Total number of protein in "GO:0006919" GO term: 80
| Identifier | UniProt Gene | UniProt Accession | UniProt Name | Chromosome | GO term | Database | Cancer Driver | Number of missense mutations | Missense mutation per residues | Number of disordered residues | Number of mutations in disordered regions | Disordered missense mutations per residues | Number of OMIM mutation |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ACER2 | ACER2 | Q5QJU3 | Alkaline ceramidase 2 | chr9 | GO:0006919 | Not Cancer Driver | No | 27 | 0.098 | 0 | 0 | 0.0 | 0 |
| AIFM1 | AIFM1 | O95831 | Apoptosis-inducing factor 1, mitochondrial | chrX | GO:0006919 | Not Cancer Driver | No | 88 | 0.144 | 166 | 22 | 0.133 | 11 |
| ANP32B | ANP32B | Q92688 | Acidic leucine-rich nuclear phosphoprotein 32 family member B | chr9 | GO:0006919 | Not Cancer Driver | No | 22 | 0.088 | 117 | 12 | 0.103 | 0 |
| APAF1 | APAF1 | O14727 | Apoptotic protease-activating factor 1 | chr12 | GO:0006919 | Not Cancer Driver | No | 127 | 0.102 | 17 | 1 | 0.059 | 0 |
| ATP2A3_ENST00000397041 | ATP2A3 | Q93084 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 | chr17 | GO:0006919 | Not Cancer Driver | No | 130 | 0.13 | 147 | 16 | 0.109 | 0 |
| BAD_ENST00000309032 | BAD | Q92934 | Bcl2-associated agonist of cell death | chr11 | GO:0006919 | Not Cancer Driver | No | 14 | 0.083 | 163 | 14 | 0.086 | 0 |
| BAK1 | BAK1 | Q16611 | Bcl-2 homologous antagonist/killer | chr6 | GO:0006919 | Not Cancer Driver | No | 38 | 0.18 | 58 | 9 | 0.155 | 0 |
| BAX_ENST00000345358 | BAX | Q07812 | Apoptosis regulator BAX | chr19 | GO:0006919 | Census | Yes | 30 | 0.156 | 39 | 2 | 0.051 | 0 |
| BBC3 | BBC3 | Q96PG8 | Bcl-2-binding component 3, isoforms 3/4 | chr19 | GO:0006919 | Not Cancer Driver | No | 20 | 0.077 | 253 | 20 | 0.079 | 0 |
| BCL2L10_ENST00000260442 | BCL2L10 | Q9HD36 | Bcl-2-like protein 10 | chr15 | GO:0006919 | Not Cancer Driver | No | 10 | 0.049 | 34 | 1 | 0.029 | 0 |
| BCL2L13_ENST00000317582 | BCL2L13 | Q9BXK5 | Bcl-2-like protein 13 | chr22 | GO:0006919 | Not Cancer Driver | No | 49 | 0.101 | 291 | 30 | 0.103 | 0 |
| BEX3_ENST00000372635 | BEX3 | Q00994 | Protein BEX3 | chrX | GO:0006919 | Not Cancer Driver | No | 19 | 0.171 | 98 | 17 | 0.173 | 0 |
| BID_ENST00000551952 | BID | P55957 | BH3-interacting domain death agonist | chr22 | GO:0006919 | Not Cancer Driver | No | 23 | 0.118 | 74 | 9 | 0.122 | 0 |
| BOK | BOK | Q9UMX3 | Bcl-2-related ovarian killer protein | chr2 | GO:0006919 | Not Cancer Driver | No | 7 | 0.033 | 0 | 0 | 0.0 | 0 |
| CARD8_ENST00000519940 | CARD8 | Q9Y2G2 | Caspase recruitment domain-containing protein 8 | chr19 | GO:0006919 | Not Cancer Driver | No | 53 | 0.099 | 126 | 7 | 0.056 | 1 |
| CASP1 | CASP1 | P29466 | Caspase-1 | chr11 | GO:0006919 | Not Cancer Driver | No | 79 | 0.196 | 87 | 18 | 0.207 | 0 |
| CASP10_ENST00000272879 | CASP10 | Q92851 | Caspase-10 | chr2 | GO:0006919 | Not Cancer Driver | No | 57 | 0.109 | 126 | 17 | 0.135 | 3 |
| CASP12 | CASP12 | Q6UXS9 | Inactive caspase-12 | chr11 | GO:0006919 | Not Cancer Driver | No | 12 | 0.035 | 31 | 1 | 0.032 | 0 |
| CASP2 | CASP2 | P42575 | Caspase-2 | chr7 | GO:0006919 | Not Cancer Driver | No | 63 | 0.139 | 42 | 12 | 0.286 | 0 |
| CASP4 | CASP4 | P49662 | Caspase-4 | chr11 | GO:0006919 | Not Cancer Driver | No | 56 | 0.149 | 102 | 14 | 0.137 | 0 |
| CASP5_ENST00000260315 | CASP5 | P51878 | Caspase-5 | chr11 | GO:0006919 | Not Cancer Driver | No | 103 | 0.237 | 61 | 17 | 0.279 | 0 |
| CASP8AP2 | CASP8AP2 | Q9UKL3 | CASP8-associated protein 2 | chr6 | GO:0006919 | Not Cancer Driver | No | 219 | 0.11 | 1501 | 178 | 0.119 | 0 |
| CASP8_ENST00000432109 | CASP8 | Q14790 | Caspase-8 | chr2 | GO:0006919 | Census, Compendium | Yes | 142 | 0.296 | 106 | 12 | 0.113 | 1 |
| CASP9 | CASP9 | P55211 | Caspase-9 | chr1 | GO:0006919 | Census | Yes | 49 | 0.118 | 71 | 7 | 0.099 | 0 |
| CFLAR | CFLAR | O15519 | CASP8 and FADD-like apoptosis regulator | chr2 | GO:0006919 | Not Cancer Driver | No | 40 | 0.083 | 44 | 2 | 0.045 | 0 |
| COL4A3 | COL4A3 | Q01955 | Collagen alpha-3(IV) chain | chr2 | GO:0006919 | Not Cancer Driver | No | 310 | 0.186 | 1433 | 277 | 0.193 | 13 |
| CRADD_ENST00000332896 | CRADD | P78560 | Death domain-containing protein CRADD | chr12 | GO:0006919 | Not Cancer Driver | No | 35 | 0.176 | 45 | 5 | 0.111 | 1 |
| CTSH | CTSH | P09668 | Pro-cathepsin H | chr15 | GO:0006919 | Not Cancer Driver | No | 45 | 0.134 | 4 | 0 | 0.0 | 0 |
| CYCS_ENST00000409409 | CYCS | P99999 | Cytochrome c | chr7 | GO:0006919 | Not Cancer Driver | No | 12 | 0.114 | 19 | 3 | 0.158 | 1 |
| DAP_ENST00000230895 | DAP | P51397 | Death-associated protein 1 | chr5 | GO:0006919 | Not Cancer Driver | No | 10 | 0.098 | 102 | 10 | 0.098 | 0 |
| DIABLO | DIABLO | Q9NR28 | Diablo IAP-binding mitochondrial protein | chr12 | GO:0006919 | Not Cancer Driver | No | 62 | 0.259 | 54 | 8 | 0.148 | 1 |
| DLC1 | DLC1 | Q96QB1 | Rho GTPase-activating protein 7 | chr8 | GO:0006919 | Not Cancer Driver | No | 331 | 0.217 | 922 | 237 | 0.257 | 0 |
| EGLN3 | EGLN3 | Q9H6Z9 | Prolyl hydroxylase EGLN3 | chr14 | GO:0006919 | Not Cancer Driver | No | 33 | 0.138 | 13 | 0 | 0.0 | 0 |
| EIF2AK3 | EIF2AK3 | Q9NZJ5 | Eukaryotic translation initiation factor 2-alpha kinase 3 | chr2 | GO:0006919 | Not Cancer Driver | No | 149 | 0.134 | 410 | 51 | 0.124 | 1 |
| F2R | F2R | P25116 | Proteinase-activated receptor 1 | chr5 | GO:0006919 | Not Cancer Driver | No | 73 | 0.172 | 19 | 2 | 0.105 | 0 |
| F3 | F3 | P13726 | Tissue factor | chr1 | GO:0006919 | Not Cancer Driver | No | 28 | 0.095 | 61 | 7 | 0.115 | 0 |
| FAM162A | FAM162A | Q96A26 | Protein FAM162A | chr3 | GO:0006919 | Not Cancer Driver | No | 18 | 0.117 | 53 | 8 | 0.151 | 0 |
| FASLG | FASLG | P48023 | Tumor necrosis factor ligand superfamily member 6 | chr1 | GO:0006919 | Not Cancer Driver | No | 65 | 0.231 | 94 | 18 | 0.191 | 1 |
| HIP1 | HIP1 | O00291 | Huntingtin-interacting protein 1 | chr7 | GO:0006919 | Census, Compendium | Yes | 137 | 0.132 | 510 | 70 | 0.137 | 0 |
| HIP1R | HIP1R | O75146 | Huntingtin-interacting protein 1-related protein | chr12 | GO:0006919 | Not Cancer Driver | No | 94 | 0.088 | 524 | 34 | 0.065 | 0 |
| HSPD1 | HSPD1 | P10809 | 60 kDa heat shock protein, mitochondrial | chr2 | GO:0006919 | Not Cancer Driver | No | 61 | 0.106 | 82 | 6 | 0.073 | 2 |
| HSPE1 | HSPE1 | P61604 | 10 kDa heat shock protein, mitochondrial | chr2 | GO:0006919 | Not Cancer Driver | No | 8 | 0.078 | 3 | 0 | 0.0 | 0 |
| IFT57 | IFT57 | Q9NWB7 | Intraflagellar transport protein 57 homolog | chr3 | GO:0006919 | Not Cancer Driver | No | 46 | 0.107 | 219 | 18 | 0.082 | 0 |
| JAK2 | JAK2 | O60674 | Tyrosine-protein kinase JAK2 | chr9 | GO:0006919 | Census, Compendium | Yes | 136 | 0.12 | 59 | 5 | 0.085 | 5 |
| KHDC1 | KHDC1 | Q4VXA5 | KH homology domain-containing protein 1 | chr6 | GO:0006919 | Not Cancer Driver | No | 38 | 0.16 | 23 | 2 | 0.087 | 0 |
| KHDC1L | KHDC1L | Q5JSQ8 | Putative KHDC1-like protein | chr6 | GO:0006919 | Not Cancer Driver | No | 25 | 0.195 | 9 | 2 | 0.222 | 0 |
| LAPTM5 | LAPTM5 | Q13571 | Lysosomal-associated transmembrane protein 5 | chr1 | GO:0006919 | Not Cancer Driver | No | 46 | 0.176 | 16 | 6 | 0.375 | 0 |
| LCK | LCK | P06239 | Tyrosine-protein kinase Lck | chr1 | GO:0006919 | Census | Yes | 86 | 0.169 | 94 | 13 | 0.138 | 1 |
| MAPT_ENST00000262410 | MAPT | P10636 | Microtubule-associated protein tau | chr17 | GO:0006919 | Not Cancer Driver | No | 128 | 0.169 | 750 | 126 | 0.168 | 18 |
| MTCH1 | MTCH1 | Q9NZJ7 | Mitochondrial carrier homolog 1 | chr6 | GO:0006919 | Not Cancer Driver | No | 31 | 0.08 | 102 | 2 | 0.02 | 0 |
| MUL1 | MUL1 | Q969V5 | Mitochondrial ubiquitin ligase activator of NFKB 1 | chr1 | GO:0006919 | Not Cancer Driver | No | 48 | 0.136 | 16 | 2 | 0.125 | 0 |
| NGFR | NGFR | P08138 | Tumor necrosis factor receptor superfamily member 16 | chr17 | GO:0006919 | Not Cancer Driver | No | 57 | 0.133 | 172 | 25 | 0.145 | 0 |
| NKX3-1 | NKX3-1 | Q99801 | Homeobox protein Nkx-3.1 | chr8 | GO:0006919 | Not Cancer Driver | No | 35 | 0.15 | 171 | 16 | 0.094 | 0 |
| NLRC4_ENST00000360906 | NLRC4 | Q9NPP4 | NLR family CARD domain-containing protein 4 | chr2 | GO:0006919 | Not Cancer Driver | No | 205 | 0.2 | 15 | 2 | 0.133 | 3 |
| NLRP12_ENST00000324134 | NLRP12 | P59046 | NACHT, LRR and PYD domains-containing protein 12 | chr19 | GO:0006919 | Not Cancer Driver | No | 310 | 0.292 | 116 | 43 | 0.371 | 0 |
| NLRP1_ENST00000572272 | NLRP1 | Q9C000 | NACHT, LRR and PYD domains-containing protein 1 | chr17 | GO:0006919 | Not Cancer Driver | No | 222 | 0.151 | 340 | 65 | 0.191 | 6 |
| NOD1 | NOD1 | Q9Y239 | Nucleotide-binding oligomerization domain-containing protein 1 | chr7 | GO:0006919 | Not Cancer Driver | No | 130 | 0.136 | 38 | 7 | 0.184 | 0 |
| P2RX1 | P2RX1 | P51575 | P2X purinoceptor 1 | chr17 | GO:0006919 | Not Cancer Driver | No | 59 | 0.148 | 14 | 1 | 0.071 | 0 |
| PDCD2 | PDCD2 | Q16342 | Programmed cell death protein 2 | chr6 | GO:0006919 | Not Cancer Driver | No | 32 | 0.093 | 42 | 6 | 0.143 | 0 |
| PDCD6 | PDCD6 | O75340 | Programmed cell death protein 6 | chr5 | GO:0006919 | Not Cancer Driver | No | 21 | 0.11 | 24 | 1 | 0.042 | 0 |
| PIDD1 | PIDD1 | Q9HB75 | p53-induced death domain-containing protein 1 | chr11 | GO:0006919 | Not Cancer Driver | No | 93 | 0.102 | 137 | 14 | 0.102 | 0 |
| PMAIP1 | PMAIP1 | Q13794 | Phorbol-12-myristate-13-acetate-induced protein 1 | chr18 | GO:0006919 | Not Cancer Driver | No | 2 | 0.037 | 23 | 1 | 0.043 | 0 |
| PML | PML | P29590 | Protein PML | chr15 | GO:0006919 | Census, Compendium | Yes | 112 | 0.127 | 312 | 34 | 0.109 | 0 |
| PPARG | PPARG | P37231 | Peroxisome proliferator-activated receptor gamma | chr3 | GO:0006919 | Census | Yes | 72 | 0.143 | 44 | 4 | 0.091 | 3 |
| PYCARD | PYCARD | Q9ULZ3 | Apoptosis-associated speck-like protein containing a CARD | chr16 | GO:0006919 | Not Cancer Driver | No | 16 | 0.082 | 39 | 4 | 0.103 | 0 |
| RACK1 | RACK1 | P63244 | Receptor of activated protein C kinase 1 | chr5 | GO:0006919 | Not Cancer Driver | No | 34 | 0.107 | 13 | 0 | 0.0 | 0 |
| ROBO1 | ROBO1 | Q9Y6N7 | Roundabout homolog 1 | chr3 | GO:0006919 | Not Cancer Driver | No | 353 | 0.214 | 1122 | 234 | 0.209 | 0 |
| RPS27L | RPS27L | Q71UM5 | 40S ribosomal protein S27-like | chr15 | GO:0006919 | Not Cancer Driver | No | 4 | 0.048 | 22 | 2 | 0.091 | 0 |
| S100A8 | S100A8 | P05109 | Protein S100-A8 | chr1 | GO:0006919 | Not Cancer Driver | No | 22 | 0.237 | 8 | 4 | 0.5 | 0 |
| S100A9 | S100A9 | P06702 | Protein S100-A9 | chr1 | GO:0006919 | Not Cancer Driver | No | 18 | 0.158 | 76 | 7 | 0.092 | 0 |
| SENP1 | SENP1 | Q9P0U3 | Sentrin-specific protease 1 | chr12 | GO:0006919 | Not Cancer Driver | No | 64 | 0.099 | 355 | 44 | 0.124 | 0 |
| SLC1A1 | SLC1A1 | P43005 | Excitatory amino acid transporter 3 | chr9 | GO:0006919 | Not Cancer Driver | No | 69 | 0.132 | 17 | 4 | 0.235 | 1 |
| SLC22A2 | SLC22A2 | O15244 | Solute carrier family 22 member 2 | chr6 | GO:0006919 | Not Cancer Driver | No | 126 | 0.227 | 31 | 11 | 0.355 | 0 |
| SMAD3 | SMAD3 | P84022 | Mothers against decapentaplegic homolog 3 | chr15 | GO:0006919 | Census, Compendium | Yes | 97 | 0.228 | 111 | 19 | 0.171 | 5 |
| SNCA_ENST00000506244 | SNCA | P37840 | Alpha-synuclein | chr4 | GO:0006919 | Not Cancer Driver | No | 21 | 0.15 | 107 | 13 | 0.121 | 5 |
| ST20_ENST00000562759 | ST20 | Q9HBF5 | Suppressor of tumorigenicity 20 protein | chr15 | GO:0006919 | Not Cancer Driver | No | 17 | 0.215 | 0 | 0 | 0.0 | 0 |
| TNF | TNF | P01375 | Tumor necrosis factor | chr6 | GO:0006919 | Not Cancer Driver | No | 24 | 0.103 | 45 | 3 | 0.067 | 0 |
| TNFSF15 | TNFSF15 | O95150 | Tumor necrosis factor ligand superfamily member 15 | chr9 | GO:0006919 | Not Cancer Driver | No | 41 | 0.163 | 49 | 12 | 0.245 | 0 |
| VCP | VCP | P55072 | Transitional endoplasmic reticulum ATPase | chr9 | GO:0006919 | Not Cancer Driver | No | 88 | 0.109 | 186 | 16 | 0.086 | 16 |
| XDH | XDH | P47989 | Xanthine dehydrogenase/oxidase | chr2 | GO:0006919 | Not Cancer Driver | No | 279 | 0.209 | 134 | 24 | 0.179 | 1 |