | 0.279 | 40 | 8 | 0.2 | 0 |
| ADRA1B | ADRA1B | P35368 | Alpha-1B adrenergic receptor | chr5 | GO:0007200 | Not Cancer Driver | No | 53 | 0.102 | 132 | 1 | 0.008 | 0 |
| ADRA1D | ADRA1D | P25100 | Alpha-1D adrenergic receptor | chr20 | GO:0007200 | Not Cancer Driver | No | 62 | 0.108 | 189 | 19 | 0.101 | 0 |
| ADRA2A | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0007200 | Not Cancer Driver | No | 67 | 0.144 | 161 | 10 | 0.062 | 0 |
| AGT | AGT | P01019 | Angiotensinogen | chr1 | GO:0007200 | Not Cancer Driver | No | 85 | 0.179 | 33 | 10 | 0.303 | 1 |
| AGTR1_ENST00000349243 | AGTR1 | P30556 | Type-1 angiotensin II receptor | chr3 | GO:0007200 | Not Cancer Driver | No | 95 | 0.265 | 0 | 0 | 0.0 | 1 |
| ANO1 | ANO1 | Q5XXA6 | Anoctamin-1 | chr11 | GO:0007200 | Not Cancer Driver | No | 155 | 0.157 | 168 | 14 | 0.083 | 0 |
| C3AR1 | C3AR1 | Q16581 | C3a anaphylatoxin chemotactic receptor | chr12 | GO:0007200 | Not Cancer Driver | No | 88 | 0.183 | 72 | 16 | 0.222 | 0 |
| C5AR1 | C5AR1 | P21730 | C5a anaphylatoxin chemotactic receptor 1 | chr19 | GO:0007200 | Not Cancer Driver | No | 71 | 0.203 | 0 | 0 | 0.0 | 0 |
| C5AR2_ENST00000600626 | C5AR2 | Q9P296 | C5a anaphylatoxin chemotactic receptor 2 | chr19 | GO:0007200 | Not Cancer Driver | No | 60 | 0.178 | 11 | 3 | 0.273 | 0 |
| CASR_ENST00000638421 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | GO:0007200 | Not Cancer Driver | No | 304 | 0.282 | 189 | 60 | 0.317 | 108 |
| CCKAR | CCKAR | P32238 | Cholecystokinin receptor type A | chr4 | GO:0007200 | Not Cancer Driver | No | 107 | 0.25 | 49 | 14 | 0.286 | 0 |
| CCKBR | CCKBR | P32239 | Gastrin/cholecystokinin type B receptor | chr11 | GO:0007200 | Not Cancer Driver | No | 122 | 0.273 | 61 | 22 | 0.361 | 0 |
| CHRM1 | CHRM1 | P11229 | Muscarinic acetylcholine receptor M1 | chr11 | GO:0007200 | Not Cancer Driver | No | 63 | 0.137 | 131 | 24 | 0.183 | 0 |
| CHRM2_ENST00000320658 | CHRM2 | P08172 | Muscarinic acetylcholine receptor M2 | chr7 | GO:0007200 | Not Cancer Driver | No | 218 | 0.468 | 169 | 93 | 0.55 | 0 |
| CMKLR1 | CMKLR1 | Q99788 | Chemerin-like receptor 1 | chr12 | GO:0007200 | Not Cancer Driver | No | 107 | 0.287 | 24 | 13 | 0.542 | 0 |
| CX3CR1_ENST00000542107 | CX3CR1 | P49238 | CX3C chemokine receptor 1 | chr3 | GO:0007200 | Not Cancer Driver | No | 80 | 0.225 | 0 | 0 | 0.0 | 0 |
| CXCR2 | CXCR2 | P25025 | C-X-C chemokine receptor type 2 | chr2 | GO:0007200 | Not Cancer Driver | No | 87 | 0.242 | 8 | 0 | 0.0 | 0 |
| DRD1 | DRD1 | P21728 | D(1A) dopamine receptor | chr5 | GO:0007200 | Not Cancer Driver | No | 73 | 0.164 | 30 | 4 | 0.133 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0007200 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0007200 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
| DRD5 | DRD5 | P21918 | D(1B) dopamine receptor | chr4 | GO:0007200 | Not Cancer Driver | No | 172 | 0.361 | 29 | 18 | 0.621 | 0 |
| EDNRB_ENST00000334286 | EDNRB | P24530 | Endothelin receptor type B | chr13 | GO:0007200 | Not Cancer Driver | No | 112 | 0.253 | 56 | 19 | 0.339 | 6 |
| ESR1_ENST00000206249 | ESR1 | P03372 | Estrogen receptor | chr6 | GO:0007200 | Census, Compendium | Yes | 121 | 0.203 | 195 | 27 | 0.138 | 2 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0007200 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| F2RL3 | F2RL3 | Q96RI0 | Proteinase-activated receptor 4 | chr19 | GO:0007200 | Not Cancer Driver | No | 43 | 0.112 | 46 | 4 | 0.087 | 0 |
| FFAR4_ENST00000371481 | FFAR4 | Q5NUL3 | Free fatty acid receptor 4 | chr10 | GO:0007200 | Not Cancer Driver | No | 47 | 0.13 | 0 | 0 | 0.0 | 0 |
| FPR1_ENST00000304748 | FPR1 | P21462 | fMet-Leu-Phe receptor | chr19 | GO:0007200 | Not Cancer Driver | No | 99 | 0.283 | 18 | 3 | 0.167 | 0 |
| FPR2 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0007200 | Not Cancer Driver | No | 96 | 0.274 | 26 | 5 | 0.192 | 0 |
| FPR3 | FPR3 | P25089 | N-formyl peptide receptor 3 | chr19 | GO:0007200 | Not Cancer Driver | No | 82 | 0.232 | 28 | 2 | 0.071 | 0 |
| GALR2 | GALR2 | O43603 | Galanin receptor type 2 | chr17 | GO:0007200 | Not Cancer Driver | No | 40 | 0.103 | 0 | 0 | 0.0 | 0 |
| GNA11 | GNA11 | P29992 | Guanine nucleotide-binding protein subunit alpha-11 | chr19 | GO:0007200 | Census, Compendium | Yes | 48 | 0.134 | 10 | 0 | 0.0 | 5 |
| GNA14 | GNA14 | O95837 | Guanine nucleotide-binding protein subunit alpha-14 | chr9 | GO:0007200 | Not Cancer Driver | No | 62 | 0.175 | 11 | 2 | 0.182 | 0 |
| GNA15 | GNA15 | P30679 | Guanine nucleotide-binding protein subunit alpha-15 | chr19 | GO:0007200 | Not Cancer Driver | No | 51 | 0.136 | 15 | 6 | 0.4 | 0 |
| GNB1_ENST00000378609 | GNB1 | P62873 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | chr1 | GO:0007200 | Not Cancer Driver | No | 45 | 0.132 | 24 | 2 | 0.083 | 16 |
| GNG13 | GNG13 | Q9P2W3 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 | chr16 | GO:0007200 | Not Cancer Driver | No | 17 | 0.254 | 12 | 2 | 0.167 | 0 |
| GPR139 | GPR139 | Q6DWJ6 | Probable G-protein coupled receptor 139 | chr16 | GO:0007200 | Not Cancer Driver | No | 116 | 0.329 | 1 | 1 | 1.0 | 0 |
| GPR32 | GPR32 | O75388 | Probable G-protein coupled receptor 32 | chr19 | GO:0007200 | Not Cancer Driver | No | 85 | 0.239 | 18 | 6 | 0.333 | 0 |
| GPR4 | GPR4 | P46093 | G-protein coupled receptor 4 | chr19 | GO:0007200 | Not Cancer Driver | No | 57 | 0.157 | 44 | 8 | 0.182 | 0 |
| GRM5 | GRM5 | P41594 | Metabotropic glutamate receptor 5 | chr11 | GO:0007200 | Not Cancer Driver | No | 312 | 0.257 | 323 | 51 | 0.158 | 0 |
| GRPR | GRPR | P30550 | Gastrin-releasing peptide receptor | chrX | GO:0007200 | Not Cancer Driver | No | 65 | 0.169 | 0 | 0 | 0.0 | 0 |
| HCRT | HCRT | O43612 | Orexin | chr17 | GO:0007200 | Not Cancer Driver | No | 3 | 0.023 | 45 | 0 | 0.0 | 1 |
| HCRTR2 | HCRTR2 | O43614 | Orexin receptor type 2 | chr6 | GO:0007200 | Not Cancer Driver | No | 154 | 0.347 | 38 | 13 | 0.342 | 0 |
| HOMER1 | HOMER1 | Q86YM7 | Homer protein homolog 1 | chr5 | GO:0007200 | Not Cancer Driver | No | 46 | 0.13 | 243 | 32 | 0.132 | 0 |
| HRH1_ENST00000438284 | HRH1 | P35367 | Histamine H1 receptor | chr3 | GO:0007200 | Not Cancer Driver | No | 96 | 0.197 | 122 | 26 | 0.213 | 0 |
| HTR2A | HTR2A | P28223 | 5-hydroxytryptamine receptor 2A | chr13 | GO:0007200 | Not Cancer Driver | No | 105 | 0.223 | 44 | 8 | 0.182 | 0 |
| HTR2B | HTR2B | P41595 | 5-hydroxytryptamine receptor 2B | chr2 | GO:0007200 | Not Cancer Driver | No | 41 | 0.085 | 23 | 2 | 0.087 | 0 |
| HTR2C | HTR2C | P28335 | 5-hydroxytryptamine receptor 2C | chrX | GO:0007200 | Not Cancer Driver | No | 140 | 0.306 | 40 | 11 | 0.275 | 0 |
| LHCGR | LHCGR | P22888 | Lutropin-choriogonadotropic hormone receptor | chr2 | GO:0007200 | Not Cancer Driver | No | 181 | 0.259 | 12 | 8 | 0.667 | 25 |
| LTB4R_ENST00000396782 | LTB4R | Q15722 | Leukotriene B4 receptor 1 | chr14 | GO:0007200 | Not Cancer Driver | No | 34 | 0.097 | 40 | 0 | 0.0 | 0 |
| MC3R | MC3R | P41968 | Melanocortin receptor 3 | chr20 | GO:0007200 | Not Cancer Driver | No | 96 | 0.297 | 0 | 0 | 0.0 | 0 |
| NMBR | NMBR | P28336 | Neuromedin-B receptor | chr6 | GO:0007200 | Not Cancer Driver | No | 89 | 0.228 | 9 | 1 | 0.111 | 0 |
| NMUR1 | NMUR1 | Q9HB89 | Neuromedin-U receptor 1 | chr2 | GO:0007200 | Not Cancer Driver | No | 79 | 0.185 | 15 | 5 | 0.333 | 0 |
| NMUR2 | NMUR2 | Q9GZQ4 | Neuromedin-U receptor 2 | chr5 | GO:0007200 | Not Cancer Driver | No | 139 | 0.335 | 5 | 1 | 0.2 | 0 |
| NPR3 | NPR3 | P17342 | Atrial natriuretic peptide receptor 3 | chr5 | GO:0007200 | Not Cancer Driver | No | 95 | 0.176 | 58 | 8 | 0.138 | 0 |
| NTSR2 | NTSR2 | O95665 | Neurotensin receptor type 2 | chr2 | GO:0007200 | Not Cancer Driver | No | 73 | 0.178 | 55 | 3 | 0.055 | 0 |
| OPRD1 | OPRD1 | P41143 | Delta-type opioid receptor | chr1 | GO:0007200 | Not Cancer Driver | No | 91 | 0.245 | 30 | 3 | 0.1 | 0 |
| OPRK1_ENST00000520287 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0007200 | Not Cancer Driver | No | 117 | 0.308 | 18 | 5 | 0.278 | 0 |
| OPRM1_ENST00000330432 | OPRM1 | P35372 | Mu-type opioid receptor | chr6 | GO:0007200 | Not Cancer Driver | No | 107 | 0.268 | 58 | 27 | 0.466 | 0 |
| P2RY1 | P2RY1 | P47900 | P2Y purinoceptor 1 | chr3 | GO:0007200 | Not Cancer Driver | No | 60 | 0.161 | 16 | 1 | 0.062 | 0 |
| P2RY11 | P2RY11 | Q96G91 | P2Y purinoceptor 11 | chr19 | GO:0007200 | Not Cancer Driver | No | 47 | 0.126 | 31 | 1 | 0.032 | 0 |
| P2RY12 | P2RY12 | Q9H244 | P2Y purinoceptor 12 | chr3 | GO:0007200 | Not Cancer Driver | No | 57 | 0.167 | 21 | 2 | 0.095 | 3 |
| P2RY2_ENST00000393596 | P2RY2 | P41231 | P2Y purinoceptor 2 | chr11 | GO:0007200 | Not Cancer Driver | No | 67 | 0.178 | 60 | 13 | 0.217 | 0 |
| P2RY4 | P2RY4 | P51582 | P2Y purinoceptor 4 | chrX | GO:0007200 | Not Cancer Driver | No | 66 | 0.181 | 10 | 2 | 0.2 | 0 |
| P2RY6_ENST00000540342 | P2RY6 | Q15077 | P2Y purinoceptor 6 | chr11 | GO:0007200 | Not Cancer Driver | No | 50 | 0.152 | 10 | 5 | 0.5 | 0 |
| PLCB2 | PLCB2 | Q00722 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 | chr15 | GO:0007200 | Not Cancer Driver | No | 161 | 0.136 | 495 | 51 | 0.103 | 0 |
| PLCE1 | PLCE1 | Q9P212 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 | chr10 | GO:0007200 | Not Cancer Driver | No | 367 | 0.159 | 780 | 107 | 0.137 | 1 |
| PTGER3_ENST00000370931 | PTGER3 | P43115 | Prostaglandin E2 receptor EP3 subtype | chr1 | GO:0007200 | Not Cancer Driver | No | 79 | 0.203 | 17 | 2 | 0.118 | 0 |
| PTH1R_ENST00000449590 | PTH1R | Q03431 | Parathyroid hormone/parathyroid hormone-related peptide receptor | chr3 | GO:0007200 | Not Cancer Driver | No | 86 | 0.145 | 124 | 25 | 0.202 | 5 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0007200 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| TACR1 | TACR1 | P25103 | Substance-P receptor | chr2 | GO:0007200 | Not Cancer Driver | No | 69 | 0.17 | 28 | 2 | 0.071 | 0 |
| TGM2 | TGM2 | P21980 | Protein-glutamine gamma-glutamyltransferase 2 | chr20 | GO:0007200 | Not Cancer Driver | No | 123 | 0.179 | 107 | 26 | 0.243 | 0 |
| TRHR | TRHR | P34981 | Thyrotropin-releasing hormone receptor | chr8 | GO:0007200 | Not Cancer Driver | No | 104 | 0.261 | 13 | 0 | 0.0 | 2 |
| VIP | VIP | P01282 | VIP peptides | chr6 | GO:0007200 | Not Cancer Driver | No | 58 | 0.341 | 77 | 25 | 0.325 | 0 |