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Total number of protein in "GO:0006974" GO term:  355

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0006974 Census, Compendium Yes 139 0.123 604 73 0.121 2
ACD_ENST00000620761 ACD Q96AP0 Adrenocortical dysplasia protein homolog chr16 GO:0006974 Not Cancer Driver No 49 0.107 256 34 0.133 1
ACER2 ACER2 Q5QJU3 Alkaline ceramidase 2 chr9 GO:0006974 Not Cancer Driver No 27 0.098 0 0 0.0 0
ACTR5 ACTR5 Q9H9F9 Actin-related protein 5 chr20 GO:0006974 Not Cancer Driver No 63 0.104 163 23 0.141 0
AKTIP_ENST00000570004 AKTIP Q9H8T0 AKT-interacting protein chr16 GO:0006974 Not Cancer Driver No 33 0.113 95 10 0.105 0
ALKBH7 ALKBH7 Q9BT30 Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial chr19 GO:0006974 Not Cancer Driver No 21 0.095 28 1 0.036 0
ALKBH8_ENST00000389568 ALKBH8 Q96BT7 Alkylated DNA repair protein alkB homolog 8 chr11 GO:0006974 Not Cancer Driver No 50 0.075 189 12 0.063 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 GO:0006974 Not Cancer Driver No 105 0.148 399 58 0.145 0
APC APC P25054 Adenomatous polyposis coli protein chr5 GO:0006974 Census, Compendium Yes 412 0.145 2406 345 0.143 22
APEX1_ENST00000555414 APEX1 P27695 DNA-(apurinic or apyrimidinic site) endonuclease chr14 GO:0006974 Not Cancer Driver No 34 0.107 103 14 0.136 0
APLF APLF Q8IW19 Aprataxin and PNK-like factor chr2 GO:0006974 Not Cancer Driver No 64 0.125 407 57 0.14 0
APTX_ENST00000379819 APTX Q7Z2E3 Aprataxin chr9 GO:0006974 Not Cancer Driver No 36 0.101 101 6 0.059 9
ARMT1 ARMT1 Q9H993 Damage-control phosphatase ARMT1 chr6 GO:0006974 Not Cancer Driver No 53 0.12 1 0 0.0 0
ASH2L ASH2L Q9UBL3 Set1/Ash2 histone methyltransferase complex subunit ASH2 chr8 GO:0006974 Not Cancer Driver No 95 0.151 293 39 0.133 0
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0006974 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATMIN ATMIN O43313 ATM interactor chr16 GO:0006974 Not Cancer Driver No 85 0.103 466 40 0.086 0
ATM_ENST00000452508 ATM Q13315 Serine-protein kinase ATM chr11 GO:0006974 Census, Compendium Yes 469 0.153 225 39 0.173 41
ATR ATR Q13535 Serine/threonine-protein kinase ATR chr3 GO:0006974 Census, Compendium Yes 338 0.128 106 14 0.132 1
ATRX ATRX P46100 Transcriptional regulator ATRX chrX GO:0006974 Census, Compendium Yes 487 0.195 1672 301 0.18 33
BABAM2_ENST00000342045 BABAM2 Q9NXR7 BRISC and BRCA1-A complex member 2 chr2 GO:0006974 Not Cancer Driver No 52 0.136 0 0 0.0 0
BARD1 BARD1 Q99728 BRCA1-associated RING domain protein 1 chr2 GO:0006974 Census Yes 96 0.124 384 49 0.128 0
BATF BATF Q16520 Basic leucine zipper transcriptional factor ATF-like chr14 GO:0006974 Not Cancer Driver No 28 0.224 119 25 0.21 0
BAZ1B_ENST00000404251 BAZ1B Q9UIG0 Tyrosine-protein kinase BAZ1B chr7 GO:0006974 Not Cancer Driver No 153 0.103 840 87 0.104 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0006974 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL3 BCL3 P20749 B-cell lymphoma 3 protein chr19 GO:0006974 Census Yes 44 0.097 259 23 0.089 0
BCL6_ENST00000232014 BCL6 P41182 B-cell lymphoma 6 protein chr3 GO:0006974 Census, Compendium Yes 134 0.19 328 67 0.204 0
BLK BLK P51451 Tyrosine-protein kinase Blk chr8 GO:0006974 Not Cancer Driver No 94 0.186 75 21 0.28 0
BLM BLM P54132 Bloom syndrome protein chr15 GO:0006974 Census Yes 153 0.108 667 70 0.105 8
BOD1L1 BOD1L1 Q8NFC6 Biorientation of chromosomes in cell division protein 1-like 1 chr4 GO:0006974 Not Cancer Driver No 387 0.127 3023 384 0.127 0
BRAT1 BRAT1 Q6PJG6 BRCA1-associated ATM activator 1 chr7 GO:0006974 Not Cancer Driver No 112 0.136 101 13 0.129 0
BRCA2_ENST00000544455 BRCA2 P51587 Breast cancer type 2 susceptibility protein chr13 GO:0006974 Census, Compendium Yes 457 0.134 1542 225 0.146 46
BRD4 BRD4 O60885 Bromodomain-containing protein 4 chr19 GO:0006974 Census, Compendium Yes 193 0.142 1182 172 0.146 0
BRIP1 BRIP1 Q9BX63 Fanconi anemia group J protein chr17 GO:0006974 Census Yes 174 0.139 397 59 0.149 6
BRSK1 BRSK1 Q8TDC3 Serine/threonine-protein kinase BRSK1 chr19 GO:0006974 Not Cancer Driver No 131 0.168 459 78 0.17 0
BTG2 BTG2 P78543 Protein BTG2 chr1 GO:0006974 Census Yes 32 0.203 7 2 0.286 0
C17orf53 HROB Q8N3J3 Homologous recombination OB-fold protein chr17 GO:0006974 Not Cancer Driver No 76 0.117 528 61 0.116 0
C19orf57_ENST00000586783 BRME1 Q0VDD7 Break repair meiotic recombinase recruitment factor 1 chr19 GO:0006974 Not Cancer Driver No 91 0.136 632 88 0.139 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0006974 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0006974 Census Yes 32 0.116 62 5 0.081 0
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0006974 Census Yes 49 0.118 71 7 0.099 0
CBL CBL P22681 E3 ubiquitin-protein ligase CBL chr11 GO:0006974 Census, Compendium Yes 115 0.127 512 56 0.109 4
CBX1_ENST00000225603 CBX1 P83916 Chromobox protein homolog 1 chr17 GO:0006974 Not Cancer Driver No 31 0.168 154 25 0.162 0
CBX3_ENST00000396386 CBX3 Q13185 Chromobox protein homolog 3 chr7 GO:0006974 Not Cancer Driver No 23 0.126 119 18 0.151 0
CBX5 CBX5 P45973 Chromobox protein homolog 5 chr12 GO:0006974 Not Cancer Driver No 21 0.11 116 12 0.103 0
CCAR2 CCAR2 Q8N163 Cell cycle and apoptosis regulator protein 2 chr8 GO:0006974 Not Cancer Driver No 102 0.111 528 62 0.117 0
CCDC13 CCDC13 Q8IYE1 Coiled-coil domain-containing protein 13 chr3 GO:0006974 Not Cancer Driver No 114 0.159 580 95 0.164 0
CCND1 CCND1 P24385 G1/S-specific cyclin-D1 chr11 GO:0006974 Census, Compendium Yes 55 0.186 31 25 0.806 0
CCNK CCNK O75909 Cyclin-K chr14 GO:0006974 Not Cancer Driver No 39 0.067 347 15 0.043 1
CDK2 CDK2 P24941 Cyclin-dependent kinase 2 chr12 GO:0006974 Not Cancer Driver No 24 0.081 0 0 0.0 0
CDK3_ENST00000448471 CDK3 Q00526 Cyclin-dependent kinase 3 chr17 GO:0006974 Not Cancer Driver No 40 0.131 17 2 0.118 0
CDKN1A_ENST00000373711 CDKN1A P38936 Cyclin-dependent kinase inhibitor 1 chr6 GO:0006974 Census, Compendium Yes 48 0.293 121 30 0.248 0
CDKN1B CDKN1B P46527 Cyclin-dependent kinase inhibitor 1B chr12 GO:0006974 Census, Compendium Yes 19 0.096 198 19 0.096 0
CDKN2AIP CDKN2AIP Q9NXV6 CDKN2A-interacting protein chr4 GO:0006974 Not Cancer Driver No 53 0.091 352 38 0.108 0
CENPS CENPS Q8N2Z9 Centromere protein S chr1 GO:0006974 Not Cancer Driver No 16 0.116 65 7 0.108 0
CFAP410_ENST00000339818 CFAP410 O43822 Cilia- and flagella-associated protein 410 chr21 GO:0006974 Not Cancer Driver No 17 0.066 134 10 0.075 7
CGAS CGAS Q8N884 Cyclic GMP-AMP synthase chr6 GO:0006974 Not Cancer Driver No 50 0.096 173 7 0.04 0
CHCHD6 CHCHD6 Q9BRQ6 MICOS complex subunit MIC25 chr3 GO:0006974 Not Cancer Driver No 27 0.115 194 24 0.124 0
CHD1L CHD1L Q86WJ1 Chromodomain-helicase-DNA-binding protein 1-like chr1 GO:0006974 Not Cancer Driver No 98 0.109 225 30 0.133 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0006974 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHEK2_ENST00000405598 CHEK2 O96017 Serine/threonine-protein kinase Chk2 chr22 GO:0006974 Census, Compendium Yes 335 0.617 157 130 0.828 13
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0006974 Not Cancer Driver No 24 0.126 6 1 0.167 0
CRADD_ENST00000332896 CRADD P78560 Death domain-containing protein CRADD chr12 GO:0006974 Not Cancer Driver No 35 0.176 45 5 0.111 1
CRY1 CRY1 Q16526 Cryptochrome-1 chr12 GO:0006974 Not Cancer Driver No 76 0.13 91 5 0.055 0
CRY2_ENST00000616080 CRY2 Q49AN0 Cryptochrome-2 chr11 GO:0006974 Not Cancer Driver No 72 0.121 100 12 0.12 0
CTC1 CTC1 Q2NKJ3 CST complex subunit CTC1 chr17 GO:0006974 Not Cancer Driver No 142 0.117 103 8 0.078 9
CTLA4 CTLA4 P16410 Cytotoxic T-lymphocyte protein 4 chr2 GO:0006974 Not Cancer Driver No 37 0.166 3 0 0.0 1
CUL4A CUL4A Q13619 Cullin-4A chr13 GO:0006974 Not Cancer Driver No 64 0.084 102 2 0.02 0
CUL4B CUL4B Q13620 Cullin-4B chrX GO:0006974 Not Cancer Driver No 138 0.151 207 38 0.184 2
DCLRE1A DCLRE1A Q6PJP8 DNA cross-link repair 1A protein chr10 GO:0006974 Not Cancer Driver No 92 0.088 514 45 0.088 0
DCLRE1B DCLRE1B Q9H816 5' exonuclease Apollo chr1 GO:0006974 Not Cancer Driver No 65 0.122 127 17 0.134 0
DCLRE1C DCLRE1C Q96SD1 Protein artemis chr10 GO:0006974 Not Cancer Driver No 76 0.11 277 26 0.094 3
DCUN1D5 DCUN1D5 Q9BTE7 DCN1-like protein 5 chr11 GO:0006974 Not Cancer Driver No 18 0.076 7 0 0.0 0
DDB1 DDB1 Q16531 DNA damage-binding protein 1 chr11 GO:0006974 Not Cancer Driver No 126 0.111 50 8 0.16 4
DDB2 DDB2 Q92466 DNA damage-binding protein 2 chr11 GO:0006974 Census, Compendium Yes 45 0.105 70 5 0.071 2
DDIT3_ENST00000623876 DDIT3 P35638 DNA damage-inducible transcript 3 protein chr12 GO:0006974 Census Yes 29 0.172 160 27 0.169 0
DDX11 DDX11 Q96FC9 ATP-dependent DNA helicase DDX11 chr12 GO:0006974 Not Cancer Driver No 154 0.159 280 55 0.196 1
DNA2 DNA2 P51530 DNA replication ATP-dependent helicase/nuclease DNA2 chr10 GO:0006974 Not Cancer Driver No 120 0.113 52 8 0.154 3
DTL DTL Q9NZJ0 Denticleless protein homolog chr1 GO:0006974 Not Cancer Driver No 73 0.1 331 49 0.148 0
DTX3L DTX3L Q8TDB6 E3 ubiquitin-protein ligase DTX3L chr3 GO:0006974 Not Cancer Driver No 86 0.116 260 24 0.092 0
DYRK2 DYRK2 Q92630 Dual specificity tyrosine-phosphorylation-regulated kinase 2 chr12 GO:0006974 Not Cancer Driver No 77 0.128 294 39 0.133 0
E2F7 E2F7 Q96AV8 Transcription factor E2F7 chr12 GO:0006974 Not Cancer Driver No 122 0.134 554 70 0.126 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 GO:0006974 Not Cancer Driver No 33 0.138 13 0 0.0 0
ERCC1_ENST00000589165 ERCC1 P07992 DNA excision repair protein ERCC-1 chr19 GO:0006974 Not Cancer Driver No 42 0.141 105 14 0.133 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0006974 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0006974 Census, Compendium Yes 92 0.118 208 22 0.106 2
ERCC4 ERCC4 Q92889 DNA repair endonuclease XPF chr16 GO:0006974 Census Yes 120 0.131 225 27 0.12 15
ERCC5 ERCC5 P28715 DNA excision repair protein ERCC-5 chr13 GO:0006974 Census Yes 175 0.148 816 121 0.148 6
ERCC6 ERCC6 Q03468 DNA excision repair protein ERCC-6 chr10 GO:0006974 Not Cancer Driver No 211 0.141 829 117 0.141 9
ERCC8 ERCC8 Q13216 DNA excision repair protein ERCC-8 chr5 GO:0006974 Not Cancer Driver No 25 0.063 53 8 0.151 7
ETAA1 ETAA1 Q9NY74 Ewing's tumor-associated antigen 1 chr2 GO:0006974 Not Cancer Driver No 101 0.109 735 75 0.102 0
FAAP20_ENST00000378546 FAAP20 Q6NZ36 Fanconi anemia core complex-associated protein 20 chr1 GO:0006974 Not Cancer Driver No 23 0.128 137 19 0.139 0
FAM111A FAM111A Q96PZ2 Serine protease FAM111A chr11 GO:0006974 Not Cancer Driver No 78 0.128 169 23 0.136 5
FANCB FANCB Q8NB91 Fanconi anemia group B protein chrX GO:0006974 Not Cancer Driver No 109 0.127 24 5 0.208 0
FANCD2_ENST00000383807 FANCD2 Q9BXW9 Fanconi anemia group D2 protein chr3 GO:0006974 Census, Compendium Yes 176 0.121 181 14 0.077 3
FANCF FANCF Q9NPI8 Fanconi anemia group F protein chr11 GO:0006974 Census, Compendium Yes 32 0.086 51 4 0.078 0
FANCG FANCG O15287 Fanconi anemia group G protein chr9 GO:0006974 Census Yes 64 0.103 48 3 0.062 1
FANCL_ENST00000233741 FANCL Q9NW38 E3 ubiquitin-protein ligase FANCL chr2 GO:0006974 Not Cancer Driver No 47 0.125 11 0 0.0 0
FANCM FANCM Q8IYD8 Fanconi anemia group M protein chr14 GO:0006974 Not Cancer Driver No 268 0.131 898 128 0.143 0
FBH1_ENST00000362091 FBH1 Q8NFZ0 F-box DNA helicase 1 chr10 GO:0006974 Not Cancer Driver No 139 0.133 192 32 0.167 0
FBXO31 FBXO31 Q5XUX0 F-box only protein 31 chr16 GO:0006974 Not Cancer Driver No 72 0.134 231 30 0.13 0
FBXO45 FBXO45 P0C2W1 F-box/SPRY domain-containing protein 1 chr3 GO:0006974 Not Cancer Driver No 28 0.098 10 0 0.0 0
FMN2 FMN2 Q9NZ56 Formin-2 chr1 GO:0006974 Not Cancer Driver No 614 0.357 1322 475 0.359 0
FMR1 FMR1 Q06787 Synaptic functional regulator FMR1 chrX GO:0006974 Not Cancer Driver No 124 0.196 327 70 0.214 3
FOXM1_ENST00000359843 FOXM1 Q08050 Forkhead box protein M1 chr12 GO:0006974 Not Cancer Driver No 97 0.127 601 73 0.121 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0006974 Census, Compendium Yes 81 0.124 584 75 0.128 0
FOXO3 FOXO3 O43524 Forkhead box protein O3 chr6 GO:0006974 Census, Compendium Yes 70 0.104 595 68 0.114 0
FOXP1_ENST00000318789 FOXP1 Q9H334 Forkhead box protein P1 chr3 GO:0006974 Census, Compendium Yes 109 0.161 448 71 0.158 3
GCNA GCNA Q96QF7 Germ cell nuclear acidic protein chrX GO:0006974 Not Cancer Driver No 155 0.224 513 122 0.238 0
GIGYF2_ENST00000409547 GIGYF2 Q6Y7W6 GRB10-interacting GYF protein 2 chr2 GO:0006974 Not Cancer Driver No 176 0.135 1096 158 0.144 6
GML GML Q99445 Glycosyl-phosphatidylinositol-anchored molecule-like protein chr8 GO:0006974 Not Cancer Driver No 49 0.31 12 6 0.5 0
GNL1 GNL1 P36915 Guanine nucleotide-binding protein-like 1 chr6 GO:0006974 Not Cancer Driver No 62 0.102 268 24 0.09 0
GTSE1 GTSE1 Q9NYZ3 G2 and S phase-expressed protein 1 chr22 GO:0006974 Not Cancer Driver No 91 0.126 660 85 0.129 0
H2AFX H2AX P16104 Histone H2AX chr11 GO:0006974 Not Cancer Driver No 20 0.14 68 10 0.147 0
HELB HELB Q8NG08 DNA helicase B chr12 GO:0006974 Not Cancer Driver No 140 0.129 300 38 0.127 0
HERC2 HERC2 O95714 E3 ubiquitin-protein ligase HERC2 chr15 GO:0006974 Compendium Yes 718 0.149 971 150 0.154 1
HIPK2 HIPK2 Q9H2X6 Homeodomain-interacting protein kinase 2 chr7 GO:0006974 Not Cancer Driver No 154 0.129 686 96 0.14 0
HIST3H2A H2AW Q7L7L0 Histone H2A type 3 chr1 GO:0006974 Not Cancer Driver No 21 0.162 61 10 0.164 0
HMCES_ENST00000502878 HMCES Q96FZ2 Abasic site processing protein HMCES chr3 GO:0006974 Not Cancer Driver No 37 0.105 131 16 0.122 0
HPF1 HPF1 Q9NWY4 Histone PARylation factor 1 chr4 GO:0006974 Not Cancer Driver No 32 0.092 23 0 0.0 0
HSF2BP HSF2BP O75031 Heat shock factor 2-binding protein chr21 GO:0006974 Not Cancer Driver No 52 0.156 23 3 0.13 1
HUS1 HUS1 O60921 Checkpoint protein HUS1 chr7 GO:0006974 Not Cancer Driver No 25 0.089 17 2 0.118 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0006974 Not Cancer Driver No 6 0.014 301 6 0.02 22
IMMP2L_ENST00000452895 IMMP2L Q96T52 Mitochondrial inner membrane protease subunit 2 chr7 GO:0006974 Not Cancer Driver No 36 0.206 29 7 0.241 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0006974 Not Cancer Driver No 31 0.124 108 15 0.139 0
INIP INIP Q9NRY2 SOSS complex subunit C chr9 GO:0006974 Not Cancer Driver No 25 0.24 79 16 0.203 0
INO80_ENST00000401393 INO80 Q9ULG1 Chromatin-remodeling ATPase INO80 chr15 GO:0006974 Compendium Yes 173 0.111 682 76 0.111 0
INTS3_ENST00000435409 INTS3 Q68E01 Integrator complex subunit 3 chr1 GO:0006974 Not Cancer Driver No 125 0.12 213 25 0.117 0
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0006974 Not Cancer Driver No 36 0.084 204 21 0.103 1
IRF7_ENST00000397574 IRF7 Q92985 Interferon regulatory factor 7 chr11 GO:0006974 Not Cancer Driver No 43 0.085 253 19 0.075 1
KAT5_ENST00000377046 KAT5 Q92993 Histone acetyltransferase KAT5 chr11 GO:0006974 Not Cancer Driver No 65 0.127 173 21 0.121 3
KIN KIN O60870 DNA/RNA-binding protein KIN17 chr10 GO:0006974 Not Cancer Driver No 52 0.132 137 13 0.095 0
LIG3 LIG3 P49916 DNA ligase 3 chr17 GO:0006974 Not Cancer Driver No 125 0.124 280 36 0.129 0
LIG4 LIG4 P49917 DNA ligase 4 chr13 GO:0006974 Not Cancer Driver No 134 0.147 63 10 0.159 2
LYN LYN P07948 Tyrosine-protein kinase Lyn chr8 GO:0006974 Census Yes 95 0.186 84 12 0.143 0
MACROD1 MACROD1 Q9BQ69 ADP-ribose glycohydrolase MACROD1 chr11 GO:0006974 Not Cancer Driver No 24 0.074 45 1 0.022 0
MACROD2 MACROD2 A1Z1Q3 ADP-ribose glycohydrolase MACROD2 chr20 GO:0006974 Not Cancer Driver No 106 0.249 231 60 0.26 0
MAD2L2 MAD2L2 Q9UI95 Mitotic spindle assembly checkpoint protein MAD2B chr1 GO:0006974 Not Cancer Driver No 22 0.104 0 0 0.0 1
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0006974 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAPK12 MAPK12 P53778 Mitogen-activated protein kinase 12 chr22 GO:0006974 Not Cancer Driver No 31 0.084 63 5 0.079 0
MAPK15 MAPK15 Q8TD08 Mitogen-activated protein kinase 15 chr8 GO:0006974 Not Cancer Driver No 81 0.149 235 37 0.157 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0006974 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0006974 Not Cancer Driver No 38 0.1 49 5 0.102 0
MAPKAPK2 MAPKAPK2 P49137 MAP kinase-activated protein kinase 2 chr1 GO:0006974 Not Cancer Driver No 43 0.107 92 5 0.054 0
MASTL MASTL Q96GX5 Serine/threonine-protein kinase greatwall chr10 GO:0006974 Not Cancer Driver No 90 0.102 389 44 0.113 0
MC1R_ENST00000639847 MC1R Q01726 Melanocyte-stimulating hormone receptor chr16 GO:0006974 Not Cancer Driver No 39 0.123 0 0 0.0 5
MCM10 MCM10 Q7L590 Protein MCM10 homolog chr10 GO:0006974 Not Cancer Driver No 152 0.174 535 102 0.191 1
MCM7 MCM7 P33993 DNA replication licensing factor MCM7 chr7 GO:0006974 Not Cancer Driver No 101 0.14 128 22 0.172 0
MCM8_ENST00000378896 MCM8 Q9UJA3 DNA helicase MCM8 chr20 GO:0006974 Not Cancer Driver No 94 0.112 188 19 0.101 1
MCM9_ENST00000619706 MCM9 Q9NXL9 DNA helicase MCM9 chr6 GO:0006974 Not Cancer Driver No 56 0.049 523 13 0.025 0
MCTS1_ENST00000371317 MCTS1 Q9ULC4 Malignant T-cell-amplified sequence 1 chrX GO:0006974 Not Cancer Driver No 34 0.188 0 0 0.0 0
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0006974 Census, Compendium Yes 56 0.114 297 37 0.125 0
MDM4 MDM4 O15151 Protein Mdm4 chr1 GO:0006974 Census, Compendium Yes 57 0.116 202 26 0.129 1
MEN1 MEN1 O00255 Menin chr11 GO:0006974 Census, Compendium Yes 73 0.119 228 15 0.066 90
METTL3 METTL3 Q86U44 N6-adenosine-methyltransferase catalytic subunit chr14 GO:0006974 Not Cancer Driver No 74 0.128 274 29 0.106 0
MGME1 MGME1 Q9BQP7 Mitochondrial genome maintenance exonuclease 1 chr20 GO:0006974 Not Cancer Driver No 33 0.096 95 7 0.074 1
MIF MIF P14174 Macrophage migration inhibitory factor chr22 GO:0006974 Not Cancer Driver No 4 0.035 0 0 0.0 0
MMS19 MMS19 Q96T76 MMS19 nucleotide excision repair protein homolog chr10 GO:0006974 Not Cancer Driver No 73 0.071 11 0 0.0 0
MNDA MNDA P41218 Myeloid cell nuclear differentiation antigen chr1 GO:0006974 Not Cancer Driver No 180 0.442 172 76 0.442 0
MORC2 MORC2 Q9Y6X9 ATPase MORC2 chr22 GO:0006974 Not Cancer Driver No 125 0.121 523 69 0.132 16
MRE11 MRE11 P49959 Double-strand break repair protein MRE11 chr11 GO:0006974 Not Cancer Driver No 84 0.119 292 35 0.12 1
MRNIP MRNIP Q6NTE8 MRN complex-interacting protein chr5 GO:0006974 Not Cancer Driver No 44 0.128 268 35 0.131 0
MSH6 MSH6 P52701 DNA mismatch repair protein Msh6 chr2 GO:0006974 Census Yes 154 0.113 386 41 0.106 6
MTREX MTREX P42285 Exosome RNA helicase MTR4 chr5 GO:0006974 Not Cancer Driver No 117 0.112 160 15 0.094 0
MUC1_ENST00000611571 MUC1 P15941 Mucin-1 chr1 GO:0006974 Census Yes 40 0.032 1050 19 0.018 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0006974 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYO6 MYO6 Q9UM54 Unconventional myosin-VI chr6 GO:0006974 Not Cancer Driver No 176 0.136 342 41 0.12 3
NABP1 NABP1 Q96AH0 SOSS complex subunit B2 chr2 GO:0006974 Not Cancer Driver No 25 0.123 102 11 0.108 0
NABP2_ENST00000341463 NABP2 Q9BQ15 SOSS complex subunit B1 chr12 GO:0006974 Not Cancer Driver No 25 0.118 125 17 0.136 0
NBN NBN O60934 Nibrin chr8 GO:0006974 Census Yes 90 0.119 417 54 0.129 1
NCOA6 NCOA6 Q14686 Nuclear receptor coactivator 6 chr20 GO:0006974 Not Cancer Driver No 242 0.117 1941 219 0.113 0
NDRG1 NDRG1 Q92597 Protein NDRG1 chr8 GO:0006974 Census Yes 66 0.168 140 22 0.157 0
NEDD4 NEDD4 P46934 E3 ubiquitin-protein ligase NEDD4 chr15 GO:0006974 Not Cancer Driver No 150 0.114 711 79 0.111 0
NEK4 NEK4 P51957 Serine/threonine-protein kinase Nek4 chr3 GO:0006974 Not Cancer Driver No 78 0.093 492 49 0.1 0
NFATC2 NFATC2 Q13469 Nuclear factor of activated T-cells, cytoplasmic 2 chr20 GO:0006974 Census, Compendium Yes 194 0.21 722 162 0.224 0
NIPBL NIPBL Q6KC79 Nipped-B-like protein chr5 GO:0006974 Compendium Yes 353 0.126 1528 184 0.12 37
NOP53 NOP53 Q9NZM5 Ribosome biogenesis protein NOP53 chr19 GO:0006974 Not Cancer Driver No 59 0.123 391 41 0.105 0
NPAS2 NPAS2 Q99743 Neuronal PAS domain-containing protein 2 chr2 GO:0006974 Not Cancer Driver No 114 0.138 465 65 0.14 0
NRDE2 NRDE2 Q9H7Z3 Nuclear exosome regulator NRDE2 chr14 GO:0006974 Not Cancer Driver No 135 0.116 373 50 0.134 0
NUAK1 NUAK1 O60285 NUAK family SNF1-like kinase 1 chr12 GO:0006974 Not Cancer Driver No 142 0.215 357 77 0.216 0
NUPR2 NUPR2 A6NF83 Nuclear protein 2 chr7 GO:0006974 Not Cancer Driver No 3 0.031 76 3 0.039 0
OARD1 OARD1 Q9Y530 ADP-ribose glycohydrolase OARD1 chr6 GO:0006974 Not Cancer Driver No 14 0.092 13 0 0.0 0
OGG1_ENST00000344629 OGG1 O15527 N-glycosylase/DNA lyase chr3 GO:0006974 Not Cancer Driver No 37 0.107 71 12 0.169 0
OTUB1_ENST00000428192 OTUB1 Q96FW1 Ubiquitin thioesterase OTUB1 chr11 GO:0006974 Not Cancer Driver No 31 0.114 33 2 0.061 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0006974 Not Cancer Driver No 57 0.105 299 30 0.1 2
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0006974 Not Cancer Driver No 119 0.117 320 34 0.106 0
PARP4 PARP4 Q9UKK3 Protein mono-ADP-ribosyltransferase PARP4 chr13 GO:0006974 Compendium Yes 218 0.126 325 40 0.123 0
PAXIP1 PAXIP1 Q6ZW49 PAX-interacting protein 1 chr7 GO:0006974 Not Cancer Driver No 120 0.112 461 39 0.085 0
PAXX PAXX Q9BUH6 Protein PAXX chr9 GO:0006974 Not Cancer Driver No 22 0.108 121 17 0.14 0
PCLAF PCLAF Q15004 PCNA-associated factor chr15 GO:0006974 Not Cancer Driver No 20 0.18 111 20 0.18 0
PHF1 PHF1 O43189 PHD finger protein 1 chr6 GO:0006974 Not Cancer Driver No 62 0.109 277 29 0.105 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:0006974 Not Cancer Driver No 93 0.102 137 14 0.102 0
PLK2 PLK2 Q9NYY3 Serine/threonine-protein kinase PLK2 chr5 GO:0006974 Not Cancer Driver No 92 0.134 178 21 0.118 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0006974 Not Cancer Driver No 75 0.116 202 15 0.074 0
PLK5 PLK5 Q496M5 Inactive serine/threonine-protein kinase PLK5 chr19 GO:0006974 Not Cancer Driver No 8 0.024 215 4 0.019 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0006974 Not Cancer Driver No 2 0.037 23 1 0.043 0
PML PML P29590 Protein PML chr15 GO:0006974 Census, Compendium Yes 112 0.127 312 34 0.109 0
POLB POLB P06746 DNA polymerase beta chr8 GO:0006974 Not Cancer Driver No 43 0.128 87 11 0.126 0
POLD1_ENST00000440232 POLD1 P28340 DNA polymerase delta catalytic subunit chr19 GO:0006974 Census, Compendium Yes 179 0.162 214 31 0.145 2
POLD2_ENST00000452185 POLD2 P49005 DNA polymerase delta subunit 2 chr7 GO:0006974 Not Cancer Driver No 49 0.104 65 3 0.046 0
POLD3 POLD3 Q15054 DNA polymerase delta subunit 3 chr11 GO:0006974 Not Cancer Driver No 51 0.109 326 39 0.12 0
POLDIP2 POLDIP2 Q9Y2S7 Polymerase delta-interacting protein 2 chr17 GO:0006974 Not Cancer Driver No 36 0.098 94 13 0.138 0
POLE POLE Q07864 DNA polymerase epsilon catalytic subunit A chr12 GO:0006974 Census, Compendium Yes 409 0.179 239 44 0.184 3
POLE2 POLE2 P56282 DNA polymerase epsilon subunit 2 chr14 GO:0006974 Not Cancer Driver No 53 0.101 32 2 0.062 0
POLE3 POLE3 Q9NRF9 DNA polymerase epsilon subunit 3 chr9 GO:0006974 Not Cancer Driver No 11 0.075 117 9 0.077 0
POLH POLH Q9Y253 DNA polymerase eta chr6 GO:0006974 Not Cancer Driver No 72 0.101 291 20 0.069 10
POLI POLI Q9UNA4 DNA polymerase iota chr18 GO:0006974 Not Cancer Driver No 82 0.111 300 32 0.107 0
POLK POLK Q9UBT6 DNA polymerase kappa chr5 GO:0006974 Not Cancer Driver No 97 0.111 293 36 0.123 0
POLQ POLQ O75417 DNA polymerase theta chr3 GO:0006974 Census, Compendium Yes 364 0.141 949 135 0.142 0
POLR2I POLR2I P36954 DNA-directed RNA polymerase II subunit RPB9 chr19 GO:0006974 Not Cancer Driver No 21 0.168 22 5 0.227 0
PPM1D PPM1D O15297 Protein phosphatase 1D chr17 GO:0006974 Census, Compendium Yes 54 0.089 370 32 0.086 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0006974 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP4R3A_ENST00000554943 PPP4R3A Q6IN85 Serine/threonine-protein phosphatase 4 regulatory subunit 3A chr14 GO:0006974 Not Cancer Driver No 89 0.107 255 29 0.114 0
PPP4R3B PPP4R3B Q5MIZ7 Serine/threonine-protein phosphatase 4 regulatory subunit 3B chr2 GO:0006974 Not Cancer Driver No 100 0.118 240 33 0.138 0
PPP4R3C PPP4R3C Q6ZMV5 Protein PPP4R3C chrX GO:0006974 Not Cancer Driver No 1 0.001 184 0 0.0 0
PRAP1 PRAP1 Q96NZ9 Proline-rich acidic protein 1 chr10 GO:0006974 Not Cancer Driver No 14 0.093 124 13 0.105 0
PRDM9 PRDM9 Q9NQV7 Histone-lysine N-methyltransferase PRDM9 chr5 GO:0006974 Not Cancer Driver No 494 0.553 372 201 0.54 0
PRIMPOL_ENST00000503752 PRIMPOL Q96LW4 DNA-directed primase/polymerase protein chr4 GO:0006974 Not Cancer Driver No 50 0.089 92 7 0.076 0
PRKDC PRKDC P78527 DNA-dependent protein kinase catalytic subunit chr8 GO:0006974 Not Cancer Driver No 538 0.13 421 61 0.145 2
PSEN1 PSEN1 P49768 Presenilin-1 chr14 GO:0006974 Not Cancer Driver No 61 0.131 134 21 0.157 96
PSME4 PSME4 Q14997 Proteasome activator complex subunit 4 chr2 GO:0006974 Not Cancer Driver No 214 0.116 134 12 0.09 0
RAD1 RAD1 O60671 Cell cycle checkpoint protein RAD1 chr5 GO:0006974 Not Cancer Driver No 29 0.103 4 1 0.25 0
RAD17 RAD17 O75943 Cell cycle checkpoint protein RAD17 chr5 GO:0006974 Census Yes 78 0.115 207 19 0.092 0
RAD18 RAD18 Q9NS91 E3 ubiquitin-protein ligase RAD18 chr3 GO:0006974 Not Cancer Driver No 59 0.119 328 43 0.131 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0006974 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAD21L1 RAD21L1 Q9H4I0 Double-strand-break repair protein rad21-like protein 1 chr20 GO:0006974 Not Cancer Driver No 37 0.067 186 5 0.027 0
RAD50 RAD50 Q92878 DNA repair protein RAD50 chr5 GO:0006974 Not Cancer Driver No 157 0.12 730 84 0.115 0
RAD51AP1 RAD51AP1 Q96B01 RAD51-associated protein 1 chr12 GO:0006974 Not Cancer Driver No 46 0.131 335 43 0.128 0
RAD51_ENST00000267868 RAD51 Q06609 DNA repair protein RAD51 homolog 1 chr15 GO:0006974 Not Cancer Driver No 42 0.124 47 5 0.106 3
RAD52 RAD52 P43351 DNA repair protein RAD52 homolog chr12 GO:0006974 Not Cancer Driver No 41 0.098 251 30 0.12 0
RAD54L_ENST00000442598 RAD54L Q92698 DNA repair and recombination protein RAD54-like chr1 GO:0006974 Not Cancer Driver No 79 0.106 124 13 0.105 0
RAD9A RAD9A Q99638 Cell cycle checkpoint control protein RAD9A chr11 GO:0006974 Not Cancer Driver No 34 0.087 135 7 0.052 0
RBBP5 RBBP5 Q15291 Retinoblastoma-binding protein 5 chr1 GO:0006974 Not Cancer Driver No 57 0.106 218 19 0.087 0
RBBP6 RBBP6 Q7Z6E9 E3 ubiquitin-protein ligase RBBP6 chr16 GO:0006974 Not Cancer Driver No 229 0.128 1626 212 0.13 0
RBM24 RBM24 Q9BX46 RNA-binding protein 24 chr6 GO:0006974 Not Cancer Driver No 29 0.123 20 3 0.15 0
RCHY1 RCHY1 Q96PM5 RING finger and CHY zinc finger domain-containing protein 1 chr4 GO:0006974 Not Cancer Driver No 33 0.126 23 0 0.0 0
REC8_ENST00000611366 REC8 O95072 Meiotic recombination protein REC8 homolog chr14 GO:0006974 Not Cancer Driver No 60 0.11 244 26 0.107 0
RECQL5 RECQL5 O94762 ATP-dependent DNA helicase Q5 chr17 GO:0006974 Not Cancer Driver No 132 0.133 495 71 0.143 0
REV1 REV1 Q9UBZ9 DNA repair protein REV1 chr2 GO:0006974 Not Cancer Driver No 122 0.098 660 67 0.102 0
REV3L_ENST00000368802 REV3L O60673 DNA polymerase zeta catalytic subunit chr6 GO:0006974 Not Cancer Driver No 379 0.121 1665 211 0.127 0
RFWD3 RFWD3 Q6PCD5 E3 ubiquitin-protein ligase RFWD3 chr16 GO:0006974 Census Yes 68 0.088 318 30 0.094 1
RIF1 RIF1 Q5UIP0 Telomere-associated protein RIF1 chr2 GO:0006974 Not Cancer Driver No 287 0.116 1355 164 0.121 0
RNF111_ENST00000557998 RNF111 Q6ZNA4 E3 ubiquitin-protein ligase Arkadia chr15 GO:0006974 Not Cancer Driver No 111 0.112 855 96 0.112 0
RNF168 RNF168 Q8IYW5 E3 ubiquitin-protein ligase RNF168 chr3 GO:0006974 Not Cancer Driver No 77 0.135 471 66 0.14 0
RNF169 RNF169 Q8NCN4 E3 ubiquitin-protein ligase RNF169 chr11 GO:0006974 Not Cancer Driver No 52 0.073 637 46 0.072 0
RNF8 RNF8 O76064 E3 ubiquitin-protein ligase RNF8 chr6 GO:0006974 Not Cancer Driver No 56 0.115 226 29 0.128 0
RPA1 RPA1 P27694 Replication protein A 70 kDa DNA-binding subunit chr17 GO:0006974 Not Cancer Driver No 51 0.083 98 6 0.061 0
RPA2_ENST00000373912 RPA2 P15927 Replication protein A 32 kDa subunit chr1 GO:0006974 Not Cancer Driver No 28 0.104 114 16 0.14 0
RPL26 RPL26 P61254 60S ribosomal protein L26 chr17 GO:0006974 Not Cancer Driver No 16 0.11 114 13 0.114 0
RPS27L RPS27L Q71UM5 40S ribosomal protein S27-like chr15 GO:0006974 Not Cancer Driver No 4 0.048 22 2 0.091 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0006974 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6KA6_ENST00000262752 RPS6KA6 Q9UK32 Ribosomal protein S6 kinase alpha-6 chrX GO:0006974 Not Cancer Driver No 180 0.242 136 36 0.265 0
RTEL1_ENST00000370018 RTEL1 Q9NZ71 Regulator of telomere elongation helicase 1 chr20 GO:0006974 Not Cancer Driver No 144 0.118 474 64 0.135 14
SAMHD1 SAMHD1 Q9Y3Z3 Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 chr20 GO:0006974 Not Cancer Driver No 104 0.166 91 14 0.154 13
SDE2 SDE2 Q6IQ49 Replication stress response regulator SDE2 chr1 GO:0006974 Not Cancer Driver No 56 0.124 290 35 0.121 0
SESN2 SESN2 P58004 Sestrin-2 chr1 GO:0006974 Not Cancer Driver No 74 0.154 147 26 0.177 0
SETD1A SETD1A O15047 Histone-lysine N-methyltransferase SETD1A chr16 GO:0006974 Not Cancer Driver No 223 0.131 1327 188 0.142 5
SETD7 SETD7 Q8WTS6 Histone-lysine N-methyltransferase SETD7 chr4 GO:0006974 Not Cancer Driver No 42 0.115 105 7 0.067 0
SETX SETX Q7Z333 Probable helicase senataxin chr9 GO:0006974 Not Cancer Driver No 342 0.128 1240 156 0.126 20
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0006974 Census, Compendium Yes 58 0.135 86 16 0.186 0
SHPRH SHPRH Q149N8 E3 ubiquitin-protein ligase SHPRH chr6 GO:0006974 Not Cancer Driver No 227 0.135 359 51 0.142 0
SIRT1 SIRT1 Q96EB6 NAD-dependent protein deacetylase sirtuin-1 chr10 GO:0006974 Not Cancer Driver No 70 0.094 435 31 0.071 0
SIRT4 SIRT4 Q9Y6E7 NAD-dependent protein lipoamidase sirtuin-4, mitochondrial chr12 GO:0006974 Not Cancer Driver No 46 0.146 4 0 0.0 0
SIRT7 SIRT7 Q9NRC8 NAD-dependent protein deacetylase sirtuin-7 chr17 GO:0006974 Not Cancer Driver No 48 0.12 163 15 0.092 0
SLF1 SLF1 Q9BQI6 SMC5-SMC6 complex localization factor protein 1 chr5 GO:0006974 Not Cancer Driver No 104 0.098 167 12 0.072 0
SLF2_ENST00000238961 SLF2 Q8IX21 SMC5-SMC6 complex localization factor protein 2 chr10 GO:0006974 Not Cancer Driver No 112 0.095 725 76 0.105 0
SLFN11_ENST00000308377 SLFN11 Q7Z7L1 Schlafen family member 11 chr17 GO:0006974 Not Cancer Driver No 177 0.196 34 8 0.235 0
SMARCAL1 SMARCAL1 Q9NZC9 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 chr2 GO:0006974 Not Cancer Driver No 128 0.134 335 49 0.146 11
SMC5 SMC5 Q8IY18 Structural maintenance of chromosomes protein 5 chr9 GO:0006974 Not Cancer Driver No 126 0.114 378 43 0.114 0
SMC6_ENST00000351948 SMC6 Q96SB8 Structural maintenance of chromosomes protein 6 chr2 GO:0006974 Not Cancer Driver No 128 0.117 458 57 0.124 0
SP100_ENST00000264052 SP100 P23497 Nuclear autoantigen Sp-100 chr2 GO:0006974 Not Cancer Driver No 136 0.155 680 101 0.149 0
SPATA18 SPATA18 Q8TC71 Mitochondria-eating protein chr4 GO:0006974 Not Cancer Driver No 129 0.24 222 49 0.221 0
SPDYA_ENST00000379579 SPDYA Q5MJ70 Speedy protein A chr2 GO:0006974 Not Cancer Driver No 39 0.125 119 11 0.092 0
SPIDR SPIDR Q14159 DNA repair-scaffolding protein chr8 GO:0006974 Not Cancer Driver No 101 0.11 329 20 0.061 0
SPO11 SPO11 Q9Y5K1 Meiotic recombination protein SPO11 chr20 GO:0006974 Not Cancer Driver No 59 0.149 26 5 0.192 0
SPRTN SPRTN Q9H040 DNA-dependent metalloprotease SPRTN chr1 GO:0006974 Not Cancer Driver No 73 0.149 252 38 0.151 1
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0006974 Census, Compendium Yes 75 0.173 135 14 0.104 9
STXBP4 STXBP4 Q6ZWJ1 Syntaxin-binding protein 4 chr17 GO:0006974 Not Cancer Driver No 78 0.141 211 24 0.114 0
SUSD6 SUSD6 Q92537 Sushi domain-containing protein 6 chr14 GO:0006974 Not Cancer Driver No 27 0.089 134 8 0.06 0
SUV39H1_ENST00000376687 SUV39H1 O43463 Histone-lysine N-methyltransferase SUV39H1 chrX GO:0006974 Not Cancer Driver No 59 0.143 15 1 0.067 0
TAF1_ENST00000373790 TAF1 P21675 Transcription initiation factor TFIID subunit 1 chrX GO:0006974 Not Cancer Driver No 379 0.202 1152 219 0.19 5
TAF9 TAF9 Q16594 Transcription initiation factor TFIID subunit 9 chr5 GO:0006974 Not Cancer Driver No 25 0.095 203 19 0.094 0
TANK TANK Q92844 TRAF family member-associated NF-kappa-B activator chr2 GO:0006974 Not Cancer Driver No 42 0.099 302 26 0.086 0
TAOK1 TAOK1 Q7L7X3 Serine/threonine-protein kinase TAO1 chr17 GO:0006974 Not Cancer Driver No 116 0.116 601 59 0.098 0
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0006974 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAOK3 TAOK3 Q9H2K8 Serine/threonine-protein kinase TAO3 chr12 GO:0006974 Not Cancer Driver No 123 0.137 494 64 0.13 0
TDP1_ENST00000393454 TDP1 Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 chr14 GO:0006974 Not Cancer Driver No 81 0.133 179 25 0.14 1
TERF2 TERF2 Q15554 Telomeric repeat-binding factor 2 chr16 GO:0006974 Not Cancer Driver No 33 0.061 361 20 0.055 0
TERF2IP TERF2IP Q9NYB0 Telomeric repeat-binding factor 2-interacting protein 1 chr16 GO:0006974 Not Cancer Driver No 28 0.07 310 16 0.052 0
TEX264_ENST00000416589 TEX264 Q9Y6I9 Testis-expressed protein 264 chr3 GO:0006974 Not Cancer Driver No 40 0.128 107 11 0.103 0
TFAP4 TFAP4 Q01664 Transcription factor AP-4 chr16 GO:0006974 Compendium Yes 61 0.18 285 52 0.182 0
TFDP3 TFDP3 Q5H9I0 Transcription factor Dp family member 3 chrX GO:0006974 Not Cancer Driver No 84 0.207 186 42 0.226 0
TFIP11_ENST00000407148 TFIP11 Q9UBB9 Tuftelin-interacting protein 11 chr22 GO:0006974 Not Cancer Driver No 87 0.104 331 39 0.118 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0006974 Not Cancer Driver No 44 0.163 39 9 0.231 0
TIMELESS TIMELESS Q9UNS1 Protein timeless homolog chr12 GO:0006974 Not Cancer Driver No 154 0.127 367 51 0.139 0
TLK1 TLK1 Q9UKI8 Serine/threonine-protein kinase tousled-like 1 chr2 GO:0006974 Not Cancer Driver No 103 0.134 388 53 0.137 0
TLK2 TLK2 Q86UE8 Serine/threonine-protein kinase tousled-like 2 chr17 GO:0006974 Not Cancer Driver No 120 0.155 436 58 0.133 5
TNP1 TNP1 P09430 Spermatid nuclear transition protein 1 chr2 GO:0006974 Not Cancer Driver No 21 0.382 55 21 0.382 0
TOP2A TOP2A P11388 DNA topoisomerase 2-alpha chr17 GO:0006974 Compendium Yes 150 0.098 508 59 0.116 0
TOPBP1 TOPBP1 Q92547 DNA topoisomerase 2-binding protein 1 chr3 GO:0006974 Not Cancer Driver No 169 0.111 577 59 0.102 0
TOPORS TOPORS Q9NS56 E3 ubiquitin-protein ligase Topors chr9 GO:0006974 Not Cancer Driver No 149 0.143 795 105 0.132 0
TP53BP1_ENST00000263801 TP53BP1 Q12888 TP53-binding protein 1 chr15 GO:0006974 Not Cancer Driver No 227 0.115 1632 190 0.116 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0006974 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP73 TP73 O15350 Tumor protein p73 chr1 GO:0006974 Not Cancer Driver No 82 0.129 443 55 0.124 0
TRAF6_ENST00000348124 TRAF6 Q9Y4K3 TNF receptor-associated factor 6 chr11 GO:0006974 Not Cancer Driver No 67 0.128 62 7 0.113 0
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0006974 Not Cancer Driver No 63 0.134 240 33 0.138 1
TREX1_ENST00000625293 TREX1 Q9NSU2 Three-prime repair exonuclease 1 chr3 GO:0006974 Not Cancer Driver No 26 0.083 98 10 0.102 18
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0006974 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIP12_ENST00000283943 TRIP12 Q14669 E3 ubiquitin-protein ligase TRIP12 chr2 GO:0006974 Not Cancer Driver No 224 0.112 845 117 0.138 4
TTC5 TTC5 Q8N0Z6 Tetratricopeptide repeat protein 5 chr14 GO:0006974 Not Cancer Driver No 65 0.148 151 19 0.126 0
UBA1 UBA1 P22314 Ubiquitin-like modifier-activating enzyme 1 chrX GO:0006974 Not Cancer Driver No 117 0.111 165 22 0.133 6
UBA6 UBA6 A0AVT1 Ubiquitin-like modifier-activating enzyme 6 chr4 GO:0006974 Not Cancer Driver No 133 0.126 90 10 0.111 0
UBA7 UBA7 P41226 Ubiquitin-like modifier-activating enzyme 7 chr3 GO:0006974 Not Cancer Driver No 92 0.091 166 15 0.09 0
UBE2B UBE2B P63146 Ubiquitin-conjugating enzyme E2 B chr5 GO:0006974 Not Cancer Driver No 13 0.086 68 6 0.088 0
UBE2E2_ENST00000425792 UBE2E2 Q96LR5 Ubiquitin-conjugating enzyme E2 E2 chr3 GO:0006974 Not Cancer Driver No 28 0.139 90 15 0.167 0
UBE2T UBE2T Q9NPD8 Ubiquitin-conjugating enzyme E2 T chr1 GO:0006974 Not Cancer Driver No 12 0.061 97 9 0.093 1
UBE2V2 UBE2V2 Q15819 Ubiquitin-conjugating enzyme E2 variant 2 chr8 GO:0006974 Not Cancer Driver No 22 0.152 76 12 0.158 0
UBQLN4 UBQLN4 Q9NRR5 Ubiquilin-4 chr1 GO:0006974 Not Cancer Driver No 70 0.116 561 67 0.119 1
UBR5 UBR5 O95071 E3 ubiquitin-protein ligase UBR5 chr8 GO:0006974 Census, Compendium Yes 340 0.121 1296 162 0.125 0
UFL1 UFL1 O94874 E3 UFM1-protein ligase 1 chr6 GO:0006974 Not Cancer Driver No 109 0.137 141 24 0.17 0
USP10_ENST00000219473 USP10 Q14694 Ubiquitin carboxyl-terminal hydrolase 10 chr16 GO:0006974 Not Cancer Driver No 92 0.115 425 49 0.115 0
USP16 USP16 Q9Y5T5 Ubiquitin carboxyl-terminal hydrolase 16 chr21 GO:0006974 Not Cancer Driver No 98 0.119 394 42 0.107 0
USP28 USP28 Q96RU2 Ubiquitin carboxyl-terminal hydrolase 28 chr11 GO:0006974 Not Cancer Driver No 151 0.14 311 25 0.08 0
USP45 USP45 Q70EL2 Ubiquitin carboxyl-terminal hydrolase 45 chr6 GO:0006974 Not Cancer Driver No 96 0.118 275 28 0.102 0
USP47 USP47 Q96K76 Ubiquitin carboxyl-terminal hydrolase 47 chr11 GO:0006974 Not Cancer Driver No 137 0.1 425 39 0.092 0
USP7 USP7 Q93009 Ubiquitin carboxyl-terminal hydrolase 7 chr16 GO:0006974 Not Cancer Driver No 170 0.154 215 45 0.209 0
UVRAG UVRAG Q9P2Y5 UV radiation resistance-associated gene protein chr11 GO:0006974 Not Cancer Driver No 89 0.127 243 28 0.115 0
UVSSA UVSSA Q2YD98 UV-stimulated scaffold protein A chr4 GO:0006974 Not Cancer Driver No 101 0.142 519 70 0.135 1
VAV3 VAV3 Q9UKW4 Guanine nucleotide exchange factor VAV3 chr1 GO:0006974 Not Cancer Driver No 153 0.181 102 18 0.176 0
VCP VCP P55072 Transitional endoplasmic reticulum ATPase chr9 GO:0006974 Not Cancer Driver No 88 0.109 186 16 0.086 16
VCPIP1 VCPIP1 Q96JH7 Deubiquitinating protein VCPIP1 chr8 GO:0006974 Not Cancer Driver No 133 0.109 543 61 0.112 0
WAC WAC Q9BTA9 WW domain-containing adapter protein with coiled-coil chr10 GO:0006974 Not Cancer Driver No 106 0.164 571 95 0.166 0
WDR4 WDR4 P57081 tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 chr21 GO:0006974 Not Cancer Driver No 37 0.09 49 4 0.082 2
WDR48 WDR48 Q8TAF3 WD repeat-containing protein 48 chr3 GO:0006974 Not Cancer Driver No 61 0.09 125 19 0.152 0
WDR76 WDR76 Q9H967 WD repeat-containing protein 76 chr15 GO:0006974 Not Cancer Driver No 60 0.096 288 33 0.115 0
WRN WRN Q14191 Werner syndrome ATP-dependent helicase chr8 GO:0006974 Census, Compendium Yes 164 0.115 373 41 0.11 2
XAB2 XAB2 Q9HCS7 Pre-mRNA-splicing factor SYF1 chr19 GO:0006974 Not Cancer Driver No 128 0.15 127 17 0.134 0
XIAP_ENST00000434753 XIAP P98170 E3 ubiquitin-protein ligase XIAP chrX GO:0006974 Not Cancer Driver No 89 0.179 55 6 0.109 0
XPA XPA P23025 DNA repair protein complementing XP-A cells chr9 GO:0006974 Census Yes 27 0.099 121 13 0.107 5
XPC XPC Q01831 DNA repair protein complementing XP-C cells chr3 GO:0006974 Census, Compendium Yes 88 0.094 479 48 0.1 2
XRCC1 XRCC1 P18887 DNA repair protein XRCC1 chr19 GO:0006974 Not Cancer Driver No 85 0.134 426 53 0.124 1
XRCC3_ENST00000352127 XRCC3 O43542 DNA repair protein XRCC3 chr14 GO:0006974 Not Cancer Driver No 24 0.069 35 2 0.057 1
XRCC5_ENST00000392132 XRCC5 P13010 X-ray repair cross-complementing protein 5 chr2 GO:0006974 Not Cancer Driver No 87 0.119 118 11 0.093 0
XRCC6 XRCC6 P12956 X-ray repair cross-complementing protein 6 chr22 GO:0006974 Not Cancer Driver No 66 0.108 140 12 0.086 0
YAP1_ENST00000282441 YAP1 P46937 Transcriptional coactivator YAP1 chr11 GO:0006974 Not Cancer Driver No 51 0.101 489 49 0.1 0
YY1 YY1 P25490 Transcriptional repressor protein YY1 chr14 GO:0006974 Not Cancer Driver No 37 0.089 336 26 0.077 2
ZBTB1 ZBTB1 Q9Y2K1 Zinc finger and BTB domain-containing protein 1 chr14 GO:0006974 Not Cancer Driver No 70 0.098 271 27 0.1 0
ZBTB38_ENST00000441582 ZBTB38 Q8NAP3 Zinc finger and BTB domain-containing protein 38 chr3 GO:0006974 Not Cancer Driver No 137 0.115 648 73 0.113 0
ZBTB40 ZBTB40 Q9NUA8 Zinc finger and BTB domain-containing protein 40 chr1 GO:0006974 Not Cancer Driver No 143 0.115 403 48 0.119 0
ZBTB4_ENST00000380599 ZBTB4 Q9P1Z0 Zinc finger and BTB domain-containing protein 4 chr17 GO:0006974 Not Cancer Driver No 140 0.138 788 109 0.138 0
ZBTB7A_ENST00000601588 ZBTB7A O95365 Zinc finger and BTB domain-containing protein 7A chr19 GO:0006974 Not Cancer Driver No 60 0.103 285 30 0.105 0
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0006974 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZDHHC16_ENST00000370854 ZDHHC16 Q969W1 Palmitoyltransferase ZDHHC16 chr10 GO:0006974 Not Cancer Driver No 41 0.109 9 1 0.111 0
ZMAT3 ZMAT3 Q9HA38 Zinc finger matrin-type protein 3 chr3 GO:0006974 Not Cancer Driver No 48 0.166 217 41 0.189 0
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0006974 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZRANB3 ZRANB3 Q5FWF4 DNA annealing helicase and endonuclease ZRANB3 chr2 GO:0006974 Not Cancer Driver No 126 0.117 261 31 0.119 0