Total number of protein in "GO:0006997" GO term: 78
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AFF2 | AFF2 | P51816 | AF4/FMR2 family member 2 | chrX | GO:0006997 | Not Cancer Driver | No | 409 | 0.312 | 1003 | 314 | 0.313 | 0 |
| AHCTF1 | AHCTF1 | Q8WYP5 | Protein ELYS | chr1 | GO:0006997 | Not Cancer Driver | No | 296 | 0.131 | 1060 | 130 | 0.123 | 0 |
| ATXN7_ENST00000487717 | ATXN7 | O15265 | Ataxin-7 | chr3 | GO:0006997 | Not Cancer Driver | No | 95 | 0.107 | 797 | 82 | 0.103 | 0 |
| BIN1 | BIN1 | O00499 | Myc box-dependent-interacting protein 1 | chr2 | GO:0006997 | Not Cancer Driver | No | 65 | 0.11 | 456 | 42 | 0.092 | 5 |
| CDK1 | CDK1 | P06493 | Cyclin-dependent kinase 1 | chr10 | GO:0006997 | Not Cancer Driver | No | 40 | 0.135 | 1 | 0 | 0.0 | 0 |
| CELF3 | CELF3 | Q5SZQ8 | CUGBP Elav-like family member 3 | chr1 | GO:0006997 | Not Cancer Driver | No | 82 | 0.176 | 201 | 33 | 0.164 | 0 |
| CEP55 | CEP55 | Q53EZ4 | Centrosomal protein of 55 kDa | chr10 | GO:0006997 | Not Cancer Driver | No | 59 | 0.127 | 264 | 26 | 0.098 | 0 |
| CHEK1_ENST00000428830 | CHEK1 | O14757 | Serine/threonine-protein kinase Chk1 | chr11 | GO:0006997 | Not Cancer Driver | No | 58 | 0.122 | 86 | 16 | 0.186 | 0 |
| CHMP1A | CHMP1A | Q9HD42 | Charged multivesicular body protein 1a | chr16 | GO:0006997 | Not Cancer Driver | No | 18 | 0.092 | 110 | 6 | 0.055 | 0 |
| CHMP1B | CHMP1B | Q7LBR1 | Charged multivesicular body protein 1b | chr18 | GO:0006997 | Not Cancer Driver | No | 23 | 0.116 | 133 | 16 | 0.12 | 0 |
| CHMP2A_ENST00000601220 | CHMP2A | O43633 | Charged multivesicular body protein 2a | chr19 | GO:0006997 | Not Cancer Driver | No | 29 | 0.131 | 161 | 22 | 0.137 | 0 |
| CHMP2B | CHMP2B | Q9UQN3 | Charged multivesicular body protein 2b | chr3 | GO:0006997 | Not Cancer Driver | No | 28 | 0.131 | 183 | 25 | 0.137 | 4 |
| CHMP3 | CHMP3 | Q9Y3E7 | Charged multivesicular body protein 3 | chr2 | GO:0006997 | Not Cancer Driver | No | 25 | 0.113 | 137 | 13 | 0.095 | 0 |
| CHMP4A_ENST00000609024 | CHMP4A | Q9BY43 | Charged multivesicular body protein 4a | chr14 | GO:0006997 | Not Cancer Driver | No | 24 | 0.108 | 204 | 23 | 0.113 | 0 |
| CHMP4B | CHMP4B | Q9H444 | Charged multivesicular body protein 4b | chr20 | GO:0006997 | Not Cancer Driver | No | 25 | 0.112 | 201 | 22 | 0.109 | 2 |
| CHMP4C | CHMP4C | Q96CF2 | Charged multivesicular body protein 4c | chr8 | GO:0006997 | Not Cancer Driver | No | 33 | 0.142 | 224 | 31 | 0.138 | 0 |
| CHMP5 | CHMP5 | Q9NZZ3 | Charged multivesicular body protein 5 | chr9 | GO:0006997 | Not Cancer Driver | No | 24 | 0.11 | 195 | 18 | 0.092 | 0 |
| CHMP6 | CHMP6 | Q96FZ7 | Charged multivesicular body protein 6 | chr17 | GO:0006997 | Not Cancer Driver | No | 26 | 0.129 | 88 | 16 | 0.182 | 0 |
| CHMP7_ENST00000313219 | CHMP7 | Q8WUX9 | Charged multivesicular body protein 7 | chr8 | GO:0006997 | Not Cancer Driver | No | 50 | 0.11 | 140 | 15 | 0.107 | 0 |
| DMRTC2 | DMRTC2 | Q8IXT2 | Doublesex- and mab-3-related transcription factor C2 | chr19 | GO:0006997 | Not Cancer Driver | No | 45 | 0.123 | 310 | 35 | 0.113 | 0 |
| DYRK3 | DYRK3 | O43781 | Dual specificity tyrosine-phosphorylation-regulated kinase 3 | chr1 | GO:0006997 | Not Cancer Driver | No | 87 | 0.148 | 193 | 20 | 0.104 | 0 |
| EMG1 | EMG1 | Q92979 | Ribosomal RNA small subunit methyltransferase NEP1 | chr12 | GO:0006997 | Not Cancer Driver | No | 28 | 0.115 | 58 | 4 | 0.069 | 1 |
| ETS1_ENST00000319397 | ETS1 | P14921 | Protein C-ets-1 | chr11 | GO:0006997 | Not Cancer Driver | No | 68 | 0.154 | 78 | 9 | 0.115 | 0 |
| FAM118B | FAM118B | Q9BPY3 | Protein FAM118B | chr11 | GO:0006997 | Not Cancer Driver | No | 50 | 0.142 | 37 | 4 | 0.108 | 0 |
| GOLM1_ENST00000388711 | GOLM1 | Q8NBJ4 | Golgi membrane protein 1 | chr9 | GO:0006997 | Not Cancer Driver | No | 46 | 0.115 | 274 | 25 | 0.091 | 0 |
| H1FNT | H1-7 | Q75WM6 | Testis-specific H1 histone | chr12 | GO:0006997 | Not Cancer Driver | No | 54 | 0.212 | 251 | 54 | 0.215 | 0 |
| H3F3A_ENST00000366816 | H3-3B | P84243 | Histone H3.3 | chr1 | GO:0006997 | Not Cancer Driver | No | 32 | 0.235 | 51 | 22 | 0.431 | 3 |
| H3F3B_ENST00000589599 | H3-3B | P84243 | Histone H3.3 | chr17 | GO:0006997 | Not Cancer Driver | No | 28 | 0.206 | 51 | 14 | 0.275 | 3 |
| HABP4 | HABP4 | Q5JVS0 | Intracellular hyaluronan-binding protein 4 | chr9 | GO:0006997 | Not Cancer Driver | No | 32 | 0.077 | 413 | 32 | 0.077 | 0 |
| HIPK2 | HIPK2 | Q9H2X6 | Homeodomain-interacting protein kinase 2 | chr7 | GO:0006997 | Not Cancer Driver | No | 154 | 0.129 | 686 | 96 | 0.14 | 0 |
| HMGB2 | HMGB2 | P26583 | High mobility group protein B2 | chr4 | GO:0006997 | Not Cancer Driver | No | 38 | 0.182 | 207 | 38 | 0.184 | 0 |
| KDM3A_ENST00000312912 | KDM3A | Q9Y4C1 | Lysine-specific demethylase 3A | chr2 | GO:0006997 | Not Cancer Driver | No | 136 | 0.103 | 461 | 47 | 0.102 | 0 |
| NDC1 | NDC1 | Q9BTX1 | Nucleoporin NDC1 | chr1 | GO:0006997 | Not Cancer Driver | No | 62 | 0.092 | 92 | 12 | 0.13 | 0 |
| NECTIN2 | NECTIN2 | Q92692 | Nectin-2 | chr19 | GO:0006997 | Not Cancer Driver | No | 63 | 0.117 | 296 | 29 | 0.098 | 0 |
| NOLC1_ENST00000605788 | NOLC1 | Q14978 | Nucleolar and coiled-body phosphoprotein 1 | chr10 | GO:0006997 | Not Cancer Driver | No | 74 | 0.106 | 662 | 69 | 0.104 | 0 |
| NUMA1 | NUMA1 | Q14980 | Nuclear mitotic apparatus protein 1 | chr11 | GO:0006997 | Census, Compendium | Yes | 234 | 0.111 | 1864 | 203 | 0.109 | 0 |
| NUP107 | NUP107 | P57740 | Nuclear pore complex protein Nup107 | chr12 | GO:0006997 | Not Cancer Driver | No | 127 | 0.137 | 183 | 26 | 0.142 | 5 |
| NUP133 | NUP133 | Q8WUM0 | Nuclear pore complex protein Nup133 | chr1 | GO:0006997 | Not Cancer Driver | No | 143 | 0.124 | 116 | 16 | 0.138 | 3 |
| NUP153_ENST00000262077 | NUP153 | P49790 | Nuclear pore complex protein Nup153 | chr6 | GO:0006997 | Not Cancer Driver | No | 180 | 0.122 | 1152 | 147 | 0.128 | 0 |
| NUP205 | NUP205 | Q92621 | Nuclear pore complex protein Nup205 | chr7 | GO:0006997 | Not Cancer Driver | No | 251 | 0.125 | 101 | 16 | 0.158 | 1 |
| NUP35 | NUP35 | Q8NFH5 | Nucleoporin NUP35 | chr2 | GO:0006997 | Not Cancer Driver | No | 39 | 0.12 | 209 | 27 | 0.129 | 0 |
| NUP54 | NUP54 | Q7Z3B4 | Nucleoporin p54 | chr4 | GO:0006997 | Not Cancer Driver | No | 42 | 0.083 | 233 | 25 | 0.107 | 0 |
| NUP93 | NUP93 | Q8N1F7 | Nuclear pore complex protein Nup93 | chr16 | GO:0006997 | Not Cancer Driver | No | 97 | 0.118 | 158 | 23 | 0.146 | 3 |
| NUP98_ENST00000359171 | NUP98 | P52948 | Nuclear pore complex protein Nup98-Nup96 | chr11 | GO:0006997 | Census | Yes | 227 | 0.125 | 1008 | 107 | 0.106 | 0 |
| PDCD6IP_ENST00000307296 | PDCD6IP | Q8WUM4 | Programmed cell death 6-interacting protein | chr3 | GO:0006997 | Not Cancer Driver | No | 85 | 0.098 | 272 | 22 | 0.081 | 0 |
| PITPNB_ENST00000335272 | PITPNB | P48739 | Phosphatidylinositol transfer protein beta isoform | chr22 | GO:0006997 | Not Cancer Driver | No | 26 | 0.096 | 69 | 2 | 0.029 | 0 |
| PLEC | PLEC | Q15149 | Plectin | chr8 | GO:0006997 | Not Cancer Driver | No | 677 | 0.145 | 2130 | 272 | 0.128 | 2 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0006997 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| POLR1B_ENST00000263331 | POLR1B | Q9H9Y6 | DNA-directed RNA polymerase I subunit RPA2 | chr2 | GO:0006997 | Not Cancer Driver | No | 120 | 0.106 | 69 | 10 | 0.145 | 2 |
| PRM2_ENST00000241808 | PRM2 | P04554 | Protamine-2 | chr16 | GO:0006997 | Not Cancer Driver | No | 23 | 0.225 | 102 | 23 | 0.225 | 0 |
| PYGO1 | PYGO1 | Q9Y3Y4 | Pygopus homolog 1 | chr15 | GO:0006997 | Not Cancer Driver | No | 71 | 0.169 | 362 | 60 | 0.166 | 0 |
| PYGO2 | PYGO2 | Q9BRQ0 | Pygopus homolog 2 | chr1 | GO:0006997 | Not Cancer Driver | No | 51 | 0.126 | 340 | 43 | 0.126 | 0 |
| RPS19_ENST00000600467 | RPS19 | P39019 | 40S ribosomal protein S19 | chr19 | GO:0006997 | Not Cancer Driver | No | 15 | 0.103 | 61 | 3 | 0.049 | 23 |
| RRN3 | RRN3 | Q9NYV6 | RNA polymerase I-specific transcription initiation factor RRN3 | chr16 | GO:0006997 | Not Cancer Driver | No | 66 | 0.101 | 115 | 15 | 0.13 | 0 |
| RTN4 | RTN4 | Q9NQC3 | Reticulon-4 | chr2 | GO:0006997 | Not Cancer Driver | No | 121 | 0.102 | 866 | 82 | 0.095 | 0 |
| SEH1L_ENST00000262124 | SEH1L | Q96EE3 | Nucleoporin SEH1 | chr18 | GO:0006997 | Not Cancer Driver | No | 40 | 0.111 | 71 | 11 | 0.155 | 0 |
| SERBP1 | SERBP1 | Q8NC51 | Plasminogen activator inhibitor 1 RNA-binding protein | chr1 | GO:0006997 | Not Cancer Driver | No | 53 | 0.13 | 408 | 53 | 0.13 | 0 |
| SF1_ENST00000377390 | SF1 | Q15637 | Splicing factor 1 | chr11 | GO:0006997 | Not Cancer Driver | No | 110 | 0.172 | 627 | 106 | 0.169 | 0 |
| SRPK2_ENST00000489828 | SRPK2 | P78362 | SRSF protein kinase 2 | chr7 | GO:0006997 | Not Cancer Driver | No | 78 | 0.113 | 343 | 46 | 0.134 | 0 |
| SUMO1_ENST00000392245 | SUMO1 | P63165 | Small ubiquitin-related modifier 1 | chr2 | GO:0006997 | Not Cancer Driver | No | 10 | 0.099 | 76 | 7 | 0.092 | 0 |
| SUN1 | SUN1 | O94901 | SUN domain-containing protein 1 | chr7 | GO:0006997 | Not Cancer Driver | No | 109 | 0.139 | 246 | 26 | 0.106 | 0 |
| SUN2_ENST00000405510 | SUN2 | Q9UH99 | SUN domain-containing protein 2 | chr22 | GO:0006997 | Not Cancer Driver | No | 74 | 0.103 | 214 | 18 | 0.084 | 0 |
| SYNE1 | SYNE1 | Q8NF91 | Nesprin-1 | chr6 | GO:0006997 | Not Cancer Driver | No | 1694 | 0.193 | 2530 | 530 | 0.209 | 2 |
| TBPL1 | TBPL1 | P62380 | TATA box-binding protein-like 1 | chr6 | GO:0006997 | Not Cancer Driver | No | 27 | 0.145 | 6 | 0 | 0.0 | 0 |
| TMEM170A | TMEM170A | Q8WVE7 | Transmembrane protein 170A | chr16 | GO:0006997 | Not Cancer Driver | No | 9 | 0.062 | 6 | 0 | 0.0 | 0 |
| TMF1 | TMF1 | P82094 | TATA element modulatory factor | chr3 | GO:0006997 | Not Cancer Driver | No | 109 | 0.1 | 946 | 99 | 0.105 | 0 |
| TNP1 | TNP1 | P09430 | Spermatid nuclear transition protein 1 | chr2 | GO:0006997 | Not Cancer Driver | No | 21 | 0.382 | 55 | 21 | 0.382 | 0 |
| TPR | TPR | P12270 | Nucleoprotein TPR | chr1 | GO:0006997 | Census | Yes | 311 | 0.132 | 1990 | 266 | 0.134 | 0 |
| USP36_ENST00000312010 | USP36 | Q9P275 | Ubiquitin carboxyl-terminal hydrolase 36 | chr17 | GO:0006997 | Not Cancer Driver | No | 151 | 0.134 | 718 | 91 | 0.127 | 0 |
| USP50 | USP50 | Q70EL3 | Inactive ubiquitin carboxyl-terminal hydrolase 50 | chr15 | GO:0006997 | Not Cancer Driver | No | 33 | 0.097 | 2 | 0 | 0.0 | 0 |
| USPL1 | USPL1 | Q5W0Q7 | SUMO-specific isopeptidase USPL1 | chr13 | GO:0006997 | Not Cancer Driver | No | 107 | 0.098 | 578 | 55 | 0.095 | 0 |
| VPS4A | VPS4A | Q9UN37 | Vacuolar protein sorting-associated protein 4A | chr16 | GO:0006997 | Not Cancer Driver | No | 48 | 0.11 | 167 | 17 | 0.102 | 4 |
| VPS4B | VPS4B | O75351 | Vacuolar protein sorting-associated protein 4B | chr18 | GO:0006997 | Not Cancer Driver | No | 52 | 0.117 | 195 | 22 | 0.113 | 0 |
| WBP2NL | WBP2NL | Q6ICG8 | Postacrosomal sheath WW domain-binding protein | chr22 | GO:0006997 | Not Cancer Driver | No | 46 | 0.149 | 153 | 27 | 0.176 | 0 |
| WDR73 | WDR73 | Q6P4I2 | WD repeat-containing protein 73 | chr15 | GO:0006997 | Not Cancer Driver | No | 29 | 0.077 | 86 | 7 | 0.081 | 0 |
| WEE2 | WEE2 | P0C1S8 | Wee1-like protein kinase 2 | chr7 | GO:0006997 | Not Cancer Driver | No | 104 | 0.183 | 345 | 65 | 0.188 | 1 |
| WRAP53 | WRAP53 | Q9BUR4 | Telomerase Cajal body protein 1 | chr17 | GO:0006997 | Not Cancer Driver | No | 66 | 0.12 | 232 | 29 | 0.125 | 4 |
| ZPR1 | ZPR1 | O75312 | Zinc finger protein ZPR1 | chr11 | GO:0006997 | Not Cancer Driver | No | 38 | 0.083 | 291 | 27 | 0.093 | 0 |