Total number of protein in "GO:0007169" GO term: 285
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABI1 | ABI1 | Q8IZP0 | Abl interactor 1 | chr10 | GO:0007169 | Census, Compendium | Yes | 55 | 0.108 | 360 | 39 | 0.108 | 0 |
| ABL1_ENST00000318560 | ABL1 | P00519 | Tyrosine-protein kinase ABL1 | chr9 | GO:0007169 | Census, Compendium | Yes | 139 | 0.123 | 604 | 73 | 0.121 | 2 |
| AHI1_ENST00000457866 | AHI1 | Q8N157 | Jouberin | chr6 | GO:0007169 | Not Cancer Driver | No | 120 | 0.1 | 500 | 56 | 0.112 | 6 |
| AKT1S1_ENST00000391834 | AKT1S1 | Q96B36 | Proline-rich AKT1 substrate 1 | chr19 | GO:0007169 | Not Cancer Driver | No | 23 | 0.09 | 256 | 23 | 0.09 | 0 |
| AKT1_ENST00000349310 | AKT1 | P31749 | RAC-alpha serine/threonine-protein kinase | chr14 | GO:0007169 | Census, Compendium | Yes | 108 | 0.225 | 158 | 24 | 0.152 | 4 |
| ALK | ALK | Q9UM73 | ALK tyrosine kinase receptor | chr2 | GO:0007169 | Census, Compendium | Yes | 303 | 0.187 | 575 | 114 | 0.198 | 16 |
| ANGPT1 | ANGPT1 | Q15389 | Angiopoietin-1 | chr8 | GO:0007169 | Not Cancer Driver | No | 130 | 0.261 | 131 | 24 | 0.183 | 1 |
| ANGPT2 | ANGPT2 | O15123 | Angiopoietin-2 | chr8 | GO:0007169 | Not Cancer Driver | No | 63 | 0.127 | 96 | 10 | 0.104 | 1 |
| ANGPTL1_ENST00000367629 | ANGPTL1 | O95841 | Angiopoietin-related protein 1 | chr1 | GO:0007169 | Not Cancer Driver | No | 68 | 0.138 | 95 | 13 | 0.137 | 0 |
| ANKS1A | ANKS1A | Q92625 | Ankyrin repeat and SAM domain-containing protein 1A | chr6 | GO:0007169 | Not Cancer Driver | No | 120 | 0.106 | 756 | 75 | 0.099 | 0 |
| ANKS1B | ANKS1B | Q7Z6G8 | Ankyrin repeat and sterile alpha motif domain-containing protein 1B | chr12 | GO:0007169 | Not Cancer Driver | No | 254 | 0.204 | 659 | 150 | 0.228 | 0 |
| ARHGEF28_ENST00000426542 | ARHGEF28 | Q8N1W1 | Rho guanine nucleotide exchange factor 28 | chr5 | GO:0007169 | Not Cancer Driver | No | 188 | 0.11 | 764 | 88 | 0.115 | 0 |
| ARHGEF7 | ARHGEF7 | Q14155 | Rho guanine nucleotide exchange factor 7 | chr13 | GO:0007169 | Not Cancer Driver | No | 106 | 0.132 | 301 | 39 | 0.13 | 0 |
| ARID5B | ARID5B | Q14865 | AT-rich interactive domain-containing protein 5B | chr10 | GO:0007169 | Not Cancer Driver | No | 162 | 0.136 | 769 | 95 | 0.124 | 0 |
| AXL | AXL | P30530 | Tyrosine-protein kinase receptor UFO | chr19 | GO:0007169 | Not Cancer Driver | No | 168 | 0.188 | 341 | 64 | 0.188 | 0 |
| BCAR1_ENST00000162330 | BCAR1 | P56945 | Breast cancer anti-estrogen resistance protein 1 | chr16 | GO:0007169 | Not Cancer Driver | No | 108 | 0.124 | 677 | 75 | 0.111 | 0 |
| BDKRB2 | BDKRB2 | P30411 | B2 bradykinin receptor | chr14 | GO:0007169 | Not Cancer Driver | No | 81 | 0.207 | 0 | 0 | 0.0 | 0 |
| BDNF_ENST00000439476 | BDNF | P23560 | Brain-derived neurotrophic factor | chr11 | GO:0007169 | Not Cancer Driver | No | 47 | 0.19 | 79 | 19 | 0.241 | 1 |
| BLK | BLK | P51451 | Tyrosine-protein kinase Blk | chr8 | GO:0007169 | Not Cancer Driver | No | 94 | 0.186 | 75 | 21 | 0.28 | 0 |
| BLNK | BLNK | Q8WV28 | B-cell linker protein | chr10 | GO:0007169 | Not Cancer Driver | No | 74 | 0.162 | 376 | 61 | 0.162 | 0 |
| C2CD5_ENST00000333957 | C2CD5 | Q86YS7 | C2 domain-containing protein 5 | chr12 | GO:0007169 | Not Cancer Driver | No | 136 | 0.136 | 250 | 40 | 0.16 | 0 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0007169 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CASS4 | CASS4 | Q9NQ75 | Cas scaffolding protein family member 4 | chr20 | GO:0007169 | Not Cancer Driver | No | 204 | 0.26 | 496 | 137 | 0.276 | 0 |
| CD3E | CD3E | P07766 | T-cell surface glycoprotein CD3 epsilon chain | chr11 | GO:0007169 | Not Cancer Driver | No | 28 | 0.135 | 72 | 12 | 0.167 | 0 |
| CD3EAP_ENST00000309424 | POLR1G | O15446 | DNA-directed RNA polymerase I subunit RPA34 | chr19 | GO:0007169 | Not Cancer Driver | No | 52 | 0.102 | 491 | 50 | 0.102 | 0 |
| CD4 | CD4 | P01730 | T-cell surface glycoprotein CD4 | chr12 | GO:0007169 | Not Cancer Driver | No | 69 | 0.151 | 56 | 11 | 0.196 | 0 |
| CD7 | CD7 | P09564 | T-cell antigen CD7 | chr17 | GO:0007169 | Not Cancer Driver | No | 36 | 0.15 | 74 | 7 | 0.095 | 0 |
| CD8A_ENST00000283635 | CD8A | P01732 | T-cell surface glycoprotein CD8 alpha chain | chr2 | GO:0007169 | Not Cancer Driver | No | 33 | 0.14 | 28 | 2 | 0.071 | 1 |
| CD8B_ENST00000390655 | CD8B | P10966 | T-cell surface glycoprotein CD8 beta chain | chr2 | GO:0007169 | Not Cancer Driver | No | 37 | 0.176 | 10 | 0 | 0.0 | 0 |
| CDK5R1 | CDK5R1 | Q15078 | Cyclin-dependent kinase 5 activator 1 | chr17 | GO:0007169 | Not Cancer Driver | No | 35 | 0.114 | 103 | 16 | 0.155 | 0 |
| CHN1 | CHN1 | P15882 | N-chimaerin | chr2 | GO:0007169 | Not Cancer Driver | No | 69 | 0.15 | 44 | 9 | 0.205 | 7 |
| CLEC14A | CLEC14A | Q86T13 | C-type lectin domain family 14 member A | chr14 | GO:0007169 | Not Cancer Driver | No | 147 | 0.3 | 182 | 60 | 0.33 | 0 |
| CLNK | CLNK | Q7Z7G1 | Cytokine-dependent hematopoietic cell linker | chr4 | GO:0007169 | Not Cancer Driver | No | 85 | 0.199 | 320 | 73 | 0.228 | 0 |
| CNKSR1 | CNKSR1 | Q969H4 | Connector enhancer of kinase suppressor of ras 1 | chr1 | GO:0007169 | Not Cancer Driver | No | 118 | 0.164 | 405 | 68 | 0.168 | 0 |
| COL1A1 | COL1A1 | P02452 | Collagen alpha-1(I) chain | chr17 | GO:0007169 | Census, Compendium | Yes | 247 | 0.169 | 1212 | 214 | 0.177 | 148 |
| COL4A1 | COL4A1 | P02462 | Collagen alpha-1(IV) chain | chr13 | GO:0007169 | Not Cancer Driver | No | 349 | 0.209 | 1457 | 310 | 0.213 | 32 |
| COL4A2 | COL4A2 | P08572 | Collagen alpha-2(IV) chain | chr13 | GO:0007169 | Not Cancer Driver | No | 264 | 0.154 | 1462 | 234 | 0.16 | 2 |
| COL4A3 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0007169 | Not Cancer Driver | No | 310 | 0.186 | 1433 | 277 | 0.193 | 13 |
| COL4A5_ENST00000361603 | COL4A5 | P29400 | Collagen alpha-5(IV) chain | chrX | GO:0007169 | Not Cancer Driver | No | 378 | 0.224 | 1459 | 327 | 0.224 | 144 |
| COL4A6_ENST00000372216 | COL4A6 | Q14031 | Collagen alpha-6(IV) chain | chrX | GO:0007169 | Not Cancer Driver | No | 286 | 0.169 | 1451 | 255 | 0.176 | 1 |
| CPNE3 | CPNE3 | O75131 | Copine-3 | chr8 | GO:0007169 | Not Cancer Driver | No | 79 | 0.147 | 33 | 5 | 0.152 | 0 |
| CRIM1 | CRIM1 | Q9NZV1 | Cysteine-rich motor neuron 1 protein | chr2 | GO:0007169 | Not Cancer Driver | No | 133 | 0.128 | 35 | 4 | 0.114 | 0 |
| CRK | CRK | P46108 | Adapter molecule crk | chr17 | GO:0007169 | Not Cancer Driver | No | 30 | 0.099 | 197 | 23 | 0.117 | 0 |
| CSF1R | CSF1R | P07333 | Macrophage colony-stimulating factor 1 receptor | chr5 | GO:0007169 | Census | Yes | 133 | 0.137 | 124 | 17 | 0.137 | 20 |
| CSF1_ENST00000369802 | CSF1 | P09603 | Macrophage colony-stimulating factor 1 | chr1 | GO:0007169 | Not Cancer Driver | No | 69 | 0.125 | 339 | 46 | 0.136 | 0 |
| CSH1 | CSH1 | P0DML2 | Chorionic somatomammotropin hormone 1 | chr17 | GO:0007169 | Not Cancer Driver | No | 33 | 0.152 | 23 | 2 | 0.087 | 0 |
| CSH2 | CSH2 | P0DML3 | Chorionic somatomammotropin hormone 2 | chr17 | GO:0007169 | Not Cancer Driver | No | 53 | 0.244 | 23 | 3 | 0.13 | 0 |
| CSHL1 | CSHL1 | Q14406 | Chorionic somatomammotropin hormone-like 1 | chr17 | GO:0007169 | Not Cancer Driver | No | 63 | 0.284 | 18 | 5 | 0.278 | 0 |
| CSPG4 | CSPG4 | Q6UVK1 | Chondroitin sulfate proteoglycan 4 | chr15 | GO:0007169 | Not Cancer Driver | No | 259 | 0.112 | 838 | 85 | 0.101 | 0 |
| CSRNP1 | CSRNP1 | Q96S65 | Cysteine/serine-rich nuclear protein 1 | chr3 | GO:0007169 | Not Cancer Driver | No | 71 | 0.121 | 312 | 33 | 0.106 | 0 |
| CUL5 | CUL5 | Q93034 | Cullin-5 | chr11 | GO:0007169 | Not Cancer Driver | No | 97 | 0.124 | 5 | 1 | 0.2 | 0 |
| DAB2IP_ENST00000408936 | DAB2IP | Q5VWQ8 | Disabled homolog 2-interacting protein | chr9 | GO:0007169 | Not Cancer Driver | No | 131 | 0.11 | 681 | 68 | 0.1 | 0 |
| DDIT4 | DDIT4 | Q9NX09 | DNA damage-inducible transcript 4 protein | chr10 | GO:0007169 | Not Cancer Driver | No | 20 | 0.086 | 87 | 9 | 0.103 | 0 |
| DDR1_ENST00000324771 | DDR1 | Q08345 | Epithelial discoidin domain-containing receptor 1 | chr6 | GO:0007169 | Not Cancer Driver | No | 123 | 0.135 | 253 | 49 | 0.194 | 0 |
| DDR2 | DDR2 | Q16832 | Discoidin domain-containing receptor 2 | chr1 | GO:0007169 | Census | Yes | 192 | 0.225 | 118 | 34 | 0.288 | 7 |
| DOK1 | DOK1 | Q99704 | Docking protein 1 | chr2 | GO:0007169 | Not Cancer Driver | No | 50 | 0.104 | 294 | 31 | 0.105 | 0 |
| DOK2 | DOK2 | O60496 | Docking protein 2 | chr8 | GO:0007169 | Not Cancer Driver | No | 58 | 0.141 | 254 | 31 | 0.122 | 0 |
| DOK3 | DOK3 | Q7L591 | Docking protein 3 | chr5 | GO:0007169 | Not Cancer Driver | No | 61 | 0.123 | 281 | 37 | 0.132 | 0 |
| DOK4_ENST00000340099 | DOK4 | Q8TEW6 | Docking protein 4 | chr16 | GO:0007169 | Not Cancer Driver | No | 42 | 0.129 | 45 | 3 | 0.067 | 0 |
| DOK5 | DOK5 | Q9P104 | Docking protein 5 | chr20 | GO:0007169 | Not Cancer Driver | No | 87 | 0.284 | 15 | 7 | 0.467 | 0 |
| DOK6 | DOK6 | Q6PKX4 | Docking protein 6 | chr18 | GO:0007169 | Not Cancer Driver | No | 98 | 0.296 | 48 | 11 | 0.229 | 0 |
| EFNA1 | EFNA1 | P20827 | Ephrin-A1 | chr1 | GO:0007169 | Not Cancer Driver | No | 29 | 0.141 | 46 | 5 | 0.109 | 0 |
| EFNA2 | EFNA2 | O43921 | Ephrin-A2 | chr19 | GO:0007169 | Not Cancer Driver | No | 16 | 0.075 | 13 | 2 | 0.154 | 0 |
| EFNA3 | EFNA3 | P52797 | Ephrin-A3 | chr1 | GO:0007169 | Not Cancer Driver | No | 24 | 0.101 | 31 | 11 | 0.355 | 0 |
| EFNA4_ENST00000368409 | EFNA4 | P52798 | Ephrin-A4 | chr1 | GO:0007169 | Not Cancer Driver | No | 28 | 0.139 | 17 | 3 | 0.176 | 0 |
| EFNA5 | EFNA5 | P52803 | Ephrin-A5 | chr5 | GO:0007169 | Not Cancer Driver | No | 34 | 0.149 | 25 | 6 | 0.24 | 0 |
| EFNB1 | EFNB1 | P98172 | Ephrin-B1 | chrX | GO:0007169 | Not Cancer Driver | No | 46 | 0.133 | 126 | 14 | 0.111 | 19 |
| EFNB2_ENST00000245323 | EFNB2 | P52799 | Ephrin-B2 | chr13 | GO:0007169 | Not Cancer Driver | No | 42 | 0.126 | 97 | 15 | 0.155 | 0 |
| EFNB3 | EFNB3 | Q15768 | Ephrin-B3 | chr17 | GO:0007169 | Not Cancer Driver | No | 45 | 0.132 | 183 | 22 | 0.12 | 0 |
| EFS | EFS | O43281 | Embryonal Fyn-associated substrate | chr14 | GO:0007169 | Not Cancer Driver | No | 74 | 0.132 | 414 | 57 | 0.138 | 0 |
| EGF | EGF | P01133 | Pro-epidermal growth factor | chr4 | GO:0007169 | Not Cancer Driver | No | 184 | 0.152 | 191 | 25 | 0.131 | 1 |
| EGFR | EGFR | P00533 | Epidermal growth factor receptor | chr7 | GO:0007169 | Census, Compendium | Yes | 444 | 0.367 | 223 | 35 | 0.157 | 1 |
| EIF2AK3 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0007169 | Not Cancer Driver | No | 149 | 0.134 | 410 | 51 | 0.124 | 1 |
| EPHA1 | EPHA1 | P21709 | Ephrin type-A receptor 1 | chr7 | GO:0007169 | Not Cancer Driver | No | 147 | 0.151 | 211 | 38 | 0.18 | 0 |
| EPHA10 | EPHA10 | Q5JZY3 | Ephrin type-A receptor 10 | chr1 | GO:0007169 | Not Cancer Driver | No | 171 | 0.17 | 225 | 41 | 0.182 | 0 |
| EPHA2 | EPHA2 | P29317 | Ephrin type-A receptor 2 | chr1 | GO:0007169 | Compendium | Yes | 171 | 0.175 | 187 | 39 | 0.209 | 3 |
| EPHA3 | EPHA3 | P29320 | Ephrin type-A receptor 3 | chr3 | GO:0007169 | Census, Compendium | Yes | 346 | 0.352 | 74 | 28 | 0.378 | 0 |
| EPHA4_ENST00000409938 | EPHA4 | P54764 | Ephrin type-A receptor 4 | chr2 | GO:0007169 | Not Cancer Driver | No | 182 | 0.185 | 140 | 24 | 0.171 | 0 |
| EPHA5_ENST00000273854 | EPHA5 | P54756 | Ephrin type-A receptor 5 | chr4 | GO:0007169 | Not Cancer Driver | No | 341 | 0.329 | 83 | 39 | 0.47 | 0 |
| EPHA7 | EPHA7 | Q15375 | Ephrin type-A receptor 7 | chr6 | GO:0007169 | Census, Compendium | Yes | 280 | 0.281 | 71 | 15 | 0.211 | 0 |
| EPHA8 | EPHA8 | P29322 | Ephrin type-A receptor 8 | chr1 | GO:0007169 | Not Cancer Driver | No | 197 | 0.196 | 121 | 17 | 0.14 | 0 |
| EPHB1 | EPHB1 | P54762 | Ephrin type-B receptor 1 | chr3 | GO:0007169 | Not Cancer Driver | No | 316 | 0.321 | 67 | 17 | 0.254 | 0 |
| EPHB2 | EPHB2 | P29323 | Ephrin type-B receptor 2 | chr1 | GO:0007169 | Not Cancer Driver | No | 186 | 0.176 | 119 | 17 | 0.143 | 7 |
| EPHB3 | EPHB3 | P54753 | Ephrin type-B receptor 3 | chr3 | GO:0007169 | Not Cancer Driver | No | 155 | 0.155 | 137 | 16 | 0.117 | 0 |
| EPHB4 | EPHB4 | P54760 | Ephrin type-B receptor 4 | chr7 | GO:0007169 | Not Cancer Driver | No | 125 | 0.127 | 184 | 19 | 0.103 | 11 |
| EPHB6_ENST00000422643 | EPHB6 | O15197 | Ephrin type-B receptor 6 | chr7 | GO:0007169 | Not Cancer Driver | No | 227 | 0.222 | 246 | 45 | 0.183 | 0 |
| ERBB2 | ERBB2 | P04626 | Receptor tyrosine-protein kinase erbB-2 | chr17 | GO:0007169 | Census, Compendium | Yes | 275 | 0.219 | 314 | 41 | 0.131 | 1 |
| ERBB3 | ERBB3 | P21860 | Receptor tyrosine-protein kinase erbB-3 | chr12 | GO:0007169 | Census, Compendium | Yes | 298 | 0.222 | 396 | 70 | 0.177 | 3 |
| ERBB4 | ERBB4 | Q15303 | Receptor tyrosine-protein kinase erbB-4 | chr2 | GO:0007169 | Census, Compendium | Yes | 428 | 0.327 | 323 | 116 | 0.359 | 2 |
| FER | FER | P16591 | Tyrosine-protein kinase Fer | chr5 | GO:0007169 | Not Cancer Driver | No | 114 | 0.139 | 145 | 21 | 0.145 | 0 |
| FES | FES | P07332 | Tyrosine-protein kinase Fes/Fps | chr15 | GO:0007169 | Census | Yes | 103 | 0.125 | 245 | 34 | 0.139 | 0 |
| FGF10 | FGF10 | O15520 | Fibroblast growth factor 10 | chr5 | GO:0007169 | Not Cancer Driver | No | 56 | 0.269 | 34 | 11 | 0.324 | 2 |
| FGF21 | FGF21 | Q9NSA1 | Fibroblast growth factor 21 | chr19 | GO:0007169 | Not Cancer Driver | No | 37 | 0.177 | 109 | 24 | 0.22 | 0 |
| FGF23 | FGF23 | Q9GZV9 | Fibroblast growth factor 23 | chr12 | GO:0007169 | Not Cancer Driver | No | 84 | 0.335 | 97 | 51 | 0.526 | 7 |
| FGFR1_ENST00000447712 | FGFR1 | P11362 | Fibroblast growth factor receptor 1 | chr8 | GO:0007169 | Census, Compendium | Yes | 152 | 0.185 | 230 | 43 | 0.187 | 74 |
| FGFR2_ENST00000358487 | FGFR2 | P21802 | Fibroblast growth factor receptor 2 | chr10 | GO:0007169 | Census, Compendium | Yes | 238 | 0.29 | 228 | 44 | 0.193 | 72 |
| FGFR3_ENST00000440486 | FGFR3 | P22607 | Fibroblast growth factor receptor 3 | chr4 | GO:0007169 | Census, Compendium | Yes | 173 | 0.215 | 241 | 26 | 0.108 | 37 |
| FGFR4 | FGFR4 | P22455 | Fibroblast growth factor receptor 4 | chr5 | GO:0007169 | Census, Compendium | Yes | 113 | 0.141 | 162 | 28 | 0.173 | 0 |
| FGR_ENST00000374004 | FGR | P09769 | Tyrosine-protein kinase Fgr | chr1 | GO:0007169 | Not Cancer Driver | No | 85 | 0.161 | 52 | 8 | 0.154 | 0 |
| FLT1 | FLT1 | P17948 | Vascular endothelial growth factor receptor 1 | chr13 | GO:0007169 | Not Cancer Driver | No | 299 | 0.223 | 103 | 20 | 0.194 | 0 |
| FLT3 | FLT3 | P36888 | Receptor-type tyrosine-protein kinase FLT3 | chr13 | GO:0007169 | Census, Compendium | Yes | 200 | 0.201 | 64 | 27 | 0.422 | 0 |
| FLT4 | FLT4 | P35916 | Vascular endothelial growth factor receptor 3 | chr5 | GO:0007169 | Census, Compendium | Yes | 253 | 0.186 | 259 | 41 | 0.158 | 13 |
| FOXC1_ENST00000645831 | FOXC1 | Q12948 | Forkhead box protein C1 | chr6 | GO:0007169 | Not Cancer Driver | No | 33 | 0.06 | 411 | 24 | 0.058 | 32 |
| FOXC2 | FOXC2 | Q99958 | Forkhead box protein C2 | chr16 | GO:0007169 | Not Cancer Driver | No | 63 | 0.126 | 369 | 33 | 0.089 | 1 |
| FRK | FRK | P42685 | Tyrosine-protein kinase FRK | chr6 | GO:0007169 | Not Cancer Driver | No | 87 | 0.172 | 18 | 2 | 0.111 | 0 |
| FRS2 | FRS2 | Q8WU20 | Fibroblast growth factor receptor substrate 2 | chr12 | GO:0007169 | Not Cancer Driver | No | 69 | 0.136 | 415 | 58 | 0.14 | 0 |
| FRS3_ENST00000259748 | FRS3 | O43559 | Fibroblast growth factor receptor substrate 3 | chr6 | GO:0007169 | Not Cancer Driver | No | 77 | 0.157 | 388 | 58 | 0.149 | 0 |
| FYN | FYN | P06241 | Tyrosine-protein kinase Fyn | chr6 | GO:0007169 | Not Cancer Driver | No | 92 | 0.171 | 70 | 13 | 0.186 | 0 |
| GAB1_ENST00000262994 | GAB1 | Q13480 | GRB2-associated-binding protein 1 | chr4 | GO:0007169 | Not Cancer Driver | No | 79 | 0.114 | 570 | 68 | 0.119 | 1 |
| GAB2 | GAB2 | Q9UQC2 | GRB2-associated-binding protein 2 | chr11 | GO:0007169 | Not Cancer Driver | No | 85 | 0.126 | 537 | 73 | 0.136 | 0 |
| GDF15 | GDF15 | Q99988 | Growth/differentiation factor 15 | chr19 | GO:0007169 | Not Cancer Driver | No | 39 | 0.127 | 143 | 20 | 0.14 | 0 |
| GFRA1 | GFRA1 | P56159 | GDNF family receptor alpha-1 | chr10 | GO:0007169 | Not Cancer Driver | No | 120 | 0.258 | 43 | 12 | 0.279 | 0 |
| GFRA2 | GFRA2 | O00451 | GDNF family receptor alpha-2 | chr8 | GO:0007169 | Not Cancer Driver | No | 60 | 0.129 | 71 | 25 | 0.352 | 0 |
| GFRA3 | GFRA3 | O60609 | GDNF family receptor alpha-3 | chr5 | GO:0007169 | Not Cancer Driver | No | 50 | 0.125 | 40 | 4 | 0.1 | 0 |
| GFRA4 | GFRA4 | Q9GZZ7 | GDNF family receptor alpha-4 | chr20 | GO:0007169 | Not Cancer Driver | No | 13 | 0.043 | 85 | 4 | 0.047 | 0 |
| GFRAL | GFRAL | Q6UXV0 | GDNF family receptor alpha-like | chr6 | GO:0007169 | Not Cancer Driver | No | 176 | 0.447 | 5 | 2 | 0.4 | 0 |
| GH1 | GH1 | P01241 | Somatotropin | chr17 | GO:0007169 | Not Cancer Driver | No | 54 | 0.249 | 24 | 9 | 0.375 | 15 |
| GH2_ENST00000423893 | GH2 | P01242 | Growth hormone variant | chr17 | GO:0007169 | Not Cancer Driver | No | 55 | 0.253 | 12 | 9 | 0.75 | 0 |
| GHR_ENST00000612382 | GHR | P10912 | Growth hormone receptor | chr5 | GO:0007169 | Not Cancer Driver | No | 173 | 0.271 | 229 | 66 | 0.288 | 19 |
| GIGYF1_ENST00000646601 | GIGYF1 | O75420 | GRB10-interacting GYF protein 1 | chr7 | GO:0007169 | Not Cancer Driver | No | 138 | 0.133 | 857 | 115 | 0.134 | 0 |
| GIGYF2_ENST00000409547 | GIGYF2 | Q6Y7W6 | GRB10-interacting GYF protein 2 | chr2 | GO:0007169 | Not Cancer Driver | No | 176 | 0.135 | 1096 | 158 | 0.144 | 6 |
| GIT1_ENST00000225394 | GIT1 | Q9Y2X7 | ARF GTPase-activating protein GIT1 | chr17 | GO:0007169 | Not Cancer Driver | No | 67 | 0.088 | 434 | 42 | 0.097 | 0 |
| GRB10_ENST00000401949 | GRB10 | Q13322 | Growth factor receptor-bound protein 10 | chr7 | GO:0007169 | Not Cancer Driver | No | 94 | 0.158 | 220 | 38 | 0.173 | 0 |
| HAP1_ENST00000310778 | HAP1 | P54257 | Huntingtin-associated protein 1 | chr17 | GO:0007169 | Not Cancer Driver | No | 97 | 0.145 | 454 | 60 | 0.132 | 0 |
| HCK_ENST00000534862 | HCK | P08631 | Tyrosine-protein kinase HCK | chr20 | GO:0007169 | Not Cancer Driver | No | 112 | 0.213 | 124 | 25 | 0.202 | 0 |
| HGF_ENST00000644543 | HGF | P14210 | Hepatocyte growth factor | chr7 | GO:0007169 | Compendium | Yes | 233 | 0.32 | 43 | 16 | 0.372 | 0 |
| HSPB1 | HSPB1 | P04792 | Heat shock protein beta-1 | chr7 | GO:0007169 | Not Cancer Driver | No | 10 | 0.049 | 118 | 8 | 0.068 | 20 |
| IGF1R | IGF1R | P08069 | Insulin-like growth factor 1 receptor | chr15 | GO:0007169 | Not Cancer Driver | No | 183 | 0.134 | 265 | 37 | 0.14 | 6 |
| IGF1_ENST00000307046 | IGF1 | P05019 | Insulin-like growth factor I | chr12 | GO:0007169 | Not Cancer Driver | No | 45 | 0.231 | 87 | 23 | 0.264 | 0 |
| IGF2R | IGF2R | P11717 | Cation-independent mannose-6-phosphate receptor | chr6 | GO:0007169 | Not Cancer Driver | No | 318 | 0.128 | 255 | 20 | 0.078 | 0 |
| IGF2_ENST00000641326 | IGF2 | P01344 | Insulin-like growth factor II | chr11 | GO:0007169 | Not Cancer Driver | No | 39 | 0.217 | 44 | 12 | 0.273 | 0 |
| IL31RA_ENST00000297015 | IL31RA | Q8NI17 | Interleukin-31 receptor subunit alpha | chr5 | GO:0007169 | Not Cancer Driver | No | 117 | 0.16 | 163 | 30 | 0.184 | 1 |
| INSR | INSR | P06213 | Insulin receptor | chr19 | GO:0007169 | Not Cancer Driver | No | 190 | 0.137 | 280 | 57 | 0.204 | 64 |
| INSRR | INSRR | P14616 | Insulin receptor-related protein | chr1 | GO:0007169 | Not Cancer Driver | No | 262 | 0.202 | 228 | 37 | 0.162 | 0 |
| IQGAP1 | IQGAP1 | P46940 | Ras GTPase-activating-like protein IQGAP1 | chr15 | GO:0007169 | Not Cancer Driver | No | 183 | 0.11 | 351 | 35 | 0.1 | 0 |
| IRS1 | IRS1 | P35568 | Insulin receptor substrate 1 | chr2 | GO:0007169 | Not Cancer Driver | No | 161 | 0.13 | 1072 | 133 | 0.124 | 2 |
| JAK1 | JAK1 | P23458 | Tyrosine-protein kinase JAK1 | chr1 | GO:0007169 | Census, Compendium | Yes | 147 | 0.127 | 120 | 7 | 0.058 | 2 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0007169 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| JAK3 | JAK3 | P52333 | Tyrosine-protein kinase JAK3 | chr19 | GO:0007169 | Census, Compendium | Yes | 167 | 0.149 | 63 | 10 | 0.159 | 7 |
| KALRN_ENST00000360013 | KALRN | O60229 | Kalirin | chr3 | GO:0007169 | Not Cancer Driver | No | 544 | 0.182 | 732 | 128 | 0.175 | 0 |
| KDR | KDR | P35968 | Vascular endothelial growth factor receptor 2 | chr4 | GO:0007169 | Census, Compendium | Yes | 357 | 0.263 | 275 | 55 | 0.2 | 2 |
| KIT | KIT | P10721 | Mast/stem cell growth factor receptor Kit | chr4 | GO:0007169 | Census, Compendium | Yes | 226 | 0.232 | 83 | 33 | 0.398 | 21 |
| KL | KL | Q9UEF7 | Klotho | chr13 | GO:0007169 | Not Cancer Driver | No | 175 | 0.173 | 104 | 5 | 0.048 | 1 |
| KLB | KLB | Q86Z14 | Beta-klotho | chr4 | GO:0007169 | Not Cancer Driver | No | 139 | 0.133 | 6 | 1 | 0.167 | 0 |
| LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0007169 | Census | Yes | 86 | 0.169 | 94 | 13 | 0.138 | 1 |
| LCP2 | LCP2 | Q13094 | Lymphocyte cytosolic protein 2 | chr5 | GO:0007169 | Not Cancer Driver | No | 107 | 0.201 | 390 | 80 | 0.205 | 0 |
| LMTK2 | LMTK2 | Q8IWU2 | Serine/threonine-protein kinase LMTK2 | chr7 | GO:0007169 | Not Cancer Driver | No | 211 | 0.14 | 1018 | 141 | 0.139 | 0 |
| LOX | LOX | P28300 | Protein-lysine 6-oxidase | chr5 | GO:0007169 | Compendium | Yes | 44 | 0.106 | 172 | 11 | 0.064 | 4 |
| LTK | LTK | P29376 | Leukocyte tyrosine kinase receptor | chr15 | GO:0007169 | Not Cancer Driver | No | 103 | 0.119 | 301 | 30 | 0.1 | 0 |
| LYN | LYN | P07948 | Tyrosine-protein kinase Lyn | chr8 | GO:0007169 | Census | Yes | 95 | 0.186 | 84 | 12 | 0.143 | 0 |
| MAPK14_ENST00000229794 | MAPK14 | Q16539 | Mitogen-activated protein kinase 14 | chr6 | GO:0007169 | Not Cancer Driver | No | 39 | 0.108 | 25 | 1 | 0.04 | 0 |
| MAPKAPK2 | MAPKAPK2 | P49137 | MAP kinase-activated protein kinase 2 | chr1 | GO:0007169 | Not Cancer Driver | No | 43 | 0.107 | 92 | 5 | 0.054 | 0 |
| MAPKAPK3 | MAPKAPK3 | Q16644 | MAP kinase-activated protein kinase 3 | chr3 | GO:0007169 | Not Cancer Driver | No | 35 | 0.092 | 117 | 12 | 0.103 | 1 |
| MERTK_ENST00000421804 | MERTK | Q12866 | Tyrosine-protein kinase Mer | chr2 | GO:0007169 | Not Cancer Driver | No | 175 | 0.175 | 159 | 31 | 0.195 | 3 |
| MET_ENST00000397752 | MET | P08581 | Hepatocyte growth factor receptor | chr7 | GO:0007169 | Census, Compendium | Yes | 226 | 0.163 | 62 | 15 | 0.242 | 19 |
| MMP2 | MMP2 | P08253 | 72 kDa type IV collagenase | chr16 | GO:0007169 | Not Cancer Driver | No | 123 | 0.186 | 29 | 6 | 0.207 | 2 |
| MMP9 | MMP9 | P14780 | Matrix metalloproteinase-9 | chr20 | GO:0007169 | Not Cancer Driver | No | 129 | 0.182 | 124 | 26 | 0.21 | 0 |
| MPZL1 | MPZL1 | O95297 | Myelin protein zero-like protein 1 | chr1 | GO:0007169 | Not Cancer Driver | No | 36 | 0.134 | 56 | 7 | 0.125 | 0 |
| MST1R | MST1R | Q04912 | Macrophage-stimulating protein receptor | chr3 | GO:0007169 | Not Cancer Driver | No | 178 | 0.127 | 182 | 27 | 0.148 | 1 |
| MTSS1_ENST00000518547 | MTSS1 | O43312 | Protein MTSS 1 | chr8 | GO:0007169 | Not Cancer Driver | No | 107 | 0.142 | 584 | 86 | 0.147 | 0 |
| MUC20 | MUC20 | Q8N307 | Mucin-20 | chr3 | GO:0007169 | Not Cancer Driver | No | 107 | 0.151 | 680 | 100 | 0.147 | 0 |
| MUSK | MUSK | O15146 | Muscle, skeletal receptor tyrosine-protein kinase | chr9 | GO:0007169 | Not Cancer Driver | No | 188 | 0.216 | 35 | 7 | 0.2 | 7 |
| MYO1C | MYO1C | O00159 | Unconventional myosin-Ic | chr17 | GO:0007169 | Not Cancer Driver | No | 110 | 0.103 | 66 | 11 | 0.167 | 0 |
| MYO1E | MYO1E | Q12965 | Unconventional myosin-Ie | chr15 | GO:0007169 | Not Cancer Driver | No | 137 | 0.124 | 229 | 14 | 0.061 | 1 |
| MYOC | MYOC | Q99972 | Myocilin | chr1 | GO:0007169 | Not Cancer Driver | No | 92 | 0.183 | 196 | 43 | 0.219 | 58 |
| NCK1_ENST00000288986 | NCK1 | P16333 | Cytoplasmic protein NCK1 | chr3 | GO:0007169 | Not Cancer Driver | No | 48 | 0.127 | 111 | 17 | 0.153 | 0 |
| NCK2_ENST00000393349 | NCK2 | O43639 | Cytoplasmic protein NCK2 | chr2 | GO:0007169 | Not Cancer Driver | No | 89 | 0.234 | 88 | 19 | 0.216 | 0 |
| NDN | NDN | Q99608 | Necdin | chr15 | GO:0007169 | Not Cancer Driver | No | 123 | 0.383 | 117 | 42 | 0.359 | 0 |
| NEDD9 | NEDD9 | Q14511 | Enhancer of filamentation 1 | chr6 | GO:0007169 | Not Cancer Driver | No | 106 | 0.127 | 516 | 72 | 0.14 | 0 |
| NFATC4_ENST00000250373 | NFATC4 | Q14934 | Nuclear factor of activated T-cells, cytoplasmic 4 | chr14 | GO:0007169 | Not Cancer Driver | No | 155 | 0.172 | 685 | 120 | 0.175 | 0 |
| NGEF | NGEF | Q8N5V2 | Ephexin-1 | chr2 | GO:0007169 | Not Cancer Driver | No | 125 | 0.176 | 296 | 34 | 0.115 | 0 |
| NGF | NGF | P01138 | Beta-nerve growth factor | chr1 | GO:0007169 | Not Cancer Driver | No | 66 | 0.274 | 93 | 25 | 0.269 | 1 |
| NOG | NOG | Q13253 | Noggin | chr17 | GO:0007169 | Not Cancer Driver | No | 22 | 0.095 | 86 | 9 | 0.105 | 20 |
| NR4A3_ENST00000395097 | NR4A3 | Q92570 | Nuclear receptor subfamily 4 group A member 3 | chr9 | GO:0007169 | Census | Yes | 83 | 0.133 | 298 | 37 | 0.124 | 0 |
| NRG1_ENST00000405005 | NRG1 | Q02297 | Pro-neuregulin-1, membrane-bound isoform | chr8 | GO:0007169 | Census, Compendium | Yes | 159 | 0.248 | 528 | 132 | 0.25 | 0 |
| NRP1 | NRP1 | O14786 | Neuropilin-1 | chr10 | GO:0007169 | Compendium | Yes | 146 | 0.158 | 211 | 31 | 0.147 | 0 |
| NRP2 | NRP2 | O60462 | Neuropilin-2 | chr2 | GO:0007169 | Not Cancer Driver | No | 161 | 0.173 | 207 | 45 | 0.217 | 0 |
| NRTN | NRTN | Q99748 | Neurturin | chr19 | GO:0007169 | Not Cancer Driver | No | 7 | 0.036 | 26 | 0 | 0.0 | 0 |
| NTF3_ENST00000331010 | NTF3 | P20783 | Neurotrophin-3 | chr12 | GO:0007169 | Not Cancer Driver | No | 52 | 0.202 | 99 | 21 | 0.212 | 0 |
| NTF4 | NTF4 | P34130 | Neurotrophin-4 | chr19 | GO:0007169 | Not Cancer Driver | No | 21 | 0.1 | 56 | 4 | 0.071 | 0 |
| NTRK1 | NTRK1 | P04629 | High affinity nerve growth factor receptor | chr1 | GO:0007169 | Census, Compendium | Yes | 168 | 0.211 | 57 | 8 | 0.14 | 25 |
| NTRK2_ENST00000323115 | NTRK2 | Q16620 | BDNF/NT-3 growth factors receptor | chr9 | GO:0007169 | Not Cancer Driver | No | 155 | 0.189 | 117 | 18 | 0.154 | 1 |
| NTRK3_ENST00000629765 | NTRK3 | Q16288 | NT-3 growth factor receptor | chr15 | GO:0007169 | Census, Compendium | Yes | 249 | 0.297 | 57 | 21 | 0.368 | 0 |
| NUS1 | NUS1 | Q96E22 | Dehydrodolichyl diphosphate synthase complex subunit NUS1 | chr6 | GO:0007169 | Not Cancer Driver | No | 21 | 0.072 | 13 | 0 | 0.0 | 1 |
| OTOL1 | OTOL1 | A6NHN0 | Otolin-1 | chr3 | GO:0007169 | Not Cancer Driver | No | 121 | 0.254 | 321 | 70 | 0.218 | 0 |
| PAK1_ENST00000356341 | PAK1 | Q13153 | Serine/threonine-protein kinase PAK 1 | chr11 | GO:0007169 | Not Cancer Driver | No | 57 | 0.105 | 299 | 30 | 0.1 | 2 |
| PAK2 | PAK2 | Q13177 | Serine/threonine-protein kinase PAK 2 | chr3 | GO:0007169 | Compendium | Yes | 89 | 0.17 | 242 | 49 | 0.202 | 0 |
| PAK3_ENST00000262836 | PAK3 | O75914 | Serine/threonine-protein kinase PAK 3 | chrX | GO:0007169 | Not Cancer Driver | No | 127 | 0.227 | 286 | 64 | 0.224 | 2 |
| PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0007169 | Not Cancer Driver | No | 21 | 0.11 | 24 | 1 | 0.042 | 0 |
| PDGFA | PDGFA | P04085 | Platelet-derived growth factor subunit A | chr7 | GO:0007169 | Not Cancer Driver | No | 31 | 0.147 | 75 | 10 | 0.133 | 0 |
| PDGFB | PDGFB | P01127 | Platelet-derived growth factor subunit B | chr22 | GO:0007169 | Census | Yes | 37 | 0.154 | 99 | 22 | 0.222 | 2 |
| PDGFC | PDGFC | Q9NRA1 | Platelet-derived growth factor C | chr4 | GO:0007169 | Not Cancer Driver | No | 86 | 0.249 | 53 | 12 | 0.226 | 0 |
| PDGFD | PDGFD | Q9GZP0 | Platelet-derived growth factor D | chr11 | GO:0007169 | Not Cancer Driver | No | 85 | 0.23 | 37 | 13 | 0.351 | 0 |
| PDGFRA | PDGFRA | P16234 | Platelet-derived growth factor receptor alpha | chr4 | GO:0007169 | Census, Compendium | Yes | 290 | 0.266 | 173 | 45 | 0.26 | 2 |
| PDGFRB | PDGFRB | P09619 | Platelet-derived growth factor receptor beta | chr5 | GO:0007169 | Census, Compendium | Yes | 164 | 0.148 | 231 | 44 | 0.19 | 7 |
| PDGFRL | PDGFRL | Q15198 | Platelet-derived growth factor receptor-like protein | chr8 | GO:0007169 | Not Cancer Driver | No | 46 | 0.123 | 67 | 12 | 0.179 | 1 |
| PGF_ENST00000405431 | PGF | P49763 | Placenta growth factor | chr14 | GO:0007169 | Not Cancer Driver | No | 30 | 0.136 | 72 | 10 | 0.139 | 0 |
| PIK3C2A | PIK3C2A | O00443 | Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha | chr11 | GO:0007169 | Not Cancer Driver | No | 187 | 0.111 | 350 | 43 | 0.123 | 0 |
| PIK3CA | PIK3CA | P42336 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | chr3 | GO:0007169 | Census, Compendium | Yes | 1669 | 1.563 | 38 | 11 | 0.289 | 30 |
| PIK3CB_ENST00000477593 | PIK3CB | P42338 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | chr3 | GO:0007169 | Census, Compendium | Yes | 150 | 0.14 | 42 | 4 | 0.095 | 0 |
| PIK3CD | PIK3CD | O00329 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | chr1 | GO:0007169 | Not Cancer Driver | No | 140 | 0.134 | 60 | 13 | 0.217 | 1 |
| PIK3R1 | PIK3R1 | P27986 | Phosphatidylinositol 3-kinase regulatory subunit alpha | chr5 | GO:0007169 | Census, Compendium | Yes | 154 | 0.213 | 268 | 61 | 0.228 | 2 |
| PILRB | PILRB | Q9UKJ0 | Paired immunoglobulin-like type 2 receptor beta | chr7 | GO:0007169 | Not Cancer Driver | No | 29 | 0.128 | 26 | 3 | 0.115 | 0 |
| PLAT | PLAT | P00750 | Tissue-type plasminogen activator | chr8 | GO:0007169 | Not Cancer Driver | No | 89 | 0.158 | 15 | 2 | 0.133 | 0 |
| PLCB1 | PLCB1 | Q9NQ66 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 | chr20 | GO:0007169 | Not Cancer Driver | No | 313 | 0.257 | 481 | 104 | 0.216 | 0 |
| PLEKHA1 | PLEKHA1 | Q9HB21 | Pleckstrin homology domain-containing family A member 1 | chr10 | GO:0007169 | Not Cancer Driver | No | 61 | 0.151 | 191 | 32 | 0.168 | 0 |
| PRKD1_ENST00000616995 | PRKD1 | Q15139 | Serine/threonine-protein kinase D1 | chr14 | GO:0007169 | Census | Yes | 201 | 0.22 | 189 | 33 | 0.175 | 2 |
| PRKD2_ENST00000291281 | PRKD2 | Q9BZL6 | Serine/threonine-protein kinase D2 | chr19 | GO:0007169 | Compendium | Yes | 118 | 0.134 | 246 | 34 | 0.138 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0007169 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| PTK2_ENST00000522684 | PTK2 | Q05397 | Focal adhesion kinase 1 | chr8 | GO:0007169 | Not Cancer Driver | No | 134 | 0.127 | 425 | 55 | 0.129 | 0 |
| PTK6 | PTK6 | Q13882 | Protein-tyrosine kinase 6 | chr20 | GO:0007169 | Census | Yes | 42 | 0.093 | 12 | 0 | 0.0 | 0 |
| PTPN1 | PTPN1 | P18031 | Tyrosine-protein phosphatase non-receptor type 1 | chr20 | GO:0007169 | Not Cancer Driver | No | 49 | 0.113 | 140 | 25 | 0.179 | 0 |
| PTPN11_ENST00000351677 | PTPN11 | Q06124 | Tyrosine-protein phosphatase non-receptor type 11 | chr12 | GO:0007169 | Census, Compendium | Yes | 129 | 0.218 | 260 | 38 | 0.146 | 60 |
| PTPRG | PTPRG | P23470 | Receptor-type tyrosine-protein phosphatase gamma | chr3 | GO:0007169 | Not Cancer Driver | No | 212 | 0.147 | 465 | 61 | 0.131 | 0 |
| PTPRJ | PTPRJ | Q12913 | Receptor-type tyrosine-protein phosphatase eta | chr11 | GO:0007169 | Not Cancer Driver | No | 184 | 0.138 | 401 | 61 | 0.152 | 0 |
| PTPRR | PTPRR | Q15256 | Receptor-type tyrosine-protein phosphatase R | chr12 | GO:0007169 | Not Cancer Driver | No | 172 | 0.262 | 73 | 28 | 0.384 | 0 |
| PTPRT_ENST00000373187 | PTPRT | O14522 | Receptor-type tyrosine-protein phosphatase T | chr20 | GO:0007169 | Census, Compendium | Yes | 535 | 0.371 | 299 | 125 | 0.418 | 0 |
| PXN_ENST00000228307 | PXN | P49023 | Paxillin | chr12 | GO:0007169 | Not Cancer Driver | No | 62 | 0.105 | 341 | 24 | 0.07 | 0 |
| RAC1_ENST00000348035 | RAC1 | P63000 | Ras-related C3 botulinum toxin substrate 1 | chr7 | GO:0007169 | Census, Compendium | Yes | 66 | 0.344 | 2 | 1 | 0.5 | 6 |
| RAF1 | RAF1 | P04049 | RAF proto-oncogene serine/threonine-protein kinase | chr3 | GO:0007169 | Census, Compendium | Yes | 89 | 0.137 | 169 | 38 | 0.225 | 22 |
| RAPGEF1_ENST00000372189 | RAPGEF1 | Q13905 | Rap guanine nucleotide exchange factor 1 | chr9 | GO:0007169 | Not Cancer Driver | No | 158 | 0.147 | 589 | 87 | 0.148 | 0 |
| RAPGEF2 | RAPGEF2 | Q9Y4G8 | Rap guanine nucleotide exchange factor 2 | chr4 | GO:0007169 | Not Cancer Driver | No | 216 | 0.144 | 803 | 116 | 0.144 | 0 |
| RASA1 | RASA1 | P20936 | Ras GTPase-activating protein 1 | chr5 | GO:0007169 | Compendium | Yes | 154 | 0.147 | 181 | 25 | 0.138 | 3 |
| RASGRP4_ENST00000587738 | RASGRP4 | Q8TDF6 | RAS guanyl-releasing protein 4 | chr19 | GO:0007169 | Not Cancer Driver | No | 96 | 0.143 | 184 | 40 | 0.217 | 0 |
| RASSF2 | RASSF2 | P50749 | Ras association domain-containing protein 2 | chr20 | GO:0007169 | Not Cancer Driver | No | 90 | 0.276 | 126 | 44 | 0.349 | 0 |
| RET | RET | P07949 | Proto-oncogene tyrosine-protein kinase receptor Ret | chr10 | GO:0007169 | Census, Compendium | Yes | 208 | 0.187 | 105 | 12 | 0.114 | 139 |
| RGS14 | RGS14 | O43566 | Regulator of G-protein signaling 14 | chr5 | GO:0007169 | Not Cancer Driver | No | 57 | 0.101 | 309 | 37 | 0.12 | 0 |
| ROR1 | ROR1 | Q01973 | Inactive tyrosine-protein kinase transmembrane receptor ROR1 | chr1 | GO:0007169 | Not Cancer Driver | No | 144 | 0.154 | 280 | 43 | 0.154 | 1 |
| ROR2 | ROR2 | Q01974 | Tyrosine-protein kinase transmembrane receptor ROR2 | chr9 | GO:0007169 | Not Cancer Driver | No | 203 | 0.215 | 299 | 71 | 0.237 | 5 |
| ROS1 | ROS1 | P08922 | Proto-oncogene tyrosine-protein kinase ROS | chr6 | GO:0007169 | Census | Yes | 498 | 0.212 | 191 | 55 | 0.288 | 0 |
| RYK_ENST00000623711 | RYK | P34925 | Tyrosine-protein kinase RYK | chr3 | GO:0007169 | Not Cancer Driver | No | 55 | 0.091 | 85 | 4 | 0.047 | 0 |
| SAMD10 | SAMD10 | Q9BYL1 | Sterile alpha motif domain-containing protein 10 | chr20 | GO:0007169 | Not Cancer Driver | No | 17 | 0.084 | 80 | 3 | 0.037 | 0 |
| SAMD12 | SAMD12 | Q8N8I0 | Sterile alpha motif domain-containing protein 12 | chr8 | GO:0007169 | Not Cancer Driver | No | 46 | 0.229 | 60 | 11 | 0.183 | 0 |
| SGPL1 | SGPL1 | O95470 | Sphingosine-1-phosphate lyase 1 | chr10 | GO:0007169 | Not Cancer Driver | No | 68 | 0.12 | 19 | 3 | 0.158 | 2 |
| SH2B1 | SH2B1 | Q9NRF2 | SH2B adapter protein 1 | chr16 | GO:0007169 | Not Cancer Driver | No | 98 | 0.13 | 612 | 84 | 0.137 | 0 |
| SH2B3 | SH2B3 | Q9UQQ2 | SH2B adapter protein 3 | chr12 | GO:0007169 | Census, Compendium | Yes | 48 | 0.083 | 333 | 19 | 0.057 | 0 |
| SHC1_ENST00000368445 | SHC1 | P29353 | SHC-transforming protein 1 | chr1 | GO:0007169 | Not Cancer Driver | No | 84 | 0.144 | 397 | 58 | 0.146 | 0 |
| SHC2 | SHC2 | P98077 | SHC-transforming protein 2 | chr19 | GO:0007169 | Not Cancer Driver | No | 66 | 0.113 | 362 | 44 | 0.122 | 0 |
| SHC3 | SHC3 | Q92529 | SHC-transforming protein 3 | chr9 | GO:0007169 | Not Cancer Driver | No | 94 | 0.158 | 432 | 64 | 0.148 | 0 |
| SHC4 | SHC4 | Q6S5L8 | SHC-transforming protein 4 | chr15 | GO:0007169 | Not Cancer Driver | No | 74 | 0.117 | 325 | 44 | 0.135 | 0 |
| SIPA1L1 | SIPA1L1 | O43166 | Signal-induced proliferation-associated 1-like protein 1 | chr14 | GO:0007169 | Not Cancer Driver | No | 321 | 0.178 | 1175 | 226 | 0.192 | 0 |
| SIRT2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | chr19 | GO:0007169 | Not Cancer Driver | No | 56 | 0.144 | 85 | 17 | 0.2 | 0 |
| SLA_ENST00000338087 | SLA | Q13239 | Src-like-adapter | chr8 | GO:0007169 | Not Cancer Driver | No | 59 | 0.214 | 51 | 11 | 0.216 | 0 |
| SMPD3 | SMPD3 | Q9NY59 | Sphingomyelin phosphodiesterase 3 | chr16 | GO:0007169 | Not Cancer Driver | No | 92 | 0.14 | 224 | 29 | 0.129 | 0 |
| SOCS2_ENST00000536696 | SOCS2 | O14508 | Suppressor of cytokine signaling 2 | chr12 | GO:0007169 | Not Cancer Driver | No | 32 | 0.162 | 61 | 2 | 0.033 | 0 |
| SORT1 | SORT1 | Q99523 | Sortilin | chr1 | GO:0007169 | Not Cancer Driver | No | 69 | 0.083 | 110 | 2 | 0.018 | 0 |
| SOS1_ENST00000402219 | SOS1 | Q07889 | Son of sevenless homolog 1 | chr2 | GO:0007169 | Compendium | Yes | 197 | 0.148 | 458 | 62 | 0.135 | 38 |
| SRC_ENST00000358208 | SRC | P12931 | Proto-oncogene tyrosine-protein kinase Src | chr20 | GO:0007169 | Census | Yes | 53 | 0.099 | 130 | 11 | 0.085 | 1 |
| SRMS | SRMS | Q9H3Y6 | Tyrosine-protein kinase Srms | chr20 | GO:0007169 | Not Cancer Driver | No | 77 | 0.158 | 48 | 11 | 0.229 | 0 |
| SS18 | SS18 | Q15532 | Protein SSXT | chr18 | GO:0007169 | Census | Yes | 52 | 0.124 | 416 | 52 | 0.125 | 0 |
| STAP1_ENST00000396225 | STAP1 | Q9ULZ2 | Signal-transducing adaptor protein 1 | chr4 | GO:0007169 | Not Cancer Driver | No | 66 | 0.224 | 103 | 18 | 0.175 | 0 |
| STAT3 | STAT3 | P40763 | Signal transducer and activator of transcription 3 | chr17 | GO:0007169 | Census, Compendium | Yes | 110 | 0.143 | 152 | 15 | 0.099 | 19 |
| STAT5A_ENST00000590949 | STAT5A | P42229 | Signal transducer and activator of transcription 5A | chr17 | GO:0007169 | Not Cancer Driver | No | 89 | 0.112 | 125 | 14 | 0.112 | 0 |
| STAT5B | STAT5B | P51692 | Signal transducer and activator of transcription 5B | chr17 | GO:0007169 | Census, Compendium | Yes | 93 | 0.118 | 144 | 19 | 0.132 | 5 |
| STAT6_ENST00000543873 | STAT6 | P42226 | Signal transducer and activator of transcription 6 | chr12 | GO:0007169 | Census, Compendium | Yes | 106 | 0.125 | 325 | 44 | 0.135 | 0 |
| STMN1_ENST00000357865 | STMN1 | P16949 | Stathmin | chr1 | GO:0007169 | Not Cancer Driver | No | 15 | 0.101 | 149 | 15 | 0.101 | 0 |
| STUB1 | STUB1 | Q9UNE7 | E3 ubiquitin-protein ligase CHIP | chr16 | GO:0007169 | Not Cancer Driver | No | 35 | 0.116 | 112 | 14 | 0.125 | 12 |
| STYK1 | STYK1 | Q6J9G0 | Tyrosine-protein kinase STYK1 | chr12 | GO:0007169 | Not Cancer Driver | No | 83 | 0.197 | 35 | 10 | 0.286 | 0 |
| SULF1_ENST00000458141 | SULF1 | Q8IWU6 | Extracellular sulfatase Sulf-1 | chr8 | GO:0007169 | Not Cancer Driver | No | 246 | 0.282 | 269 | 71 | 0.264 | 0 |
| SULF2_ENST00000484875 | SULF2 | Q8IWU5 | Extracellular sulfatase Sulf-2 | chr20 | GO:0007169 | Not Cancer Driver | No | 145 | 0.167 | 142 | 18 | 0.127 | 0 |
| SVEP1 | SVEP1 | Q4LDE5 | Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 | chr9 | GO:0007169 | Not Cancer Driver | No | 626 | 0.175 | 229 | 33 | 0.144 | 0 |
| SYK_ENST00000375746 | SYK | P43405 | Tyrosine-protein kinase SYK | chr9 | GO:0007169 | Census | Yes | 96 | 0.151 | 131 | 27 | 0.206 | 5 |
| TEK | TEK | Q02763 | Angiopoietin-1 receptor | chr9 | GO:0007169 | Not Cancer Driver | No | 219 | 0.195 | 126 | 22 | 0.175 | 10 |
| TIAM1 | TIAM1 | Q13009 | Rho guanine nucleotide exchange factor TIAM1 | chr21 | GO:0007169 | Not Cancer Driver | No | 370 | 0.233 | 810 | 194 | 0.24 | 0 |
| TIE1 | TIE1 | P35590 | Tyrosine-protein kinase receptor Tie-1 | chr1 | GO:0007169 | Not Cancer Driver | No | 200 | 0.176 | 223 | 46 | 0.206 | 0 |
| TIPARP | TIPARP | Q7Z3E1 | Protein mono-ADP-ribosyltransferase TIPARP | chr3 | GO:0007169 | Not Cancer Driver | No | 65 | 0.099 | 200 | 20 | 0.1 | 0 |
| TNK1 | TNK1 | Q13470 | Non-receptor tyrosine-protein kinase TNK1 | chr17 | GO:0007169 | Not Cancer Driver | No | 51 | 0.077 | 298 | 24 | 0.081 | 0 |
| TNK2_ENST00000333602 | TNK2 | Q07912 | Activated CDC42 kinase 1 | chr3 | GO:0007169 | Not Cancer Driver | No | 137 | 0.132 | 593 | 81 | 0.137 | 0 |
| TRADD | TRADD | Q15628 | Tumor necrosis factor receptor type 1-associated DEATH domain protein | chr16 | GO:0007169 | Not Cancer Driver | No | 26 | 0.083 | 74 | 5 | 0.068 | 0 |
| TRAT1 | TRAT1 | Q6PIZ9 | T-cell receptor-associated transmembrane adapter 1 | chr3 | GO:0007169 | Not Cancer Driver | No | 86 | 0.462 | 129 | 67 | 0.519 | 0 |
| TSC2 | TSC2 | P49815 | Tuberin | chr16 | GO:0007169 | Census, Compendium | Yes | 192 | 0.106 | 563 | 50 | 0.089 | 53 |
| TXNIP | TXNIP | Q9H3M7 | Thioredoxin-interacting protein | chr1 | GO:0007169 | Not Cancer Driver | No | 61 | 0.156 | 77 | 14 | 0.182 | 0 |
| TYK2 | TYK2 | P29597 | Non-receptor tyrosine-protein kinase TYK2 | chr19 | GO:0007169 | Not Cancer Driver | No | 148 | 0.125 | 213 | 29 | 0.136 | 0 |
| TYRO3 | TYRO3 | Q06418 | Tyrosine-protein kinase receptor TYRO3 | chr15 | GO:0007169 | Not Cancer Driver | No | 119 | 0.134 | 197 | 17 | 0.086 | 0 |
| UBASH3B | UBASH3B | Q8TF42 | Ubiquitin-associated and SH3 domain-containing protein B | chr11 | GO:0007169 | Not Cancer Driver | No | 86 | 0.133 | 73 | 6 | 0.082 | 0 |
| VAV1 | VAV1 | P15498 | Proto-oncogene vav | chr19 | GO:0007169 | Census, Compendium | Yes | 165 | 0.195 | 113 | 19 | 0.168 | 0 |
| VAV2 | VAV2 | P52735 | Guanine nucleotide exchange factor VAV2 | chr9 | GO:0007169 | Not Cancer Driver | No | 127 | 0.145 | 135 | 17 | 0.126 | 0 |
| VEGFA_ENST00000523873 | VEGFA | P15692 | Vascular endothelial growth factor A | chr6 | GO:0007169 | Not Cancer Driver | No | 27 | 0.116 | 41 | 7 | 0.171 | 0 |
| VEGFB | VEGFB | P49765 | Vascular endothelial growth factor B | chr11 | GO:0007169 | Not Cancer Driver | No | 25 | 0.121 | 125 | 22 | 0.176 | 0 |
| VEGFC | VEGFC | P49767 | Vascular endothelial growth factor C | chr4 | GO:0007169 | Not Cancer Driver | No | 128 | 0.305 | 37 | 12 | 0.324 | 0 |
| VEGFD | VEGFD | O43915 | Vascular endothelial growth factor D | chrX | GO:0007169 | Not Cancer Driver | No | 59 | 0.167 | 33 | 6 | 0.182 | 0 |
| YES1_ENST00000314574 | YES1 | P07947 | Tyrosine-protein kinase Yes | chr18 | GO:0007169 | Not Cancer Driver | No | 65 | 0.12 | 62 | 10 | 0.161 | 0 |
| ZAP70 | ZAP70 | P43403 | Tyrosine-protein kinase ZAP-70 | chr2 | GO:0007169 | Not Cancer Driver | No | 126 | 0.204 | 117 | 17 | 0.145 | 8 |
| ZFAND5 | ZFAND5 | O76080 | AN1-type zinc finger protein 5 | chr9 | GO:0007169 | Not Cancer Driver | No | 31 | 0.146 | 162 | 19 | 0.117 | 0 |
| ZFYVE27_ENST00000393677 | ZFYVE27 | Q5T4F4 | Protrudin | chr10 | GO:0007169 | Not Cancer Driver | No | 45 | 0.109 | 140 | 22 | 0.157 | 1 |