Total number of protein in "GO:0007188" GO term: 99
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ADCY2 | ADCY2 | Q08462 | Adenylate cyclase type 2 | chr5 | GO:0007188 | Not Cancer Driver | No | 303 | 0.278 | 95 | 24 | 0.253 | 0 |
| ADCY4_ENST00000554068 | ADCY4 | Q8NFM4 | Adenylate cyclase type 4 | chr14 | GO:0007188 | Not Cancer Driver | No | 137 | 0.127 | 94 | 23 | 0.245 | 0 |
| ADCY5 | ADCY5 | O95622 | Adenylate cyclase type 5 | chr3 | GO:0007188 | Not Cancer Driver | No | 234 | 0.186 | 268 | 23 | 0.086 | 2 |
| ADCY9 | ADCY9 | O60503 | Adenylate cyclase type 9 | chr16 | GO:0007188 | Not Cancer Driver | No | 195 | 0.144 | 271 | 42 | 0.155 | 0 |
| ADCYAP1R1_ENST00000304166 | ADCYAP1R1 | P41586 | Pituitary adenylate cyclase-activating polypeptide type I receptor | chr7 | GO:0007188 | Not Cancer Driver | No | 127 | 0.271 | 0 | 0 | 0.0 | 0 |
| ADORA2A | ADORA2A | P29274 | Adenosine receptor A2a | chr22 | GO:0007188 | Not Cancer Driver | No | 61 | 0.148 | 93 | 11 | 0.118 | 0 |
| ADRA1A_ENST00000380573 | ADRA1A | P35348 | Alpha-1A adrenergic receptor | chr8 | GO:0007188 | Not Cancer Driver | No | 130 | 0.279 | 40 | 8 | 0.2 | 0 |
| ADRA1B | ADRA1B | P35368 | Alpha-1B adrenergic receptor | chr5 | GO:0007188 | Not Cancer Driver | No | 53 | 0.102 | 132 | 1 | 0.008 | 0 |
| ADRA1D | ADRA1D | P25100 | Alpha-1D adrenergic receptor | chr20 | GO:0007188 | Not Cancer Driver | No | 62 | 0.108 | 189 | 19 | 0.101 | 0 |
| ADRA2A | ADRA2A | P08913 | Alpha-2A adrenergic receptor | chr10 | GO:0007188 | Not Cancer Driver | No | 67 | 0.144 | 161 | 10 | 0.062 | 0 |
| ADRA2B | ADRA2B | P18089 | Alpha-2B adrenergic receptor | chr2 | GO:0007188 | Not Cancer Driver | No | 73 | 0.162 | 136 | 20 | 0.147 | 0 |
| ADRA2C | ADRA2C | P18825 | Alpha-2C adrenergic receptor | chr4 | GO:0007188 | Not Cancer Driver | No | 47 | 0.102 | 107 | 0 | 0.0 | 0 |
| ADRB1 | ADRB1 | P08588 | Beta-1 adrenergic receptor | chr10 | GO:0007188 | Not Cancer Driver | No | 35 | 0.073 | 116 | 1 | 0.009 | 0 |
| ADRB2 | ADRB2 | P07550 | Beta-2 adrenergic receptor | chr5 | GO:0007188 | Not Cancer Driver | No | 52 | 0.126 | 35 | 4 | 0.114 | 0 |
| ADRB3 | ADRB3 | P13945 | Beta-3 adrenergic receptor | chr8 | GO:0007188 | Not Cancer Driver | No | 40 | 0.098 | 44 | 6 | 0.136 | 0 |
| AKAP13_ENST00000394518 | AKAP13 | Q12802 | A-kinase anchor protein 13 | chr15 | GO:0007188 | Not Cancer Driver | No | 359 | 0.128 | 2091 | 258 | 0.123 | 0 |
| AVPR1B | AVPR1B | P47901 | Vasopressin V1b receptor | chr1 | GO:0007188 | Not Cancer Driver | No | 83 | 0.196 | 51 | 5 | 0.098 | 0 |
| AVPR2_ENST00000337474 | AVPR2 | P30518 | Vasopressin V2 receptor | chrX | GO:0007188 | Not Cancer Driver | No | 58 | 0.156 | 56 | 7 | 0.125 | 84 |
| CACNA1D_ENST00000350061 | CACNA1D | Q01668 | Voltage-dependent L-type calcium channel subunit alpha-1D | chr3 | GO:0007188 | Census, Compendium | Yes | 342 | 0.158 | 736 | 126 | 0.171 | 2 |
| CALCRL | CALCRL | Q16602 | Calcitonin gene-related peptide type 1 receptor | chr2 | GO:0007188 | Not Cancer Driver | No | 122 | 0.265 | 8 | 4 | 0.5 | 0 |
| CALCR_ENST00000394441 | CALCR | P30988 | Calcitonin receptor | chr7 | GO:0007188 | Not Cancer Driver | No | 162 | 0.342 | 29 | 9 | 0.31 | 0 |
| CCR3_ENST00000357422 | CCR3 | P51677 | C-C chemokine receptor type 3 | chr3 | GO:0007188 | Not Cancer Driver | No | 84 | 0.237 | 0 | 0 | 0.0 | 0 |
| CHGA | CHGA | P10645 | Chromogranin-A | chr14 | GO:0007188 | Not Cancer Driver | No | 46 | 0.101 | 421 | 44 | 0.105 | 0 |
| CHRM1 | CHRM1 | P11229 | Muscarinic acetylcholine receptor M1 | chr11 | GO:0007188 | Not Cancer Driver | No | 63 | 0.137 | 131 | 24 | 0.183 | 0 |
| CHRM2_ENST00000320658 | CHRM2 | P08172 | Muscarinic acetylcholine receptor M2 | chr7 | GO:0007188 | Not Cancer Driver | No | 218 | 0.468 | 169 | 93 | 0.55 | 0 |
| CHRM3_ENST00000615928 | CHRM3 | P20309 | Muscarinic acetylcholine receptor M3 | chr1 | GO:0007188 | Not Cancer Driver | No | 182 | 0.308 | 136 | 42 | 0.309 | 0 |
| CHRM4 | CHRM4 | P08173 | Muscarinic acetylcholine receptor M4 | chr11 | GO:0007188 | Not Cancer Driver | No | 75 | 0.157 | 143 | 27 | 0.189 | 0 |
| CHRM5 | CHRM5 | P08912 | Muscarinic acetylcholine receptor M5 | chr15 | GO:0007188 | Not Cancer Driver | No | 74 | 0.139 | 155 | 20 | 0.129 | 0 |
| CNR1_ENST00000549890 | CNR1 | P21554 | Cannabinoid receptor 1 | chr6 | GO:0007188 | Not Cancer Driver | No | 129 | 0.273 | 9 | 1 | 0.111 | 0 |
| CRHR1 | CRHR1 | P34998 | Corticotropin-releasing factor receptor 1 | chr17 | GO:0007188 | Not Cancer Driver | No | 75 | 0.169 | 0 | 0 | 0.0 | 0 |
| CRHR2_ENST00000471646 | CRHR2 | Q13324 | Corticotropin-releasing factor receptor 2 | chr7 | GO:0007188 | Not Cancer Driver | No | 79 | 0.192 | 0 | 0 | 0.0 | 0 |
| DRD1 | DRD1 | P21728 | D(1A) dopamine receptor | chr5 | GO:0007188 | Not Cancer Driver | No | 73 | 0.164 | 30 | 4 | 0.133 | 0 |
| DRD2_ENST00000542968 | DRD2 | P14416 | D(2) dopamine receptor | chr11 | GO:0007188 | Not Cancer Driver | No | 127 | 0.287 | 124 | 45 | 0.363 | 0 |
| DRD3_ENST00000460779 | DRD3 | P35462 | D(3) dopamine receptor | chr3 | GO:0007188 | Not Cancer Driver | No | 88 | 0.22 | 45 | 17 | 0.378 | 0 |
| DRD4 | DRD4 | P21917 | D(4) dopamine receptor | chr11 | GO:0007188 | Not Cancer Driver | No | 26 | 0.062 | 109 | 0 | 0.0 | 0 |
| DRD5 | DRD5 | P21918 | D(1B) dopamine receptor | chr4 | GO:0007188 | Not Cancer Driver | No | 172 | 0.361 | 29 | 18 | 0.621 | 0 |
| FLNA | FLNA | P21333 | Filamin-A | chrX | GO:0007188 | Census | Yes | 416 | 0.157 | 1456 | 214 | 0.147 | 28 |
| FPR1_ENST00000304748 | FPR1 | P21462 | fMet-Leu-Phe receptor | chr19 | GO:0007188 | Not Cancer Driver | No | 99 | 0.283 | 18 | 3 | 0.167 | 0 |
| GALR2 | GALR2 | O43603 | Galanin receptor type 2 | chr17 | GO:0007188 | Not Cancer Driver | No | 40 | 0.103 | 0 | 0 | 0.0 | 0 |
| GALR3 | GALR3 | O60755 | Galanin receptor type 3 | chr22 | GO:0007188 | Not Cancer Driver | No | 15 | 0.041 | 53 | 0 | 0.0 | 0 |
| GCG | GCG | P01275 | Pro-glucagon | chr2 | GO:0007188 | Not Cancer Driver | No | 49 | 0.272 | 82 | 22 | 0.268 | 0 |
| GCGR | GCGR | P47871 | Glucagon receptor | chr17 | GO:0007188 | Not Cancer Driver | No | 16 | 0.034 | 56 | 2 | 0.036 | 4 |
| GHRHR | GHRHR | Q02643 | Growth hormone-releasing hormone receptor | chr7 | GO:0007188 | Not Cancer Driver | No | 41 | 0.097 | 3 | 0 | 0.0 | 5 |
| GIPR | GIPR | P48546 | Gastric inhibitory polypeptide receptor | chr19 | GO:0007188 | Not Cancer Driver | No | 45 | 0.097 | 41 | 0 | 0.0 | 0 |
| GLP1R | GLP1R | P43220 | Glucagon-like peptide 1 receptor | chr6 | GO:0007188 | Not Cancer Driver | No | 75 | 0.162 | 18 | 2 | 0.111 | 0 |
| GLP2R | GLP2R | O95838 | Glucagon-like peptide 2 receptor | chr17 | GO:0007188 | Not Cancer Driver | No | 124 | 0.224 | 63 | 14 | 0.222 | 0 |
| GNA11 | GNA11 | P29992 | Guanine nucleotide-binding protein subunit alpha-11 | chr19 | GO:0007188 | Census, Compendium | Yes | 48 | 0.134 | 10 | 0 | 0.0 | 5 |
| GNA12 | GNA12 | Q03113 | Guanine nucleotide-binding protein subunit alpha-12 | chr7 | GO:0007188 | Not Cancer Driver | No | 41 | 0.108 | 20 | 0 | 0.0 | 0 |
| GNA13 | GNA13 | Q14344 | Guanine nucleotide-binding protein subunit alpha-13 | chr17 | GO:0007188 | Compendium | Yes | 52 | 0.138 | 32 | 4 | 0.125 | 0 |
| GNA14 | GNA14 | O95837 | Guanine nucleotide-binding protein subunit alpha-14 | chr9 | GO:0007188 | Not Cancer Driver | No | 62 | 0.175 | 11 | 2 | 0.182 | 0 |
| GNA15 | GNA15 | P30679 | Guanine nucleotide-binding protein subunit alpha-15 | chr19 | GO:0007188 | Not Cancer Driver | No | 51 | 0.136 | 15 | 6 | 0.4 | 0 |
| GNAI1 | GNAI1 | P63096 | Guanine nucleotide-binding protein G(i) subunit alpha-1 | chr7 | GO:0007188 | Not Cancer Driver | No | 52 | 0.147 | 11 | 3 | 0.273 | 0 |
| GNAI2 | GNAI2 | P04899 | Guanine nucleotide-binding protein G(i) subunit alpha-2 | chr3 | GO:0007188 | Compendium | Yes | 50 | 0.141 | 24 | 0 | 0.0 | 0 |
| GNAI3 | GNAI3 | P08754 | Guanine nucleotide-binding protein G(i) subunit alpha-3 | chr1 | GO:0007188 | Not Cancer Driver | No | 42 | 0.119 | 11 | 0 | 0.0 | 1 |
| GNAL_ENST00000269162 | GNAL | P38405 | Guanine nucleotide-binding protein G(olf) subunit alpha | chr18 | GO:0007188 | Not Cancer Driver | No | 56 | 0.147 | 46 | 4 | 0.087 | 2 |
| GNAO1_ENST00000638705 | GNAO1 | P09471 | Guanine nucleotide-binding protein G(o) subunit alpha | chr16 | GO:0007188 | Not Cancer Driver | No | 54 | 0.153 | 10 | 0 | 0.0 | 15 |
| GNAQ | GNAQ | P50148 | Guanine nucleotide-binding protein G(q) subunit alpha | chr9 | GO:0007188 | Census, Compendium | Yes | 57 | 0.159 | 14 | 1 | 0.071 | 1 |
| GNAT1 | GNAT1 | P11488 | Guanine nucleotide-binding protein G(t) subunit alpha-1 | chr3 | GO:0007188 | Not Cancer Driver | No | 43 | 0.123 | 39 | 6 | 0.154 | 3 |
| GNAT2 | GNAT2 | P19087 | Guanine nucleotide-binding protein G(t) subunit alpha-2 | chr1 | GO:0007188 | Not Cancer Driver | No | 38 | 0.107 | 44 | 7 | 0.159 | 0 |
| GNAT3 | GNAT3 | A8MTJ3 | Guanine nucleotide-binding protein G(t) subunit alpha-3 | chr7 | GO:0007188 | Not Cancer Driver | No | 61 | 0.172 | 38 | 6 | 0.158 | 0 |
| GNAZ | GNAZ | P19086 | Guanine nucleotide-binding protein G(z) subunit alpha | chr22 | GO:0007188 | Not Cancer Driver | No | 84 | 0.237 | 30 | 13 | 0.433 | 0 |
| GNB1_ENST00000378609 | GNB1 | P62873 | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | chr1 | GO:0007188 | Not Cancer Driver | No | 45 | 0.132 | 24 | 2 | 0.083 | 16 |
| GNG2_ENST00000615906 | GNG2 | P59768 | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | chr14 | GO:0007188 | Not Cancer Driver | No | 17 | 0.239 | 12 | 3 | 0.25 | 0 |
| GPR101 | GPR101 | Q96P66 | Probable G-protein coupled receptor 101 | chrX | GO:0007188 | Not Cancer Driver | No | 131 | 0.258 | 177 | 48 | 0.271 | 1 |
| GRIK3 | GRIK3 | Q13003 | Glutamate receptor ionotropic, kainate 3 | chr1 | GO:0007188 | Not Cancer Driver | No | 256 | 0.279 | 38 | 9 | 0.237 | 0 |
| GRK5 | GRK5 | P34947 | G protein-coupled receptor kinase 5 | chr10 | GO:0007188 | Not Cancer Driver | No | 77 | 0.131 | 103 | 18 | 0.175 | 0 |
| GRM1_ENST00000282753 | GRM1 | Q13255 | Metabotropic glutamate receptor 1 | chr6 | GO:0007188 | Not Cancer Driver | No | 346 | 0.29 | 339 | 91 | 0.268 | 3 |
| GRM2 | GRM2 | Q14416 | Metabotropic glutamate receptor 2 | chr3 | GO:0007188 | Not Cancer Driver | No | 143 | 0.164 | 24 | 3 | 0.125 | 0 |
| GRM3 | GRM3 | Q14832 | Metabotropic glutamate receptor 3 | chr7 | GO:0007188 | Census | Yes | 323 | 0.367 | 8 | 3 | 0.375 | 0 |
| GRM4 | GRM4 | Q14833 | Metabotropic glutamate receptor 4 | chr6 | GO:0007188 | Not Cancer Driver | No | 187 | 0.205 | 74 | 22 | 0.297 | 0 |
| GRM5 | GRM5 | P41594 | Metabotropic glutamate receptor 5 | chr11 | GO:0007188 | Not Cancer Driver | No | 312 | 0.257 | 323 | 51 | 0.158 | 0 |
| GRM6_ENST00000517717 | GRM6 | O15303 | Metabotropic glutamate receptor 6 | chr5 | GO:0007188 | Not Cancer Driver | No | 200 | 0.228 | 113 | 23 | 0.204 | 6 |
| GRM7 | GRM7 | Q14831 | Metabotropic glutamate receptor 7 | chr3 | GO:0007188 | Not Cancer Driver | No | 316 | 0.345 | 91 | 31 | 0.341 | 1 |
| GRM8 | GRM8 | O00222 | Metabotropic glutamate receptor 8 | chr7 | GO:0007188 | Not Cancer Driver | No | 369 | 0.406 | 49 | 24 | 0.49 | 0 |
| HRH3 | HRH3 | Q9Y5N1 | Histamine H3 receptor | chr20 | GO:0007188 | Not Cancer Driver | No | 65 | 0.146 | 93 | 10 | 0.108 | 0 |
| HRH4 | HRH4 | Q9H3N8 | Histamine H4 receptor | chr18 | GO:0007188 | Not Cancer Driver | No | 72 | 0.185 | 1 | 1 | 1.0 | 0 |
| HTR1A | HTR1A | P08908 | 5-hydroxytryptamine receptor 1A | chr5 | GO:0007188 | Not Cancer Driver | No | 170 | 0.403 | 100 | 49 | 0.49 | 0 |
| HTR1B | HTR1B | P28222 | 5-hydroxytryptamine receptor 1B | chr6 | GO:0007188 | Not Cancer Driver | No | 91 | 0.233 | 33 | 15 | 0.455 | 0 |
| HTR1D | HTR1D | P28221 | 5-hydroxytryptamine receptor 1D | chr1 | GO:0007188 | Not Cancer Driver | No | 54 | 0.143 | 24 | 1 | 0.042 | 0 |
| HTR1E | HTR1E | P28566 | 5-hydroxytryptamine receptor 1E | chr6 | GO:0007188 | Not Cancer Driver | No | 133 | 0.364 | 18 | 5 | 0.278 | 0 |
| HTR1F | HTR1F | P30939 | 5-hydroxytryptamine receptor 1F | chr3 | GO:0007188 | Not Cancer Driver | No | 83 | 0.227 | 3 | 0 | 0.0 | 0 |
| HTR4_ENST00000377888 | HTR4 | Q13639 | 5-hydroxytryptamine receptor 4 | chr5 | GO:0007188 | Not Cancer Driver | No | 77 | 0.198 | 26 | 9 | 0.346 | 0 |
| HTR5A | HTR5A | P47898 | 5-hydroxytryptamine receptor 5A | chr7 | GO:0007188 | Not Cancer Driver | No | 174 | 0.487 | 6 | 1 | 0.167 | 0 |
| MC4R | MC4R | P32245 | Melanocortin receptor 4 | chr18 | GO:0007188 | Not Cancer Driver | No | 57 | 0.172 | 2 | 0 | 0.0 | 29 |
| OPRK1_ENST00000520287 | OPRK1 | P41145 | Kappa-type opioid receptor | chr8 | GO:0007188 | Not Cancer Driver | No | 117 | 0.308 | 18 | 5 | 0.278 | 0 |
| OPRM1_ENST00000330432 | OPRM1 | P35372 | Mu-type opioid receptor | chr6 | GO:0007188 | Not Cancer Driver | No | 107 | 0.268 | 58 | 27 | 0.466 | 0 |
| PDE4D | PDE4D | Q08499 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | chr5 | GO:0007188 | Not Cancer Driver | No | 86 | 0.106 | 464 | 54 | 0.116 | 12 |
| PLN | PLN | P26678 | Cardiac phospholamban | chr6 | GO:0007188 | Not Cancer Driver | No | 10 | 0.192 | 0 | 0 | 0.0 | 3 |
| PRKACB_ENST00000370689 | PRKACB | P22694 | cAMP-dependent protein kinase catalytic subunit beta | chr1 | GO:0007188 | Not Cancer Driver | No | 50 | 0.142 | 26 | 6 | 0.231 | 4 |
| PTGER1 | PTGER1 | P34995 | Prostaglandin E2 receptor EP1 subtype | chr19 | GO:0007188 | Not Cancer Driver | No | 7 | 0.017 | 26 | 1 | 0.038 | 0 |
| PTGER4 | PTGER4 | P35408 | Prostaglandin E2 receptor EP4 subtype | chr5 | GO:0007188 | Not Cancer Driver | No | 81 | 0.166 | 118 | 17 | 0.144 | 0 |
| PTH1R_ENST00000449590 | PTH1R | Q03431 | Parathyroid hormone/parathyroid hormone-related peptide receptor | chr3 | GO:0007188 | Not Cancer Driver | No | 86 | 0.145 | 124 | 25 | 0.202 | 5 |
| PTH2R | PTH2R | P49190 | Parathyroid hormone 2 receptor | chr2 | GO:0007188 | Not Cancer Driver | No | 123 | 0.224 | 49 | 17 | 0.347 | 0 |
| RAPGEF2 | RAPGEF2 | Q9Y4G8 | Rap guanine nucleotide exchange factor 2 | chr4 | GO:0007188 | Not Cancer Driver | No | 216 | 0.144 | 803 | 116 | 0.144 | 0 |
| SCTR | SCTR | P47872 | Secretin receptor | chr2 | GO:0007188 | Not Cancer Driver | No | 74 | 0.168 | 18 | 1 | 0.056 | 0 |
| SLC9A3R1 | SLC9A3R1 | O14745 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 | chr17 | GO:0007188 | Not Cancer Driver | No | 19 | 0.053 | 318 | 16 | 0.05 | 4 |
| VIPR1 | VIPR1 | P32241 | Vasoactive intestinal polypeptide receptor 1 | chr3 | GO:0007188 | Not Cancer Driver | No | 41 | 0.09 | 10 | 2 | 0.2 | 0 |
| VIPR2 | VIPR2 | P41587 | Vasoactive intestinal polypeptide receptor 2 | chr7 | GO:0007188 | Not Cancer Driver | No | 74 | 0.169 | 0 | 0 | 0.0 | 0 |
| WASF2 | WASF2 | Q9Y6W5 | Wiskott-Aldrich syndrome protein family member 2 | chr1 | GO:0007188 | Not Cancer Driver | No | 61 | 0.122 | 400 | 43 | 0.107 | 0 |