Total number of protein in "GO:0006970" GO term: 63
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKR1B1 | AKR1B1 | P15121 | Aldo-keto reductase family 1 member B1 | chr7 | GO:0006970 | Not Cancer Driver | No | 52 | 0.165 | 19 | 1 | 0.053 | 0 |
| AQP1 | AQP1 | P29972 | Aquaporin-1 | chr7 | GO:0006970 | Not Cancer Driver | No | 39 | 0.145 | 4 | 1 | 0.25 | 0 |
| AQP4 | AQP4 | P55087 | Aquaporin-4 | chr18 | GO:0006970 | Not Cancer Driver | No | 50 | 0.155 | 30 | 9 | 0.3 | 0 |
| AQP5 | AQP5 | P55064 | Aquaporin-5 | chr12 | GO:0006970 | Not Cancer Driver | No | 31 | 0.117 | 21 | 2 | 0.095 | 5 |
| AQP9 | AQP9 | O43315 | Aquaporin-9 | chr15 | GO:0006970 | Not Cancer Driver | No | 75 | 0.254 | 12 | 0 | 0.0 | 0 |
| ARHGEF2 | ARHGEF2 | Q92974 | Rho guanine nucleotide exchange factor 2 | chr1 | GO:0006970 | Not Cancer Driver | No | 146 | 0.148 | 450 | 70 | 0.156 | 0 |
| ATF2 | ATF2 | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | chr2 | GO:0006970 | Not Cancer Driver | No | 65 | 0.129 | 451 | 58 | 0.129 | 0 |
| AVP | AVP | P01185 | Vasopressin-neurophysin 2-copeptin | chr20 | GO:0006970 | Not Cancer Driver | No | 14 | 0.085 | 26 | 0 | 0.0 | 39 |
| AVPR1B | AVPR1B | P47901 | Vasopressin V1b receptor | chr1 | GO:0006970 | Not Cancer Driver | No | 83 | 0.196 | 51 | 5 | 0.098 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0006970 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BDKRB2 | BDKRB2 | P30411 | B2 bradykinin receptor | chr14 | GO:0006970 | Not Cancer Driver | No | 81 | 0.207 | 0 | 0 | 0.0 | 0 |
| CAB39 | CAB39 | Q9Y376 | Calcium-binding protein 39 | chr2 | GO:0006970 | Not Cancer Driver | No | 31 | 0.091 | 43 | 5 | 0.116 | 0 |
| CAPN3 | CAPN3 | P20807 | Calpain-3 | chr15 | GO:0006970 | Not Cancer Driver | No | 111 | 0.135 | 168 | 11 | 0.065 | 52 |
| CASP3 | CASP3 | P42574 | Caspase-3 | chr4 | GO:0006970 | Census | Yes | 32 | 0.116 | 62 | 5 | 0.081 | 0 |
| CLDN1 | CLDN1 | O95832 | Claudin-1 | chr3 | GO:0006970 | Not Cancer Driver | No | 31 | 0.147 | 16 | 3 | 0.188 | 0 |
| EPO | EPO | P01588 | Erythropoietin | chr7 | GO:0006970 | Not Cancer Driver | No | 27 | 0.14 | 9 | 1 | 0.111 | 1 |
| ERRFI1 | ERRFI1 | Q9UJM3 | ERBB receptor feedback inhibitor 1 | chr1 | GO:0006970 | Not Cancer Driver | No | 55 | 0.119 | 297 | 37 | 0.125 | 0 |
| FMO1 | FMO1 | Q01740 | Dimethylaniline monooxygenase [N-oxide-forming] 1 | chr1 | GO:0006970 | Not Cancer Driver | No | 133 | 0.25 | 3 | 0 | 0.0 | 0 |
| HSP90AB1 | HSP90AB1 | P08238 | Heat shock protein HSP 90-beta | chr6 | GO:0006970 | Census, Compendium | Yes | 100 | 0.138 | 254 | 43 | 0.169 | 0 |
| ICOSLG_ENST00000407780 | ICOSLG | O75144 | ICOS ligand | chr21 | GO:0006970 | Not Cancer Driver | No | 25 | 0.083 | 30 | 2 | 0.067 | 0 |
| ITGA2 | ITGA2 | P17301 | Integrin alpha-2 | chr5 | GO:0006970 | Not Cancer Driver | No | 166 | 0.141 | 26 | 0 | 0.0 | 0 |
| KCNMA1 | KCNMA1 | Q12791 | Calcium-activated potassium channel subunit alpha-1 | chr10 | GO:0006970 | Not Cancer Driver | No | 222 | 0.18 | 225 | 39 | 0.173 | 5 |
| KMO | KMO | O15229 | Kynurenine 3-monooxygenase | chr1 | GO:0006970 | Not Cancer Driver | No | 77 | 0.158 | 0 | 0 | 0.0 | 0 |
| LRRC8A_ENST00000372599 | LRRC8A | Q8IWT6 | Volume-regulated anion channel subunit LRRC8A | chr9 | GO:0006970 | Not Cancer Driver | No | 105 | 0.13 | 32 | 3 | 0.094 | 0 |
| MAP2K7_ENST00000397979 | MAP2K7 | O14733 | Dual specificity mitogen-activated protein kinase kinase 7 | chr19 | GO:0006970 | Compendium | Yes | 89 | 0.212 | 144 | 20 | 0.139 | 0 |
| MAP7_ENST00000354570 | MAP7 | Q14244 | Ensconsin | chr6 | GO:0006970 | Not Cancer Driver | No | 122 | 0.163 | 745 | 122 | 0.164 | 0 |
| MAPK13 | MAPK13 | O15264 | Mitogen-activated protein kinase 13 | chr6 | GO:0006970 | Not Cancer Driver | No | 51 | 0.14 | 50 | 15 | 0.3 | 0 |
| MARVELD3_ENST00000268485 | MARVELD3 | Q96A59 | MARVEL domain-containing protein 3 | chr16 | GO:0006970 | Not Cancer Driver | No | 40 | 0.1 | 179 | 10 | 0.056 | 0 |
| MYLK | MYLK | Q15746 | Myosin light chain kinase, smooth muscle | chr3 | GO:0006970 | Not Cancer Driver | No | 343 | 0.179 | 957 | 184 | 0.192 | 3 |
| NFAT5_ENST00000354436 | NFAT5 | O94916 | Nuclear factor of activated T-cells 5 | chr16 | GO:0006970 | Not Cancer Driver | No | 142 | 0.093 | 1307 | 119 | 0.091 | 0 |
| NOLC1_ENST00000605788 | NOLC1 | Q14978 | Nucleolar and coiled-body phosphoprotein 1 | chr10 | GO:0006970 | Not Cancer Driver | No | 74 | 0.106 | 662 | 69 | 0.104 | 0 |
| OXSR1 | OXSR1 | O95747 | Serine/threonine-protein kinase OSR1 | chr3 | GO:0006970 | Not Cancer Driver | No | 69 | 0.131 | 208 | 29 | 0.139 | 0 |
| OXT | OXT | P01178 | Oxytocin-neurophysin 1 | chr20 | GO:0006970 | Not Cancer Driver | No | 10 | 0.08 | 0 | 0 | 0.0 | 0 |
| PAPPA2 | PAPPA2 | Q9BXP8 | Pappalysin-2 | chr1 | GO:0006970 | Not Cancer Driver | No | 739 | 0.413 | 370 | 141 | 0.381 | 1 |
| PDPK1 | PDPK1 | O15530 | 3-phosphoinositide-dependent protein kinase 1 | chr16 | GO:0006970 | Not Cancer Driver | No | 33 | 0.059 | 121 | 12 | 0.099 | 0 |
| PKN1_ENST00000242783 | PKN1 | Q16512 | Serine/threonine-protein kinase N1 | chr19 | GO:0006970 | Not Cancer Driver | No | 120 | 0.127 | 459 | 54 | 0.118 | 0 |
| PLK3 | PLK3 | Q9H4B4 | Serine/threonine-protein kinase PLK3 | chr1 | GO:0006970 | Not Cancer Driver | No | 75 | 0.116 | 202 | 15 | 0.074 | 0 |
| PTGS2 | PTGS2 | P35354 | Prostaglandin G/H synthase 2 | chr1 | GO:0006970 | Not Cancer Driver | No | 105 | 0.174 | 30 | 5 | 0.167 | 0 |
| PTK2B_ENST00000346049 | PTK2B | Q14289 | Protein-tyrosine kinase 2-beta | chr8 | GO:0006970 | Not Cancer Driver | No | 161 | 0.16 | 261 | 37 | 0.142 | 0 |
| RCSD1 | RCSD1 | Q6JBY9 | CapZ-interacting protein | chr1 | GO:0006970 | Not Cancer Driver | No | 70 | 0.168 | 416 | 70 | 0.168 | 0 |
| SCN2A_ENST00000637266 | SCN2A | Q99250 | Sodium channel protein type 2 subunit alpha | chr2 | GO:0006970 | Not Cancer Driver | No | 502 | 0.25 | 435 | 133 | 0.306 | 65 |
| SLC12A2 | SLC12A2 | P55011 | Solute carrier family 12 member 2 | chr5 | GO:0006970 | Not Cancer Driver | No | 141 | 0.116 | 297 | 18 | 0.061 | 8 |
| SLC12A5 | SLC12A5 | Q9H2X9 | Solute carrier family 12 member 5 | chr20 | GO:0006970 | Not Cancer Driver | No | 263 | 0.231 | 290 | 59 | 0.203 | 5 |
| SLC12A6_ENST00000558667 | SLC12A6 | Q9UHW9 | Solute carrier family 12 member 6 | chr15 | GO:0006970 | Not Cancer Driver | No | 168 | 0.146 | 280 | 46 | 0.164 | 0 |
| SLC2A1 | SLC2A1 | P11166 | Solute carrier family 2, facilitated glucose transporter member 1 | chr1 | GO:0006970 | Not Cancer Driver | No | 51 | 0.104 | 13 | 2 | 0.154 | 48 |
| SLC4A11_ENST00000539553 | SLC4A11 | Q8NBS3 | Solute carrier family 4 member 11 | chr20 | GO:0006970 | Not Cancer Driver | No | 159 | 0.182 | 69 | 10 | 0.145 | 42 |
| SLC9A4 | SLC9A4 | Q6AI14 | Sodium/hydrogen exchanger 4 | chr2 | GO:0006970 | Not Cancer Driver | No | 197 | 0.247 | 197 | 77 | 0.391 | 0 |
| SORD | SORD | Q00796 | Sorbitol dehydrogenase | chr15 | GO:0006970 | Not Cancer Driver | No | 29 | 0.081 | 41 | 7 | 0.171 | 3 |
| SST | SST | P61278 | Somatostatin | chr3 | GO:0006970 | Not Cancer Driver | No | 25 | 0.216 | 40 | 15 | 0.375 | 0 |
| STK39 | STK39 | Q9UEW8 | STE20/SPS1-related proline-alanine-rich protein kinase | chr2 | GO:0006970 | Not Cancer Driver | No | 64 | 0.117 | 182 | 19 | 0.104 | 0 |
| TACR3 | TACR3 | P29371 | Neuromedin-K receptor | chr4 | GO:0006970 | Not Cancer Driver | No | 137 | 0.295 | 31 | 17 | 0.548 | 5 |
| TH | TH | P07101 | Tyrosine 3-monooxygenase | chr11 | GO:0006970 | Not Cancer Driver | No | 61 | 0.116 | 149 | 21 | 0.141 | 38 |
| TLR3 | TLR3 | O15455 | Toll-like receptor 3 | chr4 | GO:0006970 | Not Cancer Driver | No | 123 | 0.136 | 0 | 0 | 0.0 | 1 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0006970 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TP53_ENST00000445888 | TP53 | P04637 | Cellular tumor antigen p53 | chr17 | GO:0006970 | Census, Compendium | Yes | 2891 | 7.356 | 282 | 1466 | 5.199 | 83 |
| TRPV4 | TRPV4 | Q9HBA0 | Transient receptor potential cation channel subfamily V member 4 | chr12 | GO:0006970 | Not Cancer Driver | No | 142 | 0.163 | 231 | 34 | 0.147 | 44 |
| TSC22D3_ENST00000372397 | TSC22D3 | Q99576 | TSC22 domain family protein 3 | chrX | GO:0006970 | Not Cancer Driver | No | 18 | 0.134 | 51 | 9 | 0.176 | 0 |
| TSC22D4 | TSC22D4 | Q9Y3Q8 | TSC22 domain family protein 4 | chr7 | GO:0006970 | Not Cancer Driver | No | 33 | 0.084 | 363 | 29 | 0.08 | 0 |
| TSPO_ENST00000329563 | TSPO | P30536 | Translocator protein | chr22 | GO:0006970 | Not Cancer Driver | No | 5 | 0.03 | 1 | 0 | 0.0 | 0 |
| WNK3_ENST00000375159 | WNK3 | Q9BYP7 | Serine/threonine-protein kinase WNK3 | chrX | GO:0006970 | Not Cancer Driver | No | 281 | 0.156 | 1281 | 200 | 0.156 | 0 |
| XRCC5_ENST00000392132 | XRCC5 | P13010 | X-ray repair cross-complementing protein 5 | chr2 | GO:0006970 | Not Cancer Driver | No | 87 | 0.119 | 118 | 11 | 0.093 | 0 |
| YBX3 | YBX3 | P16989 | Y-box-binding protein 3 | chr12 | GO:0006970 | Not Cancer Driver | No | 49 | 0.132 | 359 | 47 | 0.131 | 0 |
| ZFP36L1 | ZFP36L1 | Q07352 | mRNA decay activator protein ZFP36L1 | chr14 | GO:0006970 | Compendium | Yes | 57 | 0.169 | 212 | 30 | 0.142 | 0 |