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Total number of protein in "GO:0007162" GO term:  225

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABAT_ENST00000268251 ABAT P80404 4-aminobutyrate aminotransferase, mitochondrial chr16 GO:0007162 Not Cancer Driver No 84 0.168 28 5 0.179 1
ABCA12 ABCA12 Q86UK0 Glucosylceramide transporter ABCA12 chr2 GO:0007162 Not Cancer Driver No 511 0.197 136 23 0.169 14
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0007162 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACTN4 ACTN4 O43707 Alpha-actinin-4 chr19 GO:0007162 Not Cancer Driver No 131 0.144 244 42 0.172 8
ACVRL1 ACVRL1 P37023 Serine/threonine-protein kinase receptor R3 chr12 GO:0007162 Not Cancer Driver No 93 0.185 60 11 0.183 82
ADAM10 ADAM10 O14672 Disintegrin and metalloproteinase domain-containing protein 10 chr15 GO:0007162 Not Cancer Driver No 88 0.118 156 20 0.128 4
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0007162 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAM22 ADAM22 Q9P0K1 Disintegrin and metalloproteinase domain-containing protein 22 chr7 GO:0007162 Not Cancer Driver No 189 0.209 222 43 0.194 0
ADAMDEC1 ADAMDEC1 O15204 ADAM DEC1 chr8 GO:0007162 Not Cancer Driver No 117 0.249 106 30 0.283 0
ADAMTS18 ADAMTS18 Q8TE60 A disintegrin and metalloproteinase with thrombospondin motifs 18 chr16 GO:0007162 Not Cancer Driver No 382 0.313 142 63 0.444 2
ADIPOQ ADIPOQ Q15848 Adiponectin chr3 GO:0007162 Not Cancer Driver No 39 0.16 92 21 0.228 1
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0007162 Not Cancer Driver No 61 0.148 93 11 0.118 0
AJAP1 AJAP1 Q9UKB5 Adherens junction-associated protein 1 chr1 GO:0007162 Not Cancer Driver No 103 0.251 271 64 0.236 0
AKNA_ENST00000374088 AKNA Q7Z591 Microtubule organization protein AKNA chr9 GO:0007162 Not Cancer Driver No 180 0.125 1400 178 0.127 0
ALOX12 ALOX12 P18054 Polyunsaturated fatty acid lipoxygenase ALOX12 chr17 GO:0007162 Not Cancer Driver No 73 0.11 73 12 0.164 0
ANGPT1 ANGPT1 Q15389 Angiopoietin-1 chr8 GO:0007162 Not Cancer Driver No 130 0.261 131 24 0.183 1
ANGPT2 ANGPT2 O15123 Angiopoietin-2 chr8 GO:0007162 Not Cancer Driver No 63 0.127 96 10 0.104 1
ANXA1_ENST00000257497 ANXA1 P04083 Annexin A1 chr9 GO:0007162 Not Cancer Driver No 59 0.171 61 12 0.197 0
AP1AR AP1AR Q63HQ0 AP-1 complex-associated regulatory protein chr4 GO:0007162 Not Cancer Driver No 24 0.079 257 24 0.093 0
APOA1_ENST00000375320 APOA1 P02647 Apolipoprotein A-I chr11 GO:0007162 Not Cancer Driver No 28 0.105 131 8 0.061 3
APOD APOD P05090 Apolipoprotein D chr3 GO:0007162 Not Cancer Driver No 34 0.18 13 2 0.154 0
ARG1_ENST00000368087 ARG1 P05089 Arginase-1 chr6 GO:0007162 Not Cancer Driver No 41 0.127 83 12 0.145 9
ARG2 ARG2 P78540 Arginase-2, mitochondrial chr14 GO:0007162 Not Cancer Driver No 25 0.071 58 3 0.052 0
ARHGAP6 ARHGAP6 O43182 Rho GTPase-activating protein 6 chrX GO:0007162 Not Cancer Driver No 168 0.172 680 118 0.174 0
ARHGDIA_ENST00000580685 ARHGDIA P52565 Rho GDP-dissociation inhibitor 1 chr17 GO:0007162 Not Cancer Driver No 25 0.123 50 6 0.12 0
ARHGDIB ARHGDIB P52566 Rho GDP-dissociation inhibitor 2 chr12 GO:0007162 Not Cancer Driver No 33 0.164 92 13 0.141 0
ARHGDIG ARHGDIG Q99819 Rho GDP-dissociation inhibitor 3 chr16 GO:0007162 Not Cancer Driver No 11 0.049 13 1 0.077 0
ATP5F1B ATP5F1B P06576 ATP synthase subunit beta, mitochondrial chr12 GO:0007162 Not Cancer Driver No 60 0.113 85 8 0.094 0
BCAS3_ENST00000390652 BCAS3 Q9H6U6 BCAS3 microtubule associated cell migration factor chr17 GO:0007162 Not Cancer Driver No 134 0.144 417 67 0.161 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0007162 Census, Compendium Yes 134 0.19 328 67 0.204 0
BMP2 BMP2 P12643 Bone morphogenetic protein 2 chr20 GO:0007162 Not Cancer Driver No 73 0.184 139 26 0.187 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0007162 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMP6 BMP6 P22004 Bone morphogenetic protein 6 chr6 GO:0007162 Not Cancer Driver No 95 0.185 226 51 0.226 0
BTN2A2 BTN2A2 Q8WVV5 Butyrophilin subfamily 2 member A2 chr6 GO:0007162 Not Cancer Driver No 92 0.176 24 2 0.083 0
C1QTNF1_ENST00000581774 C1QTNF1 Q9BXJ1 Complement C1q tumor necrosis factor-related protein 1 chr17 GO:0007162 Not Cancer Driver No 61 0.217 96 17 0.177 0
CASK_ENST00000378163 CASK O14936 Peripheral plasma membrane protein CASK chrX GO:0007162 Not Cancer Driver No 118 0.127 285 45 0.158 4
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0007162 Census Yes 32 0.116 62 5 0.081 0
CBFB_ENST00000290858 CBFB Q13951 Core-binding factor subunit beta chr16 GO:0007162 Census, Compendium Yes 39 0.214 94 17 0.181 0
CBLB CBLB Q13191 E3 ubiquitin-protein ligase CBL-B chr3 GO:0007162 Census Yes 160 0.163 562 104 0.185 0
CBLL1 CBLL1 Q75N03 E3 ubiquitin-protein ligase Hakai chr7 GO:0007162 Not Cancer Driver No 72 0.147 373 49 0.131 0
CCL21 CCL21 O00585 C-C motif chemokine 21 chr9 GO:0007162 Not Cancer Driver No 14 0.104 59 6 0.102 0
CCL25 CCL25 O15444 C-C motif chemokine 25 chr19 GO:0007162 Not Cancer Driver No 20 0.133 26 6 0.231 0
CCL28 CCL28 Q9NRJ3 C-C motif chemokine 28 chr5 GO:0007162 Not Cancer Driver No 17 0.134 48 8 0.167 0
CD164 CD164 Q04900 Sialomucin core protein 24 chr6 GO:0007162 Not Cancer Driver No 14 0.071 64 4 0.062 0
CD274 CD274 Q9NZQ7 Programmed cell death 1 ligand 1 chr9 GO:0007162 Census Yes 29 0.1 54 9 0.167 0
CD300A CD300A Q9UGN4 CMRF35-like molecule 8 chr17 GO:0007162 Not Cancer Driver No 53 0.177 70 10 0.143 0
CD74 CD74 P04233 HLA class II histocompatibility antigen gamma chain chr5 GO:0007162 Census Yes 31 0.105 185 20 0.108 0
CD9 CD9 P21926 CD9 antigen chr12 GO:0007162 Not Cancer Driver No 22 0.096 0 0 0.0 0
CDH13_ENST00000567109 CDH13 P55290 Cadherin-13 chr16 GO:0007162 Not Cancer Driver No 168 0.236 235 59 0.251 0
CDKN2A_ENST00000304494 CDKN2A P42771 Cyclin-dependent kinase inhibitor 2A chr9 GO:0007162 Census, Compendium Yes 166 1.064 83 88 1.06 36
CDSN CDSN Q15517 Corneodesmosin chr6 GO:0007162 Not Cancer Driver No 56 0.106 469 52 0.111 0
CEACAM1 CEACAM1 P13688 Carcinoembryonic antigen-related cell adhesion molecule 1 chr19 GO:0007162 Not Cancer Driver No 64 0.122 241 25 0.104 0
CLASP2 CLASP2 O75122 CLIP-associating protein 2 chr3 GO:0007162 Not Cancer Driver No 158 0.122 676 94 0.139 0
COL1A1 COL1A1 P02452 Collagen alpha-1(I) chain chr17 GO:0007162 Census, Compendium Yes 247 0.169 1212 214 0.177 148
CORO1C_ENST00000541050 CORO1C Q9ULV4 Coronin-1C chr12 GO:0007162 Not Cancer Driver No 61 0.129 84 13 0.155 0
CORO2B CORO2B Q9UQ03 Coronin-2B chr15 GO:0007162 Not Cancer Driver No 85 0.177 37 7 0.189 0
CRTAM CRTAM O95727 Cytotoxic and regulatory T-cell molecule chr11 GO:0007162 Not Cancer Driver No 64 0.163 135 14 0.104 0
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0007162 Not Cancer Driver No 37 0.166 3 0 0.0 1
CX3CL1 CX3CL1 P78423 Fractalkine chr16 GO:0007162 Not Cancer Driver No 66 0.166 259 44 0.17 0
CXCL12_ENST00000374429 CXCL12 P48061 Stromal cell-derived factor 1 chr10 GO:0007162 Not Cancer Driver No 16 0.172 0 0 0.0 0
CYP1B1 CYP1B1 Q16678 Cytochrome P450 1B1 chr2 GO:0007162 Not Cancer Driver No 61 0.112 31 3 0.097 40
DAB1_ENST00000371231 DAB1 O75553 Disabled homolog 1 chr1 GO:0007162 Not Cancer Driver No 200 0.34 393 143 0.364 0
DACT2 DACT2 Q5SW24 Dapper homolog 2 chr6 GO:0007162 Not Cancer Driver No 35 0.045 655 30 0.046 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0007162 Not Cancer Driver No 331 0.217 922 237 0.257 0
DMTN_ENST00000358242 DMTN Q08495 Dematin chr8 GO:0007162 Not Cancer Driver No 53 0.131 348 46 0.132 0
DSCAM DSCAM O60469 Down syndrome cell adhesion molecule chr21 GO:0007162 Not Cancer Driver No 652 0.324 603 201 0.333 0
DUSP1 DUSP1 P28562 Dual specificity protein phosphatase 1 chr5 GO:0007162 Not Cancer Driver No 31 0.084 7 0 0.0 0
DUSP22_ENST00000344450 DUSP22 Q9NRW4 Dual specificity protein phosphatase 22 chr6 GO:0007162 Not Cancer Driver No 84 0.457 0 0 0.0 0
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0007162 Not Cancer Driver No 34 0.149 25 6 0.24 0
EPCAM EPCAM P16422 Epithelial cell adhesion molecule chr2 GO:0007162 Not Cancer Driver No 40 0.127 25 2 0.08 1
EPHA4_ENST00000409938 EPHA4 P54764 Ephrin type-A receptor 4 chr2 GO:0007162 Not Cancer Driver No 182 0.185 140 24 0.171 0
EPHB2 EPHB2 P29323 Ephrin type-B receptor 2 chr1 GO:0007162 Not Cancer Driver No 186 0.176 119 17 0.143 7
ERBB2 ERBB2 P04626 Receptor tyrosine-protein kinase erbB-2 chr17 GO:0007162 Census, Compendium Yes 275 0.219 314 41 0.131 1
ERBB3 ERBB3 P21860 Receptor tyrosine-protein kinase erbB-3 chr12 GO:0007162 Census, Compendium Yes 298 0.222 396 70 0.177 3
FAM107A_ENST00000394481 FAM107A O95990 Actin-associated protein FAM107A chr3 GO:0007162 Not Cancer Driver No 25 0.174 141 24 0.17 0
FBLN1 FBLN1 P23142 Fibulin-1 chr22 GO:0007162 Compendium Yes 122 0.174 22 3 0.136 0
FCGR2B FCGR2B P31994 Low affinity immunoglobulin gamma Fc region receptor II-b chr1 GO:0007162 Census Yes 51 0.165 99 30 0.303 0
FGG FGG P02679 Fibrinogen gamma chain chr4 GO:0007162 Not Cancer Driver No 81 0.179 53 8 0.151 8
FGL2 FGL2 Q14314 Fibroleukin chr7 GO:0007162 Not Cancer Driver No 71 0.162 70 12 0.171 0
FOXJ1 FOXJ1 Q92949 Forkhead box protein J1 chr17 GO:0007162 Not Cancer Driver No 25 0.059 279 18 0.065 0
FOXP3 FOXP3 Q9BZS1 Forkhead box protein P3 chrX GO:0007162 Not Cancer Driver No 38 0.088 186 16 0.086 10
FXYD5_ENST00000590686 FXYD5 Q96DB9 FXYD domain-containing ion transport regulator 5 chr19 GO:0007162 Not Cancer Driver No 31 0.174 136 18 0.132 0
FZD4 FZD4 Q9ULV1 Frizzled-4 chr11 GO:0007162 Not Cancer Driver No 57 0.106 33 5 0.152 19
FZD7 FZD7 O75084 Frizzled-7 chr2 GO:0007162 Not Cancer Driver No 90 0.157 22 2 0.091 0
GBP1 GBP1 P32455 Guanylate-binding protein 1 chr1 GO:0007162 Not Cancer Driver No 92 0.155 166 27 0.163 0
GCNT2_ENST00000379597 GCNT2 Q8N0V5 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase chr6 GO:0007162 Not Cancer Driver No 40 0.1 3 0 0.0 0
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0007162 Not Cancer Driver No 385 0.244 1352 327 0.242 7
HAVCR2 HAVCR2 Q8TDQ0 Hepatitis A virus cellular receptor 2 chr5 GO:0007162 Not Cancer Driver No 69 0.229 17 2 0.118 3
HFE HFE Q30201 Hereditary hemochromatosis protein chr6 GO:0007162 Not Cancer Driver No 55 0.158 27 2 0.074 11
HLX HLX Q14774 H2.0-like homeobox protein chr1 GO:0007162 Not Cancer Driver No 107 0.219 412 98 0.238 0
HMGB1_ENST00000405805 HMGB1 P09429 High mobility group protein B1 chr13 GO:0007162 Not Cancer Driver No 25 0.116 203 20 0.099 0
HOXA7 HOXA7 P31268 Homeobox protein Hox-A7 chr7 GO:0007162 Not Cancer Driver No 60 0.261 71 15 0.211 0
HRG HRG P04196 Histidine-rich glycoprotein chr3 GO:0007162 Not Cancer Driver No 121 0.23 277 75 0.271 2
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0007162 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNB1 IFNB1 P01574 Interferon beta chr9 GO:0007162 Not Cancer Driver No 46 0.246 0 0 0.0 0
IFNL1 IFNL1 Q8IU54 Interferon lambda-1 chr19 GO:0007162 Not Cancer Driver No 24 0.12 49 8 0.163 0
IHH IHH Q14623 Indian hedgehog protein chr2 GO:0007162 Not Cancer Driver No 58 0.141 111 15 0.135 6
IL10 IL10 P22301 Interleukin-10 chr1 GO:0007162 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL1RN_ENST00000409930 IL1RN P18510 Interleukin-1 receptor antagonist protein chr2 GO:0007162 Not Cancer Driver No 34 0.192 17 7 0.412 0
IL2 IL2 P60568 Interleukin-2 chr4 GO:0007162 Census Yes 24 0.157 6 1 0.167 0
IL4 IL4 P05112 Interleukin-4 chr5 GO:0007162 Not Cancer Driver No 18 0.118 0 0 0.0 0
IL4R_ENST00000543915 IL4R P24394 Interleukin-4 receptor subunit alpha chr16 GO:0007162 Not Cancer Driver No 133 0.161 420 64 0.152 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0007162 Compendium Yes 49 0.151 228 31 0.136 2
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0007162 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGB1BP1_ENST00000355346 ITGB1BP1 O14713 Integrin beta-1-binding protein 1 chr2 GO:0007162 Not Cancer Driver No 26 0.13 58 11 0.19 0
JAG1 JAG1 P78504 Protein jagged-1 chr20 GO:0007162 Not Cancer Driver No 182 0.149 172 20 0.116 52
JAK3 JAK3 P52333 Tyrosine-protein kinase JAK3 chr19 GO:0007162 Census, Compendium Yes 167 0.149 63 10 0.159 7
JAM3 JAM3 Q9BX67 Junctional adhesion molecule C chr11 GO:0007162 Not Cancer Driver No 50 0.161 62 11 0.177 2
KANK1_ENST00000382303 KANK1 Q14678 KN motif and ankyrin repeat domain-containing protein 1 chr9 GO:0007162 Not Cancer Driver No 183 0.135 804 100 0.124 0
KNG1 KNG1 P01042 Kininogen-1 chr3 GO:0007162 Not Cancer Driver No 130 0.202 294 66 0.224 1
LAG3 LAG3 P18627 Lymphocyte activation gene 3 protein chr12 GO:0007162 Not Cancer Driver No 47 0.09 208 11 0.053 0
LGALS3 LGALS3 P17931 Galectin-3 chr14 GO:0007162 Not Cancer Driver No 15 0.06 133 6 0.045 0
LGALS7B LGALS7B P47929 Galectin-7 chr19 GO:0007162 Not Cancer Driver No 14 0.103 54 5 0.093 0
LGALS9 LGALS9 O00182 Galectin-9 chr17 GO:0007162 Not Cancer Driver No 54 0.152 65 16 0.246 0
LGALS9B_ENST00000423676 LGALS9B Q3B8N2 Galectin-9B chr17 GO:0007162 Not Cancer Driver No 43 0.121 86 19 0.221 0
LGALS9C LGALS9C Q6DKI2 Galectin-9C chr17 GO:0007162 Not Cancer Driver No 32 0.09 80 6 0.075 0
LILRB1_ENST00000396331 LILRB1 Q8NHL6 Leukocyte immunoglobulin-like receptor subfamily B member 1 chr19 GO:0007162 Not Cancer Driver No 203 0.312 291 97 0.333 0
LILRB4 LILRB4 Q8NHJ6 Leukocyte immunoglobulin-like receptor subfamily B member 4 chr19 GO:0007162 Not Cancer Driver No 162 0.362 277 115 0.415 0
LOXL3 LOXL3 P58215 Lysyl oxidase homolog 3 chr2 GO:0007162 Not Cancer Driver No 91 0.121 86 17 0.198 0
LPXN_ENST00000395074 LPXN O60711 Leupaxin chr11 GO:0007162 Not Cancer Driver No 43 0.111 134 16 0.119 0
LRRC32_ENST00000404995 LRRC32 Q14392 Transforming growth factor beta activator LRRC32 chr11 GO:0007162 Not Cancer Driver No 130 0.196 28 4 0.143 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0007162 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAP2K5 MAP2K5 Q13163 Dual specificity mitogen-activated protein kinase kinase 5 chr15 GO:0007162 Not Cancer Driver No 40 0.089 85 10 0.118 0
MAP4K4_ENST00000347699 MAP4K4 O95819 Mitogen-activated protein kinase kinase kinase kinase 4 chr2 GO:0007162 Not Cancer Driver No 143 0.115 649 55 0.085 0
MAPK7 MAPK7 Q13164 Mitogen-activated protein kinase 7 chr17 GO:0007162 Not Cancer Driver No 92 0.113 490 50 0.102 0
MBP_ENST00000580402 MBP P02686 Myelin basic protein chr18 GO:0007162 Not Cancer Driver No 52 0.171 304 52 0.171 0
MDK_ENST00000407067 MDK P21741 Midkine chr11 GO:0007162 Not Cancer Driver No 15 0.105 20 2 0.1 0
MELTF MELTF P08582 Melanotransferrin chr3 GO:0007162 Not Cancer Driver No 106 0.144 23 6 0.261 0
MEN1 MEN1 O00255 Menin chr11 GO:0007162 Census, Compendium Yes 73 0.119 228 15 0.066 90
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0007162 Not Cancer Driver No 74 0.128 274 29 0.106 0
MIA3 MIA3 Q5JRA6 Transport and Golgi organization protein 1 homolog chr1 GO:0007162 Not Cancer Driver No 222 0.116 1490 178 0.119 0
MMP12 MMP12 P39900 Macrophage metalloelastase chr11 GO:0007162 Not Cancer Driver No 100 0.213 29 5 0.172 0
MMP14 MMP14 P50281 Matrix metalloproteinase-14 chr14 GO:0007162 Not Cancer Driver No 64 0.11 118 11 0.093 1
MMP2 MMP2 P08253 72 kDa type IV collagenase chr16 GO:0007162 Not Cancer Driver No 123 0.186 29 6 0.207 2
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0007162 Census Yes 40 0.032 1050 19 0.018 0
MYADM MYADM Q96S97 Myeloid-associated differentiation marker chr19 GO:0007162 Not Cancer Driver No 73 0.227 0 0 0.0 0
MYOC MYOC Q99972 Myocilin chr1 GO:0007162 Not Cancer Driver No 92 0.183 196 43 0.219 58
NCKAP1L NCKAP1L P55160 Nck-associated protein 1-like chr12 GO:0007162 Not Cancer Driver No 247 0.219 51 10 0.196 4
NEXMIF_ENST00000616200 NEXMIF Q5QGS0 Neurite extension and migration factor chrX GO:0007162 Not Cancer Driver No 404 0.266 1054 292 0.277 0
NF1 NF1 P21359 Neurofibromin chr17 GO:0007162 Census, Compendium Yes 375 0.132 406 47 0.116 85
NF2 NF2 P35240 Merlin chr22 GO:0007162 Census, Compendium Yes 69 0.116 252 26 0.103 16
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0007162 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH4 NOTCH4 Q99466 Neurogenic locus notch homolog protein 4 chr6 GO:0007162 Not Cancer Driver No 336 0.168 464 79 0.17 0
NRARP NRARP Q7Z6K4 Notch-regulated ankyrin repeat-containing protein chr9 GO:0007162 Not Cancer Driver No 9 0.079 11 1 0.091 0
PDCD1LG2 PDCD1LG2 Q9BQ51 Programmed cell death 1 ligand 2 chr9 GO:0007162 Census, Compendium Yes 33 0.121 41 13 0.317 0
PDE3B PDE3B Q13370 cGMP-inhibited 3',5'-cyclic phosphodiesterase B chr11 GO:0007162 Not Cancer Driver No 135 0.121 393 37 0.094 0
PHLDB2 PHLDB2 Q86SQ0 Pleckstrin homology-like domain family B member 2 chr3 GO:0007162 Not Cancer Driver No 235 0.188 1030 190 0.184 0
PIK3R1 PIK3R1 P27986 Phosphatidylinositol 3-kinase regulatory subunit alpha chr5 GO:0007162 Census, Compendium Yes 154 0.213 268 61 0.228 2
PLET1 PLET1 Q6UQ28 Placenta-expressed transcript 1 protein chr11 GO:0007162 Not Cancer Driver No 8 0.039 0 0 0.0 0
PLG PLG P00747 Plasminogen chr6 GO:0007162 Not Cancer Driver No 242 0.299 230 64 0.278 9
PLXNA1 PLXNA1 Q9UIW2 Plexin-A1 chr3 GO:0007162 Not Cancer Driver No 281 0.148 228 28 0.123 0
PLXNA2 PLXNA2 O75051 Plexin-A2 chr1 GO:0007162 Not Cancer Driver No 312 0.165 142 25 0.176 0
PLXNA3 PLXNA3 P51805 Plexin-A3 chrX GO:0007162 Not Cancer Driver No 243 0.13 199 34 0.171 0
PLXNA4 PLXNA4 Q9HCM2 Plexin-A4 chr7 GO:0007162 Not Cancer Driver No 591 0.312 198 63 0.318 0
PLXNB1_ENST00000296440 PLXNB1 O43157 Plexin-B1 chr3 GO:0007162 Not Cancer Driver No 228 0.107 684 67 0.098 0
PLXNB2_ENST00000359337 PLXNB2 O15031 Plexin-B2 chr22 GO:0007162 Not Cancer Driver No 273 0.149 304 35 0.115 0
PLXNB3_ENST00000361971 PLXNB3 Q9ULL4 Plexin-B3 chrX GO:0007162 Not Cancer Driver No 217 0.114 358 37 0.103 0
PLXNC1 PLXNC1 O60486 Plexin-C1 chr12 GO:0007162 Not Cancer Driver No 205 0.131 135 18 0.133 0
PLXND1 PLXND1 Q9Y4D7 Plexin-D1 chr3 GO:0007162 Not Cancer Driver No 246 0.128 321 35 0.109 0
PODXL PODXL O00592 Podocalyxin chr7 GO:0007162 Not Cancer Driver No 69 0.124 432 56 0.13 0
PPM1F PPM1F P49593 Protein phosphatase 1F chr22 GO:0007162 Not Cancer Driver No 53 0.117 242 24 0.099 0
PRDX2 PRDX2 P32119 Peroxiredoxin-2 chr19 GO:0007162 Not Cancer Driver No 24 0.121 30 4 0.133 0
PRKAR1A_ENST00000536854 PRKAR1A P10644 cAMP-dependent protein kinase type I-alpha regulatory subunit chr17 GO:0007162 Census, Compendium Yes 39 0.102 66 11 0.167 17
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0007162 Compendium Yes 79 0.117 43 9 0.209 0
PRKG1_ENST00000401604 PRKG1 Q13976 cGMP-dependent protein kinase 1 chr10 GO:0007162 Not Cancer Driver No 167 0.249 93 22 0.237 1
PRNP PRNP P04156 Major prion protein chr20 GO:0007162 Not Cancer Driver No 36 0.142 115 7 0.061 18
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0007162 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTPN11_ENST00000351677 PTPN11 Q06124 Tyrosine-protein phosphatase non-receptor type 11 chr12 GO:0007162 Census, Compendium Yes 129 0.218 260 38 0.146 60
PTPN2 PTPN2 P17706 Tyrosine-protein phosphatase non-receptor type 2 chr18 GO:0007162 Not Cancer Driver No 57 0.137 120 14 0.117 0
PTPRC PTPRC P08575 Receptor-type tyrosine-protein phosphatase C chr1 GO:0007162 Census, Compendium Yes 315 0.241 462 107 0.232 0
PTPRO PTPRO Q16827 Receptor-type tyrosine-protein phosphatase O chr12 GO:0007162 Not Cancer Driver No 204 0.168 137 34 0.248 0
RAG2 RAG2 P55895 V(D)J recombination-activating protein 2 chr11 GO:0007162 Not Cancer Driver No 118 0.224 85 23 0.271 6
RASA1 RASA1 P20936 Ras GTPase-activating protein 1 chr5 GO:0007162 Compendium Yes 154 0.147 181 25 0.138 3
RC3H1_ENST00000258349 RC3H1 Q5TC82 Roquin-1 chr1 GO:0007162 Not Cancer Driver No 158 0.139 796 115 0.144 0
RC3H2_ENST00000357244 RC3H2 Q9HBD1 Roquin-2 chr9 GO:0007162 Not Cancer Driver No 128 0.107 703 81 0.115 0
RCC2 RCC2 Q9P258 Protein RCC2 chr1 GO:0007162 Not Cancer Driver No 63 0.121 194 27 0.139 0
RDX_ENST00000343115 RDX P35241 Radixin chr11 GO:0007162 Not Cancer Driver No 71 0.122 297 37 0.125 1
RGCC RGCC Q9H4X1 Regulator of cell cycle RGCC chr13 GO:0007162 Not Cancer Driver No 9 0.066 81 7 0.086 0
RHOA RHOA P61586 Transforming protein RhoA chr3 GO:0007162 Census, Compendium Yes 99 0.513 46 13 0.283 2
RIPOR2_ENST00000259698 RIPOR2 Q9Y4F9 Rho family-interacting cell polarization regulator 2 chr6 GO:0007162 Not Cancer Driver No 131 0.123 421 76 0.181 0
RND1 RND1 Q92730 Rho-related GTP-binding protein Rho6 chr12 GO:0007162 Not Cancer Driver No 45 0.194 9 1 0.111 0
RUNX1_ENST00000344691 RUNX1 Q01196 Runt-related transcription factor 1 chr21 GO:0007162 Census, Compendium Yes 81 0.179 360 58 0.161 2
RUNX3_ENST00000308873 RUNX3 Q13761 Runt-related transcription factor 3 chr1 GO:0007162 Not Cancer Driver No 59 0.142 331 45 0.136 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0007162 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SEMA3E SEMA3E O15041 Semaphorin-3E chr7 GO:0007162 Not Cancer Driver No 195 0.252 86 27 0.314 0
SEMA4D SEMA4D Q92854 Semaphorin-4D chr9 GO:0007162 Not Cancer Driver No 117 0.136 132 15 0.114 0
SEMA5A SEMA5A Q13591 Semaphorin-5A chr5 GO:0007162 Not Cancer Driver No 266 0.248 23 4 0.174 0
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0007162 Not Cancer Driver No 136 0.132 456 72 0.158 0
SERPINE1 SERPINE1 P05121 Plasminogen activator inhibitor 1 chr7 GO:0007162 Not Cancer Driver No 78 0.194 7 2 0.286 0
SERPINE2_ENST00000258405 SERPINE2 P07093 Glia-derived nexin chr2 GO:0007162 Not Cancer Driver No 62 0.156 0 0 0.0 0
SH2B3 SH2B3 Q9UQQ2 SH2B adapter protein 3 chr12 GO:0007162 Census, Compendium Yes 48 0.083 333 19 0.057 0
SHH SHH Q15465 Sonic hedgehog protein chr7 GO:0007162 Not Cancer Driver No 56 0.121 139 14 0.101 81
SIPA1_ENST00000534313 SIPA1 Q96FS4 Signal-induced proliferation-associated protein 1 chr11 GO:0007162 Not Cancer Driver No 67 0.064 666 43 0.065 0
SMAD7 SMAD7 O15105 Mothers against decapentaplegic homolog 7 chr18 GO:0007162 Not Cancer Driver No 40 0.094 139 0 0.0 0
SNAI2_ENST00000020945 SNAI2 O43623 Zinc finger protein SNAI2 chr8 GO:0007162 Not Cancer Driver No 52 0.194 52 9 0.173 0
SOCS1 SOCS1 O15524 Suppressor of cytokine signaling 1 chr16 GO:0007162 Census, Compendium Yes 22 0.104 66 3 0.045 2
SOCS5 SOCS5 O75159 Suppressor of cytokine signaling 5 chr2 GO:0007162 Not Cancer Driver No 84 0.157 297 46 0.155 0
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0007162 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPN_ENST00000395389 SPN P16150 Leukosialin chr16 GO:0007162 Not Cancer Driver No 46 0.115 357 35 0.098 0
SPOCK1 SPOCK1 Q08629 Testican-1 chr5 GO:0007162 Not Cancer Driver No 82 0.187 107 16 0.15 0
SPRY4_ENST00000434127 SPRY4 Q9C004 Protein sprouty homolog 4 chr5 GO:0007162 Not Cancer Driver No 34 0.114 134 20 0.149 7
SRC_ENST00000358208 SRC P12931 Proto-oncogene tyrosine-protein kinase Src chr20 GO:0007162 Census Yes 53 0.099 130 11 0.085 1
SWAP70 SWAP70 Q9UH65 Switch-associated protein 70 chr11 GO:0007162 Not Cancer Driver No 44 0.075 271 18 0.066 0
TACSTD2 TACSTD2 P09758 Tumor-associated calcium signal transducer 2 chr1 GO:0007162 Not Cancer Driver No 22 0.068 27 1 0.037 0
TARM1_ENST00000432826 TARM1 B6A8C7 T-cell-interacting, activating receptor on myeloid cells protein 1 chr19 GO:0007162 Not Cancer Driver No 13 0.048 21 1 0.048 0
TBCD TBCD Q9BTW9 Tubulin-specific chaperone D chr17 GO:0007162 Not Cancer Driver No 156 0.131 60 9 0.15 11
TBX21 TBX21 Q9UL17 T-box transcription factor TBX21 chr17 GO:0007162 Not Cancer Driver No 70 0.131 348 50 0.144 0
TGFBI TGFBI Q15582 Transforming growth factor-beta-induced protein ig-h3 chr5 GO:0007162 Not Cancer Driver No 108 0.158 58 19 0.328 23
THBS1 THBS1 P07996 Thrombospondin-1 chr15 GO:0007162 Not Cancer Driver No 188 0.161 320 58 0.181 0
TMEM131L_ENST00000409663 TMEM131L A2VDJ0 Transmembrane protein 131-like chr4 GO:0007162 Not Cancer Driver No 188 0.117 448 47 0.105 0
TNFRSF14 TNFRSF14 Q92956 Tumor necrosis factor receptor superfamily member 14 chr1 GO:0007162 Census, Compendium Yes 33 0.117 54 8 0.148 0
TNFSF4 TNFSF4 P23510 Tumor necrosis factor ligand superfamily member 4 chr1 GO:0007162 Not Cancer Driver No 28 0.153 1 0 0.0 0
TRPV4 TRPV4 Q9HBA0 Transient receptor potential cation channel subfamily V member 4 chr12 GO:0007162 Not Cancer Driver No 142 0.163 231 34 0.147 44
TWSG1 TWSG1 Q9GZX9 Twisted gastrulation protein homolog 1 chr18 GO:0007162 Not Cancer Driver No 27 0.121 19 3 0.158 0
UBASH3B UBASH3B Q8TF42 Ubiquitin-associated and SH3 domain-containing protein B chr11 GO:0007162 Not Cancer Driver No 86 0.133 73 6 0.082 0
VEGFA_ENST00000523873 VEGFA P15692 Vascular endothelial growth factor A chr6 GO:0007162 Not Cancer Driver No 27 0.116 41 7 0.171 0
VSIR VSIR Q9H7M9 V-type immunoglobulin domain-containing suppressor of T-cell activation chr10 GO:0007162 Not Cancer Driver No 52 0.167 135 19 0.141 0
WNK1_ENST00000315939 WNK1 Q9H4A3 Serine/threonine-protein kinase WNK1 chr12 GO:0007162 Not Cancer Driver No 278 0.117 1959 223 0.114 0
WNT1 WNT1 P04628 Proto-oncogene Wnt-1 chr12 GO:0007162 Not Cancer Driver No 29 0.078 25 0 0.0 8
XCL1 XCL1 P47992 Lymphotactin chr1 GO:0007162 Not Cancer Driver No 28 0.246 35 11 0.314 0
YTHDF2_ENST00000542507 YTHDF2 Q9Y5A9 YTH domain-containing family protein 2 chr1 GO:0007162 Not Cancer Driver No 67 0.116 376 44 0.117 0
ZBTB7B_ENST00000368426 ZBTB7B O15156 Zinc finger and BTB domain-containing protein 7B chr1 GO:0007162 Compendium Yes 103 0.191 353 70 0.198 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0007162 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0007162 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZNF703 ZNF703 Q9H7S9 Zinc finger protein 703 chr8 GO:0007162 Not Cancer Driver No 26 0.044 415 14 0.034 0