Total number of protein in "GO:0007193" GO term: 74
Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADCY5 | ADCY5 | O95622 | Adenylate cyclase type 5 | chr3 | GO:0007193 | Not Cancer Driver | No | 234 | 0.186 | 268 | 23 | 0.086 | 2 |
ADCY6 | ADCY6 | O43306 | Adenylate cyclase type 6 | chr12 | GO:0007193 | Not Cancer Driver | No | 144 | 0.123 | 147 | 17 | 0.116 | 1 |
ADORA1 | ADORA1 | P30542 | Adenosine receptor A1 | chr1 | GO:0007193 | Not Cancer Driver | No | 64 | 0.196 | 12 | 4 | 0.333 | 0 |
ADRA2A | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0007193 | Not Cancer Driver | No | 67 | 0.144 | 161 | 10 | 0.062 | 0 |
AKAP12 | AKAP12 | Q02952 | A-kinase anchor protein 12 | chr6 | GO:0007193 | Not Cancer Driver | No | 215 | 0.121 | 1770 | 214 | 0.121 | 0 |
AKAP5_ENST00000320636 | AKAP5 | P24588 | A-kinase anchor protein 5 | chr14 | GO:0007193 | Not Cancer Driver | No | 37 | 0.087 | 405 | 34 | 0.084 | 0 |
CASR_ENST00000638421 | CASR | P41180 | Extracellular calcium-sensing receptor | chr3 | GO:0007193 | Not Cancer Driver | No | 304 | 0.282 | 189 | 60 | 0.317 | 108 |
CHRM1 | CHRM1 | P11229 | Muscarinic acetylcholine receptor M1 | chr11 | GO:0007193 | Not Cancer Driver | No | 63 | 0.137 | 131 | 24 | 0.183 | 0 |
CHRM2_ENST00000320658 | CHRM2 | P08172 | Muscarinic acetylcholine receptor M2 | chr7 | GO:0007193 | Not Cancer Driver | No | 218 | 0.468 | 169 | 93 | 0.55 | 0 |
CHRM3_ENST00000615928 | CHRM3 | P20309 | Muscarinic acetylcholine receptor M3 | chr1 | GO:0007193 | Not Cancer Driver | No | 182 | 0.308 | 136 | 42 | 0.309 | 0 |
CHRM4 | CHRM4 | P08173 | Muscarinic acetylcholine receptor M4 | chr11 | GO:0007193 | Not Cancer Driver | No | 75 | 0.157 | 143 | 27 | 0.189 | 0 |
CHRM5 | CHRM5 | P08912 | Muscarinic acetylcholine receptor M5 | chr15 | GO:0007193 | Not Cancer Driver | No | 74 | 0.139 | 155 | 20 | 0.129 | 0 |
CORT | CORT | O00230 | Cortistatin | chr1 | GO:0007193 | Not Cancer Driver | No | 11 | 0.105 | 46 | 4 | 0.087 | 0 |
DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0007193 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0007193 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
DRD4 | DRD4 | P21917 | D(4) dopamine receptor | chr11 | GO:0007193 | Not Cancer Driver | No | 26 | 0.062 | 109 | 0 | 0.0 | 0 |
EDN1 | EDN1 | P05305 | Endothelin-1 | chr6 | GO:0007193 | Not Cancer Driver | No | 37 | 0.175 | 97 | 20 | 0.206 | 3 |
EDNRA | EDNRA | P25101 | Endothelin-1 receptor | chr4 | GO:0007193 | Not Cancer Driver | No | 62 | 0.145 | 21 | 6 | 0.286 | 2 |
FFAR3 | FFAR3 | O14843 | Free fatty acid receptor 3 | chr19 | GO:0007193 | Not Cancer Driver | No | 78 | 0.225 | 29 | 6 | 0.207 | 0 |
FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0007193 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
FPR2 | FPR2 | P25090 | N-formyl peptide receptor 2 | chr19 | GO:0007193 | Not Cancer Driver | No | 96 | 0.274 | 26 | 5 | 0.192 | 0 |
GABBR1 | GABBR1 | Q9UBS5 | Gamma-aminobutyric acid type B receptor subunit 1 | chr6 | GO:0007193 | Not Cancer Driver | No | 150 | 0.156 | 142 | 17 | 0.12 | 0 |
GABBR2 | GABBR2 | O75899 | Gamma-aminobutyric acid type B receptor subunit 2 | chr9 | GO:0007193 | Not Cancer Driver | No | 169 | 0.18 | 220 | 29 | 0.132 | 4 |
GNAI1 | GNAI1 | P63096 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | chr7 | GO:0007193 | Not Cancer Driver | No | 52 | 0.147 | 11 | 3 | 0.273 | 0 |
GNAI2 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | GO:0007193 | Compendium | Yes | 50 | 0.141 | 24 | 0 | 0.0 | 0 |
GNAI3 | GNAI3 | P08754 | Guanine nucleotide-binding protein G(i) subunit alpha-3 | chr1 | GO:0007193 | Not Cancer Driver | No | 42 | 0.119 | 11 | 0 | 0.0 | 1 |
GNAT1 | GNAT1 | P11488 | Guanine nucleotide-binding protein G(t) subunit alpha-1 | chr3 | GO:0007193 | Not Cancer Driver | No | 43 | 0.123 | 39 | 6 | 0.154 | 3 |
GNAZ | GNAZ | P19086 | Guanine nucleotide-binding protein G(z) subunit alpha | chr22 | GO:0007193 | Not Cancer Driver | No | 84 | 0.237 | 30 | 13 | 0.433 | 0 |
GPR176 | GPR176 | Q14439 | G-protein coupled receptor 176 | chr15 | GO:0007193 | Not Cancer Driver | No | 63 | 0.122 | 124 | 17 | 0.137 | 0 |
GPR37 | GPR37 | O15354 | Prosaposin receptor GPR37 | chr7 | GO:0007193 | Not Cancer Driver | No | 124 | 0.202 | 200 | 42 | 0.21 | 0 |
GPR37L1 | GPR37L1 | O60883 | G-protein coupled receptor 37-like 1 | chr1 | GO:0007193 | Not Cancer Driver | No | 62 | 0.129 | 81 | 8 | 0.099 | 0 |
GRIK3 | GRIK3 | Q13003 | Glutamate receptor ionotropic, kainate 3 | chr1 | GO:0007193 | Not Cancer Driver | No | 256 | 0.279 | 38 | 9 | 0.237 | 0 |
GRM1_ENST00000282753 | GRM1 | Q13255 | Metabotropic glutamate receptor 1 | chr6 | GO:0007193 | Not Cancer Driver | No | 346 | 0.29 | 339 | 91 | 0.268 | 3 |
GRM2 | GRM2 | Q14416 | Metabotropic glutamate receptor 2 | chr3 | GO:0007193 | Not Cancer Driver | No | 143 | 0.164 | 24 | 3 | 0.125 | 0 |
GRM3 | GRM3 | Q14832 | Metabotropic glutamate receptor 3 | chr7 | GO:0007193 | Census | Yes | 323 | 0.367 | 8 | 3 | 0.375 | 0 |
GRM4 | GRM4 | Q14833 | Metabotropic glutamate receptor 4 | chr6 | GO:0007193 | Not Cancer Driver | No | 187 | 0.205 | 74 | 22 | 0.297 | 0 |
GRM5 | GRM5 | P41594 | Metabotropic glutamate receptor 5 | chr11 | GO:0007193 | Not Cancer Driver | No | 312 | 0.257 | 323 | 51 | 0.158 | 0 |
GRM6_ENST00000517717 | GRM6 | O15303 | Metabotropic glutamate receptor 6 | chr5 | GO:0007193 | Not Cancer Driver | No | 200 | 0.228 | 113 | 23 | 0.204 | 6 |
GRM7 | GRM7 | Q14831 | Metabotropic glutamate receptor 7 | chr3 | GO:0007193 | Not Cancer Driver | No | 316 | 0.345 | 91 | 31 | 0.341 | 1 |
GRM8 | GRM8 | O00222 | Metabotropic glutamate receptor 8 | chr7 | GO:0007193 | Not Cancer Driver | No | 369 | 0.406 | 49 | 24 | 0.49 | 0 |
HRH3 | HRH3 | Q9Y5N1 | Histamine H3 receptor | chr20 | GO:0007193 | Not Cancer Driver | No | 65 | 0.146 | 93 | 10 | 0.108 | 0 |
HRH4 | HRH4 | Q9H3N8 | Histamine H4 receptor | chr18 | GO:0007193 | Not Cancer Driver | No | 72 | 0.185 | 1 | 1 | 1.0 | 0 |
HTR1A | HTR1A | P08908 | 5-hydroxytryptamine receptor 1A | chr5 | GO:0007193 | Not Cancer Driver | No | 170 | 0.403 | 100 | 49 | 0.49 | 0 |
HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | GO:0007193 | Not Cancer Driver | No | 91 | 0.233 | 33 | 15 | 0.455 | 0 |
HTR1D | HTR1D | P28221 | 5-hydroxytryptamine receptor 1D | chr1 | GO:0007193 | Not Cancer Driver | No | 54 | 0.143 | 24 | 1 | 0.042 | 0 |
HTR1E | HTR1E | P28566 | 5-hydroxytryptamine receptor 1E | chr6 | GO:0007193 | Not Cancer Driver | No | 133 | 0.364 | 18 | 5 | 0.278 | 0 |
HTR1F | HTR1F | P30939 | 5-hydroxytryptamine receptor 1F | chr3 | GO:0007193 | Not Cancer Driver | No | 83 | 0.227 | 3 | 0 | 0.0 | 0 |
HTR4_ENST00000377888 | HTR4 | Q13639 | 5-hydroxytryptamine receptor 4 | chr5 | GO:0007193 | Not Cancer Driver | No | 77 | 0.198 | 26 | 9 | 0.346 | 0 |
HTR5A | HTR5A | P47898 | 5-hydroxytryptamine receptor 5A | chr7 | GO:0007193 | Not Cancer Driver | No | 174 | 0.487 | 6 | 1 | 0.167 | 0 |
INSL3_ENST00000317306 | INSL3 | P51460 | Insulin-like 3 | chr19 | GO:0007193 | Not Cancer Driver | No | 18 | 0.137 | 34 | 12 | 0.353 | 3 |
LPAR1_ENST00000358883 | LPAR1 | Q92633 | Lysophosphatidic acid receptor 1 | chr9 | GO:0007193 | Not Cancer Driver | No | 79 | 0.217 | 21 | 6 | 0.286 | 0 |
MARCO | MARCO | Q9UEW3 | Macrophage receptor MARCO | chr2 | GO:0007193 | Not Cancer Driver | No | 180 | 0.346 | 323 | 125 | 0.387 | 0 |
MCHR1 | MCHR1 | Q99705 | Melanin-concentrating hormone receptor 1 | chr22 | GO:0007193 | Not Cancer Driver | No | 64 | 0.152 | 100 | 12 | 0.12 | 0 |
MTNR1A | MTNR1A | P48039 | Melatonin receptor type 1A | chr4 | GO:0007193 | Not Cancer Driver | No | 72 | 0.206 | 0 | 0 | 0.0 | 0 |
NPR3 | NPR3 | P17342 | Atrial natriuretic peptide receptor 3 | chr5 | GO:0007193 | Not Cancer Driver | No | 95 | 0.176 | 58 | 8 | 0.138 | 0 |
NPY1R | NPY1R | P25929 | Neuropeptide Y receptor type 1 | chr4 | GO:0007193 | Not Cancer Driver | No | 114 | 0.297 | 4 | 0 | 0.0 | 0 |
NPY2R | NPY2R | P49146 | Neuropeptide Y receptor type 2 | chr4 | GO:0007193 | Not Cancer Driver | No | 119 | 0.312 | 53 | 16 | 0.302 | 0 |
OPRD1 | OPRD1 | P41143 | Delta-type opioid receptor | chr1 | GO:0007193 | Not Cancer Driver | No | 91 | 0.245 | 30 | 3 | 0.1 | 0 |
OPRK1_ENST00000520287 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0007193 | Not Cancer Driver | No | 117 | 0.308 | 18 | 5 | 0.278 | 0 |
OPRL1_ENST00000336866 | OPRL1 | P41146 | Nociceptin receptor | chr20 | GO:0007193 | Not Cancer Driver | No | 81 | 0.219 | 0 | 0 | 0.0 | 0 |
OPRM1_ENST00000330432 | OPRM1 | P35372 | Mu-type opioid receptor | chr6 | GO:0007193 | Not Cancer Driver | No | 107 | 0.268 | 58 | 27 | 0.466 | 0 |
OXER1 | OXER1 | Q8TDS5 | Oxoeicosanoid receptor 1 | chr2 | GO:0007193 | Not Cancer Driver | No | 42 | 0.099 | 38 | 3 | 0.079 | 0 |
P2RY1 | P2RY1 | P47900 | P2Y purinoceptor 1 | chr3 | GO:0007193 | Not Cancer Driver | No | 60 | 0.161 | 16 | 1 | 0.062 | 0 |
P2RY12 | P2RY12 | Q9H244 | P2Y purinoceptor 12 | chr3 | GO:0007193 | Not Cancer Driver | No | 57 | 0.167 | 21 | 2 | 0.095 | 3 |
PALM | PALM | O75781 | Paralemmin-1 | chr19 | GO:0007193 | Not Cancer Driver | No | 50 | 0.129 | 381 | 50 | 0.131 | 0 |
PDE2A | PDE2A | O00408 | cGMP-dependent 3',5'-cyclic phosphodiesterase | chr11 | GO:0007193 | Not Cancer Driver | No | 137 | 0.146 | 99 | 7 | 0.071 | 0 |
PSAP | PSAP | P07602 | Prosaposin | chr10 | GO:0007193 | Not Cancer Driver | No | 59 | 0.113 | 28 | 2 | 0.071 | 8 |
PSAPL1 | PSAPL1 | Q6NUJ1 | Proactivator polypeptide-like 1 | chr4 | GO:0007193 | Not Cancer Driver | No | 62 | 0.119 | 7 | 1 | 0.143 | 0 |
PTGDR2 | PTGDR2 | Q9Y5Y4 | Prostaglandin D2 receptor 2 | chr11 | GO:0007193 | Not Cancer Driver | No | 23 | 0.058 | 39 | 0 | 0.0 | 0 |
RGS1 | RGS1 | Q08116 | Regulator of G-protein signaling 1 | chr1 | GO:0007193 | Not Cancer Driver | No | 50 | 0.239 | 45 | 12 | 0.267 | 0 |
RIC8A_ENST00000526104 | RIC8A | Q9NPQ8 | Synembryn-A | chr11 | GO:0007193 | Not Cancer Driver | No | 63 | 0.119 | 163 | 23 | 0.141 | 0 |
S1PR1 | S1PR1 | P21453 | Sphingosine 1-phosphate receptor 1 | chr1 | GO:0007193 | Not Cancer Driver | No | 86 | 0.225 | 29 | 6 | 0.207 | 0 |
S1PR3 | S1PR3 | Q99500 | Sphingosine 1-phosphate receptor 3 | chr9 | GO:0007193 | Not Cancer Driver | No | 69 | 0.183 | 28 | 4 | 0.143 | 0 |
SSTR2 | SSTR2 | P30874 | Somatostatin receptor type 2 | chr17 | GO:0007193 | Not Cancer Driver | No | 54 | 0.146 | 22 | 7 | 0.318 | 0 |