Filter in search result
Please select a valid state.

Total number of protein in "GO:0006915" GO term:  631

Identifier UniProt Gene UniProt Accession UniProt Name Chromosome GO term Database Cancer Driver Number of missense mutations Missense mutation per residues Number of disordered residues Number of mutations in disordered regions Disordered missense mutations per residues Number of OMIM mutation
ABL1_ENST00000318560 ABL1 P00519 Tyrosine-protein kinase ABL1 chr9 GO:0006915 Census, Compendium Yes 139 0.123 604 73 0.121 2
AC069368.1 AC069368.1 C9J4A7 PH domain-containing protein (Fragment) chr15 GO:0006915 Not Cancer Driver No 26 0.115 62 10 0.161 0
ADAM15 ADAM15 Q13444 Disintegrin and metalloproteinase domain-containing protein 15 chr1 GO:0006915 Not Cancer Driver No 104 0.121 213 29 0.136 0
ADAMTSL4_ENST00000369038 ADAMTSL4 Q6UY14 ADAMTS-like protein 4 chr1 GO:0006915 Not Cancer Driver No 156 0.145 563 78 0.139 0
ADARB1 ADARB1 P78563 Double-stranded RNA-specific editase 1 chr21 GO:0006915 Not Cancer Driver No 102 0.138 348 34 0.098 1
ADORA2A ADORA2A P29274 Adenosine receptor A2a chr22 GO:0006915 Not Cancer Driver No 61 0.148 93 11 0.118 0
ADRA1A_ENST00000380573 ADRA1A P35348 Alpha-1A adrenergic receptor chr8 GO:0006915 Not Cancer Driver No 130 0.279 40 8 0.2 0
AHCYL1 AHCYL1 O43865 S-adenosylhomocysteine hydrolase-like protein 1 chr1 GO:0006915 Not Cancer Driver No 58 0.109 108 10 0.093 0
AHR AHR P35869 Aryl hydrocarbon receptor chr7 GO:0006915 Not Cancer Driver No 129 0.152 351 75 0.214 0
AIFM1 AIFM1 O95831 Apoptosis-inducing factor 1, mitochondrial chrX GO:0006915 Not Cancer Driver No 88 0.144 166 22 0.133 11
AIM2 AIM2 O14862 Interferon-inducible protein AIM2 chr1 GO:0006915 Not Cancer Driver No 73 0.213 78 22 0.282 0
AIMP1_ENST00000442366 AIMP1 Q12904 Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 chr4 GO:0006915 Not Cancer Driver No 31 0.099 161 19 0.118 0
AIMP2 AIMP2 Q13155 Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 chr7 GO:0006915 Not Cancer Driver No 46 0.144 61 8 0.131 0
AKAP1_ENST00000539273 AKAP1 Q92667 A-kinase anchor protein 1, mitochondrial chr17 GO:0006915 Not Cancer Driver No 107 0.118 537 67 0.125 0
AKT1_ENST00000349310 AKT1 P31749 RAC-alpha serine/threonine-protein kinase chr14 GO:0006915 Census, Compendium Yes 108 0.225 158 24 0.152 4
AKT2 AKT2 P31751 RAC-beta serine/threonine-protein kinase chr19 GO:0006915 Census Yes 77 0.16 84 9 0.107 2
AKTIP_ENST00000570004 AKTIP Q9H8T0 AKT-interacting protein chr16 GO:0006915 Not Cancer Driver No 33 0.113 95 10 0.105 0
ALOX15B ALOX15B O15296 Polyunsaturated fatty acid lipoxygenase ALOX15B chr17 GO:0006915 Not Cancer Driver No 99 0.146 62 12 0.194 0
APAF1 APAF1 O14727 Apoptotic protease-activating factor 1 chr12 GO:0006915 Not Cancer Driver No 127 0.102 17 1 0.059 0
APBB1 APBB1 O00213 Amyloid beta precursor protein binding family B member 1 chr11 GO:0006915 Not Cancer Driver No 105 0.148 399 58 0.145 0
API5 API5 Q9BZZ5 Apoptosis inhibitor 5 chr11 GO:0006915 Not Cancer Driver No 65 0.124 92 10 0.109 0
APIP APIP Q96GX9 Methylthioribulose-1-phosphate dehydratase chr11 GO:0006915 Not Cancer Driver No 24 0.099 26 1 0.038 0
APLP1 APLP1 P51693 Amyloid beta precursor like protein 1 chr19 GO:0006915 Not Cancer Driver No 146 0.225 455 98 0.215 0
AREL1 AREL1 O15033 Apoptosis-resistant E3 ubiquitin protein ligase 1 chr14 GO:0006915 Not Cancer Driver No 104 0.126 92 10 0.109 0
ARF6 ARF6 P62330 ADP-ribosylation factor 6 chr14 GO:0006915 Not Cancer Driver No 18 0.103 5 0 0.0 0
ARHGEF6 ARHGEF6 Q15052 Rho guanine nucleotide exchange factor 6 chrX GO:0006915 Not Cancer Driver No 158 0.204 223 45 0.202 0
ARL6IP1 ARL6IP1 Q15041 ADP-ribosylation factor-like protein 6-interacting protein 1 chr16 GO:0006915 Not Cancer Driver No 35 0.172 9 1 0.111 0
ASAH2 ASAH2 Q9NR71 Neutral ceramidase chr10 GO:0006915 Not Cancer Driver No 71 0.091 140 24 0.171 0
ATCAY ATCAY Q86WG3 Caytaxin chr19 GO:0006915 Not Cancer Driver No 75 0.202 188 38 0.202 1
ATF2 ATF2 P15336 Cyclic AMP-dependent transcription factor ATF-2 chr2 GO:0006915 Not Cancer Driver No 65 0.129 451 58 0.129 0
ATG4D ATG4D Q86TL0 Cysteine protease ATG4D chr19 GO:0006915 Not Cancer Driver No 70 0.148 106 12 0.113 0
ATG5_ENST00000343245 ATG5 Q9H1Y0 Autophagy protein 5 chr6 GO:0006915 Not Cancer Driver No 40 0.145 25 6 0.24 1
ATP5F1A_ENST00000282050 ATP5F1A P25705 ATP synthase subunit alpha, mitochondrial chr18 GO:0006915 Not Cancer Driver No 66 0.119 23 5 0.217 2
AVEN AVEN Q9NQS1 Cell death regulator Aven chr15 GO:0006915 Not Cancer Driver No 39 0.108 315 33 0.105 0
AVP AVP P01185 Vasopressin-neurophysin 2-copeptin chr20 GO:0006915 Not Cancer Driver No 14 0.085 26 0 0.0 39
AXIN1 AXIN1 O15169 Axin-1 chr16 GO:0006915 Census, Compendium Yes 120 0.139 619 88 0.142 4
BABAM2_ENST00000342045 BABAM2 Q9NXR7 BRISC and BRCA1-A complex member 2 chr2 GO:0006915 Not Cancer Driver No 52 0.136 0 0 0.0 0
BAD_ENST00000309032 BAD Q92934 Bcl2-associated agonist of cell death chr11 GO:0006915 Not Cancer Driver No 14 0.083 163 14 0.086 0
BAG1 BAG1 Q99933 BAG family molecular chaperone regulator 1 chr9 GO:0006915 Not Cancer Driver No 29 0.084 195 9 0.046 0
BAG6 BAG6 P46379 Large proline-rich protein BAG6 chr6 GO:0006915 Not Cancer Driver No 98 0.087 861 79 0.092 0
BAK1 BAK1 Q16611 Bcl-2 homologous antagonist/killer chr6 GO:0006915 Not Cancer Driver No 38 0.18 58 9 0.155 0
BAX_ENST00000345358 BAX Q07812 Apoptosis regulator BAX chr19 GO:0006915 Census Yes 30 0.156 39 2 0.051 0
BBC3 BBC3 Q96PG8 Bcl-2-binding component 3, isoforms 3/4 chr19 GO:0006915 Not Cancer Driver No 20 0.077 253 20 0.079 0
BCAP29_ENST00000005259 BCAP29 Q9UHQ4 B-cell receptor-associated protein 29 chr7 GO:0006915 Not Cancer Driver No 33 0.137 96 15 0.156 0
BCAP31_ENST00000345046 BCAP31 P51572 B-cell receptor-associated protein 31 chrX GO:0006915 Not Cancer Driver No 37 0.15 104 14 0.135 0
BCL10 BCL10 O95999 B-cell lymphoma/leukemia 10 chr1 GO:0006915 Census, Compendium Yes 36 0.155 151 25 0.166 0
BCL2L1 BCL2L1 Q07817 Bcl-2-like protein 1 chr20 GO:0006915 Not Cancer Driver No 29 0.124 55 3 0.055 0
BCL2L10_ENST00000260442 BCL2L10 Q9HD36 Bcl-2-like protein 10 chr15 GO:0006915 Not Cancer Driver No 10 0.049 34 1 0.029 0
BCL2L11 BCL2L11 O43521 Bcl-2-like protein 11 chr2 GO:0006915 Not Cancer Driver No 42 0.212 130 17 0.131 0
BCL2L12 BCL2L12 Q9HB09 Bcl-2-like protein 12 chr19 GO:0006915 Census, Compendium Yes 40 0.12 132 10 0.076 0
BCL2L13_ENST00000317582 BCL2L13 Q9BXK5 Bcl-2-like protein 13 chr22 GO:0006915 Not Cancer Driver No 49 0.101 291 30 0.103 0
BCL2L14 BCL2L14 Q9BZR8 Apoptosis facilitator Bcl-2-like protein 14 chr12 GO:0006915 Not Cancer Driver No 29 0.089 40 4 0.1 0
BCL2L15 BCL2L15 Q5TBC7 Bcl-2-like protein 15 chr1 GO:0006915 Not Cancer Driver No 23 0.141 5 0 0.0 0
BCL2_ENST00000333681 BCL2 P10415 Apoptosis regulator Bcl-2 chr18 GO:0006915 Census, Compendium Yes 24 0.1 72 5 0.069 0
BCL7B_ENST00000223368 BCL7B Q9BQE9 B-cell CLL/lymphoma 7 protein family member B chr7 GO:0006915 Not Cancer Driver No 21 0.104 179 20 0.112 0
BCL7C_ENST00000215115 BCL7C Q8WUZ0 B-cell CLL/lymphoma 7 protein family member C chr16 GO:0006915 Not Cancer Driver No 28 0.129 209 25 0.12 0
BCLAF1 BCLAF1 Q9NYF8 Bcl-2-associated transcription factor 1 chr6 GO:0006915 Census, Compendium Yes 421 0.458 899 408 0.454 0
BECN1_ENST00000590099 BECN1 Q14457 Beclin-1 chr17 GO:0006915 Not Cancer Driver No 45 0.1 190 19 0.1 0
BEX2_ENST00000372677 BEX2 Q9BXY8 Protein BEX2 chrX GO:0006915 Not Cancer Driver No 23 0.18 105 13 0.124 0
BFAR BFAR Q9NZS9 Bifunctional apoptosis regulator chr16 GO:0006915 Not Cancer Driver No 56 0.124 30 1 0.033 0
BID_ENST00000551952 BID P55957 BH3-interacting domain death agonist chr22 GO:0006915 Not Cancer Driver No 23 0.118 74 9 0.122 0
BIK BIK Q13323 Bcl-2-interacting killer chr22 GO:0006915 Not Cancer Driver No 16 0.1 21 4 0.19 0
BIRC2 BIRC2 Q13490 Baculoviral IAP repeat-containing protein 2 chr11 GO:0006915 Not Cancer Driver No 69 0.112 83 9 0.108 0
BIRC3_ENST00000532808 BIRC3 Q13489 Baculoviral IAP repeat-containing protein 3 chr11 GO:0006915 Census, Compendium Yes 77 0.127 98 16 0.163 0
BIRC5_ENST00000350051 BIRC5 O15392 Baculoviral IAP repeat-containing protein 5 chr17 GO:0006915 Not Cancer Driver No 20 0.141 49 6 0.122 0
BIRC6 BIRC6 Q9NR09 Baculoviral IAP repeat-containing protein 6 chr2 GO:0006915 Census, Compendium Yes 640 0.132 1312 170 0.13 0
BIRC7 BIRC7 Q96CA5 Baculoviral IAP repeat-containing protein 7 chr20 GO:0006915 Not Cancer Driver No 52 0.174 136 22 0.162 0
BIRC8 BIRC8 Q96P09 Baculoviral IAP repeat-containing protein 8 chr19 GO:0006915 Not Cancer Driver No 79 0.335 39 10 0.256 0
BLID BLID Q8IZY5 BH3-like motif-containing cell death inducer chr11 GO:0006915 Not Cancer Driver No 25 0.231 0 0 0.0 0
BMF_ENST00000561360 BMF Q96LC9 Bcl-2-modifying factor chr15 GO:0006915 Not Cancer Driver No 22 0.12 94 9 0.096 0
BMP4 BMP4 P12644 Bone morphogenetic protein 4 chr14 GO:0006915 Not Cancer Driver No 86 0.211 142 26 0.183 5
BMPR2 BMPR2 Q13873 Bone morphogenetic protein receptor type-2 chr2 GO:0006915 Compendium Yes 141 0.136 601 70 0.116 19
BMX_ENST00000342014 BMX P51813 Cytoplasmic tyrosine-protein kinase BMX chrX GO:0006915 Not Cancer Driver No 106 0.157 172 27 0.157 0
BNIP1_ENST00000351486 BNIP1 Q12981 Vesicle transport protein SEC20 chr5 GO:0006915 Not Cancer Driver No 43 0.189 57 10 0.175 0
BNIP2_ENST00000607373 BNIP2 Q12982 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 chr15 GO:0006915 Not Cancer Driver No 28 0.089 144 18 0.125 0
BNIPL BNIPL Q7Z465 Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein chr1 GO:0006915 Not Cancer Driver No 45 0.126 182 23 0.126 0
BOK BOK Q9UMX3 Bcl-2-related ovarian killer protein chr2 GO:0006915 Not Cancer Driver No 7 0.033 0 0 0.0 0
BRAT1 BRAT1 Q6PJG6 BRCA1-associated ATM activator 1 chr7 GO:0006915 Not Cancer Driver No 112 0.136 101 13 0.129 0
BRMS1_ENST00000359957 BRMS1 Q9HCU9 Breast cancer metastasis-suppressor 1 chr11 GO:0006915 Not Cancer Driver No 42 0.171 115 18 0.157 0
BUB1 BUB1 O43683 Mitotic checkpoint serine/threonine-protein kinase BUB1 chr2 GO:0006915 Not Cancer Driver No 139 0.128 466 64 0.137 0
BUB1B BUB1B O60566 Mitotic checkpoint serine/threonine-protein kinase BUB1 beta chr15 GO:0006915 Census Yes 96 0.091 480 35 0.073 7
C19orf12 C19orf12 Q9NSK7 Protein C19orf12 chr19 GO:0006915 Not Cancer Driver No 23 0.151 7 0 0.0 15
C1D_ENST00000410067 C1D Q13901 Nuclear nucleic acid-binding protein C1D chr2 GO:0006915 Not Cancer Driver No 12 0.085 42 4 0.095 0
C1QBP C1QBP Q07021 Complement component 1 Q subcomponent-binding protein, mitochondrial chr17 GO:0006915 Not Cancer Driver No 14 0.05 103 6 0.058 2
C3orf38 C3orf38 Q5JPI3 Uncharacterized protein C3orf38 chr3 GO:0006915 Not Cancer Driver No 40 0.122 50 6 0.12 0
C6orf120 C6orf120 Q7Z4R8 UPF0669 protein C6orf120 chr6 GO:0006915 Not Cancer Driver No 19 0.099 27 3 0.111 0
CAAP1 CAAP1 Q9H8G2 Caspase activity and apoptosis inhibitor 1 chr9 GO:0006915 Not Cancer Driver No 28 0.078 234 18 0.077 0
CADM1_ENST00000452722 CADM1 Q9BY67 Cell adhesion molecule 1 chr11 GO:0006915 Not Cancer Driver No 106 0.24 103 28 0.272 0
CAPN10 CAPN10 Q9HC96 Calpain-10 chr2 GO:0006915 Not Cancer Driver No 87 0.129 52 6 0.115 0
CAPN3 CAPN3 P20807 Calpain-3 chr15 GO:0006915 Not Cancer Driver No 111 0.135 168 11 0.065 52
CARD14 CARD14 Q9BXL6 Caspase recruitment domain-containing protein 14 chr17 GO:0006915 Not Cancer Driver No 99 0.099 296 36 0.122 11
CARD6 CARD6 Q9BX69 Caspase recruitment domain-containing protein 6 chr5 GO:0006915 Not Cancer Driver No 203 0.196 500 85 0.17 0
CASP1 CASP1 P29466 Caspase-1 chr11 GO:0006915 Not Cancer Driver No 79 0.196 87 18 0.207 0
CASP10_ENST00000272879 CASP10 Q92851 Caspase-10 chr2 GO:0006915 Not Cancer Driver No 57 0.109 126 17 0.135 3
CASP12 CASP12 Q6UXS9 Inactive caspase-12 chr11 GO:0006915 Not Cancer Driver No 12 0.035 31 1 0.032 0
CASP2 CASP2 P42575 Caspase-2 chr7 GO:0006915 Not Cancer Driver No 63 0.139 42 12 0.286 0
CASP3 CASP3 P42574 Caspase-3 chr4 GO:0006915 Census Yes 32 0.116 62 5 0.081 0
CASP4 CASP4 P49662 Caspase-4 chr11 GO:0006915 Not Cancer Driver No 56 0.149 102 14 0.137 0
CASP5_ENST00000260315 CASP5 P51878 Caspase-5 chr11 GO:0006915 Not Cancer Driver No 103 0.237 61 17 0.279 0
CASP6 CASP6 P55212 Caspase-6 chr4 GO:0006915 Not Cancer Driver No 28 0.096 24 4 0.167 0
CASP7_ENST00000345633 CASP7 P55210 Caspase-7 chr10 GO:0006915 Not Cancer Driver No 38 0.125 73 10 0.137 0
CASP8_ENST00000432109 CASP8 Q14790 Caspase-8 chr2 GO:0006915 Census, Compendium Yes 142 0.296 106 12 0.113 1
CASP9 CASP9 P55211 Caspase-9 chr1 GO:0006915 Census Yes 49 0.118 71 7 0.099 0
CASR_ENST00000638421 CASR P41180 Extracellular calcium-sensing receptor chr3 GO:0006915 Not Cancer Driver No 304 0.282 189 60 0.317 108
CCAR1 CCAR1 Q8IX12 Cell division cycle and apoptosis regulator protein 1 chr10 GO:0006915 Not Cancer Driver No 145 0.126 771 76 0.099 0
CCN1 CCN1 O00622 CCN family member 1 chr1 GO:0006915 Not Cancer Driver No 33 0.087 12 0 0.0 0
CD14 CD14 P08571 Monocyte differentiation antigen CD14 chr5 GO:0006915 Not Cancer Driver No 42 0.112 60 5 0.083 0
CD2 CD2 P06729 T-cell surface antigen CD2 chr1 GO:0006915 Not Cancer Driver No 75 0.214 126 35 0.278 0
CD5L CD5L O43866 CD5 antigen-like chr1 GO:0006915 Not Cancer Driver No 145 0.418 33 13 0.394 0
CDCA7_ENST00000347703 CDCA7 Q9BWT1 Cell division cycle-associated protein 7 chr2 GO:0006915 Not Cancer Driver No 68 0.183 234 43 0.184 2
CDIP1 CDIP1 Q9H305 Cell death-inducing p53-target protein 1 chr16 GO:0006915 Not Cancer Driver No 10 0.048 119 7 0.059 0
CDK1 CDK1 P06493 Cyclin-dependent kinase 1 chr10 GO:0006915 Not Cancer Driver No 40 0.135 1 0 0.0 0
CDK11A CDK11A Q9UQ88 Cyclin-dependent kinase 11A chr1 GO:0006915 Not Cancer Driver No 66 0.084 485 44 0.091 0
CDK11B CDK11B P21127 Cyclin-dependent kinase 11B chr1 GO:0006915 Not Cancer Driver No 74 0.093 501 35 0.07 0
CEACAM5 CEACAM5 P06731 Carcinoembryonic antigen-related cell adhesion molecule 5 chr19 GO:0006915 Not Cancer Driver No 135 0.192 256 48 0.188 0
CEACAM6 CEACAM6 P40199 Carcinoembryonic antigen-related cell adhesion molecule 6 chr19 GO:0006915 Not Cancer Driver No 63 0.183 110 19 0.173 0
CFLAR CFLAR O15519 CASP8 and FADD-like apoptosis regulator chr2 GO:0006915 Not Cancer Driver No 40 0.083 44 2 0.045 0
CGB7_ENST00000377280 CGB7 P0DN87 Choriogonadotropin subunit beta 7 chr19 GO:0006915 Not Cancer Driver No 21 0.127 41 7 0.171 0
CGB8 CGB8 P0DN86 Choriogonadotropin subunit beta 3 chr19 GO:0006915 Not Cancer Driver No 9 0.055 41 2 0.049 0
CHEK1_ENST00000428830 CHEK1 O14757 Serine/threonine-protein kinase Chk1 chr11 GO:0006915 Not Cancer Driver No 58 0.122 86 16 0.186 0
CHI3L1 CHI3L1 P36222 Chitinase-3-like protein 1 chr1 GO:0006915 Not Cancer Driver No 66 0.172 24 5 0.208 0
CHIA_ENST00000343320 CHIA Q9BZP6 Acidic mammalian chitinase chr1 GO:0006915 Not Cancer Driver No 116 0.244 42 10 0.238 0
CHMP3 CHMP3 Q9Y3E7 Charged multivesicular body protein 3 chr2 GO:0006915 Not Cancer Driver No 25 0.113 137 13 0.095 0
CIAPIN1 CIAPIN1 Q6FI81 Anamorsin chr16 GO:0006915 Not Cancer Driver No 27 0.087 119 8 0.067 0
CIB1_ENST00000328649 CIB1 Q99828 Calcium and integrin-binding protein 1 chr15 GO:0006915 Not Cancer Driver No 24 0.126 6 1 0.167 0
CIDEA CIDEA O60543 Cell death activator CIDE-A chr18 GO:0006915 Not Cancer Driver No 43 0.196 32 3 0.094 0
CIDEB CIDEB Q9UHD4 Cell death activator CIDE-B chr14 GO:0006915 Not Cancer Driver No 19 0.087 23 1 0.043 0
CIDEC_ENST00000336832 CIDEC Q96AQ7 Cell death activator CIDE-3 chr3 GO:0006915 Not Cancer Driver No 27 0.113 49 3 0.061 0
CITED1_ENST00000246139 CITED1 Q99966 Cbp/p300-interacting transactivator 1 chrX GO:0006915 Not Cancer Driver No 24 0.124 166 21 0.127 0
CKAP2 CKAP2 Q8WWK9 Cytoskeleton-associated protein 2 chr13 GO:0006915 Not Cancer Driver No 72 0.105 522 57 0.109 0
CLC CLC Q05315 Galectin-10 chr19 GO:0006915 Not Cancer Driver No 29 0.204 0 0 0.0 0
CLPTM1L CLPTM1L Q96KA5 Cleft lip and palate transmembrane protein 1-like protein chr5 GO:0006915 Not Cancer Driver No 83 0.154 38 4 0.105 0
COL4A3 COL4A3 Q01955 Collagen alpha-3(IV) chain chr2 GO:0006915 Not Cancer Driver No 310 0.186 1433 277 0.193 13
COMP COMP P49747 Cartilage oligomeric matrix protein chr19 GO:0006915 Not Cancer Driver No 97 0.128 306 52 0.17 61
CRKL CRKL P46109 Crk-like protein chr22 GO:0006915 Not Cancer Driver No 38 0.125 160 25 0.156 0
CRYAB_ENST00000616970 CRYAB P02511 Alpha-crystallin B chain chr11 GO:0006915 Not Cancer Driver No 22 0.126 59 11 0.186 4
CSNK2A1_ENST00000400217 CSNK2A1 P68400 Casein kinase II subunit alpha chr20 GO:0006915 Not Cancer Driver No 71 0.182 75 8 0.107 4
CSNK2A2 CSNK2A2 P19784 Casein kinase II subunit alpha' chr16 GO:0006915 Not Cancer Driver No 43 0.123 13 1 0.077 0
CSRNP1 CSRNP1 Q96S65 Cysteine/serine-rich nuclear protein 1 chr3 GO:0006915 Not Cancer Driver No 71 0.121 312 33 0.106 0
CSRNP2 CSRNP2 Q9H175 Cysteine/serine-rich nuclear protein 2 chr12 GO:0006915 Not Cancer Driver No 64 0.118 319 38 0.119 0
CSRNP3_ENST00000342316 CSRNP3 Q8WYN3 Cysteine/serine-rich nuclear protein 3 chr2 GO:0006915 Not Cancer Driver No 113 0.193 395 71 0.18 0
CTNNBL1 CTNNBL1 Q8WYA6 Beta-catenin-like protein 1 chr20 GO:0006915 Not Cancer Driver No 72 0.128 158 24 0.152 0
CTSC CTSC P53634 Dipeptidyl peptidase 1 chr11 GO:0006915 Not Cancer Driver No 64 0.138 19 5 0.263 29
CTSH CTSH P09668 Pro-cathepsin H chr15 GO:0006915 Not Cancer Driver No 45 0.134 4 0 0.0 0
CTSL CTSL P07711 Procathepsin L chr9 GO:0006915 Not Cancer Driver No 47 0.141 34 4 0.118 0
CUL3 CUL3 Q13618 Cullin-3 chr2 GO:0006915 Census, Compendium Yes 123 0.16 167 23 0.138 3
CXCR3_ENST00000373693 CXCR3 P49682 C-X-C chemokine receptor type 3 chrX GO:0006915 Not Cancer Driver No 58 0.158 15 0 0.0 0
CXCR4_ENST00000241393 CXCR4 P61073 C-X-C chemokine receptor type 4 chr2 GO:0006915 Census, Compendium Yes 62 0.176 5 1 0.2 0
CYFIP2 CYFIP2 Q96F07 Cytoplasmic FMR1-interacting protein 2 chr5 GO:0006915 Not Cancer Driver No 211 0.165 86 11 0.128 3
DAB2 DAB2 P98082 Disabled homolog 2 chr5 GO:0006915 Not Cancer Driver No 144 0.187 680 125 0.184 0
DAB2IP_ENST00000408936 DAB2IP Q5VWQ8 Disabled homolog 2-interacting protein chr9 GO:0006915 Not Cancer Driver No 131 0.11 681 68 0.1 0
DAD1 DAD1 P61803 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 chr14 GO:0006915 Not Cancer Driver No 7 0.062 0 0 0.0 0
DAPK1_ENST00000622514 DAPK1 P53355 Death-associated protein kinase 1 chr9 GO:0006915 Not Cancer Driver No 193 0.135 114 11 0.096 0
DAPK2 DAPK2 Q9UIK4 Death-associated protein kinase 2 chr15 GO:0006915 Not Cancer Driver No 55 0.149 53 9 0.17 0
DAPK3_ENST00000301264 DAPK3 O43293 Death-associated protein kinase 3 chr19 GO:0006915 Not Cancer Driver No 56 0.123 82 7 0.085 0
DAP_ENST00000230895 DAP P51397 Death-associated protein 1 chr5 GO:0006915 Not Cancer Driver No 10 0.098 102 10 0.098 0
DCC DCC P43146 Netrin receptor DCC chr18 GO:0006915 Census, Compendium Yes 530 0.366 631 215 0.341 2
DDIAS DDIAS Q8IXT1 DNA damage-induced apoptosis suppressor protein chr11 GO:0006915 Not Cancer Driver No 125 0.125 370 59 0.159 0
DDIT4 DDIT4 Q9NX09 DNA damage-inducible transcript 4 protein chr10 GO:0006915 Not Cancer Driver No 20 0.086 87 9 0.103 0
DDX41 DDX41 Q9UJV9 Probable ATP-dependent RNA helicase DDX41 chr5 GO:0006915 Not Cancer Driver No 82 0.132 180 26 0.144 1
DFFA DFFA O00273 DNA fragmentation factor subunit alpha chr1 GO:0006915 Not Cancer Driver No 47 0.142 113 18 0.159 0
DHCR24 DHCR24 Q15392 Delta(24)-sterol reductase chr1 GO:0006915 Not Cancer Driver No 55 0.107 0 0 0.0 6
DIABLO DIABLO Q9NR28 Diablo IAP-binding mitochondrial protein chr12 GO:0006915 Not Cancer Driver No 62 0.259 54 8 0.148 1
DIO3 DIO3 P55073 Thyroxine 5-deiodinase chr14 GO:0006915 Not Cancer Driver No 88 0.289 71 18 0.254 0
DLC1 DLC1 Q96QB1 Rho GTPase-activating protein 7 chr8 GO:0006915 Not Cancer Driver No 331 0.217 922 237 0.257 0
DMPK_ENST00000291270 DMPK Q09013 Myotonin-protein kinase chr19 GO:0006915 Not Cancer Driver No 54 0.086 220 14 0.064 0
DNAJA3 DNAJA3 Q96EY1 DnaJ homolog subfamily A member 3, mitochondrial chr16 GO:0006915 Not Cancer Driver No 50 0.104 152 21 0.138 0
DNASE1_ENST00000246949 DNASE1 P24855 Deoxyribonuclease-1 chr16 GO:0006915 Not Cancer Driver No 24 0.085 0 0 0.0 0
DNMT3A DNMT3A Q9Y6K1 DNA (cytosine-5)-methyltransferase 3A chr2 GO:0006915 Census, Compendium Yes 194 0.213 371 59 0.159 16
DOCK1_ENST00000280333 DOCK1 Q14185 Dedicator of cytokinesis protein 1 chr10 GO:0006915 Not Cancer Driver No 240 0.129 360 52 0.144 0
DPEP1 DPEP1 P16444 Dipeptidase 1 chr16 GO:0006915 Not Cancer Driver No 54 0.131 41 6 0.146 0
DPF1_ENST00000456296 DPF1 Q92782 Zinc finger protein neuro-d4 chr19 GO:0006915 Not Cancer Driver No 32 0.083 85 7 0.082 0
DPF2_ENST00000528416 DPF2 Q92785 Zinc finger protein ubi-d4 chr11 GO:0006915 Not Cancer Driver No 67 0.171 179 30 0.168 5
DPP8_ENST00000559233 DPP8 Q6V1X1 Dipeptidyl peptidase 8 chr15 GO:0006915 Not Cancer Driver No 99 0.11 71 5 0.07 0
DRAM1 DRAM1 Q8N682 DNA damage-regulated autophagy modulator protein 1 chr12 GO:0006915 Not Cancer Driver No 25 0.105 0 0 0.0 0
DRAM2 DRAM2 Q6UX65 DNA damage-regulated autophagy modulator protein 2 chr1 GO:0006915 Not Cancer Driver No 26 0.098 0 0 0.0 3
DYNLL1_ENST00000242577 DYNLL1 P63167 Dynein light chain 1, cytoplasmic chr12 GO:0006915 Not Cancer Driver No 9 0.101 0 0 0.0 0
E2F1 E2F1 Q01094 Transcription factor E2F1 chr20 GO:0006915 Not Cancer Driver No 49 0.112 272 23 0.085 0
E2F2 E2F2 Q14209 Transcription factor E2F2 chr1 GO:0006915 Not Cancer Driver No 42 0.096 282 28 0.099 0
EAF2 EAF2 Q96CJ1 ELL-associated factor 2 chr3 GO:0006915 Not Cancer Driver No 31 0.119 199 22 0.111 0
EBAG9_ENST00000620557 EBAG9 O00559 Receptor-binding cancer antigen expressed on SiSo cells chr8 GO:0006915 Not Cancer Driver No 35 0.164 173 29 0.168 0
ECSCR ECSCR Q19T08 Endothelial cell-specific chemotaxis regulator chr5 GO:0006915 Not Cancer Driver No 5 0.024 127 3 0.024 0
EDAR EDAR Q9UNE0 Tumor necrosis factor receptor superfamily member EDAR chr2 GO:0006915 Not Cancer Driver No 81 0.181 116 20 0.172 18
EDNRA EDNRA P25101 Endothelin-1 receptor chr4 GO:0006915 Not Cancer Driver No 62 0.145 21 6 0.286 2
EFNA5 EFNA5 P52803 Ephrin-A5 chr5 GO:0006915 Not Cancer Driver No 34 0.149 25 6 0.24 0
EGLN3 EGLN3 Q9H6Z9 Prolyl hydroxylase EGLN3 chr14 GO:0006915 Not Cancer Driver No 33 0.138 13 0 0.0 0
EI24 EI24 O14681 Etoposide-induced protein 2.4 homolog chr11 GO:0006915 Not Cancer Driver No 28 0.082 12 1 0.083 0
ELMO1_ENST00000448602 ELMO1 Q92556 Engulfment and cell motility protein 1 chr7 GO:0006915 Not Cancer Driver No 199 0.274 98 22 0.224 0
ELMO2_ENST00000396391 ELMO2 Q96JJ3 Engulfment and cell motility protein 2 chr20 GO:0006915 Not Cancer Driver No 82 0.114 101 9 0.089 0
EMC4 EMC4 Q5J8M3 ER membrane protein complex subunit 4 chr15 GO:0006915 Not Cancer Driver No 15 0.082 17 2 0.118 0
EP300 EP300 Q09472 Histone acetyltransferase p300 chr22 GO:0006915 Census, Compendium Yes 334 0.138 1790 196 0.109 1
EPB41L3 EPB41L3 Q9Y2J2 Band 4.1-like protein 3 chr18 GO:0006915 Not Cancer Driver No 298 0.274 695 207 0.298 0
EPHA7 EPHA7 Q15375 Ephrin type-A receptor 7 chr6 GO:0006915 Census, Compendium Yes 280 0.281 71 15 0.211 0
EPO EPO P01588 Erythropoietin chr7 GO:0006915 Not Cancer Driver No 27 0.14 9 1 0.111 1
ERCC2 ERCC2 P18074 General transcription and DNA repair factor IIH helicase subunit XPD chr19 GO:0006915 Census, Compendium Yes 150 0.197 5 0 0.0 35
ERCC3 ERCC3 P19447 General transcription and DNA repair factor IIH helicase subunit XPB chr2 GO:0006915 Census, Compendium Yes 92 0.118 208 22 0.106 2
ESPL1 ESPL1 Q14674 Separin chr12 GO:0006915 Not Cancer Driver No 211 0.1 380 39 0.103 0
ETV6 ETV6 P41212 Transcription factor ETV6 chr12 GO:0006915 Census, Compendium Yes 98 0.217 251 46 0.183 3
EVA1A_ENST00000410071 EVA1A Q9H8M9 Protein eva-1 homolog A chr2 GO:0006915 Not Cancer Driver No 35 0.23 53 9 0.17 0
EXOC5 EXOC5 O00471 Exocyst complex component 5 chr14 GO:0006915 Not Cancer Driver No 59 0.083 57 4 0.07 0
FADD FADD Q13158 FAS-associated death domain protein chr11 GO:0006915 Not Cancer Driver No 26 0.125 45 10 0.222 1
FAF1 FAF1 Q9UNN5 FAS-associated factor 1 chr1 GO:0006915 Not Cancer Driver No 83 0.128 241 34 0.141 0
FAIM2 FAIM2 Q9BWQ8 Protein lifeguard 2 chr12 GO:0006915 Not Cancer Driver No 37 0.117 54 11 0.204 0
FAIM_ENST00000393035 FAIM Q9NVQ4 Fas apoptotic inhibitory molecule 1 chr3 GO:0006915 Not Cancer Driver No 20 0.112 1 0 0.0 0
FAM32A FAM32A Q9Y421 Protein FAM32A chr19 GO:0006915 Not Cancer Driver No 10 0.089 112 10 0.089 0
FAM3B FAM3B P58499 Protein FAM3B chr21 GO:0006915 Not Cancer Driver No 30 0.128 37 5 0.135 0
FAP FAP Q12884 Prolyl endopeptidase FAP chr2 GO:0006915 Not Cancer Driver No 158 0.208 6 2 0.333 0
FAS FAS P25445 Tumor necrosis factor receptor superfamily member 6 chr10 GO:0006915 Census, Compendium Yes 55 0.164 62 18 0.29 22
FASLG FASLG P48023 Tumor necrosis factor ligand superfamily member 6 chr1 GO:0006915 Not Cancer Driver No 65 0.231 94 18 0.191 1
FASTKD2_ENST00000402774 FASTKD2 Q9NYY8 FAST kinase domain-containing protein 2, mitochondrial chr2 GO:0006915 Not Cancer Driver No 74 0.104 30 2 0.067 0
FATE1 FATE1 Q969F0 Fetal and adult testis-expressed transcript protein chrX GO:0006915 Not Cancer Driver No 45 0.246 117 30 0.256 0
FBXO10 FBXO10 Q9UK96 F-box only protein 10 chr9 GO:0006915 Not Cancer Driver No 106 0.111 223 23 0.103 0
FEM1B FEM1B Q9UK73 Protein fem-1 homolog B chr15 GO:0006915 Not Cancer Driver No 69 0.11 33 3 0.091 0
FGF21 FGF21 Q9NSA1 Fibroblast growth factor 21 chr19 GO:0006915 Not Cancer Driver No 37 0.177 109 24 0.22 0
FGF4 FGF4 P08620 Fibroblast growth factor 4 chr11 GO:0006915 Not Cancer Driver No 16 0.078 21 3 0.143 0
FGFR2_ENST00000358487 FGFR2 P21802 Fibroblast growth factor receptor 2 chr10 GO:0006915 Census, Compendium Yes 238 0.29 228 44 0.193 72
FKBP8_ENST00000222308 FKBP8 Q14318 Peptidyl-prolyl cis-trans isomerase FKBP8 chr19 GO:0006915 Not Cancer Driver No 71 0.172 160 25 0.156 0
FOXO1 FOXO1 Q12778 Forkhead box protein O1 chr13 GO:0006915 Census, Compendium Yes 81 0.124 584 75 0.128 0
FXR1 FXR1 P51114 Fragile X mental retardation syndrome-related protein 1 chr3 GO:0006915 Not Cancer Driver No 88 0.142 312 53 0.17 0
FZD5 FZD5 Q13467 Frizzled-5 chr2 GO:0006915 Not Cancer Driver No 45 0.077 58 4 0.069 0
G2E3 G2E3 Q7L622 G2/M phase-specific E3 ubiquitin-protein ligase chr14 GO:0006915 Not Cancer Driver No 79 0.112 26 6 0.231 0
GADD45A GADD45A P24522 Growth arrest and DNA damage-inducible protein GADD45 alpha chr1 GO:0006915 Not Cancer Driver No 10 0.061 39 5 0.128 0
GADD45B GADD45B O75293 Growth arrest and DNA damage-inducible protein GADD45 beta chr19 GO:0006915 Not Cancer Driver No 9 0.056 14 0 0.0 0
GADD45G GADD45G O95257 Growth arrest and DNA damage-inducible protein GADD45 gamma chr9 GO:0006915 Not Cancer Driver No 13 0.082 20 2 0.1 0
GAS2 GAS2 O43903 Growth arrest-specific protein 2 chr11 GO:0006915 Not Cancer Driver No 73 0.233 92 16 0.174 0
GAS6 GAS6 Q14393 Growth arrest-specific protein 6 chr13 GO:0006915 Not Cancer Driver No 82 0.121 42 6 0.143 0
GDF6 GDF6 Q6KF10 Growth/differentiation factor 6 chr8 GO:0006915 Not Cancer Driver No 91 0.2 225 46 0.204 14
GHITM GHITM Q9H3K2 Growth hormone-inducible transmembrane protein chr10 GO:0006915 Not Cancer Driver No 50 0.145 8 0 0.0 0
GJB6_ENST00000644667 GJB6 O95452 Gap junction beta-6 protein chr13 GO:0006915 Not Cancer Driver No 42 0.161 12 4 0.333 4
GLI3 GLI3 P10071 Transcriptional activator GLI3 chr7 GO:0006915 Not Cancer Driver No 385 0.244 1352 327 0.242 7
GLRX2_ENST00000367439 GLRX2 Q9NS18 Glutaredoxin-2, mitochondrial chr1 GO:0006915 Not Cancer Driver No 12 0.073 10 1 0.1 0
GML GML Q99445 Glycosyl-phosphatidylinositol-anchored molecule-like protein chr8 GO:0006915 Not Cancer Driver No 49 0.31 12 6 0.5 0
GNGT1_ENST00000429473 GNGT1 P63211 Guanine nucleotide-binding protein G(T) subunit gamma-T1 chr7 GO:0006915 Not Cancer Driver No 14 0.189 25 4 0.16 0
GPR65 GPR65 Q8IYL9 Psychosine receptor chr14 GO:0006915 Not Cancer Driver No 70 0.208 0 0 0.0 0
GRAMD4_ENST00000361034 GRAMD4 Q6IC98 GRAM domain-containing protein 4 chr22 GO:0006915 Not Cancer Driver No 79 0.137 165 27 0.164 0
GREM1 GREM1 O60565 Gremlin-1 chr15 GO:0006915 Not Cancer Driver No 25 0.136 77 12 0.156 0
GRK5 GRK5 P34947 G protein-coupled receptor kinase 5 chr10 GO:0006915 Not Cancer Driver No 77 0.131 103 18 0.175 0
GSDMA GSDMA Q96QA5 Gasdermin-A chr17 GO:0006915 Not Cancer Driver No 67 0.151 87 15 0.172 0
GSN GSN P06396 Gelsolin chr9 GO:0006915 Not Cancer Driver No 76 0.097 316 28 0.089 2
GULP1 GULP1 Q9UBP9 PTB domain-containing engulfment adapter protein 1 chr2 GO:0006915 Not Cancer Driver No 38 0.125 148 19 0.128 0
GZMA GZMA P12544 Granzyme A chr5 GO:0006915 Not Cancer Driver No 70 0.267 5 1 0.2 0
GZMB GZMB P10144 Granzyme B chr14 GO:0006915 Not Cancer Driver No 49 0.198 103 23 0.223 0
GZMH GZMH P20718 Granzyme H chr14 GO:0006915 Not Cancer Driver No 47 0.191 50 14 0.28 0
GZMM GZMM P51124 Granzyme M chr19 GO:0006915 Not Cancer Driver No 25 0.097 12 1 0.083 0
HAND2 HAND2 P61296 Heart- and neural crest derivatives-expressed protein 2 chr4 GO:0006915 Not Cancer Driver No 47 0.217 124 29 0.234 0
HCAR2 HCAR2 Q8TDS4 Hydroxycarboxylic acid receptor 2 chr12 GO:0006915 Not Cancer Driver No 78 0.215 43 8 0.186 0
HIF3A HIF3A Q9Y2N7 Hypoxia-inducible factor 3-alpha chr19 GO:0006915 Not Cancer Driver No 146 0.218 361 94 0.26 0
HINT2 HINT2 Q9BX68 Adenosine 5'-monophosphoramidase HINT2 chr9 GO:0006915 Not Cancer Driver No 10 0.061 29 2 0.069 0
HIP1 HIP1 O00291 Huntingtin-interacting protein 1 chr7 GO:0006915 Census, Compendium Yes 137 0.132 510 70 0.137 0
HIP1R HIP1R O75146 Huntingtin-interacting protein 1-related protein chr12 GO:0006915 Not Cancer Driver No 94 0.088 524 34 0.065 0
HIPK1_ENST00000426820 HIPK1 Q86Z02 Homeodomain-interacting protein kinase 1 chr1 GO:0006915 Not Cancer Driver No 158 0.131 565 89 0.158 0
HIPK3 HIPK3 Q9H422 Homeodomain-interacting protein kinase 3 chr11 GO:0006915 Not Cancer Driver No 128 0.105 559 51 0.091 0
HTATIP2_ENST00000443524 HTATIP2 Q9BUP3 Oxidoreductase HTATIP2 chr11 GO:0006915 Not Cancer Driver No 22 0.091 14 0 0.0 0
HTT HTT P42858 Huntingtin chr4 GO:0006915 Not Cancer Driver No 336 0.107 666 69 0.104 2
IAPP_ENST00000539393 IAPP P10997 Islet amyloid polypeptide chr12 GO:0006915 Not Cancer Driver No 22 0.247 10 2 0.2 0
IER3 IER3 P46695 Radiation-inducible immediate-early gene IEX-1 chr6 GO:0006915 Not Cancer Driver No 5 0.032 106 4 0.038 0
IFI27L1 IFI27L1 Q96BM0 Interferon alpha-inducible protein 27-like protein 1 chr14 GO:0006915 Not Cancer Driver No 8 0.077 3 0 0.0 0
IFI27L2 IFI27L2 Q9H2X8 Interferon alpha-inducible protein 27-like protein 2 chr14 GO:0006915 Not Cancer Driver No 18 0.138 39 4 0.103 0
IFI27_ENST00000621160 IFI27 P40305 Interferon alpha-inducible protein 27, mitochondrial chr14 GO:0006915 Not Cancer Driver No 10 0.082 0 0 0.0 0
IFI6_ENST00000361157 IFI6 P09912 Interferon alpha-inducible protein 6 chr1 GO:0006915 Not Cancer Driver No 12 0.092 7 0 0.0 0
IFNA2 IFNA2 P01563 Interferon alpha-2 chr9 GO:0006915 Not Cancer Driver No 38 0.202 2 0 0.0 0
IFNG IFNG P01579 Interferon gamma chr12 GO:0006915 Not Cancer Driver No 51 0.307 23 6 0.261 0
IFT57 IFT57 Q9NWB7 Intraflagellar transport protein 57 homolog chr3 GO:0006915 Not Cancer Driver No 46 0.107 219 18 0.082 0
IGFBP3_ENST00000275521 IGFBP3 P17936 Insulin-like growth factor-binding protein 3 chr7 GO:0006915 Not Cancer Driver No 41 0.141 103 25 0.243 0
IKBKG_ENST00000611071 IKBKG Q9Y6K9 NF-kappa-B essential modulator chrX GO:0006915 Not Cancer Driver No 6 0.014 301 6 0.02 22
IL10 IL10 P22301 Interleukin-10 chr1 GO:0006915 Not Cancer Driver No 19 0.107 23 1 0.043 0
IL17A IL17A Q16552 Interleukin-17A chr6 GO:0006915 Not Cancer Driver No 52 0.335 56 21 0.375 0
IL19_ENST00000270218 IL19 Q9UHD0 Interleukin-19 chr1 GO:0006915 Not Cancer Driver No 16 0.09 0 0 0.0 0
IL1A IL1A P01583 Interleukin-1 alpha chr2 GO:0006915 Not Cancer Driver No 30 0.111 35 6 0.171 0
IL1B IL1B P01584 Interleukin-1 beta chr2 GO:0006915 Not Cancer Driver No 39 0.145 16 3 0.188 0
IL24_ENST00000294984 IL24 Q13007 Interleukin-24 chr1 GO:0006915 Not Cancer Driver No 35 0.17 0 0 0.0 0
IL2RA IL2RA P01589 Interleukin-2 receptor subunit alpha chr10 GO:0006915 Not Cancer Driver No 51 0.188 131 29 0.221 2
IL6 IL6 P05231 Interleukin-6 chr7 GO:0006915 Not Cancer Driver No 35 0.165 58 7 0.121 0
ING4 ING4 Q9UNL4 Inhibitor of growth protein 4 chr12 GO:0006915 Not Cancer Driver No 31 0.124 108 15 0.139 0
INPP5D INPP5D Q92835 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 chr2 GO:0006915 Not Cancer Driver No 176 0.148 578 90 0.156 0
IRF1 IRF1 P10914 Interferon regulatory factor 1 chr5 GO:0006915 Compendium Yes 49 0.151 228 31 0.136 2
IRF3_ENST00000597198 IRF3 Q14653 Interferon regulatory factor 3 chr19 GO:0006915 Not Cancer Driver No 36 0.084 204 21 0.103 1
ITCH ITCH Q96J02 E3 ubiquitin-protein ligase Itchy homolog chr20 GO:0006915 Not Cancer Driver No 95 0.105 335 42 0.125 0
ITGB2_ENST00000355153 ITGB2 P05107 Integrin beta-2 chr21 GO:0006915 Not Cancer Driver No 147 0.191 59 9 0.153 15
ITGB3BP_ENST00000271002 ITGB3BP Q13352 Centromere protein R chr1 GO:0006915 Not Cancer Driver No 19 0.107 122 14 0.115 0
JADE1_ENST00000512960 JADE1 Q6IE81 Protein Jade-1 chr4 GO:0006915 Not Cancer Driver No 94 0.112 409 47 0.115 0
JAG2 JAG2 Q9Y219 Protein jagged-2 chr14 GO:0006915 Not Cancer Driver No 126 0.102 158 24 0.152 0
JAK2 JAK2 O60674 Tyrosine-protein kinase JAK2 chr9 GO:0006915 Census, Compendium Yes 136 0.12 59 5 0.085 5
JTB JTB O76095 Protein JTB chr1 GO:0006915 Not Cancer Driver No 14 0.096 4 1 0.25 0
KANK2_ENST00000586659 KANK2 Q63ZY3 KN motif and ankyrin repeat domain-containing protein 2 chr19 GO:0006915 Not Cancer Driver No 107 0.126 531 71 0.134 3
KCNIP3 KCNIP3 Q9Y2W7 Calsenilin chr2 GO:0006915 Not Cancer Driver No 39 0.152 60 13 0.217 0
KDELR1 KDELR1 P24390 ER lumen protein-retaining receptor 1 chr19 GO:0006915 Not Cancer Driver No 32 0.151 0 0 0.0 0
KIF1B_ENST00000377086 KIF1B O60333 Kinesin-like protein KIF1B chr1 GO:0006915 Not Cancer Driver No 253 0.139 633 106 0.167 1
KLF11 KLF11 O14901 Krueppel-like factor 11 chr2 GO:0006915 Not Cancer Driver No 57 0.111 308 38 0.123 2
KLLN KLLN B2CW77 Killin chr10 GO:0006915 Not Cancer Driver No 7 0.039 104 5 0.048 0
KMT2A_ENST00000389506 KMT2A Q03164 Histone-lysine N-methyltransferase 2A chr11 GO:0006915 Census, Compendium Yes 446 0.112 3145 338 0.107 0
KREMEN1_ENST00000407188 KREMEN1 Q96MU8 Kremen protein 1 chr22 GO:0006915 Not Cancer Driver No 68 0.144 73 7 0.096 1
KRT18_ENST00000388837 KRT18 P05783 Keratin, type I cytoskeletal 18 chr12 GO:0006915 Not Cancer Driver No 57 0.133 179 21 0.117 4
KRT20 KRT20 P35900 Keratin, type I cytoskeletal 20 chr17 GO:0006915 Not Cancer Driver No 68 0.16 171 31 0.181 0
LALBA LALBA P00709 Alpha-lactalbumin chr12 GO:0006915 Not Cancer Driver No 21 0.148 0 0 0.0 0
LCN2_ENST00000277480 LCN2 P80188 Neutrophil gelatinase-associated lipocalin chr9 GO:0006915 Not Cancer Driver No 29 0.146 4 3 0.75 0
LEF1 LEF1 Q9UJU2 Lymphoid enhancer-binding factor 1 chr4 GO:0006915 Census Yes 64 0.16 370 57 0.154 0
LGALS1 LGALS1 P09382 Galectin-1 chr22 GO:0006915 Not Cancer Driver No 16 0.119 0 0 0.0 0
LGALS13 LGALS13 Q9UHV8 Galactoside-binding soluble lectin 13 chr19 GO:0006915 Not Cancer Driver No 42 0.302 0 0 0.0 0
LGALS14_ENST00000392052 LGALS14 Q8TCE9 Placental protein 13-like chr19 GO:0006915 Not Cancer Driver No 35 0.252 0 0 0.0 0
LGALS16 LGALS16 A8MUM7 Galectin-16 chr19 GO:0006915 Not Cancer Driver No 19 0.134 0 0 0.0 0
LGALS7B LGALS7B P47929 Galectin-7 chr19 GO:0006915 Not Cancer Driver No 14 0.103 54 5 0.093 0
LMBR1L LMBR1L Q6UX01 Protein LMBR1L chr12 GO:0006915 Not Cancer Driver No 57 0.117 4 0 0.0 0
LRP5 LRP5 O75197 Low-density lipoprotein receptor-related protein 5 chr11 GO:0006915 Not Cancer Driver No 253 0.157 188 28 0.149 55
LTA LTA P01374 Lymphotoxin-alpha chr6 GO:0006915 Not Cancer Driver No 37 0.18 20 5 0.25 0
LTBR LTBR P36941 Tumor necrosis factor receptor superfamily member 3 chr12 GO:0006915 Not Cancer Driver No 44 0.101 200 21 0.105 0
MAGEH1 MAGEH1 Q9H213 Melanoma-associated antigen H1 chrX GO:0006915 Not Cancer Driver No 44 0.201 98 14 0.143 0
MAGI3 MAGI3 Q5TCQ9 Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 chr1 GO:0006915 Not Cancer Driver No 154 0.104 1039 105 0.101 0
MAL MAL P21145 Myelin and lymphocyte protein chr2 GO:0006915 Not Cancer Driver No 21 0.137 0 0 0.0 0
MAP1S MAP1S Q66K74 Microtubule-associated protein 1S chr19 GO:0006915 Not Cancer Driver No 118 0.111 527 48 0.091 0
MAP2K4_ENST00000353533 MAP2K4 P45985 Dual specificity mitogen-activated protein kinase kinase 4 chr17 GO:0006915 Census, Compendium Yes 89 0.223 137 28 0.204 0
MAP2K6 MAP2K6 P52564 Dual specificity mitogen-activated protein kinase kinase 6 chr17 GO:0006915 Not Cancer Driver No 48 0.144 55 11 0.2 0
MAP2K7_ENST00000397979 MAP2K7 O14733 Dual specificity mitogen-activated protein kinase kinase 7 chr19 GO:0006915 Compendium Yes 89 0.212 144 20 0.139 0
MAP3K10 MAP3K10 Q02779 Mitogen-activated protein kinase kinase kinase 10 chr19 GO:0006915 Not Cancer Driver No 112 0.117 589 62 0.105 0
MAP3K5 MAP3K5 Q99683 Mitogen-activated protein kinase kinase kinase 5 chr6 GO:0006915 Not Cancer Driver No 197 0.143 242 29 0.12 0
MAP3K7 MAP3K7 O43318 Mitogen-activated protein kinase kinase kinase 7 chr6 GO:0006915 Not Cancer Driver No 104 0.172 333 66 0.198 6
MAP3K9_ENST00000554752 MAP3K9 P80192 Mitogen-activated protein kinase kinase kinase 9 chr14 GO:0006915 Not Cancer Driver No 167 0.151 684 104 0.152 0
MAPK14_ENST00000229794 MAPK14 Q16539 Mitogen-activated protein kinase 14 chr6 GO:0006915 Not Cancer Driver No 39 0.108 25 1 0.04 0
MAPK1_ENST00000398822 MAPK1 P28482 Mitogen-activated protein kinase 1 chr22 GO:0006915 Census, Compendium Yes 62 0.172 2 0 0.0 7
MAPK3 MAPK3 P27361 Mitogen-activated protein kinase 3 chr16 GO:0006915 Not Cancer Driver No 38 0.1 49 5 0.102 0
MCM2 MCM2 P49736 DNA replication licensing factor MCM2 chr3 GO:0006915 Not Cancer Driver No 104 0.115 275 38 0.138 1
MDM2_ENST00000539479 MDM2 Q00987 E3 ubiquitin-protein ligase Mdm2 chr12 GO:0006915 Census, Compendium Yes 56 0.114 297 37 0.125 0
MECOM_ENST00000494292 MECOM Q03112 Histone-lysine N-methyltransferase MECOM chr3 GO:0006915 Census, Compendium Yes 287 0.233 749 159 0.212 3
MEF2A_ENST00000354410 MEF2A Q02078 Myocyte-specific enhancer factor 2A chr15 GO:0006915 Not Cancer Driver No 62 0.122 454 56 0.123 0
MEF2C_ENST00000504921 MEF2C Q06413 Myocyte-specific enhancer factor 2C chr5 GO:0006915 Not Cancer Driver No 92 0.195 408 81 0.199 0
MEF2D MEF2D Q14814 Myocyte-specific enhancer factor 2D chr1 GO:0006915 Not Cancer Driver No 72 0.138 455 67 0.147 0
MEGF10_ENST00000503335 MEGF10 Q96KG7 Multiple epidermal growth factor-like domains protein 10 chr5 GO:0006915 Not Cancer Driver No 216 0.189 204 42 0.206 2
MELK MELK Q14680 Maternal embryonic leucine zipper kinase chr9 GO:0006915 Not Cancer Driver No 76 0.117 162 24 0.148 0
MFN2_ENST00000444836 MFN2 O95140 Mitofusin-2 chr1 GO:0006915 Not Cancer Driver No 80 0.106 81 9 0.111 20
MFSD10 MFSD10 Q14728 Major facilitator superfamily domain-containing protein 10 chr4 GO:0006915 Not Cancer Driver No 49 0.108 18 1 0.056 0
MIEN1_ENST00000394231 MIEN1 Q9BRT3 Migration and invasion enhancer 1 chr17 GO:0006915 Not Cancer Driver No 17 0.148 37 4 0.108 0
MINDY3 MINDY3 Q9H8M7 Ubiquitin carboxyl-terminal hydrolase MINDY-3 chr10 GO:0006915 Not Cancer Driver No 73 0.164 17 2 0.118 0
MRPL41 MRPL41 Q8IXM3 39S ribosomal protein L41, mitochondrial chr9 GO:0006915 Not Cancer Driver No 18 0.131 23 1 0.043 0
MRPS30 MRPS30 Q9NP92 39S ribosomal protein S30, mitochondrial chr5 GO:0006915 Not Cancer Driver No 54 0.123 53 10 0.189 0
MT3 MT3 P25713 Metallothionein-3 chr16 GO:0006915 Not Cancer Driver No 7 0.103 0 0 0.0 0
MTCH1 MTCH1 Q9NZJ7 Mitochondrial carrier homolog 1 chr6 GO:0006915 Not Cancer Driver No 31 0.08 102 2 0.02 0
MTFP1 MTFP1 Q9UDX5 Mitochondrial fission process protein 1 chr22 GO:0006915 Not Cancer Driver No 18 0.108 18 2 0.111 0
MTOR MTOR P42345 Serine/threonine-protein kinase mTOR chr1 GO:0006915 Census, Compendium Yes 379 0.149 296 37 0.125 18
MUL1 MUL1 Q969V5 Mitochondrial ubiquitin ligase activator of NFKB 1 chr1 GO:0006915 Not Cancer Driver No 48 0.136 16 2 0.125 0
MX1_ENST00000398598 MX1 P20591 Interferon-induced GTP-binding protein Mx1 chr21 GO:0006915 Not Cancer Driver No 88 0.133 74 10 0.135 0
MYC_ENST00000377970 MYC P01106 Myc proto-oncogene protein chr8 GO:0006915 Census, Compendium Yes 80 0.182 299 46 0.154 0
MYD88_ENST00000396334 MYD88 Q99836 Myeloid differentiation primary response protein MyD88 chr3 GO:0006915 Census, Compendium Yes 37 0.125 47 1 0.021 2
MYDGF MYDGF Q969H8 Myeloid-derived growth factor chr19 GO:0006915 Not Cancer Driver No 23 0.133 26 4 0.154 0
MZB1 MZB1 Q8WU39 Marginal zone B- and B1-cell-specific protein chr5 GO:0006915 Not Cancer Driver No 15 0.079 75 9 0.12 0
NAIP_ENST00000194097 NAIP Q13075 Baculoviral IAP repeat-containing protein 1 chr5 GO:0006915 Not Cancer Driver No 39 0.028 67 4 0.06 0
NCF1 NCF1 P14598 Neutrophil cytosol factor 1 chr7 GO:0006915 Not Cancer Driver No 37 0.095 181 12 0.066 1
NCKAP1_ENST00000361354 NCKAP1 Q9Y2A7 Nck-associated protein 1 chr2 GO:0006915 Not Cancer Driver No 129 0.114 44 3 0.068 0
NEK6_ENST00000545174 NEK6 Q9HC98 Serine/threonine-protein kinase Nek6 chr9 GO:0006915 Not Cancer Driver No 31 0.099 36 0 0.0 0
NFKB1_ENST00000505458 NFKB1 P19838 Nuclear factor NF-kappa-B p105 subunit chr4 GO:0006915 Not Cancer Driver No 104 0.107 344 38 0.11 0
NFKBIA NFKBIA P25963 NF-kappa-B inhibitor alpha chr14 GO:0006915 Compendium Yes 37 0.117 102 9 0.088 1
NGB NGB Q9NPG2 Neuroglobin chr14 GO:0006915 Not Cancer Driver No 20 0.132 3 0 0.0 0
NHLH2_ENST00000320238 NHLH2 Q02577 Helix-loop-helix protein 2 chr1 GO:0006915 Not Cancer Driver No 19 0.141 83 8 0.096 0
NISCH_ENST00000479054 NISCH Q9Y2I1 Nischarin chr3 GO:0006915 Not Cancer Driver No 160 0.106 418 43 0.103 0
NKX2-5 NKX2-5 P52952 Homeobox protein Nkx-2.5 chr5 GO:0006915 Not Cancer Driver No 48 0.148 181 22 0.122 55
NLRC4_ENST00000360906 NLRC4 Q9NPP4 NLR family CARD domain-containing protein 4 chr2 GO:0006915 Not Cancer Driver No 205 0.2 15 2 0.133 3
NLRP1_ENST00000572272 NLRP1 Q9C000 NACHT, LRR and PYD domains-containing protein 1 chr17 GO:0006915 Not Cancer Driver No 222 0.151 340 65 0.191 6
NLRP2 NLRP2 Q9NX02 NACHT, LRR and PYD domains-containing protein 2 chr19 GO:0006915 Not Cancer Driver No 257 0.242 60 15 0.25 0
NLRP3_ENST00000391828 NLRP3 Q96P20 NACHT, LRR and PYD domains-containing protein 3 chr1 GO:0006915 Not Cancer Driver No 339 0.327 64 33 0.516 37
NME3 NME3 Q13232 Nucleoside diphosphate kinase 3 chr16 GO:0006915 Not Cancer Driver No 10 0.059 4 0 0.0 0
NME6_ENST00000415053 NME6 O75414 Nucleoside diphosphate kinase 6 chr3 GO:0006915 Not Cancer Driver No 23 0.124 22 3 0.136 0
NOA1 NOA1 Q8NC60 Nitric oxide-associated protein 1 chr4 GO:0006915 Not Cancer Driver No 74 0.106 225 25 0.111 0
NOC2L NOC2L Q9Y3T9 Nucleolar complex protein 2 homolog chr1 GO:0006915 Not Cancer Driver No 77 0.103 281 31 0.11 0
NOD1 NOD1 Q9Y239 Nucleotide-binding oligomerization domain-containing protein 1 chr7 GO:0006915 Not Cancer Driver No 130 0.136 38 7 0.184 0
NOL3_ENST00000268605 NOL3 O60936 Nucleolar protein 3 chr16 GO:0006915 Not Cancer Driver No 20 0.096 179 17 0.095 2
NOTCH1 NOTCH1 P46531 Neurogenic locus notch homolog protein 1 chr9 GO:0006915 Census, Compendium Yes 363 0.142 686 87 0.127 3
NOTCH2 NOTCH2 Q04721 Neurogenic locus notch homolog protein 2 chr1 GO:0006915 Census, Compendium Yes 282 0.114 630 77 0.122 1
NOX5 NOX5 Q96PH1 NADPH oxidase 5 chr15 GO:0006915 Not Cancer Driver No 118 0.154 95 9 0.095 0
NR3C1_ENST00000343796 NR3C1 P04150 Glucocorticoid receptor chr5 GO:0006915 Not Cancer Driver No 92 0.118 362 37 0.102 12
NR4A1_ENST00000394825 NR4A1 P22736 Nuclear receptor subfamily 4 group A member 1 chr12 GO:0006915 Not Cancer Driver No 62 0.104 252 24 0.095 0
NSG1_ENST00000513555 NSG1 P42857 Neuronal vesicle trafficking-associated protein 1 chr4 GO:0006915 Not Cancer Driver No 36 0.195 29 9 0.31 0
NTN1 NTN1 O95631 Netrin-1 chr17 GO:0006915 Not Cancer Driver No 57 0.094 66 4 0.061 2
NUDT2_ENST00000346365 NUDT2 P50583 Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] chr9 GO:0006915 Not Cancer Driver No 16 0.109 24 1 0.042 0
OGT OGT O15294 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit chrX GO:0006915 Not Cancer Driver No 156 0.149 89 16 0.18 2
OPA1_ENST00000392438 OPA1 O60313 Dynamin-like 120 kDa protein, mitochondrial chr3 GO:0006915 Not Cancer Driver No 114 0.119 131 17 0.13 60
P2RX1 P2RX1 P51575 P2X purinoceptor 1 chr17 GO:0006915 Not Cancer Driver No 59 0.148 14 1 0.071 0
PACS2_ENST00000325438 PACS2 Q86VP3 Phosphofurin acidic cluster sorting protein 2 chr14 GO:0006915 Not Cancer Driver No 122 0.137 460 59 0.128 1
PAEP_ENST00000277508 PAEP P09466 Glycodelin chr9 GO:0006915 Not Cancer Driver No 23 0.128 3 0 0.0 0
PAK1_ENST00000356341 PAK1 Q13153 Serine/threonine-protein kinase PAK 1 chr11 GO:0006915 Not Cancer Driver No 57 0.105 299 30 0.1 2
PAK2 PAK2 Q13177 Serine/threonine-protein kinase PAK 2 chr3 GO:0006915 Compendium Yes 89 0.17 242 49 0.202 0
PAK4 PAK4 O96013 Serine/threonine-protein kinase PAK 4 chr19 GO:0006915 Not Cancer Driver No 58 0.098 340 33 0.097 0
PAK5 PAK5 Q9P286 Serine/threonine-protein kinase PAK 5 chr20 GO:0006915 Not Cancer Driver No 226 0.314 407 123 0.302 0
PAK6_ENST00000260404 PAK6 Q9NQU5 Serine/threonine-protein kinase PAK 6 chr15 GO:0006915 Not Cancer Driver No 82 0.12 398 52 0.131 0
PARP1 PARP1 P09874 Poly [ADP-ribose] polymerase 1 chr1 GO:0006915 Not Cancer Driver No 119 0.117 320 34 0.106 0
PAWR PAWR Q96IZ0 PRKC apoptosis WT1 regulator protein chr12 GO:0006915 Not Cancer Driver No 35 0.103 327 33 0.101 0
PAX3_ENST00000350526 PAX3 P23760 Paired box protein Pax-3 chr2 GO:0006915 Census Yes 113 0.236 391 95 0.243 28
PCSK9 PCSK9 Q8NBP7 Proprotein convertase subtilisin/kexin type 9 chr1 GO:0006915 Not Cancer Driver No 86 0.124 148 27 0.182 9
PDCD1 PDCD1 Q15116 Programmed cell death protein 1 chr2 GO:0006915 Not Cancer Driver No 56 0.194 141 37 0.262 0
PDCD2 PDCD2 Q16342 Programmed cell death protein 2 chr6 GO:0006915 Not Cancer Driver No 32 0.093 42 6 0.143 0
PDCD4 PDCD4 Q53EL6 Programmed cell death protein 4 chr10 GO:0006915 Not Cancer Driver No 57 0.122 187 32 0.171 0
PDCD5 PDCD5 O14737 Programmed cell death protein 5 chr19 GO:0006915 Not Cancer Driver No 15 0.12 91 7 0.077 0
PDCD6IP_ENST00000307296 PDCD6IP Q8WUM4 Programmed cell death 6-interacting protein chr3 GO:0006915 Not Cancer Driver No 85 0.098 272 22 0.081 0
PDCD7 PDCD7 Q8N8D1 Programmed cell death protein 7 chr15 GO:0006915 Not Cancer Driver No 47 0.097 275 15 0.055 0
PDCL3 PDCL3 Q9H2J4 Phosducin-like protein 3 chr2 GO:0006915 Not Cancer Driver No 48 0.201 73 13 0.178 0
PDE1B PDE1B Q01064 Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B chr12 GO:0006915 Not Cancer Driver No 114 0.213 132 30 0.227 0
PDE6B PDE6B P35913 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta chr4 GO:0006915 Not Cancer Driver No 144 0.169 44 9 0.205 13
PEA15_ENST00000360472 PEA15 Q15121 Astrocytic phosphoprotein PEA-15 chr1 GO:0006915 Not Cancer Driver No 12 0.092 35 5 0.143 0
PEG10_ENST00000617526 PEG10 Q86TG7 Retrotransposon-derived protein PEG10 chr7 GO:0006915 Not Cancer Driver No 94 0.133 246 47 0.191 0
PEG3 PEG3 Q9GZU2 Paternally-expressed gene 3 protein chr19 GO:0006915 Compendium Yes 595 0.375 1067 404 0.379 0
PHLDA1_ENST00000619060 PHLDA1 Q8WV24 Pleckstrin homology-like domain family A member 1 chr12 GO:0006915 Not Cancer Driver No 51 0.127 311 42 0.135 0
PHLDA2_ENST00000645523 PHLDA2 Q53GA4 Pleckstrin homology-like domain family A member 2 chr11 GO:0006915 Not Cancer Driver No 12 0.079 58 2 0.034 0
PHLPP1 PHLPP1 O60346 PH domain leucine-rich repeat-containing protein phosphatase 1 chr18 GO:0006915 Not Cancer Driver No 134 0.078 744 29 0.039 0
PIDD1 PIDD1 Q9HB75 p53-induced death domain-containing protein 1 chr11 GO:0006915 Not Cancer Driver No 93 0.102 137 14 0.102 0
PIK3CA PIK3CA P42336 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform chr3 GO:0006915 Census, Compendium Yes 1669 1.563 38 11 0.289 30
PIK3CG PIK3CG P48736 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform chr7 GO:0006915 Not Cancer Driver No 318 0.289 121 39 0.322 0
PIM1 PIM1 P11309 Serine/threonine-protein kinase pim-1 chr6 GO:0006915 Census, Compendium Yes 71 0.227 27 8 0.296 0
PIM2 PIM2 Q9P1W9 Serine/threonine-protein kinase pim-2 chrX GO:0006915 Not Cancer Driver No 43 0.138 47 10 0.213 0
PIM3 PIM3 Q86V86 Serine/threonine-protein kinase pim-3 chr22 GO:0006915 Not Cancer Driver No 24 0.074 9 0 0.0 0
PKN1_ENST00000242783 PKN1 Q16512 Serine/threonine-protein kinase N1 chr19 GO:0006915 Not Cancer Driver No 120 0.127 459 54 0.118 0
PKN2 PKN2 Q16513 Serine/threonine-protein kinase N2 chr1 GO:0006915 Not Cancer Driver No 123 0.125 415 48 0.116 0
PLAGL1_ENST00000367571 PLAGL1 Q9UM63 Zinc finger protein PLAGL1 chr6 GO:0006915 Not Cancer Driver No 49 0.106 217 24 0.111 0
PLEKHF1 PLEKHF1 Q96S99 Pleckstrin homology domain-containing family F member 1 chr19 GO:0006915 Not Cancer Driver No 30 0.108 65 10 0.154 0
PLEKHO2 PLEKHO2 Q8TD55 Pleckstrin homology domain-containing family O member 2 chr15 GO:0006915 Not Cancer Driver No 61 0.124 402 56 0.139 0
PLK3 PLK3 Q9H4B4 Serine/threonine-protein kinase PLK3 chr1 GO:0006915 Not Cancer Driver No 75 0.116 202 15 0.074 0
PLSCR1 PLSCR1 O15162 Phospholipid scramblase 1 chr3 GO:0006915 Not Cancer Driver No 43 0.135 92 13 0.141 0
PLSCR3 PLSCR3 Q9NRY6 Phospholipid scramblase 3 chr17 GO:0006915 Not Cancer Driver No 30 0.102 62 5 0.081 0
PMAIP1 PMAIP1 Q13794 Phorbol-12-myristate-13-acetate-induced protein 1 chr18 GO:0006915 Not Cancer Driver No 2 0.037 23 1 0.043 0
PPARD_ENST00000360694 PPARD Q03181 Peroxisome proliferator-activated receptor delta chr6 GO:0006915 Not Cancer Driver No 72 0.163 69 7 0.101 0
PPIA PPIA P62937 Peptidyl-prolyl cis-trans isomerase A chr7 GO:0006915 Not Cancer Driver No 11 0.067 24 3 0.125 0
PPID PPID Q08752 Peptidyl-prolyl cis-trans isomerase D chr4 GO:0006915 Not Cancer Driver No 36 0.097 94 9 0.096 0
PPP1R13L_ENST00000360957 PPP1R13L Q8WUF5 RelA-associated inhibitor chr19 GO:0006915 Not Cancer Driver No 117 0.141 657 90 0.137 0
PPP1R15A PPP1R15A O75807 Protein phosphatase 1 regulatory subunit 15A chr19 GO:0006915 Not Cancer Driver No 83 0.123 628 72 0.115 0
PPP2CA PPP2CA P67775 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform chr5 GO:0006915 Not Cancer Driver No 41 0.133 12 1 0.083 8
PPP2R1A PPP2R1A P30153 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform chr19 GO:0006915 Census, Compendium Yes 179 0.304 0 0 0.0 4
PPP2R1B_ENST00000527614 PPP2R1B P30154 Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform chr11 GO:0006915 Not Cancer Driver No 72 0.12 17 1 0.059 0
PPP2R2B_ENST00000394409 PPP2R2B Q00005 Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform chr5 GO:0006915 Not Cancer Driver No 101 0.228 76 22 0.289 0
PRAME_ENST00000402697 PRAME P78395 Melanoma antigen preferentially expressed in tumors chr22 GO:0006915 Not Cancer Driver No 95 0.187 10 1 0.1 0
PRDX3 PRDX3 P30048 Thioredoxin-dependent peroxide reductase, mitochondrial chr10 GO:0006915 Not Cancer Driver No 23 0.09 23 3 0.13 0
PRDX5 PRDX5 P30044 Peroxiredoxin-5, mitochondrial chr11 GO:0006915 Not Cancer Driver No 22 0.103 0 0 0.0 0
PRELID1 PRELID1 Q9Y255 PRELI domain-containing protein 1, mitochondrial chr5 GO:0006915 Not Cancer Driver No 21 0.096 44 2 0.045 0
PRF1_ENST00000373209 PRF1 P14222 Perforin-1 chr10 GO:0006915 Census, Compendium Yes 122 0.22 145 36 0.248 8
PRKCB_ENST00000321728 PRKCB P05771 Protein kinase C beta type chr16 GO:0006915 Census, Compendium Yes 205 0.306 148 40 0.27 0
PRKCD_ENST00000330452 PRKCD Q05655 Protein kinase C delta type chr3 GO:0006915 Compendium Yes 79 0.117 43 9 0.209 0
PRKCE PRKCE Q02156 Protein kinase C epsilon type chr2 GO:0006915 Not Cancer Driver No 107 0.145 170 26 0.153 0
PRKD1_ENST00000616995 PRKD1 Q15139 Serine/threonine-protein kinase D1 chr14 GO:0006915 Census Yes 201 0.22 189 33 0.175 2
PRUNE2 PRUNE2 Q8WUY3 Protein prune homolog 2 chr9 GO:0006915 Not Cancer Driver No 572 0.185 2506 465 0.186 0
PSMD10 PSMD10 O75832 26S proteasome non-ATPase regulatory subunit 10 chrX GO:0006915 Not Cancer Driver No 20 0.088 53 5 0.094 0
PSME3_ENST00000590720 PSME3 P61289 Proteasome activator complex subunit 3 chr17 GO:0006915 Not Cancer Driver No 20 0.079 25 5 0.2 0
PTEN PTEN P60484 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN chr10 GO:0006915 Census, Compendium Yes 505 1.253 76 4 0.053 41
PTK2B_ENST00000346049 PTK2B Q14289 Protein-tyrosine kinase 2-beta chr8 GO:0006915 Not Cancer Driver No 161 0.16 261 37 0.142 0
PTPRH PTPRH Q9HD43 Receptor-type tyrosine-protein phosphatase H chr19 GO:0006915 Not Cancer Driver No 228 0.204 474 74 0.156 0
PTRH2_ENST00000470557 PTRH2 Q9Y3E5 Peptidyl-tRNA hydrolase 2, mitochondrial chr17 GO:0006915 Not Cancer Driver No 14 0.078 19 2 0.105 1
PUF60 PUF60 Q9UHX1 Poly(U)-binding-splicing factor PUF60 chr8 GO:0006915 Not Cancer Driver No 56 0.1 214 14 0.065 1
PYCARD PYCARD Q9ULZ3 Apoptosis-associated speck-like protein containing a CARD chr16 GO:0006915 Not Cancer Driver No 16 0.082 39 4 0.103 0
RABEP1 RABEP1 Q15276 Rab GTPase-binding effector protein 1 chr17 GO:0006915 Census, Compendium Yes 81 0.094 520 57 0.11 0
RACK1 RACK1 P63244 Receptor of activated protein C kinase 1 chr5 GO:0006915 Not Cancer Driver No 34 0.107 13 0 0.0 0
RAD21 RAD21 O60216 Double-strand-break repair protein rad21 homolog chr8 GO:0006915 Census, Compendium Yes 115 0.182 421 74 0.176 3
RAF1 RAF1 P04049 RAF proto-oncogene serine/threonine-protein kinase chr3 GO:0006915 Census, Compendium Yes 89 0.137 169 38 0.225 22
RALB RALB P11234 Ras-related protein Ral-B chr2 GO:0006915 Not Cancer Driver No 36 0.175 35 5 0.143 0
RASSF5 RASSF5 Q8WWW0 Ras association domain-containing protein 5 chr1 GO:0006915 Not Cancer Driver No 37 0.089 183 11 0.06 0
RASSF6 RASSF6 Q6ZTQ3 Ras association domain-containing protein 6 chr4 GO:0006915 Not Cancer Driver No 53 0.144 74 10 0.135 0
RASSF7 RASSF7 Q02833 Ras association domain-containing protein 7 chr11 GO:0006915 Not Cancer Driver No 28 0.075 278 19 0.068 0
RB1 RB1 P06400 Retinoblastoma-associated protein chr13 GO:0006915 Census, Compendium Yes 140 0.151 282 32 0.113 22
RBM5 RBM5 P52756 RNA-binding protein 5 chr3 GO:0006915 Not Cancer Driver No 94 0.115 537 67 0.125 0
RELT RELT Q969Z4 Tumor necrosis factor receptor superfamily member 19L chr11 GO:0006915 Not Cancer Driver No 48 0.112 239 18 0.075 0
RFFL_ENST00000394597 RFFL Q8WZ73 E3 ubiquitin-protein ligase rififylin chr17 GO:0006915 Not Cancer Driver No 50 0.138 150 21 0.14 0
RFK RFK Q969G6 Riboflavin kinase chr9 GO:0006915 Not Cancer Driver No 15 0.097 1 0 0.0 0
RHBDD1 RHBDD1 Q8TEB9 Rhomboid-related protein 4 chr2 GO:0006915 Not Cancer Driver No 38 0.121 69 9 0.13 0
RHOB RHOB P62745 Rho-related GTP-binding protein RhoB chr2 GO:0006915 Not Cancer Driver No 52 0.265 19 2 0.105 0
RIPK1_ENST00000380409 RIPK1 Q13546 Receptor-interacting serine/threonine-protein kinase 1 chr6 GO:0006915 Compendium Yes 82 0.122 277 39 0.141 4
RIPK2 RIPK2 O43353 Receptor-interacting serine/threonine-protein kinase 2 chr8 GO:0006915 Not Cancer Driver No 63 0.117 143 20 0.14 0
RMDN3 RMDN3 Q96TC7 Regulator of microtubule dynamics protein 3 chr15 GO:0006915 Not Cancer Driver No 45 0.096 196 17 0.087 0
RNF130 RNF130 Q86XS8 E3 ubiquitin-protein ligase RNF130 chr5 GO:0006915 Not Cancer Driver No 45 0.107 43 5 0.116 0
RNF144B RNF144B Q7Z419 E3 ubiquitin-protein ligase RNF144B chr6 GO:0006915 Not Cancer Driver No 32 0.106 4 1 0.25 0
RNF152 RNF152 Q8N8N0 E3 ubiquitin-protein ligase RNF152 chr18 GO:0006915 Not Cancer Driver No 61 0.3 34 11 0.324 0
RNF183_ENST00000297894 RNF183 Q96D59 E3 ubiquitin-protein ligase RNF183 chr9 GO:0006915 Not Cancer Driver No 22 0.115 29 1 0.034 0
RNF216_ENST00000425013 RNF216 Q9NWF9 E3 ubiquitin-protein ligase RNF216 chr7 GO:0006915 Not Cancer Driver No 108 0.125 415 57 0.137 2
RNF34_ENST00000361234 RNF34 Q969K3 E3 ubiquitin-protein ligase RNF34 chr12 GO:0006915 Not Cancer Driver No 30 0.081 112 7 0.062 0
ROBO2_ENST00000461745 ROBO2 Q9HCK4 Roundabout homolog 2 chr3 GO:0006915 Census Yes 407 0.295 874 259 0.296 2
ROCK1 ROCK1 Q13464 Rho-associated protein kinase 1 chr18 GO:0006915 Not Cancer Driver No 184 0.136 780 103 0.132 0
RPS3_ENST00000527446 RPS3 P23396 40S ribosomal protein S3 chr11 GO:0006915 Not Cancer Driver No 22 0.091 48 4 0.083 0
RPS6 RPS6 P62753 40S ribosomal protein S6 chr9 GO:0006915 Not Cancer Driver No 38 0.153 150 25 0.167 0
RPS6KA1_ENST00000374168 RPS6KA1 Q15418 Ribosomal protein S6 kinase alpha-1 chr1 GO:0006915 Not Cancer Driver No 94 0.128 178 32 0.18 0
RPS6KA2_ENST00000265678 RPS6KA2 Q15349 Ribosomal protein S6 kinase alpha-2 chr6 GO:0006915 Not Cancer Driver No 133 0.181 91 15 0.165 0
RPS6KA3_ENST00000379565 RPS6KA3 P51812 Ribosomal protein S6 kinase alpha-3 chrX GO:0006915 Compendium Yes 106 0.143 145 18 0.124 13
RPS6KB1 RPS6KB1 P23443 Ribosomal protein S6 kinase beta-1 chr17 GO:0006915 Not Cancer Driver No 45 0.086 226 26 0.115 0
RRAGA RRAGA Q7L523 Ras-related GTP-binding protein A chr9 GO:0006915 Not Cancer Driver No 30 0.096 0 0 0.0 0
RRAGC RRAGC Q9HB90 Ras-related GTP-binding protein C chr1 GO:0006915 Compendium Yes 29 0.073 61 1 0.016 0
RRP1B RRP1B Q14684 Ribosomal RNA processing protein 1 homolog B chr21 GO:0006915 Not Cancer Driver No 74 0.098 513 48 0.094 0
RTKN RTKN Q9BST9 Rhotekin chr2 GO:0006915 Not Cancer Driver No 67 0.119 265 35 0.132 0
RTN3 RTN3 O95197 Reticulon-3 chr11 GO:0006915 Not Cancer Driver No 132 0.128 707 87 0.123 0
RTN4 RTN4 Q9NQC3 Reticulon-4 chr2 GO:0006915 Not Cancer Driver No 121 0.102 866 82 0.095 0
RYBP RYBP Q8N488 RING1 and YY1-binding protein chr3 GO:0006915 Not Cancer Driver No 37 0.162 214 37 0.173 0
RYR2 RYR2 Q92736 Ryanodine receptor 2 chr1 GO:0006915 Not Cancer Driver No 1703 0.343 782 281 0.359 51
S100A14_ENST00000368701 S100A14 Q9HCY8 Protein S100-A14 chr1 GO:0006915 Not Cancer Driver No 15 0.144 55 9 0.164 0
S100A8 S100A8 P05109 Protein S100-A8 chr1 GO:0006915 Not Cancer Driver No 22 0.237 8 4 0.5 0
S100A9 S100A9 P06702 Protein S100-A9 chr1 GO:0006915 Not Cancer Driver No 18 0.158 76 7 0.092 0
SAV1 SAV1 Q9H4B6 Protein salvador homolog 1 chr14 GO:0006915 Not Cancer Driver No 42 0.11 243 17 0.07 0
SCRIB_ENST00000320476 SCRIB Q14160 Protein scribble homolog chr8 GO:0006915 Not Cancer Driver No 196 0.12 1064 135 0.127 2
SEMA3A SEMA3A Q14563 Semaphorin-3A chr7 GO:0006915 Not Cancer Driver No 195 0.253 164 46 0.28 10
SEMA6A_ENST00000510263 SEMA6A Q9H2E6 Semaphorin-6A chr5 GO:0006915 Not Cancer Driver No 136 0.132 456 72 0.158 0
SEPT4_ENST00000317268 SEPTIN4 O43236 Septin-4 chr17 GO:0006915 Not Cancer Driver No 61 0.128 220 31 0.141 0
SERPINB9 SERPINB9 P50453 Serpin B9 chr6 GO:0006915 Not Cancer Driver No 64 0.17 22 2 0.091 0
SFRP2 SFRP2 Q96HF1 Secreted frizzled-related protein 2 chr4 GO:0006915 Not Cancer Driver No 47 0.159 1 0 0.0 0
SFRP5 SFRP5 Q5T4F7 Secreted frizzled-related protein 5 chr10 GO:0006915 Not Cancer Driver No 26 0.082 7 3 0.429 0
SGK1_ENST00000237305 SGK1 O00141 Serine/threonine-protein kinase Sgk1 chr6 GO:0006915 Census, Compendium Yes 58 0.135 86 16 0.186 0
SGMS1 SGMS1 Q86VZ5 Phosphatidylcholine:ceramide cholinephosphotransferase 1 chr10 GO:0006915 Not Cancer Driver No 85 0.206 37 8 0.216 0
SH3GLB1_ENST00000370558 SH3GLB1 Q9Y371 Endophilin-B1 chr1 GO:0006915 Not Cancer Driver No 41 0.112 82 10 0.122 0
SH3KBP1 SH3KBP1 Q96B97 SH3 domain-containing kinase-binding protein 1 chrX GO:0006915 Not Cancer Driver No 102 0.153 530 82 0.155 0
SH3RF3 SH3RF3 Q8TEJ3 E3 ubiquitin-protein ligase SH3RF3 chr2 GO:0006915 Not Cancer Driver No 98 0.111 564 53 0.094 0
SHB SHB Q15464 SH2 domain-containing adapter protein B chr9 GO:0006915 Not Cancer Driver No 56 0.11 334 36 0.108 0
SHC4 SHC4 Q6S5L8 SHC-transforming protein 4 chr15 GO:0006915 Not Cancer Driver No 74 0.117 325 44 0.135 0
SHF SHF Q7M4L6 SH2 domain-containing adapter protein F chr15 GO:0006915 Not Cancer Driver No 55 0.13 343 41 0.12 0
SIAH1_ENST00000394725 SIAH1 Q8IUQ4 E3 ubiquitin-protein ligase SIAH1 chr16 GO:0006915 Not Cancer Driver No 35 0.124 28 2 0.071 5
SIAH2 SIAH2 O43255 E3 ubiquitin-protein ligase SIAH2 chr3 GO:0006915 Not Cancer Driver No 48 0.148 68 3 0.044 0
SIX1_ENST00000645694 SIX1 Q15475 Homeobox protein SIX1 chr14 GO:0006915 Census, Compendium Yes 49 0.173 144 25 0.174 8
SIX3 SIX3 O95343 Homeobox protein SIX3 chr2 GO:0006915 Not Cancer Driver No 44 0.133 196 22 0.112 32
SLC1A1 SLC1A1 P43005 Excitatory amino acid transporter 3 chr9 GO:0006915 Not Cancer Driver No 69 0.132 17 4 0.235 1
SLC25A6 SLC25A6 P12236 ADP/ATP translocase 3 chrX GO:0006915 Not Cancer Driver No 41 0.138 0 0 0.0 0
SLC5A11 SLC5A11 Q8WWX8 Sodium/myo-inositol cotransporter 2 chr16 GO:0006915 Not Cancer Driver No 121 0.179 44 6 0.136 0
SLC5A8 SLC5A8 Q8N695 Sodium-coupled monocarboxylate transporter 1 chr12 GO:0006915 Not Cancer Driver No 156 0.256 33 10 0.303 0
SLIT2 SLIT2 O94813 Slit homolog 2 protein chr4 GO:0006915 Not Cancer Driver No 428 0.28 31 13 0.419 0
SLIT3_ENST00000519560 SLIT3 O75094 Slit homolog 3 protein chr5 GO:0006915 Not Cancer Driver No 351 0.23 40 9 0.225 0
SLK SLK Q9H2G2 STE20-like serine/threonine-protein kinase chr10 GO:0006915 Not Cancer Driver No 134 0.109 962 96 0.1 0
SLTM SLTM Q9NWH9 SAFB-like transcription modulator chr15 GO:0006915 Not Cancer Driver No 110 0.106 962 103 0.107 0
SMNDC1_ENST00000369592 SMNDC1 O75940 Survival of motor neuron-related-splicing factor 30 chr10 GO:0006915 Not Cancer Driver No 16 0.067 197 15 0.076 0
SNCA_ENST00000506244 SNCA P37840 Alpha-synuclein chr4 GO:0006915 Not Cancer Driver No 21 0.15 107 13 0.121 5
SPI1_ENST00000378538 SPI1 P17947 Transcription factor PU.1 chr11 GO:0006915 Not Cancer Driver No 46 0.17 187 34 0.182 0
SPIN2B_ENST00000275988 SPIN2B Q9BPZ2 Spindlin-2B chrX GO:0006915 Not Cancer Driver No 24 0.093 98 5 0.051 0
SQSTM1 SQSTM1 Q13501 Sequestosome-1 chr5 GO:0006915 Not Cancer Driver No 54 0.123 267 32 0.12 30
SRGN SRGN P10124 Serglycin chr10 GO:0006915 Not Cancer Driver No 25 0.158 87 13 0.149 0
STEAP3_ENST00000393107 STEAP3 Q658P3 Metalloreductase STEAP3 chr2 GO:0006915 Not Cancer Driver No 82 0.168 30 2 0.067 0
STK11 STK11 Q15831 Serine/threonine-protein kinase STK11 chr19 GO:0006915 Census, Compendium Yes 75 0.173 135 14 0.104 9
STK17A STK17A Q9UEE5 Serine/threonine-protein kinase 17A chr7 GO:0006915 Not Cancer Driver No 44 0.106 115 16 0.139 0
STK17B_ENST00000409228 STK17B O94768 Serine/threonine-protein kinase 17B chr2 GO:0006915 Not Cancer Driver No 57 0.153 60 12 0.2 0
STK26 STK26 Q9P289 Serine/threonine-protein kinase 26 chrX GO:0006915 Not Cancer Driver No 62 0.149 119 18 0.151 0
STK3_ENST00000419617 STK3 Q13188 Serine/threonine-protein kinase 3 chr8 GO:0006915 Not Cancer Driver No 70 0.143 241 32 0.133 0
STK4 STK4 Q13043 Serine/threonine-protein kinase 4 chr20 GO:0006915 Not Cancer Driver No 70 0.144 231 30 0.13 0
SUDS3 SUDS3 Q9H7L9 Sin3 histone deacetylase corepressor complex component SDS3 chr12 GO:0006915 Not Cancer Driver No 35 0.107 249 28 0.112 0
SULF1_ENST00000458141 SULF1 Q8IWU6 Extracellular sulfatase Sulf-1 chr8 GO:0006915 Not Cancer Driver No 246 0.282 269 71 0.264 0
TAF10 TAF10 Q12962 Transcription initiation factor TFIID subunit 10 chr11 GO:0006915 Not Cancer Driver No 17 0.078 131 4 0.031 0
TAF6_ENST00000344095 TAF6 P49848 Transcription initiation factor TFIID subunit 6 chr7 GO:0006915 Not Cancer Driver No 79 0.117 288 32 0.111 2
TAOK2 TAOK2 Q9UL54 Serine/threonine-protein kinase TAO2 chr16 GO:0006915 Not Cancer Driver No 191 0.155 666 102 0.153 0
TAX1BP1 TAX1BP1 Q86VP1 Tax1-binding protein 1 chr7 GO:0006915 Not Cancer Driver No 78 0.099 429 50 0.117 0
TBX1_ENST00000329705 TBX1 O43435 T-box transcription factor TBX1 chr22 GO:0006915 Not Cancer Driver No 35 0.088 197 12 0.061 4
TBX2 TBX2 Q13207 T-box transcription factor TBX2 chr17 GO:0006915 Not Cancer Driver No 74 0.104 401 36 0.09 1
TCHP_ENST00000405876 TCHP Q9BT92 Trichoplein keratin filament-binding protein chr12 GO:0006915 Not Cancer Driver No 60 0.12 356 50 0.14 0
TCIM TCIM Q9NR00 Transcriptional and immune response regulator chr8 GO:0006915 Not Cancer Driver No 21 0.198 33 7 0.212 0
TCIRG1 TCIRG1 Q13488 V-type proton ATPase 116 kDa subunit a 3 chr11 GO:0006915 Compendium Yes 68 0.082 102 6 0.059 5
TCTN3 TCTN3 Q6NUS6 Tectonic-3 chr10 GO:0006915 Not Cancer Driver No 45 0.074 71 8 0.113 1
TFDP1 TFDP1 Q14186 Transcription factor Dp-1 chr13 GO:0006915 Not Cancer Driver No 82 0.2 245 47 0.192 0
TGFBR1_ENST00000374994 TGFBR1 P36897 TGF-beta receptor type-1 chr9 GO:0006915 Not Cancer Driver No 86 0.171 23 3 0.13 15
TGFBR2_ENST00000295754 TGFBR2 P37173 TGF-beta receptor type-2 chr3 GO:0006915 Census, Compendium Yes 106 0.187 60 16 0.267 25
THOC1 THOC1 Q96FV9 THO complex subunit 1 chr18 GO:0006915 Not Cancer Driver No 55 0.084 280 26 0.093 0
THOC6 THOC6 Q86W42 THO complex subunit 6 homolog chr16 GO:0006915 Not Cancer Driver No 49 0.144 16 4 0.25 1
THRB_ENST00000415021 THRB P10828 Thyroid hormone receptor beta chr3 GO:0006915 Not Cancer Driver No 87 0.189 113 28 0.248 33
TIA1 TIA1 P31483 Cytotoxic granule associated RNA binding protein TIA1 chr2 GO:0006915 Not Cancer Driver No 39 0.101 130 12 0.092 2
TIAF1 MYO18A O95411 Putative TGFB1-induced anti-apoptotic factor 1 chr17 GO:0006915 Not Cancer Driver No 16 0.139 30 5 0.167 0
TIAL1_ENST00000436547 TIAL1 Q01085 Nucleolysin TIAR chr10 GO:0006915 Not Cancer Driver No 45 0.12 122 12 0.098 0
TIGAR TIGAR Q9NQ88 Fructose-2,6-bisphosphatase TIGAR chr12 GO:0006915 Not Cancer Driver No 44 0.163 39 9 0.231 0
TLR2 TLR2 O60603 Toll-like receptor 2 chr4 GO:0006915 Not Cancer Driver No 108 0.138 0 0 0.0 0
TMBIM4_ENST00000358230 TMBIM4 Q9HC24 Protein lifeguard 4 chr12 GO:0006915 Not Cancer Driver No 36 0.151 3 0 0.0 0
TMEM102 TMEM102 Q8N9M5 Transmembrane protein 102 chr17 GO:0006915 Not Cancer Driver No 38 0.075 141 13 0.092 0
TMEM14A TMEM14A Q9Y6G1 Transmembrane protein 14A chr6 GO:0006915 Not Cancer Driver No 10 0.101 0 0 0.0 0
TMEM214 TMEM214 Q6NUQ4 Transmembrane protein 214 chr2 GO:0006915 Not Cancer Driver No 68 0.099 123 9 0.073 0
TMEM219 TMEM219 Q86XT9 Insulin-like growth factor-binding protein 3 receptor chr16 GO:0006915 Not Cancer Driver No 15 0.062 20 1 0.05 0
TMTC4_ENST00000376234 TMTC4 Q5T4D3 Protein O-mannosyl-transferase TMTC4 chr13 GO:0006915 Not Cancer Driver No 105 0.142 0 0 0.0 0
TNF TNF P01375 Tumor necrosis factor chr6 GO:0006915 Not Cancer Driver No 24 0.103 45 3 0.067 0
TNFAIP1 TNFAIP1 Q13829 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 chr17 GO:0006915 Not Cancer Driver No 35 0.111 39 5 0.128 0
TNFAIP3 TNFAIP3 P21580 Tumor necrosis factor alpha-induced protein 3 chr6 GO:0006915 Census, Compendium Yes 98 0.124 231 33 0.143 1
TNFAIP8_ENST00000504771 TNFAIP8 O95379 Tumor necrosis factor alpha-induced protein 8 chr5 GO:0006915 Not Cancer Driver No 21 0.106 13 1 0.077 0
TNFRSF10A TNFRSF10A O00220 Tumor necrosis factor receptor superfamily member 10A chr8 GO:0006915 Not Cancer Driver No 55 0.118 174 17 0.098 0
TNFRSF10B TNFRSF10B O14763 Tumor necrosis factor receptor superfamily member 10B chr8 GO:0006915 Not Cancer Driver No 44 0.1 190 19 0.1 0
TNFRSF10D TNFRSF10D Q9UBN6 Tumor necrosis factor receptor superfamily member 10D chr8 GO:0006915 Not Cancer Driver No 51 0.132 193 28 0.145 0
TNFRSF11B TNFRSF11B O00300 Tumor necrosis factor receptor superfamily member 11B chr8 GO:0006915 Not Cancer Driver No 79 0.197 17 3 0.176 0
TNFRSF12A TNFRSF12A Q9NP84 Tumor necrosis factor receptor superfamily member 12A chr16 GO:0006915 Not Cancer Driver No 8 0.062 0 0 0.0 0
TNFRSF18_ENST00000379268 TNFRSF18 Q9Y5U5 Tumor necrosis factor receptor superfamily member 18 chr1 GO:0006915 Not Cancer Driver No 22 0.091 23 1 0.043 0
TNFRSF19 TNFRSF19 Q9NS68 Tumor necrosis factor receptor superfamily member 19 chr13 GO:0006915 Not Cancer Driver No 72 0.17 103 19 0.184 0
TNFRSF21 TNFRSF21 O75509 Tumor necrosis factor receptor superfamily member 21 chr6 GO:0006915 Not Cancer Driver No 98 0.15 280 46 0.164 0
TNFRSF25_ENST00000356876 TNFRSF25 Q93038 Tumor necrosis factor receptor superfamily member 25 chr1 GO:0006915 Not Cancer Driver No 38 0.091 72 6 0.083 0
TNFRSF6B TNFRSF6B O95407 Tumor necrosis factor receptor superfamily member 6B chr20 GO:0006915 Not Cancer Driver No 22 0.073 22 3 0.136 0
TNFRSF9 TNFRSF9 Q07011 Tumor necrosis factor receptor superfamily member 9 chr1 GO:0006915 Not Cancer Driver No 43 0.169 29 10 0.345 0
TNFSF10 TNFSF10 P50591 Tumor necrosis factor ligand superfamily member 10 chr3 GO:0006915 Not Cancer Driver No 43 0.153 61 7 0.115 0
TNFSF12 TNFSF12 O43508 Tumor necrosis factor ligand superfamily member 12 chr17 GO:0006915 Not Cancer Driver No 28 0.112 109 8 0.073 0
TNFSF14 TNFSF14 O43557 Tumor necrosis factor ligand superfamily member 14 chr19 GO:0006915 Not Cancer Driver No 58 0.242 18 1 0.056 0
TNFSF15 TNFSF15 O95150 Tumor necrosis factor ligand superfamily member 15 chr9 GO:0006915 Not Cancer Driver No 41 0.163 49 12 0.245 0
TNIP2 TNIP2 Q8NFZ5 TNFAIP3-interacting protein 2 chr4 GO:0006915 Not Cancer Driver No 43 0.1 316 36 0.114 0
TNS4 TNS4 Q8IZW8 Tensin-4 chr17 GO:0006915 Not Cancer Driver No 116 0.162 466 78 0.167 0
TOPAZ1 TOPAZ1 Q8N9V7 Protein TOPAZ1 chr3 GO:0006915 Not Cancer Driver No 110 0.065 814 61 0.075 0
TOX3 TOX3 O15405 TOX high mobility group box family member 3 chr16 GO:0006915 Not Cancer Driver No 85 0.148 485 72 0.148 0
TP53AIP1 TP53AIP1 Q9HCN2 p53-regulated apoptosis-inducing protein 1 chr11 GO:0006915 Not Cancer Driver No 5 0.04 51 3 0.059 0
TP53INP1 TP53INP1 Q96A56 Tumor protein p53-inducible nuclear protein 1 chr8 GO:0006915 Not Cancer Driver No 32 0.133 134 20 0.149 0
TP53_ENST00000445888 TP53 P04637 Cellular tumor antigen p53 chr17 GO:0006915 Census, Compendium Yes 2891 7.356 282 1466 5.199 83
TP63 TP63 Q9H3D4 Tumor protein 63 chr3 GO:0006915 Census, Compendium Yes 229 0.337 398 143 0.359 28
TPX2 TPX2 Q9ULW0 Targeting protein for Xklp2 chr20 GO:0006915 Not Cancer Driver No 92 0.123 695 86 0.124 0
TRADD TRADD Q15628 Tumor necrosis factor receptor type 1-associated DEATH domain protein chr16 GO:0006915 Not Cancer Driver No 26 0.083 74 5 0.068 0
TRAF1 TRAF1 Q13077 TNF receptor-associated factor 1 chr9 GO:0006915 Not Cancer Driver No 51 0.123 63 9 0.143 0
TRAF3IP2_ENST00000392556 TRAF3IP2 O43734 E3 ubiquitin ligase TRAF3IP2 chr6 GO:0006915 Not Cancer Driver No 59 0.103 410 39 0.095 2
TRAF3_ENST00000392745 TRAF3 Q13114 TNF receptor-associated factor 3 chr14 GO:0006915 Compendium Yes 61 0.107 101 9 0.089 1
TRAF4 TRAF4 Q9BUZ4 TNF receptor-associated factor 4 chr17 GO:0006915 Not Cancer Driver No 42 0.089 27 1 0.037 0
TRAF5_ENST00000336184 TRAF5 O00463 TNF receptor-associated factor 5 chr1 GO:0006915 Not Cancer Driver No 61 0.11 59 5 0.085 0
TRAF7 TRAF7 Q6Q0C0 E3 ubiquitin-protein ligase TRAF7 chr16 GO:0006915 Census Yes 76 0.113 120 14 0.117 4
TRAIP TRAIP Q9BWF2 E3 ubiquitin-protein ligase TRAIP chr3 GO:0006915 Not Cancer Driver No 63 0.134 240 33 0.138 1
TRIAP1 TRIAP1 O43715 TP53-regulated inhibitor of apoptosis 1 chr12 GO:0006915 Not Cancer Driver No 9 0.118 20 1 0.05 0
TRIM35 TRIM35 Q9UPQ4 E3 ubiquitin-protein ligase TRIM35 chr8 GO:0006915 Not Cancer Driver No 66 0.134 69 9 0.13 0
TRIM39 TRIM39 Q9HCM9 E3 ubiquitin-protein ligase TRIM39 chr6 GO:0006915 Not Cancer Driver No 74 0.143 62 8 0.129 0
TRIM69_ENST00000329464 TRIM69 Q86WT6 E3 ubiquitin-protein ligase TRIM69 chr15 GO:0006915 Not Cancer Driver No 78 0.156 62 15 0.242 0
TSC2 TSC2 P49815 Tuberin chr16 GO:0006915 Census, Compendium Yes 192 0.106 563 50 0.089 53
UBE2D3_ENST00000394801 UBE2D3 P61077 Ubiquitin-conjugating enzyme E2 D3 chr4 GO:0006915 Not Cancer Driver No 21 0.143 13 4 0.308 0
UBE2Z UBE2Z Q9H832 Ubiquitin-conjugating enzyme E2 Z chr17 GO:0006915 Not Cancer Driver No 27 0.076 140 10 0.071 0
UNC5A UNC5A Q6ZN44 Netrin receptor UNC5A chr5 GO:0006915 Not Cancer Driver No 133 0.158 120 20 0.167 0
UNC5B UNC5B Q8IZJ1 Netrin receptor UNC5B chr10 GO:0006915 Not Cancer Driver No 155 0.164 117 20 0.171 0
UNC5C UNC5C O95185 Netrin receptor UNC5C chr4 GO:0006915 Not Cancer Driver No 189 0.203 86 18 0.209 1
UNC5D UNC5D Q6UXZ4 Netrin receptor UNC5D chr8 GO:0006915 Not Cancer Driver No 292 0.306 194 44 0.227 0
USP17L1 USP17L1 Q7RTZ2 Ubiquitin carboxyl-terminal hydrolase 17-like protein 1 chr8 GO:0006915 Not Cancer Driver No 7 0.013 192 1 0.005 0
USP17L2 USP17L2 Q6R6M4 Ubiquitin carboxyl-terminal hydrolase 17 chr8 GO:0006915 Not Cancer Driver No 105 0.198 201 54 0.269 0
UXT_ENST00000333119 UXT Q9UBK9 Protein UXT chrX GO:0006915 Not Cancer Driver No 21 0.134 17 1 0.059 0
VDAC1_ENST00000395047 VDAC1 P21796 Voltage-dependent anion-selective channel protein 1 chr5 GO:0006915 Not Cancer Driver No 38 0.134 36 4 0.111 0
VIL1 VIL1 P09327 Villin-1 chr2 GO:0006915 Not Cancer Driver No 124 0.15 222 38 0.171 0
WDR92 DNAAF10 Q96MX6 Dynein axonemal assembly factor 10 chr2 GO:0006915 Not Cancer Driver No 36 0.101 42 6 0.143 0
XAF1 XAF1 Q6GPH4 XIAP-associated factor 1 chr17 GO:0006915 Not Cancer Driver No 28 0.093 106 13 0.123 0
XBP1 XBP1 P17861 X-box-binding protein 1 chr22 GO:0006915 Not Cancer Driver No 19 0.073 169 9 0.053 0
XKR4 XKR4 Q5GH76 XK-related protein 4 chr8 GO:0006915 Not Cancer Driver No 163 0.251 123 33 0.268 0
XKR5 XKR5 Q6UX68 XK-related protein 5 chr8 GO:0006915 Not Cancer Driver No 62 0.09 306 17 0.056 0
XKR6 XKR6 Q5GH73 XK-related protein 6 chr8 GO:0006915 Not Cancer Driver No 88 0.137 118 14 0.119 0
XKR7 XKR7 Q5GH72 XK-related protein 7 chr20 GO:0006915 Not Cancer Driver No 112 0.193 161 39 0.242 0
XKR8 XKR8 Q9H6D3 XK-related protein 8 chr1 GO:0006915 Not Cancer Driver No 34 0.086 4 0 0.0 0
XKR9 XKR9 Q5GH70 XK-related protein 9 chr8 GO:0006915 Not Cancer Driver No 72 0.193 0 0 0.0 0
YARS YARS1 P54577 Tyrosine--tRNA ligase, cytoplasmic chr1 GO:0006915 Not Cancer Driver No 62 0.117 109 9 0.083 3
ZBP1 ZBP1 Q9H171 Z-DNA-binding protein 1 chr20 GO:0006915 Not Cancer Driver No 97 0.226 385 80 0.208 0
ZBTB16_ENST00000392996 ZBTB16 Q05516 Zinc finger and BTB domain-containing protein 16 chr11 GO:0006915 Census, Compendium Yes 131 0.195 268 50 0.187 1
ZC3H12A ZC3H12A Q5D1E8 Endoribonuclease ZC3H12A chr1 GO:0006915 Not Cancer Driver No 90 0.15 396 44 0.111 0
ZC3H8 ZC3H8 Q8N5P1 Zinc finger CCCH domain-containing protein 8 chr2 GO:0006915 Not Cancer Driver No 22 0.076 187 17 0.091 0
ZDHHC16_ENST00000370854 ZDHHC16 Q969W1 Palmitoyltransferase ZDHHC16 chr10 GO:0006915 Not Cancer Driver No 41 0.109 9 1 0.111 0
ZFAND6 ZFAND6 Q6FIF0 AN1-type zinc finger protein 6 chr15 GO:0006915 Not Cancer Driver No 26 0.125 140 17 0.121 0
ZFP36L1 ZFP36L1 Q07352 mRNA decay activator protein ZFP36L1 chr14 GO:0006915 Compendium Yes 57 0.169 212 30 0.142 0
ZMAT3 ZMAT3 Q9HA38 Zinc finger matrin-type protein 3 chr3 GO:0006915 Not Cancer Driver No 48 0.166 217 41 0.189 0
ZMPSTE24 ZMPSTE24 O75844 CAAX prenyl protease 1 homolog chr1 GO:0006915 Not Cancer Driver No 67 0.141 23 0 0.0 3
ZNF385A ZNF385A Q96PM9 Zinc finger protein 385A chr12 GO:0006915 Not Cancer Driver No 43 0.111 312 34 0.109 0
ZNF443 ZNF443 Q9Y2A4 Zinc finger protein 443 chr19 GO:0006915 Not Cancer Driver No 101 0.151 129 18 0.14 0
ZPR1 ZPR1 O75312 Zinc finger protein ZPR1 chr11 GO:0006915 Not Cancer Driver No 38 0.083 291 27 0.093 0
ZSWIM2 ZSWIM2 Q8NEG5 E3 ubiquitin-protein ligase ZSWIM2 chr2 GO:0006915 Not Cancer Driver No 189 0.299 85 30 0.353 0